Synaptopathies: synaptic dysfunction in neurological disorders – A review from students to students

The Amyloid Hypothesis of Alzheimer’s Disease: Progress and Problems on the Road to Therapeutics

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Amyloid oligomers exacerbate tau pathology in a mouse model of tauopathy

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Gene Dose of Apolipoprotein E Type 4 Allele and the Risk of Alzheimer's Disease in Late Onset Families

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Epigenetic Regulations of GABAergic Neurotransmission: Relevance for Neurological Disorders and Epigenetic Therapy

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α-Synuclein in Lewy bodies

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Alzheimer's disease: the amyloid cascade hypothesis

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Global prevalence of dementia: a Delphi consensus study

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Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease

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Alzheimer's Disease Is a Synaptic Failure

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Physical basis of cognitive alterations in alzheimer's disease: Synapse loss is the major correlate of cognitive impairment

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Naturally secreted oligomers of amyloid β protein potently inhibit hippocampal long-term potentiation in vivo

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Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease

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Amyloid-β protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory

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Glutamate Receptor Ion Channels: Structure, Regulation, and Function

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Glycine potentiates the NMDA response in cultured mouse brain neurons

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Candidate gene for the chromosome 1 familial Alzheimer’s disease locus

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NMDA receptor subunit diversity: impact on receptor properties, synaptic plasticity and disease

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Synaptic Plasticity: Multiple Forms, Functions, and Mechanisms

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The Roles of PINK1, Parkin, and Mitochondrial Fidelity in Parkinson’s Disease

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Two Phase 3 Trials of Bapineuzumab in Mild-to-Moderate Alzheimer's Disease

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Reducing Endogenous Tau Ameliorates Amyloid ß-Induced Deficits in an Alzheimer's Disease Mouse Model

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Metabotropic Glutamate Receptors: Physiology, Pharmacology, and Disease

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High-Level Neuronal Expression of Aβ_1–42in Wild-Type Human Amyloid Protein Precursor Transgenic Mice: Synaptotoxicity without Plaque Formation

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Mutations of the X-linked genes encoding neuroligins NLGN3 and NLGN4 are associated with autism

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Dendritic Function of Tau Mediates Amyloid-β Toxicity in Alzheimer's Disease Mouse Models

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Axo-somatic and axo-dendritic synapses of the cerebral cortex: an electron microscope study.

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Thrombospondins are astrocyte-secreted proteins that promote CNS synaptogenesis

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Phase 3 Trials of Solanezumab for Mild-to-Moderate Alzheimer's Disease

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Frequency of Stages of Alzheimer-Related Lesions in Different Age Categories

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The synaptic vesicle protein SV2A is the binding site for the antiepileptic drug levetiracetam

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The mGluR theory of fragile X mental retardation

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Cellular prion protein mediates impairment of synaptic plasticity by amyloid-β oligomers

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Soluble Amyloid β Peptide Concentration as a Predictor of Synaptic Change in Alzheimer's Disease

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In vivo demonstration that α-synuclein oligomers are toxic

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Diffusion in Brain Extracellular Space

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Intraneuronal Aβ Causes the Onset of Early Alzheimer’s Disease-Related Cognitive Deficits in Transgenic Mice

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Multiplex Targeted Sequencing Identifies Recurrently Mutated Genes in Autism Spectrum Disorders

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The Intersection of Amyloid Beta and Tau at Synapses in Alzheimer’s Disease

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Homeostatic Synaptic Plasticity: Local and Global Mechanisms for Stabilizing Neuronal Function

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The Molecular and Systems Biology of Memory

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Alzheimer's disease-affected brain: Presence of oligomeric Aβ ligands (ADDLs) suggests a molecular basis for reversible memory loss

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α-Synuclein Cooperates with CSPα in Preventing Neurodegeneration

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Synaptic patterns on different cell types in the different laminae of the cat visual cortex. An electron microscope study

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A mouse model for Down syndrome exhibits learning and behaviour deficits

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Aβ Oligomers Induce Neuronal Oxidative Stress through an N-Methyl-D-aspartate Receptor-dependent Mechanism That Is Blocked by the Alzheimer Drug Memantine

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Soluble amyloid β-protein dimers isolated from Alzheimer cortex directly induce Tau hyperphosphorylation and neuritic degeneration

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An epigenetic blockade of cognitive functions in the neurodegenerating brain

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Astrocytes Control Synapse Formation, Function, and Elimination

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D-serine, an endogenous synaptic modulator: localization to astrocytes and glutamate-stimulated release

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Endocytic Pathway Abnormalities Precede Amyloid β Deposition in Sporadic Alzheimer’s Disease and Down Syndrome

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Neuroligins Determine Synapse Maturation and Function

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β-Amyloid1–42 Binds to α7 Nicotinic Acetylcholine Receptor with High Affinity

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Molecular structure and function of the glycine receptor chloride channel.

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Fibrillar amyloid-β burden in cognitively normal people at 3 levels of genetic risk for Alzheimer's disease

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Corelease of Two Fast Neurotransmitters at a Central Synapse

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The ADAMTS metalloproteinases

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Comorbidities of epilepsy: current concepts and future perspectives

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X-Linked Mental Retardation and Autism Are Associated with a Mutation in the NLGN4 Gene, a Member of the Neuroligin Family

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Perineuronal Nets Protect Fear Memories from Erasure

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Inhibitors of Class 1 Histone Deacetylases Reverse Contextual Memory Deficits in a Mouse Model of Alzheimer's Disease

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Relative Frequencies of Alzheimer Disease, Lewy Body, Vascular and Frontotemporal Dementia, and Hippocampal Sclerosis in the State of Florida Brain Bank

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Autistic-like social behaviour in Shank2-mutant mice improved by restoring NMDA receptor function

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Amyloid-β/Fyn–Induced Synaptic, Network, and Cognitive Impairments Depend on Tau Levels in Multiple Mouse Models of Alzheimer's Disease

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Calcium Channel Regulation and Presynaptic Plasticity

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Autistic-like behaviours and hyperactivity in mice lacking ProSAP1/Shank2

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Clinical and pathological features of a parkinsonian syndrome in a family with an Ala53Thr α‐synuclein mutation

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Neurexin mediates the assembly of presynaptic terminals

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The Postsynaptic Organization of Synapses

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Aβ induces astrocytic glutamate release, extrasynaptic NMDA receptor activation, and synaptic loss

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Activity-Dependent Validation of Excitatory versus Inhibitory Synapses by Neuroligin-1 versus Neuroligin-2

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Mutations causing syndromic autism define an axis of synaptic pathophysiology

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Direct Membrane Association Drives Mitochondrial Fission by the Parkinson Disease-associated Protein α-Synuclein*♦

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Oligomeric Aβ-induced synaptic dysfunction in Alzheimer’s disease

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Conserved epigenomic signals in mice and humans reveal immune basis of Alzheimer's disease

Gjoneska, E., Pfenning, A. R., Mathys, H., Quon, G., Kundaje, A., Tsai, L.-H., & Kellis, M. (2015) · Nature · doi:10.1038/nature14252 · Cited by 576 · see citing works

Metabotropic Glutamate Receptor 5 Is a Coreceptor for Alzheimer Aβ Oligomer Bound to Cellular Prion Protein

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Suppression of eIF2α kinases alleviates Alzheimer's disease–related plasticity and memory deficits

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Brain extracellular matrix affects AMPA receptor lateral mobility and short-term synaptic plasticity

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Caspase-3 Activation via Mitochondria Is Required for Long-Term Depression and AMPA Receptor Internalization

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Glycine receptor antibodies in PERM and related syndromes: characteristics, clinical features and outcomes

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The origin and evolution of synapses

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Detection of elevated levels of α-synuclein oligomers in CSF from patients with Parkinson disease

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RAB7L1 Interacts with LRRK2 to Modify Intraneuronal Protein Sorting and Parkinson’s Disease Risk

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Critical role of acetylation in tau-mediated neurodegeneration and cognitive deficits

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Pharmacotherapy for cognitive impairment in a mouse model of Down syndrome

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