Cited by 446Neuroscience and Neuropharmacology ResearchNeuroinflammation and Neurodegeneration MechanismsNeural dynamics and brain function

A neuron–glia signalling network in the active brain

Bezzi, Paola, Volterra, Andrea·2001·Current Opinion in Neurobiology

Abstract

Glial cells are active partners of neurons in processing information and synaptic integration. They receive coded signals from synapses and elaborate modulatory responses. The active properties of glia, including long-range signalling and regulated transmitter release, are beginning to be elucidated. Recent insights suggest that the active brain should no longer be regarded as a circuitry of neuronal contacts, but as an integrated network of interactive neurons and glia.

Integrity signals

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Crossref · 10.1016/s0959-4388(00)00223-3

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Authors
Bezzi, P., & Volterra, A.
Affiliations
University of Milan (IT)
Corresponding author
  • Bezzi, Paola
  • Volterra, Andrea
Venue
Current Opinion in Neurobiology
Publisher
Elsevier BV
Published
2001-06
Volume
11
Issue
3
Pages
387-394
ISSN
0959-4388 (ISSN-L)
OpenAlex
W2001537648
Cited by
446
References
62
Citations by year
2026: 8 · 2025: 10 · 2024: 10 · 2023: 17 · 2022: 15 · 2021: 12 · 2020: 12 · 2019: 13 · 2018: 17 · 2017: 17 · 2016: 22 · 2015: 15 · 2014: 17 · 2013: 13 · 2012: 17
FWCI
3.11
Type
journal article
Language
en
Open access
closed
Locations
  • Current Opinion in Neurobiology (publishedVersion)
  • PubMed (publishedVersion)
  • IRIS (submittedVersion)
  • IRIS Research product catalog (Sapienza University of Rome) (submittedVersion)
  • SERVAL (Université de Lausanne) (submittedVersion)
Funders
Istituto Superiore di Sanità
Topics
  • Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
  • Life Sciences › Neuroscience › Neurology › Neuroinflammation and Neurodegeneration Mechanisms
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Neural dynamics and brain function
Keywords
glial cells, synaptic integration, glial modulation
MeSH terms
Action Potentials, Animals, Brain, Calcium, Cell Communication, Cerebellum, Dopamine, Energy Metabolism, Exocytosis, Humans, Inflammation, Magnetic Resonance Imaging, Models, Neurological, Nerve Net, Synaptic Transmission, Neuroglia, Neuronal Plasticity, Neurons, Magnetic Resonance Spectroscopy, Retina, Dinoprostone, Signal Transduction, Gap Junctions, Neurotransmitter Agents, Rats

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