Cited by 330Antifungal resistance and susceptibilityFungal and yeast genetics researchFungal Infections and Studies

A new sensitive sandwich enzyme-linked immunosorbent assay to detect galactofuran in patients with invasive aspergillosis

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Stynen, D, Goris, A, Sarfati, J, Latgé, J P·1995·Journal of Clinical Microbiology

Abstract

A double-direct sandwich enzyme-linked immunosorbent assay that uses a rat anti-galactomannan monoclonal antibody as the acceptor and detector antibody was designed. This immunoassay, which detects less than 1 ng of galactomannan per ml, was assessed in a retrospective study with samples from patients with invasive aspergillosis. Serum is more appropriate than urine for use in the search for circulating galactomannan. Antigenemia does not have a transient character. Galactomannan can be detected at least 39 days before the death of the patients.

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Crossref · 10.1128/jcm.33.2.497-500.1995

Cites

20 of 20 references verified0 citation errors · 0 not checkable

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Research works printed but not linked: 1

  1. Bodey G. P., Vartivarian S. Aspergillosis. Eur J Clin Microbiol Infect Dis. 1989 May;8(5):413–437. doi: 10.1007/BF01964057. [DOI] [PubMed] [Google Scholar] · DOI

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Authors
Stynen, D., Goris, A., Sarfati, J., & Latgé, J. P.
Affiliations
Sanofi (Belgium) (BE)
Venue
Journal of Clinical Microbiology
Published
1995-02
Volume
33
Issue
2
Pages
497-500
ISSN
  • 0095-1137 (ISSN-L)
  • 1098-660X
OpenAlex
W2123332089
Cited by
330
References
20
Citations by year
2026: 4 · 2025: 5 · 2024: 4 · 2023: 2 · 2022: 5 · 2021: 7 · 2020: 5 · 2019: 13 · 2018: 9 · 2017: 6 · 2016: 6 · 2015: 6 · 2014: 9 · 2013: 8 · 2012: 14
FWCI
7.46
Type
journal article
Language
en
Open access
Locations
  • Journal of Clinical Microbiology (publishedVersion)
  • Europe PMC (PubMed Central) (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Infectious Diseases › Antifungal resistance and susceptibility
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Fungal and yeast genetics research
  • Health Sciences › Medicine › Epidemiology › Fungal Infections and Studies
Keywords
galactomannan, invasive aspergillosis, sandwich ELISA, serum biomarkers, antigenemia, Aspergillus, fungal infection diagnosis
MeSH terms
Adolescent, Adult, Antigens, Fungal, Aspergillosis, Aspergillus, Child, Preschool, Enzyme-Linked Immunosorbent Assay, Evaluation Studies as Topic, False Positive Reactions, Female, Galactose, Humans, Male, Mannans, Middle Aged, Opportunistic Infections, Sensitivity and Specificity

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