Psychopathology among Offspring of Parents with Substance Abuse and/or Anxiety Disorders: A High-risk Study
Abstract
This paper reports the results of a high-risk study of children under age 18 of parents who served as probands in a family study of comorbidity of substance abuse and anxiety disorders. There was a strong degree of specificity of familial aggregation of both the anxiety disorders and substance disorders. Rates of conduct disorder and depression were elevated among offspring of all affected parents. Inclusion of co-parent disorders in the evaluation of familial transmission in the present study strengthened the findings regarding the specificity of transmission of the anxiety disorders and the links between both parental substance abuse and antisocial personality with child conduct disorder.
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Socioeconomic status and parent psychopathology have been related to SUD in offspring.
“In addition to treatment and subject characteristics, socioeconomic status and parent psychopathology have been related to SUD in offspring (34–36).”
From Age of methylphenidate treatment initiation in children with ADHD and later substance abuse: prospective follow-up into adulthood. (2008) · cites this paper as [35]
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- Authors
- Merikangas, K. R., Dierker, L. C., & Szatmari, P.
- Affiliations
- Yale University (US)
- Venue
- Journal of Child Psychology and Psychiatry
- Publisher
- Wiley
- Published
- 1998-07
- Volume
- 39
- Issue
- 5
- Pages
- 711-720
- ISSN
- 0021-9630 (ISSN-L)
- OpenAlex
- W2149867677
- Cited by
- 244
- References
- 0
- Citations by year
- 2024: 2 · 2023: 5 · 2022: 3 · 2021: 5 · 2020: 6 · 2019: 5 · 2018: 6 · 2017: 11 · 2016: 7 · 2015: 18 · 2014: 10 · 2013: 15 · 2012: 16
- FWCI
- 12.50
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Child Psychology and Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institute on Alcohol Abuse and Alcoholism (R01AA007080, AA-07080)
- National Institute of Mental Health (MH30929)
- National Institute on Drug Abuse (DA 05348)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Child and Adolescent Psychosocial and Emotional Development
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Social Sciences › Psychology › Clinical Psychology › Psychopathy, Forensic Psychiatry, Sexual Offending
- Keywords
- parental substance use, familial aggregation, conduct disorder, depression, antisocial personality, high-risk families, child psychopathology
- MeSH terms
- Adolescent, Adult, Alcoholism, Antisocial Personality Disorder, Anxiety Disorders, Child, Child Behavior Disorders, Female, Humans, Male, Personality Assessment, Psychometrics, Comorbidity, Child of Impaired Parents, Substance-Related Disorders
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