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Cited by 17Autism Spectrum Disorder ResearchChild Nutrition and Feeding IssuesFamily and Disability Support Research

The DOI matches its Crossref record; 53 of the 54 references it cites were found in a registry or an index.

Self-reported social impairments predict depressive disorder in adults with autism spectrum disorder

Open access
Day, Talena C, McNaughton, Kathryn A, Naples, Adam J, McPartland, James C·2020·Autism
DOI 10.1177/1362361319857375PMC PMC6930361
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Abstract

In adults with autism spectrum disorder, co-occurring psychiatric conditions are prevalent, and depression is one of the most common co-occurring disorders. This study examined the relationship between depression and cognitive ability, autism symptom severity, and self-reported social impairments in autism spectrum disorder. A total of 33 adults with autism spectrum disorder and 28 adults with typical development completed a standardized psychiatric interview, cognitive test, measure of clinician-rated autism symptom severity, and self-report of social impairments. Nine participants with autism spectrum disorder (27%) met the criteria for a depressive disorder (autism spectrum disorder + depressive disorder). Relatively more females with autism spectrum disorder had a co-occurring depressive disorder. The typical development group had a higher intelligence quotient than the autism spectrum disorder group, but the autism spectrum disorder + depressive disorder group did not differ from the typical development or autism spectrum disorder group. While the autism spectrum disorder + depressive disorder group had lower clinician-rated autism symptom severity than the autism spectrum disorder group, the autism spectrum disorder + depressive disorder group reported more social impairments than the autism spectrum disorder group. Self-reported social impairments predicted depression in adults with autism spectrum disorder when accounting for symptom severity and cognitive ability. These findings suggest that more self-perceived social impairments are related to depressive disorders in autism spectrum disorder, and may help clinicians identify individuals who are vulnerable in developing a co-occurring depressive disorder. Future directions include follow-up studies with larger cohorts and longitudinal designs to support inferences regarding directionality of these relationships.

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Crossref · 10.1177/1362361319857375

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  • Client-related factors like irritability, lack of group identification, sensory sensitivity and avoidance, perceived lack of control, unemployment, isolation, executive dysfunctions, and genetic predispositions are associated with the development of comorbidities.

    “Client-related factors like irritability, lack of group identification, sensory sensitivity and avoidance, perceived lack of control over one's life, unemployment, isolation, executive dysfunctions, and genetic predispositions are also associated with the development of comorbidities (Day et al., 2020;Rossow et al., 2021).”

    From Rethinking psychological interventions in autism: Toward a neurodiversity‐affirming approach. (2025) · cites this paper as Day et al., 2020

    The Background lists genetic factors and social relationships as proposed risk factors for co-occurring depression in autism, and the Discussion links self-reported social impairments with depression in adults. The paper does not establish the other listed factors as risks for developing comorbidities generally; it also says longitudinal research is needed to determine the direction of the relationship. (LLM, conf=0.88)

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Cites

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1 of the 54 references couldn’t be matched to a known paper.

Research works printed but not linked: 5

  1. Brody D. J., 2018, NCHS Data Brief, 303, 1
  2. Constantino J. N., 2012, The Social Responsiveness Scale Manual, Second Edition (SRS-2)
  3. Lord C., 2012, Autism Diagnostic Observation Schedule– 2nd Edition (ADOS-2)
  4. Roy M., 2015, Psychiatria Danubina, 27, 50
  5. Wechsler D., 2011, Wechsler Abbreviated Scale of Intelligence–Second Edition (WASI-II)

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Metadata

Authors
Day, T. C., McNaughton, K. A., Naples, A. J., & McPartland, J. C.
Affiliations
Yale University (US)
Corresponding author
McPartland, James C
ORCID
Venue
Autism
Publisher
SAGE Publications
Published
2019-06-25
Volume
24
Issue
2
Pages
297-306
ISSN
  • 1362-3613 (ISSN-L)
  • 1461-7005
DOI
10.1177/1362361319857375
PMC
PMC6930361
OpenAlex
W2953542328
Cited by
17
References
54
Citations by year
2026: 2 · 2025: 5 · 2024: 2 · 2023: 1 · 2022: 3 · 2021: 3 · 2020: 1
FWCI
1.02
Type
journal article
Language
en
Open access
Licence
journals.sagepub.com/page/policies/text-and-data-mining-license (tdm)
Locations
  • Autism (publishedVersion)
  • PubMed (publishedVersion)
  • Europe PMC (PubMed Central) (acceptedVersion)
  • PubMed Central (acceptedVersion)
Funders
National Institute of Mental Health (R01 MH107426)
Topics
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
  • Health Sciences › Medicine › Psychiatry and Mental health › Child Nutrition and Feeding Issues
  • Social Sciences › Psychology › Clinical Psychology › Family and Disability Support Research
Keywords
autism spectrum disorder, depressive disorders, comorbid depression, social dysfunction, autism severity, cognitive ability, intelligence quotient, sex differences, autistic adults, psychiatric comorbidity
MeSH terms
Autism Spectrum Disorder, Adult, Connecticut, Depressive Disorder, Female, Humans, Male, Surveys and Questionnaires, Severity of Illness Index, Social Behavior, Comorbidity, Young Adult, Self Report

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