The DOI matches its Crossref record; 37 of the 37 references it cites were found in a registry or an index.
Development of Highly Sensitive Fluorescent Probes for Detection of Intracellular Copper(I) in Living Systems
Abstract
We describe here the new copper-selective fluorescent probes FluTPA1 and FluTPA2, in which the tetradentate ligand tris[(2-pyridyl)methyl]amine (TPA) is connected to a reduced form of a fluorescein platform through a benzyl ether linkage. These probes selectively react with copper ions in the presence of submillimolar glutathione and emit intense green fluorescence from the reaction product, O-methylfluorescein. Confocal images of live cells further show that FluTPA2 is membrane-permeable and allows visualization of Cu(I) present in living cells.
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Cites
Signaling Recognition Events with Fluorescent Sensors and Switches
de Silva, A. P., Gunaratne, H. Q. N., Gunnlaugsson, T., Huxley, A. J. M., McCoy, C. P., Rademacher, J. T., & Rice, T. E. (1997) · Chemical Reviews · doi:10.1021/cr960386p · Cited by 6,995
Meister, A., & Anderson, M. E. (1983) · Annual Review of Biochemistry · doi:10.1146/annurev.bi.52.070183.003431 · Cited by 5,680
Oxygen toxicity, oxygen radicals, transition metals and disease
Halliwell, B., & Gutteridge, J. M. C. (1984) · Biochemical Journal · doi:10.1042/bj2190001 · Cited by 5,330
Metals in Neurobiology: Probing Their Chemistry and Biology with Molecular Imaging
Que, E. L., Domaille, D. W., & Chang, C. J. (2008) · Chemical Reviews · doi:10.1021/cr078203u · Cited by 2,061
The Wilson disease gene is a putative copper transporting P–type ATPase similar to the Menkes gene
Bull, P. C., Thomas, G. R., Rommens, J. M., Forbes, J. R., & Cox, D. W. (1993) · Nature Genetics · doi:10.1038/ng1293-327 · Cited by 1,948
Rae, T. D., Schmidt, P. J., Pufahl, R. A., Culotta, V. C., & V. O'Halloran, T. (1999) · Science · doi:10.1126/science.284.5415.805 · Cited by 1,629
Copper biochemistry and molecular biology
Linder, M. C., & Hazegh-Azam, M. (1996) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/63.5.797 · Cited by 1,430
Vulpe, C., Levinson, B., Whitney, S., Packman, S., & Gitschier, J. (1993) · Nature Genetics · doi:10.1038/ng0193-7 · Cited by 1,418
Synthetic fluorescent sensors for studying the cell biology of metals
Domaille, D. W., Que, E. L., & Chang, C. J. (2008) · Nature Chemical Biology · doi:10.1038/nchembio.69 · Cited by 1,081
Jung, H. S., Kwon, P. S., Lee, J. W., Kim, J. I., Hong, C. S., Kim, J. W., Yan, S., Lee, J. Y., Lee, J. H., Joo, T., et al. (2009) · Journal of the American Chemical Society · doi:10.1021/ja808611d · Cited by 1,058
Jiang, P., & Guo, Z. (2004) · Coordination Chemistry Reviews · doi:10.1016/j.cct.2003.10.013 · Cited by 989
A Selective Turn-On Fluorescent Sensor for Imaging Copper in Living Cells
Zeng, L., Miller, E. W., Pralle, A., Isacoff, E. Y., & Chang, C. J. (2006) · Journal of the American Chemical Society · doi:10.1021/ja055064u · Cited by 806
A Ratiometric Fluorescent Probe Based on FRET for Imaging Hg 2+ Ions in Living Cells
Zhang, X., Xiao, Y., & Qian, X. (2008) · Angewandte Chemie International Edition · doi:10.1002/anie.200803246 · Cited by 800
Evolution of Fluorescein as a Platform for Finely Tunable Fluorescence Probes
Urano, Y., Kamiya, M., Kanda, K., Ueno, T., Hirose, K., & Nagano, T. (2005) · Journal of the American Chemical Society · doi:10.1021/ja043919h · Cited by 683
Molecular Basis of Metal-Ion Selectivity and Zeptomolar Sensitivity by CueR
Changela, A., Chen, K., Xue, Y., Holschen, J., Outten, C. E., O'Halloran, T. V., & Mondragón, A. (2003) · Science · doi:10.1126/science.1085950 · Cited by 660
Liu, J., & Lu, Y. (2007) · Journal of the American Chemical Society · doi:10.1021/ja0717358 · Cited by 647
A Selective Fluorescent Sensor for Imaging Cd2+ in Living Cells
Peng, X., Du, J., Fan, J., Wang, J., Wu, Y., Zhao, J., Sun, S., & Xu, T. (2007) · Journal of the American Chemical Society · doi:10.1021/ja0643319 · Cited by 617
Misfolded CuZnSOD and amyotrophic lateral sclerosis
Valentine, J. S., & Hart, P. J. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0730423100 · Cited by 546
In Vivo Monitoring of Mercury Ions Using a Rhodamine-Based Molecular Probe
Ko, S.-K., Yang, Y.-K., Tae, J., & Shin, I. (2006) · Journal of the American Chemical Society · doi:10.1021/ja065114a · Cited by 509
Screening Mercury Levels in Fish with a Selective Fluorescent Chemosensor
Yoon, S., Albers, A. E., Wong, A. P., & Chang, C. J. (2005) · Journal of the American Chemical Society · doi:10.1021/ja0557987 · Cited by 503
Copper in the brain and Alzheimer’s disease
Hung, Y. H., Bush, A. I., & Cherny, R. A. (2010) · JBIC Journal of Biological Inorganic Chemistry · doi:10.1007/s00775-009-0600-y · Cited by 498
Turn-On and Ratiometric Mercury Sensing in Water with a Red-Emitting Probe
Nolan, E. M., & Lippard, S. J. (2007) · Journal of the American Chemical Society · doi:10.1021/ja068879r · Cited by 428
Ratiometric Displacement Approach to Cu(II) Sensing by Fluorescence
Royzen, M., Dai, Z., & Canary, J. W. (2005) · Journal of the American Chemical Society · doi:10.1021/ja0431051 · Cited by 415
Klinman, J. P. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.r500011200 · Cited by 394
Yang, L., McRae, R., Henary, M. M., Patel, R., Lai, B., Vogt, S., & Fahrni, C. J. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0406547102 · Cited by 383
Cheng, T., Xu, Y., Zhang, S., Zhu, W., Qian, X., & Duan, L. (2008) · Journal of the American Chemical Society · doi:10.1021/ja806928n · Cited by 339
Zhou, Z., & Fahrni, C. J. (2004) · Journal of the American Chemical Society · doi:10.1021/ja049684r · Cited by 329
Zinc sensing for cellular application
Kikuchi, K., Komatsu, K., & Nagano, T. (2004) · Current Opinion in Chemical Biology · doi:10.1016/j.cbpa.2004.02.007 · Cited by 320
Yu, M., Shi, M., Chen, Z., Li, F., Li, X., Gao, Y., Xu, J., Yang, H., Zhou, Z., Yi, T., et al. (2008) · Chemistry – A European Journal · doi:10.1002/chem.200800005 · Cited by 303
Chen, P., & Solomon, E. I. (2004) · Journal of the American Chemical Society · doi:10.1021/ja031564g · Cited by 251
Viguier, R. F. H., & Hulme, A. N. (2006) · Journal of the American Chemical Society · doi:10.1021/ja064232v · Cited by 224
Fluorescence Imaging of Intracellular Cadmium Using a Dual-Excitation Ratiometric Chemosensor
Taki, M., Desaki, M., Ojida, A., Iyoshi, S., Hirayama, T., Hamachi, I., & Yamamoto, Y. (2008) · Journal of the American Chemical Society · doi:10.1021/ja803429z · Cited by 203
Self-citationBurdette, S. C., & Lippard, S. J. (2001) · Coordination Chemistry Reviews · doi:10.1016/s0010-8545(01)00308-3 · Cited by 148
Fujikawa, Y., Urano, Y., Komatsu, T., Hanaoka, K., Kojima, H., Terai, T., Inoue, H., & Nagano, T. (2008) · Journal of the American Chemical Society · doi:10.1021/ja802423n · Cited by 146
Jun, E. J., Won, H. N., Kim, J. S., et al. (2006) · Tetrahedron Letters · doi:10.1016/j.tetlet.2006.04.143 · Cited by 104
Fluorescent Sensor for Cu2+ with a Tunable Emission Wavelength
Mokhir, A. A., Kiel, A., Herten, D., & Kraemer, R. (2005) · Inorganic Chemistry · doi:10.1021/ic050362d · Cited by 102
A selective fluorescent sensor for imaging Cu2+ in living cells
Jiao, L., Li, J., Zhang, S., Wei, C., Hao, E., & Vicente, M. G. H. (2009) · New Journal of Chemistry · doi:10.1039/b906441a · Cited by 92
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Reaction-based small-molecule fluorescent probes for chemoselective bioimaging
Chan, J., Dodani, S. C., & Chang, C. J. (2012) · Nature Chemistry · doi:10.1038/nchem.1500 · Cited by 1,883
Du, J., Hu, M., Fan, J., & Peng, X. (2012) · Chemical Society Reviews · doi:10.1039/c2cs00004k · Cited by 688
Synthetic fluorescent probes for studying copper in biological systems
Cotruvo, Jr., Aron, A. T., Ramos-Torres, K. M., & Chang, C. J. (2015) · Chemical Society Reviews · doi:10.1039/c4cs00346b · Cited by 558
“Turn-on” fluorescent sensing with “reactive” probes
Eun Jun, M., Roy, B., & Han Ahn, K. (2011) · Chemical Communications · doi:10.1039/c1cc00014d · Cited by 434
A highly selective turn-on fluorescent probe for iron(ii) to visualize labile iron in living cells
Hirayama, T., Okuda, K., & Nagasawa, H. (2013) · Chemical Science · doi:10.1039/c2sc21649c · Cited by 296
Metadata
- Authors
- Taki, M., Iyoshi, S., Ojida, A., Hamachi, I., & Yamamoto, Y.
- Venue
- Journal of the American Chemical Society
- Publisher
- American Chemical Society (ACS)
- Published
- 2010-04-08
- Volume
- 132
- Issue
- 17
- Pages
- 5938-5939
- ISSN
- 0002-7863 (ISSN-L)
- 1520-5126
- OpenAlex
- W2003595893
- Cited by
- 253
- References
- 37
- FWCI
- 8.15
- Type
- journal article
- Language
- en
- Open access
- closed
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