The DOI matches its Crossref record; 31 of the 31 references it cites were found in a registry or an index.
The global burden of anxiety disorders in 2010
Abstract
Background: Despite their high prevalence, the global burden of anxiety disorders has never been calculated comprehensively. The new Global Burden of Disease (GBD) study has estimated burden due to morbidity and mortality caused by any anxiety disorder. Method: Prevalence was estimated using Bayesian meta-regression informed by data identified in a systematic review. Years of life lived with disability (YLDs) were calculated by multiplying prevalent cases by an average disability weight based on severity proportions (mild, moderate and severe). Disability-adjusted life years (DALYs) were then calculated and age standardized using global standard population figures. Estimates were also made for additional suicide mortality attributable to anxiety disorders. Findings are presented for YLDs, DALYs and attributable burden due to suicide for 21 world regions in 1990 and 2010. Results: Anxiety disorders were the sixth leading cause of disability, in terms of YLDs, in both high-income (HI) and low- and middle-income (LMI) countries. Globally, anxiety disorders accounted for 390 DALYs per 100 000 persons [95% uncertainty interval (UI) 191–371 DALYs per 100 000] in 2010, with no discernible change observed over time. Females accounted for about 65% of the DALYs caused by anxiety disorders, with the highest burden in both males and females experienced by those aged between 15 and 34 years. Although there was regional variation in prevalence, the overlap between uncertainty estimates means that substantive differences in burden between populations could not be identified. Conclusions: Anxiety disorders are chronic, disabling conditions that are distributed across the globe. Future estimates of burden could be further improved by obtaining more representative data on severity state proportions.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“In particular, depression and anxiety are leading causes of reduced quality of life among children and adolescents [4–8].”
From Psychological impacts of “screen time” and “green time” for children and adolescents: A systematic scoping review (2020) · cites this paper as [8]
In the citing paper
“Experiences of depressive and anxiety symptoms in childhood and adolescence are associated with an elevated risk of poor mental health in adulthood [8–12]”
From Psychological impacts of “screen time” and “green time” for children and adolescents: A systematic scoping review (2020) · cites this paper as [8]
In the citing paper
“Direct and indirect costs of depression and anxiety make these disorders main contributors to the global burden of disease [42, 43]”
From Mobile Apps for the Management of Comorbid Overweight/Obesity and Depression/Anxiety: A Systematic Review (2020) · cites this paper as [42]
In the citing paper
“Anxiety disorders are common, burdensome and costly to individuals and wider society.”
From Moving to Beat Anxiety: Epidemiology and Therapeutic Issues with Physical Activity for Anxiety (2018) · cites this paper as [4]
Citations
Cites
Preferred Reporting Items for Systematic Reviews and Meta-Analyses: the PRISMA statement
Moher, D., Liberati, A., Tetzlaff, J., Altman, D. G., & for the PRISMA Group (2009) · BMJ · doi:10.1136/bmj.b2535 · Cited by 83,823
Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement
Moher, D., Liberati, A., Tetzlaff, J., Altman, D. G., & The PRISMA Group (2009) · PLoS Medicine · doi:10.1371/journal.pmed.1000097 · Cited by 64,042
Preferred reporting items for systematic reviews and meta-analyses: the PRISMA Statement.
(2009) · PubMed Central · Cited by 44,859
Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement
Moher, D., Liberati, A., Tetzlaff, J., & Altman, D. G. (2009) · Journal of Clinical Epidemiology · doi:10.1016/j.jclinepi.2009.06.005 · Cited by 19,575
Lim, S. S., Vos, T., Flaxman, A. D., Danaei, G., Shibuya, K., Adair-Rohani, H., AlMazroa, M. A., Amann, M., Anderson, H. R., Andrews, K. G., et al. (2012) · The Lancet · doi:10.1016/s0140-6736(12)61766-8 · Cited by 11,805
Self-citationVos, T., Flaxman, A. D., Naghavi, M., Lozano, R., Michaud, C., Ezzati, M., Shibuya, K., Salomon, J. A., Abdalla, S., Aboyans, V., et al. (2012) · The Lancet · doi:10.1016/s0140-6736(12)61729-2 · Cited by 8,291
Self-citation(1996) · Cited by 6,884
Whiteford, H. A., Degenhardt, L., Rehm, J., Baxter, A. J., Ferrari, A. J., Erskine, H. E., Charlson, F. J., Norman, R. E., Flaxman, A. D., Johns, N., et al. (2013) · The Lancet · doi:10.1016/s0140-6736(13)61611-6 · Cited by 6,006
Self-citation(2004) · JAMA · doi:10.1001/jama.291.21.2581 · Cited by 3,448 · cited 1×
“Several surveys have shown that most people experiencing an anxiety disorder do not seek treatment, particularly those with less severe symptoms (Demyttenaere et al. 2004).”
Background(2007) · PubMed Central · Cited by 2,521
Research works printed but not linked: 10
- Ayuso-Mateos, 2006, Global Burden of Post-Traumatic Stress Disorder in the Year 2000: Version 1 Estimates. GBD 2000 Working Paper
- Flaxman, 2013, An Integrative Metaregression Framework for Descriptive Epidemiology
- 1997, National Survey of Mental Health and Wellbeing, 1997 (SMHWB)
- 2001–2002, National Epidemiologic Survey on Alcohol and Related Conditions Wave 1 and Wave 2
- 2008, The Global Burden of Disease: 2004 Update
- 2009, United States Medical Expenditure Panel Survey (MEPS) 2000–2009
- 2013, Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5)
- 2000, Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision (DSM-IV-TR)
- Andrews, 2007, Tolkien II: A Needs-based, Costed Stepped-care Model for Mental Health Services
- 1993, The ICD-10 Classification of Mental and Behavioural Disorders: Diagnostic Criteria for Research
Cited by
Sorted by citations
Items 701–767 of 767
Linking the Biological Marker Goal-Conflict Specific Rhythmicity (GCSR) and Anxiety Disorder
McNaughton, N., & Glue, P. (2024) · Springer eBooks · doi:10.1007/978-3-031-32035-4_17-1
Perceptions and Use of Extended‐Duration Exposure Therapy Amongst Psychologists
Caton, R., & Graham, B. M. (2025) · Journal of Clinical Psychology · doi:10.1002/jclp.23767
Grundlagen der Diagnostik und Therapie
(2024) · Elsevier eBooks · doi:10.1016/b978-3-437-22487-4.16001-0
Virtual Reality Applications for Social Anxiety Treatment: A Comprehensive Literature Review
Agarwal, P., Arya, P. K., Gupta, B., Shrivastava, P., Tuli, K., & Hussain, S. (2024) · International Conference on Computational Intelligence and Network Systems (CINS) · doi:10.1109/cins63881.2024.10864445
Sleep disturbance in panic disorder
Yakovleva, E. V., & Korabelnikova, E. A. (2025) · Meditsinskiy sovet = Medical Council · doi:10.21518/ms2025-080
Sun, X., Zhang, L., Pan, Y., Ni, K., Ji, C., Zhou, Q., Stuart, S. P., & Luo, Y. (2025) · Clinics · doi:10.1016/j.clinsp.2025.100664 · Cited by 1
Dell’Osso, L., Amatori, G., Nardi, B., Bonelli, C., Massimetti, E., Cremone, I. M., & Carpita, B. (2024) · Clinical Practice and Epidemiology in Mental Health · doi:10.2174/0117450179311749241009071721
Sleep’s Role for Enhancing Extinction Memory in Anxiety Disorders: Implications for Exposure Therapy
Cox, R. C., Bottary, R. M., Alfano, C. A., & Pace-Schott, E. F. (2025) · Current Sleep Medicine Reports · doi:10.1007/s40675-025-00331-1
“Anxiety disorders are common globally [1] and pose a significant public health burden [2].”
Sindhumathi, R., Tamilselvi, S., & Jeyagowri, M. (2025) · Journal of Pharmacy And Bioallied Sciences · doi:10.4103/jpbs.jpbs_1763_24
Anxiety, depression and suicide risk in students for competitive examinations
Santos, C. P. (2023) · Contemporary Readings in Law and Social Justice · doi:10.52783/crlsj.482
Olivar, N., Carbonetti, F. L., Brusco, L. I., & Priebe, S. (2025) · PLoS ONE · doi:10.1371/journal.pone.0321744
“Systematic reviews estimate the global point prevalence rate of anxiety disorders at 7.3% [1], and identify these disorders as the sixth leading cause of disability [2], in terms of years of life with disability.”
InfluentialHealth-related quality of life of small-scale farmers in southeastern Nigeria
Nwankwo, C. U., Aluh, D. O., Ikehi, M. E., Ifeanyieze, F. O., & Omeje, B. A. (2025) · Cogent Social Sciences · doi:10.1080/23311886.2025.2516884 · Cited by 1
“…2019; ikejiofor & ali, 2014; Su et al., 2021). anxiety and depression are among the commonest psychological disorders globally (aluh et al., 2019; Baxter et al., 2014; James et al., 2007). in this study, it may be associated with uncertainties of the occupation, especially with issues related to…”
A Study of Gender Differences in Cognitive Functions of Patients Suffering with Anxiety Disorders
Kachhadia, M. P., Ghildiyal, R., Acharya, A., & Gupta, A. (2025) · Annals of Indian Psychiatry · doi:10.4103/aip.aip_108_25
齐, 晗. (2025) · Journal of Clinical Personalized Medicine · doi:10.12677/jcpm.2025.44435
Olaleye, A. O., Kabir, E., & Khanam, R. (2025) · JMIR Mental Health · doi:10.2196/77652
Linking the Biological Marker Goal-Conflict Specific Rhythmicity (GCSR) and Anxiety Disorder
McNaughton, N., & Glue, P. (2025) · Springer eBooks · doi:10.1007/978-3-031-73368-0_17
Renner, V., Duhm, J., Lorenz, T., Joraschky, P., & Petrowski, K. (2025) · Journal of Clinical Psychology · doi:10.1002/jclp.70055 · Cited by 1
Research on the Psychological Health Needs of Urban Solitary Youth in the Context of Smart Home
王, 胜. (2024) · Advances in Psychology · doi:10.12677/ap.2024.1412931
Lauridsen, S., Nielsen, M. B. D., Kusier, A. O., Cloos, C. Ø., Jensen, M. P., Andersen, S., Thygesen, L. C., & Folker, A. P. (2022) · Figshare · doi:10.6084/m9.figshare.19373451
Czamara, D., Neufang, A., Dieterle, R., Iurato, S., Arloth, J., Martins, J., Ising, M., Binder, E. E., & Erhardt, A. (2022) · Figshare · doi:10.6084/m9.figshare.19670068
Czamara, D., Neufang, A., Dieterle, R., Iurato, S., Arloth, J., Martins, J., Ising, M., Binder, E. E., & Erhardt, A. (2022) · Figshare · doi:10.6084/m9.figshare.19670095
Czamara, D., Neufang, A., Dieterle, R., Iurato, S., Arloth, J., Martins, J., Ising, M., Binder, E. E., & Erhardt, A. (2022) · Figshare · doi:10.6084/m9.figshare.19670077
Sandin, K., Gjengedal, R. G. H., Osnes, K., Hannisdal, M., Berge, T., Leversen, J. S. R., Røv, L. G., Reme, S. E., Lagerveld, S. E., Blonk, R. W. B., et al. (2021) · Figshare · doi:10.6084/m9.figshare.17087893
Czamara, D., Neufang, A., Dieterle, R., Iurato, S., Arloth, J., Martins, J., Ising, M., Binder, E. E., & Erhardt, A. (2022) · Figshare · doi:10.6084/m9.figshare.19670080
Czamara, D., Neufang, A., Dieterle, R., Iurato, S., Arloth, J., Martins, J., Ising, M., Binder, E. E., & Erhardt, A. (2022) · Figshare · doi:10.6084/m9.figshare.19670074
Kolaas, K., Berman, A. H., Hedman-Lagerlöf, E., Zakrevska, A., Epstein, M., Hammarberg, S. A. W., & Axelsson, E. (2023) · Figshare · doi:10.6084/m9.figshare.22608572
Czamara, D., Neufang, A., Dieterle, R., Iurato, S., Arloth, J., Martins, J., Ising, M., Binder, E. E., & Erhardt, A. (2022) · Figshare · doi:10.6084/m9.figshare.19670089
Kolaas, K., Berman, A. H., Hedman-Lagerlöf, E., Zakrevska, A., Epstein, M., Hammarberg, S. A. W., & Axelsson, E. (2023) · Figshare · doi:10.6084/m9.figshare.22608566
Czamara, D., Neufang, A., Dieterle, R., Iurato, S., Arloth, J., Martins, J., Ising, M., Binder, E. E., & Erhardt, A. (2022) · Figshare · doi:10.6084/m9.figshare.19670062
Czamara, D., Neufang, A., Dieterle, R., Iurato, S., Arloth, J., Martins, J., Ising, M., Binder, E. E., & Erhardt, A. (2022) · Figshare · doi:10.6084/m9.figshare.19670083
Czamara, D., Neufang, A., Dieterle, R., Iurato, S., Arloth, J., Martins, J., Ising, M., Binder, E. E., & Erhardt, A. (2022) · Figshare · doi:10.6084/m9.figshare.19670065
Czamara, D., Neufang, A., Dieterle, R., Iurato, S., Arloth, J., Martins, J., Ising, M., Binder, E. E., & Erhardt, A. (2022) · Figshare · doi:10.6084/m9.figshare.19670059
Parker, E. L., Banfield, M., Fassnacht, D. B., Hatfield, T., & Kyrios, M. (2021) · Figshare · doi:10.6084/m9.figshare.14601884
Mehrabi, F., Amiri, P., Cheraghi, L., Kheradmand, A., Hosseinpanah, F., & Azizi, F. (2021) · Figshare · doi:10.6084/m9.figshare.14168134
Jia, Y., Cheng, S., Liu, L., Cheng, B., Liang, C., Ye, J., Chu, X., Yao, Y., Wen, Y., Kafle, O. P., et al. (2023) · Figshare · doi:10.6084/m9.figshare.22621126
Czamara, D., Neufang, A., Dieterle, R., Iurato, S., Arloth, J., Martins, J., Ising, M., Binder, E. E., & Erhardt, A. (2022) · Figshare · doi:10.6084/m9.figshare.19670056
Czamara, D., Neufang, A., Dieterle, R., Iurato, S., Arloth, J., Martins, J., Ising, M., Binder, E. E., & Erhardt, A. (2022) · Figshare · doi:10.6084/m9.figshare.19670086
Czamara, D., Neufang, A., Dieterle, R., Iurato, S., Arloth, J., Martins, J., Ising, M., Binder, E. E., & Erhardt, A. (2022) · Figshare · doi:10.6084/m9.figshare.19670092
Czamara, D., Neufang, A., Dieterle, R., Iurato, S., Arloth, J., Martins, J., Ising, M., Binder, E. E., & Erhardt, A. (2022) · Figshare · doi:10.6084/m9.figshare.19670053
Czamara, D., Neufang, A., Dieterle, R., Iurato, S., Arloth, J., Martins, J., Ising, M., Binder, E. E., & Erhardt, A. (2022) · Figshare · doi:10.6084/m9.figshare.19670044
Bögemann, S. A., Riepenhausen, A., Puhlmann, L. M. C., Bar, S., Hermsen, E. J. C., Mituniewicz, J., Reppmann, Z. C., Uściƚko, A., van Leeuwen, J. M. C., Wackerhagen, C., et al. (2023) · Figshare · doi:10.6084/m9.figshare.24037207
Kolaas, K., Berman, A. H., Hedman-Lagerlöf, E., Zakrevska, A., Epstein, M., Hammarberg, S. A. W., & Axelsson, E. (2023) · Figshare · doi:10.6084/m9.figshare.22608569
Czamara, D., Neufang, A., Dieterle, R., Iurato, S., Arloth, J., Martins, J., Ising, M., Binder, E. E., & Erhardt, A. (2022) · Figshare · doi:10.6084/m9.figshare.19670050
Czamara, D., Neufang, A., Dieterle, R., Iurato, S., Arloth, J., Martins, J., Ising, M., Binder, E. E., & Erhardt, A. (2022) · Figshare · doi:10.6084/m9.figshare.19670071
Long, D., Bonsel, G. J., Lubetkin, E. I., Janssen, M. F., & Haagsma, J. A. (2022) · Figshare · doi:10.6084/m9.figshare.21581963
Jia, Y., Cheng, S., Liu, L., Cheng, B., Liang, C., Ye, J., Chu, X., Yao, Y., Wen, Y., Kafle, O. P., et al. (2023) · Figshare · doi:10.6084/m9.figshare.22621132
Jia, Y., Cheng, S., Liu, L., Cheng, B., Liang, C., Ye, J., Chu, X., Yao, Y., Wen, Y., Kafle, O. P., et al. (2023) · Figshare · doi:10.6084/m9.figshare.22621129
Haghighi, Z., Rezaei, S., & Pourramzani, A. (2025) · Acta Psychologica · doi:10.1016/j.actpsy.2025.106135
Legon, J. K., Ni, Y., & Legon, W. (2026) · medRxiv · doi:10.64898/2026.01.05.26343461
Chen, D. T.-L., Yang, K.-J., Malau, I. A., Yang, Y.-C., Satyanarayanan, S. K., Liao, H.-F., Chang, H.-C., Chang, J. P., Chiu, Y., & Su, K. (2026) · Journal of Affective Disorders · doi:10.1016/j.jad.2026.121313
Ren, Y., Yan, G., Gao, J., Chu, W., Yang, X., Xie, J., Hui, P., Su, X., Ma, W., Hou, Y., et al. (2026) · Chinese Herbal Medicines · doi:10.1016/j.chmed.2026.03.005 · Cited by 2
Duffy, J., Charura, D., & Shevchenko, J. (2026) · Psychological Reports · doi:10.1177/00332941261438057
Pacella, R., Mathews, B., Lawrence, D. M., Madzoska, M., Malacova, E., Erskine, H. E., Thomas, H. J., Higgins, D. J., Haslam, D. M., Meinck, F., et al. (2026) · Epidemiology and Psychiatric Sciences · doi:10.1017/s2045796026100572
“In GBD studies, anxiety disorders are aggregated (Baxter et al. , 2014), while in ACMS, only PTSD and GAD were measured.”
Microbial-derived mediators of the gut–brain axis: Implications for neurological disorders
Abady, M. M., Shawky, A. M., & Mohammed, D. M. (2026) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2026.110394
Röttgers, H. O., Westhoff, M., & Voderholzer, U. (2026) · Verhaltenstherapie · doi:10.1159/000552290
Roberts, L., Cumming, C., Budgeon, C. A., Preen, D. B., & Lee, K. (2026) · International Journal of Clinical Pharmacy · doi:10.1007/s11096-026-02176-2
“QoL impairments associated with anxiety disorders include reduced self-esteem, poorer physical health, impaired daily functioning, and socioeconomic disadvantage [7, 10, 11, 13–17], with comorbid mental and physical health conditions often compounding these impacts [2, 15].”
Wang, Z., Cai, Y., Zhong, X., Wang, J., Lin, B., Liu, L., Li, S., Sun, J., & Zhang, Q. (2026) · Discover Mental Health · doi:10.1007/s44192-026-00509-1
“Previous analyses based on GBD data showed that anxiety disorders contributed substantially to the global burden of disease and that women generally experienced a higher burden than men [17,18].”
Okul Psikolojik Danışmanlığında Stres ve Kaygının Önlenmesine Yönelik Yaklaşımlar
Shabanı, S. M., Çelik, P., Karaman, T., & Dönmez, R. (2026) · İstanbul Eğitim Dergisi · doi:10.71270/istanbulegitim.istj.1893729
Zainal, N. H. (2024) · OSF Preprints (OSF Preprints)
Jäger, M., Goerigk, S. A., Heinig, I., Arolt, V., Bartnick, C., Dannlowski, U., Deckert, J., Domschke, K., Fydrich, T., Hamm, A. O., et al. (2026) · Psychiatry Research · doi:10.1016/j.psychres.2026.117382
Yuan, M.-L., Liang, X.-Q., Jin, W.-Y., Zheng, M., Feng, S.-Y., Zhao, J.-L., Li, S.-R., Zhu, L.-L., Tan, L., Zeng, Y.-D., et al. (2026) · Frontiers in Public Health · doi:10.3389/fpubh.2026.1916777
“8 (17).”
Speer, K. E., McKune, A. J., & Naumovski, N. (2026) · Exploratory Research and Hypothesis in Medicine · doi:10.14218/erhm.2025.00088
Zhang, Z., Wang, J., Jing, Y., Zang, W., & Pa, W. A. M. W. (2026) · Frontiers in Psychology · doi:10.3389/fpsyg.2026.1742433
Transdiagnostic physiological correlates of unpredictable threat anticipation
Carsten, H. P., Härpfer, K., Kausche, F. M., & Riesel, A. (2026) · International Journal of Clinical and Health Psychology · doi:10.1016/j.ijchp.2026.100723
“Anxiety disorders are highly prevalent (Baxter et al., 2013), debilitating, and account for a substantial share of the disease burden attributable to mental disorders, as measured by disability-adjusted life years (Baxter et al., 2014; Murray et al., 2012).”
Endhoven, B., Vlaeyen, J. W. S., Cort, K. D., Matthijssen, S. J. M. A., de Jongh, A., van Minnen, A., Duits, P., Schruers, K. R. J., & Engelhard, I. M. (2026) · Journal of Behavior Therapy and Experimental Psychiatry · doi:10.1016/j.jbtep.2026.102136
Mukai, K., Matsuura, N., Hosoi, Y., Sakurai, M., Yamanishi, K., & Matsunaga, H. (2026) · Medicina · doi:10.3390/medicina62101970
BindingDB (2021) · UC San Diego · doi:10.7270/q2251njc
Metadata
- Authors
- Baxter, A. J., Vos, T., Scott, K. M., Ferrari, A. J., & Whiteford, H. A.
- Affiliations
- The University of Queensland (AU)
- University of Washington (US)
- University of Otago (NZ)
- Corresponding author
- Baxter, A. J.
- Venue
- Psychological Medicine
- Publisher
- Cambridge University Press (CUP)
- Published
- 2014-01-22
- Volume
- 44
- Issue
- 11
- Pages
- 2363-2374
- ISSN
- 0033-2917 (ISSN-L)
- 1469-8978
- OpenAlex
- W2007965977
- Cited by
- 768
- References
- 31
- Citations by year
- 2026: 30 · 2025: 56 · 2024: 82 · 2023: 112 · 2022: 103 · 2021: 84 · 2020: 106 · 2019: 62 · 2018: 53 · 2017: 39 · 2016: 23 · 2015: 9 · 2014: 8
- FWCI
- 38.96
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Psychological Medicine (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Bill and Melinda Gates Foundation
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Mental Health Treatment and Access
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Social Sciences › Psychology › Clinical Psychology › Child and Adolescent Psychosocial and Emotional Development
- Keywords
- anxiety disorders, global burden of disease, disability-adjusted life years, years lived with disability, suicide mortality, prevalence, sex differences, age distribution, regional variation, low- and middle-income countries
- MeSH terms
- Adolescent, Adult, Aged, Aged, 80 and over, Anxiety Disorders, Female, Humans, Male, Middle Aged, Global Health, Cost of Illness, Young Adult
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review