Cited by 57Anxiety, Depression, Psychometrics, Treatment, Cognitive ProcessesSubstance Abuse Treatment and OutcomesPersonality Disorders and Psychopathology

The Role of Negative Emotionality and Impulsivity in Depressive/Anxiety Disorders and Alcohol Dependence

Boschloo, L., Vogelzangs, N., van den Brink, W., Smit, J. H., Beekman, A. T. F., Penninx, B. W. J. H.·2013·Psychological Medicine

Abstract

BACKGROUND: Much is still unclear about the role of personality in the structure of common psychiatric disorders such as depressive/anxiety disorders and alcohol dependence. This study will therefore examine whether various traits of negative emotionality and impulsivity showed shared or specific associations with these disorders. Method Cross-sectional data were used from the Netherlands Study of Depression and Anxiety (NESDA), including individuals with no DSM-IV psychiatric disorder (n = 460), depressive/anxiety disorder only (i.e. depressive and/or anxiety disorder; n = 1398), alcohol dependence only (n = 32) and co-morbid depressive/anxiety disorder plus alcohol dependence (n = 358). Aspects of negative emotionality were neuroticism, hopelessness, rumination, worry and anxiety sensitivity, whereas aspects of impulsivity included disinhibition, thrill/adventure seeking, experience seeking and boredom susceptibility. RESULTS: Aspects of negative emotionality formed a homogeneous dimension, which was unrelated to the more heterogeneous construct of impulsivity. Although all aspects of negative emotionality were associated with alcohol dependence only, associations were much stronger for depressive/anxiety disorder only and co-morbid depressive/anxiety disorder with alcohol dependence. The results for impulsivity traits were less profound and more variable, with disinhibition and boredom susceptibility showing modest associations with both depressive/anxiety disorder and alcohol dependence, whereas low thrill/adventure seeking and high disinhibition were more strongly related with the first and the latter, respectively. CONCLUSIONS: Our results suggest that depressive/anxiety disorder and alcohol dependence result from shared as well as specific aetiological pathways as they showed the same associations with all aspects of negative emotionality, disinhibition and boredom susceptibility as well as specific associations with thrill/adventure seeking and disinhibition.

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Crossref · 10.1017/s0033291712002152

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Authors
Boschloo, L., Vogelzangs, N., van den Brink, W., Smit, J. H., Beekman, A. T. F., & Penninx, B. W. J. H.
Affiliations
  • University Medical Center Groningen (NL)
  • Amsterdam Public Health (NL)
Corresponding author
Boschloo, L.
Venue
Psychological Medicine
Published
2012-10-01
Volume
43
Issue
6
Pages
1241-1253
ISSN
  • 0033-2917 (ISSN-L)
  • 1469-8978
OpenAlex
W2063184400
Cited by
57
References
54
Citations by year
2026: 5 · 2025: 2 · 2024: 2 · 2023: 3 · 2022: 5 · 2021: 5 · 2020: 6 · 2019: 6 · 2018: 4 · 2017: 5 · 2016: 7 · 2015: 3 · 2014: 2 · 2013: 2
FWCI
3.00
Type
journal article
Language
en
Open access
closed
Locations
  • Psychological Medicine (publishedVersion)
  • PubMed (publishedVersion)
  • Amsterdam UMC (VU Amsterdam) - Institutional Repository (publishedVersion)
  • University of Groningen research database (University of Groningen / Centre for Information Technology) (publishedVersion)
  • Data Archiving and Networked Services (DANS) (submittedVersion)
  • Leiden Repository (Leiden University) (submittedVersion)
  • Pure Amsterdam UMC (submittedVersion)
  • VU Research Portal (submittedVersion)
  • University of Groningen research database (University of Groningen / Centre for Information Technology) (submittedVersion)
Funders
  • World Health Organization
  • GGZ Drenthe
Topics
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
  • Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
  • Social Sciences › Psychology › Clinical Psychology › Personality Disorders and Psychopathology
Keywords
negative affectivity, impulsivity, depressive disorders, anxiety disorders, alcoholism, personality traits, neuroticism, hopelessness, rumination, worry, anxiety sensitivity, disinhibition, boredom susceptibility, sensation seeking, experience seeking, comorbidities
MeSH terms
Neuroticism, Adolescent, Adult, Aged, Alcoholism, Anxiety Disorders, Cross-Sectional Studies, Major Depressive Disorder, Depressive Disorder, Emotions, Female, Humans, Impulsive Behavior, Male, Middle Aged, Netherlands, Personality, Cohort Studies, Comorbidity, Young Adult

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