The neuropsychology of the schizo-obsessive subtype of schizophrenia: a new analysis
Open accessAbstract
Background: Interest in the neuro-cognitive profile of patients with schizophrenia and co-morbid obsessive compulsive disorder (schizo-OCD) is rising in response to reports of high co-morbidity rates. Whereas schizophrenia has been associated with global impairment in a wide range of neuro-cognitive domains, OCD is associated with specific deficits featuring impaired performance on tasks of motor and cognitive inhibition involving frontostriatal neuro-circuitry. Method: We compared cognitive function using the CANTAB battery in patients with schizo-OCD (n=12) and a schizophrenia group without OCD symptoms (n=16). The groups were matched for IQ, gender, age, medication, and duration of illness. Results: The schizo-OCD patients made significantly more errors on a task of attentional set-shifting (ID-ED set-shift task). By contrast, no significant differences emerged on the Stockings of Cambridge task, the Cambridge Gamble Task or the Affective Go/NoGo tasks. No correlation emerged between ID-ED performance and severity of schizophrenia, OCD or depressive symptoms, consistent with neurocognitive impairment holding trait rather than state-marker status. Schizo-obsessives also exhibited a trend toward more motor tics emphasizing a neurological contribution to the disorder. Conclusion: Our findings reveal a more severe attentional set-shifting deficit and neurological abnormality that may be fundamental to the neuro-cognitive profile of schizo-OCD. The clinical implications of these impairments merit further exploration in larger studies.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
OCD and schizophrenia patients may exhibit abnormal neural activities in frontostriatal and frontoparietal networks while performing tasks related to inhibition and shifting, suggesting disrupted inhibition-related and shifting-related circuitries as shared deficits across these two disorders.
“Obsessive-compulsive disorder patients and SCZ patients may exhibit abnormal neural activities in the frontostriatal (eg, cingulate cortex, dorsolateral prefrontal cortex) and frontoparietal (eg, parietal cortex) networks while performing tasks related to inhibition 26 ,29-31 and shifting, 14 ,32-35 suggesting disrupted inhibition-related and shifting-related circuitries as shared deficits across”
From Cognitive Inflexibility Shares Across Schizophrenia and Obsessive-Compulsive Disorder: A Task-Based Functional MRI Study (2025) · cites this paper as [14]
Split into 2 atoms — 0 confirmed, 2 partially supported, 0 disputed, 0 misattributed, 0 unverifiable. Expand the claim to see per-atom verdicts.
Experimental — accuracy not yet measured
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
(1998) · The Journal of Clinical Psychiatry · Cited by 19,139 · see citing works
A new depression scale designed to be sensitive to change
Montgomery, S. A., & Åsberg, M. (1979) · British Journal of Psychiatry · doi:10.1192/bjp.134.4.382 · Cited by 13,962 · see citing works
(1976) · Medical Entomology and Zoology · Cited by 8,899 · see citing works
The Yale-Brown Obsessive Compulsive Scale: I. Development, Use, and Reliability
Goodman, W. K. (1989) · Archives of General Psychiatry · doi:10.1001/archpsyc.1989.01810110048007 · Cited by 7,712 · see citing works
The mini international neuropsychiatric interview
Lecrubier, Y., Sheehan, D. V., Hergueta, T., & Weiller, E. (1998) · European Psychiatry · doi:10.1016/s0924-9338(99)80239-9 · Cited by 5,882 · see citing works
A RATING SCALE FOR EXTRAPYRAMIDAL SIDE EFFECTS
Simpson, G. M., B., M., B., G., Angus, J. W. S., P., F. R. C., & M., D. P. (1970) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.1970.tb02066.x · Cited by 3,265 · see citing works
The Yale-Brown Obsessive Compulsive Scale: II. Validity
Goodman, W. K. (1989) · Archives of General Psychiatry · doi:10.1001/archpsyc.1989.01810110054008 · Cited by 2,799 · see citing works
The Yale-Brown Obsessive-Compulsive Scale: Measures of internal consistency
Kim, S. W., Dysken, M. W., Pheley, A. M., & Hoover, K. M. (1994) · Psychiatry Research · doi:10.1016/0165-1781(94)90039-6 · Cited by 2,361 · see citing works
The yale global tic severity scale: initial testing of a clinician-rated scale of tic severity
LECKMAN, J. F., RIDDLE, M. A., HARDIN, M. T., ORT, S. I., SWARTZ, K. L., STEVENSON, J., & COHEN, D. J. (1989) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/00004583-198907000-00015 · Cited by 2,146 · see citing works
Six-Month Prevalence of Psychiatric Disorders in Three Communities
Myers, J. K. (1984) · Archives of General Psychiatry · doi:10.1001/archpsyc.1984.01790210041006 · Cited by 1,573 · see citing works
Sheehan, D. V., Harnett-Sheehan, K., & Raj, B. A. (1996) · International Clinical Psychopharmacology · doi:10.1097/00004850-199606003-00015 · Cited by 1,440 · see citing works
A short form of the metacognitions questionnaire: properties of the MCQ-30
Wells, A., & Cartwright-Hatton, S. (2004) · Behaviour Research and Therapy · doi:10.1016/s0005-7967(03)00147-5 · Cited by 1,396 · see citing works
The Epidemiology of Obsessive-Compulsive Disorder in Five US Communities
Karno, M. (1988) · Archives of General Psychiatry · doi:10.1001/archpsyc.1988.01800360042006 · Cited by 1,340 · see citing works
Rogers, R. (1999) · Neuropsychopharmacology · doi:10.1016/s0893-133x(98)00091-8 · Cited by 1,101 · see citing works
Haro, J. M., Kamath, S., Ochoa, S., Novick, D., Rele, K., Fargas, A., Rodríguez, M. J., Rele, R., Orta, J., Kharbeng, A., et al. (2003) · Acta Psychiatrica Scandinavica · doi:10.1034/j.1600-0447.107.s416.5.x · Cited by 659 · see citing works
Emotional bias and inhibitory control processes in mania and depression
MURPHY, F. C., SAHAKIAN, B. J., RUBINSZTEIN, J. S., MICHAEL, A., ROGERS, R. D., ROBBINS, T. W., & PAYKEL, E. S. (1999) · Psychological Medicine · doi:10.1017/s0033291799001233 · Cited by 659 · see citing works
Motor Inhibition and Cognitive Flexibility in Obsessive-Compulsive Disorder and Trichotillomania
Chamberlain, S. R., Fineberg, N. A., Blackwell, A. D., Robbins, T. W., & Sahakian, B. J. (2006) · American Journal of Psychiatry · doi:10.1176/ajp.2006.163.7.1282 · Cited by 627 · see citing works
Self-citationBuchanan, R. W., & Heinrichs, D. W. (1989) · Psychiatry Research · doi:10.1016/0165-1781(89)90148-0 · Cited by 594 · see citing works
Postpartum mood disorders: diagnosis and treatment guidelines.
Nonacs, R. M., & Cohen, L. S. (1998) · PubMed · Cited by 588 · see citing works
Downes, J. J., Roberts, A. C., Sahakian, B. J., Evenden, J. L., Morris, R. G., & Robbins, T. W. (1989) · Neuropsychologia · doi:10.1016/0028-3932(89)90128-0 · Cited by 527 · see citing works
A Meta-Analysis of Cognitive Deficits in Adults with a Diagnosis of Schizophrenia
Fioravanti, M., Carlone, O., Vitale, B., Cinti, M. E., & Clare, L. (2005) · Neuropsychology Review · doi:10.1007/s11065-005-6254-9 · Cited by 472 · see citing works
Chamberlain, S. R., Fineberg, N. A., Menzies, L. A., Blackwell, A. D., Bullmore, E. T., Robbins, T. W., & Sahakian, B. J. (2007) · American Journal of Psychiatry · doi:10.1176/ajp.2007.164.2.335 · Cited by 438 · see citing works
Self-citationFrontal-striatal cognitive deficits in patients with chronic schizophrenia
Pantelis, C. (1997) · Brain · doi:10.1093/brain/120.10.1823 · Cited by 430 · see citing works
Frontal-striatal dysfunction during planning in obsessive-compulsive disorder
van den Heuvel, O. A., Veltman, D. J., Groenewegen, H. J., Cath, D. C., van Balkom, A. J. L. M., van Hartskamp, J., Barkhof, F., & van Dyck, R. (2005) · Archives of General Psychiatry · doi:10.1001/archpsyc.62.3.301 · Cited by 417 · see citing works
Cortical Abnormalities in Schizophrenia Identified by Structural Magnetic Resonance Imaging
Goldstein, J. M. (1999) · Archives of General Psychiatry · doi:10.1001/archpsyc.56.6.537 · Cited by 369 · see citing works
Specific cognitive deficits in mild frontal variant frontotemporal dementia
Rahman, S., Sahakian, B. J., Hodges, J. R., Rogers, R. D., & Robbins, T. W. (1999) · Brain · doi:10.1093/brain/122.8.1469 · Cited by 369 · see citing works
Comparison of set-shifting ability in patients with chronic schizophrenia and frontal lobe damage
Pantelis, C., Barber, F. Z., Barnes, T. R. E., Nelson, H. E., Owen, A. M., & Robbins, T. W. (1999) · Schizophrenia Research · doi:10.1016/s0920-9964(98)00156-x · Cited by 347 · see citing works
Hypofrontality in schizophrenia: a meta‐analysis of functional imaging studies
Hill, K. S., Mann, L., Laws, K. R., Stephenson, C., Nimmo‐Smith, I., & McKenna, P. J. (2004) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.2004.00376.x · Cited by 333 · see citing works
Self-citationPurcell, R., Maruff, P., Kyrios, M., & Pantelis, C. (1998) · Archives of General Psychiatry · doi:10.1001/archpsyc.55.5.415 · Cited by 330 · see citing works
Fractionating Attentional Control Using Event-Related fMRI
Hampshire, A., & Owen, A. M. (2005) · Cerebral Cortex · doi:10.1093/cercor/bhj116 · Cited by 329 · see citing works
Decision-making cognition in mania and depression
MURPHY, F. C., RUBINSZTEIN, J. S., MICHAEL, A., ROGERS, R. D., ROBBINS, T. W., PAYKEL, E. S., & SAHAKIAN, B. J. (2001) · Psychological Medicine · doi:10.1017/s0033291701003804 · Cited by 316 · see citing works
Cognitive Deficits in Obsessive–Compulsive Disorder on Tests of Frontal–Striatal Function
Purcell, R., Maruff, P., Kyrios, M., & Pantelis, C. (1998) · Biological Psychiatry · doi:10.1016/s0006-3223(97)00201-1 · Cited by 313 · see citing works
The prognostic significance of obsessive-compulsive symptoms in schizophrenia
Fenton, W. S., & McGlashan, T. H. (1986) · American Journal of Psychiatry · doi:10.1176/ajp.143.4.437 · Cited by 277 · see citing works
Executive function in first-episode schizophrenia
Hutton, S. B., Puri, B. K., Duncan, L.-J., Robbins, T. W., Barnes, T. R. E., & Joyce, E. M. (1998) · Psychological Medicine · doi:10.1017/s0033291797006041 · Cited by 274 · see citing works
Neuropsychological evidence for frontostriatal dysfunction in schizophrenia
Elliott, R., McKenna, P. J., Robbins, T. W., & Sahakian, B. J. (1995) · Psychological Medicine · doi:10.1017/s0033291700033523 · Cited by 267 · see citing works
Veale, D. M., Sahakian, B. J., Owen, A. M., & Marks, I. M. (1996) · Psychological Medicine · doi:10.1017/s0033291700035984 · Cited by 239 · see citing works
A neuropsychological comparison of obsessive–compulsive disorder and trichotillomania
Chamberlain, S. R., Fineberg, N. A., Blackwell, A. D., Clark, L., Robbins, T. W., & Sahakian, B. J. (2007) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2006.07.016 · Cited by 212 · see citing works
Self-citationExecutive function in Tourette’s syndrome and obsessive–compulsive disorder
WATKINS, L. H., SAHAKIAN, B. J., ROBERTSON, M. M., VEALE, D. M., ROGERS, R. D., PICKARD, K. M., AITKEN, M. R. F., & ROBBINS, T. W. (2005) · Psychological Medicine · doi:10.1017/s0033291704003691 · Cited by 210 · see citing works
Obsessive-Compulsive Disorder in Patients With First-Episode Schizophrenia
Poyurovsky, M., Fuchs, C., & Weizman, A. (1999) · American Journal of Psychiatry · doi:10.1176/ajp.156.12.1998 · Cited by 198 · see citing works
Obsessive and compulsive symptoms in chronic schizophrenia
Berman, I., Kalinowski, A. G., Berman, S. M., Lengua, J., & Green, A. I. (1995) · Comprehensive Psychiatry · doi:10.1016/0010-440x(95)90092-a · Cited by 198 · see citing works
Computerized assessment of cognition in schizophrenia: Promises and pitfalls of CANTAB
Levaux, M., Potvin, S., Sepehry, A. A., Sablier, J., Mendrek, A., & Stip, É. (2007) · European Psychiatry · doi:10.1016/j.eurpsy.2006.11.004 · Cited by 175 · see citing works
The Clinical Significance of Obsessions in Schizophrenia
Rosen, I. (1957) · Journal of Mental Science · doi:10.1192/bjp.103.433.773 · Cited by 174 · see citing works
Obsessive–compulsive disorder in schizophrenia
Tibbo, P. G., Kroetsch, M., Chue, P. S., & Warneke, L. B. (2000) · Journal of Psychiatric Research · doi:10.1016/s0022-3956(99)00048-5 · Cited by 173 · see citing works
Montgomery, S. A. (1993) · European Neuropsychopharmacology · doi:10.1016/0924-977x(93)90266-o · Cited by 172 · see citing works
Bermanzohn, P. C., Porto, L., Arlow, P. B., Pollack, S. Z., Stronger, R., & Siris, S. G. (2000) · Schizophrenia Bulletin · doi:10.1093/oxfordjournals.schbul.a033472 · Cited by 170 · see citing works
Crino, R. D., Slade, T. N., & Andrews, G. (2005) · American Journal of Psychiatry · doi:10.1176/appi.ajp.162.5.876 · Cited by 168 · see citing works
Berman, I., Merson, A., Viegner, B., LOSONCZY, M. F., Pappas, D. M., & Green, A. I. (1998) · The Journal of Nervous and Mental Disease · doi:10.1097/00005053-199803000-00003 · Cited by 159 · see citing works
Joyce, E. M., Hutton, S. B., Mutsatsa, S., Gibbins, H., Webb, E., Paul, S., Robbins, T. W., & Barnes, T. R. E. (2002) · The British Journal of Psychiatry · doi:10.1192/bjp.181.43.s38 · Cited by 158 · see citing works
Obsessive-Compulsive Disorder in Schizophrenia
Poyurovsky, M., Weizman, A., & Weizman, R. (2004) · CNS Drugs · doi:10.2165/00023210-200418140-00004 · Cited by 157 · see citing works
Obsessive-compulsive disorder in patients with schizophrenia or schizoaffective disorder
Eisen, J. L., Beer, D. A., Pato, M. T., Venditto, T. A., & Rasmussen, S. A. (1997) · American Journal of Psychiatry · doi:10.1176/ajp.154.2.271 · Cited by 156 · see citing works
Laws, K. R. (1999) · Cognitive Neuropsychiatry · doi:10.1080/135468099396025 · Cited by 156 · see citing works
Self-citationNeurocognitive basis of impaired empathy in schizophrenia.
Shamay‐Tsoory, S., Shur, S., Harari, H., & Levkovitz, Y. (2007) · Neuropsychology · doi:10.1037/0894-4105.21.4.431 · Cited by 153 · see citing works
Obsessive–compulsive disorder in hospitalized patients with chronic schizophrenia
Poyurovsky, M., Hramenkov, S., Isakov, V., Rauchverger, B., Modai, I., Schneidman, M., Fuchs, C., & Weizman, A. (2001) · Psychiatry Research · doi:10.1016/s0165-1781(01)00238-4 · Cited by 143 · see citing works
Bland, R. C., Newman, S. C., & Orn, H. (1987) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.1987.tb02806.x · Cited by 137 · see citing works
Clinical and Neuropsychological Profiles of Obsessive-Compulsive Schizophrenia
Hwang, M. Y., Morgan, J. E., & Losconzcy, M. F. (2000) · Journal of Neuropsychiatry · doi:10.1176/jnp.12.1.91 · Cited by 137 · see citing works
Fireman, B., Koran, L. M., Leventhal, J. L., & Jacobson, A. (2001) · American Journal of Psychiatry · doi:10.1176/appi.ajp.158.11.1904 · Cited by 135 · see citing works
Anxiety and Schizophrenia: The Interaction of Subtypes of Anxiety and Psychotic Symptoms
Huppert, J. D., & Smith, T. E. (2005) · CNS Spectrums · doi:10.1017/s1092852900019714 · Cited by 133 · see citing works
Obsessive and Compulsive Symptoms in Schizophrenia
Lysaker, P. H., Marks, K. A., PICONE, J. B., Rollins, A. L., Fastenau, P. S., & Bond, G. R. (2000) · The Journal of Nervous and Mental Disease · doi:10.1097/00005053-200002000-00003 · Cited by 131 · see citing works
Öngür, D., & GOFF, D. C. (2004) · Schizophrenia Research · doi:10.1016/j.schres.2004.08.012 · Cited by 126 · see citing works
Prevalence of Obsessive-Compulsive Disorder in Schizophrenia and Significance of Motor Symptoms
Krüger, S., Bräunig, P., Höffler, J., Shugar, G., Börner, I., & Langkrär, J. (2000) · Journal of Neuropsychiatry · doi:10.1176/jnp.12.1.16 · Cited by 123 · see citing works
NIELEN, M. M. A., & DEN BOER, J. A. (2003) · Psychological Medicine · doi:10.1017/s0033291703007682 · Cited by 118 · see citing works
Obsessive-compulsive disorder: Its conceptual history in France during the 19th century
Berrios, G. E. (1989) · Comprehensive Psychiatry · doi:10.1016/0010-440x(89)90052-7 · Cited by 118 · see citing works
Intra-dimensional/extra-dimensional set-shifting performance in schizophrenia: Impact of distractors
Jazbec, S., Pantelis, C., Robbins, T. W., Weickert, T. W., Weinberger, D. R., & Goldberg, T. E. (2006) · Schizophrenia Research · doi:10.1016/j.schres.2006.08.014 · Cited by 113 · see citing works
Whitney, K. A. (2003) · Schizophrenia Research · doi:10.1016/j.schres.2003.08.013 · Cited by 111 · see citing works
Obsessive compulsive symptoms in schizophrenia: Frequency and clinical features
Byerly, M., Goodman, W. K., Acholonu, W., Bugno, R., & Rush, A. J. (2005) · Schizophrenia Research · doi:10.1016/j.schres.2005.02.004 · Cited by 110 · see citing works
Association of Obsessions and Compulsions in Schizophrenia With Neurocognition and Negative Symptoms
Lysaker, P. H., BRYSON, G. J., Marks, K. A., Greig, T. C., & Bell, M. D. (2002) · Journal of Neuropsychiatry · doi:10.1176/jnp.14.4.449 · Cited by 106 · see citing works
Set-Shifting Ability and Schizophrenia: A Marker of Clinical Illness or an Intermediate Phenotype?
Ceaser, A. E., Goldberg, T. E., Egan, M. F., McMahon, R. P., Weinberger, D. R., & Gold, J. M. (2008) · Biological Psychiatry · doi:10.1016/j.biopsych.2008.05.009 · Cited by 100 · see citing works
Specific Neuropsychological Deficits in Schizophrenic Patients with Preserved Intellectual Function
Elliott, R., McKenna, P. J., Robbins, T. W., & Sahakian, B. J. (1998) · Cognitive Neuropsychiatry · doi:10.1080/135468098396242 · Cited by 99 · see citing works
Does Obsessive-Compulsive Personality Disorder Belong Within the Obsessive-Compulsive Spectrum?
Fineberg, N. A., Sharma, P. A., Sivakumaran, T., Sahakian, B. J., & Chamberlain, S. R. (2007) · CNS Spectrums · doi:10.1017/s1092852900015340 · Cited by 93 · see citing works
Self-citationObsessive‐compulsive symptoms in schizophrenia: Prevalance and clinical correlates
Kayahan, B., Öztürk, Ö., Veznedaroğlu, B., & Eraslan, D. (2005) · Psychiatry and Clinical Neurosciences · doi:10.1111/j.1440-1819.2005.01373.x · Cited by 88 · see citing works
Decision making deficits in patients with first-episode and chronic schizophrenia
Hutton, S. B., Murphy, F. C., Joyce, E. M., Rogers, R. D., Cuthbert, I., Barnes, T. R. E., McKenna, P. J., Sahakian, B. J., & Robbins, T. W. (2002) · Schizophrenia Research · doi:10.1016/s0920-9964(01)00216-x · Cited by 83 · see citing works
Features of obsessive–compulsive disorder in patients primarily diagnosed with schizophrenia
Ohta, M., Kokai, M., & Morita, Y. (2003) · Psychiatry and Clinical Neurosciences · doi:10.1046/j.1440-1819.2003.01081.x · Cited by 76 · see citing works
Stability of set-shifting and planning abilities in patients with schizophrenia
Tyson, P. J., Laws, K. R., Roberts, K., & Mortimer, A. M. (2004) · Psychiatry Research · doi:10.1016/j.psychres.2004.09.007 · Cited by 73 · see citing works
Self-citationMukhopadhaya, K., Krishnaiah, R., Taye, T., Nigam, A., Bailey, A., Sivakumaran, T., & Fineberg, N. A. (2008) · Journal of Psychopharmacology · doi:10.1177/0269881108089582 · Cited by 72 · see citing works
Self-citationClinical profile of “schizo-obsessive” disorder: a comparative study
Rajkumar, R. P., Reddy, Y. C. J., & Thennarasu, K. (2007) · Comprehensive Psychiatry · doi:10.1016/j.comppsych.2007.09.006 · Cited by 70 · see citing works
Poyurovsky, M., Kriss, V., Weisman, G., Faragian, S., Kurs, R., Schneidman, M., Fuchs, C., Weizman, A., & Weizman, R. (2003) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v64n1104 · Cited by 70 · see citing works
Drs. Fenton and McGlashan Reply
Fenton, W. S., & McGlashan, T. H. (1986) · American Journal of Psychiatry · doi:10.1176/ajp.143.10.1323-a · Cited by 69 · see citing works
A review of antipsychotics in the treatment of obsessive compulsive disorder
Fineberg, N. A., Gale, T. M., & Sivakumaran, T. (2005) · Journal of Psychopharmacology · doi:10.1177/0269881105056640 · Cited by 61 · see citing works
Self-citationCognition in Young Schizophrenia Outpatients: Comparison of First-Episode With Multiepisode Patients
Braw, Y., Bloch, Y., Mendelovic, S., RATZONI, G., Gal, G., Harari, H., Tripto, A., & Levkovitz, Y. (2007) · Schizophrenia Bulletin · doi:10.1093/schbul/sbm115 · Cited by 61 · see citing works
Patterns of obsessive-compulsive symptoms and social function in schizophrenia
Lysaker, P. H., Lancaster, R. S., Nees, M. A., et al. (2004) · Psychiatry Research · doi:10.1016/j.psychres.2003.12.007 · Cited by 55 · see citing works
Poyurovsky, M., Isakov, V., Hromnikov, S., Modai, I., Rauchberger, B., Schneidman, M., & Weizman, A. (1999) · International Clinical Psychopharmacology · doi:10.1097/00004850-199903000-00006 · Cited by 55 · see citing works
Cognitive deficits in obsessive–compulsive disorder on tests of frontal lobe functions
Fenger, M., Gade, A., Adams, K. H., Hansen, E. S., Bolwig, T. G., & Knudsen, G. M. (2005) · Nordic Journal of Psychiatry · doi:10.1080/08039480510018814 · Cited by 54 · see citing works
Fabisch, K., Fabisch, H., Langs, G., Huber, H.-S., & Zapotoczky, H. G. (2001) · European Psychiatry · doi:10.1016/s0924-9338(01)00588-0 · Cited by 51 · see citing works
Beneficial effect of olanzapine in schizophrenic patients with obsessive-compulsive symptoms
Poyurovsky, M., Dorfman-Etrog, P., Hermesh, H., Munitz, H., Tollefson, G. D., & Weizman, A. (2000) · International Clinical Psychopharmacology · doi:10.1097/00004850-200015030-00006 · Cited by 49 · see citing works
Aoyama, F., Iida, J., Inoue, M., et al. (2000) · Acta Psychiatrica Scandinavica · doi:10.1034/j.1600-0447.2000.102001032.x · Cited by 48 · see citing works
Poyurovsky, M., Fuchs, C., Faragian, S., Kriss, V., Weisman, G., Pashinian, A., Weizman, R., & Weizman, A. (2006) · The Canadian Journal of Psychiatry · doi:10.1177/070674370605101204 · Cited by 48 · see citing works
Strategy implementation in obsessive-compulsive disorder and trichotillomania
CHAMBERLAIN, S. R., BLACKWELL, A. D., FINEBERG, N. A., ROBBINS, T. W., & SAHAKIAN, B. J. (2006) · Psychological Medicine · doi:10.1017/s0033291705006124 · Cited by 46 · see citing works
Self-citationEarly Clinical Intervention and Prevention in Schizophrenia
(2004) · Humana Press eBooks · doi:10.1007/978-1-59259-729-1 · Cited by 44 · see citing works
Clozapine-induced tardive dyskinesia: A case report
Ertuğrul, A., & Demir, B. (2005) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2005.01.014 · Cited by 39 · see citing works
Neurological Soft Signs in Schizophrenia Patients With Obsessive-Compulsive Disorder
Poyurovsky, M., Faragian, S., Pashinian, A., et al. (2007) · Journal of Neuropsychiatry · doi:10.1176/jnp.2007.19.2.145 · Cited by 35 · see citing works
Neurological soft signs in schizophrenic patients with obsessive–compulsive disorder
Sevinçok, L., Akoğlu, A., Topaloǧlu, B., et al. (2004) · Psychiatry and Clinical Neurosciences · doi:10.1111/j.1440-1819.2004.01231.x · Cited by 33 · see citing works
Dr. Eisen and Colleagues Reply
Eisen, J. L., Beer, D. A., Pato, M. T., Venditto, T. A., & Rasmussen, S. A. (1997) · American Journal of Psychiatry · doi:10.1176/ajp.154.11.1635-a · Cited by 33 · see citing works
Schizophrenia with Obsessive-Compulsive Features: Assessment and Treatment
Hwang, M. Y., & Opler, L. A. (1994) · Psychiatric Annals · doi:10.3928/0048-5713-19940901-08 · Cited by 32 · see citing works
Alternation learning in OCD/schizophrenia patients
Hermesh, H. (2003) · European Neuropsychopharmacology · doi:10.1016/s0924-977x(02)00128-1 · Cited by 31 · see citing works
Fluoxetine in Chronic Schizophrenia
Lindenmayer, J., Vakharia, M., & KANOFSKY, D. (1990) · Journal of Clinical Psychopharmacology · doi:10.1097/00004714-199002000-00031 · Cited by 31 · see citing works
Neurocognitive Deficits in the Biological Relatives of Individuals With Schizophrenia
Kremen, W., & Hoff, A. L. (2004) · Humana Press eBooks · doi:10.1007/978-1-59259-729-1_7 · Cited by 27 · see citing works
Obsessive compulsive disorder--prevalence in Xhosa-speaking schizophrenia patients.
Niehaus, D. J. H., Koen, L., Muller, J. E., et al. (2005) · PubMed · Cited by 18 · see citing works
Obsessions and Delusions: Separate and Distinct, or Overlapping?
Bermanzohn, P. C., Porto, L., Arlow, P. B., Axelrod, S., Stronger, R., Martino-beyer, J., Pollack, S. Z., & Siris, S. G. (1997) · CNS Spectrums · doi:10.1017/s1092852900004636 · Cited by 15 · see citing works
Gálvez-Buccollini, J. A., Fiestas, F., Herrera, P. M., et al. (2004) · PubMed · Cited by 12 · see citing works
Obsessive-Compulsive Disorder and Trichotillomania
Beidel, D. C., & Turner, S. (2007) · Routledge eBooks · doi:10.4324/9780203955321-17 · Cited by 6 · see citing works
Anil, A. E., Turgut, I. T., Kabakçı, E., et al. (2002) · European Neuropsychopharmacology · doi:10.1016/s0924-977x(02)80487-4 · Cited by 2 · see citing works
Neurological soft signs in schizophrenic patients
Mohr, F., Hubmann, W., Haslacher, R., et al. (1991) · Schizophrenia Research · doi:10.1016/0920-9964(91)90124-a · Cited by 2 · see citing works
Flagged first, then by citations
Research works printed but not linked: 2
- Bermanzohn PC, Porto L, Arlow PB, Pollack S, Stronger R, Siris SG (2000). Hierarchial diagnosis in chronic schizophrenia : a clinical study co-occurring syndromes. Schizophrenia Bulletin 26, 517-525.
- Bleuler E. (1911). The Fundamental Symptoms of Dementia Praecox or the Group of Schizophrenias. International Universities Press : New York.
Cited by
Sorted by citations
Neurocognitive endophenotypes of impulsivity and compulsivity: Towards dimensional psychiatry
Robbins, T. W., Gillan, C. M., Smith, D. G., de Wit, S., & Ersche, K. D. (2012) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2011.11.009 · Cited by 1,003 · see citing works
Fineberg, N. A., Chamberlain, S. R., Goudriaan, A. E., Stein, D. J., Vanderschuren, L. J. M. J., Gillan, C. M., Shekar, S., Gorwood, P. A. P. M., Voon, V., Morein-Zamir, S., et al. (2014) · CNS Spectrums · doi:10.1017/s1092852913000801 · Cited by 488 · see citing works
Self-citationCognitive inflexibility in OCD and related disorders
Chamberlain, S. R., Solly, J. E., Hook, R. W., Vaghi, M. M., & Robbins, T. W. (2021) · Current Topics in Behavioral Neurosciences · doi:10.1007/7854_2020_198 · Cited by 82 · see citing works
Schizo-obsessive spectrum disorders: an update
Scotti-Muzzi, E., & Saide, O. L. (2017) · CNS Spectrums · doi:10.1017/s1092852916000390 · Cited by 65 · see citing works
Cognitive inflexibility, obsessive-compulsive symptoms and traits and poor post-pandemic adjustment
Frota Lisboa Pereira de Souza, A. M., Pellegrini, L., & Fineberg, N. A. (2024) · Neuroscience Applied · doi:10.1016/j.nsa.2024.104073 · Cited by 8 · see citing works
Self-citationChu, M.-Y., Li, S.-B., Zhang, Y., Wang, L.-L., Lv, Q.-Y., Lui, S. S. Y., Wang, Z., Yi, Z.-H., Wang, Y., & Chan, R. C. K. (2025) · Schizophrenia Bulletin · doi:10.1093/schbul/sbaf220 · Cited by 2 · see citing works
- Authors
- Patel, D. D., Laws, K. R., Padhi, A., Farrow, J. M., Mukhopadhaya, K., Krishnaiah, R., & Fineberg, N. A.
- Affiliations
- University of Hertfordshire (GB)
- Queen Elizabeth II Hospital (GB)
- Corresponding author
- Laws, K. R.
- Venue
- Psychological Medicine
- Publisher
- Cambridge University Press (CUP)
- Published
- 2009-10-12
- Volume
- 40
- Issue
- 6
- Pages
- 921-933
- ISSN
- 0033-2917 (ISSN-L)
- 1469-8978
- OpenAlex
- W2163955534
- Cited by
- 82
- References
- 102
- Citations by year
- 2025: 3 · 2024: 4 · 2023: 2 · 2022: 4 · 2021: 3 · 2020: 2 · 2019: 4 · 2018: 4 · 2017: 3 · 2016: 6 · 2015: 11 · 2014: 12 · 2013: 8 · 2012: 5
- FWCI
- 3.29
- Type
- journal article
- Language
- en
- Open access
- green
- hdl.handle.net
- Locations
- Psychological Medicine (publishedVersion)
- PubMed (publishedVersion)
- University of Hertfordshire Research Archive (University of Hertfordshire) (submittedVersion)
- Funders
- University of Hertfordshire
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
- Social Sciences › Psychology › Clinical Psychology › Obsessive-Compulsive Spectrum Disorders
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
- Keywords
- schizo-obsessive disorder, schizophrenia, obsessive-compulsive disorder, comorbidities, neurocognitive impairment, set-shifting, inhibitory control, frontostriatal circuits, motor tics, neuropsychology, CANTAB
- MeSH terms
- Adult, Affect, Aged, Attention, Corpus Striatum, Diagnosis, Differential, Discrimination, Psychological, Female, Frontal Lobe, Humans, Male, Middle Aged, Nerve Net, Neuropsychological Tests, Obsessive-Compulsive Disorder, Psychiatric Status Rating Scales, Psychomotor Performance, Reaction Time, Schizophrenia, Schizophrenic Psychology, Semantics, Comorbidity, Diagnosis, Dual (Psychiatry), Young Adult, Executive Function
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
