Interaction of the Fanconi Anemia Proteins and BRCA1 in a Common Pathway

The ubiquitin-proteasome proteolytic pathway

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Association of BRCA1 with Rad51 in Mitotic and Meiotic Cells

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RING Finger Proteins

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Brca1 Controls Homology-Directed DNA Repair

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BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures.

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RING fingers mediate ubiquitin-conjugating enzyme (E2)-dependent ubiquitination

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Requirement of ATM-Dependent Phosphorylation of Brca1 in the DNA Damage Response to Double-Strand Breaks

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A family of proteins structurally and functionally related to the E6-AP ubiquitin-protein ligase.

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Ubiquitin-dependent c-Jun degradation in vivo is mediated by the δ domain

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Dynamic changes of BRCA1 subnuclear location and phosphorylation state are initiated by DNA damage

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Loss of Ubr2, an E3 ubiquitin ligase, leads to chromosome fragility and impaired homologous recombinational repair

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Ectopic HOXB4 overcomes the inhibitory effect of tumor necrosis factor-α on Fanconi anemia hematopoietic stem and progenitor cells

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A small ubiquitin binding domain inhibits ubiquitin-dependent protein recruitment to DNA repair foci

Helchowski, C. M., Skow, L., Roberts, K. H., Chute, C. L., & Canman, C. E. (2013) · Cell Cycle · doi:10.4161/cc.26640 · Cited by 28

A novel Leu153Ser mutation of the Fanconi anemia FANCD2 gene is associated with severe chemotherapy toxicity in a pediatric T-cell acute lymphoblastic leukemia

Borriello, A., Locasciulli, A., Bianco, A. M., Criscuolo, M., Conti, V., Grammatico, P., Cappellacci, S., Zatterale, A., Morgese, F., Cucciolla, V., et al. (2006) · Leukemia · doi:10.1038/sj.leu.2404468 · Cited by 27

Fanconi anemia pathway defects in inherited and sporadic cancers.

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Molecular Pathogenesis of Fanconi Anemia

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γ-Irradiation–Induced DNA Damage Checkpoint Activation Involves Feedback Regulation between Extracellular Signal-Regulated Kinase 1/2 and BRCA1

Yan, Y., Black, C. P., Cao, P. T., Haferbier, J. L., Kolb, R. H., Spieker, R. S., Ristow, A. M., & Cowan, K. H. (2008) · Cancer Research · doi:10.1158/0008-5472.can-07-5818 · Cited by 26

3R coordination by Fanconi anemia proteins

Macé‐Aimé, G., Bogliolo, M., Guervilly, J.-H., du Villard, J.-A. D., & Rosselli, F. (2005) · Biochimie · doi:10.1016/j.biochi.2005.05.003 · Cited by 26

Functional analysis of patient-derived mutations in the Fanconi anemia gene, FANCG/XRCC9

Nakanishi, K., Moran, A., Hays, T., Kuang, Y., Fox, E., Garneau, D., Oca, R. M. D., Grompe, M., & D’Andrea, A. D. (2001) · Experimental Hematology · doi:10.1016/s0301-472x(01)00663-4 · Cited by 26

A germline FANCA alteration that is associated with increased sensitivity to DNA damaging agentsPreprint

Wilkes, D. C., Sailer, V., Xue, H., Cheng, H., Collins, C. C., Gleave, M. E., Wang, Y. Z., Demichelis, F., Beltran, H., Rubin, M. A., et al. (2017) · Molecular Case Studies · doi:10.1101/mcs.a001487 · Cited by 26

Towards a Molecular Understanding of the Fanconi Anemia Core Complex

Hodson, C., & Walden, H. (2012) · Anemia · doi:10.1155/2012/926787 · Cited by 27

High Glucose Increases DNA Damage and Elevates the Expression of Multiple DDR Genes

Rahmoon, M. A., Elghaish, R. A., Ibrahim, A. A., Alaswad, Z., Gad, M. Z., El‐Khamisy, S. F., & Elserafy, M. (2023) · Genes · doi:10.3390/genes14010144 · Cited by 25

FANCD2 influences replication fork processes and genome stability in response to clustered DSBs

Zhu, J., Su, F., Mukherjee, S., Mori, E., Hu, B., & Asaithamby, A. (2015) · Cell Cycle · doi:10.1080/15384101.2015.1036210 · Cited by 25

Fanconi anemia proteins interact with CtBP1 and modulate the expression of the Wnt antagonist Dickkopf-1

Huard, C., Tremblay, C. S., Helsper, K., Delisle, M., Schindler, D., Lévesque, G., & Carreau, M. (2013) · Blood · doi:10.1182/blood-2012-02-408997 · Cited by 25

Down-regulated expression of hsa-miR-181c in Fanconi anemia patients: implications in TNFα regulation and proliferation of hematopoietic progenitor cells

Rı́o, P., Agirre, X., Gárate, L., Baños, R., Alvarez, L. A., José‐Eneriz, E. S., Badell, I., Casado, J. A., Garin, M. I., Prósper, F., et al. (2012) · Blood · doi:10.1182/blood-2011-01-331017 · Cited by 25

FANCD2-deficient human fibroblasts are hypersensitive to ionising radiation at oxygen concentrations of 0% and 3% but not under normoxic conditions

Kuhnert, V. M., Kachnic, L. A., Li, L., Purschke, M., Gheorghiu, L., Lee, R., Held, K. D., & Willers, H. (2009) · International Journal of Radiation Biology · doi:10.1080/09553000902883810 · Cited by 25

Snm1B/Apollo functions in the Fanconi anemia pathway in response to DNA interstrand crosslinks

Mason, J. M., & Sekiguchi, J. (2011) · Human Molecular Genetics · doi:10.1093/hmg/ddr153 · Cited by 25

Selection and the Cell Cycle: Positive Darwinian Selection in a Well-Known DNA Damage Response Pathway

O’Connell, M. J. (2010) · Journal of Molecular Evolution · doi:10.1007/s00239-010-9399-y · Cited by 25

Arsenite Binds to the RING Finger Domain of FANCL E3 Ubiquitin Ligase and Inhibits DNA Interstrand Crosslink Repair

Jiang, J., Bellani, M. A., Li, L., Wang, P., Seidman, M. M., & Wang, Y. (2017) · ACS Chemical Biology · doi:10.1021/acschembio.6b01135 · Cited by 25

Inhibition of non-homologous end joining in Fanconi Anemia cells results in rescue of survival after interstrand crosslinks but sensitization to replication associated double-strand breaks

Eccles, L. J., Bell, A., & Powell, S. N. (2018) · DNA repair · doi:10.1016/j.dnarep.2018.02.003 · Cited by 25

BRCA-FA Pathway as a Target for Anti-Tumor Drugs

Flynn, R. L., Gupta, R., Brosh, R. M., & Cantor, S. B. (2008) · Anti-Cancer Agents in Medicinal Chemistry · doi:10.2174/187152008784220285 · Cited by 25

Assessment of FANCD2 nuclear foci formation in paraffin-embedded tumors: a potential patient-enrichment strategy for treatment with DNA interstrand crosslinking agents

Duan, W., Gao, L., Zhao, W., Leon, M. E., Sadée, W., Webb, A., Resnick, K. E., Wu, X., Ramaswamy, B., Cohn, D. E., et al. (2012) · Translational research · doi:10.1016/j.trsl.2012.09.003 · Cited by 24

The PTEN phosphatase functions cooperatively with the Fanconi anemia proteins in DNA crosslink repair

Vuono, E. A., Mukherjee, A., Vierra, D. A., Adroved, M. M., Hodson, C., Deans, A. J., & Howlett, N. G. (2016) · Scientific Reports · doi:10.1038/srep36439 · Cited by 24

K63-linked ubiquitination of FANCG is required for its association with the Rap80-BRCA1 complex to modulate homologous recombination repair of DNA interstand crosslinks

Zhu, B., Yan, K., Li, L., Lin, M., Zhang, S., He, Q., Zheng, D., Yang, H., & Shao, G. (2014) · Oncogene · doi:10.1038/onc.2014.229 · Cited by 25

Ouabain, a Cardiac Glycoside, Inhibits the Fanconi Anemia/BRCA Pathway Activated by DNA Interstrand Cross-Linking Agents

Jun, D. W., Hwang, M., Kim, H. J., Hwang, S. K., Kim, S., & Lee, C. H. (2013) · PLoS ONE · doi:10.1371/journal.pone.0075905 · Cited by 24

FANCD2 mRNA Overexpression is a Bona Fide Indicator of Lymph Node Metastasis in Human Colorectal Cancer

Ozawa, H., Iwatsuki, M., Mimori, K., Sato, T., Johansson, F., Toh, H., Watanabe, M., & Mori, M. (2010) · Annals of Surgical Oncology · doi:10.1245/s10434-010-1002-7 · Cited by 24

A major switch for the Fanconi anemia DNA damage–response pathway

Wang, W. (2008) · Nature Structural & Molecular Biology · doi:10.1038/nsmb1108-1128 · Cited by 24

Biomarkers and Mechanisms of FANCD2 Function

Willers, H., Kachnic, L. A., Luo, C., Li, L., Purschke, M., Borgmann, K., Held, K. D., & Powell, S. N. (2008) · BioMed Research International · doi:10.1155/2008/821529 · Cited by 24

Compromised Fanconi anemia response due to BRCA1 deficiency in cisplatin-sensitive head and neck cancer cell lines

Burkitt, K., & Ljungman, M. E. (2007) · Cancer Letters · doi:10.1016/j.canlet.2007.01.017 · Cited by 24

Dormant origins as a built-in safeguard in eukaryotic DNA replication against genome instability and disease development

Shima, N., & Pederson, K. D. (2017) · DNA repair · doi:10.1016/j.dnarep.2017.06.019 · Cited by 26

Inherited aplastic anaemia

Dokal, I. S. (2003) · The Hematology Journal · doi:10.1038/sj.thj.6200215 · Cited by 24

The involvement of FANCM, FANCI, and checkpoint proteins in the interstrand DNA crosslink repair pathway is conserved in C. elegans

Lee, K. Y., Chung, K. Y., & Koo, H. (2010) · DNA repair · doi:10.1016/j.dnarep.2009.12.018 · Cited by 24

Brca1 in immunoglobulin gene conversion and somatic hypermutation

Longerich, S., Orelli, B. J., Martin, R. W., Bishop, D. K., & Storb, U. (2007) · DNA repair · doi:10.1016/j.dnarep.2007.10.002 · Cited by 24

Quantitative PCR analysis reveals a high incidence of large intragenic deletions in the FANCA gene in Spanish Fanconi anemia patients

Callén, E., Tischkowitz, M. D., Creus, A., Marcos, R., Bueren, J. A., Casado, J. A., Mathew, C. G., & Surrallés, J. (2004) · Cytogenetic and Genome Research · doi:10.1159/000077513 · Cited by 25

Repeated Sequences in CASPASE-5 and FANCD2 but not NF1 Are Targets for Mutation in Microsatellite-Unstable Acute Leukemia/Myelodysplastic Syndrome

Offman, J., Gascoigne, K. E., Bristow, F., Macpherson, P., Bignami, M., Casorelli, I., Leone, G. G. M., Pagano, L., Sica, S., Halil, O., et al. (2005) · Molecular Cancer Research · doi:10.1158/1541-7786.mcr-04-0182 · Cited by 24

Of mice and (wo)men: genotype-phenotype correlations in BRCA1

Hohenstein, P., & Fodde, R. (2003) · Human Molecular Genetics · doi:10.1093/hmg/ddg258 · Cited by 24

The Fanconi Anemia Proteins FANCD2 and FANCJ Interact and Regulate Each Other's Chromatin Localization

Chen, X., Wilson, J. B., McChesney, P. A., Williams, S. A., Kwon, Y., Longerich, S., Marriott, A. S., Sung, P., Jones, N. J., & Kupfer, G. M. (2014) · Journal of Biological Chemistry · doi:10.1074/jbc.m114.552570 · Cited by 24

Lymphocytes of Patients with Alzheimer’s Disease Display Different DNA Damage Repair Kinetics and Expression Profiles of DNA Repair and Stress Response Genes

Leandro, G. D. S., Lôbo, R. R., Oliveira, D. V. N. P., Moriguti, J. C., & Sakamoto‐Hojo, E. T. (2013) · International Journal of Molecular Sciences · doi:10.3390/ijms140612380 · Cited by 23

The chromatin remodeling protein BRG1 modulates BRCA1 response to UV irradiation by regulating ATR/ATM activation

Zhang, L., Chen, H., Gong, M., & Gong, F. (2013) · Frontiers in Oncology · doi:10.3389/fonc.2013.00007 · Cited by 24

Alternative metabolic pathways for energy supply and resistance to apoptosis in Fanconi anaemia

Bogliolo, M. (2002) · Mutagenesis · doi:10.1093/mutage/17.1.25 · Cited by 23

Veliparib Alone or in Combination with Mitomycin C in Patients with Solid Tumors With Functional Deficiency in Homologous Recombination Repair

Villalona-Calero, M. A., Duan, W., Zhao, W., Shilo, K., Schaaf, L. J., Thurmond, J., Westman, J. A., Marshall, J. L., Li, X., Ji, J. J., et al. (2016) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/djv437 · Cited by 23

Melphalan and Exportin 1 Inhibitors Exert Synergistic Antitumor Effects in Preclinical Models of Human Multiple Myeloma

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Several tetratricopeptide repeat (TPR) motifs of FANCG are required for assembly of the BRCA2/D1-D2-G-X3 complex, FANCD2 monoubiquitylation and phleomycin resistance

Wilson, J. B., Blom, E., Cunningham, R., Xiao, Y., Kupfer, G. M., & Jones, N. J. (2010) · Mutation research. Fundamental and molecular mechanisms of mutagenesis · doi:10.1016/j.mrfmmm.2010.04.003 · Cited by 24

Marrow Failure

D’Andrea, A. D., Dahl, N., Guinan, E. C., & Shimamura, A. (2002) · Hematology · doi:10.1182/asheducation-2002.1.58 · Cited by 24

Crystal structure of a Fanconi anemia-associated nuclease homolog bound to 5′ flap DNA: basis of interstrand cross-link repair by FAN1Preprint

Gwon, G. H., Kim, Y., Liu, Y., Watson, A. T., Jo, A., Etheridge, T. J., Yuan, F., Zhang, Y., Kim, Y., Carr, A. M., et al. (2014) · Genes & Development · doi:10.1101/gad.248492.114 · Cited by 23

Fanconi anemia DNA crosslink repair factors protect against LINE-1 retrotransposition during mouse development

Bona, N., & Crossan, G. P. (2023) · Nature Structural & Molecular Biology · doi:10.1038/s41594-023-01067-8 · Cited by 23

Saccharomyces Cerevisiae MHF Complex Structurally Resembles the Histones (H3-H4)2 Heterotetramer and Functions as a Heterotetramer

Yang, H., Zhang, T., Tao, Y., Wu, L., Li, H., Zhou, J., Zhong, C., & Ding, J. (2012) · Structure · doi:10.1016/j.str.2011.12.012 · Cited by 22

Coordinated action of the Fanconi anemia and ataxia telangiectasia pathways in response to oxidative damage

Bosch, P. C., Bogliolo, M., & Surrallés, J. (2011) · DNA repair · doi:10.1016/j.dnarep.2011.02.007 · Cited by 22

Rad18 confers hematopoietic progenitor cell DNA damage tolerance independently of the Fanconi Anemia pathwayin vivo

Yang, Y., Poe, J. C., Yang, L., Fedoriw, A., Desai, S., Magnuson, T., Li, Z., Fedoriw, Y. D., Araki, K., Gao, Y., et al. (2016) · Nucleic Acids Research · doi:10.1093/nar/gkw072 · Cited by 23

Taking a Bad Turn: Compromised DNA Damage Response in Leukemia

Nilles, N., & Fahrenkrog, B. (2017) · Cells · doi:10.3390/cells6020011 · Cited by 22

Loss of homologous recombination or non-homologous end-joining leads to radial formation following DNA interstrand crosslink damage

Newell, A. E. H., Hemphill, A., Akkari, Y. M. N., Hejna, J., Moses, R. E., & Olson, S. B. (2008) · Cytogenetic and Genome Research · doi:10.1159/000138882 · Cited by 22

The Fanconi anemia protein interaction network: Casting a wide net

Rego, M. A., Kolling, F. W., & Howlett, N. G. (2008) · Mutation research. Fundamental and molecular mechanisms of mutagenesis · doi:10.1016/j.mrfmmm.2008.11.018 · Cited by 22

The Fanconi Anemia/BRCA Pathway

Bogliolo, M., & Surrallés, J. (2006) · Springer eBooks · doi:10.1007/0-387-36802-7_6 · Cited by 22

The Caenorhabditis elegans FancD2 ortholog is required for survival following DNA damage

Dequen, F., St-Laurent, J.-F., Gagnon, S., Carreau, M., & Desnoyers, S. (2005) · Comparative Biochemistry and Physiology Part B Biochemistry and Molecular Biology · doi:10.1016/j.cbpc.2005.05.010 · Cited by 22

FBW7 regulates DNA interstrand cross-link repair by modulating FAAP20 degradation

Wang, J., Jo, U., Joo, S. Y., & Kim, H. (2016) · Oncotarget · doi:10.18632/oncotarget.9595 · Cited by 21

Fanconi anemia protein FANCD2 inhibits TRF1 polyADP-ribosylation through tankyrase1-dependent manner

Lyakhovich, A., Ramírez, M. J., Castellanos‐Martín, A., Castellà, M., Simons, A. M., Parvin, J. D., & Surrallés, J. (2011) · Genome Integrity · doi:10.1186/2041-9414-2-4 · Cited by 23

Telomeric DNA induces p53-dependent reactive oxygen species and protects against oxidative damage

Lee, M. S., Yaar, M., Eller, M. S., Rünger, T. M., Gao, Y. J., & Gilchrest, B. A. (2009) · Journal of Dermatological Science · doi:10.1016/j.jdermsci.2009.08.008 · Cited by 21

Fanconi anemia D2 protein confers chemoresistance in response to the anticancer agent, irofulven

Wang, Y., Wiltshire, T. D., Senft, J., Wenger, S. L., Reed, E., & Wang, W. (2006) · Molecular Cancer Therapeutics · doi:10.1158/1535-7163.mct-06-0427 · Cited by 21

Fatal Lymphoproliferative Disease in Two Siblings Lacking Functional FAAP24

Daschkey, S., Bienemann, K., Schuster, V. H., Kreth, H. W., Linka, R. M., Hönscheid, A., Fritz, G., Johannes, C., Fleckenstein, B., Kempkes, B., et al. (2016) · Journal of Clinical Immunology · doi:10.1007/s10875-016-0317-y · Cited by 21

Targeting Homologous Recombination Repair in Cancer

Willers, H., Pfäffle, H. N., & Zou, L. (2011) · Elsevier eBooks · doi:10.1016/b978-0-12-384999-1.10007-1 · Cited by 21

Phosphorylation of Fanconi Anemia Protein, FANCA, Is Regulated by Akt Kinase

Otsuki, T., Nagashima, T., Komatsu, N., Kirito, K., Furukawa, Y., Kobayashi, S., Liu, J. M., & Ozawa, K. (2002) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.2002.6504 · Cited by 21

Frequency of Fanconi anemia in Brazil and efficacy of screening for the FANCA 3788-3790del mutation

Magdalena, N., Pilonetto, D., Bitencourt, M. A., Pereira, N. F., Ribeiro, R. C., Jeng, M., & Pasqüini, R. (2005) · Brazilian Journal of Medical and Biological Research · doi:10.1590/s0100-879x2005000500003 · Cited by 21

Expression and prognostic significance of Fanconi anemia group D2 protein and breast cancer type 1 susceptibility protein in familial and sporadic breast cancer

Liang, F., & Jin, F. (2019) · Oncology Letters · doi:10.3892/ol.2019.10046 · Cited by 20

FANC Pathway Promotes UV-Induced Stalled Replication Forks Recovery by Acting Both Upstream and Downstream Polη and Rev1

Renaud, E., & Rosselli, F. (2013) · PLoS ONE · doi:10.1371/journal.pone.0053693 · Cited by 20

Patient-derived C-terminal mutation of FANCI causes protein mislocalization and reveals putative EDGE motif function in DNA repair

Colnaghi, L., Jones, M. V., Cotto-Rios, X. M., Schindler, D., Hanenberg, H., & Huang, T. T. (2010) · Blood · doi:10.1182/blood-2010-07-295758 · Cited by 20

Discrete Nonparametric Algorithms for Outlier Detection with Genomic Data

Ghosh, D. (2010) · Journal of Biopharmaceutical Statistics · doi:10.1080/10543400903572704 · Cited by 20

Targeting the Fanconi Anemia Pathway to Identify Tailored Anticancer Therapeutics

Jenkins, C., Kan, J., & Hoatlin, M. E. (2012) · Anemia · doi:10.1155/2012/481583 · Cited by 20

Activation of the FA pathway mediated by phosphorylation and ubiquitination

Ishiai, M., Sato, K., Tomida, J., Kitao, H., Kurumizaka, H., & Takata, M. (2017) · Mutation research. Fundamental and molecular mechanisms of mutagenesis · doi:10.1016/j.mrfmmm.2017.05.003 · Cited by 20

Evolutionary Clues to the Molecular Function of Fanconi Anemia Genes

Blom, E., van de Vrugt, H. J., de Winter, J. P., Arwert, F., & Joenje, H. (2002) · Acta Haematologica · doi:10.1159/000065659 · Cited by 20

Characterization, expression and complex formation of the murine Fanconi anaemia gene product Fancg

van de Vrugt, H. J., Koomen, M., Berns, M. A. D., de Vries, Y., Rooimans, M. A., van der Weel, L., Blom, E., de Groot, J., Schepers, R. J., Stone, S., et al. (2002) · Genes to Cells · doi:10.1046/j.1365-2443.2002.00518.x · Cited by 20

Fanconi anaemia: from a monogenic disease to sporadic cancer

Valeri, A., Martinez, S. L., Casado, J. A., & Bueren, J. A. (2011) · Clinical & Translational Oncology · doi:10.1007/s12094-011-0645-6 · Cited by 19

Disrupted Signaling through the Fanconi Anemia Pathway Leads to Dysfunctional Hematopoietic Stem Cell Biology: Underlying Mechanisms and Potential Therapeutic Strategies

Geiselhart, A., Lier, A., Walter, D., & Milsom, M. D. (2012) · Anemia · doi:10.1155/2012/265790 · Cited by 19

Chronic treatment with cisplatin induces chemoresistance through the TIP60-mediated Fanconi anemia and homologous recombination repair pathways

Su, W., Ho, Y.-C., Wu, C.-K., Hsu, S.-H., Shiu, J.-L., Huang, J.-C., Chang, S., Chiu, W., Hung, J., Liu, T.-L., et al. (2017) · Scientific Reports · doi:10.1038/s41598-017-04223-5 · Cited by 19

Compromised repair of radiation-induced DNA double-strand breaks in Fanconi anemia fibroblasts in G2

Zahnreich, S., Weber, B., Rösch, G., Schindler, D., & Schmidberger, H. (2020) · DNA repair · doi:10.1016/j.dnarep.2020.102992 · Cited by 21

The Fanconi anemia ubiquitin E3 ligase complex as an anti-cancer target

Sharp, M. F., Bythell‐Douglas, R., Deans, A. J., & Crismani, W. (2021) · Molecular Cell · doi:10.1016/j.molcel.2021.04.023 · Cited by 20

Regulation of the Fanconi Anemia Group C Protein through Proteolytic Modification

Brodeur, I., Goulet, I., Tremblay, C. S., Charbonneau, C., Delisle, M., Godin, C., Huard, C., Khandjian, E. W., Buchwald, M., Lévesque, G., et al. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m301291200 · Cited by 19

Increased sensitivity of Fancc-deficient hematopoietic cells to nitric oxide and evidence that this species mediates growth inhibition by cytokines

Hadjur, S., & Jirik, F. R. (2003) · Blood · doi:10.1182/blood-2002-10-3147 · Cited by 19

A cytoplasmic serine protein kinase binds and may regulate the Fanconi anemia protein FANCA

Yagasaki, H., Adachi, D., Oda, T., García-Higuera, I., Tetteh, N., D’Andrea, A. D., Futaki, M., Asano, S., & Yamashita, T. (2001) · Blood · doi:10.1182/blood.v98.13.3650 · Cited by 19

FANCD2 limits acetaldehyde‐induced genomic instability during DNA replication in esophageal keratinocytes

Peake, J. D., Noguchi, C., Lin, B., Theriault, A., O'Connor, M. H., Sheth, S., Tanaka, K., Nakagawa, H., & Noguchi, E. (2021) · Molecular Oncology · doi:10.1002/1878-0261.13072 · Cited by 19

Human LINE-1 retrotransposons: impacts on the genome and regulation by host factors

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The Fanconi anemia pathway: Insights from somatic cell genetics using DT40 cell line

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Coordinate Nuclear Targeting of the FANCD2 and FANCI Proteins via a FANCD2 Nuclear Localization Signal

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SCAI promotes error‐free repair of DNA interstrand crosslinks via the Fanconi anemia pathway

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Topo IIIα and BLM Act within the Fanconi Anemia Pathway in Response to DNA-Crosslinking Agents

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The ubiquitin family meets the Fanconi anemia proteins

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FANCD2 deficiency sensitizes SHH medulloblastoma to radiotherapy via ferroptosis

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FANCJ protein is important for the stability of FANCD2/FANCI proteins and protects them from proteasome and caspase-3 dependent degradation

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BRCA1 Is Required for Maintenance of Phospho-Chk1 and G2/M Arrest during DNA Cross-Link Repair in DT40 Cells

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Fanconi anemia‐like presentation in an infant with constitutional deletion of 21q including the RUNX1 gene

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FANCD2 is a target for caspase 3 during DNA damage‐induced apoptosis

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Fanconi anemia complementation group A (FANCA) localizes to centrosomes and functions in the maintenance of centrosome integrity

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S-phase–specific interaction of the Fanconi anemia protein, FANCD2, with BRCA1 and RAD51

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Functional Interaction of Monoubiquitinated FANCD2 and BRCA2/FANCD1 in Chromatin

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