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Recurrent MLK4 Loss-of-Function Mutations Suppress JNK Signaling to Promote Colon Tumorigenesis

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Regulated Expression of a Tumor-Associated Antigen Reveals Multiple Levels of T-Cell Tolerance in a Mouse Model of Lung Cancer

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The road to integrative cancer therapies: emergence of a tumor-associated fibroblast protease as a potential therapeutic target in cancer

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Cholecystokinin Receptor Antagonist Halts Progression of Pancreatic Cancer Precursor Lesions and Fibrosis in Mice

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Ras Dimer Formation as a New Signaling Mechanism and Potential Cancer Therapeutic Target

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miR-802 Suppresses Acinar-to-Ductal Reprogramming During Early Pancreatitis and Pancreatic Carcinogenesis

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Genetic disruption of oncogenic Kras sensitizes lung cancer cells to Fas receptor-mediated apoptosis

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A guide to ERK dynamics, part 2: downstream decoding

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TSH Signaling Overcomes B-RafV600E–Induced Senescence in Papillary Thyroid Carcinogenesis through Regulation of DUSP6

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Proteasome-dependent degradation of Smad7 is critical for lung cancer metastasis

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Oncogene-induced senescence: An essential role for Runx

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Targeting oncogenic Ras: Figure 1.Preprint

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KRAS gene mutations in lung cancer: Particulars established and issues unresolved

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A requirement for wild-type Ras isoforms in mutant KRas-driven signalling and transformation

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Genetic epistasis between heparan sulfate and FGF–Ras signaling controls lens development

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The Ability of E1A to Rescue ras-Induced Premature Senescence and Confer Transformation Relies on Inactivation of Both p300/CBP and Rb Family Proteins

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Diverging gain-of-function mechanisms of two novel KRAS mutations associated with Noonan and cardio-facio-cutaneous syndromes

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Phosphatome profiling reveals PTPN2, PTPRJ and PTEN as potent negative regulators of PKB/Akt activation in Ras-mutated cancer cells

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Retinal Proteoglycans Act as Cellular Receptors for Basement Membrane Assembly to Control Astrocyte Migration and Angiogenesis

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Mosaicism in Cutaneous Disorders

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Acidic fibroblast growth factor underlies microenvironmental regulation of MYC in pancreatic cancer

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Activated Wnt Signaling in Stroma Contributes to Development of Pancreatic Mucinous Cystic Neoplasms

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p204, a p200 family protein, as a multifunctional regulator of cell proliferation and differentiation

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Gene expression deregulation by KRAS G12D and G12V in a BRAF V600E context

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Sleeping beauty: a novel cancer gene discovery tool

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Challenges and advances in mouse modeling for human pancreatic tumorigenesis and metastasis

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Novel findings and expansion of phenotype in a mosaic RASopathy caused by somatic KRAS variants

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The K-Ras 4A isoform promotes apoptosis but does not affect either lifespan or spontaneous tumor incidence in aging mice

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KDM6A regulates cell plasticity and pancreatic cancer progression by noncanonical activin pathway

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Frs2α and Shp2 signal independently of Gab to mediate FGF signaling in lens development

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Genomic characterization of patient-derived xenograft models established from fine needle aspirate biopsies of a primary pancreatic ductal adenocarcinoma and from patient-matched metastatic sites

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Loss of TET reprograms Wnt signaling through impaired demethylation to promote lung cancer development

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Differential Oncogenic Ras Signaling and Senescence in Tumor Cells

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Modulation of Bax and mTOR for Cancer Therapeutics

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Drug library screen reveals benzimidazole derivatives as selective cytotoxic agents for KRAS-mutant lung cancer

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