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Drug-Loaded Biomimetic Carriers for Non-Hodgkin’s Lymphoma Therapy: Advances and Perspective

Li, Xiaoqi, Zhang, Yu, Wang, Chao, Wang, Liyuan, Ye, Yufu, Xue, Renyu, Shi, Yuanwei, Su, Quanping, Zhu, Yanxi, Wang, Lijuan·2024·ACS Biomaterials Science & Engineering
DOI 10.1021/acsbiomaterials.3c01480
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Abstract

Chemotherapy remains the mainstay of treatment for the lymphoma patient population, despite its relatively poor therapeutic results, high toxicity, and low specificity. With the advancement of biotechnology, the significance of drug-loading biomimetic materials in the medical field has become increasingly evident, attracting extensive attention from the scientific community and the pharmaceutical industry. Given that they can cater to the particular requirements of lymphoma patients, drug-loading biomimetic materials have recently become a potent and promising delivery approach for various applications. This review mainly reviews the recent advancements in the treatment of tumors with biological drug carrier-loaded drugs, outlines the mechanisms of lymphoma development and the diverse treatment modalities currently available, and discusses the merits and limitations of biological drug carriers. What is more, the practical application of biocarriers in tumors is explored by providing examples, and the possibility of loading such organisms with antilymphoma drugs for the treatment of lymphoma is conceived.

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Metadata

Authors
Li, X., Zhang, Y., Wang, C., Wang, L., Ye, Y., Xue, R., Shi, Y., Su, Q., Zhu, Y., & Wang, L.
Venue
ACS Biomaterials Science & Engineering
Publisher
American Chemical Society (ACS)
Published
2024-01-31
Volume
10
Issue
2
Pages
723-742
ISSN
2373-9878
DOI
10.1021/acsbiomaterials.3c01480
Cited by
4
References
3
Language
en
Licence
Funders
  • Medical and Health Science and Technology Development Project of Shandong Province (2019WS132)
  • Xuzhou Medical University (XYFZ202220, XYFZ202203)
  • Science and Technology Development Plan of Shandong Province (M-2023051)
  • Natural Science Foundation of Shandong Province (ZR2022MH058)
  • Natural Science Foundation of Zhejiang Province (LZ22H030003)
  • Linyi key Research Project (2022YX0011)
  • Linyi key research and development plan (2022YX0052)

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