The DOI matches its Crossref record; 220 of the 220 references it cites were found in a registry or an index.
Exposure to early adversity: Points of cross-species translation that can lead to improved understanding of depression
Open accessAbstract
The relationship between developmental exposure to adversity and affective disorders is reviewed. Adversity discussed herein includes physical and sexual abuse, neglect, or loss of a caregiver in humans. While these stressors can occur at any point during development, the unique temporal relationship to specific depressive symptoms was the focus of discussion. Further influences of stress exposure during sensitive periods can vary by gender and duration of abuse as well. Data from animal studies are presented to provide greater translational and causal understanding of how sensitive periods, different types of psychosocial stressors, and sex interact to produce depressive-like behaviors. Findings from maternal separation, isolation rearing, chronic variable stress, and peer–peer rearing paradigms clarify interpretation about how various depressive behaviors are influenced by age of exposure. Depressive behaviors are broken down into the following categories: mood and affect, anhedonia, energy, working memory, sleep–wake, appetite changes, suicide, and general malaise. Cross-species evidence from humans, nonhuman primates, rats, and mice within each of these categories is discussed. In conclusion, sensitive periods for affective-related behaviors (anxiety, mood, and controllability) occur earlier in life, while other aspects of depression are associated with adversity later during adolescence.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Our findings support the proposition from multiple domains of analysis that exposure to stress early in life had a dose-dependent effect on increasing the risk of later psychopathology, particularly in the domain of internalizing behaviours (Andersen 2015).”
From The effects of paternal depression on child and adolescent outcomes: A systematic review (2016) · cites this paper as Andersen 2015
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Felitti, V. J., Anda, R. F., Nordenberg, D., Williamson, D. F., Spitz, A. M., Edwards, V., Koss, M. P., & Marks, J. S. (1998) · American Journal of Preventive Medicine · doi:10.1016/s0749-3797(98)00017-8 · Cited by 18,943
Kessler, R. C. (1994) · Archives of General Psychiatry · doi:10.1001/archpsyc.1994.03950010008002 · Cited by 12,370
Child abuse: Adolescent records vs. adult recall
Femina, D. D., Yeager, C. A., & Lewis, D. O. (1990) · Child Abuse & Neglect · doi:10.1016/0145-2134(90)90033-p · Cited by 8,820
Liu, D., Diorio, J., Tannenbaum, B., Caldji, C., Francis, D., Freedman, A., Sharma, S., Pearson, D., Plotsky, P. M., & Meaney, M. J. (1997) · Science · doi:10.1126/science.277.5332.1659 · Cited by 3,170
The period of susceptibility to the physiological effects of unilateral eye closure in kittens
Hubel, D. H., & Wiesel, T. N. (1970) · The Journal of Physiology · doi:10.1113/jphysiol.1970.sp009022 · Cited by 3,030
Dube, S. R., Anda, R. F., Felitti, V. J., Chapman, D. P., Williamson, D. F., & Giles, W. H. (2001) · JAMA · doi:10.1001/jama.286.24.3089 · Cited by 2,296
Allostasis and Allostatic Load Implications for Neuropsychopharmacology
McEwen, B. (2000) · Neuropsychopharmacology · doi:10.1016/s0893-133x(99)00129-3 · Cited by 1,833
Neuroscience of attention-deficit/hyperactivity disorder: the search for endophenotypes
Castellanos, F. X., & Tannock, R. (2002) · Nature Reviews Neuroscience · doi:10.1038/nrn896 · Cited by 1,827 · cited 1×
“Given that animals will never sufficiently model the human condition and its complexities (Andersen & Thompson, 2011), the more appropriate terminology that should be used is endophenotype (e.g., Castellanos & Tannock, 2002).”
BackgroundTraumatic Events and Posttraumatic Stress in Childhood
Copeland, W., Keeler, G. P., Angold, A. C., & Costello, E. J. (2007) · Archives of General Psychiatry · doi:10.1001/archpsyc.64.5.577 · Cited by 1,643
Plotsky, P. M., & Meaney, M. J. (1993) · Molecular Brain Research · doi:10.1016/0169-328x(93)90189-v · Cited by 1,638 · cited 2×
“Changes in growth and eating behavior are programmed early in life (Kuhn, Pauk, & Schanberg, 1990; Plotsky & Meaney, 1993).”
BackgroundMethod
Research works printed but not linked: 3
- Wolk, 1995, American Psychiatric Press review of psychiatry, 14227
- Pollack, 1998, New psychotherapy for men, 147
- 10.2466/pr0.1973.32.3.1011 · DOI
Cited by
Sorted by citations
Early life stress and development: potential mechanisms for adverse outcomes
Smith, K. E., & Pollak, S. D. (2020) · Journal of Neurodevelopmental Disorders · doi:10.1186/s11689-020-09337-y · Cited by 500
Animal models of major depression: drawbacks and challenges
Planchez, B., Surget, A., & Belzung, C. (2019) · Journal of Neural Transmission · doi:10.1007/s00702-019-02084-y · Cited by 480
Sensitive periods of substance abuse: Early risk for the transition to dependence
Jordan, C. J., & Andersen, S. L. (2017) · Developmental Cognitive Neuroscience · doi:10.1016/j.dcn.2016.10.004 · Cited by 455
“The long-term impact of stress during development may be diferent from that of stress in adults (Andersen, 2015; Fareri and ottenham, 2016).”
Self-citationSmith, K. E., & Pollak, S. D. (2020) · Perspectives on Psychological Science · doi:10.1177/1745691620920725 · Cited by 379
Tractenberg, S. G., Levandowski, M. L., de Azeredo, L. A., Orso, R., Roithmann, L. G., Hoffmann, E. S., Brenhouse, H., & Grassi-Oliveira, R. (2016) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2016.06.021 · Cited by 267
The effects of paternal depression on child and adolescent outcomes: A systematic review
Sweeney, S., & MacBeth, A. (2016) · Journal of Affective Disorders · doi:10.1016/j.jad.2016.05.073 · Cited by 257
Amygdala Circuit Substrates for Stress Adaptation and Adversity
Zhang, W.-H., Zhang, J.-Y., Holmes, A., & Pan, B.-X. (2021) · Biological Psychiatry · doi:10.1016/j.biopsych.2020.12.026 · Cited by 196
The stressed brain of humans and rodents
Joëls, M., Karst, H., & Sarabdjitsingh, R. A. (2018) · Acta Physiologica · doi:10.1111/apha.13066 · Cited by 210
The epigenetic impacts of social stress: how does social adversity become biologically embedded?
Cunliffe, V. T. (2016) · Epigenomics · doi:10.2217/epi-2016-0075 · Cited by 141
Depression subtyping based on evolutionary psychiatry: Proximate mechanisms and ultimate functions
Rantala, M. J., Luoto, S., Krams, I. A., & Karlsson, H. (2017) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2017.10.012 · Cited by 125
How Early Life Stress Impact Maternal Care: A Systematic Review of Rodent Studies
Orso, R., Creutzberg, K. C., Wearick‐Silva, L. E., Viola, T. W., Tractenberg, S. G., Benetti, F., & Grassi‐Oliveira, R. (2019) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2019.00197 · Cited by 131
Bayesian Models of Development
Stamps, J. A., & Frankenhuis, W. E. (2016) · Trends in Ecology & Evolution · doi:10.1016/j.tree.2016.01.012 · Cited by 114
Kaiser, R. H., Clegg, R. A., Goer, F., Pechtel, P., Beltzer, M., Vitaliano, G. D., Olson, D. P., Teicher, M. H., & Pizzagalli, D. A. (2017) · Psychological Medicine · doi:10.1017/s0033291717002628 · Cited by 122
Environmental programming of susceptibility and resilience to stress in adulthood in male mice
Peña, C. J., Nestler, E. J., & Bagot, R. C. (2019) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2019.00040 · Cited by 97
Early-life stress and inflammation: A systematic review of a key experimental approach in rodents
Dutcher, E. G., Pama, E. A. C., Lynall, M.-E., Khan, S. A., Clatworthy, M. R., Robbins, T. W., Bullmore, E. T., & Dalley, J. W. (2020) · Brain and Neuroscience Advances · doi:10.1177/2398212820978049 · Cited by 102
Stress, sensitive periods, and substance abuse
Andersen, S. L. (2019) · Neurobiology of Stress · doi:10.1016/j.ynstr.2018.100140 · Cited by 92
Self-citationReincke, S. A. J., & Hanganu‐Opatz, I. L. (2017) · Scientific Reports · doi:10.1038/srep42042 · Cited by 81
Social isolation in rats: effects on animal welfare and molecular markers for neuroplasticity
Begni, V., Sanson, A., Pfeiffer, N., Brandwein, C., Inta, D., Talbot, S. R., Riva, M. A., Gass, P., & Mallien, A. S. (2020) · PLOS ONE · doi:10.1371/journal.pone.0240439 · Cited by 78
Dai, W., Feng, K., Sun, X., Xu, L., Wu, S., Rahman, K., Jia, D. T., & Han, T. (2021) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2021.114692 · Cited by 81
Seeding Stress Resilience through Inoculation
Ashokan, A., Sivasubramanian, M., & Mitra, R. (2016) · Neural Plasticity · doi:10.1155/2016/4928081 · Cited by 71
Encore: Behavioural animal models of stress, depression and mood disorders
Petković, A., & Chaudhury, D. (2022) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2022.931964 · Cited by 74
Neuroinflammation, Early-Life Adversity, and Brain Development
Andersen, S. L. (2022) · Harvard Review of Psychiatry · doi:10.1097/hrp.0000000000000325 · Cited by 73
Self-citationTranslational studies identify long-term impact of prior neonatal pain experience
Walker, S. M. (2017) · Pain · doi:10.1097/j.pain.0000000000000784 · Cited by 67
Andersen, S. L. (2016) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2016.07.012 · Cited by 73
Self-citationThe evolving neurobiology of early-life stress
Birnie, M. T., & Baram, T. Z. (2025) · Neuron · doi:10.1016/j.neuron.2025.02.016 · Cited by 76
Age-dependent changes in behavioural plasticity: insights from Bayesian models of development
Stamps, J. A., & Krishnan, V. V. (2017) · Animal Behaviour · doi:10.1016/j.anbehav.2017.01.013 · Cited by 63
Hill, M. N., Eiland, L. R., Lee, T. T.-Y., Hillard, C. J., & McEwen, B. S. (2018) · Neuropharmacology · doi:10.1016/j.neuropharm.2018.11.036 · Cited by 65
Nelson, L. H., Saulsbery, A. I., & Lenz, K. M. (2018) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2018.09.002 · Cited by 62
Levis, S. C., Baram, T. Z., & Mahler, S. V. (2021) · European Journal of Neuroscience · doi:10.1111/ejn.15223 · Cited by 63
Sex-specific effects of stress on metabolic and cardiovascular disease: are women at higher risk?
Murphy, M. O., & Loria, A. S. (2017) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00185.2016 · Cited by 57
Orso, R., Wearick‐Silva, L. E., Creutzberg, K. C., Centeno‐Silva, A., Roithmann, L. G., Pazzin, R., Tractenberg, S. G., Benetti, F., & Grassi‐Oliveira, R. (2017) · Stress · doi:10.1080/10253890.2017.1389883 · Cited by 58
Wei, R., Zhang, Y., Feng, Y.-Z., Zhang, K.-X., Zhang, J., Chen, J., Luo, B., Li, X., & Chen, G.-H. (2023) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2023.1172091 · Cited by 49
Adverse Childhood Experiences, Brain Development, and Mental Health: A Call for Neurocounseling
Navalta, C. P., McGee, L., & Underwood, J. (2018) · Journal of Mental Health Counseling · doi:10.17744/mehc.40.3.07 · Cited by 54
Zhou, L., Wu, Z., Wang, G., Xiao, L., Wang, H., Sun, L., & Xie, Y. (2020) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2020.172953 · Cited by 46
Adverse effects of early-life stress: focus on the rodent neuroendocrine system
Lee, S. H., & Jung, E. (2023) · Neural Regeneration Research · doi:10.4103/1673-5374.377587 · Cited by 46
How Early Life Adversity Influences Defensive Circuitry
Murthy, S. S., & Gould, E. (2020) · Trends in Neurosciences · doi:10.1016/j.tins.2020.02.001 · Cited by 42
Exposure to a maternal cafeteria diet changes open‐field behaviour in the developing offspring
Speight, A., Davey, W. G., McKenna, E., & Voigt, J. W. (2016) · International Journal of Developmental Neuroscience · doi:10.1016/j.ijdevneu.2016.12.005 · Cited by 36
Willis, E., & Dinehart, L. H. B. (2013) · Early Child Development and Care · doi:10.1080/03004430.2013.804069 · Cited by 44
Ferber, S. G., Trezza, V., & Weller, A. (2019) · Developmental Psychobiology · doi:10.1002/dev.21944 · Cited by 38
Uliana, D. L., Zhu, X., Gomes, F. V., & Grace, A. A. (2022) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2022.935320 · Cited by 36
Zhang, B. (2017) · PubMed Central · doi:10.13918/j.issn.2095-8137.2017.002 · Cited by 32
Reconsidering depression as a risk factor for substance use disorder: Insights from rodent models
Rappeneau, V., & Bérod, A. (2017) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2017.04.001 · Cited by 33
Freund, N., Thompson, B. S., Sonntag, K., Meda, S., & Andersen, S. L. (2016) · Psychopharmacology · doi:10.1007/s00213-015-4200-y · Cited by 31
Self-citationCaravaca, F., Fearn, N. E., Vidovic, K. R., & Vaughn, M. G. (2019) · Health & Social Work · doi:10.1093/hsw/hlz013 · Cited by 31
Wu, Z., Zhou, L., Sun, L., Xie, Y., Xiao, L., Wang, H., & Wang, G. (2021) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2021.03.016 · Cited by 32
Speranza, L., Filiz, K. D., Lippiello, P., Ferraro, M. G., Pascarella, S., Miniaci, M. C., & Volpicelli, F. (2024) · Biomedicines · doi:10.3390/biomedicines12091978 · Cited by 38
Endo, N., Makinodan, M., Mannari‐Sasagawa, T., Horii‐Hayashi, N., Somayama, N., Komori, T., Kishimoto, T., & Nishi, M. (2021) · Scientific Reports · doi:10.1038/s41598-020-80206-3 · Cited by 30
The Developmental Origins of Opioid Use Disorder and Its Comorbidities
Levis, S. C., Mahler, S. V., & Baram, T. Z. (2021) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2021.601905 · Cited by 33
Zhang, X., Li, H., Sun, H., Jiang, Y., Wang, A., Kong, Y., Sun, X., Zhu, G., Li, Q., Du, Z., et al. (2020) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2020.00709 · Cited by 27
Knop, J., Joëls, M., & van der Veen, R. (2017) · Current Opinion in Psychology · doi:10.1016/j.copsyc.2017.02.030 · Cited by 26
Gains and Losses: Resilience to Social Defeat Stress in Adolescent Female Mice
Pantoja-Urbán, A. H., Richer, S., Mittermaier, A., Giroux, M., Nouel, D., Hernández, G., & Flores, C. (2023) · Biological Psychiatry · doi:10.1016/j.biopsych.2023.06.014 · Cited by 29
Photoperiod during maternal pregnancy and lifetime depression in offspring
Devore, E. E., Chang, S., Okereke, O. I., McMahon, D. G., & Schernhammer, E. S. (2018) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2018.08.004 · Cited by 25
Sun, X., Zhang, Y., Li, X., Liu, X., & Qin, C. (2021) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2020.572224 · Cited by 24
Kwan, L. Y., Eaton, D. L., Andersen, S. L., Dow-Edwards, D. L., Levin, E. D., Talpos, J. C., Vorhees, C. V., & Li, A. A. (2020) · Neurotoxicology and Teratology · doi:10.1016/j.ntt.2020.106916 · Cited by 25
Self-citationGiannoni‐Guzmán, M. A., Kamitakahara, A. K., Magalong, V. M., Levitt, P. R., & McMahon, D. G. (2020) · Journal of Pineal Research · doi:10.1111/jpi.12705 · Cited by 22
Siemann, J. K., Williams, P., Malik, T. N., Jackson, C. R., Green, N. H., Emeson, R. B., Levitt, P. R., & McMahon, D. G. (2020) · Scientific Reports · doi:10.1038/s41598-020-72263-5 · Cited by 21
Segni, M. D., Andolina, D., D’Addario, S. L., Babicola, L., Ielpo, D., Luchetti, A., Pascucci, T., Iacono, L. L., D'Amato, F. R., & Ventura, R. (2019) · Neuroscience · doi:10.1016/j.neuroscience.2019.06.016 · Cited by 21
Li, M., Cui, J., Xu, B., Wei, Y., Fu, C., Lv, X., Xiong, L., & Qin, D. (2022) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2021.827541 · Cited by 23
Kim, H.-B., Yoo, J.-Y., Yoo, S.-Y., Suh, S. W., Lee, S., Park, J. H., Lee, J. H., Baik, T., Kim, H.-S., & Woo, R. (2020) · Cell Death Discovery · doi:10.1038/s41420-020-00308-9 · Cited by 19
Demers, L. A., Handley, E., Hunt, R. H., Rogosch, F., Toth, S., Thomas, K., & Cicchetti, D. (2019) · Child Maltreatment · doi:10.1177/1077559519847770 · Cited by 15
Guirado, R., Pérez-Rando, M., Ferragud, A., Gutiérrez‐Castellanos, N., Umemori, J., Carceller, H., Nácher, J., & Castillo-Gómez, E. (2020) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2020.00051 · Cited by 18
Talani, G., Biggio, F., Gorule, A. A., Licheri, V., Saolini, E., Colombo, D., Sarigu, G., Petrella, M., Vedele, F., Biggio, G., et al. (2022) · Neuropharmacology · doi:10.1016/j.neuropharm.2022.109301 · Cited by 19
Réus, G. Z., Abitante, M. S., Manosso, L. M., de Moura, A. B., Borba, L. A., Botelho, M. E. M., Darabas, A. C., Demo, J. P., Behenck, J. P., Arent, C. O., et al. (2021) · Molecular Neurobiology · doi:10.1007/s12035-021-02588-3 · Cited by 16
Siemann, J. K., Grueter, B. A., & McMahon, D. G. (2020) · Neuroscience · doi:10.1016/j.neuroscience.2020.12.010 · Cited by 17
Sexual dimorphism in pre-clinical studies of depression
Alshammari, T. K. (2020) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2020.110120 · Cited by 16
D’Addario, S. L., Segni, M. D., Ledonne, A., Piscitelli, R. M., Babicola, L., Martini, A., Spoleti, E., Mancini, C., Ielpo, D., D'Amato, F. R., et al. (2021) · Neurobiology of Stress · doi:10.1016/j.ynstr.2021.100324 · Cited by 16
Bian, Y., Ma, Y., Ma, Q., Yang, L., Zhu, Q., Li, W., & Meng, L. (2021) · BioMed Research International · doi:10.1155/2021/6681397 · Cited by 14
Siemann, J. K., Green, N. H., Reddy, N., & McMahon, D. G. (2019) · Frontiers in Neuroscience · doi:10.3389/fnins.2019.00459 · Cited by 13
Early life stress induces visual dysfunction and retinal structural alterations in adult mice
Calanni, J. S., Diéguez, H. H., Fleitas, M. F. G., Cánepa, E. T., Berardino, B. G., Repetto, E. M., Villarreal, A., Dorfman, D., & Rosenstein, R. E. (2022) · Journal of Neurochemistry · doi:10.1111/jnc.15752 · Cited by 13
Lukkes, J. L., Meda, S., Norman, K. J., & Andersen, S. L. (2018) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2018.02.005 · Cited by 12
Self-citationCeschim, V. C., Sumarán, P., Borges, A. A., Girardi, C. E. N., & Suchecki, D. (2021) · Hormones and Behavior · doi:10.1016/j.yhbeh.2021.104928 · Cited by 12
Maternal behavior promotes resilience to adolescent stress in mice through a microglia-neuron axis
Chen, H., Xu, R., Wang, J., Gao, F., Lv, Y., Li, X., Fang, L., Zhao, J., Zhang, X., Wang, J., et al. (2025) · Nature Communications · doi:10.1038/s41467-025-57810-w · Cited by 12
Neville, V., Andrews, C. P., Nettle, D., & Melissa Bateson, B. (2017) · Scientific Reports · doi:10.1038/s41598-017-13776-4 · Cited by 10
Pollano, A., Trujillo, V., & Suárez, M. M. (2017) · Stress · doi:10.1080/10253890.2017.1401062 · Cited by 8
Bupropion induces social anxiety in adolescent mice: Influence of housing conditions
Gómez, C., Redolat, R., & Carrasco, C. (2017) · Pharmacological Reports · doi:10.1016/j.pharep.2017.03.010 · Cited by 6
Macrı̀, S. (2016) · Neurobiology of Stress · doi:10.1016/j.ynstr.2016.12.001 · Cited by 7
Zahra, A., Du, L., Jia, M., Butt, M. U., Wang, Q., Wang, Y., & Wu, J. (2022) · Journal of Integrative Neuroscience · doi:10.31083/j.jin2102061 · Cited by 7
Boulanger-Bertolus, J., White, A. M., & Dębiec, J. (2017) · Current Behavioral Neuroscience Reports · doi:10.1007/s40473-017-0112-y · Cited by 7
The Cognitive–Affective Social Processing and Emotion Regulation (CASPER) model
Camacho, M. C., Deshpande, E., & Perino, M. T. (2025) · Neuropsychopharmacology · doi:10.1038/s41386-025-02224-x · Cited by 8
Mancini, C., Babicola, L., Chila, G., Segni, M. D., Municchi, D., D’Addario, S. L., Spoleti, E., Passeri, A., Cifani, C., Andolina, D., et al. (2024) · iScience · doi:10.1016/j.isci.2024.111328 · Cited by 8
Minnes, G. L., Wiener, A. J., Pisahl, A. S., Duecker, E. A., Baskhairoun, B. A., Lowe, S. C., & Simon, N. W. (2024) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2024.108016 · Cited by 6
Francis, A., McKibben, L. A., & Dwivedi, Y. (2025) · Biological Psychiatry Global Open Science · doi:10.1016/j.bpsgos.2025.100487 · Cited by 6
Parent, C. I., Nguyen, H., Wen, X., Diorio, J. C., Meaney, M. J., & Zhang, T. (2017) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2017.05.007 · Cited by 8
Early-Life Stress Drives the Molecular Mechanisms Shaping the Adult Phenotype
Huber, S., Costantini, D., Houdelier, C., & Marasco, V. (2022) · Fascinating life sciences · doi:10.1007/978-3-030-90131-8_4 · Cited by 5
The Rat in Neuroscience Research
El-Ayache, N. C., & Galligan, J. J. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-814338-4.00028-3 · Cited by 4
Alqudah, A. M., Qnais, E. Y., Gammoh, O., Bseiso, Y., Wedyan, M. A., Alqudah, M., Oqal, M. K., Abudalo, R. A., & Hatahet, T. (2024) · Psychopharmacology · doi:10.1007/s00213-024-06639-0 · Cited by 4
Arenas, M. C., Castro‐Zavala, A., Martín‐Sánchez, A., Blanco-Gandía, M. C., Miñarro, J., Valverde, O., & Manzanedo, C. (2021) · Behavioural Brain Research · doi:10.1016/j.bbr.2021.113545 · Cited by 4
Qnais, E. Y., Gammoh, O., Alqudah, M. A. Y., Al-Bzour, M. H., Wedyan, M. A., Alqudah, A. M., Alnakhli, A. M., Shilbayeh, S. A. R., Aljabali, A. A. A., & Hatahet, T. (2025) · Molecular Neurobiology · doi:10.1007/s12035-025-05483-3 · Cited by 3
Les stress pendant les 1 000 premiers jours de la vie quand tout commence
Verney, C., & Vitalis, T. (2023) · médecine/sciences · doi:10.1051/medsci/2023124 · Cited by 3
Etiopathogenesis of depression and experimental depression models used in preclinical studies
Kandemir, Ü. (2023) · European Journal of Life Sciences · doi:10.55971/ejls.1327521 · Cited by 2
Maternal separation alters peripheral immune responses associated with IFN-γ and OT in mice
Zhang, Y., Chen, H., Cao, J., Gao, L., & Yu, J. (2024) · Peptides · doi:10.1016/j.peptides.2024.171318 · Cited by 3
Proposition of a Simplified Protocol and New Parameter Introduction in NMRI Mice Anhedonia Induction
Fedrigolli, E., Bogdan, D., Lalošević, D., & Banović, P. (2021) · EABR. Experimental and Applied Biomedical Research · doi:10.2478/sjecr-2020-0021 · Cited by 2
Kim, M., Netser, S., Wagner, S., & Harony‐Nicolas, H. (2025) · Scientific Reports · doi:10.1038/s41598-025-95920-z · Cited by 2
Sigunov, A., Peciña, M., Palmatier, M. I., Sellers, E. W., Clements, A. D., & Deehan, G. A. (2025) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2025.106527 · Cited by 1
Sun, X., Qin, X., Shi, P., & Dai, Q. (2026) · BMC Public Health · doi:10.1186/s12889-025-25953-6 · Cited by 2
Repeated unpredictable stress blunts alcohol-induced memory deficit in adolescent rat
Sircar, R. (2020) · Neuroreport · doi:10.1097/wnr.0000000000001519 · Cited by 1
Rokach, A., & Clayton, S. (2023) · Elsevier eBooks · doi:10.1016/b978-0-323-85853-3.00019-7 · Cited by 2
Gasalla, P., Thomas, K. L., Wilkinson, L. S., Hall, J., & Dwyer, D. M. (2025) · Genes Brain & Behavior · doi:10.1111/gbb.70021 · Cited by 1
The Biology of Glucocorticoids: Normal and Abnormal Aggression
Haller, J. (2020) · Springer eBooks · doi:10.1007/978-3-030-46331-1_5 · Cited by 1
Hadera, V., Bobotis, B. C., Landwehr, A., Guimarães, F. S., Tremblay, M., & Gomes, F. V. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.09.03.674067 · Cited by 2
Metadata
- Authors
- Andersen, S. L.
- Affiliations
- Harvard University (US)
- Corresponding author
- Andersen, Susan L.
- ORCID
- Andersen, Susan L.
- Venue
- Development and Psychopathology
- Publisher
- Cambridge University Press (CUP)
- Published
- 2015-05
- Volume
- 27
- Issue
- 2
- Pages
- 477-491
- ISSN
- 0954-5794 (ISSN-L)
- 1469-2198
- PMC
- PMC5237807
- OpenAlex
- W2271686560
- Cited by
- 116
- References
- 217
- Citations by year
- 2026: 2 · 2025: 10 · 2024: 6 · 2023: 10 · 2022: 10 · 2021: 14 · 2020: 17 · 2019: 10 · 2018: 7 · 2017: 17 · 2016: 12
- FWCI
- 0.97
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Development and Psychopathology (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institute of Mental Health (R01MH091114)
- National Institute on Drug Abuse (R01 DA-026485-04, R01DA026485, R01DA015403, R01 DA-015403-10)
- Topics
- Life Sciences › Neuroscience › Behavioral Neuroscience › Stress Responses and Cortisol
- Social Sciences › Psychology › Clinical Psychology › Child Abuse and Trauma
- Social Sciences › Psychology › Clinical Psychology › Child and Adolescent Psychosocial and Emotional Development
- Keywords
- childhood adversity, developmental stress, depression, sensitive period, cross-species translation, psychosocial stressors, maternal separation, isolation rearing, chronic variable stress, peer rearing, sex differences, anhedonia, appetite changes, suicide, working memory, mood disorders, abuse and neglect, caregiver loss
- MeSH terms
- Animals, Anxiety, Depression, Depressive Disorder, Disease Models, Animal, Female, Humans, Male, Maternal Deprivation, Mice, Rats
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review