The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.
Functional Gold Nanoparticles as Potent Antimicrobial Agents against Multi-Drug-Resistant Bacteria
Open accessAbstract
We present the use of functionalized gold nanoparticles (AuNPs) to combat multi-drug-resistant pathogenic bacteria. Tuning of the functional groups on the nanoparticle surface provided gold nanoparticles that were effective against both Gram-negative and Gram-positive uropathogens, including multi-drug-resistant pathogens. These AuNPs exhibited low toxicity to mammalian cells, and bacterial resistance was not observed after 20 generations. A strong structure-activity relationship was observed as a function of AuNP functionality, providing guidance to activity prediction and rational design of effective antimicrobial nanoparticles.
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Cites
Nanocarriers as an emerging platform for cancer therapy
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Nanoparticle therapeutics: an emerging treatment modality for cancer
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Klevens, R. M. (2007) · JAMA · doi:10.1001/jama.298.15.1763 · Cited by 3,726 · cited 1×
“Particularly, MRSA has emerged as “superbug”, resistant to most antibiotics commonly used for the staph infections.(30) NP 3 was effective in treating each of these pathogens, with MICs of 8 64 nM.”
BackgroundThe crisis in antibiotic resistance
Neu, H. C. (1992) · Science · doi:10.1126/science.257.5073.1064 · Cited by 2,834 · cited 1×
“T he emergence of multi-drug-resistant (MDR) bacteria has become a severe threat to public health.(1) According to”
BackgroundApplications of Nanoparticles in Biology
De, M., Ghosh, P. S., & Rotello, V. M. (2008) · Advanced Materials · doi:10.1002/adma.200703183 · Cited by 1,547
Self-citationTrends in antimicrobial drug development: Implications for the future
Spellberg, B., Powers, J. H., Brass, E. P., Miller, L. G., & Edwards, J. E. (2004) · Clinical Infectious Diseases · doi:10.1086/420937 · Cited by 867
Cited by
Combatting antibiotic-resistant bacteria using nanomaterials
Gupta, A., Mumtaz, S., Li, C.-H., Hussain, I., & Rotello, V. M. (2019) · Chemical Society Reviews · doi:10.1039/c7cs00748e · Cited by 1,115
Self-citationAntimicrobial Activity of Metal and Metal‐Oxide Based Nanoparticles
Gold, K., Slay, B., Knackstedt, M., & Gaharwar, A. K. (2018) · Advanced Therapeutics · doi:10.1002/adtp.201700033 · Cited by 758
Nanotechnology-based antimicrobials and delivery systems for biofilm-infection control
Liu, Y., Shi, L., Su, L., van der Mei, H. C., Jutte, P. C., Ren, Y., & Busscher, H. J. (2019) · Chemical Society Reviews · doi:10.1039/c7cs00807d · Cited by 737
Antibacterial properties and toxicity from metallic nanomaterials
Vimbela, G., Ngo, S. M., Fraze, C., Yang, L., & Stout, D. A. (2017) · International Journal of Nanomedicine · doi:10.2147/ijn.s134526 · Cited by 640
Antimicrobial Gold Nanoclusters
Zheng, K., Setyawati, M. I., Leong, D. T., & Xie, J. (2017) · ACS Nano · doi:10.1021/acsnano.7b02035 · Cited by 615
Metadata
- Authors
- Li, X., Robinson, S. M., Gupta, A., Saha, K., Jiang, Z., Moyano, D. F., Sahar, A., Riley, M. A., & Rotello, V. M.
- Venue
- ACS Nano
- Publisher
- American Chemical Society (ACS)
- Published
- 2014-09-22
- Volume
- 8
- Issue
- 10
- Pages
- 10682-10686
- ISSN
- 1936-0851 (ISSN-L)
- 1936-086X
- OpenAlex
- W2335063618
- Cited by
- 765
- References
- 7
- FWCI
- 20.70
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Li, X., Robinson, S. M., Gupta, A., Saha, K., Jiang, Z., Moyano, D. F., Sahar, A., Riley, M. A., & Rotello, V. M. (2014). Functional Gold Nanoparticles as Potent Antimicrobial Agents against Multi-Drug-Resistant Bacteria. ACS Nano. https://doi.org/10.1021/nn5042625
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
