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Cognitive impairment in euthymic major depressive disorder: a meta-analysis
Open accessAbstract
Background: There is evidence to suggest that cognitive deficits might persist beyond the acute stages of illness in major depressive disorder (MDD). However, the findings are somewhat inconsistent across the individual studies conducted to date. Our aim was to conduct a systematic review and meta-analysis of existing studies that have examined cognition in euthymic MDD patients. Method: Following a systematic search across several publication databases, meta-analyses were conducted for 27 empirical studies that compared euthymic adult MDD patients (895 participants) and healthy controls (997 participants) across a range of cognitive domains. The influence of demographic variables and confounding factors, including age of onset and recurrent episodes, was examined. Results: Compared with healthy controls, euthymic MDD patients were characterized by significantly poorer cognitive functions. However, the magnitude of observed deficits, with the exception of inhibitory control, were generally modest when late-onset cases were excuded. Late-onset cases demonstrated significantly more pronounced deficits in verbal memory, speed of information processing and some executive functions. Conclusions: Cognitive deficits, especially poor response inhibition, are likely to be persistent features, at least of some forms, of adult-onset MDD. More studies are necessary to examine cognitive dysfunction in remitted psychotic, melancholic and bipolar spectrum MDD. Cognitive deficits overall appear to be more common among patients with late-onset depression, supporting the theories suggesting that possible vascular and neurodegenerative factors play a role in a substantial number of these patients.
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“Many patients suffering from MDD present some form of dysfunction in certain cognitive domains; this affects >60% of all depressed patients and significantly impacts treatment outcomes (Bora et al, 2013; Gualtieri and Morgan, 2008; Lee et al, 2012; Murrough et al, 2011; Rock et al, 2014; Trivedi and Greer, 2014).”
From A Randomized, Placebo-Controlled, Active-Reference, Double-Blind, Flexible-Dose Study of the Efficacy of Vortioxetine on Cognitive Function in Major Depressive Disorder (2015) · cites this paper as Bora et al, 2013
Experimental — accuracy not yet measuredThe source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
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“Several cognitive domains, including executive function, attention, memory, processing speed, and psychomotor skills, are affected during both symptomatic as well as “remitted” phases in MDD (Marazziti et al., 2010; Lee et al., 2012; Bora et al., 2013; Bortolato et al., 2014).”
From The Cognitive Effects of Antidepressants in Major Depressive Disorder: A Systematic Review and Meta-Analysis of Randomized Clinical Trials (2016) · cites this paper as Bora et al., 2013
Experimental — accuracy not yet measuredThe source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
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“Although some have demonstrated that individuals experiencing depression perform worse across all neurocognitive domains (e.g., Bora et al., 2013;Parkinson et al., 2020), evidence varies regarding the domain most impacted by depression across the lifespan and include executive function (Alexopoulos, 2021), processing speed (Göke et al., 2024), and verbal memory (Bora et al., 2013;Goodall et al., 2”
From Neurocognitive effects of theta burst stimulation for treatment-resistant depression in adults: A systematic review and recommendations for future research (2025) · cites this paper as Bora et al., 2013
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“Finally, a meta-analysis of 27 studies investigating euthymic adult subjects with MDD showed that executive dysfunction (namely lower inhibitory control) could persist after improvement of depressive symptoms [39].”
From Cognitive remission: a novel objective for the treatment of major depression? (2016) · cites this paper as [39]
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“Mood disorders are also associated with impairments in cognitive functioning.”
From A Randomized, Placebo-Controlled, Active-Reference, Double-Blind, Flexible-Dose Study of the Efficacy of Vortioxetine on Cognitive Function in Major Depressive Disorder (2015) · cites this paper as Bora et al, 2013
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“Neurocognitive dysfunction is commonly reported during depressive episodes and even during remission (Bora et al., 2013;Conradi et al., 2011;Hasselbalch et al., 2011).”
From Neurocognitive effects of theta burst stimulation for treatment-resistant depression in adults: A systematic review and recommendations for future research (2025) · cites this paper as Bora et al., 2013
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“As cognitive dysfunction is a core symptom of depression that can persist during the remitted state (Bora et al., 2013;Hasselbalch et al., 2011;Kaser et al., 2017), worsens with increasing numbers of depressive episodes (Hasselbalch et al., 2013), and results in disrupted psychosocial functioning (Hasselbalch et al., 2011;Kaser et al., 2017;McCall and Dunn, 2003)”
From Neurocognitive effects of theta burst stimulation for treatment-resistant depression in adults: A systematic review and recommendations for future research (2025) · cites this paper as Bora et al., 2013
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“As pointed out by Fitzgerald 195 , DBS is typically reserved for patients with the most severe forms of TRD”
From Major depressive disorder (2016) · cites this paper as [195]
Experimental — accuracy not yet measuredIn the citing paper
“Even after remission following successful antidepressant treatment, most patients continue to experience cognitive deficits, particularly within domains of executive function, memory, and attention (Hammar and Ardal, 2009; Bora et al., 2013; Rock et al., 2013; Popovic et al., 2015; Solé et al., 2015).”
From Aerobic Exercise as a Tool to Improve Hippocampal Plasticity and Function in Humans: Practical Implications for Mental Health Treatment (2016) · cites this paper as Bora et al., 2013
In the citing paper
“Moreover, these analyses noted an effect of age as a correlate of poor cognitive performance in MDD, introducing disparate etiopathogenic mechanisms (e.g. vascular and neurodegenerative factors).”
From Cognitive remission: a novel objective for the treatment of major depression? (2016) · cites this paper as [39]
In the citing paper
“Subjects with late-onset depression (i.e. >60 years old) are likely to experience increased impairment in verbal memory, processing speed, and executive function with respect to depressed adults [39].”
From Cognitive remission: a novel objective for the treatment of major depression? (2016) · cites this paper as [39]
In the citing paper
“Cognitive symptoms are seen in first-episode depression [6,8], persist beyond the symptoms of low mood [9-11], contribute to the risk of relapse [12], and worsen with repeated depressive episodes [13,14].”
From Wearable technology for high-frequency cognitive and mood assessment in major depressive disorder: longitudinal observational study (2019) · cites this paper as [11]
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Citations
Cites
Preferred Reporting Items for Systematic Reviews and Meta-Analyses: the PRISMA statement
Moher, D., Liberati, A., Tetzlaff, J., Altman, D. G., & for the PRISMA Group (2009) · BMJ · doi:10.1136/bmj.b2535 · Cited by 83,823
Preferred reporting items for systematic reviews and meta-analyses: the PRISMA Statement.
(2009) · PubMed Central · Cited by 44,859
Quantifying heterogeneity in a meta‐analysis
Higgins, J. P. T., & Thompson, S. G. (2002) · Statistics in Medicine · doi:10.1002/sim.1186 · Cited by 36,763
Lower Hippocampal Volume in Patients Suffering From Depression: A Meta-Analysis
Campbell, S., Marriott, M., Nahmias, C., & MacQueen, G. M. (2004) · American Journal of Psychiatry · doi:10.1176/appi.ajp.161.4.598 · Cited by 1,156
Bora, E., Yücel, M., & Pantelis, C. (2008) · Journal of Affective Disorders · doi:10.1016/j.jad.2008.06.009 · Cited by 1,058
Self-citationA meta-analysis of depression severity and cognitive function
McDermott, L. M., & Ebmeier, K. P. (2009) · Journal of Affective Disorders · doi:10.1016/j.jad.2009.04.022 · Cited by 956
Bora, E., Fornito, A., Pantelis, C., & Yücel, M. (2012) · Journal of Affective Disorders · doi:10.1016/j.jad.2011.03.049 · Cited by 763
Self-citationA meta-analysis of cognitive deficits in first-episode Major Depressive Disorder
Lee, R. S. C., Hermens, D. F., Porter, M. A., & Redoblado-Hodge, M. A. (2012) · Journal of Affective Disorders · doi:10.1016/j.jad.2011.10.023 · Cited by 737
Bax, L., Yu, L.-M., Ikeda, N., Tsuruta, H., & Moons, K. G. (2006) · BMC Medical Research Methodology · doi:10.1186/1471-2288-6-50 · Cited by 514
Attention and executive functions in remitted major depression patients
Paelecke-Habermann, Y., Pohl, J., & Leplow, B. (2005) · Journal of Affective Disorders · doi:10.1016/j.jad.2005.09.006 · Cited by 487
A Functional Magnetic Resonance Imaging Study of Bipolar Disorder
Blumberg, H. P., Leung, H., Skudlarski, P., Lacadie, C., Fredericks, C. A., Harris, B. C., Charney, D. S., Gore, J. C., Krystal, J. H., & Peterson, B. S. (2003) · Archives of General Psychiatry · doi:10.1001/archpsyc.60.6.601 · Cited by 479
Cognitive performance in tests sensitive to frontal lobe dysfunction in the elderly depressed
Beats, B. C., Sahakian, B. J., & Levy, R. (1996) · Psychological Medicine · doi:10.1017/s0033291700035662 · Cited by 457
White matter hyperintensities in late life depression: a systematic review
Herrmann, L. L., Le Masurier, M., & Ebmeier, K. P. (2007) · Journal of Neurology, Neurosurgery & Psychiatry · doi:10.1136/jnnp.2007.124651 · Cited by 456
O'Brien, J. T. (2004) · American Journal of Psychiatry · doi:10.1176/appi.ajp.161.11.2081 · Cited by 409
Cognitive impairment in the remitted state of unipolar depressive disorder: A systematic review
Hasselbalch, B. J., Knorr, U., & Kessing, L. V. (2011) · Journal of Affective Disorders · doi:10.1016/j.jad.2010.11.011 · Cited by 406
Voxelwise Meta-Analysis of Gray Matter Abnormalities in Bipolar Disorder
Bora, E., Fornito, A., Yücel, M., & Pantelis, C. (2010) · Biological Psychiatry · doi:10.1016/j.biopsych.2010.01.020 · Cited by 378
Self-citationEvidence for continuing neuropsychological impairments in depression
Weiland-Fiedler, P., Erickson, K., Waldeck, T., Luckenbaugh, D. A., Pike, D., Bonne, O., Charney, D. S., & Neumeister, A. (2004) · Journal of Affective Disorders · doi:10.1016/j.jad.2003.10.009 · Cited by 314
Cognitive function in depression: a distinct pattern of frontal impairment in melancholia?
Austin, M., Mitchell, P. B., Wilhelm, K. A., Parker, G. B., Hickie, I. B., Brodaty, H., CHAN, J., Eyers, K., MILIC, M., & Hadži-Pavlović, D. (1999) · Psychological Medicine · doi:10.1017/s0033291798007788 · Cited by 298
Persistence of Neuropsychologic Deficits in the Remitted State of Late-Life Depression
Bhalla, R. K., Butters, M. A., Mulsant, B. H., Begley, A. E., Zmuda, M. D., Schoderbek, B., Pollock, B. G., Reynolds, C. F., & Becker, J. T. (2006) · The American Journal of Geriatric Psychiatry · doi:10.1097/01.jgp.0000203130.45421.69 · Cited by 292
Bora, E., Harrison, B. J., Davey, C. G., Yücel, M., & Pantelis, C. (2012) · Psychological Medicine · doi:10.1017/s0033291711001668 · Cited by 276
Self-citationGorwood, P. A. P. M., Corruble, E., Falissard, B., & Goodwin, G. M. (2008) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2008.07040574 · Cited by 265
The cognitive neuropsychology of depression in the elderly
Herrmann, L. L., Goodwin, G. M., & Ebmeier, K. P. (2007) · Psychological Medicine · doi:10.1017/s0033291707001134 · Cited by 250
Li, C., Lin, C., Chou, K., Chen, I.-Y., Hsieh, J., Wu, C., Lin, W.-C., & Su, T. (2009) · NeuroImage · doi:10.1016/j.neuroimage.2009.11.021 · Cited by 220
Trichard, C., Martinot, J. L., Alagille, M., Masure, M. C., Hardy, P., Ginestet, D., & Féline, A. (1995) · Psychological Medicine · doi:10.1017/s0033291700028105 · Cited by 220
Clark, L., Sarna, A., & Goodwin, G. M. (2005) · American Journal of Psychiatry · doi:10.1176/appi.ajp.162.10.1980 · Cited by 203
Xu, G., Lin, K., Rao, D., Dang, Y., Ouyang, H., Guo, Y., Ma, J., & Chen, J. (2011) · Journal of Affective Disorders · doi:10.1016/j.jad.2011.11.029 · Cited by 193
Clark, L., Kempton, M. J., Scarnà, A., Grasby, P. M., & Goodwin, G. M. (2005) · Biological Psychiatry · doi:10.1016/j.biopsych.2004.11.007 · Cited by 174
Frontostriatal deficits in unipolar major depression
Rogers, M. A., Bradshaw, J. L., Pantelis, C., & Phillips, J. G. (1998) · Brain Research Bulletin · doi:10.1016/s0361-9230(98)00126-9 · Cited by 150
Self-citationCognitive Impairment in Affective Psychoses: A Meta-analysis
Bora, E., Yücel, M., & Pantelis, C. (2009) · Schizophrenia Bulletin · doi:10.1093/schbul/sbp093 · Cited by 131
Self-citationYuan, Y., Zhang, Z., Bai, F., Yu, H., Shi, Y., Qian, Y., Liu, W., You, J., Zhang, X., & Liu, Z. (2008) · Journal of Affective Disorders · doi:10.1016/j.jad.2008.02.016 · Cited by 127
Cognitive deficits in the euthymic phase of unipolar depression
Preiss, M., Kucerova, H., Lukavsky, J., Stepankova, H., Sos, P., & Kawaciukova, R. (2009) · Psychiatry Research · doi:10.1016/j.psychres.2008.06.042 · Cited by 127
Memory impairment in patients with late-onset major depression: The effect of antidepressant therapy
Gallassi, R., Di Sarro, R., Morreale, A., & Amore, M. (2006) · Journal of Affective Disorders · doi:10.1016/j.jad.2006.01.018 · Cited by 118
Executive dysfunction in medicated, remitted state of major depression
Nakano, Y., Baba, H., Maeshima, H., Kitajima, A., Sakai, Y., Baba, K., Suzuki, T., Mimura, M., & Arai, H. (2008) · Journal of Affective Disorders · doi:10.1016/j.jad.2008.01.027 · Cited by 114
Ficek, S. K., Blasey, C. M., & Schatzberg, A. F. (2003) · Journal of Psychiatric Research · doi:10.1016/s0022-3956(03)00100-6 · Cited by 104
A longitudinal analysis of neurocognitive function in unipolar depression
Biringer, E., Mykletun, A., Sundet, K. S., Kroken, R. A., Stordal, K. I., & Lund, A. (2007) · Journal of Clinical and Experimental Neuropsychology · doi:10.1080/13803390601147686 · Cited by 96
Herrera-Guzmán, I., Gudayol-Ferré, E., Herrera-Abarca, J. E., Herrera-Guzmán, D., Montelongo-Pedraza, P., Padrós Blázquez, F., Peró-Cebollero, M., & Guàrdia-Olmos, J. (2010) · Journal of Affective Disorders · doi:10.1016/j.jad.2009.10.009 · Cited by 94
Striatal structure and function in mood disorders: a comprehensive review
Marchand, W. R., & Yurgelun‐Todd, D. (2010) · Bipolar Disorders · doi:10.1111/j.1399-5618.2010.00874.x · Cited by 91 · cited 1×
“These pronounced deficits might be related to progressive abnormalities in cortico-striatal-pallidal-thalamic circuits that have been identified in MDD (Rogers et al. 1998 ; Marchand & Yurgelun-Todd, 2010; Bora et al. 2012b) as well as vascular changes in white matter (Herrmann et al. 2008).”
BackgroundDepressive Symptoms Impair Everyday Problem-Solving Ability Through Cognitive Abilities in Late Life
Yen, Y., Rebok, G. W., Gallo, J. J., Jones, R. N., & Tennstedt, S. L. (2010) · American Journal of Geriatric Psychiatry · doi:10.1097/jgp.0b013e3181e89894 · Cited by 86
Hartberg, C. B., Sundet, K. S., Rimol, L. M., Haukvik, U. K., Lange, E. H., Nesvåg, R., Melle, I. S., Andreassen, O. A., & Agartz, I. (2011) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2011.03.014 · Cited by 79
Persistent non-verbal memory impairment in remitted major depression — Caused by encoding deficits?
Behnken, A., Schöning, S., Gerß, J., Konrad, C., de Jong-Meyer, R., Zwanzger, P., & Arolt, V. (2010) · Journal of Affective Disorders · doi:10.1016/j.jad.2009.07.010 · Cited by 79
Anterior cingulate subregion volumes and executive function in bipolar disorder
Zimmerman, M. E., DelBello, M. P., Getz, G. E., Shear, P. K., & Strakowski, S. M. (2006) · Bipolar Disorders · doi:10.1111/j.1399-5618.2006.00298.x · Cited by 69
Verbal memory performance of mildly to moderately depressed outpatient younger adults
Wang, C. E., Halvorsen, M. B., Sundet, K. S., Steffensen, A. L., Holte, A., & Waterloo, K. K. (2006) · Journal of Affective Disorders · doi:10.1016/j.jad.2006.02.008 · Cited by 67
Residual cognitive impairment in late‐life depression after a 12‐month period follow‐up
Portella, M. J., Marcos, T., Rami, L., Navarro, V., Gastó, C., & Salamero, M. (2003) · International Journal of Geriatric Psychiatry · doi:10.1002/gps.895 · Cited by 67
Time-related cognitive deficiency in four different types of depression
Neu, P., Kiesslinger, U., Schlattmann, P., & Reischies, F. M. (2001) · Psychiatry Research · doi:10.1016/s0165-1781(01)00286-4 · Cited by 64
Depression subtypes and 5‐year risk of dementia and Alzheimer disease in patients aged 70 years
Franch, J. V., Pousa, S. L., Reglà, J. L., Calvó‐Perxas, L., Merino‐Aguado, J., & Garre‐Olmo, J. (2012) · International Journal of Geriatric Psychiatry · doi:10.1002/gps.3826 · Cited by 60
Subtypes of Mild Cognitive Impairment Among the Elderly With Major Depressive Disorder in Remission
Yeh, Y., Tsang, H., Lin, P., Kuo, Y., Yen, C., Chen, C., Liu, G., & Chen, C. (2010) · American Journal of Geriatric Psychiatry · doi:10.1097/jgp.0b013e318202clc6 · Cited by 58
Cognitive Deficits in Euthymic Patients With Recurrent Depression
Bhardwaj, A., Wilkinson, P. O., Srivastava, C., & Sharma, M. (2010) · The Journal of Nervous and Mental Disease · doi:10.1097/nmd.0b013e3181e4c5ba · Cited by 51
Delaloye, C., Moy, G., de Bilbao, F., Baudois, S., Weber, K., Hofer, F., Paquier, C. R., Donati, A., Canuto, A., Giardini, U., et al. (2010) · Journal of the Neurological Sciences · doi:10.1016/j.jns.2010.08.046 · Cited by 50
Longitudinal changes in hippocampal volumes and cognition in remitted geriatric depressive disorder
Hou, Z., Yuan, Y., Zhang, Z., Bai, F., Hou, G., & You, J. (2011) · Behavioural Brain Research · doi:10.1016/j.bbr.2011.10.025 · Cited by 42
Fennig, S., MOTTES, A., RICTER-LEVIN, G., Treves, I., & Levkovitz, Y. (2002) · The Journal of Nervous and Mental Disease · doi:10.1097/00005053-200210000-00004 · Cited by 33
Kaneda, Y. (2009) · Clinical Neuropharmacology · doi:10.1097/wnf.0b013e3181b130a0 · Cited by 22
Implicit and explicit procedural learning in patients recently remitted from severe major depression
Pedersen, A., Kueppers, K. A., Behnken, A., Kroker, K., Schöning, S., Baune, B. T., Rist, F., Arolt, V., & Suslow, T. (2009) · Psychiatry Research · doi:10.1016/j.psychres.2008.06.001 · Cited by 21
Depression subtypes and 5‐years risk of mortality in aged 70 years: a population‐based cohort study
Franch, J. V., Pujol, X. P., Pousa, S. L., Reglà, J. L., Merino‐Aguado, J., & Garre‐Olmo, J. (2011) · International Journal of Geriatric Psychiatry · doi:10.1002/gps.2691 · Cited by 19
Baba, K., Baba, H., Noguchí, I., Arai, R., Suzuki, T., Mimura, M., & Arai, H. (2010) · Journal of Neuropsychiatry · doi:10.1176/jnp.2010.22.1.70 · Cited by 19
Huang, C. L.-C. (2009) · Journal of Clinical Medicine Research · doi:10.4021/jocmr2009.10.1266 · Cited by 13
Research works printed but not linked: 1
- Jaracz, 2002, Cognitive functions in remitted unipolar female depressive patients during maintenance treatment with antidepressants, Archives of Psychiatry and Psychotherapy, 4, 15
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Rock, P. L., Roiser, J. P., Riedel, W. J., & Blackwell, A. D. (2014) · Psychological Medicine · doi:10.1017/s0033291713002535 · Cited by 2,161
Malhi, G. S., Bassett, D., Boyce, P., Bryant, R., Fitzgerald, P. B., Fritz, K., Hopwood, M., Lyndon, B., Mulder, R., Murray, G., et al. (2015) · Australian & New Zealand Journal of Psychiatry · doi:10.1177/0004867415617657 · Cited by 842
“This is the case in both unipolar depression (Bora et al., 2013) and bipolar disorder (Baune and Malhi, 2015; Bourne et al.”
BackgroundCognitive function following a major depressive episode: a systematic review and meta-analysis
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Metadata
- Authors
- Bora, E., Harrison, B. J., Yücel, M., & Pantelis, C.
- Affiliations
- The University of Melbourne (AU)
- Corresponding author
- Bora, E.
- Venue
- Psychological Medicine
- Publisher
- Cambridge University Press (CUP)
- Published
- 2012-10-26
- Volume
- 43
- Issue
- 10
- Pages
- 2017-2026
- ISSN
- 0033-2917 (ISSN-L)
- 1469-8978
- OpenAlex
- W2020449419
- Cited by
- 551
- References
- 56
- Citations by year
- 2026: 31 · 2025: 38 · 2024: 32 · 2023: 42 · 2022: 57 · 2021: 51 · 2020: 50 · 2019: 51 · 2018: 50 · 2017: 37 · 2016: 44 · 2015: 41 · 2014: 15 · 2013: 11 · 2012: 1
- FWCI
- 2.49
- Type
- journal article
- Language
- en
- Open access
- green
- hdl.handle.net
- Locations
- Psychological Medicine (publishedVersion)
- PubMed (publishedVersion)
- Minerva Access (University of Melbourne) (submittedVersion)
- Funders
- National Alliance for Research on Schizophrenia and Depression
- Medical Research Council
- National Health and Medical Research Council (628509, 1021973, 566529, 628386)
- Topics
- Health Sciences › Medicine › Pharmacology (medical) › Treatment of Major Depression
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Keywords
- major depressive disorder, cognitive impairment, late-onset depression, response inhibition, verbal memory, processing speed, executive function, age of onset, recurrent depression
- MeSH terms
- Cognition Disorders, Major Depressive Disorder, Depressive Disorder, Major, Humans
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