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Glycoxidation and Diabetic Complications: Modern Lessons and a Warning?
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The amounts of AGEs in exogenous sources are usually much higher than those of endogenously produced AGEs.
“The amounts of AGEs in exogenous sources are usually much higher than those of endogenously produced AGEs2–4,24.”
From Advanced glycation end products (AGEs) and other adducts in aging-related diseases and alcohol-mediated tissue injury (2021) · cites this paper as [24]
Intake of foods and/or beverages with high levels of exogenous AGEs likely creates more health problems than endogenously produced AGEs.
“Thus, it is likely that the intake of foods and/or beverages with high levels of exogenous AGEs create more health problems than endogenously produced AGEs, although both exogenous and endogenous AGEs are similar in their biological functions and potentially act synergistically to stimulate oxidative stress, inflammation, and cellular damage, contributing to detrimental pathophysiology2–4,24.”
From Advanced glycation end products (AGEs) and other adducts in aging-related diseases and alcohol-mediated tissue injury (2021) · cites this paper as [24]
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Metadata
- Authors
- Vlassara, H., & Uribarri, J.
- Affiliations
- Icahn School of Medicine at Mount Sinai (US)
- Corresponding author
- Vlassara, Helen
- ORCID
- Uribarri, Jaime
- Venue
- Reviews in Endocrine and Metabolic Disorders
- Published
- 2004-08
- Volume
- 5
- Issue
- 3
- Pages
- 181-188
- ISSN
- 1389-9155 (ISSN-L)
- 1573-2606
- OpenAlex
- W2072265321
- Cited by
- 105
- References
- 59
- Citations by year
- 2026: 2 · 2025: 4 · 2024: 8 · 2023: 10 · 2022: 2 · 2021: 6 · 2020: 6 · 2019: 2 · 2018: 5 · 2017: 5 · 2016: 4 · 2015: 3 · 2014: 2 · 2013: 8 · 2012: 3
- FWCI
- 0.72
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- Locations
- Reviews in Endocrine and Metabolic Disorders (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Clinical Biochemistry › Advanced Glycation End Products research
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Aldose Reductase and Taurine
- Health Sciences › Medicine › Physiology (medical) › Nitric Oxide and Endothelin Effects
- Keywords
- glycoxidation, advanced glycation end products, diabetes complications, diabetes mellitus, oxidative stress
- MeSH terms
- Animals, Diabetes Mellitus, Glycolysis, Humans, Hyperglycemia, Glycation End Products, Advanced, Mice, Knockout, Oxidative Stress, Mice
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