Interaction of the Fanconi Anemia Proteins and BRCA1 in a Common Pathway

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A novel cell‐free screen identifies a potent inhibitor of the Fanconi anemia pathway

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Amplification and translocation of 3q26 with overexpression of EVI1 in Fanconi anemia‐derived childhood acute myeloid leukemia with biallelic FANCD1/BRCA2 disruption

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Mechanistic link between DNA damage sensing, repairing and signaling factors and immune signaling

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The Fanconi anemia gene network is conserved from zebrafish to human

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The Fanconi Anemia Signalosome Anchor

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An Inverse Switch in DNA Base Excision and Strand Break Repair Contributes to Melphalan Resistance in Multiple Myeloma Cells

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C. elegans: A model of Fanconi anemia and ICL repair

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The Effects of the Fanconi Anemia Zinc Finger (FAZF) on Cell Cycle, Apoptosis, and Proliferation Are Differentiation Stage-specific

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High levels of RAD51 perturb DNA replication elongation and cause unscheduled origin firing due to impaired CHK1 activation

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Cracking the Monoubiquitin Code of Genetic Diseases

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Helq acts in parallel to Fancc to suppress replication-associated genome instability

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Translational regulation of the mRNA encoding the ubiquitin peptidase USP1 involved in the DNA damage response as a determinant of Cisplatin resistance

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CtIP Is Required to Initiate Replication-Dependent Interstrand Crosslink Repair

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UBR2 of the N-End Rule Pathway Is Required for Chromosome Stability via Histone Ubiquitylation in Spermatocytes and Somatic Cells

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Ubiquitination-Linked Phosphorylation of the FANCI S/TQ Cluster Contributes to Activation of the Fanconi Anemia I/D2 Complex

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Selective Killing of Cancer Cells by Nonplanar Aromatic Hydrocarbon‐Induced DNA Damage

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Regulation of the activation of the Fanconi anemia pathway by the p21 cyclin-dependent kinase inhibitor

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FANCJ Helicase Operates in the Fanconi Anemia DNA Repair Pathway and the Response to Replicational Stress

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DNA Repair Protein Biomarkers Associated with Time to Recurrence in Triple-Negative Breast Cancer

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Cell resistance to the Cytolethal Distending Toxin involves an association of DNA repair mechanisms

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Spectrum ofFANCA mutations in Italian Fanconi anemia patients: Identification of six novel alleles and phenotypic characterization of the S858R variant

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The Fanconi anemia group C gene product

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The Fanconi anemia ID2 complex: Dueling saxes at the crossroads

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Rescue of replication failure by Fanconi anaemia proteins

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A requirement of FancL and FancD2 monoubiquitination in DNA repair

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Fanconi Anemia: Causes and Consequences of Genetic Instability

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A case report and literature review of Fanconi Anemia (FA) diagnosed by genetic testing

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BRCA1—A good predictive marker of drug sensitivity in breast cancer treatment?

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Fanconi Anemia pathway heterogeneity revealed by cisplatin and oxaliplatin treatments

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FANCD2 protein is expressed in proliferating cells of human tissues that are cancer‐prone in Fanconi anaemia

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Post-Translational Modification of Cellular Proteins by Ubiquitin and Ubiquitin-Like Molecules: Role in Cellular Senescence and Aging

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Overabundant FANCD2, alone and combined with NQO1, is a sensitive marker of adverse prognosis in breast cancer

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The Fanconi anemia/BRCA gene network in zebrafish: Embryonic expression and comparative genomics

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Current Knowledge on the Pathophysiology of Fanconi Anemia: From Genes to Phenotypes

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Identification of multiple nuclear export sequences in Fanconi anemia group A protein that contribute to CRM1-dependent nuclear export

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The Two Faces of BRCA2, a FANCtastic Discovery

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Spectrum of sequence variation in theFANCG gene: An International Fanconi Anemia Registry (IFAR) study

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Alcohol Induces DNA Damage and the Fanconi Anemia D2 Protein Implicating FANCD2 in the DNA Damage Response Pathways in Brain

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Can the response to a platinum-based therapy be predicted by the DNA repair status in non-small cell lung cancer?

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FANCD2 Confers a Malignant Phenotype in Esophageal Squamous Cell Carcinoma by Regulating Cell Cycle Progression

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Normal lymphocyte development and thymic lymphoma formation in Brca1 exon-11-deficient mice

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Interstrand crosslink-induced radials form between non-homologous chromosomes, but are absent in sex chromosomes

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The neglected members of the family: non-BRCAmutations in the Fanconi anemia/BRCA pathway and reproduction

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The Fanconi anemia pathway in replication stress and DNA crosslink repair

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Small-Molecule Inhibition of UBE2T/FANCL-Mediated Ubiquitylation in the Fanconi Anemia Pathway

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The DNA-damage kinase ATR activates the FANCD2-FANCI clamp by priming it for ubiquitination

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Myeloid lineage‐selective growth of revertant cells in Fanconi anaemia

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Regulation of the Fanconi anemia pathway by a CUE ubiquitin-binding domain in the FANCD2 protein

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ALPK2 is crucial for luminal apoptosis and DNA repair-related gene expression in a three-dimensional colonic-crypt model.

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Comprehensive review of genetic factors contributing to head and neck squamous cell carcinoma development in low‐risk, nontraditional patients

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Chemosensitizing tumor cells by targeting the Fanconi anemia pathway with an adenovirus overexpressing dominant-negative FANCA

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Deficient Regulation of DNA Double-strand Break Repair in Fanconi Anemia Fibroblasts

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Inherited bone marrow failure syndromes in 2012

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Constitutive role of the Fanconi anemia D2 gene in the replication stress response

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PARP inhibition and synthetic lethality in ovarian cancer

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Celastrol induces proteasomal degradation of FANCD 2 to sensitize lung cancer cells to DNA crosslinking agents

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Mitotic DNA Synthesis Is Differentially Regulated between Cancer and Noncancerous Cells

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The Fanconi Family Adds a Fraternal Twin

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Co-opting the Fanconi Anemia Genomic Stability Pathway Enables Herpesvirus DNA Synthesis and Productive Growth

Karttunen, H., Savas, J. N., McKinney, C. C., Chen, Y.-H., Yates, J. R., Hukkanen, V., Huang, T. T., & Mohr, I. (2014) · Molecular Cell · doi:10.1016/j.molcel.2014.05.020 · Cited by 30

Specificity for deubiquitination of monoubiquitinated FANCD2 is driven by the N-terminus of USP1

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Fanconi Anemia Complementation Group A (FANCA) Protein Has Intrinsic Affinity for Nucleic Acids with Preference for Single-stranded Forms

Yuan, F., Qian, L., Zhao, X., Liu, J. Y., Song, L., D’Urso, G., Jain, C., & Zhang, Y. (2011) · Journal of Biological Chemistry · doi:10.1074/jbc.m111.315366 · Cited by 30

FANCJ/BRIP1 recruitment and regulation of FANCD2 in DNA damage responses

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Genetic profile ofGNAQ-mutated blue melanocytic neoplasms reveals mutations in genes linked to genomic instability and the PI3K pathway

Pérez‐Alea, M., Vivancos, A. P., Caratù, G., Matito, J., Fábrega, B. F., Hernández‐Losa, J., Cortés, J., Muñoz‐Couselo, E., García‐Patos, V., & Recio, J. A. (2016) · Oncotarget · doi:10.18632/oncotarget.8578 · Cited by 30

Defects in homologous recombination repair behind the human diseases: FA and HBOC

Katsuki, Y., & Takata, M. (2016) · Endocrine Related Cancer · doi:10.1530/erc-16-0221 · Cited by 32

A distinct role for recombination repair factors in an early cellular response to transcription–replication conflicts

Shao, X., Joergensen, A. M., Howlett, N. G., Lisby, M., & Oestergaard, V. H. (2020) · Nucleic Acids Research · doi:10.1093/nar/gkaa268 · Cited by 36

A new nuclease member of the FAN club

Huang, M., & D'Andrea, A. D. (2010) · Nature Structural & Molecular Biology · doi:10.1038/nsmb0810-926 · Cited by 29

Overnight transduction with foamyviral vectors restores the long-term repopulating activity of Fancc−/− stem cells

Si, Y. C., Pulliam, A. C., Linka, Y., Ciccone, S. L. M., Leurs, C., Yuan, J., Eckermann, O., Früehauf, S., Mooney, S. D., Hanenberg, H., et al. (2008) · Blood · doi:10.1182/blood-2007-07-102947 · Cited by 29

A concomitant loss of dormant origins and FANCC exacerbates genome instability by impairing DNA replication fork progression

Luebben, S. W., Kawabata, T., Johnson, C. S., O’Sullivan, M. G., & Shima, N. (2014) · Nucleic Acids Research · doi:10.1093/nar/gku170 · Cited by 29

The Fanconi Anemia DNA Repair Pathway Is Regulated by an Interaction between Ubiquitin and the E2-like Fold Domain of FANCL

Miles, J. A., Frost, M. G., Carroll, E., Rowe, M. L., Howard, M. J., Sidhu, A., Chaugule, V. K., Alpi, A. F., & Walden, H. (2015) · Journal of Biological Chemistry · doi:10.1074/jbc.m115.675835 · Cited by 29

Bone Marrow Transplantation for Inherited Bone Marrow Failure Syndromes

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High-risk human papillomavirus oncogenes disrupt the Fanconi anemia DNA repair pathway by impairing localization and de-ubiquitination of FancD2

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The BRUCE‐ATR Signaling Axis Is Required for Accurate DNA Replication and Suppression of Liver Cancer Development

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Impaired Type I IFN-Induced Jak/STAT Signaling in FA-C Cells and Abnormal CD4+ Th Cell Subsets in Fancc−/− Mice

Fagerlie, S. R., Koretsky, T., Torok‐Storb, B., & Bagby, G. C. (2004) · The Journal of Immunology · doi:10.4049/jimmunol.173.6.3863 · Cited by 30

Telomere dynamics in Fancg-deficient mouse and human cells

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The carboxyl-terminal of BRCA1 is required for subnuclear assembly of RAD51 after treatment with cisplatin but not ionizing radiation in human breast and ovarian cancer cells

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Overexpressed thioredoxin compensates Fanconi anemia related chromosomal instability

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The Fanconi anemia pathway promotes DNA glycosylase‐dependent excision of interstrand DNA crosslinks

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Rad18 is required for functional interactions between FANCD2, BRCA2, and Rad51 to repair DNA topoisomerase 1-poisons induced lesions and promote fork recovery

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Clinical importance of FANCD2, BRIP1, BRCA1, BRCA2 and FANCF expression in ovarian carcinomas

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Motifs of the C-terminal domain of MCM9 direct localization to sites of mitomycin-C damage for RAD51 recruitment

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UBE2W Interacts with FANCL and Regulates the Monoubiquitination of Fanconi Anemia Protein FANCD2

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A cross‐linker‐sensitive myeloid leukemia cell line from a 2‐year‐old boy with severe Fanconi anemia and biallelic FANCD1/BRCA2 mutations

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The Fanconi anemia pathway and the DNA interstrand cross-links repair

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Human Mus81 and FANCB independently contribute to repair of DNA damage during replication

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Disease model: Fanconi anemia

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ZNF365 Promotes Stability of Fragile Sites and Telomeres

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Fanconi anemia and homologous recombination gene variants are associated with functional DNA repair defects in vitro and poor outcome in patients with advanced head and neck squamous cell carcinoma

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HSF2BP negatively regulates homologous recombination in DNA interstrand crosslink repair

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Bcr/Abl Interferes with the Fanconi Anemia/BRCA Pathway: Implications in the Chromosomal Instability of Chronic Myeloid Leukemia Cells

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Allosteric mechanism for site-specific ubiquitination of FANCD2

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Cigarette smoke induces genetic instability in airway epithelial cells by suppressing FANCD2 expression

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ATR–Chk1 signaling pathway and homologous recombinational repair protect cells from 5-fluorouracil cytotoxicity

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The nuclear accumulation of the Fanconi anemia protein FANCE depends on FANCC

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Phosphorylation of the Menin Tumor Suppressor Protein on Serine 543 and Serine 583

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Fanconi anemia protein complex is a novel target of the IKK signalsome

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Fanconi anemia FANCD2 and FANCI proteins regulate the nuclear dynamics of splicing factors

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A new look at molecular biology of breast cancer

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Regulation of cellular responses by deubiquitinating enzymes: an update

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Function of the Fanconi anemia pathway in Fanconi anemia complementation group F and D1 cells

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S-phase–specific interaction of the Fanconi anemia protein, FANCD2, with BRCA1 and RAD51

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Functional Interaction of Monoubiquitinated FANCD2 and BRCA2/FANCD1 in Chromatin

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