Characterization and in vitro properties of potentially probiotic Bifidobacterium strains isolated from breast-milk
Abstract
Most of the current commercial probiotic strains have not been selected for specific applications, but rather on the basis of their technological potential for use in diverse applications. Therefore, by selecting them from appropriate sources, depending on the target population, it is likely that better performing strains may be identified. Few strains have been specifically selected for human neonates, where the applications of probiotics may have a great positive impact. Breast-milk constitutes an interesting source of potentially probiotic bifidobacteria for inclusion in infant formulas and foods targeted to both pre-term and full-term infants. In this study six Bifidobacterium strains isolated from breast-milk were phenotypically and genotypically characterised according to international guidelines for probiotics. In addition, different in vitro tests were used to assess the safety and probiotic potential of the strains. Although clinical data would be needed before drawing any conclusion on the probiotic properties of the strains, our results indicate that some of them may have probiotic potential for their inclusion in products targeting infants.
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Probiotics of S. salivarius CP163 and S. salivarius CP208 might play an important role in adherence to colon cancer cells as the initial appearance of probiotic action against colon cancer.
“In agreement with the results of this study, human probiotic origins were found to adhere to colon cancer cells [12,44,54], indicating that probiotics of S. salivarius CP163 and S. salivarius CP208 might play an important role in adherence to colon cancer cells as the initial appearance of probiotic action against colon cancer.”
From Bioprophylactic potential of novel human colostrum probiotics via apoptotic induction of colon cancer cells and cell immune activation (2022) · cites this paper as [54]
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- Authors
- Arboleya, S., Ruas-Madiedo, P., Margolles, A., Solís, G., Salminen, S., de los Reyes-Gavilán, C. G., & Gueimonde, M.
- Affiliations
- Consejo Superior de Investigaciones Científicas (ES)
- University of Turku (FI)
- Corresponding author
- Gueimonde, Miguel
- Venue
- International Journal of Food Microbiology
- Publisher
- Elsevier BV
- Published
- 2011-09
- Volume
- 149
- Issue
- 1
- Pages
- 28-36
- ISSN
- 0168-1605 (ISSN-L)
- OpenAlex
- W2007709006
- Cited by
- 139
- References
- 34
- Citations by year
- 2026: 1 · 2025: 12 · 2024: 10 · 2023: 3 · 2022: 13 · 2021: 11 · 2020: 12 · 2019: 8 · 2018: 11 · 2017: 9 · 2016: 8 · 2015: 12 · 2014: 7 · 2013: 10 · 2012: 9
- FWCI
- 10.72
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- International Journal of Food Microbiology (publishedVersion)
- PubMed (publishedVersion)
- DIGITAL.CSIC (Spanish National Research Council (CSIC)) (submittedVersion)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Food Science › Probiotics and Fermented Foods
- Health Sciences › Nursing › Nutrition and Dietetics › Infant Nutrition and Health
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
- Keywords
- Bifidobacterium, breast milk, probiotic potential, infant formula, neonates, preterm infants, strain characterization, probiotic strain selection
- MeSH terms
- Bacterial Adhesion, Bifidobacterium, Epithelial Cells, Female, Humans, Infant, Infant, Newborn, Intestinal Mucosa, Intestines, Milk, Human, Mucus, RNA, Bacterial, RNA, Ribosomal, 16S, Probiotics
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