Effects of Cyclic GMP on Smooth Muscle Relaxation
Abstract
Cyclic GMP levels within smooth muscle are affected then by a number of different pathways. Physiologically NO and ANF are probably the two most important regulators for smooth muscle function, but a variety of other mediators and pharmacological agents may also influence this system. Because of the important role that cyclic GMP plays in the control of smooth muscle tone, which clearly includes vascular smooth muscle, it is now and will continue to be in the future an important physiological and biochemical target for research and a pharmacological target for therapeutic agents.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The molybdopterin cofactor of sulfite oxidase catalyzes nitrite reduction to produce NO.
“Like XO and AO, the molybdopterin cofactor of sulfite oxidase is able to catalyze nitrite reduction to produce NO (Table 4) (990).”
From Sources of Vascular Nitric Oxide and Reactive Oxygen Species and Their Regulation (2019) · cites this paper as [990]
All four mammalian molybdenum-containing enzymes (XO, AO, sulfite oxidase, and mARC) are able to reduce nitrite at different intrinsic rates.
“Subsequently, several reports have shown that all mammalian Mo-containing enzymes [XO, aldehyde oxidase (AO), sulfite oxidase, and the mitochondrial amidoxime-reducing component (mARC)] are able to reduce nitrite at different intrinsic rates (Table 4) (575, 880, 990).”
From Sources of Vascular Nitric Oxide and Reactive Oxygen Species and Their Regulation (2019) · cites this paper as [990]
Cites
Furchgott, R. F., & Zawadzki, J. V. (1980) · Nature · doi:10.1038/288373a0 · Cited by 12,064 · see citing works
Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor
Palmer, R. M. J., Ferrige, A. G., & Moncada, S. (1987) · Nature · doi:10.1038/327524a0 · Cited by 10,704 · see citing works
Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide.
Ignarro, L. J., Buga, G. M., Wood, K. S., Byrns, R. E., & Chaudhuri, G. (1987) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.84.24.9265 · Cited by 5,074 · see citing works
Vascular endothelial cells synthesize nitric oxide from L-arginine
Palmer, R. M. J., Ashton, D., & Moncada, S. (1988) · Nature · doi:10.1038/333664a0 · Cited by 4,745 · see citing works
de Bold, A. J., Borenstein, H., Veress, A. T., & Sonnenberg, H. (1981) · Life Sciences · doi:10.1016/0024-3205(81)90370-2 · Cited by 3,144 · see citing works
Role of endothelium-derived nitric oxide in the regulation of blood pressure.
Rees, D. D., Palmer, R. M. J., & Moncada, S. (1989) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.86.9.3375 · Cited by 1,827 · see citing works
A new natriuretic peptide in porcine brain
Sudoh, T., Kangawa, K., Minamino, N., & Matsuo, H. (1988) · Nature · doi:10.1038/332078a0 · Cited by 1,811 · see citing works
Ignarro, L. J., Lippton, H., Edwards, J. C., Baricos, W. H., Hyman, A. L., Kadowitz, P. J., & Gruetter, C. A. (1981) · The Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)32738-2 · Cited by 1,633 · see citing works
Macrophage cytotoxicity: role for L-arginine deiminase and imino nitrogen oxidation to nitrite
Hibbs, J. B., Taintor, R. R., & Vavrin, Z. (1987) · Science · doi:10.1126/science.2432665 · Cited by 1,527 · see citing works
Arnold, W. P., Mittal, C. K., Katsuki, S., & Murad, F. (1977) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.74.8.3203 · Cited by 1,459 · see citing works
Self-citationPalmer, R. M. J., Rees, D. D., Ashton, D. S., & Moncada, S. (1988) · Biochemical and Biophysical Research Communications · doi:10.1016/s0006-291x(88)81362-7 · Cited by 1,348 · see citing works
Martin, W., Villani, G. M., Jothianandan, D., & Furchgott, R. F. (1985) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)20898-9 · Cited by 1,259 · see citing works
Sudoh, T., Minamino, N., Kangawa, K., & Matsuo, H. (1990) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(90)92401-k · Cited by 1,097 · see citing works
Nitric oxide as an inhibitory non-adrenergic non-cholinergic neurotransmitter
Bult, H., Boeckxstaens, G. E., Pelckmans, P. A., Jordaens, F. H., Maercke, Y. M. V., & Herman, A. G. (1990) · Nature · doi:10.1038/345346a0 · Cited by 993 · see citing works
A membrane form of guanylate cyclase is an atrial natriuretic peptide receptor
Chinkers, M., Garbers, D. L., Chang, M., Lowe, D. G., Chin, H. R., Goeddel, D. V., & Schulz, S. (1989) · Nature · doi:10.1038/338078a0 · Cited by 992 · see citing works
Pollock, J. S., Förstermann, U., Mitchell, J. A., Warner, T. D., Schmidt, H. H. H. W., Nakane, M., & Murad, F. (1991) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.88.23.10480 · Cited by 979 · see citing works
Self-citationAgonist-induced endothelium-dependent relaxation in rat thoracic aorta may be mediated through cGMP
Rapoport, R. M., & Murad, F. (1983) · Circulation Research · doi:10.1161/01.res.52.3.352 · Cited by 928 · see citing works
Self-citationCyclic GMP synthesis and function.
Waldman, S. A., & Murad, F. (1987) · Pharmacological Reviews · doi:10.1016/s0031-6997(25)06656-6 · Cited by 859 · see citing works
Self-citationIgnarro, L. J., Bush, M. A., Buga, G. M., Wood, K. S., Fukuto, J. M., & Rajfer, J. (1990) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(90)92168-y · Cited by 832 · see citing works
Cyclic guanosine monophosphate as a mediator of vasodilation.
Murad, F. (1986) · Journal of Clinical Investigation · doi:10.1172/jci112536 · Cited by 799 · see citing works
Self-citationSelective Activation of the B Natriuretic Peptide Receptor by C-Type Natriuretic Peptide (CNP)
Koller, K. J., Lowe, D. G., Bennett, G. L., Minamino, N., Kangawa, K., Matsuo, H., & Goeddel, D. V. (1991) · Science · doi:10.1126/science.1672777 · Cited by 724 · see citing works
Glauser, M. P., Zanetti, G. M. R., Baumgartner, J. D., & Cohen, J. (1991) · The Lancet · doi:10.1016/0140-6736(91)91452-z · Cited by 716 · see citing works
Bioactive Cardiac Substances: Potent Vasorelaxant Activity in Mammalian Atria
Currie, M. G., Geller, D. M., Cole, B. R., Boylan, J. G., YuSheng, W., Holmberg, S. W., & Needleman, P. (1983) · Science · doi:10.1126/science.6857267 · Cited by 709 · see citing works
Katsuki, S., Arnold, W. P., Mittal, C. K., & Murad, F. (1977) · PubMed · Cited by 701 · see citing works
Self-citationInduction of nitric oxide synthase by cytokines in vascular smooth muscle cells
Busse, R., & Mülsch, A. (1990) · FEBS Letters · doi:10.1016/0014-5793(90)81445-t · Cited by 698 · see citing works
Waldman, S. A., Rapoport, R. M., & Murad, F. (1984) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)42597-x · Cited by 675 · see citing works
Self-citationRapoport, R. M., Draznin, M. B., & Murad, F. (1983) · Nature · doi:10.1038/306174a0 · Cited by 631 · see citing works
Self-citationChang, M.-S., Lowe, D. G., Lewis, M., Hellmiss, R., Chen, E., & Goeddel, D. V. (1989) · Nature · doi:10.1038/341068a0 · Cited by 581 · see citing works
Natanson, C., Eichenholz, P. W., Danner, R. L., Eichacker, P. Q., Hoffman, W. D., Kuo, G. C., Banks, S. M., MacVittie, T. J., & Parrillo, J. E. (1989) · The Journal of Experimental Medicine · doi:10.1084/jem.169.3.823 · Cited by 566 · see citing works
Gruetter, C. A., Gruetter, D. Y., Lyon, J., Kadowitz, P. J., & Ignarro, L. J. (1981) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)32778-3 · Cited by 533 · see citing works
Involvement of nitric oxide in the reflex relaxation of the stomach to accommodate food or fluid
Desai, K., Sessa, W., & Vane, J. (1991) · Nature · doi:10.1038/351477a0 · Cited by 525 · see citing works
Winquist, R. J., Faison, E. P., Waldman, S. A., Schwartz, K., Murad, F., & Rapoport, R. M. (1984) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.81.23.7661 · Cited by 497 · see citing works
Self-citationLoss of vascular responsiveness induced by endotoxin involves L-arginine pathway
Julou‐Schaeffer, G., Gray, G. A., Fleming, I., Schott, C., Parratt, J. R., & Stoclet, J. C. (1990) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.1990.259.4.h1038 · Cited by 461 · see citing works
Murad, F., Mittal, C. K., Arnold, W. P., Katsuki, S., & Kimura, H. (1978) · PubMed · Cited by 446 · see citing works
Self-citationGruetter, C. A., Barry, B. K., McNamara, D. B., Gruetter, D. Y., Kadowitz, P. J., & Ignarro, L. J. (1979) · PubMed · Cited by 444 · see citing works
Identification of arginine as a precursor of endothelium-derived relaxing factor.
Sakuma, I., Stuehr, D. J., Gross, S. S., Nathan, C., & Levi, R. (1988) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.85.22.8664 · Cited by 401 · see citing works
Beasley, D., Schwartz, J. H., & Brenner, B. M. (1991) · Journal of Clinical Investigation · doi:10.1172/jci115036 · Cited by 398 · see citing works
Guang, L. C., & Rand, M. J. (1990) · European Journal of Pharmacology · doi:10.1016/0014-2999(90)94162-q · Cited by 394 · see citing works
Lowe, D. G., Chang, M. S., Hellmiss, R., Chen, E., Singh, S., Garbers, D. L., & Goeddel, D. V. (1989) · The EMBO Journal · doi:10.1002/j.1460-2075.1989.tb03518.x · Cited by 371 · see citing works
ATRIAL NATRIURETIC FACTOR AND RELATED PEPTIDE HORMONES
Rosenzweig, A., & Seidman, C. E. (1991) · Annual Review of Biochemistry · doi:10.1146/annurev.bi.60.070191.001305 · Cited by 368 · see citing works
The rat anococcygeus muscle and its response to nerve stimulation and to some drugs
GILLESPIE, J. S. (1972) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.1972.tb08097.x · Cited by 361 · see citing works
(1991) · doi:10.1172/jci115266 · Cited by 354 · see citing works
Kuno, T., Andresen, J. W., Kamisaki, Y., Waldman, S. A., Chang, L. Y., Saheki, S., Leitman, D. C., Nakane, M., & Murad, F. (1986) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)38456-9 · Cited by 341 · see citing works
Self-citationEndothelial Cells as Mediators of Vasodilation of Arteries
Furchgott, R. F., Cherry, P. D., Zawadzki, J. V., & Jothianandan, D. (1984) · Journal of Cardiovascular Pharmacology · doi:10.1097/00005344-198406002-00008 · Cited by 322 · see citing works
Gruetter, C. A., Kadowitz, P. J., & Ignarro, L. J. (1981) · Canadian Journal of Physiology and Pharmacology · doi:10.1139/y81-025 · Cited by 316 · see citing works
Regulation of Intracellular Ca2+ Levels in Cultured Vascular Smooth Muscle Cells
Cornwell, T. L., & Lincoln, T. (1989) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)85065-2 · Cited by 314 · see citing works
Gillespie, J. S., Liu, X., & Martin, W. (1989) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.1989.tb12650.x · Cited by 308 · see citing works
Katsuki, S., & Murad, F. (1977) · Molecular Pharmacology · doi:10.1016/s0026-895x(25)11207-8 · Cited by 293 · see citing works
Self-citationFörstermann, U., Mülsch, A., Böhme, E., & Busse, R. (1986) · Circulation Research · doi:10.1161/01.res.58.4.531 · Cited by 288 · see citing works
Kleinert, H. D., Maack, T., Atlas, S. A., Januszewicz, M., Sealey, J. E., & Laragh, J. H. (1984) · Hypertension · doi:10.1161/01.hyp.6.2_pt_2.i143 · Cited by 286 · see citing works
Rapoport, R. M. (1986) · Circulation Research · doi:10.1161/01.res.58.3.407 · Cited by 280 · see citing works
Electron microscopy of the atrium of the heart. I. Guinea pig.
Kisch, B. (1956) · PubMed · Cited by 265 · see citing works
Brain natriuretic peptide is a novel cardiac hormone
Saito, Y., Nakao, K., Itoh, H., Yamada, T., Mukoyama, M., Arai, H., Hosoda, K., Shirakami, G., Suga, S., Minamino, N., et al. (1989) · Biochemical and Biophysical Research Communications · doi:10.1016/s0006-291x(89)80056-7 · Cited by 258 · see citing works
Cyclic GMP and mechanisms of vasodilation
Lincoln, T. (1989) · Pharmacology & Therapeutics · doi:10.1016/0163-7258(89)90127-7 · Cited by 250 · see citing works
Organic nitrate esters: clinical use and mechanisms of actions.
Ahlner, J., Andersson, R., Torfgård, K., & Axelsson, K. L. (1991) · Pharmacological Reviews · doi:10.1016/s0031-6997(25)06667-0 · Cited by 243 · see citing works
Boeckxstaens, G. E., Pelckmans, P. A., Bogers, J., Bult, H., Man, J. G. D., Oosterbosch, L., Herman, A. G., & Maercke, Y. M. V. (1990) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)22948-2 · Cited by 241 · see citing works
Cook, N. J., Hanke, W. R. L., & Kaupp, U. B. (1987) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.84.2.585 · Cited by 236 · see citing works
Ignarro, L. J. (1990) · Pharmacology & Toxicology · doi:10.1111/j.1600-0773.1990.tb00772.x · Cited by 229 · see citing works
Activation of guanylate cyclase from rat liver and other tissues by sodium azide.
Kimura, H., Ck, M., & Murad, F. (1975) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)40809-0 · Cited by 226 · see citing works
Self-citationSoluble guanylate cyclase from rat lung exists as a heterodimer.
Kamisaki, Y., Saheki, S., Nakane, M., Palmieri, J. A., Kuno, T., Chang, B., Waldman, S. A., & Murad, F. (1986) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)38380-1 · Cited by 226 · see citing works
Self-citationRaeymaekers, L., Hofmann, F. B., & Casteels, R. (1988) · Biochemical Journal · doi:10.1042/bj2520269 · Cited by 226 · see citing works
Tucker, J. F., Brave, S. R., Charalambous, L., Hobbs, A. J., & Gibson, A. (1990) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.1990.tb14072.x · Cited by 222 · see citing works
Molecular cloning and expression of cDNAs coding for soluble guanylate cyclase from rat lung.
Nakane, M., Arai, K., Saheki, S., Kuno, T., Buechler, W. A., & Murad, F. (1990) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)44837-x · Cited by 219 · see citing works
Self-citationThe Regulation of the Na+ ‐Ca2+ Exchanger of Heart Sarcolemma
Caroni, P., & Carafoli, E. (1983) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1983.tb07383.x · Cited by 212 · see citing works
Vasodilator profile of synthetic atrial natriuretic factor
Winquist, R. J., Faison, E. P., & Nutt, R. F. (1984) · European Journal of Pharmacology · doi:10.1016/0014-2999(84)90353-4 · Cited by 211 · see citing works
Zimmerman, A. L., Yamanaka, G. A., Eckstein, F., Baylor, D. A., & Stryer, L. (1985) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.82.24.8813 · Cited by 208 · see citing works
Katsuki, S., Arnold, W. P., & Murad, F. (1977) · PubMed · Cited by 206 · see citing works
Self-citationHirata, M., Kohse, K. P., Chang, C., Ikebe, T., & Murad, F. (1990) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)40008-2 · Cited by 201 · see citing works
Self-citationGibson, A., Mirzazadeh, S., Hobbs, A. J., & Moore, P. K. (1990) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.1990.tb12976.x · Cited by 198 · see citing works
Vasodilatation: Vascular Smooth Muscle, Peptides, Autonomic Nerves, and Endothelium
Coffman, J. D. (1989) · Mayo Clinic Proceedings · doi:10.1016/s0025-6196(12)61768-6 · Cited by 192 · see citing works
Incubation with endotoxin activates the L-arginine pathway in vascular tissue
Fleming, I., Gray, G. A., Julou‐Schaeffer, G., Parratt, J. R., & Stoclet, J. (1990) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(90)91183-s · Cited by 192 · see citing works
Furukawa, K.-L., Tawada, Y., & Shigekawa, M. (1988) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)68441-8 · Cited by 188 · see citing works
Lincoln, T., & Cornwell, T. L. (2008) · Blood Vessels · doi:10.1159/000158852 · Cited by 187 · see citing works
Twort, C. H. C., & van Breemen, C. (1988) · Circulation Research · doi:10.1161/01.res.62.5.961 · Cited by 184 · see citing works
The mechanism of cGMP-induced relaxation in vascular smooth muscle
Popescu, L. M., Pănoiu, C., Hinescu, M. E., & Nutu, O. (1985) · European Journal of Pharmacology · doi:10.1016/0014-2999(85)90269-9 · Cited by 179 · see citing works
Vascular smooth muscle-derived relaxing factor (MDRF) and its close similarity to nitric oxide
Wood, K. S., Buga, G. M., Byrns, R. E., & Ignarro, L. J. (1990) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(90)91243-l · Cited by 177 · see citing works
Possible involvement of S‐nitrosothiols in the activation of guanylate cyclase by nitroso compounds
Ignarro, L. J., Edwards, J. C., Gruetter, D. Y., Barry, B. K., & Gruetter, C. A. (1980) · FEBS Letters · doi:10.1016/0014-5793(80)80091-3 · Cited by 174 · see citing works
Cloning and sequence analysis of cDNA encoding a precursor for rat brain natriuretic peptide
Kojima, M., Minamino, N., Kangawa, J., & Matsuo, H. (1989) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(89)92268-7 · Cited by 171 · see citing works
Expression of soluble guanylyl cyclase
Harteneck, C., Koesling, D., Söling, A., Schultz, G., & Böhme, E. (1990) · FEBS Letters · doi:10.1016/0014-5793(90)80489-6 · Cited by 170 · see citing works
Lincoln, T., Dills, W. L., & Corbin, J. D. (1977) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)40260-2 · Cited by 166 · see citing works
Expression of soluble guanylate cyclase activity requires both enzyme subunits
Buechler, W. A., Nakane, M., & Murad, F. (1991) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(91)90527-e · Cited by 160 · see citing works
Self-citationCharacterization of a novel isozyme of cGMP-dependent protein kinase from bovine aorta
Wolfe, L., Corbin, J. D., & Francis, S. H. (1989) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)83296-3 · Cited by 158 · see citing works
Desensitization to nitroglycerin in vascular smooth muscle from rat and human
Waldman, S. A., Rapoport, R. M., Ginsburg, R., & Murad, F. (1986) · Biochemical Pharmacology · doi:10.1016/0006-2952(86)90622-2 · Cited by 153 · see citing works
Self-citationHarder, D. R., Belardinelli, L., Sperelakis, N., Rubio, R., & Berne, R. M. (1979) · Circulation Research · doi:10.1161/01.res.44.2.176 · Cited by 145 · see citing works
The primary structure of the 70 kDa subunit of bovine soluble guanylate cyclase
Koesling, D., Herz, J., Gausepohlꝉ, H., Niroomand, F., Hinsch, K., Mülsch, A., Böhme, E., Schultz, G., & Frank, R. W. (1988) · FEBS Letters · doi:10.1016/0014-5793(88)80539-8 · Cited by 142 · see citing works
Nakane, M., Saheki, S., Kuno, T., Ishii, K., & Murad, F. (1988) · Biochemical and Biophysical Research Communications · doi:10.1016/s0006-291x(88)80992-6 · Cited by 140 · see citing works
Self-citationToda, N., Baba, H., & Okamura, T. (1990) · The Japanese Journal of Pharmacology · doi:10.1254/jjp.53.281 · Cited by 139 · see citing works
Corbin, J. D., Øgreid, D., Miller, J. P., Suva, R. H., Jastorff, B., & Døskeland, S. O. (1986) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)36077-5 · Cited by 136 · see citing works
Vrolix, M., Raeymaekers, L., Wuytack, F., Hofmann, F. B., & Casteels, R. (1988) · Biochemical Journal · doi:10.1042/bj2550855 · Cited by 135 · see citing works
Cyclic GMP stimulates Na+/Ca2+ exchange in vascular smooth muscle cells in primary culture
Furukawa, K., Ohshima, N., Tawada, Y., & Shigekawa, M. (1991) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)98901-5 · Cited by 134 · see citing works
Kimura, H., Mittal, C. K., & Murad, F. (1975) · Nature · doi:10.1038/257700a0 · Cited by 132 · see citing works
Self-citationInterleukin 1 inhibits contraction of vascular smooth muscle.
Beasley, D., Cohen, R. A., & Levinsky, N. G. (1989) · Journal of Clinical Investigation · doi:10.1172/jci113879 · Cited by 127 · see citing works
Guanosine 3':5'-cyclic monophosphate binding proteins in rat tissues.
Lincoln, T., Hall, C. L., Park, C. R., & Corbin, J. D. (1976) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.73.8.2559 · Cited by 127 · see citing works
Kauffman, R. F., Schenck, K. W., Utterback, B. G., Crowe, V. G., & Cohen, M. L. (1987) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)39185-8 · Cited by 123 · see citing works
Angiotensin II, vasopressin, and sympathetic activity in conscious rats with endotoxemia
Schaller, M. D., Waeber, B., Nussberger, J., & Brunner, H. R. (1985) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.1985.249.6.h1086 · Cited by 113 · see citing works
Fiscus, R. R., Rapoport, R. M., Waldman, S. A., & Murad, F. (1985) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/0167-4889(85)90124-7 · Cited by 110 · see citing works
Self-citationDiminution of contractile response of the aorta from endotoxin-injected rats
Wakabayashi, I., Hatake, K., Kakishita, E., & Nagai, K. (1987) · European Journal of Pharmacology · doi:10.1016/0014-2999(87)90417-1 · Cited by 109 · see citing works
Purification and characterization of 3':5'-cyclic GMP-dependent protein kinase.
Gill, G. N., Holdy, K. E., Walton, G. M., & Kanstein, C. B. (1976) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.73.11.3918 · Cited by 107 · see citing works
Vasodilatation : vascular smooth muscle, peptides, autonomic nerves, and endothelium
Vanhoutte, P. M., & Shepherd, J. T. (1988) · Raven Press eBooks · Cited by 106 · see citing works
Mitchell, J. A., Sheng, H., Förstermann, U., & Murad, F. (1991) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.1991.tb12422.x · Cited by 105 · see citing works
Self-citationCyclic GMP mediates neurogenic relaxation in the bovine retractor penis muscle
Bowman, A., & Drummond, A. H. (1984) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.1984.tb16133.x · Cited by 104 · see citing works
Schini‐Kerth, V. B., Junquero, D. C., Scott‐Burden, T., & Vanhoutte, P. M. (1991) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(91)90897-g · Cited by 104 · see citing works
Nitroxergic nerves mediate vagally induced relaxation in the isolated stomach of the guinea pig.
Desai, K. M., Zembowicz, A., Sessa, W. C., & Vane, J. R. (1991) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.88.24.11490 · Cited by 102 · see citing works
The relaxant effects of atrial natriuretic factor on vascular smooth muscle
Winquist, R. J. (1985) · Life Sciences · doi:10.1016/0024-3205(85)90351-0 · Cited by 97 · see citing works
Dokita, S., Morgan, W. R., Wheeler, M. A., Yoshida, M., Latifpour, J., & Weiss, R. M. (1991) · Life Sciences · doi:10.1016/0024-3205(91)90377-n · Cited by 97 · see citing works
The Membrane Form of Guanylate Cyclase
Thorpe, D. S., & Garbers, D. L. (1989) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)83382-8 · Cited by 96 · see citing works
Effects of nitroprusside and 8-bromo-cyclic GMP on the contractile activity of the rat aorta.
Lincoln, T. (1983) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)33437-3 · Cited by 96 · see citing works
Lower esophageal sphincter relaxation is associated with increased cyclic nucleotide content
Torphy, T. J., Fine, C. F., Burman, M., Barnette, M. S., & Ormsbee, H. S. (1986) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.1986.251.6.g786 · Cited by 94 · see citing works
Contraction and relaxation of the retractor penis muscle and the penile artery of the bull.
Klinge, E., & Sjöstrand, N. O. (1974) · PubMed · Cited by 92 · see citing works
Endothelium inhibits responses of rabbit carotid artery to adrenergic nerve stimulation
Tesfamariam, B., Weisbrod, R. M., & Cohen, R. A. (1987) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.1987.253.4.h792 · Cited by 89 · see citing works
Mollace, V., Salvemini, D., Änggård, E., & Vane, J. R. (1991) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.1991.tb12481.x · Cited by 88 · see citing works
Effects of cGMP on [Ca2+]i, myosin light chain phosphorylation, and contraction in human myometrium
Word, R. A., Casey, M. L., Kamm, K. E., & Stull, J. T. (1991) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.1991.260.4.c861 · Cited by 87 · see citing works
Lincoln, T., Thompson, M. E., & Cornwell, T. L. (1988) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)77883-1 · Cited by 85 · see citing works
Glyceryl trinitrate-induced desensitization of guanylate cyclase in cultured rat lung fibroblasts.
Schröder, H., Leitman, D. C., Bennett, B. M., Waldman, S. A., & Murad, F. (1988) · The Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)22622-2 · Cited by 85 · see citing works
Self-citationCyclic guanosine monophosphate mediates vascular relaxation induced by atrial natriuretic factor.
Ohlstein, E. H., & Berkowitz, B. A. (1985) · Hypertension · doi:10.1161/01.hyp.7.2.306 · Cited by 85 · see citing works
Regional vasorelaxant selectivity of atrial natriuretic factor in isolated rabbit vessels
Faison, E. P., Siegl, P. K. S., Morgan, G. W., & Winquist, R. J. (1985) · Life Sciences · doi:10.1016/0024-3205(85)90599-5 · Cited by 84 · see citing works
In squid axons, ATP modulates Na+-CA2+ exchange by a Cai2+-dependent phosphorylation
DiPolo, R., & Beaugé, L. (1987) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/0005-2736(87)90432-9 · Cited by 78 · see citing works
Silver, P. J., Lepore, R. E., O'Connor, B., Lemp, B. M., Hamel, L. T., Bentley, R. G., & Harris, A. L. (1988) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)20034-9 · Cited by 75 · see citing works
Bennett, B. M., Leitman, D. C., Schröder, H., Kawamoto, J. H., Nakatsu, K., & Murad, F. (1989) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)21364-7 · Cited by 75 · see citing works
Self-citationNeedleman, P., Blehm, D. J., & Rotskoff, K. S. (1969) · PubMed · Cited by 75 · see citing works
Synthetic atrial peptide inhibits intracellular calcium release in smooth muscle
Meisheri, K. D., Taylor, C. J., & Saneii, H. H. (1986) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.1986.250.1.c171 · Cited by 74 · see citing works
Interleukin 1 and endotoxin activate soluble guanylate cyclase in vascular smooth muscle
Beasley, D. (1990) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.1990.259.1.r38 · Cited by 73 · see citing works
Sheng, H., Schmidt, H. H. H. W., Nakane, M., Mitchell, J. A., Pollock, J. S., Föstermann, U., & Murad, F. (1992) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.1992.tb14411.x · Cited by 73 · see citing works
Self-citationFeelisch, M., Noack, E., & Schröder, H. (1988) · European Heart Journal · doi:10.1093/eurheartj/9.suppl_a.57 · Cited by 72 · see citing works
Fink, M. P., HOMER, L. D., & Fletcher, J. R. (1985) · Journal of Surgical Research · doi:10.1016/0022-4804(85)90046-0 · Cited by 72 · see citing works
Nitroprusside enhances isoprenaline-induced increases in cAMP in rat aortic smooth muscle
Maurice, D. H., & Haslam, R. J. (1990) · European Journal of Pharmacology · doi:10.1016/0014-2999(90)94182-w · Cited by 70 · see citing works
Toda, N., Minami, Y., & Okamura, T. (1990) · Life Sciences · doi:10.1016/0024-3205(90)90593-g · Cited by 70 · see citing works
Zhou, H.-L., & Torphy, T. J. (1991) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)20363-9 · Cited by 69 · see citing works
Purification and characterization of particulate guanylate cyclase from sea urchin spermatozoa.
Radany, E. W., Gerzer, R., & Garbers, D. L. (1983) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(20)82071-7 · Cited by 68 · see citing works
Flockerzi, V., Speichermann, N., & Hofmann, F. B. (1978) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)34813-5 · Cited by 67 · see citing works
Sea urchin sperm guanylate cyclase. Purification and loss of cooperativity.
Garbers, D. L. (1976) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)33356-2 · Cited by 66 · see citing works
Oxyhaemoglobin blocks non-adrenergic non-cholinergic inhibition in the bovine retractor penis muscle
Bowman, A., Gillespie, J. S., & Pollock, D. (1982) · European Journal of Pharmacology · doi:10.1016/0014-2999(82)90470-8 · Cited by 64 · see citing works
Jackson, W. F., Mülsch, A., & Busse, R. (1991) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.1991.260.1.h248 · Cited by 64 · see citing works
Lorenz, K. L., & Wells, J. N. (1983) · Molecular Pharmacology · doi:10.1016/s0026-895x(25)14282-x · Cited by 61 · see citing works
Isolation and sequence determination of rat cardiac natriuretic peptide
Kambayashi, Y., Nakao, K., Itoh, H., Hosoda, K., Saito, Y., Yamada, T., Mukoyama, M., Arai, H., Shirakami, G., Suga, S., et al. (1989) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(89)92126-8 · Cited by 61 · see citing works
Endotoxin inhibits contraction of vascular smooth muscle in vitro
Beasley, D., Cohen, R. A., & Levinsky, N. G. (1990) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.1990.258.4.h1187 · Cited by 60 · see citing works
Ives, H. E., CASNELLIE, J. E., Greengard, P., & Jamieson, J. D. (1980) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)85772-1 · Cited by 60 · see citing works
Resink, T. J., Scott‐Burden, T., Baur, U., JONES, C. R., & Bühler, F. R. (1988) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1988.tb13915.x · Cited by 57 · see citing works
Fujii, K., Ishimatsu, T., & Kuriyama, H. (1986) · The Journal of Physiology · doi:10.1113/jphysiol.1986.sp016189 · Cited by 54 · see citing works
Atrial natriuretic factor stimulates Na/K/Cl cotransport in vascular smooth muscle cells.
O’Donnell, M. E., & Owen, N. E. (1986) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.83.16.6132 · Cited by 53 · see citing works
Yeates, R. A., Laufen, H., & Leitold, M. (1985) · Molecular Pharmacology · doi:10.1016/s0026-895x(25)14198-9 · Cited by 53 · see citing works
Release of nitric oxide from human vascular smooth muscle cells
Bernhardt, J., Tschudi, M. R., Dohi, Y., Gut, I. T., Urwyler, B., Bühler, F. R., & Lüscher, T. F. (1991) · Biochemical and Biophysical Research Communications · doi:10.1016/s0006-291x(05)81151-9 · Cited by 52 · see citing works
Budzik, G. P., Firestone, S. L., Bush, E. N., Connolly, P. J., Rockway, T. W., Sarin, V. K., & Holleman, W. H. (1987) · Biochemical and Biophysical Research Communications · doi:10.1016/s0006-291x(87)80527-2 · Cited by 50 · see citing works
Taylor, C. J., & Meisheri, K. D. (1986) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)24850-9 · Cited by 49 · see citing works
Isolation and characterization of iso-rANP, a new natriuretic peptide from rat atria
Flynn, T. G., Brar, A. K., Tremblay, L., Sarda, I. R., Lyons, C., & Jennings, D. B. (1989) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(89)92675-2 · Cited by 46 · see citing works
Needleman, P., Blehm, D. J., & Rotskoff, K. S. (1969) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)28190-3 · Cited by 46 · see citing works
Lindgren, S., Rascón, A., Andersson, K., Manganiello, V. C., & Degerman, E. (1991) · Biochemical Pharmacology · doi:10.1016/0006-2952(91)90317-x · Cited by 44 · see citing works
Greenberg, S. S., DIECKE, F. P. J., Cantor, E. H., Peevy, K. J., & Tanaka, T. P. (1990) · European Journal of Pharmacology · doi:10.1016/0014-2999(90)90368-g · Cited by 43 · see citing works
l ‐Arginine induces relaxation of rat aorta possibly through non‐endothelial nitric oxide formation
Moritoki, H., Ueda, H., Yamamoto, T., Hisayama, T., & Takeuchi, S. (1991) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.1991.tb12263.x · Cited by 39 · see citing works
Drewett, J. G., Trachte, G. J., & Marchand, G. R. (1989) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)23621-7 · Cited by 36 · see citing works
The effects of nitroglycerin on cyclic nucleotides in the coronary artery
Kobayashi, A., Suzuki, Y., Kamikawa, T., Hayashi, H., & Yamazaki, N. (1980) · Life Sciences · doi:10.1016/0024-3205(80)90643-8 · Cited by 36 · see citing works
Lindgren, S., ANDERSSON, T. L. G., Vinge, E., & Andersson, K. (1990) · Acta Physiologica Scandinavica · doi:10.1111/j.1748-1716.1990.tb08993.x · Cited by 36 · see citing works
Ahlner, J., Ljusegren, M. E., Grundström, N., & Axelsson, K. L. (1991) · Circulation Research · doi:10.1161/01.res.68.3.756 · Cited by 35 · see citing works
Tolerance to nitroglycerin is caused by reduced guanylate cyclase activation
Romanin, C. (1989) · Journal of Molecular and Cellular Cardiology · doi:10.1016/0022-2828(89)91491-0 · Cited by 33 · see citing works
Drewett, J. G., Ziegler, R. J., & Trachte, G. J. (1990) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)22924-x · Cited by 31 · see citing works
Neurotransmitter identity doubt
Ignarro, L. J., BUSH, P. A., Buga, G. M., & Rajfer, J. (1990) · Nature · doi:10.1038/347131b0 · Cited by 29 · see citing works
Kawamoto, J. H., McLaughlin, B. E., Brien, J. F., Marks, G. S., & Nakatsu, K. (1990) · Journal of Cardiovascular Pharmacology · doi:10.1097/00005344-199005000-00005 · Cited by 29 · see citing works
Substrates of the cGMP kinase in vascular smooth muscle and their role in the relaxation process
Baltensperger, K., Chiesi, M., & Carafoli, E. (1990) · Biochemistry · doi:10.1021/bi00493a035 · Cited by 28 · see citing works
Mirzazadeh, S., Hobbs, A. J., Tucker, J. F., & Gibson, A. (1991) · Journal of Pharmacy and Pharmacology · doi:10.1111/j.2042-7158.1991.tb06677.x · Cited by 28 · see citing works
Imai, S., Yoshida, Y., & Sun, H.-T. (1990) · The Journal of Biochemistry · doi:10.1093/oxfordjournals.jbchem.a123121 · Cited by 25 · see citing works
Pharmacology and Receptor Binding of Atrial Natriuretic Factor in Vascular Smooth Muscle
Winquist, R. J., Napier, M. A., VANDLEN, R. L., Arcuri, K. E., Keegan, M. E., Faison, E. P., & Baskin, E. P. (1985) · Clinical and Experimental Hypertension · doi:10.3109/10641968509077234 · Cited by 24 · see citing works
Generation of an endothelium-derived relaxing factor-like substance in bovine tracheal smooth muscle
Sheng, H., Ishii, K., & Murad, F. (1991) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.1991.260.6.l489 · Cited by 24 · see citing works
Self-citationSjöstrand, N. O., Eldh, J., SAMUELSON, U. E., Alaranta, S., & Klinge, E. (1990) · Acta Physiologica Scandinavica · doi:10.1111/j.1748-1716.1990.tb09002.x · Cited by 19 · see citing works
Chuprun, J. K., & Rapoport, R. M. (1987) · Cellular and Molecular Life Sciences · doi:10.1007/bf01945566 · Cited by 18 · see citing works
Bowman, A., & McGrath, J. C. (1985) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.1985.tb11086.x · Cited by 17 · see citing works
Dissociation between endothelium-dependent relaxations and increases in cGMP in systemic veins
Vidal, M., Vanhoutte, P. M., & Miller, V. M. (1991) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.1991.260.5.h1531 · Cited by 16 · see citing works
Miwa, K., & Noboru, T. (1985) · The Japanese Journal of Pharmacology · doi:10.1254/jjp.38.313 · Cited by 15 · see citing works
Effect of Nitro-Compound Smooth Muscle Relaxants and Other Materials on Cyclic GMP Metabolism
Murad, F., Mittal, C. K., Arnold, W. P., & Braughler, J. M. (1979) · Elsevier eBooks · doi:10.1016/b978-0-08-023193-8.50016-3 · Cited by 13 · see citing works
Self-citationBaird, A. A., & Muir, T. C. (1990) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.1990.tb15804.x · Cited by 12 · see citing works
Role of cyclic GMP of canine vascular smooth muscle in relaxation by organic nitrates.
Shibata, T., Ogawa, K., Ito, T., Hashimoto, H., Nakagawa, H., & Satake, T. (1986) · Japanese Circulation Journal-english Edition · doi:10.1253/jcj.50.1091 · Cited by 12 · see citing works
Cyclic GMP Modulates Release of Norepinephrine From Adrenergic Nerves Innervating Canine Arteries
Greenberg, S. S., Cantor, E. H., DIECKE, F. P. J., Peevy, K. J., & Tanaka, T. P. (1991) · American Journal of Hypertension · doi:10.1093/ajh/4.2.173 · Cited by 9 · see citing works
Comparative relaxant effects of nitroglycerin in isolated rings from various canine vascular beds
Gharaibeh, M. N., & Gross, G. J. (1984) · General Pharmacology The Vascular System · doi:10.1016/0306-3623(84)90162-9 · Cited by 7 · see citing works
Flagged first, then by citations
4 of the 176 references couldn’t be matched to a known paper.
Cited by
Sorted by citations
Guanylate cyclase and the ⋅NO/cGMP signaling pathway
Denninger, J. W., & Marletta, M. A. (1999) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/s0005-2728(99)00024-9 · Cited by 1,040 · see citing works
cGMP-Dependent Protein Kinases and cGMP Phosphodiesterases in Nitric Oxide and cGMP Action
Francis, S. H., Busch, J. L., & Corbin, J. D. (2010) · Pharmacological Reviews · doi:10.1124/pr.110.002907 · Cited by 1,025 · see citing works
Sources of Vascular Nitric Oxide and Reactive Oxygen Species and Their Regulation
Tejero, J., Shiva, S., & Gladwin, M. T. (2019) · Physiological Reviews · doi:10.1152/physrev.00036.2017 · Cited by 541 · see citing works
Andersson, K., & Wein, A. J. (2004) · Pharmacological Reviews · doi:10.1124/pr.56.4.4 · Cited by 479 · see citing works
Structure and Regulation of Soluble Guanylate Cyclase
Derbyshire, E. R., & Marletta, M. A. (2012) · Annual Review of Biochemistry · doi:10.1146/annurev-biochem-050410-100030 · Cited by 466 · see citing works
Regulation of the Pulmonary Circulation in the Fetus and Newborn
Gao, Y., & Raj, J. U. (2010) · Physiological Reviews · doi:10.1152/physrev.00032.2009 · Cited by 349 · see citing works
Mechanisms for nitric oxide synthesis in plants
Crawford, N. M. (2005) · Journal of Experimental Botany · doi:10.1093/jxb/erj050 · Cited by 333 · see citing works
Lehnert, N., Kim, E., Dong, H. T., Harland, J. B., Hunt, A. P., Manickas, E. C., Oakley, K. M., Pham, J., Reed, G. C., & Alfaro, V. S. (2021) · Chemical Reviews · doi:10.1021/acs.chemrev.1c00253 · Cited by 277 · see citing works
Endothelial function and cardiovascular disease: Effects of quercetin and wine polyphenols
Pérez‐Vizcaíno, F., Duarte, J., & Andriantsitohaina, R. (2006) · Free Radical Research · doi:10.1080/10715760600823128 · Cited by 218 · see citing works
The Role of Nitric Oxide in Cancer: Master Regulator or NOt?
Khan, F. H., Dervan, E., Bhattacharyya, D. D., McAuliffe, J. D., Miranda, K. M., & Glynn, S. A. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21249393 · Cited by 191 · see citing works
Photoreceptor Guanylate Cyclases: A Review
Pugh, E. N., Duda, T., Sitaramayya, A., & Sharma, R. K. (1997) · Bioscience Reports · doi:10.1023/a:1027365520442 · Cited by 169 · see citing works
A nitric oxide/cysteine interaction mediates the activation of soluble guanylate cyclase
Fernhoff, N. B., Derbyshire, E. R., & Marletta, M. A. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0911083106 · Cited by 144 · see citing works
Acceleration of Myosin Light Chain Dephosphorylation and Relaxation of Smooth Muscle by Telokin
Wu, X., Haystead, T., Nakamoto, R. K., Somlyo, A. V., & Somlyo, A. P. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.18.11362 · Cited by 140 · see citing works
Effect of nitric oxide on single skeletal muscle fibres from the mouse
Andrade, F. H., Reid, M. B., Allen, D. G., & Westerblad, H. (1998) · The Journal of Physiology · doi:10.1111/j.1469-7793.1998.577bn.x · Cited by 133 · see citing works
Porphyrins, porphyrin metabolism and porphyrias. I. Update
Thunell, S. (2000) · Scandinavian Journal of Clinical and Laboratory Investigation · doi:10.1080/003655100448310 · Cited by 133 · see citing works
Biochemistry of Soluble Guanylate Cyclase
Derbyshire, E. R., & Marletta, M. A. (2008) · Handbook of experimental pharmacology · doi:10.1007/978-3-540-68964-5_2 · Cited by 130 · see citing works
Qian, Y., Chao, D. S., Santillano, D. R., Cornwell, T. L., Nairn, A. C., Greengard, P., Lincoln, T., & Bredt, D. S. (1996) · Journal of Neuroscience · doi:10.1523/jneurosci.16-10-03130.1996 · Cited by 125 · see citing works
Stones, J. R., & Marletta, M. A. (1998) · Chemistry & Biology · doi:10.1016/s1074-5521(98)90618-4 · Cited by 119 · see citing works
Nitric oxide function in atherosclerosis
Matthys, K. E., & Bult, H. (1997) · Mediators of Inflammation · doi:10.1080/09629359791875 · Cited by 81 · see citing works
Pathophysiology of aged lymphatic vessels
Shang, T., Liang, J., Kapron, C. M., & Liu, J. (2019) · Aging · doi:10.18632/aging.102213 · Cited by 78 · see citing works
Emerging trends in the pathophysiology of lymphatic contractile function
Chakraborty, S., Davis, M. J., & Muthuchamy, M. (2015) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2015.01.005 · Cited by 74 · see citing works
The role of glutamate and nitric oxide in the reproductive neuroendocrine system
Dhandapani, K. M., & Brann, D. W. (2000) · Biochemistry and Cell Biology · doi:10.1139/bcb-78-3-165 · Cited by 69 · see citing works
RELATIONSHIPS BETWEEN THE ENDOTHELIN AND NITRIC OXIDE PATHWAYS
Warner, T. D. (1999) · Clinical and Experimental Pharmacology and Physiology · doi:10.1046/j.1440-1681.1999.03025.x · Cited by 71 · see citing works
Self-citationSoluble guanylate cyclase stimulation: an emerging option in pulmonary hypertension therapy
Ghofrani, H. A., & Grimminger, F. (2009) · European Respiratory Review · doi:10.1183/09059180.00011112 · Cited by 65 · see citing works
Soluble guanylate cyclase gene expression and localization in rat lung after exposure to hypoxia
Li, D., Zhou, N., & Johns, R. A. (1999) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.1999.277.4.l841 · Cited by 63 · see citing works
Redox regulation of soluble guanylyl cyclase
Shah, R. C., Sanker, S., Wood, K. C., Durgin, B. G., & Straub, A. C. (2018) · Nitric Oxide · doi:10.1016/j.niox.2018.03.013 · Cited by 62 · see citing works
Zhang, Y., He, L., Zhang, G., Xu, Y., Lee, O. O., Matsumura, K., & Qian, P. (2012) · Journal of Experimental Biology · doi:10.1242/jeb.070235 · Cited by 59 · see citing works
Kumar, V., Martin, F., Hahn, M. G., Schäfer, M., Stamler, J. S., Stasch, J., & van den Akker, F. (2013) · Biochemistry · doi:10.1021/bi301657w · Cited by 59 · see citing works
Increased soluble guanylate cyclase activity in the red blood cells of sickle cell patients
Conran, N., dos Santos, C. O., Acosta, H. C., Fattori, A., Saad, S. T. O., & Costa, F. F. (2004) · British Journal of Haematology · doi:10.1111/j.1365-2141.2004.04810.x · Cited by 58 · see citing works
Zaborska, K. E., Wareing, M., & Austin, C. E. (2016) · British Journal of Pharmacology · doi:10.1111/bph.13648 · Cited by 51 · see citing works
Nitric oxide and cell signaling; modulation of redox tone and protein modification
Landar, A. L., & Darley-Usmar, V. M. (2003) · Amino Acids · doi:10.1007/s00726-003-0019-7 · Cited by 50 · see citing works
Mediators and mechanisms of relaxation in rabbit urethral smooth muscle
Waldeck, K., Ny, L., Persson, K., & Andersson, K. (1998) · British Journal of Pharmacology · doi:10.1038/sj.bjp.0701645 · Cited by 50 · see citing works
Effect ofCitrus paradisiextract and juice on arterial pressure bothin vitroandin vivo
Díaz-Juárez, J. A., López, F. A. T., Zarco-Olvera, G., del Valle‐Mondragón, L., Torres-Narváez, J. C., & Pastelín-Hernández, G. S. (2009) · Phytotherapy Research · doi:10.1002/ptr.2680 · Cited by 48 · see citing works
Endothelium-independent vasorelaxant effect of sodium ferulate on rat thoracic aorta
Chen, G.-P., Ye, Y., Li, L., Yang, Y., Qian, A.-B., & Hu, S. (2008) · Life Sciences · doi:10.1016/j.lfs.2008.11.003 · Cited by 45 · see citing works
Riociguat: a soluble guanylate cyclase stimulator for the treatment of pulmonary hypertension
Lian, T., Jiang, X., & Jing, Z. (2017) · Drug Design Development and Therapy · doi:10.2147/dddt.s117277 · Cited by 45 · see citing works
Choudhury, N., Khromov, A. S., Somlyo, A. P., & Somlyo, A. V. (2004) · Journal of Muscle Research and Cell Motility · doi:10.1007/s10974-004-7807-x · Cited by 43 · see citing works
Valente, T. S., Baldi, F. S., Sant’Anna, A. C., de Albuquerque, L. G., & da Costa, M. J. R. P. (2016) · PLoS ONE · doi:10.1371/journal.pone.0156956 · Cited by 44 · see citing works
Hennan, J. K., & Diamond, J. (1998) · British Journal of Pharmacology · doi:10.1038/sj.bjp.0701678 · Cited by 43 · see citing works
Nitric oxide and cell death in liver cancer cells
Muntané, J., de la Rosa, Á. J., Gómez, L. M. M., & Ruiz, F. J. P. (2012) · Mitochondrion · doi:10.1016/j.mito.2012.09.004 · Cited by 40 · see citing works
Bae, J., Kumazoe, M., Yamashita, S., & Tachibana, H. (2017) · Scientific Reports · doi:10.1038/s41598-017-06879-5 · Cited by 40 · see citing works
McGrowder, D., Ragoobirsingh, D., & Dasgupta, T. (2001) · Nitric Oxide · doi:10.1006/niox.2001.0360 · Cited by 39 · see citing works
Protein Kinase G-I Deficiency Induces Pulmonary Hypertension through Rho A/Rho Kinase Activation
Zhao, Y. D., Cai, L., Mirza, M. K., Huang, X., Geenen, D. L., Hofmann, F. B., Yuan, J. X. ‐., & Zhao, Y. (2012) · American Journal Of Pathology · doi:10.1016/j.ajpath.2012.02.016 · Cited by 39 · see citing works
Pharmacologic Targets on the Female Urethra
Canda, A. E., Çınar, M., Turna, B., & Şahin, M. O. (2008) · Urologia Internationalis · doi:10.1159/000132690 · Cited by 38 · see citing works
Insight into the Rescue of Oxidized Soluble Guanylate Cyclase by the Activator Cinaciguat
Sürmeli, N. B., & Marletta, M. A. (2012) · ChemBioChem · doi:10.1002/cbic.201100809 · Cited by 36 · see citing works
Derbyshire, E. R., Gunn, A., Ibrahim, M., Spiro, T. G., Britt, R. D., & Marletta, M. A. (2008) · Biochemistry · doi:10.1021/bi7022943 · Cited by 35 · see citing works
Nucleotide Regulation of Soluble Guanylate Cyclase Substrate Specificity
Derbyshire, E. R., Fernhoff, N. B., Deng, S., & Marletta, M. A. (2009) · Biochemistry · doi:10.1021/bi900696x · Cited by 34 · see citing works
MacDonald, J. A., Walker, L. A., Nakamoto, R. K., Gorenne, I., Somlyo, A. V., Somlyo, A. P., & Haystead, T. (2000) · FEBS Letters · doi:10.1016/s0014-5793(00)01884-6 · Cited by 34 · see citing works
Regulation of Sensory Neuron Precursor Proliferation by Cyclic GMP‐Dependent Protein Kinase
Firestein, B. L., & Bredt, D. S. (1998) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.1998.71051846.x · Cited by 34 · see citing works
Identification of an orphan guanylate cyclase receptor selectively expressed in mouse testis
Kühn, M., Ng, C. K. D., Su, Y.-H., Kilić, A., Mitko, D., Bien‐Ly, N., Kömüves, L. G., & Yang, R. (2004) · Biochemical Journal · doi:10.1042/bj20031624 · Cited by 32 · see citing works
Pérez‐Vizcaíno, F., Villamor, E., Duarte, J., & Tamargo, J. L. (1997) · British Journal of Pharmacology · doi:10.1038/sj.bjp.0701257 · Cited by 29 · see citing works
Role of sGC-dependent NO signalling and myocardial infarction risk
Wobst, J., Kessler, T., Dang, T. A., Erdmann, J., & Schunkert, H. (2015) · Journal of Molecular Medicine · doi:10.1007/s00109-015-1265-3 · Cited by 28 · see citing works
The NO signalling pathway in aortic aneurysm and dissection
Toral, M., de la Fuente‐Alonso, A., Campanero, M. R., & Redondo, J. M. (2021) · British Journal of Pharmacology · doi:10.1111/bph.15694 · Cited by 26 · see citing works
Weiss, H. R., Gong, G. X., Straznicka, M., Yan, L., Tse, J., & Scholz, P. M. (1999) · Canadian Journal of Physiology and Pharmacology · doi:10.1139/cjpp-77-6-422 · Cited by 26 · see citing works
Ampey, B. C., Morschauser, T. J., Lampe, P. D., & Magness, R. R. (2014) · Advances in experimental medicine and biology · doi:10.1007/978-1-4939-1031-1_11 · Cited by 24 · see citing works
Soluble guanylyl cyclase during postnatal porcine pulmonary maturation
Moreno, L., González-Luis, G. E., Cogolludo, A. L., Lodi, F., López-Farré, A. J., Tamargo, J. L., Villamor, E., & Pérez‐Vizcaíno, F. (2004) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.00244.2004 · Cited by 24 · see citing works
Aguiar‐Geraldo, J. M., Ferraz, P., & Wallace, J. L. (1996) · Hepatology · doi:10.1002/hep.510230117 · Cited by 24 · see citing works
EFFECT OF cGMP INHIBITORS ON THE ACTIONS OF NITRODILATORS IN RAT AORTA
van der Zypp, A., & Majewski, H. (1998) · Clinical and Experimental Pharmacology and Physiology · doi:10.1111/j.1440-1681.1998.tb02141.x · Cited by 23 · see citing works
NO-GC in cells 'off the beaten track'
Friebe, A., Voußen, B., & Groneberg, D. (2018) · Nitric Oxide · doi:10.1016/j.niox.2018.03.020 · Cited by 22 · see citing works
The design and synthesis of YC-1 analogues as probes for soluble guanylate cyclase
Hering, K. W., Artz, J. D., Pearson, W. H., & Marletta, M. A. (2005) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/j.bmcl.2005.10.093 · Cited by 22 · see citing works
Effects of the Dietary Flavonoid Chrysin in Isolated Rat Mesenteric Vascular Bed
Villar, I. C., Galisteo, M., Vera, R., O’Valle, F., Garcia-Saura, M. F., Zarzuelo, A., & Duarte, J. (2004) · Journal of Vascular Research · doi:10.1159/000081807 · Cited by 21 · see citing works
Time-Dependent Changes of Urethral Function in Diabetes Mellitus: A Review
Cao, N., Gu, B., Gotoh, D., & Yoshimura, N. (2019) · International Neurourology Journal · doi:10.5213/inj.1938050.025 · Cited by 20 · see citing works
Yoshida, Y., Toyosato, A., Islam, M. O., Koga, T., Fujita, S., & Imai, S. (1999) · Molecular and Cellular Biochemistry · doi:10.1023/a:1006991032073 · Cited by 20 · see citing works
Derbyshire, E. R., Deng, S., & Marletta, M. A. (2010) · Journal of Biological Chemistry · doi:10.1074/jbc.m109.098269 · Cited by 19 · see citing works
Alarmones as Vestiges of a Bygone RNA World
Hernández-Morales, R., Becerra, A., & Lazcano, A. (2019) · Journal of Molecular Evolution · doi:10.1007/s00239-018-9883-3 · Cited by 19 · see citing works
Basini, G., Grasselli, F., Ponderato, N., Bussolati, S., & Tamanini, C. (2001) · Reproduction Fertility and Development · doi:10.1071/rd00089 · Cited by 19 · see citing works
Human Soluble Guanylate Cyclase: Functional Expression, Purification and Structural Characterization
Kosarikov, D. N., Young, P., Uversky, V. N., & Gerber, N. C. (2001) · Archives of Biochemistry and Biophysics · doi:10.1006/abbi.2001.2284 · Cited by 18 · see citing works
Pan, J., Yuan, H., Zhang, X., Zhang, H., Xu, Q., Zhou, Y., Tan, L., Nagawa, S., Huang, Z., & Tan, X. (2017) · Scientific Reports · doi:10.1038/srep43112 · Cited by 17 · see citing works
Gender differences in protein kinase G-mediated vasorelaxation of rat aorta
Teede, H. J., van der Zypp, A., & Majewski, H. (2001) · Clinical Science · doi:10.1042/cs1000473 · Cited by 16 · see citing works
Shahin, M. H., Sá, A. C. C., Webb, A., Gong, Y., Langaee, T. Y., McDonough, C. W., Riva, A., Beitleshees, A. L., Chapman, A. B., Gums, J. G., et al. (2017) · Circulation Cardiovascular Genetics · doi:10.1161/circgenetics.116.001404 · Cited by 15 · see citing works
Molecular Variants of Soluble Guanylyl Cyclase Affecting Cardiovascular Risk
Wobst, J., Rumpf, P. M., Dang, T. A., Puimedon, M. S., Erdmann, J., & Schunkert, H. (2015) · Circulation Journal · doi:10.1253/circj.cj-15-0025 · Cited by 15 · see citing works
Effects of Radiation Therapy on Vascular Responsiveness
Lévesque, L., Lam, M., Allaire, P. D., Mondat, M., Houle, S., Beaudoin, G., Donath, D., & Leclerc, G. (2001) · Journal of Cardiovascular Pharmacology · doi:10.1097/00005344-200104000-00005 · Cited by 15 · see citing works
Pérez‐Vizcaíno, F., Cogolludo, A. L., Zaragozá‐Arnáez, F., Fajardo, S., Ibarra, M., López‐López, J. G., & Tamargo, J. L. (1999) · British Journal of Pharmacology · doi:10.1038/sj.bjp.0702924 · Cited by 15 · see citing works
Razavi, M. S., Dixon, J. B., & Gleason, R. L. (2020) · Journal of The Royal Society Interface · doi:10.1098/rsif.2020.0598 · Cited by 13 · see citing works
NO-induced modulation of calcium-oscillations in pulmonary vascular smooth muscle
Pauvert, O., Marthan, R., & Savineau, J. (2000) · Cell Calcium · doi:10.1054/ceca.2000.0123 · Cited by 13 · see citing works
Dou, D., Guo, Y., Lei, Y., Liu, J., Xu, X., Yu, X., & Gao, Y. (2011) · Circulation Journal · doi:10.1253/circj.cj-11-0802 · Cited by 12 · see citing works
Pantan, R., Onsa-Ard, A., Tocharus, J., Wonganan, O., Suksamrarn, A., & Tocharus, C. (2014) · Life Sciences · doi:10.1016/j.lfs.2014.08.010 · Cited by 11 · see citing works
Further characterisation of particulate neuronal nitric oxide synthase in rat small intestine
Geldre, L. A. V., Fraeyman, N., Peeters, T. L., Timmermans, J., & Lefebvre, R. A. (2003) · Autonomic Neuroscience · doi:10.1016/j.autneu.2003.05.001 · Cited by 11 · see citing works
Characterization of a novel cell-surface protein expressed on human sperm
Yang, R., Au, H., Tzeng, C., Tsai, M.-T., Wu, P., Wu, Y.-C., Ling, T., & Huang, Y.-H. (2009) · Human Reproduction · doi:10.1093/humrep/dep359 · Cited by 11 · see citing works
Therapeutic Targeting of the Soluble Guanylate Cyclase
Makrynitsa, G. I., Zompra, A. A., Argyriou, A. I., Spyroulias, G. A., & Topouzis, S. (2019) · Current Medicinal Chemistry · doi:10.2174/0929867326666190108095851 · Cited by 10 · see citing works
NO binds to the distal site of haem in the fully activated soluble guanylate cyclase
Liu, R. R., Kang, Y., & Chen, L. (2023) · Nitric Oxide · doi:10.1016/j.niox.2023.03.002 · Cited by 9 · see citing works
Pan, J., Xu, Q., Lin, Y., Zhong, F., & Tan, X. (2013) · Chemical Communications · doi:10.1039/c3cc43321h · Cited by 9 · see citing works
Zhang, B., Zhang, Z., Ji, H., Shi, H., Chen, S., Yan, D., Jiang, X., & Shi, B. (2017) · Experimental and Therapeutic Medicine · doi:10.3892/etm.2017.5499 · Cited by 9 · see citing works
Inhibitors of PDE1 and PDE5 cGMP phosphodiesterases: patents and therapeutic potential
Sybertz, E. J., & Czarniecki, M. (1997) · Expert Opinion on Therapeutic Patents · doi:10.1517/13543776.7.6.631 · Cited by 9 · see citing works
Khalid, R. R., Maryam, A., Fadouloglou, V. E., Siddiqi, A. R., & Zhang, Y. (2019) · Journal of Molecular Graphics and Modelling · doi:10.1016/j.jmgm.2019.04.009 · Cited by 8 · see citing works
Yoshida, S., Kreger, A. M., & Gittes, G. K. (2023) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2023.1195623 · Cited by 8 · see citing works
Sakai, H., Enzaka, J., Sakai-Oshita, M., Chiba, Y., & Misawa, M. (2010) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2010.06.050 · Cited by 8 · see citing works
Guo, J. X., Yu, X., Liu, Y., Lu, L., Zhu, D., Zhang, Y., Li, L., Zhang, P., Gao, Q., Lu, X., et al. (2022) · Reproductive Toxicology · doi:10.1016/j.reprotox.2022.08.009 · Cited by 7 · see citing works
Probing the Structural Dynamics of the Catalytic Domain of Human Soluble Guanylate Cyclase
Khalid, R. R., Maryam, A., Sezerman, O. U., Mylonas, E., Siddiqi, A. R., & Kokkinidis, M. (2020) · Scientific Reports · doi:10.1038/s41598-020-66310-4 · Cited by 7 · see citing works
González-Luis, G. E., Cogolludo, A. L., Moreno, L., Lodi, F., Tamargo, J. L., Pérez‐Vizcaíno, F., & Villamor, E. (2006) · Neonatology · doi:10.1159/000091968 · Cited by 7 · see citing works
Bae, J., & Park, S.-J. (2024) · Current Issues in Molecular Biology · doi:10.3390/cimb46030154 · Cited by 6 · see citing works
Mumtaz, F., Khan, M. A., Sullivan, M., Thompson, C. S., Mikhailidis, D. P., Morgan, & Dashwood, M. R. (1999) · Endothelium · doi:10.3109/10623329909165307 · Cited by 6 · see citing works
Synthesis and evaluation of a phosphonate analogue of the soluble guanylate cyclase activator YC-1
Martin, N. I., Derbyshire, E. R., & Marletta, M. A. (2007) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/j.bmcl.2007.06.039 · Cited by 6 · see citing works
PHARMACOLOGIC BASIS OF BLADDER AND URETHRAL FUNCTION AND DYSFUNCTION
Andersson, K. (2008) · Elsevier eBooks · doi:10.1016/b978-1-4160-2339-5.50053-7 · Cited by 6 · see citing works
Peinado, V. I., Guitart, M., Blanco, I., Tura-Ceide, O., Paul, T., Barberà, J. A., & Barreiro, E. (2023) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.00258.2022 · Cited by 5 · see citing works
Bae, J., Kumazoe, M., Park, S., Fujimura, Y., & Tachibana, H. (2023) · FEBS Open Bio · doi:10.1002/2211-5463.13708 · Cited by 5 · see citing works
Maprotiline Prevents Monocrotaline-Induced Pulmonary Arterial Hypertension in Rats
Tong, Y., Jiao, Q., Liu, Y., Lv, J., Wang, R., & Zhu, L. (2018) · Frontiers in Pharmacology · doi:10.3389/fphar.2018.01032 · Cited by 5 · see citing works
Structural insights into selective small molecule activation of PKG1α
Metwally, E., Mak, V., Soriano, A., Zebisch, M., Silvestre, H. L., McEwan, P., Ermakov, G., Beaumont, M., Tawa, P., Barker, J. J., et al. (2023) · Communications Biology · doi:10.1038/s42003-023-05095-4 · Cited by 4 · see citing works
Dynamic Modeling and Simulation of Nitric Oxide Gas Delivery to Pulmonary Arterioles
Jeh, H. S., & George, S. C. (2002) · Annals of Biomedical Engineering · doi:10.1114/1.1507327 · Cited by 4 · see citing works
Semyichkina-Glushkovskaia, A., Андреевна, Б. И., Fedosov, I. V., Shirokov, A. A., Tsoy, M. O., Dubrovsky, A. I., Dmitrenko, A. V., Terskov, A. V., Zlatogorskaya, D., Adushkina, V., et al. (2025) · Biomedical Optics Express · doi:10.1364/boe.577347 · Cited by 3 · see citing works
Sakai, H., Hara, T., Todoroki, K., Igarashi, Y., Misawa, M., Narita, M., & Chiba, Y. (2013) · Microvascular Research · doi:10.1016/j.mvr.2013.08.009 · Cited by 3 · see citing works
- Authors
- Warner, T. D., Mitchell, J. A., Sheng, H., & Murad, F.
- Affiliations
- St Bartholomew's Hospital (GB)
- University of California, Los Angeles (US)
- Venue
- Advances in Pharmacology
- Publisher
- Elsevier
- Published
- 1994
- Volume
- 26
- Pages
- 171-194
- ISSN
- 1054-3589 (ISSN-L)
- OpenAlex
- W1437168237
- Cited by
- 117
- References
- 176
- Citations by year
- 2026: 2 · 2025: 2 · 2024: 1 · 2023: 6 · 2022: 1 · 2021: 2 · 2020: 4 · 2019: 5 · 2018: 4 · 2017: 6 · 2016: 2 · 2015: 4 · 2014: 3 · 2013: 3 · 2012: 5
- FWCI
- 3.34
- Type
- book chapter
- Language
- en
- Open access
- closed
- Locations
- Advances in pharmacology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Phosphodiesterase function and regulation
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Receptor Mechanisms and Signaling
- Health Sciences › Medicine › Physiology › Nitric Oxide and Endothelin Effects
- Keywords
- cyclic GMP, smooth muscle relaxation, guanylate cyclase, nitric oxide, atrial natriuretic peptide, smooth muscle tone, second messengers
- MeSH terms
- Animals, Cyclic GMP, Guanylate Cyclase, Humans, Isoenzymes, Muscle Relaxation, Muscle, Smooth
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review