Size-Dependent Bioadhesion of Micro- and Nanoparticulate Carriers to the Inflamed Colonic Mucosa

Hapten-Induced Model of Chronic Inflammation and Ulceration in the Rat Colon

Morris, G. P., Beck, P. L., Herridge, M. S., Depew, W. T., Szewczuk, M. R., & Wallace, J. L. (1989) · Gastroenterology · doi:10.1016/s0016-5085(89)80079-4 · Cited by 1,832 · see citing works

Quantitative assay for acute intestinal inflammation based on myeloperoxidase activity

Krawisz, J. E., Sharon, P., & Stenson, W. F. (1984) · Gastroenterology · doi:10.1016/0016-5085(84)90202-6 · Cited by 1,770 · see citing works

Experimental models of inflammatory bowel disease

Elson, C. O., Sartor, R. B., Tennyson, G. S., & Riddell, R. H. (1995) · Gastroenterology · doi:10.1016/0016-5085(95)90599-5 · Cited by 1,212 · see citing works

Gastrointestinal Uptake of Biodegradable Microparticles: Effect of Particle Size

Desai, M. P., Labhasetwar, V. D., Amidon, G. L., & Levy, R. J. (1996) · Pharmaceutical Research · doi:10.1023/a:1016085108889 · Cited by 941 · see citing works

Nanoparticle Uptake by the Rat Gastrointestinal Mucosa: Quantitation and Particle Size Dependency

Jani, P., Halbert, G. W., Langridge, J., & Florence, A. T. (1990) · Journal of Pharmacy and Pharmacology · doi:10.1111/j.2042-7158.1990.tb07033.x · Cited by 920 · see citing works

The Uptake and Translocation of Latex Nanospheres and Microspheres after Oral Administration to Rats

Jani, P. U., Halbert, G., Langridge, J., & Florence, A. T. (1989) · Journal of Pharmacy and Pharmacology · doi:10.1111/j.2042-7158.1989.tb06377.x · Cited by 394 · see citing works

Clinical Pharmacokinetics of Sulphasalazine, Its Metabolites and Other Prodrugs of 5-Aminosalicylic Acid

Klotz, U. E. (1985) · Clinical Pharmacokinetics · doi:10.2165/00003088-198510040-00001 · Cited by 280 · see citing works

Phagocytosis of polymer microspheres by macrophages

Tabata, Y., & Ikada, Y. (2006) · Springer eBooks · doi:10.1007/bfb0043062 · Cited by 271 · see citing works

A comparative analysis of two models of colitis in rats

Yamada, T., Marshall, S. J., Specian, R. D., & Grisham, M. B. (1992) · Gastroenterology · doi:10.1016/0016-5085(92)91710-l · Cited by 264 · see citing works

Colonic Drug Targeting

Kinget, R., Kalala, W., Vervoort, L., et al. (1998) · Journal of drug targeting · doi:10.3109/10611869808997888 · Cited by 194 · see citing works

Design of a new multiparticulate system for potential site-specific and controlled drug delivery to the colonic region

Rodrı́guez, M., Vila-Jato, J. L., & Torres, D. (1998) · Journal of Controlled Release · doi:10.1016/s0168-3659(98)00029-7 · Cited by 192 · see citing works

Size effect on systemic and mucosal immune responses induced by oral administration of biodegradable microspheres

Tabata, Y. (1996) · Vaccine · doi:10.1016/s0264-410x(96)00149-1 · Cited by 181 · see citing works

Mechanisms of action of sucralfate.

Nagashima, R. (1981) · PubMed · Cited by 180 · see citing works

Colonic Drug Delivery

Watts, P., & Lllum, L. (1997) · Drug Development and Industrial Pharmacy · doi:10.3109/03639049709148695 · Cited by 162 · see citing works

Disruption of intestinal barrier function associated with experimental colitis: possible role of mast cells

Stein, J. M., Ries, J., & Barrett, K. E. (1998) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.1998.274.1.g203 · Cited by 116 · see citing works

Macrophage heterogeneity in normal colonic mucosa and in inflammatory bowel disease.

Allison, M. C., Cornwall, S., Poulter, L. W., Dhillon, A. P., & Pounder, R. E. (1988) · Gut · doi:10.1136/gut.29.11.1531 · Cited by 106 · see citing works

Development of an Oral Drug Delivery System Targeting Immune-Regulating Cells in Experimental Inflammatory Bowel Disease: A New Therapeutic Strategy

Nakase, H., Okazaki, K., Tabata, Y., Uose, S., Ohana, M., Uchida, K., Matsushima, Y., Kawanami, C., Oshima, C., Ikada, Y., et al. (2000) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(24)35256-5 · Cited by 101 · see citing works

Glucocorticoid–Dextran Conjugates as Potential Prodrugs for Colon-Specific Delivery: Hydrolysis in Rat Gastrointestinal Tract Contents

McLeod, A. D., Friend, D. R., & Tozer, T. N. (1994) · Journal of Pharmaceutical Sciences · doi:10.1002/jps.2600830919 · Cited by 98 · see citing works

Mucoadhesion of polystyrene nanoparticles having surface hydrophilic polymeric chains in the gastrointestinal tract

Sakuma, S., Sudo, R., Suzuki, N., et al. (1999) · International Journal of Pharmaceutics · doi:10.1016/s0378-5173(98)00346-9 · Cited by 89 · see citing works

Dendritic cells and scavenger macrophages in chronic inflammatory bowel disease.

Seldenrijk, C. A., Drexhage, H. A., Meuwissen, S. G. M., et al. (1989) · Gut · doi:10.1136/gut.30.4.486 · Cited by 89 · see citing works

Persistent clonal expansions of peripheral blood CD4+ lymphocytes in chronic inflammatory bowel disease

Probert, C. S., Chott, A., Turner, J. R., Saubermann, L. J., Stevens, A. C., Bodinaku, K., Elson, C. O., Balk, S. P., & Blumberg, R. S. (1996) · The Journal of Immunology · doi:10.4049/jimmunol.157.7.3183 · Cited by 88 · see citing works

The transit rate of different-sized model dosage forms through the human colon and the effects of a lactulose-induced catharsis

Watts, P., Barrow, L., Steed, K., Wilson, C., Spiller, R., Melia, C. D., & Davies, M. (1992) · International Journal of Pharmaceutics · doi:10.1016/0378-5173(92)90245-w · Cited by 82 · see citing works

Medical therapy of ulcerative colitis

Hanauer, S. (1993) · The Lancet · doi:10.1016/0140-6736(93)92819-f · Cited by 78 · see citing works

Gastrointestinal transit of small tablets in patients with ulcerative colitis

Hardy, J., Davis, S., Khosla, R., & Robertson, C. (1988) · International Journal of Pharmaceutics · doi:10.1016/0378-5173(88)90249-9 · Cited by 56 · see citing works

Intracellular Visualization of Ampicillin-Loaded Nanoparticles in Peritoneal Macrophages Infected in Vitro with Salmonella typhimurium

Pinto-Alphandary, H., Balland, O., Laurent, M., Andremont, A., Puisieux, F., & Couvreur, P. (1994) · Pharmaceutical Research · doi:10.1023/a:1018985308984 · Cited by 53 · see citing works

Uptake of Nanoparticles by Rat Glomerular Mesangial Cells in Vivo and in Vitro

Manil, L., Davin, J., Duchenne, C., et al. (1994) · Pharmaceutical Research · doi:10.1023/a:1018993000633 · Cited by 50 · see citing works

The 21-aminosteroid tirilazad mesylate can ameliorate inflammatory bowel disease in rats.

Yue, G., Sun, F. F., Dunn, C., et al. (1996) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)12260-x · Cited by 40 · see citing works

Colonic delivery of dexamethasone from a prodrug accelerates healing of colitis in rats without adrenal suppression

Fedorak, R. N., Haeberlin, B., Empey, L. R., Cui, N., Nolen, H. W., Jewell, L. D., & Friend, D. R. (1995) · Gastroenterology · doi:10.1016/0016-5085(95)90130-2 · Cited by 37 · see citing works

Colon-specific Delivery of Budesonide with Azopolymer-coated Pellets: Therapeutic Effects of Budesonide with a Novel Dosage Form against 2,4,6-Trinitrobenzenesulphonic Acid-induced Colitis in Rats

Tozaki, H., Fujita, T., Komoike, J., et al. (1999) · Journal of Pharmacy and Pharmacology · doi:10.1211/0022357991772420 · Cited by 36 · see citing works

Migration of Adhesive and Nonadhesive Particles in the Rat Intestine under Altered Mucus Secretion Conditions

Tirosh, B., & Rubinstein, A. (1998) · Journal of Pharmaceutical Sciences · doi:10.1021/js9703380 · Cited by 30 · see citing works

Physical approaches to biomaterial design

Mitragotri, S., & Lahann, J. (2009) · Nature Materials · doi:10.1038/nmat2344 · Cited by 1,445 · see citing works

Nanoparticles as potential oral delivery systems of proteins and vaccines: A mechanistic approach

des Rieux, A., Fievez, V., Garinot, M., Schneider, Y.-J., & Préat, V. (2006) · Journal of Controlled Release · doi:10.1016/j.jconrel.2006.08.013 · Cited by 1,305 · see citing works

PLGA Nanoparticles for Oral Delivery of Hydrophobic Drugs: Influence of Organic Solvent on Nanoparticle Formation and Release Behavior In Vitro and In Vivo Using Estradiol as a Model Drug

Sahana, D. K., Mittal, G., Bhardwaj, V., & Kumar, M. N. V. R. (2008) · Journal of Pharmaceutical Sciences · doi:10.1002/jps.21158 · Cited by 260 · see citing works

Design of Estradiol Loaded PLGA Nanoparticulate Formulations: A Potential Oral Delivery System for Hormone Therapy

Hariharan, S., Bhardwaj, V., Bala, I., Sitterberg, J., Bakowsky, U., & Ravi Kumar, M. N. V. (2006) · Pharmaceutical Research · doi:10.1007/s11095-005-8418-y · Cited by 257 · see citing works

Advances in colon-targeted nano-drug delivery systems: challenges and solutions

Naeem, M., Awan, U. A., Subhan, F., Cao, J., Hlaing, S. P., Lee, J., Im, E., Jung, Y., & Yoo, J.-W. (2020) · Archives of Pharmacal Research · doi:10.1007/s12272-020-01219-0 · Cited by 248 · see citing works

Enteric coating of oral solid dosage forms as a tool to improve drug bioavailability

Maderuelo, C., Lanao, J. M., & Zarzuelo, A. (2019) · European Journal of Pharmaceutical Sciences · doi:10.1016/j.ejps.2019.105019 · Cited by 147 · see citing works

Intestinal organoids containing poly(lactic‐<i>co</i>‐glycolic acid) nanoparticles for the treatment of inflammatory bowel diseases

Davoudi, Z., Peroutka‐Bigus, N., Bellaire, B., Wannemuehler, M., Barrett, T. A., Narasimhan, B., & Wang, Q. (2018) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.36305 · Cited by 118 · see citing works

Use of lectin-functionalized particles for oral immunotherapy

Diesner, S. C., Wang, X.-Y., Jensen-Jarolim, E., Untersmayr, E., & Gabor, F. (2012) · Therapeutic Delivery · doi:10.4155/tde.11.146 · Cited by 40 · see citing works

Ultra-small solid archaeolipid nanoparticles for active targeting to macrophages of the inflamed mucosa

Higa, L. H., Jerez, H. E., de Farias, M. A., Portugal, R. V., Romero, E. L., & Morilla, M. J. (2017) · Nanomedicine · doi:10.2217/nnm-2016-0437 · Cited by 35 · see citing works

Three-dimensional Dammann confocal microscopy

Zhou, C. (2017) · Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE · doi:10.1117/12.2276581

The role of specimen‐induced spherical aberration in confocal microscopy

Török, P., Hewlett, S. J., & Varga, P. (1997) · Journal of Microscopy · doi:10.1046/j.1365-2818.1997.2440802.x · Cited by 61 · see citing works

Confocal theta microscopy and 4Pi-confocal theta microscopy

Lindek, S., & Stelzer, E. H. K. (1994) · Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE · doi:10.1117/12.172093 · Cited by 19 · see citing works

Confocal interference microscopy

Sheppard, C. J. R., & Zhou, H. (1997) · Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE · doi:10.1117/12.271254 · Cited by 3 · see citing works

Comparison of Endothelial Cell Count Using Confocal and Contact Specular Microscopy

Klais, C. M. C., Bühren, J., & Kohnen, T. (2003) · Ophthalmologica · doi:10.1159/000068562 · Cited by 59 · see citing works