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Inhibitor Mimetic Mutations in the Pseudomonas aeruginosa PqsE Enzyme Reveal a Protein–Protein Interaction with the Quorum-Sensing Receptor RhlR That Is Vital for Virulence Factor Production
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“Another key effector of the PQS system is the PqsE protein, which is required for full virulence in P. aeruginosa via a mechanism probably involving direct interaction with RhlR33,36,37.”
From Pseudomonas aeruginosa: ecology, evolution, pathogenesis and antimicrobial susceptibility (2025) · cites this paper as [37]
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Research works printed but not linked: 45
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Cited by
Pseudomonas aeruginosa: ecology, evolution, pathogenesis and antimicrobial susceptibility
Letizia, M., Diggle, S. P., & Whiteley, M. (2025) · Nature Reviews Microbiology · doi:10.1038/s41579-025-01193-8 · Cited by 231
(2023) · doi:10.1038/s41467-023-43702-4 · Cited by 55
Metadata
- Authors
- Taylor, I. R., Paczkowski, J. E., Jeffrey, P. D., Henke, B. R., Smith, C. D., & Bassler, B. L.
- Venue
- ACS Chemical Biology
- Publisher
- American Chemical Society (ACS)
- Published
- 2021-04-01
- Volume
- 16
- Issue
- 4
- Pages
- 740-752
- ISSN
- 1554-8929
- 1554-8937
- Cited by
- 72
- References
- 0
- Language
- en
- Funders
- Howard Hughes Medical Institute
- Division of Molecular and Cellular Biosciences (MCB-1713731)
- National Institute of General Medical Sciences (2R37GM065859, F32GM134583)
- New York Community Trust Foundation (P19-000454)
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- This page
- CoChat. (2026). Citation check: Inhibitor Mimetic Mutations in the Pseudomonas aeruginosa PqsE Enzyme Reveal a Protein–Protein Interaction with the Quorum-Sensing Receptor RhlR That Is Vital for Virulence Factor Production. https://app.cochat.ai/papers/10.1021/acschembio.1c00049
- The paper
- Taylor, I. R., Paczkowski, J. E., Jeffrey, P. D., Henke, B. R., Smith, C. D., & Bassler, B. L. (2021). Inhibitor Mimetic Mutations in the Pseudomonas aeruginosa PqsE Enzyme Reveal a Protein–Protein Interaction with the Quorum-Sensing Receptor RhlR That Is Vital for Virulence Factor Production. ACS Chemical Biology. https://doi.org/10.1021/acschembio.1c00049
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.