The DOI matches its Crossref record; 8 of the 8 references it cites were found in a registry or an index.
Polyfluoroalkyl Chemicals in Pooled Blood Serum from Infants, Children, and Adults in Australia
Abstract
Polyfluoroalkyl chemicals (PFCs) have been used worldwide for more than 50 years in a wide variety of industrial and consumer products. Limited data exist on human exposure to PFCs in the Southern Hemisphere. Human blood serum collected in southeast Queensland, Australia, in 2006-2007 from 2420 donors was pooled according to age (cord blood, 0-0.5, 0.6-1, 1.1-1.5, 1.6-2, 2.1-2.5, 2.6-3, 3.1-3.5, 3.6-4, 4.1-6, 6.1-9, 9.1-12, 12.1-15, 16-30, 31-45, 46-60, and > 60 years) and gender and was analyzed for eight PFCs. Across all pools, perfluorooctane sulfonate (PFOS) was detected at the highest mean concentration (15.2 ng/mL) followed by perfluorooctanoate (PFOA, 6.4 ng/mL), perfluorohexane sulfonate (PFHxS, 3.1 ng/mL), perfluorononanoate (PFNA, 0.8 ng/mL), 2-(N-methylperfluorooctance sulfonamide) acetate (Me-PFOSA-AcOH, 0.66 ng/mL), and perfluorodecanoate (PFDeA, 0.29 ng/mL). Perfluorooctane sulfonamide was detected in only 24% of the pools, and 2-(N-ethylperfluorooctane sulfonamide) acetate was detected in only one. PFOS concentrations were significantly higher in pools from adult males than from adult females (p = 0.002); no gender differences were apparent in the pools from children (< 12 years old). The highest mean concentrations of PFOA, PFHxS, PFNA, PFDeA, and Me-PFOSA-AcOH were found in children < 15 years, while PFOS was highest in adults > 60 years. Investigation into the sources and exposure pathways in Australia, in particular for children, is necessary as well as continued biomonitoring to determine the potential effects on human concentrations as a result of changes in the PFC manufacturing practices, including the cessation of production of several PFCs.
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Cites
Global Distribution of Perfluorooctane Sulfonate in Wildlife
Giesy, J. P., & Kannan, K. (2001) · Environmental Science & Technology · doi:10.1021/es001834k · Cited by 2,750
Perfluoroalkyl Acids: A Review of Monitoring and Toxicological Findings
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Calafat, A. M., Wong, L.-Y., Kuklenyik, Z., Reidy, J. A., & Needham, L. L. (2007) · Environmental Health Perspectives · doi:10.1289/ehp.10598 · Cited by 1,247
Self-citationPerfluorooctanesulfonate and related fluorochemicals in human blood from several countries
Kannan, K., Corsolini, S., Falandysz, J., Fillmann, G., Kumar, K. S., Loganathan, B. G., Mohd, M. A., Olivero, J., Wouwe, N. V., Yang, J. H., et al. (2004) · Environmental Science & Technology · doi:10.1021/es0493446 · Cited by 1,056
The toxicology of perfluorooctanoate
Kennedy, G. L., Butenhoff, J. L., Olsen, G. W., O'Connor, J. C., Seacat, A. M., Perkins, R. G., Biegel, L. B., Murphy, S. R., & Farrar, D. G. (2004) · Critical Reviews in Toxicology · doi:10.1080/10408440490464705 · Cited by 742
Olsen, G. W., Mair, D. C., Church, T. R., Ellefson, M. E., Reagen, W. K., Boyd, T. M., Herron, R. M., Medhdizadehkashi, Z., Nobiletti, J. B., Rios, J. A., et al. (2008) · Environmental Science & Technology · doi:10.1021/es800071x · Cited by 244
Perfluorinated Compounds in House Dust from Ohio and North Carolina, USA
Strynar, M. J., & Lindstrom, A. B. (2008) · Environmental Science & Technology · doi:10.1021/es7032058 · Cited by 205
Cited by
Buck, R. C., Franklin, J., Berger, U., Conder, J. M., Cousins, I. T., de Voogt, P., Jensen, A. A., Kannan, K., Mabury, S. A., & van Leeuwen, S. P. (2011) · Integrated Environmental Assessment and Management · doi:10.1002/ieam.258 · Cited by 4,641
Post, G. B., Cohn, P. D., & Cooper, K. R. (2012) · Environmental Research · doi:10.1016/j.envres.2012.03.007 · Cited by 639
Comparing the toxic potency in vivo of long-chain perfluoroalkyl acids and fluorinated alternatives
Gomis, M. I., Vestergren, R., Borg, D., & Cousins, I. T. (2018) · Environment International · doi:10.1016/j.envint.2018.01.011 · Cited by 438
Haug, L. S., Huber, S., Becher, G., & Thomsen, C. (2011) · Environment International · doi:10.1016/j.envint.2011.01.011 · Cited by 391
Coggan, T. L., Moodie, D., Kolobaric, A., Szabo, D., Shimeta, J., Crosbie, N. D., Lee, E., Fernandes, M., & Clarke, B. O. (2019) · Heliyon · doi:10.1016/j.heliyon.2019.e02316 · Cited by 327
Metadata
- Authors
- Toms, L.-M. L., Calafat, A. M., Kato, K., Thompson, J., Harden, F., Hobson, P., Sjödin, A., & Mueller, J. F.
- Venue
- Environmental Science & Technology
- Publisher
- American Chemical Society (ACS)
- Published
- 2009-04-27
- Volume
- 43
- Issue
- 11
- Pages
- 4194-4199
- ISSN
- 0013-936X (ISSN-L)
- 1520-5851
- OpenAlex
- W2003916723
- Cited by
- 169
- References
- 8
- FWCI
- 15.86
- Type
- journal article
- Language
- en
- Open access
- closed
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- Toms, L.-M. L., Calafat, A. M., Kato, K., Thompson, J., Harden, F., Hobson, P., Sjödin, A., & Mueller, J. F. (2009). Polyfluoroalkyl Chemicals in Pooled Blood Serum from Infants, Children, and Adults in Australia. Environmental Science & Technology. https://doi.org/10.1021/es900272u
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