Cited by 575Gastrointestinal motility and disordersPsychosomatic Disorders and Their TreatmentsGastrointestinal Bleeding Diagnosis and Treatment

The DOI matches its Crossref record; 23 of the 23 references it cites were found in a registry or an index.

Demography, Clinical Characteristics, Psychological and Abuse Profiles, Treatment, and Long-Term Follow-up of Patients with Gastroparesis

Soykan, Irfan, Sivri, Bulent, Sarosiek, Irene, Kiernan, Brian, Mccallum, Richard W.·1998·Digestive Diseases and Sciences

Abstract

Patients with gastroparesis frequently present challenging clinical, diagnostic, and therapeutic problems. Data from 146 gastroparesis patients seen over six years were analyzed. Patients were evaluated at the time of initial diagnosis and at the most recent follow-up in terms of gastric emptying and gastrointestinal symptomatology. The psychological status and physical and sexual abuse history in female idiopathic gastroparesis patients were ascertained and an association between those factors and gastrointestinal symptomatology was sought. Eighty-two percent of patients were females (mean age: 45 years old). The mean age for onset of gastroparesis was 33.7 years. The etiologies in 146 patients are: 36% idiopathic, 29% diabetic, 13% postgastric surgery, 7.5% Parkinson's disease, 4.8% collagen vascular disorders, 4.1% intestinal pseudoobstruction, and 6% miscellaneous causes. Subgroups were identified within the idiopathic group: 12 patients (23%) had a presentation consistent with a viral etiology, 48% had very prominent abdominal pain. Other subgroups were gastroesophageal reflux disease and nonulcer dyspepsia (19%), depression (23%), and onset of symptoms immediately after cholecystectomy (8%). Sixty-two percent of women with idiopathic gastroparesis reported a history of physical or sexual abuse, and physical abuse was significantly associated with abdominal pain, somatization, depression, and lifetime surgeries. At the end of the follow-up period, 74% required continuous…

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Crossref · 10.1023/a:1026665728213

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23 of 23 references verified0 citation errors · 0 not checkable

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  • In case series, estimated mortality rates in patients with gastroparesis range from 38% at 4 years to 34% at 25 years.

    “In case series, estimated mortality rates in patients with gastroparesis range from 38% at 4 years to 34% at 25 years (28–33).”

    From Diabetic Gastroparesis. (2019) · cites this paper as [29]

  • In diabetes, chronic hyperglycemia and reduced trophic factors, in particular the reduction of KIT/stem cell factor (SCF), cause the loss or dysfunction of ICCs, leading to dysregulated gastric emptying.

    “In diabetes, chronic hyperglycemia, and reduced trophic factors, in particular the reduction of KIT/stem cell factor (SCF), cause the loss or dysfunction of ICCs [52], leading to dysregulated gastric emptying [4, 19, 53].”
  • In diabetes, insulin and IGF-1 deficiency causes muscle atrophy and reduced SCF production, leading to ICC depletion and impaired neuromuscular transmission.

    “In diabetes, insulin and IGF-1 deficiency causes muscle atrophy and reduced SCF production, leading to ICC depletion and impaired neuromuscular transmission [52–60].”

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Research works printed but not linked: 5

  1. McCallum RW: Motor function of the stomach in health and disease. InGastrointestinal Disease—Pathophysiology, Diagnosis and Management. MH Sleisinger and JS Fordtran (eds). Philadelphia, WB Saunders Co., 1989, pp 675-713
  2. Butler RW, Satz P: Personality assessment of adults and children. InComprehensive Textbook of Psychiatry/VI. HI Kaplan, BJ Sadock (eds). Baltimore, Williams & Wilkins, 1995, pp 544-562
  3. Canadian National Survey, Committee on Sexual Offenses Against Children and Youth: Sexual Offenses Against Children. Ottawa, Canadian Government Publishing Centre, 1984
  4. Weber FH, McCallum RW: Gastric motor disorders. InConsultations in Gastroenterology. WJ Snape (ed). WB Saunders Co., Philadelphia, 1996, pp 247-259
  5. Valenzuela G, Weber FH, Nance W, McCallum RW: Waardenburg syndrome and gastricstasis in adults. Va Med Q 122:279-280, 1995

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Metadata

Authors
Soykan, I., Sivri, B., Sarosiek, I., Kiernan, B., & Mccallum, R. W.
Venue
Digestive Diseases and Sciences
Published
1998-11
Volume
43
Issue
11
Pages
2398-2404
ISSN
  • 0163-2116 (ISSN-L)
  • 1573-2568
OpenAlex
W1502294688
Cited by
575
References
23
Citations by year
2026: 11 · 2025: 18 · 2024: 15 · 2023: 24 · 2022: 24 · 2021: 24 · 2020: 42 · 2019: 36 · 2018: 21 · 2017: 26 · 2016: 26 · 2015: 30 · 2014: 20 · 2013: 31 · 2012: 28
FWCI
2.44
Type
journal article
Language
en
Open access
closed
Locations
  • Digestive Diseases and Sciences (publishedVersion)
  • PubMed (publishedVersion)
Funders
National Center for Research Resources (M01RR000847)
Topics
  • Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
  • Health Sciences › Medicine › Psychiatry and Mental health › Psychosomatic Disorders and Their Treatments
  • Health Sciences › Medicine › Gastroenterology › Gastrointestinal Bleeding Diagnosis and Treatment
Keywords
gastroparesis, idiopathic gastroparesis, gastric emptying, physical abuse, sexual abuse, depression, somatization, abdominal pain, prokinetic therapy, treatment response, long-term outcomes, Parkinson's disease, connective tissue diseases, viral etiology, gastroesophageal reflux disease, functional dyspepsia, cholecystectomy, gastric electrical stimulation
MeSH terms
Adolescent, Adult, Aged, Combined Modality Therapy, Demography, Disease Susceptibility, Female, Follow-Up Studies, Gastric Emptying, Humans, Male, Middle Aged, Psychometrics, Time Factors, Battered Women, Gastroparesis, Statistics, Nonparametric

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