Cited by 57Skin Protection and AgingSeaweed-derived Bioactive CompoundsProtease and Inhibitor Mechanisms

Effect of Costaria costata Fucoidan on Expression of Matrix Metalloproteinase-1 Promoter, mRNA, and Protein

Moon, Hee Jung, Park, Kyong Sik, Ku, Mi Jeong, Lee, Myeong Sook, Jeong, Seok Hoon, Imbs, Tatyana I., Zvyagintseva, Tatyana N., Ermakova, Svetlana P. +1 more·2009·Journal of Natural Products

Abstract

Fucoidans are sulfated fucosylated polymers from brown algae cell walls. We assessed the inhibitory effects of Costaria costata fucoidan on UVB-induced MMP-1 promoter, mRNA, and protein expression in vitro using the immortalized human keratinocyte (HaCaT) cell line. Pretreatment with fucoidan significantly inhibited MMP-1 protein expression compared to UVB irradiation alone. Fucoidan significantly reduced MMP-1 mRNA expression and inhibited UVB-induced MMP-1 promoter activity by 37.3%, 53.3%, and 58.5% at 0.01, 0.1, and 1 microg/mL, respectively, compared to UVB irradiation alone. C. costata fucoidan may be a potential therapeutic agent to prevent and treat skin photoaging.

Integrity signals

Registry

Crossref · 10.1021/np800797v

Cites

39 of 39 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Cites

Flagged first, then by citations

Cited by

Sorted by citations

Authors
Moon, H. J., Park, K. S., Ku, M. J., Lee, M. S., Jeong, S. H., Imbs, T. I., Zvyagintseva, T. N., Ermakova, S. P., & Lee, Y. H.
Affiliations
  • Yonsei University (KR)
  • Institute of Natural Products for Health Promotion and Department of Preventive Medicine, College of Medicine, Kosin University, Busan, 602-702, Korea, Department of Laboratory Medicine, College of Medicine, Yonsei University, Seoul, 120-749, Korea, and Pacific Institute of Bioorganic Chemistry of Far East Branch of the Russian Academy of Sciences, Vladivostok-22, Russian Federation
Corresponding author
Lee, Yong Hwan
Venue
Journal of Natural Products
Published
2009-10-06
Volume
72
Issue
10
Pages
1731-1734
ISSN
  • 0163-3864 (ISSN-L)
  • 1520-6025
OpenAlex
W2089696691
Cited by
57
References
39
Citations by year
2025: 1 · 2024: 5 · 2023: 3 · 2022: 2 · 2021: 3 · 2020: 5 · 2019: 8 · 2018: 4 · 2017: 3 · 2016: 2 · 2015: 4 · 2014: 3 · 2013: 2 · 2012: 5
FWCI
5.01
Type
journal article
Language
en
Open access
closed
Locations
  • Journal of Natural Products (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Dermatology › Skin Protection and Aging
  • Life Sciences › Agricultural and Biological Sciences › Aquatic Science › Seaweed-derived Bioactive Compounds
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Cancer Research › Protease and Inhibitor Mechanisms
Keywords
Costaria costata, fucoidan, MMP-1, UVB irradiation, photoaging, keratinocytes, brown algae polysaccharides, anti-aging agents
MeSH terms
Phaeophyceae, Cell Wall, Humans, Polysaccharides, Proteins, RNA, Messenger, Ultraviolet Rays, Skin Aging, Matrix Metalloproteinase 1

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review