Glutathione Peroxidase: The Primary Agent for the Elimination of Hydrogen Peroxide in Erythrocytes*
Abstract
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTGlutathione Peroxidase: The Primary Agent for the Elimination of Hydrogen Peroxide in Erythrocytes*Gerald Cohen and Paul HochsteinCite this: Biochemistry 1963, 2, 6, 1420–1428Publication Date (Print):November 1, 1963Publication History Published online1 May 2002Published inissue 1 November 1963https://pubs.acs.org/doi/10.1021/bi00906a038https://doi.org/10.1021/bi00906a038research-articleACS PublicationsRequest reuse permissionsArticle Views928Altmetric-Citations530LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
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In nonpathological conditions, glutathione peroxidase is the enzyme degrading most of the H2O2 by oxidizing reduced GSH into GSSG.
“In nonpathological conditions, GPx has been shown to be the enzyme degrading most of the H2O2 by oxidizing reduced GSH into GSSG (Eq. 10).”
From Red Blood Cell Function and Dysfunction: Redox Regulation, Nitric Oxide Metabolism, Anemia (2017) · cites this paper as [38]
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- Authors
- Cohen, G., & Hochstein, P.
- Venue
- Biochemistry
- Publisher
- American Chemical Society (ACS)
- Published
- 1963-11-01
- Volume
- 2
- Issue
- 6
- Pages
- 1420-1428
- ISSN
- 0006-2960 (ISSN-L)
- 1520-4995
- OpenAlex
- W2053985315
- Cited by
- 666
- References
- 16
- Citations by year
- 2026: 1 · 2025: 4 · 2024: 9 · 2023: 8 · 2022: 6 · 2021: 6 · 2020: 4 · 2019: 6 · 2018: 6 · 2017: 6 · 2016: 10 · 2015: 14 · 2014: 13 · 2013: 9 · 2012: 8
- FWCI
- 6.12
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Biochemistry (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Redox biology and oxidative stress
- Health Sciences › Nursing › Nutrition and Dietetics › Selenium in Biological Systems
- Health Sciences › Medicine › Biochemistry › Antioxidant Activity and Oxidative Stress
- Keywords
- glutathione peroxidase, hydrogen peroxide, erythrocytes, antioxidant enzymes, erythrocyte metabolism
- MeSH terms
- Animals, Biological Transport, Catalase, Erythrocytes, Glutathione, Glutathione Peroxidase, Hemolysis, Hydrogen Peroxide, Metabolism, Methemoglobin, Peroxidases, Poultry, Research, Cell Death
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