The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Phthalates, Alkylphenols, Pesticides, Polybrominated Diphenyl Ethers, and Other Endocrine-Disrupting Compounds in Indoor Air and Dust
Abstract
Chemicals identified as endocrine-disrupting compounds (EDCs) have widespread consumer uses, yet little is known about indoor exposure. We sampled indoor air and dust in 120 homes, analyzing for 89 organic chemicals identified as EDCs. Fifty-two compounds were detected in air and 66 were detected in dust. These are the first reported measures in residential environments for over 30 of the compounds, including several detected at the highest concentrations. The number of compounds detected per home ranged from 13 to 28 in air and from 6 to 42 in dust. The most abundant compounds in air included phthalates (plasticizers, emulsifiers), o-phenylphenol (disinfectant), 4-nonylphenol (detergent metabolite), and 4-tert-butylphenol (adhesive) with typical concentrations in the range of 50-1500 ng/m3. The penta- and tetrabrominated diphenyl ethers (flame retardants) were frequently detected in dust, and 2,3-dibromo-1-propanol, the carcinogenic intermediate of a flame retardant banned in 1977, was detected in air and dust. Twenty-three pesticides were detected in air and 27 were detected in dust, the most abundant being permethrins and the synergist piperonyl butoxide. The banned pesticides heptachlor, chlordane, methoxychlor, and DDT were also frequently detected, suggesting limited indoor degradation. Detected concentrations exceeded government health-based guidelines for 15 compounds, but no guidelines are available for 28 compounds, and existing guidelines do not consider endocrine effects. This study provides a basis for prioritizing toxicology and exposure research for individual EDCs and mixtures and provides new tools for exposure assessment in health studies.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Kolpin, D. W., Furlong, E. T., Meyer, M. T., Thurman, E. M., Zaugg, S. D., Barber, L. B., & Buxton, H. T. (2002) · Environmental Science & Technology · doi:10.1021/es011055j · Cited by 7,953
Levels of Seven Urinary Phthalate Metabolites in a Human Reference Population
Blount, B. C., Silva, M. J., Caudill, S. P., Needham, L. L., Pirkle, J. L., Sampson, E. J., Lucier, G. W., Jackson, R. J., & Brock, J. W. (2000) · Environmental Health Perspectives · doi:10.1289/ehp.00108979 · Cited by 634
Cited by
Endocrine-Disrupting Chemicals: An Endocrine Society Scientific Statement
Diamanti-Kandarakis, E., Bourguignon, J.-P., Giudice, L. C., Hauser, R., Prins, G. S., Soto, A. M., Zoeller, R. T., & Gore, A. C. (2009) · Endocrine Reviews · doi:10.1210/er.2009-0002 · Cited by 4,585
Airborne microplastics: consequences to human health?
Prata, J. C. (2018) · Environmental Pollution · doi:10.1016/j.envpol.2017.11.043 · Cited by 1,852
What are the sources of exposure to eight frequently used phthalic acid esters in Europeans?
Wormuth, M., Scheringer, M., Vollenweider, M., & Hungerbühler, K. (2006) · Risk Analysis · doi:10.1111/j.1539-6924.2006.00770.x · Cited by 1,025
Farré, M. L., Pérez, S., Kantiani, L., & Barceló, D. (2008) · TrAC Trends in Analytical Chemistry · doi:10.1016/j.trac.2008.09.010 · Cited by 1,009
Hauser, R., & Calafat, A. M. (2005) · Occupational and Environmental Medicine · doi:10.1136/oem.2004.017590 · Cited by 941
Bornehag, C.-G., Sundell, J., Weschler, C. J., Sigsgaard, T., Lundgren, B., Hasselgren, M., & Hägerhed-Engman, L. (2004) · Environmental Health Perspectives · doi:10.1289/ehp.7187 · Cited by 851
Semivolatile organic compounds in indoor environments
Weschler, C. J., & Nazaroff, W. W. (2008) · Atmospheric Environment · doi:10.1016/j.atmosenv.2008.09.052 · Cited by 850
Cleaning products and air fresheners: exposure to primary and secondary air pollutants
Nazaroff, W. W., & Weschler, C. J. (2004) · Atmospheric Environment · doi:10.1016/j.atmosenv.2004.02.040 · Cited by 846
Phthalates and other additives in plastics: human exposure and associated health outcomes
Meeker, J. D., Sathyanarayana, S., & Swan, S. H. (2009) · Philosophical Transactions of the Royal Society B: Biological Sciences · doi:10.1098/rstb.2008.0268 · Cited by 835
The Complex Interaction between Marine Debris and Toxic Chemicals in the Ocean
Engler, R. E. (2012) · Environmental Science & Technology · doi:10.1021/es3027105 · Cited by 773
Corrales, J., Kristofco, L. A., Steele, W. B., Yates, B. S., Breed, C. S., Williams, E. S., & Brooks, B. W. (2015) · Dose-Response · doi:10.1177/1559325815598308 · Cited by 771
Deep Dive into Plastic Monomers, Additives, and Processing Aids
Wiesinger, H., Wang, Z., & Hellweg, S. (2021) · Environmental Science & Technology · doi:10.1021/acs.est.1c00976 · Cited by 724
Temporal Variability of Urinary Phthalate Metabolite Levels in Men of Reproductive Age
Hauser, R., Meeker, J. D., Park, S., Silva, M. J., & Calafat, A. M. (2004) · Environmental Health Perspectives · doi:10.1289/ehp.7212 · Cited by 473
SVOC exposure indoors: fresh look at dermal pathways: SVOC exposure via dermal pathways
Weschler, C. J., & Nazaroff, W. W. (2012) · Indoor Air · doi:10.1111/j.1600-0668.2012.00772.x · Cited by 422
Widespread Occurrence of Bisphenol A in Paper and Paper Products: Implications for Human Exposure
Liao, C., & Kannan, K. (2011) · Environmental Science & Technology · doi:10.1021/es202507f · Cited by 392
SVOC partitioning between the gas phase and settled dust indoors
Weschler, C. J., & Nazaroff, W. W. (2010) · Atmospheric Environment · doi:10.1016/j.atmosenv.2010.06.029 · Cited by 371
Analysis of phthalates in food products and packaging materials sold on the Belgian market
Fierens, T., Servaes, K., Van Holderbeke, M., Geerts, L., De Henauw, S., Sioen, I., & Vanermen, G. (2012) · Food and Chemical Toxicology · doi:10.1016/j.fct.2012.04.029 · Cited by 366
Environmental pollutants and breast cancer: Epidemiologic studies
Brody, J. G., Moysich, K. B., Humblet, O., Attfield, K. R., Beehler, G. P., & Rudel, R. A. (2007) · Cancer · doi:10.1002/cncr.22655 · Cited by 375
Self-citationLucattini, L., Poma, G., Covaci, A., de Boer, J., Lamoree, M. H., & Leonards, P. E. G. (2018) · Chemosphere · doi:10.1016/j.chemosphere.2018.02.161 · Cited by 359
Schecter, A., Päpke, O., Tung, K. C., Joseph, J., Harris, T. R., & Dahlgren, J. (2005) · Journal of Occupational and Environmental Medicine · doi:10.1097/01.jom.0000158704.27536.d2 · Cited by 329
Plastics additives in the indoor environment—flame retardants and plasticizers
Wensing, M., Uhde, E., & Salthammer, T. (2005) · Science of The Total Environment · doi:10.1016/j.scitotenv.2004.10.028 · Cited by 317
Organic Contamination of Settled House Dust, A Review for Exposure Assessment Purposes
Mercier, F., Glorennec, P., Thomas, O., & Bot, B. L. (2011) · Environmental Science & Technology · doi:10.1021/es200925h · Cited by 255
Overview of air pollution and endocrine disorders
Darbre, P. (2018) · International Journal of General Medicine · doi:10.2147/ijgm.s102230 · Cited by 248
Peck, A. M. (2006) · Analytical and Bioanalytical Chemistry · doi:10.1007/s00216-006-0728-3 · Cited by 254
Hines, E. P., Calafat, A. M., Silva, M. J., Mendola, P., & Fenton, S. E. (2009) · Environmental Health Perspectives · doi:10.1289/ehp.11610 · Cited by 232
Zota, A. R., Rudel, R. A., Morello-Frosch, R. A., & Brody, J. G. (2008) · Environmental Science & Technology · doi:10.1021/es801792z · Cited by 227
Self-citationWeschler, C. J., Bekö, G., Koch, H. M., Salthammer, T., Schripp, T., Toftum, J., & Clausen, G. (2015) · Environmental Health Perspectives · doi:10.1289/ehp.1409151 · Cited by 209
Lee, H., Jeung, E., Cho, M., Kim, T., Leung, P. C. K., & Choi, K. (2013) · Journal of Cellular and Molecular Medicine · doi:10.1111/j.1582-4934.2012.01649.x · Cited by 171
Why Endocrine Disrupting Chemicals (EDCs) Challenge Traditional Risk Assessment and How to Respond
Futran Fuhrman, V., Tal, A., & Arnon, S. (2015) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2014.12.012 · Cited by 152
Tran, T. M., & Kannan, K. (2015) · Archives of Environmental Contamination and Toxicology · doi:10.1007/s00244-015-0140-0 · Cited by 151
Wójtowicz, A. K., Szychowski, K. A., Wnuk, A., & Kajta, M. (2017) · Neurotoxicity Research · doi:10.1007/s12640-016-9665-x · Cited by 129
Ouyang, X., Weiss, J. M., de Boer, J., Lamoree, M. H., & Leonards, P. E. G. (2017) · Chemosphere · doi:10.1016/j.chemosphere.2016.09.107 · Cited by 68
Healy, B. F., English, K. R., Jagals, P., & Sly, P. D. (2015) · Journal of Exposure Science & Environmental Epidemiology · doi:10.1038/jes.2015.49 · Cited by 59
Crane, J. L. (2019) · Archives of Environmental Contamination and Toxicology · doi:10.1007/s00244-019-00598-w · Cited by 26
Metadata
- Authors
- Rudel, R. A., Camann, D. E., Spengler, J. D., Korn, L. R., & Brody, J. G.
- Venue
- Environmental Science & Technology
- Publisher
- American Chemical Society (ACS)
- Published
- 2003-09-13
- Volume
- 37
- Issue
- 20
- Pages
- 4543-4553
- ISSN
- 0013-936X (ISSN-L)
- 1520-5851
- OpenAlex
- W2071591569
- Cited by
- 1,055
- References
- 2
- FWCI
- 22.15
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.