Laboratory diagnosis of invasive aspergillosis

Hope, WW; Walsh, TJ; Denning, DW

doi:10.1016/s1473-3099(05)70238-3

Cited by 495Antifungal resistance and susceptibilityFungal and yeast genetics researchFungal Infections and Studies

Laboratory diagnosis of invasive aspergillosis

Open access

Hope, WW, Walsh, TJ, Denning, DW·2005·The Lancet Infectious Diseases

DOI 10.1016/s1473-3099(05)70238-3

Open this paper in CoChat — free account

Abstract

Invasive aspergillosis occurs in a wide range of clinical scenarios, is protean in its manifestations, and is still associated with an unacceptably high mortality rate. Early diagnosis is critical to a favourable outcome, but is difficult to achieve with current methods. Deep tissue diagnostic specimens are often difficult to obtain from critically ill patients. Newer antifungal agents exhibit differential mould activity, thus increasing the importance of establishing a specific diagnosis of invasive aspergillosis. For these reasons, a range of alternate diagnostic strategies have been investigated. Most investigative efforts have focused on molecular and serological diagnostic techniques. The detection of metabolites produced by Aspergillus spp and a range of aspergillus-specific antibodies represent additional, but relatively underused, diagnostic avenues. The detection of galactomannan has been incorporated into diagnostic criteria for invasive aspergillosis, reflecting an increased understanding of the performance, utility, and limitations of this technique. Measurement of (1,3)-beta-D glucan in blood may be useful as a preliminary screening tool for invasive aspergillosis, despite the fact that this antigen can be detected in a number of other fungi. There have been extensive efforts directed toward the detection of Aspergillus spp DNA, but a lack of technical standardisation and relatively poor understanding of DNA release and kinetics continues to hamper the broad applicability of this technique. This review considers the application, utility, and limitations of the currently available and investigational diagnostic modalities for invasive aspergillosis.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1016/s1473-3099(05)70238-3

Cites

135 of 135 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Conventional microscopy and culture of respiratory tract sample has only low sensitivity and specificity of around 50%.
“conventional microscopy and culture of respiratory tract sample has only low sensitivity and specificity of around 50%.57”
From Co-infections in people with COVID-19: a systematic review and meta-analysis. (2020) · cites this paper as [57]

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Manual of Clinical Microbiology.
(1980) · Annals of Internal Medicine · doi:10.7326/0003-4819-93-6-939_2 · Cited by 14,435 · see citing works
Voriconazole versus Amphotericin B for Primary Therapy of Invasive Aspergillosis
Herbrecht, R., Denning, D. W., Patterson, T. F., Bennett, J. E., Greene, R. E., Oestmann, J.-W., Kern, W. V., Marr, K. A., Ribaud, P., Lortholary, O., et al. (2002) · New England Journal of Medicine · doi:10.1056/nejmoa020191 · Cited by 3,304 · see citing works
Self-citation
Manual of clinical microbiology
Drasar, B. (2003) · Transactions of the Royal Society of Tropical Medicine and Hygiene · doi:10.1016/s0035-9203(03)90074-5 · Cited by 2,605 · see citing works
Defining Opportunistic Invasive Fungal Infections in Immunocompromised Patients with Cancer and Hematopoietic Stem Cell Transplants: An International Consensus
Aşçıoğlu, S., Rex, J. H., de Pauw, B., Bennett, J. E., Billé, J., Crokaert, F., Denning, D. W., Donnelly, J. P., Edwards, J. E., Erjavec, Z., et al. (2002) · Clinical Infectious Diseases · doi:10.1086/323335 · Cited by 2,315 · see citing works
Self-citation
Aspergillus fumigatus and Aspergillosis
Latgé, J.-P. (1999) · Clinical Microbiology Reviews · doi:10.1128/cmr.12.2.310 · Cited by 2,307 · see citing works
Atlas of Clinical Fungi
de Hoog, S., Guarro, J., Gené, J., & Figueras, M. J. (2000) · UvA-DARE (University of Amsterdam) · Cited by 1,427 · see citing works
Genomic sequence of the pathogenic and allergenic filamentous fungus Aspergillus fumigatus
Nierman, W. C., Pain, A., Anderson, M. J., Wortman, J. R., Kim, H. S., Arroyo, J., Berriman, M., Abe, K., Archer, D. B., Bermejo, C., et al. (2005) · Nature · doi:10.1038/nature04332 · Cited by 1,391 · see citing works
Self-citation
Bronchoalveolar lavage
Mitchell, D., Wells, A. U., Spiro, S. G., & Moller, D. (2012) · CRC Press eBooks · doi:10.1201/b13322-18 · Cited by 828 · see citing works
Epidemiology ofAspergillusInfections in a Large Cohort of Patients Undergoing Bone Marrow Transplantation
Wald, A., Leisenring, W., van Burik, J., & Bowden, R. A. (1997) · The Journal of Infectious Diseases · doi:10.1086/516480 · Cited by 742 · see citing works
-D-Glucan as a Diagnostic Adjunct for Invasive Fungal Infections: Validation, Cutoff Development, and Performance in Patients with Acute Myelogenous Leukemia and Myelodysplastic Syndrome
Odabaşı, Z., Mattiuzzi, G. N., Estey, E., Kantarjian, H. M., Saeki, F., Ridge, R. J., Ketchum, P. A., Finkelman, M., Rex, J. H., & Ostrosky‐Zeichner, L. (2004) · Clinical Infectious Diseases · doi:10.1086/421944 · Cited by 641 · see citing works
Identification of common Aspergillus species
Klich, M. A. (2002) · Medical Entomology and Zoology · Cited by 626 · see citing works
Detection and identification of fungal pathogens in blood by using molecular probes
Einsele, H., Hebart, H. F., Roller, G., Löffler, J., Rothenhöfer, I., Müller, C. A., Bowden, R. A., van Burik, J., Engelhard, D., Kanz, L., et al. (1997) · Journal of Clinical Microbiology · doi:10.1128/jcm.35.6.1353-1360.1997 · Cited by 580 · see citing works
Chronic Cavitary and Fibrosing Pulmonary and Pleural Aspergillosis: Case Series, Proposed Nomenclature Change, and Review
Denning, D. W., Riniotis, K., Dobrashian, R., & Sambatakou, H. (2003) · Clinical Infectious Diseases · doi:10.1086/376526 · Cited by 551 · see citing works
Self-citation
Invasive aspergillosis in critically ill patients without malignancy
Meersseman, W., Vandecasteele, S. J., Wilmer, A., Verbeken, E., Peetermans, W. E., & Van Wijngaerden, E. (2004) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200401-093oc · Cited by 547 · see citing works
Plasma (1→3)-β-D-glucan measurement in diagnosis of invasive deep mycosis and fungal febrile episodes
Obayashi, T., Kawai, T., Yoshida, M., Mori, T., Goto, H., Yasuoka, A., Shimada, K., Iwasaki, H., Teshima, H., KOHNO, S., et al. (1995) · The Lancet · doi:10.1016/s0140-6736(95)91152-9 · Cited by 530 · see citing works
Screening for circulating galactomannan as a noninvasive diagnostic tool for invasive aspergillosis in prolonged neutropenic patients and stem cell transplantation recipients: a prospective validation
Maertens, J. A., Verhaegen, J., Lagrou, K., Eldere, J. V., & Boogaerts, M. (2001) · Blood · doi:10.1182/blood.v97.6.1604 · Cited by 513 · see citing works
Detection of circulating galactomannan for the diagnosis and management of invasive aspergillosis
Mennink‐Kersten, M. A. S. H., Donnelly, J. P., & Verweij, P. E. (2004) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(04)01045-x · Cited by 482 · see citing works
Detection of Galactomannan Antigenemia by Enzyme Immunoassay for the Diagnosis of Invasive Aspergillosis: Variables That Affect Performance
Marr, K. A., Balajee, S. A., McLaughlin, L., Tabouret, M., Bentsen, C. G., & Walsh, T. J. (2004) · The Journal of Infectious Diseases · doi:10.1086/422009 · Cited by 481 · see citing works
Self-citation
Antifungal Therapy Decreases Sensitivity of theAspergillus Galactomannan Enzyme Immunoassay
Marr, K. A., Laverdière, M., Gugel, A., & Leisenring, W. M. (2005) · Clinical Infectious Diseases · doi:10.1086/429921 · Cited by 473 · see citing works
A Stain for Fungi in Tissue Sections and Smears
Grocott, R. G. (1955) · American Journal of Clinical Pathology · doi:10.1093/ajcp/25.8_ts.0975 · Cited by 462 · see citing works
The Impact of Culture Isolation ofAspergillusSpecies: A Hospital‐Based Survey of Aspergillosis
Perfect, J. R., Cox, G. M., Lee, J. Y., Kauffman, C. A., de Repentigny, L., Chapman, S. W., Morrison, V. A., Pappas, P., Hiemenz, J. W., Stevens, D. A., et al. (2001) · Clinical Infectious Diseases · doi:10.1086/323900 · Cited by 458 · see citing works
Rapid Identification of Fungi by Using the ITS2 Genetic Region and an Automated Fluorescent Capillary Electrophoresis System
Turenne, C. Y., Sanche, S. E., Hoban, D. J., Karlowsky, J. A., & Kabani, A. M. (1999) · Journal of Clinical Microbiology · doi:10.1128/jcm.37.6.1846-1851.1999 · Cited by 435 · see citing works
AspergillusGalactomannan Detection in the Diagnosis of Invasive Aspergillosis in Cancer Patients
Herbrecht, R., Letscher‐Bru, V., Oprea, C., Lioure, B., Waller, J., Campos, F., Villard, O., Liu, K.-L., Natarajan‐Amé, S., Lutz, P., et al. (2002) · Journal of Clinical Oncology · doi:10.1200/jco.2002.07.004 · Cited by 391 · see citing works
Bronchoalveolar Lavage
Crystal, R. G., Reynolds, H. Y., & Kalica, A. R. (1986) · CHEST Journal · doi:10.1378/chest.90.1.122 · Cited by 390 · see citing works
Autopsy-Controlled Prospective Evaluation of Serial Screening for Circulating Galactomannan by a Sandwich Enzyme-Linked Immunosorbent Assay for Hematological Patients at Risk for Invasive Aspergillosis
Maertens, J. A., Verhaegen, J., Demuynck, H., Brock, P. R., Verhoef, G. E. G., Vandenberghe, P., Eldere, J. V., VERBIST, L., & Boogaerts, M. (1999) · Journal of Clinical Microbiology · doi:10.1128/jcm.37.10.3223-3228.1999 · Cited by 376 · see citing works
Identification of Aspergillus Species Using Internal Transcribed Spacer Regions 1 and 2
Henry, T. J., Iwen, P. C., & Hinrichs, S. H. (2000) · Journal of Clinical Microbiology · doi:10.1128/jcm.38.4.1510-1515.2000 · Cited by 373 · see citing works
Pulmonary Aspergillosis: Early Diagnosis Improves Survival
von Eiff, M., Roos, N., Schulten, R., Hesse, M., Zühlsdorf, M., & van de Loo, J. (2009) · Respiration · doi:10.1159/000196477 · Cited by 351 · see citing works
Use of Circulating Galactomannan Screening for Early Diagnosis of Invasive Aspergillosis in Allogeneic Stem Cell Transplant Recipients
Maertens, J. A., Eldere, J. V., Verhaegen, J., Verbeken, E. K., Verschakelen, J., & Boogaerts, M. (2002) · The Journal of Infectious Diseases · doi:10.1086/343804 · Cited by 343 · see citing works
Contribution of (1→3)-β- d -Glucan Chromogenic Assay to Diagnosis and Therapeutic Monitoring of Invasive Aspergillosis in Neutropenic Adult Patients: a Comparison with Serial Screening for Circulating Galactomannan
Pazos, C., Pontón, J., & del Palacio, A. (2005) · Journal of Clinical Microbiology · doi:10.1128/jcm.43.1.299-305.2005 · Cited by 335 · see citing works
A new sensitive sandwich enzyme-linked immunosorbent assay to detect galactofuran in patients with invasive aspergillosis
Stynen, D., Goris, A., Sarfati, J., & Latgé, J. P. (1995) · Journal of Clinical Microbiology · doi:10.1128/jcm.33.2.497-500.1995 · Cited by 330 · see citing works
The use of respiratory-tract cultures in the diagnosis of invasive pulmonary aspergillosis
Horvath, J. A., & Dummer, S. J. (1996) · The American Journal of Medicine · doi:10.1016/s0002-9343(97)89455-7 · Cited by 323 · see citing works
Chemical and immunological characterization of the extracellular galactomannan of Aspergillus fumigatus
Latgé, J. P., Kobayashi, H., Debeaupuis, J. P., Diaquin, M., Sarfati, J., Wieruszeski, J. M., Parra, E., Bouchara, J. P., & Fournet, B. (1994) · Infection and Immunity · doi:10.1128/iai.62.12.5424-5433.1994 · Cited by 319 · see citing works
Rapid Identification of Pathogenic Fungi Directly from Cultures by Using Multiplex PCR
Luo, G., & Mitchell, T. G. (2002) · Journal of Clinical Microbiology · doi:10.1128/jcm.40.8.2860-2865.2002 · Cited by 297 · see citing works
Infections Due to Aspergillus terreus: A Multicenter Retrospective Analysis of 83 Cases
Steinbach, W. J., Benjamin, D. K., Kontoyiannis, D. P., Perfect, J. R., Lutsar, I., Marr, K. A., Lionakis, M. S., Torres, H. A., Jafri, H. S., & Walsh, T. J. (2004) · Clinical Infectious Diseases · doi:10.1086/421950 · Cited by 294 · see citing works
Self-citation
AspergillusGalactomannan Enzyme Immunoassay and Quantitative PCR for Diagnosis of Invasive Aspergillosis with Bronchoalveolar Lavage Fluid
Musher, B., Fredricks, D. N., Leisenring, W. M., Balajee, S. A., Smith, C. A., & Marr, K. A. (2004) · Journal of Clinical Microbiology · doi:10.1128/jcm.42.12.5517-5522.2004 · Cited by 283 · see citing works
Significance of isolation of aspergillus from the respiratory tract in diagnosis of invasive pulmonary aspergillosis. Results from a three-year prospective study
Yu, V. L., Muder, R. R., & Poorsattar, A. (1986) · The American Journal of Medicine · doi:10.1016/0002-9343(86)90259-7 · Cited by 280 · see citing works
Aspergillus nidulans Infection in Chronic Granulomatous Disease
Segal, B. H., DeCarlo, E. S., Kwon-Chung, K. J., Malech, H. L., Gallin, J. I., & Holland, S. M. (1998) · Medicine · doi:10.1097/00005792-199809000-00004 · Cited by 263 · see citing works
Experimental Pulmonary Aspergillosis Due toAspergillus terreus:Pathogenesis and Treatment of an Emerging Fungal Pathogen Resistant to Amphotericin B
Walsh, T. J., Petraitis, V., Petraitienė, R., Field‐Ridley, A., Sutton, D. A., Ghannoum, M. A., Sein, T., Schaufele, R. L., Peter, J., Bacher, J. D., et al. (2003) · The Journal of Infectious Diseases · doi:10.1086/377210 · Cited by 252 · see citing works
Self-citation
False‐Positive Galactomannan PlateliaAspergillusTest Results for Patients Receiving Piperacillin‐Tazobactam
Viscoli, C., Machetti, M., Cappellano, P., Bucci, B., Bruzzi, P., Lint, M. T. V., & Bacigalupo, A. P. (2004) · Clinical Infectious Diseases · doi:10.1086/382224 · Cited by 244 · see citing works
Use of Real‐Time PCR on Blood Samples for Diagnosis of Invasive Aspergillosis
Kami, M., Fukui, T., Ogawa, S., Kazuyama, Y., Machida, U., Tanaka, Y., Kanda, Y., Kashima, T., Yamazaki, Y., Hamaki, T., et al. (2001) · Clinical Infectious Diseases · doi:10.1086/323337 · Cited by 243 · see citing works
Diagnosis of Invasive Septate Mold Infections
Tarrand, J. J., Lichterfeld, M. D., Warraich, I. I., Luna, M. A., Han, X. Y., May, G. S., & Kontoyiannis, D. P. (2003) · American Journal of Clinical Pathology · doi:10.1309/exbvyaupenbm285y · Cited by 238 · see citing works
False Positive Test for Aspergillus Antigenemia Related to Concomitant Administration of Piperacillin and Tazobactam
Sulahian, A., Touratier, S., & Ribaud, P. (2003) · New England Journal of Medicine · doi:10.1056/nejm200312113492424 · Cited by 237 · see citing works
Specificity of a sandwich enzyme-linked immunosorbent assay for detecting Aspergillus galactomannan
Swanink, C. M. A., Meis, J. F. G. M., Rijs, A. J. M. M., Donnelly, J. P., & Verweij, P. E. (1997) · Journal of Clinical Microbiology · doi:10.1128/jcm.35.1.257-260.1997 · Cited by 222 · see citing works
Galactomannan detection in computerized tomography‐based broncho‐alveolar lavage fluid and serum in haematological patients at risk for invasive pulmonary aspergillosis
Becker, M. J., Lugtenburg, E. J., Cornelissen, J. J., van der Schee, C., Hoogsteden, H. C., & de Marie, S. (2003) · British Journal of Haematology · doi:10.1046/j.1365-2141.2003.04308.x · Cited by 216 · see citing works
Quantitative PCR Assay To Measure Aspergillus fumigatus Burden in a Murine Model of Disseminated Aspergillosis: Demonstration of Efficacy of Caspofungin Acetate
Bowman, J. C., Abruzzo, G. K., Anderson, J. W., Flattery, A. M., Gill, C. J., Pikounis, V. B., Schmatz, D. M., Liberator, P., & Douglas, C. M. (2001) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.45.12.3474-3481.2001 · Cited by 208 · see citing works
Comparison of Serum Galactomannan Antigen Detection and Competitive Polymerase Chain Reaction for Diagnosing Invasive Aspergillosis
Bretagne, S., Costa, J., Bart–Delabesse, E., Dhédin, N., Rieux, C., & Cordonnier, C. (1998) · Clinical Infectious Diseases · doi:10.1086/516343 · Cited by 207 · see citing works
Plasma (1-->3)-beta-D-glucan and fungal antigenemia in patients with candidemia, aspergillosis, and cryptococcosis
Miyazaki, T., KOHNO, S., Mitsutake, K., Maesaki, S., Tanaka, K., Ishikawa, N., & Hara, K. (1995) · Journal of Clinical Microbiology · doi:10.1128/jcm.33.12.3115-3118.1995 · Cited by 204 · see citing works
Prospective Assessment of Platelia™Aspergillus Galactomannan Antigen for the Diagnosis of Invasive Aspergillosis in Lung Transplant Recipients
Husain, S., Kwak, E. J., Obman, A., Wagener, M. M., Kusne, S., Stout, J. E., McCurry, K. R., & Singh, N. (2004) · American Journal of Transplantation · doi:10.1111/j.1600-6143.2004.00415.x · Cited by 199 · see citing works
British Society for Medical Mycology proposed standards of care for patients with invasive fungal infections
Denning, D. W., Kibbler, C. C., & Barnes, R. A. (2003) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(03)00580-2 · Cited by 194 · see citing works
Self-citation
Late onset of invasive aspergillus infection in bone marrow transplant patients at a university hospital
Grow, W., Moreb, J., Roque, D. R., Manion, K., Leather, H. L., Reddy, V. S., Khan, S., Finiewicz, K. J., Hà, N. H., Cj, C., et al. (2002) · Bone Marrow Transplantation · doi:10.1038/sj.bmt.1703332 · Cited by 192 · see citing works
Sandwich enzyme-linked immunosorbent assay compared with Pastorex latex agglutination test for diagnosing invasive aspergillosis in immunocompromised patients
Verweij, P. E., Stynen, D., Rijs, A. J. M. M., Pauw, B. E. D., Hoogkamp-Korstanje, J. A. A., & Meis, J. F. G. M. (1995) · Journal of Clinical Microbiology · doi:10.1128/jcm.33.7.1912-1914.1995 · Cited by 191 · see citing works
General primer-mediated PCR for detection of Aspergillus species
Melchers, W. J. G., Verweij, P. E., van den Hurk, P., van Belkum, A., Pauw, B. E. D., Hoogkamp-Korstanje, J. A. A., & Meis, J. F. G. M. (1994) · Journal of Clinical Microbiology · doi:10.1128/jcm.32.7.1710-1717.1994 · Cited by 190 · see citing works
Early Detection ofAspergillusInfection after Allogeneic Stem Cell Transplantation by Polymerase Chain Reaction Screening
Hebart, H. F., Löffler, J., Meisner, C., Serey, F., Schmidt, D., Böhme, A., Martin, H., Engel, A., Bunje, D., Kern, W. V., et al. (2000) · The Journal of Infectious Diseases · doi:10.1086/315435 · Cited by 189 · see citing works
Detection of Aspergillus species DNA in bronchoalveolar lavage samples by competitive PCR
Bretagne, S., Costa, J., Marmorat‐Khuong, A., Poron, F., Cordonnier, C., Vidaud, M., & Fleury‐Feith, J. (1995) · Journal of Clinical Microbiology · doi:10.1128/jcm.33.5.1164-1168.1995 · Cited by 188 · see citing works
Progress in the Diagnosis and Management of Aspergillosis in Bone Marrow Transplantation: 13 Years' Experience
McWhinney, P. H. M., Kibbler, C. C., Hamon, M. D., Smith, O. P., Gandhi, L., Berger, L. A., Walesby, R. K., Hoffbrand, A. V., & Prentice, H. G. (1993) · Clinical Infectious Diseases · doi:10.1093/clinids/17.3.397 · Cited by 186 · see citing works
Efficacy of Unilamellar Liposomal Amphotericin B in Treatment of Pulmonary Aspergillosis in Persistently Granulocytopenic Rabbits: The Potential Role of Bronchoalveolar D-Mannitol and Serum Galactomannan as Markers of Infection
Francis, P., Lee, J. W., Hoffman, A. G. D., Peter, J., Francesconi, A., Bacher, J., Shelhamer, J. H., Pizzo, P. A., & Walsh, T. J. (1994) · The Journal of Infectious Diseases · doi:10.1093/infdis/169.2.356 · Cited by 185 · see citing works
Self-citation
The Role of Bronchoalveolar Lavage in the Diagnosis of Invasive Pulmonary Aspergillosis
Kahn, F. W., Jones, J. M., & England, D. M. (1986) · American Journal of Clinical Pathology · doi:10.1093/ajcp/86.4.518 · Cited by 184 · see citing works
Real-Time PCR Coupled with Automated DNA Extraction and Detection of Galactomannan Antigen in Serum by Enzyme-Linked Immunosorbent Assay for Diagnosis of Invasive Aspergillosis
Costa, C., Costa, J., Desterke, C., Botterel, F., Cordonnier, C., & Bretagne, S. (2002) · Journal of Clinical Microbiology · doi:10.1128/jcm.40.6.2224-2227.2002 · Cited by 183 · see citing works
Utility of Aspergillus Antigen Detection in Specimens Other than Serum Specimens
Klont, R. R., Mennink‐Kersten, M. A. S. H., & Verweij, P. E. (2004) · Clinical Infectious Diseases · doi:10.1086/425317 · Cited by 182 · see citing works
Invasive Aspergillosis in Allogeneic Stem Cell Transplant Recipients: Increasing Antigenemia Is Associated with Progressive Disease
Boutboul, F., Alberti, C., Leblanc, T. M., Sulahian, A., Gluckman, É., Derouin, F., & Ribaud, P. (2002) · Clinical Infectious Diseases · doi:10.1086/339324 · Cited by 178 · see citing works
Detection of Gliotoxin in Experimental and Human Aspergillosis
Lewis, R. E., Wiederhold, N. P., Chi, J., Han, X. Y., Komanduri, K. V., Kontoyiannis, D. P., & Prince, R. A. (2004) · Infection and Immunity · doi:10.1128/iai.73.1.635-637.2005 · Cited by 175 · see citing works
Comparison of different methods for extraction of DNA of fungal pathogens from cultures and blood
Löffler, J., Hebart, H. F., Schumacher, U., Reitze, H., & Einsele, H. (1997) · Journal of Clinical Microbiology · doi:10.1128/jcm.35.12.3311-3312.1997 · Cited by 172 · see citing works
Prospective clinical evaluation of lower cut‐offs for galactomannan detection in adult neutropenic cancer patients and haematological stem cell transplant recipients
Maertens, J. A., Theunissen, K., Verbeken, E. K., Lagrou, K., Verhaegen, J., Boogaerts, M., & Eldere, J. V. (2004) · British Journal of Haematology · doi:10.1111/j.1365-2141.2004.05140.x · Cited by 169 · see citing works
Contaminations Occurring in Fungal PCR Assays
Loeffler, J., Hebart, H. F., Bialek, R., Hagmeyer, L., Schmidt, D., Serey, F., Hartmann, M., Eucker, J., & Einsele, H. (1999) · Journal of Clinical Microbiology · doi:10.1128/jcm.37.4.1200-1202.1999 · Cited by 160 · see citing works
Rapid Extraction of Genomic DNA from Medically Important Yeasts and Filamentous Fungi by High-Speed Cell Disruption
Müller, F. C., Werner, K. E., Kasai, M., Francesconi, A., Chanock, S. J., & Walsh, T. J. (1998) · Journal of Clinical Microbiology · doi:10.1128/jcm.36.6.1625-1629.1998 · Cited by 156 · see citing works
Self-citation
The value of bronchoalveolar lavage and bronchial washings in the diagnosis of invasive pulmonary aspergillosis
Levy, H. A., Horak, D. A., Tegtmeier, B., Yokota, S. B., & Forman, S. J. (1992) · Respiratory Medicine · doi:10.1016/s0954-6111(06)80062-4 · Cited by 153 · see citing works
Invasive aspergillosis. Absence of detectable antibody response.
Young, R. C., & Bennett, J. (1971) · PubMed · doi:10.1164/arrd.1971.104.5.710 · Cited by 153 · see citing works
Detection of Aspergillus galactomannan antigen in foods and antibiotics
Ansorg, R., Boom, R. V. D., & Rath, P. (1997) · Mycoses · doi:10.1111/j.1439-0507.1997.tb00249.x · Cited by 152 · see citing works
Detection of Galactomannan Antigenemia in Patients Receiving Piperacillin-Tazobactam and Correlations between In Vitro, In Vivo, and Clinical Properties of the Drug-Antigen Interaction
Walsh, T. J., Shoham, S., Petraitienė, R., Sein, T., Schaufele, R. L., Kelaher, A. M., Murray, H., Mya-San, C., Bacher, J. D., & Petraitis, V. (2004) · Journal of Clinical Microbiology · doi:10.1128/jcm.42.10.4744-4748.2004 · Cited by 151 · see citing works
Self-citation
Detection of Aspergillus fumigatus by polymerase chain reaction
Spreadbury, C. L., Holden, D. W., Aufauvre‐Brown, A., Bainbridge, B. W., & Cohen, J. (1993) · Journal of Clinical Microbiology · doi:10.1128/jcm.31.3.615-621.1993 · Cited by 151 · see citing works
Comparison of Real-Time PCR, Conventional PCR, and Galactomannan Antigen Detection by Enzyme-Linked Immunosorbent Assay Using Bronchoalveolar Lavage Fluid Samples from Hematology Patients for Diagnosis of Invasive Pulmonary Aspergillosis
Sanguinetti, M., Posteraro, B., Pagano, L., Pagliari, G., Fianchi, L., Mele, L., Sorda, M. L., Franco, A., & Fadda, G. M. (2003) · Journal of Clinical Microbiology · doi:10.1128/jcm.41.8.3922-3925.2003 · Cited by 150 · see citing works
In Situ Hybridization for the Differentiation of Aspergillus, Fusarium, and Pseudallescheria Species in Tissue Section
Hayden, R. T., Isotalo, P. A., Parrett, T., Wolk, D. M., Qian, X., Roberts, G. D., & Lloyd, R. V. (2003) · Diagnostic Molecular Pathology · doi:10.1097/00019606-200303000-00003 · Cited by 145 · see citing works
PCR and single-strand conformational polymorphism for recognition of medically important opportunistic fungi
Walsh, T. J., Francesconi, A., Kasai, M., & Chanock, S. J. (1995) · Journal of Clinical Microbiology · doi:10.1128/jcm.33.12.3216-3220.1995 · Cited by 142 · see citing works
Self-citation
Efficacy of Galactomannan Antigen in the Platelia Aspergillus Enzyme Immunoassay for Diagnosis of Invasive Aspergillosis in Liver Transplant Recipients
Kwak, E. J., Husain, S., Obman, A., Meinke, L., Stout, J. E., Kusne, S., Wagener, M. M., & Singh, N. (2004) · Journal of Clinical Microbiology · doi:10.1128/jcm.42.1.435-438.2004 · Cited by 141 · see citing works
A review of nucleic acid-based diagnostic tests for systemic mycoses with an emphasis on polymerase chain reaction-based assays
Chen, S. C. ‐., Halliday, C. L., & Meyer, W. (2002) · Medical Mycology · doi:10.1080/mmy.40.4.333.357 · Cited by 135 · see citing works
Role of fiberoptic bronchoscopy in the diagnosis of invasive pulmonary aspergillosis in patients with acute leukemia
Albelda, S. Μ., Talbot, G. H., Gerson, S. L., Miller, W. T., & Cassileth, P. A. (1984) · The American Journal of Medicine · doi:10.1016/0002-9343(84)90853-2 · Cited by 134 · see citing works
Detection and differentiation of fungi in clinical specimens using polymerase chain reaction (PCR) amplification and restriction enzyme analysis
Hopfer, R. L., Walden, P., Setterquist, S., & Highsmith, W. E. (1993) · Medical Mycology · doi:10.1080/02681219380000071 · Cited by 134 · see citing works
Serum Aspergillus galactomannan antigen testing by sandwich ELISA: Practical use in neutropenic patients
Bretagne, S., Marmorat‐Khuong, A., Kuentz, M., Latgé, J., Bart–Delabesse, E., & Cordonnier, C. (1997) · Journal of Infection · doi:10.1016/s0163-4453(97)90833-1 · Cited by 129 · see citing works
Aspergillus terreus
Hachem, R. Y., Kontoyiannis, D. P., Boktour, M. R., Afif, C., Cooksley, C. D., Bodey, G. P., Chatzinikolaou, I., Perego, C., Kantarjian, H. M., & RAAD, I. I. (2004) · Cancer · doi:10.1002/cncr.20554 · Cited by 128 · see citing works
Anticoagulants Interfere with PCR Used To Diagnose Invasive Aspergillosis
García, M. E., Blanco, J. L., Caballero, J., & Gargallo‐Viola, D. (2002) · Journal of Clinical Microbiology · doi:10.1128/jcm.40.4.1567-1568.2002 · Cited by 123 · see citing works
Development of a LightCycler PCR Assay for Detection and Quantification ofAspergillus fumigatusDNA in Clinical Samples from Neutropenic Patients
Spieß, B., Buchheidt, D., Baust, C., Skladny, H., Seifarth, W., Zeilfelder, U., Leib‐Mösch, C., Mörz, H., & Hehlmann, R. (2003) · Journal of Clinical Microbiology · doi:10.1128/jcm.41.5.1811-1818.2003 · Cited by 123 · see citing works
Panfungal PCR and Multiplex Liquid Hybridization for Detection of Fungi in Tissue Specimens
Hendolin, P., Paulin, L. G., Koukila-Kähkölä, P., Anttila, V., Malmberg, H., Richardson, M. D., & Ylikoski, J. S. (2000) · Journal of Clinical Microbiology · doi:10.1128/jcm.38.11.4186-4192.2000 · Cited by 123 · see citing works
Bifidobacterium lipoteichoic acid and false ELISA reactivity in aspergillus antigen detection
Mennink-Kersten, M. A., Klont, R. R., Warris, A., Op den Camp, H. J., & Verweij, P. E. (2004) · The Lancet · doi:10.1016/s0140-6736(03)15393-7 · Cited by 121 · see citing works
Nucleic Acid Sequence-Based Amplification of Aspergillus RNA in Blood Samples
Loeffler, J., Hebart, H. F., Cox, P., Flues, N., Schumacher, U., & Einsele, H. (2001) · Journal of Clinical Microbiology · doi:10.1128/jcm.39.4.1626-1629.2001 · Cited by 118 · see citing works
Comparison between Plasma and Whole Blood Specimens for Detection of Aspergillus DNA by PCR
Loeffler, J., Hebart, H. F., Brauchle, U., Schumacher, U., & Einsele, H. (2000) · Journal of Clinical Microbiology · doi:10.1128/jcm.38.10.3830-3833.2000 · Cited by 117 · see citing works
ASPERGILLUS ANTIGENEMIA SANDWICH-ENZYME IMMUNOASSAY TEST AS A SERODIAGNOSTIC METHOD FOR INVASIVE ASPERGILLOSIS IN LIVER TRANSPLANT RECIPIENTS1
Fortün, J., Martín‐Dávila, P., Alvarez, M. E., Sánchez-Sousa, A., Quereda, C., Navas, E., Bárcena, R., Vicente, E., Candelas, A., Honrubia, A., et al. (2001) · Transplantation · doi:10.1097/00007890-200101150-00023 · Cited by 112 · see citing works
Failure To Detect Circulating Aspergillus Markers in a Patient with Chronic Granulomatous Disease and Invasive Aspergillosis
Verweij, P. E., Weemaes, C. M. R., Curfs, J. H. A. J., Bretagne, S., & Meis, J. F. G. M. (2000) · Journal of Clinical Microbiology · doi:10.1128/jcm.38.10.3900-3901.2000 · Cited by 111 · see citing works
Airways Inflammation, Atopy, and (1 → 3)- β - d -Glucan Exposures in Two Schools
Rylander, R., Norrhall, M., ENGDAHL, U., Tunsäter, A., & Holt, P. G. (1998) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.158.5.9712139 · Cited by 108 · see citing works
Development of a PCR-Based Line Probe Assay for Identification of Fungal Pathogens
Martin, C. M., Roberts, D., van der Weide, M., Rossau, R., Jannes, G., Smith, T., & Maher, M. (2000) · Journal of Clinical Microbiology · doi:10.1128/jcm.38.10.3735-3742.2000 · Cited by 98 · see citing works
New cause for false-positive results with the Pastorex Aspergillus antigen latex agglutination test
Kappe, R., & Schulze‐Berge, A. (1993) · Journal of Clinical Microbiology · doi:10.1128/jcm.31.9.2489-2490.1993 · Cited by 96 · see citing works
Prediction of invasive pulmonary aspergillosis from colonisation of lower respiratory tract before marrow transplantation
Einsele, H., Quabeck, K., Müller, K.-D., Hebart, H. F., Rothenhöfer, I., Löffler, J., & Schaefer, U. (1998) · The Lancet · doi:10.1016/s0140-6736(05)61265-2 · Cited by 86 · see citing works
False‐positive results in premature infants with the Platelia®Aspergillus sandwich enzyme‐linked immunosorbent assay
Siemann, M., Koch‐Dörfler, M., & Gaude, M. (1998) · Mycoses · doi:10.1111/j.1439-0507.1998.tb00356.x · Cited by 86 · see citing works
Molecular diagnostics in clinical parasitology and mycology: limits of the current polymerase chain reaction (PCR) assays and interest of the real-time PCR assays
Bretagne, S. (2003) · Clinical Microbiology and Infection · doi:10.1046/j.1469-0691.2003.00677.x · Cited by 82 · see citing works
Detection and Identification of Fungi from Fungus Balls of the Maxillary Sinus by Molecular Techniques
Willinger, B., Obradovic, A., Selitsch, B., Beck‐Mannagetta, J., Buzina, W., Braun, H., Apfalter, P., Hirschl, A. M., Makristathis, A., & Rotter, M. L. (2003) · Journal of Clinical Microbiology · doi:10.1128/jcm.41.2.581-585.2003 · Cited by 82 · see citing works
Reactivity of Platelia Aspergillus Galactomannan Antigen with Piperacillin-Tazobactam: Clinical Implications Based on Achievable Concentrations in Serum
Singh, N., Obman, A., Husain, S., Aspinall, S. L., Mietzner, S. M., & Stout, J. E. (2004) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.48.6.1989-1992.2004 · Cited by 81 · see citing works
Immunohistologic identification of Aspergillus spp. and other hyaline fungi by using polyclonal fluorescent antibodies
Kaufman, L., Standard, P. G., Jalbert, M., & Kraft, D. E. (1997) · Journal of Clinical Microbiology · doi:10.1128/jcm.35.9.2206-2209.1997 · Cited by 80 · see citing works
Polymerase Chain Reaction Detection ofAspergillusDNA in Experimental Models of Invasive Aspergillosis
Loeffler, J., Kloepfer, K., Hebart, H. F., Najvar, L. K., Graybill, J. R., Kirkpatrick, W. R., Patterson, T. F., Dietz, K., Bialek, R., & Einsele, H. (2002) · The Journal of Infectious Diseases · doi:10.1086/339824 · Cited by 79 · see citing works
Aspergillus nidulans is frequently resistant to amphotericin B
Kontoyiannis, D. P., Lewis, R. E., May, G. S., Osherov, N., & Rinaldi, M. G. (2002) · Mycoses · doi:10.1046/j.1439-0507.2002.00797.x · Cited by 75 · see citing works
Rapid Differentiation of Aspergillus Species from Other Medically Important Opportunistic Molds and Yeasts by PCR-Enzyme Immunoassay
de Aguirre, L., Hurst, S. F., Choi, J. S., Shin, J. H., Hinrikson, H. P., & Morrison, C. J. (2004) · Journal of Clinical Microbiology · doi:10.1128/jcm.42.8.3495-3504.2004 · Cited by 74 · see citing works
Development and Validation of a Quantitative Real-Time PCR Assay Using Fluorescence Resonance Energy Transfer Technology for Detection of Aspergillus fumigatus in Experimental Invasive Pulmonary Aspergillosis
O'Sullivan, C. E., Kasai, M., Francesconi, A., Petraitis, V., Petraitienė, R., Kelaher, A. M., Sarafandi, A. A., & Walsh, T. J. (2003) · Journal of Clinical Microbiology · doi:10.1128/jcm.41.12.5676-5682.2003 · Cited by 74 · see citing works
Self-citation
Evaluation of plasma (1-->3)-beta-D-glucan measurement by the kinetic turbidimetric Limulus test, for the clinical diagnosis of mycotic infections.
Mori, T., IKEMOTO, H., Matsumura, M., Yoshida, M., Inada, K., Endo, S., Ito, A., Watanabe, S., YAMAGUCHI, H., Mitsuya, M., et al. (1997) · PubMed · Cited by 73 · see citing works
Semiquantitative Detection by Real-Time PCR ofAspergillus fumigatusin Bronchoalveolar Lavage Fluids and Tissue Biopsy Specimens from Patients with Invasive Aspergillosis
Rantakokko‐Jalava, K., Laaksonen, S., Issakainen, J., Vauras, J., NIKOSKELAINEN, J., Viljanen, M. K., & Salonen, J. H. (2003) · Journal of Clinical Microbiology · doi:10.1128/jcm.41.9.4304-4311.2003 · Cited by 68 · see citing works
Pulmonary fungal infections in patients with hematological malignancies — Diagnostic approaches
von Eiff, M., Zühlsdorf, M., Roos, N., Hesse, M., Schulten, R., & van de Loo, J. (1995) · Annals of Hematology · doi:10.1007/bf01682033 · Cited by 67 · see citing works
Versatile Fluorescent Staining of Fungi in Clinical Specimens by Using the Optical Brightener Blankophor
Rüchel, R., & Schaffrinski, M. (1999) · Journal of Clinical Microbiology · doi:10.1128/jcm.37.8.2694-2696.1999 · Cited by 66 · see citing works
Production and Characterization of Recombinant Aspergillus fumigatus Cu,Zn Superoxide Dismutase and Its Recognition by Immune Human Sera
Holdom, M. D., Léchenne, B., Hay, R. J., Hamilton, A. J., & Monod, M. (2000) · Journal of Clinical Microbiology · doi:10.1128/jcm.38.2.558-562.2000 · Cited by 65 · see citing works
Characterization of AFMP1 : a Novel Target for Serodiagnosis of Aspergillosis
Yuen, K., Chan, C.-M., Chan, K.-M., Woo, P. C. Y., Che, X.-Y., Leung, A. S. P., & Cao, L. (2001) · Journal of Clinical Microbiology · doi:10.1128/jcm.39.11.3830-3837.2001 · Cited by 65 · see citing works
Evaluation of eight antibody tests and one antigen test for the diagnosis of invasive aspergillosis
Kappe, R., Schulze‐Berge, A., & Sonntag, H. (1996) · Mycoses · doi:10.1111/j.1439-0507.1996.tb00078.x · Cited by 62 · see citing works
Identification of Aspergillus fumigatus and Related Species by Nested PCR Targeting Ribosomal DNA Internal Transcribed Spacer Regions
Zhao, J., Kong, F., Li, R., Wang, X., Wan, Z., & Wang, D. (2001) · Journal of Clinical Microbiology · doi:10.1128/jcm.39.6.2261-2266.2001 · Cited by 61 · see citing works
Detection of Antibodies Specific to an Antigenic Cell Wall Galactomannoprotein for Serodiagnosis of Aspergillus fumigatus Aspergillosis
Chan, C.-M., Woo, P. C. Y., Leung, A. S. P., Lau, S. K. P., Che, X.-Y., Cao, L., & Yuen, K. (2002) · Journal of Clinical Microbiology · doi:10.1128/jcm.40.6.2041-2045.2002 · Cited by 61 · see citing works
Invasive aspergillosis in the immunocompromised host: Utiliry of computed tomography and bronchoalveolar lavage
Brown, M. J., Worthy, S. A., Flint, J. D. A., & Müller, N. L. (1998) · Clinical Radiology · doi:10.1016/s0009-9260(98)80122-0 · Cited by 59 · see citing works
Application of Nucleic Acid Sequence-Based Amplification for Diagnosis of and Monitoring the Clinical Course of Invasive Aspergillosis in Patients with Hematologic Diseases
Yoo, J., Choi, J.-H., Choi, S., Lee, D., Shin, W. S., Min, W. S., & Kim, C.-C. (2005) · Clinical Infectious Diseases · doi:10.1086/427284 · Cited by 59 · see citing works
Use of Recombinant Mitogillin for Serodiagnosis of Aspergillus fumigatus -Associated Diseases
Woo, P. C. Y., Leung, A. S. P., Lau, S. K. P., Chong, K. T. K., & Yuen, K. (2001) · Journal of Clinical Microbiology · doi:10.1128/jcm.39.12.4598-4600.2001 · Cited by 57 · see citing works
Evaluation of Calcofluor staining in the diagnosis of fungal corneal ulcer
Chander, J., Chakrabarti, A., Sharma, A., Saini, J. S., & Panigarhi, D. (1993) · Mycoses · doi:10.1111/j.1439-0507.1993.tb00758.x · Cited by 56 · see citing works
Use of Recombinant Mitogillin for Improved Serodiagnosis of Aspergillus fumigatus -Associated Diseases
Weig, M., Frosch, M., Tintelnot, K., Haas, A. V., Groß, U., Linsmeier, B., & Heesemann, J. (2001) · Journal of Clinical Microbiology · doi:10.1128/jcm.39.5.1721-1730.2001 · Cited by 56 · see citing works
Immunoperoxidase staining for identification of Aspergillus species in routinely processed tissue sections.
Verweij, P. E., Smedts, F. M. M., Poot, T., Bult, P., Hoogkamp-Korstanje, J. A. A., & Meis, J. F. G. M. (1996) · Journal of Clinical Pathology · doi:10.1136/jcp.49.10.798 · Cited by 51 · see citing works
Increased Amounts of the Aspergillus Metabolite D-Mannitol in Tissue and Serum of Rats with Experimental Aspergillosis
Wong, B., Brauer, K. L., Tsai, R. R., & Jayasimhulu, K. (1989) · The Journal of Infectious Diseases · doi:10.1093/infdis/160.1.95 · Cited by 45 · see citing works
Aspergillosis: The Most Common Community‐Acquired Pneumonia with Gram‐Negative Bacilli as Copathogens in Stem Cell Transplant Recipients with Graft‐versus‐Host Disease
Alangaden, G. J., Wahiduzzaman, M., Chandrasekar, P. H., & the Bone Marrow Transplant Group (2002) · Clinical Infectious Diseases · doi:10.1086/342061 · Cited by 45 · see citing works
Immunohistochemical Detection ofAspergillusSpecies in Pediatric Tissue Samples
Choi, J. K., Mauger, J., & McGowan, K. L. (2004) · American Journal of Clinical Pathology · doi:10.1309/dk1cg9matkyybfmq · Cited by 42 · see citing works
Cyclophosphamide Induces False-Positive Results in Detection of Aspergillus Antigen in Urine
Hashiguchi, K., Niki, Y., & Soejima, R. (1994) · CHEST Journal · doi:10.1378/chest.105.3.975b · Cited by 39 · see citing works
Impact of diagnostic markers on early antifungal therapy
Jones, B., & McLintock, L. A. (2003) · Current Opinion in Infectious Diseases · doi:10.1097/00001432-200312000-00002 · Cited by 39 · see citing works
Development of molecular methods for the identification of aspergillus and emerging moulds in paraffin wax embedded tissue sections
Paterson, P. J., Seaton, S., McLaughlin, J., & Kibbler, C. C. (2003) · Molecular Pathology · doi:10.1136/mp.56.6.368 · Cited by 37 · see citing works
Pathogenetic and Serological Aspects of Pulmonary Aspergillosis
Schønheyder, H. C. (1987) · Scandinavian Journal of Infectious Diseases · doi:10.3109/inf.1987.19.suppl-51.01 · Cited by 35 · see citing works
d -Mannitol Metabolism by Aspergillus candidus
Strandberg, G. W. (1969) · Journal of Bacteriology · doi:10.1128/jb.97.3.1305-1309.1969 · Cited by 32 · see citing works
Identification of medically important Aspergillus species by single strand conformational polymorphism (SSCP) of the PCR‐amplified intergenic spacer region Identifizierung humanmedizinisch relevanter Aspergillus‐Arten durch Analyse der Einzelstrang‐Konformations‐Polymorphismen der amplifizierten Intergenic‐Spacer‐Region
Rath, P., & Ansorg, R. (2000) · Mycoses · doi:10.1111/j.1439-0507.2000.00600.x · Cited by 27 · see citing works
Phylogenetic relationships of five species ofAspergillusand related taxa as deduced by comparison of sequences of small subunit ribosomal RNA
Verweij, P. E., Meis, J. F. G. M., van den Hurk, P., Zoll, J., Samson, R. A., & Melchers, W. J. G. (1995) · Medical Mycology · doi:10.1080/02681219580000381 · Cited by 27 · see citing works
Introducing a Molecular Test Into the Clinical Microbiology Laboratory: Development, Evaluation, and Validation
Forbes, B. A. (2003) · Archives of Pathology & Laboratory Medicine · doi:10.5858/2003-127-1106-iamtit · Cited by 26 · see citing works
Validation of assembled nucleic acid-based tests in diagnostic microbiology laboratories
Dimech, W. J., Bowden, D. S., Brestovac, B., Byron, K. A., James, G., Jardine, D. K., Sloots, T. P., & Dax, E. M. (2004) · Pathology · doi:10.1080/0031302032000174941 · Cited by 26 · see citing works
Follow‐up of anti‐Aspergillus IgG and IgA antibodies in bone marrow transplanted patients with invasive aspergillosis
Centeno-Lima, S., de Lacerda, J. M., do Carmo, J. A., Abecasis, M., Casimiro, C., & Exposto, F. (2002) · Journal of Clinical Laboratory Analysis · doi:10.1002/jcla.10035 · Cited by 24 · see citing works
False-Positive Results Caused by Cotton Swabs in Commercial Aspergillus Antigen Latex Agglutination Test
Dalle, F., López, J. B., Caillot, D., Cuisenier, B., Laubriet, A., Dumont, L., & Bonnin, A. (2002) · European Journal of Clinical Microbiology & Infectious Diseases · doi:10.1007/s10096-001-0671-3 · Cited by 22 · see citing works
Ultra fast identification of Aspergillus species in pulmonary cytology specimens by in situ hybridization.
Zimmerman, R. L., Montone, K. T., Fogt, F., & Norris, A. H. (2000) · International Journal of Molecular Medicine · doi:10.3892/ijmm.5.4.427 · Cited by 16 · see citing works
Detection of Aspergillus fumigatus hyphae by solid phase cytometry
Vos, M. M. D., & Nelis, H. J. C. F. (2003) · Journal of Microbiological Methods · doi:10.1016/s0167-7012(03)00174-x · Cited by 14 · see citing works
Forum Report: Issues in the Evaluation of Diagnostic Tests, Use of Historical Controls, and Merits of the Current Multicenter Collaborative Groups
Bennett, J. E., Kauffman, C. A., Walsh, T. J., de Pauw, B., Dismukes, W. E., Galgiani, J. N., Glauser, M. P., Herbrecht, R., Lee, J. Y., Pappas, P. G., et al. (2003) · Clinical Infectious Diseases · doi:10.1086/367840 · Cited by 14 · see citing works
Self-citation
Pulmonary Aspergillosis in a Patient with Chronic Granulomatous Disease: Confirmation by Polymerase Chain Reaction and Serological Tests, and Successful Treatment with Voriconazole
Sambatakou, H., Guiver, M., & Denning, D. W. (2003) · European Journal of Clinical Microbiology & Infectious Diseases · doi:10.1007/s10096-003-1007-2 · Cited by 13 · see citing works
Self-citation
A fatal case of disseminated aspergillosis caused by a non-sporulating strain of Aspergillus fumigatus : Figure 1
Callister, M. E. J., Griffiths, M., Nicholson, A. G., Leonard, A., Johnson, E. M., Polkey, M. I., & Kerr, J. R. (2004) · Journal of Clinical Pathology · doi:10.1136/jcp.2003.014449 · Cited by 12 · see citing works
Specimen collection, transport, and processing: mycology.
Sutton, D. A. (2006) · Cited by 8 · see citing works

Flagged first, then by citations

2 of the 137 references couldn’t be matched to a known paper.

Research works printed but not linked: 2

Review
Rath PM, Ansorg R. Identification of medically important Aspergillus species by single strand conformational polymorphism (SSCP) of the PCR-amplified intergenic spacer region. Mycoses 2000; 43: 381-86. 104

Sorted by citations

Revised Definitions of Invasive Fungal Disease from the European Organization for Research and Treatment of Cancer/Invasive Fungal Infections Cooperative Group and the National Institute of Allergy and Infectious Diseases Mycoses Study Group (EORTC/MSG) Consensus Group
De Pauw, B., Walsh, T. J., Donnelly, J. P., Stevens, D. A., Edwards, J. E., Calandra, T., Pappas, P. G., Maertens, J., Lortholary, O., Kauffman, C. A., et al. (2008) · Clinical Infectious Diseases · doi:10.1086/588660 · Cited by 4,917 · see citing works
Self-citation
Clinical practice guideline for the use of antimicrobial agents in neutropenic patients with cancer: 2010 update by the infectious diseases society of america.
Freifeld, A. G., Bow, E. J., Sepkowitz, K. A., Boeckh, M. J., Ito, J. I., Mullen, C. A., Raad, I. I., Rolston, K. V., Young, J.-A. H., & Wingard, J. R. (2011) · Clinical Infectious Diseases · doi:10.1093/cid/cir073 · Cited by 3,463 · see citing works
Practice Guidelines for the Diagnosis and Management of Aspergillosis: 2016 Update by the Infectious Diseases Society of America
Patterson, T. F., Thompson, G. R., Denning, D. W., Fishman, J. A., Hadley, S., Herbrecht, R., Kontoyiannis, D. P., Marr, K. A., Morrison, V. A., Nguyen, M. H., et al. (2016) · Clinical Infectious Diseases · doi:10.1093/cid/ciw326 · Cited by 2,926 · see citing works
Self-citation
Posaconazole vs. Fluconazole or Itraconazole Prophylaxis in Patients with Neutropenia
Cornely, O. A., Maertens, J. A., Winston, D. J., Perfect, J. R., Ullmann, A. J., Walsh, T. J., HELFGOTT, D. C., Hołowiecki, J., Stockelberg, D., Goh, Y. T., et al. (2007) · New England Journal of Medicine · doi:10.1056/nejmoa061094 · Cited by 1,802 · see citing works
Self-citation
Co-infections in people with COVID-19: a systematic review and meta-analysis.
Lansbury, L., Lim, B., Baskaran, V., & Lim, W. S. (2020) · Journal of Infection · doi:10.1016/j.jinf.2020.05.046 · Cited by 1,619 · see citing works
Nosocomial fungal infections: epidemiology, diagnosis, and treatment
Perlroth, J., Choi, B., & Spellberg, B. (2007) · Medical Mycology · doi:10.1080/13693780701218689 · Cited by 738 · see citing works
Executive Summary: Clinical Practice Guideline for the Use of Antimicrobial Agents in Neutropenic Patients with Cancer: 2010 Update by the Infectious Diseases Society of America
Freifeld, A. G., Bow, E. J., Sepkowitz, K. A., Boeckh, M. J., Ito, J. I., Mullen, C. A., RAAD, I. I., Rolston, K. V. I., Young, J. H., & Wingard, J. R. (2011) · Clinical Infectious Diseases · doi:10.1093/cid/ciq147 · Cited by 709 · see citing works
Imaging Findings in Acute Invasive Pulmonary Aspergillosis: Clinical Significance of the Halo Sign
Greene, R. E., Schlamm, H. T., Oestmann, J. W., Stark, P., Durand, C. M., Lortholary, O., Wingard, J. R., Herbrecht, R., Ribaud, P., Patterson, T. F., et al. (2007) · Clinical Infectious Diseases · doi:10.1086/509917 · Cited by 589 · see citing works
Self-citation
Long-term management of the successful adult liver transplant: 2012 practice guideline by the American Association for the Study of Liver Diseases and the American Society of Transplantation
Lucey, M. R., Terrault, N., Ojo, L., Hay, E. J., Neuberger, J., Blumberg, E., & Teperman, L. W. (2013) · Liver Transplantation · doi:10.1002/lt.23566 · Cited by 544 · see citing works
-D-Glucan Assay for the Diagnosis of Invasive Fungal Infections: A Meta-analysis
Karageorgopoulos, D. E., Vouloumanou, E. K., Ntziora, F., Michalopoulos, A., Rafailidis, P. I., & Falagas, M. E. (2011) · Clinical Infectious Diseases · doi:10.1093/cid/ciq206 · Cited by 538 · see citing works
Galactomannan in Bronchoalveolar Lavage Fluid
Meersseman, W., Lagrou, K., Maertens, J., Wilmer, A., Hermans, G., Vanderschueren, S., Spriet, I., Verbeken, E., & Van Wijngaerden, E. (2008) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200704-606oc · Cited by 496 · see citing works
Invasive pulmonary aspergillosis in patients with chronic obstructive pulmonary disease
Bulpa, P., Dive, A., & Sibille, Y. (2007) · European Respiratory Journal · doi:10.1183/09031936.00062206 · Cited by 465 · see citing works
Invasive aspergillosis in the intensive care unit
Meersseman, W., Lagrou, K., Maertens, J., & Wijngaerden, E. V. (2007) · Clinical Infectious Diseases · doi:10.1086/518852 · Cited by 366 · see citing works
Galactomannan detection for invasive aspergillosis in immunocompromized patients
Leeflang, M., Debets-Ossenkopp, Y. J., Visser, C. E., Scholten, R. J. P. M., Hooft, L., Bijlmer, H. A., Reitsma, J. B., Bossuyt, P. M., & Vandenbroucke‐Grauls, C. M. J. E. (2008) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd007394 · Cited by 362 · see citing works
Use of PCR for diagnosis of invasive aspergillosis: systematic review and meta-analysis
Mengoli, C., Cruciani, M., Barnes, R. A., Loeffler, J., & Donnelly, J. P. (2009) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(09)70019-2 · Cited by 354 · see citing works
High-frequency Triazole Resistance Found In Nonculturable Aspergillus fumigatus from Lungs of Patients with Chronic Fungal Disease
Denning, D. W., Park, S., Lass-Florl, C., Fraczek, M. G., Kirwan, M., Gore, R., Smith, J., Bueid, A., Moore, C. B., Bowyer, P., et al. (2011) · Clinical Infectious Diseases · doi:10.1093/cid/cir179 · Cited by 313 · see citing works
Self-citation
Aspergillus PCR: One Step Closer to Standardization
White, P. L., Bretagne, S., Klingspor, L., Melchers, W. J. G., McCulloch, E., Schulz, B., Finnstrom, N., Mengoli, C., Barnes, R. A., Donnelly, J. P., et al. (2010) · Journal of Clinical Microbiology · doi:10.1128/jcm.01767-09 · Cited by 296 · see citing works
Development of a simple model for studying the effects of antifungal agents on multicellular communities of Aspergillus fumigatus
Mowat, E., Butcher, J., Lang, S., Williams, C., & Ramage, G. (2007) · Journal of Medical Microbiology · doi:10.1099/jmm.0.47247-0 · Cited by 259 · see citing works
Bronchoalveolar Lavage Fluid Galactomannan for the Diagnosis of Invasive Pulmonary Aspergillosis in Patients with Hematologic Diseases
Maertens, J. A., Maertens, V., Theunissen, K., Meersseman, W., Meersseman, P., Meers, S., Verbeken, E. K., Verhoef, G. E. G., Eldere, J. V., & Lagrou, K. (2009) · Clinical Infectious Diseases · doi:10.1086/647935 · Cited by 250 · see citing works
Patients at High Risk of Invasive Fungal Infections
Rüping, M. J. G. T., Vehreschild, J. J., & Cornely, O. A. (2008) · Drugs · doi:10.2165/00003495-200868140-00002 · Cited by 248 · see citing works
Bronchoalveolar Lavage Galactomannan in Diagnosis of Invasive Pulmonary Aspergillosis among Solid-Organ Transplant Recipients
Clancy, C. J., Jaber, R. A., Leather, H. L., Wingard, J. R., Staley, B. J., Wheat, L. J., Cline, C. L., Rand, K. H., Schain, D. C., Baz, M. A., et al. (2007) · Journal of Clinical Microbiology · doi:10.1128/jcm.00077-07 · Cited by 230 · see citing works
Systematic Review and Meta-Analysis of Detecting Galactomannan in Bronchoalveolar Lavage Fluid for Diagnosing Invasive Aspergillosis
Zou, M., Tang, L., Zhao, S., Zhao, Z., Chen, L., Chen, P., Huang, Z., Li, J., Chen, L., & Fan, X. (2012) · PLoS ONE · doi:10.1371/journal.pone.0043347 · Cited by 226 · see citing works
Galactomannan detection for invasive aspergillosis in immunocompromised patients
Leeflang, M., Debets-Ossenkopp, Y. J., Wang, J., Visser, C. E., Scholten, R. J. P. M., Hooft, L., Bijlmer, H. A., Reitsma, J. B., Zhang, M., Bossuyt, P. M., et al. (2015) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd007394.pub2 · Cited by 226 · see citing works
Multiplex real-time PCR and blood culture for identification of bloodstream pathogens in patients with suspected sepsis
Westh, H., Lisby, G., Breysse, F., Böddinghaus, B., Chomarat, M., Gant, V. A., Goglio, A., Raglio, A., Schuster, H., Stüber, F., et al. (2009) · Clinical Microbiology and Infection · doi:10.1111/j.1469-0691.2009.02736.x · Cited by 224 · see citing works
Novel immunologic classification of aspergillosis in adult cystic fibrosis
Baxter, C. G., Dunn, G., Jones, A. M., Webb, A. K., Gore, R. B., Richardson, M. D., & Denning, D. W. (2013) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2013.04.007 · Cited by 213 · see citing works
Self-citation
Aspergillosis: Spectrum of Disease, Diagnosis, and Treatment
Barnes, P. D., & Marr, K. A. (2006) · Infectious Disease Clinics of North America · doi:10.1016/j.idc.2006.06.001 · Cited by 205 · see citing works
Accuracy of BAL Galactomannan in Diagnosing Invasive Aspergillosis
Guo, Y., Chen, Y., Wang, K., Qin, S., Wu, C., & Kong, J. (2010) · CHEST Journal · doi:10.1378/chest.10-0488 · Cited by 197 · see citing works
Detection of galactomannan in bronchoalveolar lavage fluid samples of patients at risk for invasive pulmonary aspergillosis: analytical and clinical validity
D'Haese, J., Theunissen, K., Vermeulen, E., Schoemans, H., De Vlieger, G., Lammertijn, L., Meersseman, P., Meersseman, W., Lagrou, K., & Maertens, J. (2012) · Journal of Clinical Microbiology · doi:10.1128/jcm.06423-11 · Cited by 186 · see citing works
Utility of Galactomannan Enzyme Immunoassay and (1,3) β- d -Glucan in Diagnosis of Invasive Fungal Infections: Low Sensitivity for Aspergillus fumigatus Infection in Hematologic Malignancy Patients
Hachem, R. Y., Kontoyiannis, D. P., Chemaly, R. F., Jiang, Y., Reitzel, R. A., & RAAD, I. I. (2008) · Journal of Clinical Microbiology · doi:10.1128/jcm.00506-08 · Cited by 184 · see citing works
Optimization of the Cutoff Value for the Aspergillus Double-Sandwich Enzyme Immunoassay
Maertens, J. A., Klont, R., Masson, C., Theunissen, K., Meersseman, W., Lagrou, K., Heinen, C., Crepin, B., Eldere, J. V., Tabouret, M., et al. (2007) · Clinical Infectious Diseases · doi:10.1086/514349 · Cited by 182 · see citing works
Review of Fungal Outbreaks and Infection Prevention in Healthcare Settings During Construction and Renovation
Kanamori, H., Rutala, W. A., Sickbert-Bennett, E. E., & Weber, D. J. (2015) · Clinical Infectious Diseases · doi:10.1093/cid/civ297 · Cited by 179 · see citing works
Invasive Mycoses: Diagnostic Challenges
Ostrosky‐Zeichner, L. (2011) · The American Journal of Medicine · doi:10.1016/j.amjmed.2011.10.008 · Cited by 178 · see citing works
Invasive Fungal Infections in Solid Organ Transplant Recipients
Shoham, S., & Marr, K. A. (2012) · Future Microbiology · doi:10.2217/fmb.12.28 · Cited by 176 · see citing works
Contribution of the (1→3)-β- d -Glucan Assay for Diagnosis of Invasive Fungal Infections
Persat, F., Ranque, S., Derouin, F., Michel-Nguyen, A., Picot, S., & Sulahian, A. (2007) · Journal of Clinical Microbiology · doi:10.1128/jcm.02091-07 · Cited by 173 · see citing works
Diagnostic contribution of positron emission tomography with [18F]fluorodeoxyglucose for invasive fungal infections
Hot, A., Maunoury, C., Poirée, S., Lanternier, F., Viard, J., Loulergue, P., Coignard-Biehler, H., Bougnoux, M., Suárez, F., Rubio, M., et al. (2010) · Clinical Microbiology and Infection · doi:10.1111/j.1469-0691.2010.03301.x · Cited by 162 · see citing works
A Breath Fungal Secondary Metabolite Signature to Diagnose Invasive Aspergillosis
Koo, S., Thomas, H. R., Daniels, S. D., Lynch, R. C., Fortier, S. M., Shea, M. M., Rearden, P., Comolli, J. C., Baden, L. R., & Marty, F. M. (2014) · Clinical Infectious Diseases · doi:10.1093/cid/ciu725 · Cited by 153 · see citing works
Risks, diagnosis and outcomes of invasive fungal infections in haematopoietic stem cell transplant recipients
Barnes, P. D., & Marr, K. A. (2007) · British Journal of Haematology · doi:10.1111/j.1365-2141.2007.06812.x · Cited by 151 · see citing works
Management of invasive pulmonary aspergillosis in non-neutropenic critically ill patients
Trof, R. J., Beishuizen, A., Debets-Ossenkopp, Y. J., Girbes, A. R. J., & Groeneveld, A. B. J. (2007) · Intensive Care Medicine · doi:10.1007/s00134-007-0791-z · Cited by 142 · see citing works
Diagnosis of invasive aspergillosis by galactomannan antigenemia detection using an enzyme immunoassay
Wheat, L. J., & Walsh, T. J. (2008) · European Journal of Clinical Microbiology & Infectious Diseases · doi:10.1007/s10096-007-0437-7 · Cited by 138 · see citing works
Self-citation
ImmunoPET/MR imaging allows specific detection of Aspergillus fumigatus lung infection in vivo
Rolle, A.-M., Hasenberg, M., Thornton, C. R., Solouk-Saran, D., Männ, L., Weski, J., Maurer, A., Fischer, E., Spycher, P. R., Schibli, R., et al. (2016) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1518836113 · Cited by 134 · see citing works
Diagnosis of Invasive Aspergillosis by a Commercial Real-Time PCR Assay for Aspergillus DNA in Bronchoalveolar Lavage Fluid Samples from High-Risk Patients Compared to a Galactomannan Enzyme Immunoassay
Torelli, R., Sanguinetti, M., Moody, A., Pagano, L., Caira, M., Carolis, E. D., Fuso, L., PASCALE, G. D., Bello, G., Antonelli, M. M., et al. (2011) · Journal of Clinical Microbiology · doi:10.1128/jcm.05026-11 · Cited by 133 · see citing works
The characteristics of Aspergillus fumigatus mycetoma development: is this a biofilm?
Mowat, E., Williams, C., Jones, B., Mcchlery, S., & Ramage, G. (2009) · Medical Mycology · doi:10.1080/13693780802238834 · Cited by 131 · see citing works
The case for antifungal stewardship
Ananda-Rajah, M. R., Slavin, M. A., & Thursky, K. (2011) · Current Opinion in Infectious Diseases · doi:10.1097/qco.0b013e32834e0680 · Cited by 128 · see citing works
Diagnosis of Histoplasmosis by Antigen Detection in BAL Fluid
Hage, C. A., Davis, T. E., Fuller, D., Egan, L., Witt, J. R., Wheat, L. J., & Knox, K. S. (2009) · CHEST Journal · doi:10.1378/chest.09-1702 · Cited by 128 · see citing works
Pathogenesis of Aspergillus fumigatus and the Kinetics of Galactomannan in an In Vitro Model of Early Invasive Pulmonary Aspergillosis: Implications for Antifungal Therapy
Hope, W. W., Kruhlak, M. J., Lyman, C. A., Petraitienė, R., Petraitis, V., Francesconi, A., Kasai, M., Mickiene, D., Sein, T., Peter, J., et al. (2007) · The Journal of Infectious Diseases · doi:10.1086/510535 · Cited by 128 · see citing works
Self-citation
68Ga-Siderophores for PET Imaging of Invasive Pulmonary Aspergillosis: Proof of Principle
Petřík, M., Haas, H., Dobrozemsky, G., Lass‐Flörl, C., Helbok, A., Blatzer, M., Dietrich, H., & Decristoforo, C. (2010) · Journal of Nuclear Medicine · doi:10.2967/jnumed.109.072462 · Cited by 128 · see citing works
Galactomannan serves as a surrogate endpoint for outcome of pulmonary invasive aspergillosis in neutropenic hematology patients
Maertens, J. A., Buvé, K., Theunissen, K., Meersseman, W., Verbeken, E. K., Verhoef, G. E. G., Eldere, J. V., & Lagrou, K. (2008) · Cancer · doi:10.1002/cncr.24022 · Cited by 127 · see citing works
Therapeutic Drug Monitoring of Voriconazole
Brüggemann, R. J. M., Donnelly, J. P., Aarnoutse, R. E., Warris, A., Blijlevens, N. M. A., Mouton, J. W., Verweij, P. E., & Burger, D. M. (2008) · Therapeutic Drug Monitoring · doi:10.1097/ftd.0b013e31817b1a95 · Cited by 125 · see citing works
Use and Limits of (1-3)-β- d -Glucan Assay (Fungitell), Compared to Galactomannan Determination (Platelia Aspergillus), for Diagnosis of Invasive Aspergillosis
Sulahian, A., Porcher, R., Bergeron, A., Touratier, S., Raffoux, E., Ménotti, J., Derouin, F., & Ribaud, P. (2014) · Journal of Clinical Microbiology · doi:10.1128/jcm.03567-13 · Cited by 124 · see citing works
Preclinical evaluation of two 68Ga-siderophores as potential radiopharmaceuticals for Aspergillus fumigatus infection imaging
Petřík, M., Franssen, G. M., Haas, H., Laverman, P., Hörtnagl, C., Schrettl, M., Helbok, A., Lass‐Flörl, C., & Decristoforo, C. (2012) · European Journal of Nuclear Medicine and Molecular Imaging · doi:10.1007/s00259-012-2110-3 · Cited by 123 · see citing works
Overcoming antifungal resistance
Srinivasan, A., Lopez-Ribot, J. L., & Ramasubramanian, A. K. (2014) · Drug Discovery Today Technologies · doi:10.1016/j.ddtec.2014.02.005 · Cited by 121 · see citing works
Cross-reactivity of non-Aspergillus fungal species in the Aspergillus galactomannan enzyme immunoassay
Cummings, J. R., Jamison, G. R., Boudreaux, J. W., Howles, M. J., Walsh, T. J., & Hayden, R. T. (2007) · Diagnostic Microbiology and Infectious Disease · doi:10.1016/j.diagmicrobio.2007.04.022 · Cited by 116 · see citing works
Self-citation
Revisión sistemática de las publicaciones sobre diagnóstico de la aspergilosis invasora mediante reacción en cadena de la polimerasa (PCR) de lavados bronco-alveolares
Tuon, F. F. (2007) · Revista Iberoamericana de Micología · doi:10.1016/s1130-1406(07)70020-7 · Cited by 116 · see citing works
Antibody testing in aspergillosis—quo vadis?
Page, I. D., Richardson, M. D., & Denning, D. W. (2015) · Medical Mycology · doi:10.1093/mmy/myv020 · Cited by 108 · see citing works
Self-citation
Prognostic Features of Galactomannan Antigenemia in Galactomannan-Positive Invasive Aspergillosis
Koo, S., Porter, J., Baden, L. R., & Marty, F. M. (2010) · Journal of Clinical Microbiology · doi:10.1128/jcm.02281-09 · Cited by 103 · see citing works
Fungal Infections of the CNS
Black, K. E., & Baden, L. R. (2007) · CNS Drugs · doi:10.2165/00023210-200721040-00004 · Cited by 101 · see citing works
Earlier Diagnosis of Invasive Fusariosis with Aspergillus Serum Galactomannan Testing
Nucci, M., Carlesse, F. A. D. M. C., Cappellano, P., Varon, A. G., Seber, A., Garnica, M. M., Nouér, S. A., & Colombo, A. L. (2014) · PLoS ONE · doi:10.1371/journal.pone.0087784 · Cited by 99 · see citing works
Trends in hospitalizations related to invasive aspergillosis and mucormycosis in the United States, 2000–2013
Vallabhaneni, S., Benedict, K., Derado, G., & Mody, R. K. (2017) · Open Forum Infectious Diseases · doi:10.1093/ofid/ofw268 · Cited by 98 · see citing works
Aspergillus to Zygomycetes: Causes, Risk Factors, Prevention, and Treatment of Invasive Fungal Infections
Cornely, O. A. (2008) · Infection · doi:10.1007/s15010-008-7357-z · Cited by 97 · see citing works
Use of Bronchoalveolar Lavage To Detect Galactomannan for Diagnosis of Pulmonary Aspergillosis among Nonimmunocompromised Hosts
Nguyen, M. H., Jaber, R. A., Leather, H. L., Wingard, J. R., Staley, B. J., Wheat, L. J., Cline, C. L., Baz, M. A., Rand, K. H., & Clancy, C. J. (2007) · Journal of Clinical Microbiology · doi:10.1128/jcm.00716-07 · Cited by 97 · see citing works
Epidemiology, diagnosis and treatment of fungal respiratory infections in the critically ill patient.
Garnacho‐Montero, J., Olaechea, P., Álvarez-Lerma, F., Álvarez-Rocha, L., Blanquer, J., Galván, B., Rodríguez, A. H., Zaragoza, R., Aguado, J. M., Mensa, J., et al. (2013) · PubMed · Cited by 97 · see citing works
Insights into fungal communities in composts revealed by 454-pyrosequencing: implications for human health and safety
de Gannes, V., Eudoxie, G. D., & Hickey, W. J. (2013) · Frontiers in Microbiology · doi:10.3389/fmicb.2013.00164 · Cited by 96 · see citing works
A prospective survey of Aspergillus spp. in respiratory tract samples: prevalence, clinical impact and antifungal susceptibility
Mortensen, K. L., Johansen, H. K., Fuursted, K., Knudsen, J. D., Gahrn-Hansen, B., Jensen, R. H., Howard, S. J., & Arendrup, M. C. (2011) · European Journal of Clinical Microbiology & Infectious Diseases · doi:10.1007/s10096-011-1229-7 · Cited by 92 · see citing works
Polymerase chain reaction blood tests for the diagnosis of invasive aspergillosis in immunocompromised people
Cruciani, M., Mengoli, C., Loeffler, J., Donnelly, P., Barnes, R. A., Jones, B. L., Klingspor, L., Morton, C. O., & Maertens, J. A. (2015) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd009551.pub3 · Cited by 90 · see citing works
High-volume culture and quantitative real-time PCR for the detection of Aspergillus in sputum
Vergidis, P., Moore, C. B., Frazer, L. N., Rautemaa‐Richardson, R., Walker, A., Denning, D. W., & Richardson, M. D. (2019) · Clinical Microbiology and Infection · doi:10.1016/j.cmi.2019.11.019 · Cited by 90 · see citing works
Self-citation
Aspergillus Galactomannan Enzyme-Linked Immunosorbent Assay Cross-Reactivity Caused by Invasive Geotrichum capitatum
Giacchino, M., Chiapello, N., Bezzio, S., Fagioli, F., Saracco, P., Alfarano, A., Martini, V., Cimino, G. G., Martino, P., & Girmenia, C. (2006) · Journal of Clinical Microbiology · doi:10.1128/jcm.00856-06 · Cited by 90 · see citing works
Proteome Profiling and Functional Classification of Intracellular Proteins from Conidia of the Human-Pathogenic Mold Aspergillus fumigatus
Teutschbein, J., Albrecht, D., Pötsch, M., Guthke, R., Aimanianda, V., Clavaud, C., Latgé, J., Brakhage, A. A., & Kniemeyer, O. (2010) · Journal of Proteome Research · doi:10.1021/pr9010684 · Cited by 89 · see citing works
Galactomannan detection in broncho-alveolar lavage fluid for invasive aspergillosis in immunocompromised patients
de Heer, K., Gerritsen, M. G., Visser, C. E., & Leeflang, M. (2019) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd012399.pub2 · Cited by 88 · see citing works
Distinct Innate Immune Phagocyte Responses to Aspergillus fumigatus Conidia and Hyphae in Zebrafish Larvae
Knox, B. P., Deng, Q., Rood, M., Eickhoff, J. C., Keller, N. P., & Anna Huttenlocher, A. (2014) · Eukaryotic Cell · doi:10.1128/ec.00080-14 · Cited by 88 · see citing works
Evaluation of PCR on Bronchoalveolar Lavage Fluid for Diagnosis of Invasive Aspergillosis: A Bivariate Metaanalysis and Systematic Review
Sun, W., Wang, K., Gao, W., Su, X., Qian, Q., Lu, X., Song, Y., Guo, Y., & Shi, Y. P. (2011) · PLoS ONE · doi:10.1371/journal.pone.0028467 · Cited by 86 · see citing works
Pneumonia in the neutropenic cancer patient
Evans, S. E., & Ost, D. E. (2015) · Current Opinion in Pulmonary Medicine · doi:10.1097/mcp.0000000000000156 · Cited by 84 · see citing works
Molecular Detection and Species-Specific Identification of Medically Important Aspergillus Species by Real-Time PCR in Experimental Invasive Pulmonary Aspergillosis
Walsh, T. J., Wissel, M., Grantham, K. J., Petraitienė, R., Petraitis, V., Kasai, M., Francesconi, A., Cotton, M. P., Hughes, J. E., Greene, L., et al. (2011) · Journal of Clinical Microbiology · doi:10.1128/jcm.00570-11 · Cited by 84 · see citing works
Self-citation
Volume dependency for culture of fungi from respiratory secretions and increased sensitivity of A spergillus quantitative PCR
Fraczek, M. G., Kirwan, M., Moore, C. B., Morris, J., Denning, D. W., & Richardson, M. D. (2013) · Mycoses · doi:10.1111/myc.12103 · Cited by 83 · see citing works
Self-citation
Combined real‐time PCR and galactomannan surveillance improves diagnosis of invasive aspergillosis in high risk patients with haematological malignancies
Rogers, T. R., Morton, C. O., Springer, J., Conneally, E., Heinz, W., Kenny, C. C., Frost, S., Einsele, H., & Loeffler, J. (2013) · British Journal of Haematology · doi:10.1111/bjh.12285 · Cited by 79 · see citing works
Polymerase chain reaction blood tests for the diagnosis of invasive aspergillosis in immunocompromised people
Cruciani, M., Mengoli, C., Barnes, R. A., Donnelly, J. P., Loeffler, J., Jones, B. L., Klingspor, L., Maertens, J. A., Morton, C. O., & White, L. P. (2019) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd009551.pub4 · Cited by 79 · see citing works
Advances in the serological diagnosis of invasive Aspergillus infections in patients with haematological disorders
Maertens, J. A., Theunissen, K., Lodewyck, T., Lagrou, K., & Eldere, J. V. (2007) · Mycoses · doi:10.1111/j.1439-0507.2007.01375.x · Cited by 78 · see citing works
Fungal infections in adult patients on extracorporeal life support
Cavayas, Y. A., Yusuff, H. O., & Porter, R. (2018) · Critical Care · doi:10.1186/s13054-018-2023-z · Cited by 78 · see citing works
A prospective comparison of galactomannan in bronchoalveolar lavage fluid for the diagnosis of pulmonary invasive aspergillosis in medical patients under intensive care: comparison with the diagnostic performance of galactomannan and of (1→ 3) – β – d-glucan chromogenic assay in serum samples
Acosta, J., Catalán, M., del Palacio‐Pérez‐Medel, Á., Lora, D., Montejo, J. C., Cuétara, M. S., Moragues, M. D., Pontón, J., & del Palacio, A. (2010) · Clinical Microbiology and Infection · doi:10.1111/j.1469-0691.2010.03357.x · Cited by 77 · see citing works
Characterization and Comparison of Galactomannan Enzyme Immunoassay and Quantitative Real-Time PCR Assay for Detection of Aspergillus fumigatus in Bronchoalveolar Lavage Fluid from Experimental Invasive Pulmonary Aspergillosis
Francesconi, A., Kasai, M., Petraitienė, R., Petraitis, V., Kelaher, A. M., Schaufele, R. L., Hope, W. W., M.S., Y. R. S., Bacher, J. D., & Walsh, T. J. (2006) · Journal of Clinical Microbiology · doi:10.1128/jcm.02693-05 · Cited by 76 · see citing works
Self-citation
Aspergillosis in Chronic Granulomatous Disease
King, J., Henriet, S., & Warris, A. (2016) · Journal of Fungi · doi:10.3390/jof2020015 · Cited by 76 · see citing works
Prospective Evaluation of Clinical and Biological Markers To Predict the Outcome of Invasive Pulmonary Aspergillosis in Hematological Patients
Bergeron, A., Porcher, R., Ménotti, J., POIROT, J. L., Chagnon, K., Vekhoff, A., Cornet, M., Isnard, F., Raffoux, E., Brethon, B., et al. (2011) · Journal of Clinical Microbiology · doi:10.1128/jcm.00750-11 · Cited by 75 · see citing works
In Vitro Release by Aspergillus fumigatus of Galactofuranose Antigens, 1,3-β- d -Glucan, and DNA, Surrogate Markers Used for Diagnosis of Invasive Aspergillosis
Mennink‐Kersten, M. A. S. H., Ruegebrink, D., Wasei, N., Melchers, W. J. G., & Verweij, P. E. (2006) · Journal of Clinical Microbiology · doi:10.1128/jcm.44.5.1711-1718.2006 · Cited by 75 · see citing works
Galactomannan Antigenemia in Pediatric Oncology Patients With Invasive Aspergillosis
Hayden, R. T., Pounds, S. B., Knapp, K. M., Petraitienė, R., Schaufele, R. L., Sein, T., & Walsh, T. J. (2008) · The Pediatric Infectious Disease Journal · doi:10.1097/inf.0b013e31817197ab · Cited by 74 · see citing works
Self-citation
Role of Non-Culture-Based Tests, with an Emphasis on Galactomannan Testing for the Diagnosis of Invasive Aspergillosis
Maertens, J. A., & Miceli, M. H. (2015) · Seminars in Respiratory and Critical Care Medicine · doi:10.1055/s-0035-1562892 · Cited by 74 · see citing works
Update on the contribution of galactomannan for the diagnosis of invasive aspergillosis
Aquino, V. R., Goldani, L. Z., & Pasqualotto, A. C. (2007) · Mycopathologia · doi:10.1007/s11046-007-9010-2 · Cited by 73 · see citing works
Current Status and Future Perspectives on Molecular and Serological Methods in Diagnostic Mycology
Lau, A. F., Chen, W., Sleiman, S., & Sorrell, T. C. (2009) · Future Microbiology · doi:10.2217/fmb.09.70 · Cited by 73 · see citing works
Molecular Diagnosis of Invasive Aspergillosis and Detection of Azole Resistance by a Newly Commercialized PCR Kit
Dannaoui, É., Gabriel, F., Gaboyard, M., Lagardere, G., Audebert, L., Quesne, G., Godichaud, S., Verweij, P. E., Accoceberry, I., & Bougnoux, M. (2017) · Journal of Clinical Microbiology · doi:10.1128/jcm.01032-17 · Cited by 72 · see citing works
New Concepts in Diagnostics for Invasive Mycoses: Non-Culture-Based Methodologies
Patterson, T. F., & Donnelly, J. P. (2019) · Journal of Fungi · doi:10.3390/jof5010009 · Cited by 72 · see citing works
Two‐dimensional proteome reference maps for the human pathogenic filamentous fungus Aspergillus fumigatus
Vödisch, M., Albrecht, D., Leßing, F., Schmidt, A. D., Winkler, R., Guthke, R., Brakhage, A. A., & Kniemeyer, O. (2009) · PROTEOMICS · doi:10.1002/pmic.200800394 · Cited by 71 · see citing works
Identification of a Putative Crf Splice Variant and Generation of Recombinant Antibodies for the Specific Detection of Aspergillus fumigatus
Schütte, M., Thullier, P., Pelat, T., Wezler, X., Rosenstock, P., Hinz, D., Kirsch, M. I., Hasenberg, M., Frank, R., Schirrmann, T., et al. (2009) · PLoS ONE · doi:10.1371/journal.pone.0006625 · Cited by 70 · see citing works
MALDI-TOF MS proteomic phenotyping of filamentous and other fungi from clinical origin
CHIERICO, F. D., Masotti, A., Onori, M., Fiscarelli, E. V., Mancinelli, L., Ricciotti, G., Alghisi, F., Dimiziani, L., Manetti, C., Urbani, A., et al. (2012) · Journal of Proteomics · doi:10.1016/j.jprot.2012.03.048 · Cited by 69 · see citing works
Primary antifungal prophylaxis in leukaemia patients
Maertens, J. A., Frère, P., Lass‐Flörl, C., Heinz, W., & Cornely, O. A. (2007) · European Journal of Cancer Supplements · doi:10.1016/j.ejcsup.2007.06.006 · Cited by 68 · see citing works
Evaluation of MycAssay™ Aspergillus for Diagnosis of Invasive Pulmonary Aspergillosis in Patients without Hematological Cancer
Guinea, J., Padilla, C., Escribano, P., Muñóz, P., Padilla, B., Gijón, P., & Bouza, E. (2013) · PLoS ONE · doi:10.1371/journal.pone.0061545 · Cited by 65 · see citing works
Approaches to the Management of Invasive Fungal Infections in Hematologic Malignancy and Hematopoietic Cell Transplantation
Michallet, M., & Ito, J. I. (2009) · Journal of Clinical Oncology · doi:10.1200/jco.2008.20.1178 · Cited by 64 · see citing works
Diagnosis of invasive pulmonary aspergillosis: Updates and recommendations
Désoubeaux, G., Bailly, É., & Chandenier, J. (2014) · Médecine et Maladies Infectieuses · doi:10.1016/j.medmal.2013.11.006 · Cited by 64 · see citing works
Guidelines for the prevention of invasive mould diseases caused by filamentous fungi by the Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC)
Ruíz-Camps, I., Aguado, J. M., Almirante, B., Bouza, E., Ferrer, C., Len, Ó., López‐Cerero, L., Rodríguez-Tudela, J. L., Ruiz, M. S., Solé, A., et al. (2011) · Clinical Microbiology and Infection · doi:10.1111/j.1469-0691.2011.03477.x · Cited by 64 · see citing works
Neutrophil Interactions Stimulate Evasive Hyphal Branching by Aspergillus fumigatus
Ellett, F. E., Jorgensen, J. A., Frydman, G. H., Jones, C. N., & Irimia, D. (2017) · PLoS Pathogens · doi:10.1371/journal.ppat.1006154 · Cited by 62 · see citing works
Galactomannan in bronchoalveolar lavage fluid for diagnosis of invasive aspergillosis in non-hematological patients
Fortün, J., Martín‐Dávila, P., de la Pedrosa, E. G. G., Silva, J. T., García‐Rodríguez, J., Benito, D., Rullo, E. V., Castaño, F., Fernández‐Ruiz, M., Lázaro, F., et al. (2016) · Journal of Infection · doi:10.1016/j.jinf.2016.02.019 · Cited by 61 · see citing works
Epidemiology and Outcomes of Hospitalizations With Invasive Aspergillosis in the United States, 2009–2013
Zilberberg, M. D., Nathanson, B. H., Harrington, R. L., Spalding, J. R., & Shorr, A. F. (2018) · Clinical Infectious Diseases · doi:10.1093/cid/ciy181 · Cited by 60 · see citing works
Risk Factors Associated With Invasive Fungal Disease in Children With Cancer and Febrile Neutropenia
Milena Villarroel, C., Avilés, C. L., Silva, P., Guzmán, A. M., Helena Poggi, M., Alvarez, A., Becker, A., O’Ryan, M., Salgado, C., Topelberg, S., V, et al. (2010) · The Pediatric Infectious Disease Journal · doi:10.1097/inf.0b013e3181e7db7f · Cited by 58 · see citing works

Authors: Hope, W., Walsh, T., & Denning, D.
Affiliations: National Institutes of Health (US)
Venue: The Lancet Infectious Diseases
Publisher: Elsevier BV
Published: 2005-10
Volume: 5
Issue: 10
Pages: 609-622
ISSN: 1473-3099 (ISSN-L)
DOI: 10.1016/s1473-3099(05)70238-3
OpenAlex: W2066421491
Cited by: 495
References: 137
Citations by year: 2026: 9 · 2025: 10 · 2024: 12 · 2023: 12 · 2022: 15 · 2021: 13 · 2020: 9 · 2019: 21 · 2018: 15 · 2017: 23 · 2016: 30 · 2015: 36 · 2014: 23 · 2013: 30 · 2012: 33
FWCI: 4.42
Type: journal article
Language: en
Open access: green
research.manchester.ac.uk
Licence: other-oa
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/legal/tdmrep-license (tdm)
Locations: The Lancet Infectious Diseases (publishedVersion)
PubMed (publishedVersion)
Research Explorer (The University of Manchester) (publishedVersion, other-oa)
Topics: Health Sciences › Medicine › Infectious Diseases › Antifungal resistance and susceptibility
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Fungal and yeast genetics research
Health Sciences › Medicine › Epidemiology › Fungal Infections and Studies
Keywords: invasive aspergillosis, Aspergillus, laboratory diagnosis, galactomannan, β-1,3-glucan, molecular diagnosis, serological diagnosis, fungal DNA detection, critically ill patients
MeSH terms: Antibodies, Fungal, Aspergillosis, Aspergillus, DNA, Fungal, Galactose, Humans, Mannans, Clinical Laboratory Techniques

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Laboratory diagnosis of invasive aspergillosis

Abstract

Integrity signals

Claims the paper makes

Claims other papers make about this one

Self-check

Cites

Cited by

Related

Record

About these checks