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Untitled work

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p53-dependent release of Alarmin HMGB1 is a central mediator of senescent phenotypes

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Mesenchymal Stem Cells from Adipose Tissue in Clinical Applications for Dermatological Indications and Skin Aging

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Senescence mechanisms of nucleus pulposus chondrocytes in human intervertebral discs

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SIRT1 Overexpression Antagonizes Cellular Senescence with Activated ERK/S6k1 Signaling in Human Diploid Fibroblasts

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Dynamic Modelling of Pathways to Cellular Senescence Reveals Strategies for Targeted Interventions

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SGLT2 inhibition eliminates senescent cells and alleviates pathological aging

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Cancer and Aging - the Inflammatory Connection

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Cell Autonomous and non-autonomous effects of senescent cells in the skin

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Senolytics for Cancer Therapy: Is All that Glitters Really Gold?

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DNA Methylation Patterns Separate Senescence from Transformation Potential and Indicate Cancer Risk

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Distinct tumor suppressor mechanisms evolve in rodent species that differ in size and lifespan

Seluanov, A., Hine, C., Bozzella, M. J., Hall, A. W., Sasahara, T. H. D. C., Ribeiro, A. A. C. M., Catania, K. C., Presgraves, D. C., & Gorbunova, V. A. (2008) · Aging Cell · doi:10.1111/j.1474-9726.2008.00431.x · Cited by 122 · see citing works

Iron Deprivation in Cancer––Potential Therapeutic Implications

Heath, J. L., Weiss, J. M., Lavau, C., & Wechsler, D. S. (2013) · Nutrients · doi:10.3390/nu5082836 · Cited by 121 · see citing works

Senescent Keratinocytes Die by Autophagic Programmed Cell Death

Gosselin, K., Deruy, E., Martien, S., Vercamer, C., Bouali, F., Dujardin, T., Slomianny, C., Houel-Renault, L., Chelli, F., De Launoit, Y., et al. (2009) · The American Journal of Pathology · doi:10.2353/ajpath.2009.080332 · Cited by 119 · see citing works

Body language: the function of PML nuclear bodies in apoptosis regulation

Hofmann, T. G., & Will, H. (2003) · Cell Death and Differentiation · doi:10.1038/sj.cdd.4401313 · Cited by 118 · see citing works

Redox Control of Signal Transduction, Gene Expression and Cellular Senescence

Esposito, F., Ammendola, R., Faraonio, R., Russo, T., & Cimino, F. (2004) · Neurochemical Research · doi:10.1023/b:nere.0000014832.78725.1a · Cited by 113 · see citing works

Role of IFI 16, a member of the interferon-inducible p200-protein family, in prostate epithelial cellular senescence

Xin, H., Curry, J. L., Johnstone, R. W., Nickoloff, B. J., & Choubey, D. (2003) · Oncogene · doi:10.1038/sj.onc.1206754 · Cited by 114 · see citing works

Premature senescence is a primary fail-safe mechanism of ERBB2-driven tumorigenesis in breast carcinoma cells.

Trost, T. M., Lausch, E., Fees, S. A., Schmitt, S., Enklaar, T., Reutzel, D., Brixel, L., Schmidtke, P., Maringer, M., Schiffer, I., et al. (2005) · Cancer Research · doi:10.1158/0008-5472.840.65.3 · Cited by 99 · see citing works

MDC1/NFBD1: a key regulator of the DNA damage response in higher eukaryotes

Stucki, M., & Jackson, S. P. (2004) · DNA repair · doi:10.1016/j.dnarep.2004.03.007 · Cited by 111 · see citing works

Telomere length measurements in leukocyte subsets by automated multicolor flow‐FISH

Baerlocher, G. M., & Lansdorp, P. M. (2003) · Cytometry Part A · doi:10.1002/cyto.a.10064 · Cited by 112 · see citing works

Premature senescence of endothelial cells: Methusaleh's dilemma

Chen, J., & Goligorsky, M. S. (2006) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.01103.2005 · Cited by 110 · see citing works

Inflammation and Cancer: Is the Link as Simple as We Think?

Nickoloff, B. J., Ben-Neriah, Y., & Pikarsky, E. (2005) · Journal of Investigative Dermatology · doi:10.1111/j.0022-202x.2005.23724.x · Cited by 110 · see citing works

Depletion of SIRT6 causes cellular senescence, DNA damage, and telomere dysfunction in human chondrocytes

Nagai, K., Matsushita, T., Matsuzaki, T., Takayama, K., Matsumoto, T., Kuroda, R., & Kurosaka, M. (2015) · Osteoarthritis and Cartilage · doi:10.1016/j.joca.2015.03.024 · Cited by 108 · see citing works

Diversity of the Senescence Phenotype of Cancer Cells Treated with Chemotherapeutic Agents

Bojko, A., Czarnecka‐Herok, J., Charzyńska, A., Dąbrowski, M., & Sikora, E. (2019) · Cells · doi:10.3390/cells8121501 · Cited by 109 · see citing works

Genetic Manipulation of Telomerase in HIV-Specific CD8+ T Cells: Enhanced Antiviral Functions Accompany the Increased Proliferative Potential and Telomere Length Stabilization

Dagarag, M. D., Evazyan, T., Rao, N. P., & Effros, R. B. (2004) · The Journal of Immunology · doi:10.4049/jimmunol.173.10.6303 · Cited by 107 · see citing works

Senescence-Associated Oxidative DNA Damage Promotes the Generation of Neoplastic Cells

Gosselin, K., Martien, S., Pourtier, A., Vercamer, C., Ostoich, P. V., Morat, L., Sabatier, L., Duprez, L., de Roodenbeke, C. T., Gilson, É., et al. (2009) · Cancer Research · doi:10.1158/0008-5472.can-08-2510 · Cited by 109 · see citing works

Mechanisms shaping the role of ERK1/2 in cellular sene scence (Review)

Zou, J., Lei, T., Guo, P., Yu, J., Xu, Q., Luo, Y., Ke, R., & Huang, D. (2018) · Molecular Medicine Reports · doi:10.3892/mmr.2018.9712 · Cited by 107 · see citing works

Telomere length mediates the effects of telomerase on the cellular response to genotoxic stress

Rubio, M. Á., Davalos, A. R., & Campisi, J. (2004) · Experimental Cell Research · doi:10.1016/j.yexcr.2004.04.004 · Cited by 105 · see citing works

Caveolin-1 Regulates the Antagonistic Pleiotropic Properties of Cellular Senescence through a Novel Mdm2/p53-Mediated Pathway

Bartholomew, J. N., Volonté, D., & Galbiati, F. (2009) · Cancer Research · doi:10.1158/0008-5472.can-08-2857 · Cited by 106 · see citing works

Nicotinamide extends replicative lifespan of human cells

Kang, H. T., Lee, H. I., & Hwang, E. S. (2006) · Aging Cell · doi:10.1111/j.1474-9726.2006.00234.x · Cited by 105 · see citing works

Telomeres shorten more slowly in slow-aging wild animals than in fast-aging ones

Dantzer, B., & Fletcher, Q. E. (2015) · Experimental Gerontology · doi:10.1016/j.exger.2015.08.012 · Cited by 102 · see citing works

Epstein-Barr virus LMP1 blocks p16INK4a–RB pathway by promoting nuclear export of E2F4/5

Ohtani, N., Brennan, P., Gaubatz, S., Sanij, E., Hertzog, P. J., Wolvetang, E. J., Ghysdael, J., Rowe, M., & Hara, E. (2003) · The Journal of Cell Biology · doi:10.1083/jcb.200302085 · Cited by 103 · see citing works

Senescence Mediates Pituitary Hypoplasia and Restrains Pituitary Tumor Growth

Chesnokova, V., Zonis, S., Rubinek, T., Yu, R., Ben-Shlomo, A., Kovács, K., Wawrowsky, K., & Melmed, S. K. (2007) · Cancer Research · doi:10.1158/0008-5472.can-07-0974 · Cited by 105 · see citing works

Cellular lifespan and senescence signaling in embryonic stem cells

Miura, T., Mattson, M. P., & Rao, M. S. (2004) · Aging Cell · doi:10.1111/j.1474-9728.2004.00134.x · Cited by 102 · see citing works

miR-127 Regulates Cell Proliferation and Senescence by Targeting BCL6

Chen, J., Wang, M., Guo, M., Xie, Y., & Cong, Y. (2013) · PLoS ONE · doi:10.1371/journal.pone.0080266 · Cited by 102 · see citing works

Cellular senescence and tumor promotion: Is aging the key?

Loaiza, N., & Demaria, M. (2016) · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer · doi:10.1016/j.bbcan.2016.01.007 · Cited by 101 · see citing works

DNA damage response of A549 cells treated with particulate matter (PM 10 ) of urban air pollutants

Sánchez-Pérez, Y., Chirino, Y. I., Osornio-Vargas, Á. R., Morales‐Bárcenas, R., Gutiérrez‐Ruíz, M. C., Vázquez‐López, I., & García-Cuellar, C. M. (2009) · Cancer Letters · doi:10.1016/j.canlet.2009.01.010 · Cited by 100 · see citing works

Male age, germline mutations and the benefits of polyandry

Radwan, J. (2003) · Ecology Letters · doi:10.1046/j.1461-0248.2003.00484.x · Cited by 99 · see citing works

Differential Roles for the Interferon-Inducible IFI16 and AIM2 Innate Immune Sensors for Cytosolic DNA in Cellular Senescence of Human Fibroblasts

Duan, X., Ponomareva, L. V., Veeranki, S., Panchanathan, R., Dickerson, E., & Choubey, D. (2011) · Molecular Cancer Research · doi:10.1158/1541-7786.mcr-10-0565 · Cited by 95 · see citing works

Emerging roles of RB family: New defense mechanisms against tumor progression

Indovina, P., Marcelli, E., Casini, N., Rizzo, V., & Giordano, A. (2012) · Journal of Cellular Physiology · doi:10.1002/jcp.24170 · Cited by 94 · see citing works

Immortalization of Cementoblast Progenitor Cells With Bmi-1 and TERT

Saito, M., Handa, K., Kiyono, T., Hattori, S., Yokoi, T., Tsubakimoto, T., Harada, H., Noguchi, T., Toyoda, M., Sato, S., et al. (2005) · Journal of Bone and Mineral Research · doi:10.1359/jbmr.041006 · Cited by 93 · see citing works

Human fibroblasts require the Rb family of tumor suppressors, but not p53, for PML-induced senescence

Mallette, F. A., Goumard, S., Gaumont‐Leclerc, M., Moiseeva, O. V., & Ferbeyre, G. (2004) · Oncogene · doi:10.1038/sj.onc.1206886 · Cited by 93 · see citing works

Untitled work

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Cellular senescence and tumor suppression

Adams, P. D. (2010)

Cellular senescence: putting the paradoxes in perspective

Campisi, J. (2011) · Current Opinion in Genetics &amp; Development · doi:10.1016/j.gde.2010.10.005 · Cited by 368 · see citing works

Unraveling the nexus between cellular senescence and malignant transformation: a paradigm shift in cancer research

Song, X., Liu, X.-Y., Guo, Q., Xu, H., & Cao, L. (2024) · Cancer Biology and Medicine · doi:10.20892/j.issn.2095-3941.2024.0157 · Cited by 4 · see citing works

Une re-vue de la sénescence cellulaire

Bischof, O., Dejean, A., & Pineau, P. (2009) · médecine/sciences · doi:10.1051/medsci/2009252153 · Cited by 21 · see citing works