New Developments in Liposomal Drug Delivery

A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs.

Matsumura, Y., & Maeda, H. (1986) · PubMed · Cited by 6,781

Recent advances with liposomes as pharmaceutical carriers

Torchilin, V. P. (2005) · Nature Reviews Drug Discovery · doi:10.1038/nrd1632 · Cited by 5,282

Doxil® — The first FDA-approved nano-drug: Lessons learned

Barenholz, Y. (. (2012) · Journal of Controlled Release · doi:10.1016/j.jconrel.2012.03.020 · Cited by 4,792

Diffusion of univalent ions across the lamellae of swollen phospholipids

Bangham, A. D., Standish, M. M., & Watkins, J. C. (1965) · Journal of Molecular Biology · doi:10.1016/s0022-2836(65)80093-6 · Cited by 4,664

Cancer nanotechnology: opportunities and challenges

Ferrari, M. (2005) · Nature Reviews Cancer · doi:10.1038/nrc1566 · Cited by 4,558

The EPR effect: Unique features of tumor blood vessels for drug delivery, factors involved, and limitations and augmentation of the effect

Fang, J. Q., Nakamura, H., & Maeda, H. (2010) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2010.04.009 · Cited by 3,573

Regulation of transport pathways in tumor vessels: Role of tumor type and microenvironment

Hobbs, S. K., Monsky, W. L., Yuan, F., Roberts, W. G., Griffith, L., Torchilin, V. P., & Jain, R. K. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.8.4607 · Cited by 2,438

Procedure for preparation of liposomes with large internal aqueous space and high capture by reverse-phase evaporation.

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Photodynamic Therapy of Subfoveal Choroidal Neovascularization in Age-related Macular Degeneration With Verteporfin

Treatment of Age-related Macular Degeneration With Photodynamic Therapy (TAP) Study Group (1999) · Archives of Ophthalmology · doi:10.1001/archopht.117.10.1329 · Cited by 2,192

Production of large unilamellar vesicles by a rapid extrusion procedure. Characterization of size distribution, trapped volume and ability to maintain a membrane potential

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Tumor delivery of macromolecular drugs based on the EPR effect

Torchilin, V. P. (2010) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2010.03.011 · Cited by 2,032

Amphipathic polyethyleneglycols effectively prolong the circulation time of liposomes

Klibanov, A. L., Maruyama, K., Torchilin, V. P., & Huang, L. (1990) · FEBS Letters · doi:10.1016/0014-5793(90)81016-h · Cited by 2,030

Hyperthermia in combined treatment of cancer

Wust, P., Hildebrandt, B., Sreenivasa, G., Rau, B., Gellermann, J., Riess, H. B., FELIX, R., & Schlag, P. (2002) · The Lancet Oncology · doi:10.1016/s1470-2045(02)00818-5 · Cited by 2,002

Critical evaluation of Nanoparticle Tracking Analysis (NTA) by NanoSight for the measurement of nanoparticles and protein aggregates

Filipe, V., Hawe, A., & Jiskoot, W. (2010) · Pharmaceutical Research · doi:10.1007/s11095-010-0073-2 · Cited by 1,885

Vascular permeability in a human tumor xenograft: molecular size dependence and cutoff size.

Yuan, F., Dellian, M., Fukumura, D., Leunig, M., Berk, D. A., Torchilin, V. P., & Jain, R. K. (1995) · PubMed · Cited by 1,706

Multifunctional, stimuli-sensitive nanoparticulate systems for drug delivery

Torchilin, V. P. (2014) · Nature Reviews Drug Discovery · doi:10.1038/nrd4333 · Cited by 1,674

Physical principles of membrane organization

Israelachvili, J. N., Marĉelja, S., & Horn, R. G. (1980) · Quarterly Reviews of Biophysics · doi:10.1017/s0033583500001645 · Cited by 1,440

Single bilayer liposomes prepared without sonication

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Thermoresponsive Polymers for Biomedical Applications

Ward, M. A., & Georgiou, T. K. (2011) · Polymers · doi:10.3390/polym3031215 · Cited by 1,165

Liposome formulations with prolonged circulation time in blood and enhanced uptake by tumors.

Gabizón, A., & Papahadjopoulos, D. (1988) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.85.18.6949 · Cited by 1,134

Antibody Targeting of Long-Circulating Lipidic Nanoparticles Does Not Increase Tumor Localization but Does Increase Internalization in Animal Models

Kirpotin, D. B., Drummond, D. C., Shao, Y., Shalaby, M. R., Hong, K., Nielsen, U. B., Marks, J. D., Benz, C. C., & Park, J. W. (2006) · Cancer Research · doi:10.1158/0008-5472.can-05-4199 · Cited by 1,129

Magnetic nanoparticles for theragnostics

Shubayev, V. I., Pisanic, T. R., & Jin, S. (2009) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2009.03.007 · Cited by 1,052

Cell-Penetrating Peptides: Design, Synthesis, and Applications

Copolovici, D. M., Langel, K., Eriste, E., & Langel, Ü. (2014) · ACS Nano · doi:10.1021/nn4057269 · Cited by 997

Trends and Developments in Liposome Drug Delivery Systems

Lian, T., & Ho, R. J. Y. (2001) · Journal of Pharmaceutical Sciences · doi:10.1002/jps.1023 · Cited by 922

Liposomal Drug Delivery Systems: An Update Review

Samad, A., Sultana, Y., & Aqil, M. (2007) · Current Drug Delivery · doi:10.2174/156720107782151269 · Cited by 909

Cell‐penetrating peptides: 20 years later, where do we stand?

Bechara, C., & Sagan, S. (2013) · FEBS Letters · doi:10.1016/j.febslet.2013.04.031 · Cited by 906

Novel applications of liposomes

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PET versus SPECT: strengths, limitations and challenges

Rahmim, A., & Zaidi, H. (2008) · Nuclear Medicine Communications · doi:10.1097/mnm.0b013e3282f3a515 · Cited by 843

Clinical development of liposome based drugs: formulation, characterization, and therapeutic efficacy

Yeh, M., Chang, H., & Cheng, M.-Y. (2011) · International Journal of Nanomedicine · doi:10.2147/ijn.s26766 · Cited by 801

The role of dioleoyl phosphatidylethanolamine in cationic liposome mediated gene transfer

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Overexpression of a novel anionic glutathione transferase in multidrug-resistant human breast cancer cells.

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A new temperature-sensitive liposome for use with mild hyperthermia: characterization and testing in a human tumor xenograft model.

Needham, D., Anyarambhatla, G., Kong, G., & Dewhirst, M. W. (2000) · PubMed · Cited by 746

Preparation, Characterization and Applications of Liposomes: State of the Art

Laouini, A., Jaafar‐Maalej, C., Limayem, I., Sfar, S., Charcosset, C., & Fessi, H. (2012) · Journal of Colloid Science and Biotechnology · doi:10.1166/jcsb.2012.1020 · Cited by 699

Nanoliposomes and Their Applications in Food Nanotechnology

Mozafari, M. R., Johnson, C. J., Hatziantoniou, S., & Demetzos, C. (2008) · Journal of Liposome Research · doi:10.1080/08982100802465941 · Cited by 687

Liposomes as immunological adjuvants

Allison, A. C., & Gregoriadis, G. C. (1974) · Nature · doi:10.1038/252252a0 · Cited by 676

Current Trends in The Use of Liposomes for Tumor Targeting

Deshpande, P. P., Biswas, S., & Torchilin, V. P. (2013) · Nanomedicine · doi:10.2217/nnm.13.118 · Cited by 663

Anti-HER2 immunoliposomes: enhanced efficacy attributable to targeted delivery.

Park, J. W., Hong, K., Kirpotin, D. B., Colbern, G. T., Shalaby, R., Baselga, J. M., Shao, Y. Y., Nielsen, U. B., Marks, J. D., Moore, D. H., et al. (2002) · PubMed · Cited by 652

Formation and properties of thin‐walled phospholipid vesicles

Reeves, J. P., & Dowben, R. M. (1969) · Journal of Cellular Physiology · doi:10.1002/jcp.1040730108 · Cited by 651

The Carrier Potential of Liposomes in Biology and Medicine

Gregoriadis, G. (1976) · New England Journal of Medicine · doi:10.1056/nejm197609232951305 · Cited by 596

Effect of the cholesterol content of small unilamellar liposomes on their stability in vivo and in vitro

Kirby, C. J., Clarke, J., & Gregoriadis, G. (1980) · Biochemical Journal · doi:10.1042/bj1860591 · Cited by 592

GALA: a designed synthetic pH-responsive amphipathic peptide with applications in drug and gene delivery

Li, W. (2004) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2003.10.041 · Cited by 588

Advanced strategies in liposomal cancer therapy: Problems and prospects of active and tumor specific drug release

Andresen, T. L., Jensen, S. S., & Jørgensen, K. (2005) · Progress in Lipid Research · doi:10.1016/j.plipres.2004.12.001 · Cited by 580

Liposomes from ionic, single-chain amphiphiles

Hargreaves, W. R., & Deamer, D. W. (1978) · Biochemistry · doi:10.1021/bi00611a014 · Cited by 576

Liposomal Nanocapsules in Food Science and Agriculture

Taylor, T. M., Weiß, J., Davidson, P. M., & Bruce, B. D. (2005) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408390591001135 · Cited by 569

Preparation and characterization of liposomes as therapeutic delivery systems: a review

Vemuri, S., & Rhodes, C. T. (1995) · Pharmaceutica Acta Helvetiae · doi:10.1016/0031-6865(95)00010-7 · Cited by 566

An overview of liposome lyophilization and its future potential

Chen, C., Han, D., Cai, C., & Tang, X. (2009) · Journal of Controlled Release · doi:10.1016/j.jconrel.2009.10.024 · Cited by 547

Osmotic properties and water permeability of phospholipid liquid crystals

Bangham, A. D., de Gier, J., & Greville, G. D. (1967) · Chemistry and Physics of Lipids · doi:10.1016/0009-3084(67)90030-8 · Cited by 546

Controlled Vesicle Self-Assembly in Microfluidic Channels with Hydrodynamic Focusing

Jahn, Α., Vreeland, W. N., Gaitan, M., & Locascio, L. E. (2004) · Journal of the American Chemical Society · doi:10.1021/ja0318030 · Cited by 539

A randomized controlled trial comparing intrathecal sustained-release cytarabine (DepoCyt) to intrathecal methotrexate in patients with neoplastic meningitis from solid tumors.

Glantz, M., Jaeckle, K. A., Chamberlain, M. C., Phuphanich, S., Recht, L. D., Swinnen, L. J., Maria, B., LaFollette, S., Schumann, G. B., Cole, B. F., et al. (1999) · PubMed · Cited by 529

Liposomes as vaccine delivery systems: a review of the recent advances

Schwendener, R. A. (2014) · Therapeutic Advances in Vaccines · doi:10.1177/2051013614541440 · Cited by 524

Liposome−Cell Interactions in Vitro: Effect of Liposome Surface Charge on the Binding and Endocytosis of Conventional and Sterically Stabilized Liposomes

Miller, C. R., Bondurant, B., McLean, S. D., McGovern, K. A., & O’Brien, D. F. (1998) · Biochemistry · doi:10.1021/bi980096y · Cited by 523

Influence of surface hydrophilicity of liposomes on their interaction with plasma protein and clearance from the circulation: Studies with poly(ethylene glycol)-coated vesicles

Senior, J. H., Delgado, C., Fisher, D., Tilcock, C., & Gregoriadis, G. (1991) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/0005-2736(91)90337-8 · Cited by 521

The effect of particle size and charge on the clearance rates of liposomes and liposome encapsulated drugs

Juliano, R. L., & Stamp, D. (1975) · Biochemical and Biophysical Research Communications · doi:10.1016/s0006-291x(75)80433-5 · Cited by 521

Oral delivery of anticancer drugs: Challenges and opportunities

Thanki, K., Gangwal, R. P., Sangamwar, A. T., & Jain, S. (2013) · Journal of Controlled Release · doi:10.1016/j.jconrel.2013.04.020 · Cited by 510

Liposome oxidation and erythrocyte lysis by enzymically generated superoxide and hydrogen peroxide.

Kellogg, E. W., & Fridovich, I. (1977) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)39909-x · Cited by 509

Liposome-based drug delivery in breast cancer treatment

Park, J. W. (2002) · Breast Cancer Research · doi:10.1186/bcr432 · Cited by 474

Marqibo® (vincristine sulfate liposome injection) improves the pharmacokinetics and pharmacodynamics of vincristine

Silverman, J. A., & Deitcher, S. R. (2012) · Cancer Chemotherapy and Pharmacology · doi:10.1007/s00280-012-2042-4 · Cited by 474

Liposomes with prolonged circulation times: factors affecting uptake by reticuloendothelial and other tissues

Allen, T. M., Hansen, C., & Rutledge, J. M. (1989) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/0005-2736(89)90078-3 · Cited by 467

The size of liposomes: a factor which affects their targeting efficiency to tumors and therapeutic activity of liposomal antitumor drugs

Nagayasu, A., Uchiyama, K., & Kiwada, H. (1999) · Advanced Drug Delivery Reviews · doi:10.1016/s0169-409x(99)00041-1 · Cited by 440

Sterically Stabilized Anti-HER2 Immunoliposomes: Design and Targeting to Human Breast Cancer Cells in Vitro

Kirpotin, D. B., Park, J. W., Hong, K., Zalipsky, S., Li, W., Carter, P. M., Benz, C. C., & Papahadjopoulos, D. (1997) · Biochemistry · doi:10.1021/bi962148u · Cited by 438

Randomized phase III trial of liposomal daunorubicin versus doxorubicin, bleomycin, and vincristine in AIDS-related Kaposi's sarcoma.

Gill, P. S., Wernz, J., Scadden, D. T., Cohen, P., Mukwaya, G., Roenn, J. H. V., Jacobs, M., Kempin, S. J., Silverberg, I. J., Gonzales, G., et al. (1996) · Journal of Clinical Oncology · doi:10.1200/jco.1996.14.8.2353 · Cited by 438

Solute distributions and trapping efficiencies observed in freeze-thawed multilamellar vesicles

Mayer, L. D., Hope, M. J., Cullis, P. R., & Janoff, A. S. (1985) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/0005-2736(85)90084-7 · Cited by 436

Microfluidic Mixing and the Formation of Nanoscale Lipid Vesicles

Jahn, Α., Stavis, S. M., Hong, J. S., Vreeland, W. N., DeVoe, D. L., & Gaitan, M. (2010) · ACS Nano · doi:10.1021/nn901676x · Cited by 434

Targeted Liposomal Drug Delivery to Monocytes and Macrophages

Kelly, C., Jefferies, C. A., & Cryan, S. (2010) · Journal of Drug Delivery · doi:10.1155/2011/727241 · Cited by 426

Cell transfection in vitro and in vivo with nontoxic TAT peptide-liposome–DNA complexes

Torchilin, V. P., Levchenko, T. S., Rammohan, R., Volodina, N., Papahadjopoulos‐Sternberg, B., & D’Souza, G. G. M. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0435906100 · Cited by 419

Thermosensitive liposomes for localized delivery and triggered release of chemotherapy

Ta, T., & Porter, T. M. (2013) · Journal of Controlled Release · doi:10.1016/j.jconrel.2013.03.036 · Cited by 418

p H-Sensitive Liposomes: Possible Clinical Implications

Yatvin, M. B., Kreutz, W., Horwitz, B. A., & Shinitzky, M. (1980) · Science · doi:10.1126/science.7434025 · Cited by 415

Triggered release from liposomes through magnetic actuation of iron oxide nanoparticle containing membranes

Amstad, E., Kohlbrecher, J., Müller, E., Schweizer, T., Textor, M., & Reimhult, E. (2011) · Nano Letters · doi:10.1021/nl2001499 · Cited by 397

Challenges in Development of Targeted Liposomal Therapeutics

Sawant, R. R., & Torchilin, V. P. (2012) · The AAPS Journal · doi:10.1208/s12248-012-9330-0 · Cited by 393

Deformable liposomes and ethosomes: Mechanism of enhanced skin delivery

Elsayed, M. M. A., Abdallah, O. Y., Naggar, V. F., & Khalafallah, N. M. (2006) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2006.05.027 · Cited by 385

Microfluidic methods for forming liposomes

van Swaay, D., & deMello, A. J. (2012) · Lab on a Chip · doi:10.1039/c2lc41121k · Cited by 382

Pharmaceutical nanotechnology for oral delivery of anticancer drugs

Mei, L., Zhang, Z., Zhao, L., Huang, L., Yang, X., Tang, J., & Feng, S. (2012) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2012.11.005 · Cited by 376

Cationic charge determines the distribution of liposomes between the vascular and extravascular compartments of tumors.

Campbell, R. B., Fukumura, D., Brown, E. B., Mazzola, L. M., Izumi, Y., Jain, R. K., Torchilin, V. P., & Munn, L. L. (2002) · PubMed · Cited by 372

Structures of lipid–DNA complexes: supramolecular assembly and gene delivery

Safinya, C. R. (2001) · Current Opinion in Structural Biology · doi:10.1016/s0959-440x(00)00230-x · Cited by 371

Cryogenic transmission electron microscopy (cryo-TEM) for studying the morphology of colloidal drug delivery systems

Kuntsche, J., Horst, J. C., & Bunjes, H. (2011) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2011.02.001 · Cited by 363

Multifunctional nanocarriers

Torchilin, V. P. (2012) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2012.09.031 · Cited by 356

Oxygen Radical-Mediated Pulmonary Toxicity Induced by Some Cationic Liposomes

Dokka, S., Toledo, D., Shi, X., Castranova, V., & Rojanasakul, Y. (2000) · Pharmaceutical Research · doi:10.1023/a:1007504613351 · Cited by 349

Liposomes as carriers of antigens and adjuvants

Alving, C. R. (1991) · Journal of Immunological Methods · doi:10.1016/0022-1759(91)90120-5 · Cited by 348

Nanopreparations to overcome multidrug resistance in cancer

Patel, N. R., Pattni, B. S., Abouzeid, A. H., & Torchilin, V. P. (2013) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2013.08.004 · Cited by 340

Design considerations for liposomal vaccines: Influence of formulation parameters on antibody and cell-mediated immune responses to liposome associated antigens

Watson, D. S., Endsley, A. N., & Huang, L. (2012) · Vaccine · doi:10.1016/j.vaccine.2012.01.070 · Cited by 339

Phospholipids and Lipid-Based Formulations in Oral Drug Delivery

Fricker, G., Kromp, T., Wendel, A., Blume, A., Zirkel, J., Rebmann, H., Setzer, C., Quinkert, R., Martin, F. J., & Müller-Goymann, C. C. (2010) · Pharmaceutical Research · doi:10.1007/s11095-010-0130-x · Cited by 338

Development and characterization of a novel Cremophor® EL free liposome-based paclitaxel (LEP-ETU) formulation

Zhang, J. A., Anyarambhatla, G., Ma, L., Ugwu, S. O., Xuan, T., Sardone, T., & Ahmad, I. N. (2004) · European Journal of Pharmaceutics and Biopharmaceutics · doi:10.1016/j.ejpb.2004.06.009 · Cited by 335

Effect of cholesterol and ethanol on dermal delivery from DPPC liposomes

López-Pinto, J. M., González-Rodrı́guez, M. L., & Rabasco, A. M. (2005) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2005.02.021 · Cited by 335

Bacterial inactivation by using near- and supercritical carbon dioxide

Dillow, A. K., Dehghani, F., Hrkach, J. S., Foster, N. R., & Langer, R. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.18.10344 · Cited by 331

Chemistry and biology of N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)-labeled lipids: fluorescent probes of biological and model membranes

Chattopadhyay, A. (1990) · Chemistry and Physics of Lipids · doi:10.1016/0009-3084(90)90128-e · Cited by 328

The Carrier Potential of Liposomes in Biology and Medicine

Gregoriadis, G. (1976) · New England Journal of Medicine · doi:10.1056/nejm197609302951406 · Cited by 325

Thermosensitive polymer-modified liposomes

Kono, K. (2001) · Advanced Drug Delivery Reviews · doi:10.1016/s0169-409x(01)00204-6 · Cited by 303

Application of Nanotechnology in Cosmetics

Li, M., & Sprando, R. L. (2010) · Pharmaceutical Research · doi:10.1007/s11095-010-0139-1 · Cited by 300

Tumor-targeted liposomes: doxorubicin-loaded long-circulating liposomes modified with anti-cancer antibody

Lukyanov, A. N., ElBayoumi, T. A., Chakilam, A. R., & Torchilin, V. P. (2004) · Journal of Controlled Release · doi:10.1016/j.jconrel.2004.08.007 · Cited by 294

Complexes between cationic liposomes and DNA visualized by cryo-TEM

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Nanoscale Drug Delivery and Hyperthermia: The Materials Design and Preclinical and Clinical Testing of Low Temperature-Sensitive Liposomes Used in Combination with Mild Hyperthermia in the Treatment of Local Cancer

Landon, C. D. (2011) · The Open Nanomedicine Journal · doi:10.2174/1875933501103010038 · Cited by 287

Cationic liposome-mediated delivery of siRNAs in adult mice

Sioud, M., & Sørensen, D. R. (2003) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2003.11.057 · Cited by 287

The effect of cholesterol and epicholesterol incorporation on the permeability and on the phase transition of intact Acholeplasma laidlawii cell membranes and derived liposomes

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Cell penetrating peptide-modified pharmaceutical nanocarriers for intracellular drug and gene delivery

Torchilin, V. P. (2008) · Peptide Science · doi:10.1002/bip.20989 · Cited by 283

Specific targeting with poly(ethylene glycol)-modified liposomes: coupling of homing devices to the ends of the polymeric chains combines effective target binding with long circulation times

Blume, G., Cevc, G., Crommelin, M. D. J. A., Bakker‐Woudenberg, I. A. J. M., Kluft, C., & Storm, G. (1993) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/0005-2736(93)90039-3 · Cited by 282

Liposomes loaded with paclitaxel and modified with novel triphenylphosphonium-PEG-PE conjugate possess low toxicity, target mitochondria and demonstrate enhanced antitumor effects in vitro and in vivo

Biswas, S., Dodwadkar, N. S., Deshpande, P. P., & Torchilin, V. P. (2012) · Journal of Controlled Release · doi:10.1016/j.jconrel.2012.01.009 · Cited by 281

Tumor-targeting dual peptides-modified cationic liposomes for delivery of siRNA and docetaxel to gliomas

Yang, Z., Li, J., Wang, Z.-Z., Dong, D., & Qi, X. (2014) · Biomaterials · doi:10.1016/j.biomaterials.2014.03.017 · Cited by 268

Targetability of novel immunoliposomes modified with amphipathic poly(ethylene glycol) s conjugated at their distal terminals to monoclonal antibodies

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Stimulus-responsive nanopreparations for tumor targeting

Zhu, L., & Torchilin, V. P. (2012) · Integrative Biology · doi:10.1039/c2ib20135f · Cited by 263

Filter extrusion of liposomes using different devices: comparison of liposome size, encapsulation efficiency, and process characteristics

Berger, N., Sachse, A., Bender, J., Schubert, R., & Brandl, M. (2001) · International Journal of Pharmaceutics · doi:10.1016/s0378-5173(01)00721-9 · Cited by 258

Thermoresponsive polymers: Insights into decisive hydrogel characteristics, mechanisms of gelation, and promising biomedical applications

Matanović, M. R., Kristl, J., & Grabnar, P. A. (2014) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2014.06.029 · Cited by 255

Phase I and pharmacokinetic study of MCC-465, a doxorubicin (DXR) encapsulated in PEG immunoliposome, in patients with metastatic stomach cancer

Matsumura, Y., Gotoh, M., Muro, K., Yamada, Y., Shirao, K., Shimada, Y., Okuwa, M., Matsumoto, S., Miyata, Y., Ohkura, H., et al. (2004) · Annals of Oncology · doi:10.1093/annonc/mdh092 · Cited by 253

Inhaled, dual release liposomal ciprofloxacin in non-cystic fibrosis bronchiectasis (ORBIT-2): a randomised, double-blind, placebo-controlled trial

Serisier, D. J., Bilton, D., Soyza, A. D., Thompson, P. J., Kolbe, J., Greville, H. W., Cipolla, D. C., Bruinenberg, P., Gonda, I., & the ORBIT-2 investigators (2013) · Thorax · doi:10.1136/thoraxjnl-2013-203207 · Cited by 249

Liposomal systems as drug delivery vehicles for dermal and transdermal applications

Pierre, M. B. R., & Costa, I. D. S. M. (2011) · Archives of Dermatological Research · doi:10.1007/s00403-011-1166-4 · Cited by 246

A novel liposomal adjuvant system, CAF01, promotes long-lived Mycobacterium tuberculosis-specific T-cell responses in human

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Nanotechnology and pulmonary delivery to overcome resistance in infectious diseases

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