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Evidence of Cooperation between Hippo Pathway and RAS Mutation in Thyroid Carcinomas

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Target-Specific Nanoparticle Polyplex Down-Regulates Mutant Kras to Prevent Pancreatic Carcinogenesis and Halt Tumor Progression

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KRAS K104 modification affects the KRASG12D-GEF interaction and mediates cell growth and motility

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Considerations for skin carcinogenesis experiments using inducible transgenic mouse models

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Deficient FGF signaling in the developing peripheral retina disrupts ciliary margin development and causes aniridiaPreprint

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The CLCF1-CNTFR axis drives an immunosuppressive tumor microenvironment and blockade enhances the effects of established cancer therapiesPreprint

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Differential Activity of the KRAS Oncogene by Method of Activation: Implications for Signaling and Therapeutic Intervention

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Spliceosome induction is a druggable dependency of RAS-driven senescence and cancer

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Inhibition of the minor spliceosome restricts the growth of a broad spectrum of cancers

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Probe-free allele-specific copy number detection and analysis of tumors

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The cis‐regulatory switchboard of pancreatic ductal cancer

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KRAS/NRAS Gene Mutations and the Efficacy of Bortezomib-Based Triplet Induction Therapy in Patients with Newly Diagnosed Multiple Myeloma

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The Positive Feedback Loop Between Inflammation and Mutant KRAS Genes Promotes Malignant Transformation in Chronic Pancreatitis

Yang, F., Li, L., & Kong, X. (2022) · Cancer Screening and Prevention · doi:10.14218/csp.2022.00012 · Cited by 2

CRISPR/Cas9 engineering offers new opportunities to model pancreatic ductal adenocarcinoma development

Jørgensen, C., & Hogg, E. K. J. (2016) · Translational Cancer Research · doi:10.21037/tcr.2016.08.01 · Cited by 2

Molecular Genetic Markers in Female Reproductive Cancers

Wang, T., Davidson, B., Buckhaults, P., Huang, C., & Pohl, G. (2010) · Journal of Oncology · doi:10.1155/2010/307460 · Cited by 2

The cooperation between p53 and Ras in tumori-genesis

Yong-Yong, W. E. I., Hou, J. Y., Tang, W., & Luo, Y. (2012) · Hereditas (Beijing) · doi:10.3724/sp.j.1005.2012.01513 · Cited by 2

Endogenous locus-driven H-Ras G12V expression induces senescence-like phenotype in primary fibroblasts of the Costello syndrome mouse model

Chennappan, S., Schulze, T., & Cirstea, I. C. (2017) · Molecular Life · doi:10.26600/mollife.1.1.1.2017 · Cited by 2

Intestinal homeostasis and neoplasia studied using conditional transgenesis

Marsh, V. L., & Clarke, A. R. (2007) · Expert Review of Anticancer Therapy · doi:10.1586/14737140.7.4.519 · Cited by 2

Constitutively active RAS in S. pombe causes persistent Cdc42 signalling but only transient MAPK activationPreprint

Kelsall, E. J., Vértesy, Á., Straatman, K. R., Tariq, M., Gadea, R., Parmar, C., Schreiber, G., Randhawa, S., Dominguez, C., Klipp, E., et al. (2018) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/380220 · Cited by 2

Shc1 cooperates with Frs2 and Shp2 to recruit Grb2 in FGF-induced lens developmentPreprint

Wang, Q., Li, H., Mao, Y., Garg, A., Park, E. S., Wu, Y., Chow, A., Peregrin, J., & Zhang, X. (2025) · eLife · doi:10.7554/elife.103615.2 · Cited by 2

Baseline expression of c-Myc defines the tissue specificity of oncogenic K-RasPreprint

Popow, O., Yu, Q., Yapp, C., Hull, S., Paulo, J. A., Hanna, B., Xu, S., Kuang, Y., Sigel, C., Paweletz, C. P., et al. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.07.21.665965 · Cited by 2

The rise of RAS: how gradual oncogene activation shapes the OIS spectrumPreprint

Zhu, H., Chan, A. S. L., & Narita, M. (2025) · Genes & Development · doi:10.1101/gad.352761.125 · Cited by 2

Endogenous insulin contributes to pancreatic cancer developmentPreprint

Zhang, A. M. Y., Magrill, J., de Winter, T. J. J., Hu, X., Skovsø, S., Schaeffer, D. F., Kopp, J. L., & Johnson, J. D. (2019) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/530097 · Cited by 2

Monoallelic KRAS (G13C) mutation triggers dysregulated expansion in induced pluripotent stem cell-derived hematopoietic progenitor cells

Lin, H.-T., Takagi, M., Kubara, K., Yamazaki, K., Michikawa, F., Okumura, T., Naruto, T., Morio, T., Miyazaki, K., Taniguchi, H., et al. (2024) · Stem Cell Research & Therapy · doi:10.1186/s13287-024-03723-2 · Cited by 1

Differential effects of KRAS G-domain and hypervariable region mutants on cancer phenotypes

de Borja, J. A. D., Lin, K. D. J. H., Mirador, D. A. R., Ang, A. I. D., Chua, S. A. A., Sytangco, J. M. D., Sacdalan, D. L., & Garcia, R. L. (2025) · Scientific Reports · doi:10.1038/s41598-025-22168-y · Cited by 1

KRAS Mutations Reprogram RNA m6A Modifications to Drive CD73-Dependent Immune Evasion in Colorectal Cancer

Shin, S., Hong, S.-P., Lee, S., Jang, Y., Yang, J., Oh, J., Jang, D., Lee, S.-J., Kim, J., Lee, S. E., et al. (2026) · Cancer Research · doi:10.1158/0008-5472.can-26-0403 · Cited by 1

Development of a new flippase-dependent mouse model for red fluorescence-based isolation of KRASG12D oncogene-expressing tumor cells

Hrčkulák, D., Onhajzer, J., Krausová, M., Šťastná, M., Křı́ž, V., Janečková, L., & Kořínek, V. (2025) · Transgenic Research · doi:10.1007/s11248-024-00429-2 · Cited by 1

Leukemogenic Kras mutation reprograms multipotent progenitors to facilitate its spread through the hematopoietic system

Jang, G., Park, R., Esteva, E., Hsu, P.-F., Feng, J., Upadhaya, S., Sawai, C. M., Aifantis, I., Fooksman, D., & Reizis, B. (2025) · The Journal of Experimental Medicine · doi:10.1084/jem.20240587 · Cited by 2

Senescence-directed nanotherapy ameliorates fibrosis and overcomes immune exclusion in cancer

Hinterleitner, C., Barthet, V. J. A., Goldberg, H. V., Vogt, K. C., Perea, A. M., Hillger, L. R., Ruiz, S. B., McHugh, D., Ho, Y.-J., Perez, A. C., et al. (2026) · Science · doi:10.1126/science.aeg4791 · Cited by 1

Myeloid-derived TGFβ1 and oncostatin M establish two distinct stromal niches controlling late and hybrid EMT states

Dong, A., Vanuytven, S., González, A. P., Bévant, K., de Putte, L. V., Zahedi, Z., Allard, J., Dubois, C., Salmon, I. J., Rorive, S., et al. (2026) · Nature Cancer · doi:10.1038/s43018-026-01259-3 · Cited by 1

Robert J Gorlin, DDS, MS (1923–2006): a geneticist for all seasons

Eng, C. (2007) · PubMed Central · Cited by 1

Genetic Susceptibility and High Risk Groups for Pancreatic Cancer

Greenhalf, W., & Neoptolemos, J. P. (2009) · Springer eBooks · doi:10.1007/978-0-387-77498-5_24 · Cited by 1

Tumor induction by an endogenous K-ras oncogene is highly dependent on cellular context

Guerra, C. E., Mijimolle, N., Dhawahir, A., Dubus, P. R., Barradas, M., Serrano, M., Campuzano, V., & Barbacid, M. (2003) · Cancer Cell · doi:10.1016/s1535-6108(03)00191-0 · Cited by 577

Mouse Tissues that Undergo Neoplastic Progression after K-Ras Activation Are Distinguished by Nuclear Translocation of phospho-Erk1/2 and Robust Tumor Suppressor Responses

Parikh, N., Shuck, R. L., Nguyen, T., Herron, A. J., & Donehower, L. A. (2012) · Molecular Cancer Research · doi:10.1158/1541-7786.mcr-12-0089 · Cited by 21

Conditional Expression of K- ras in an Epithelial Compartment that Includes the Stem Cells Is Sufficient to Promote Squamous Cell Carcinogenesis

Vitale-Cross, L. A., Amornphimoltham, P., Fisher, G. H., Molinolo, A., & Gutkind, J. S. (2004) · Cancer Research · doi:10.1158/0008-5472.can-04-2623 · Cited by 133

Somatic activation of oncogenic Kras in hematopoietic cells initiates a rapidly fatal myeloproliferative disorder

Braun, B. S., Tuveson, D. A., Kong, N., Le, D. T., Kogan, S. C., Rozmus, J., Le Beau, M. M., Jacks, T. E., & Shannon, K. M. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0307203101 · Cited by 299

Activating the Expression of Human K-rasG12D Stimulates Oncogenic Transformation in Transgenic Goat Fetal

Gong, J., Wang, Z., Polejaeva, I., Salgia, R., Kao, C., Chen, T., Cells, F., Gong, J., Polejaeva, I. A., Salgia, R., et al. (2016)