The DOI matches its Crossref record; 10 of the 10 references it cites were found in a registry or an index.
Controlled Vesicle Self-Assembly in Microfluidic Channels with Hydrodynamic Focusing
Abstract
Traditional liposome preparation methods are based on mixing of bulk phases, leading to inhomogeneous chemical and/or mechanical conditions during formation; hence liposomes are often polydisperse in size and lamellarity. Here we show the formation of liposomes that encapsulate reagents in a continuous two-phase flow microfluidic network with precision control of size from 100 to 300 nm by manipulation of liquid flow rates. We demonstrate that by creating a solvent-aqueous interfacial region in a microfluidic format that is homogeneous and controllable on the length scale of a liposome, we can facilitate the fine control of liposome size and polydispersity.
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Cites
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Microfabrication Inside Capillaries Using Multiphase Laminar Flow Patterning
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Cited by
New developments in liposomal drug delivery
Pattni, B. S., Chupin, V. V., & Torchilin, V. P. (2015) · Chemical Reviews · doi:10.1021/acs.chemrev.5b00046 · Cited by 1,600
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Recent advancements in liposome technology
Filipczak, N., Pan, J., Yalamarty, S. S. K., & Torchilin, V. P. (2020) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2020.06.022 · Cited by 592
Microfluidic methods for forming liposomes
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Polymeric Delivery of Therapeutic Nucleic Acids
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Metadata
- Authors
- Jahn, A., Vreeland, W. N., Gaitan, M., & Locascio, L. E.
- Venue
- Journal of the American Chemical Society
- Publisher
- American Chemical Society (ACS)
- Published
- 2004-02-17
- Volume
- 126
- Issue
- 9
- Pages
- 2674-2675
- ISSN
- 0002-7863 (ISSN-L)
- 1520-5126
- OpenAlex
- W2009858479
- Cited by
- 537
- References
- 10
- FWCI
- 7.32
- Type
- journal article
- Language
- en
- Open access
- closed
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- Jahn, A., Vreeland, W. N., Gaitan, M., & Locascio, L. E. (2004). Controlled Vesicle Self-Assembly in Microfluidic Channels with Hydrodynamic Focusing. Journal of the American Chemical Society. https://doi.org/10.1021/ja0318030
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
