Cited by 575Body Composition Measurement TechniquesElectrical and Bioimpedance TomographyNutrition and Health in Aging

The DOI matches its Crossref record; 37 of the 42 references it cites were found in a registry or an index.

Single prediction equation for bioelectrical impedance analysis in adults aged 20–94 years

Kyle, Ursula G, Genton, Laurence, Karsegard, Laurie, Slosman, Daniel O, Pichard, Claude·2001·Nutrition

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Abstract

Existing equations for bioelectrical impedance analysis (BIA) are of limited use when subjects age or become overweight because these equations were developed in young, normal-weight subjects and are not valid in elderly or overweight people. The purpose of this study was to validate a single BIA equation in healthy white subjects aged 22--94 y with a body mass index between 17.0 and 33.8 kg/m(2). Healthy subjects (202 men and 141 women) aged 20--94 y were measured by two methods: fat-free mass (FFM) was measured by dual-energy x-ray absorptiometry (Hologic QDR-4500) and by a bioelectrical impedance analyzer (Xitron 4000B). Validity of BIA was assessed by double cross validation. Because correlations were high (r = 0.986--0.987) and prediction errors low, a single equation was developed using all subjects, as follows: FFM = -4.104 + (0.518 x height(2)/resistance) + (0.231 x weight) + (0.130 x reactance) + (4.229 x sex: men = 1, women = 0). FFM predicted with dual-energy x-ray absorptiometry was 54.0 +/- 10.7 kg. BIA-predicted FFM was 54.0 +/- 10.5 kg (r = 0.986, standard error of the estimate = 1.72 kg, technical error = 1.74 kg). In conclusion, the new Geneva BIA equation was valid for prediction of FFM in healthy adults aged 22--94 y with body mass indexes between 17.0 and 33.8 kg/m(2). Inclusion of reactance in the single prediction equation appeared to be essential for use of BIA equations in populations with large variations in age or body mass.

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Authors: Kyle, U. G., Genton, L., Karsegard, L., Slosman, D. O., & Pichard, C.
Affiliations: University Hospital of Geneva (CH)
ORCID: Genton, Laurence
Pichard, Claude
Venue: Nutrition
Publisher: Elsevier BV
Published: 2001-03
Volume: 17
Issue: 3
Pages: 248-253
ISSN: 0899-9007 (ISSN-L)
DOI: 10.1016/s0899-9007(00)00553-0
OpenAlex: W2041793073
Cited by: 575
References: 42
Citations by year: 2026: 13 · 2025: 19 · 2024: 26 · 2023: 24 · 2022: 28 · 2021: 39 · 2020: 27 · 2019: 31 · 2018: 34 · 2017: 35 · 2016: 32 · 2015: 35 · 2014: 35 · 2013: 26 · 2012: 33
FWCI: 7.95
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Nutrition (publishedVersion)
PubMed (publishedVersion)
Archive ouverte UNIGE (University of Geneva) (publishedVersion)
Archive ouverte UNIGE (University of Geneva) (submittedVersion)
Funders: Hôpitaux Universitaires de Genève
Topics: Health Sciences › Medicine › Physiology (medical) › Body Composition Measurement Techniques
Physical Sciences › Engineering › Electrical and Electronic Engineering › Electrical and Bioimpedance Tomography
Health Sciences › Medicine › Physiology (medical) › Nutrition and Health in Aging
Keywords: bioelectrical impedance analysis, fat-free mass, prediction equations, dual-energy X-ray absorptiometry, reactance, resistance, body mass index, older adults, overweight, validation, healthy adults
MeSH terms: Adult, Aged, Aged, 80 and over, Aging, Body Composition, Female, Humans, Male, Middle Aged, Reference Values, Regression Analysis, Reproducibility of Results, Absorptiometry, Photon, Body Mass Index, Electric Impedance

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Single prediction equation for bioelectrical impedance analysis in adults aged 20–94 years

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