Cited by 484Substance Abuse Treatment and OutcomesPersonality Traits and PsychologyPersonality Disorders and Psychopathology

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Personality and substance use disorders: A prospective study.

Sher, Kenneth J., Bartholow, Bruce D., Wood, Mark D.·2000·Journal of Consulting and Clinical Psychology

DOI 10.1037/0022-006x.68.5.818

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Abstract

The personality systems of Cloninger (as measured by the Tridimensional Personality Questionnaire [TPQ]) and Eysenck (as measured by the Eysenck Personality Questionnaire [EPQ]) both have been linked to substance use and abuse. The current study examined the predictive utility of both systems for substance use disorder (SUD) diagnoses, both cross-sectionally and prospectively. Participants (N = 489 at baseline) completed the EPQ and TPQ and were assessed via structured diagnostic interview at baseline and 6 years later (N = 457 at follow-up). Both the EPQ and TPQ scales demonstrated bivariate cross-sectional and prospective associations with SUDs. Within each system, those dimensions marking a broad impulsive sensation-seeking or behavioral disinhibition trait were the best predictors prospectively, although the 2 systems were differentially sensitive to specific diagnoses. These relations remained significant even with autoregressivity, other concurrent SUD diagnoses, and multiple personality dimensions statistically controlled.

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Self-citation
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Self-citation
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Self-citation
Sex-Dependent Psychoneuroendocrine Effects of THC and MDMA in an Animal Model of Adolescent Drug Consumption
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The motivational basis of cognitive determinants of addictive behaviors
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Latent Trajectory Classes for Alcohol‐Related Blackouts from Age 15 to 19 in ALSPAC
Schuckit, M. A., Smith, T. L., Heron, J., Hickman, M., Macleod, J., Munafo, M. R., Kendler, K. S., Dick, D. M., & Smith, G. D. (2014) · Alcoholism Clinical and Experimental Research · doi:10.1111/acer.12601 · Cited by 42
“, impulsivity, sensation seeking, and a lack of conscientiousness) (Jennison and Johnson, 1994; Sher et al., 2000; Wetherill et al., 2012; White et al., 2002), and having friends who engage in heavy drinking and drug use (LaBrie et al.”
Background
A longitudinal study of personality traits, anxiety, and depressive disorders in young adults
Prince, E. J., Siegel, D. J., Carroll, C. P., Sher, K. J., & Bienvenu, O. J. (2021) · Anxiety, Stress, & Coping · doi:10.1080/10615806.2020.1845431 · Cited by 42
“The Eysenck Personality Questionnaire (EPQ) and the Diagnostic Interview Schedule (DIS) were administered over a 6-year period (Sher et al., 2000).”
BackgroundMethodSelf-citation
Assessing personality features and their relations with behavioral problems in adolescents: tridimensional personality questionnaire and junior eysenck personality questionnaire
Kuo, P., Chih, Y.-C., Soong, W., Yang, H., & Chen, W. J. (2003) · Comprehensive Psychiatry · doi:10.1016/j.comppsych.2003.09.011 · Cited by 42
Drinking Trajectories From Adolescence to the Fifties Among Alcohol-Dependent Men
Jacob, T., Koenig, L. B., Howell, D. N., Wood, P. K., & Haber, J. R. (2009) · Journal of Studies on Alcohol and Drugs · doi:10.15288/jsad.2009.70.859 · Cited by 42
Endocannabinoids and striatal function
Moreira, F. A., Jupp, B., Belin, D., & Dalley, J. W. (2014) · Behavioural Pharmacology · doi:10.1097/fbp.0000000000000109 · Cited by 44
“…that certain personality traits, including the seeking out of intense forms of sensation, novelty, and impulsivity may predispose to addiction (Sher et al., 2000; Adams et al., 2003; This is an open access article distributed under the Creative Commons Attribution License, which permits…”
Background
Borderline personality disorder in the context of self-regulation: Understanding symptoms and hallmark features as deficits in locomotion and assessment
Bornovalova, M. A., Fishman, S., Strong, D. R., Kruglanski, A. W., & Lejuez, C. W. (2007) · Personality and Individual Differences · doi:10.1016/j.paid.2007.07.001 · Cited by 40
Causal pathways between substance use disorders and personality pathology
Verheul, R., & van den Brink, W. (2005) · Australian Psychologist · doi:10.1080/00050060500094613 · Cited by 40
Animal Models of Drug Addiction
Belin‐Rauscent, A., & Belin, D. (2012) · InTech eBooks · doi:10.5772/52079 · Cited by 40
“Epidemiological studies in human populations have revealed striking associations between drug use [172-173b], and certain behavioural traits [174-189] such as anxiety [190-193], impulsivity [187;194-195] and sensation-seeking [176;183;196-199].”
Pleiotropic impact of constitutive fosB inactivation on nicotine-induced behavioral alterations and stress-related traits in mice
Zhu, H., Lee, M.-S., Agatsuma, S., & Hiroi, N. (2007) · Human Molecular Genetics · doi:10.1093/hmg/ddm027 · Cited by 39
Common and Distinct Associations Between Aggression and Alcohol Problems with Trait Disinhibition
Latzman, R. D., & Vaidya, J. G. (2012) · Journal of Psychopathology and Behavioral Assessment · doi:10.1007/s10862-012-9330-5 · Cited by 42
“…previous studies of aggression (e.g., Miller & Lynam 2001; Miller et al. 2008) and alcohol use/misuse (e.g., Hopwood et al. 2007; Ruiz et al. 2003; Sher et al. 2000), as noted earlier, comparisons of the size of associations confirmed low Agreeableness to be the strongest predictor of Proactive…”
Background
Associations Between the Big Five Personality Traits and the Non-Medical Use of Prescription Drugs for Cognitive Enhancement
Sattler, S., & Schunck, R. (2016) · Frontiers in Psychology · doi:10.3389/fpsyg.2015.01971 · Cited by 41
“…corroborate prior findings on a broad CE-measure (Middendorff et al., 2012) and other substances including prescription drugs, alcohol, nicotine, and illegal drugs (Sher et al., 2000; Malouff et al., 2007; Terracciano et al., 2008; Turiano et al., 2012; Benotsch et al., 2013; Lackner et al., 2013).”
BackgroundMethodResultInfluential
MAO‐B knockout mice exhibit deficient habituation of locomotor activity but normal nicotine intake
Lee, M., Chen, K., Shih, J. C., & Hiroi, N. (2004) · Genes Brain & Behavior · doi:10.1111/j.1601-1848.2004.00074.x · Cited by 37
“(Lipkus et al. 1994; Masse & Tremblay 1997; Sher et al. 2000).”
Background
Interacting personality traits? Smoking as a test case
Glicksohn, J., & Nahari, G. (2006) · European Journal of Personality · doi:10.1002/per.609 · Cited by 41
“This can be aligned with the work of Sher, Bartholow, and Wood (2000), who also reported finding no interactions among E, N and P in predicting substance use disorder.”
Background
Contextualizing individual differences in error monitoring: Links with impulsivity, negative affect, and conscientiousness
Hill, K. E., Samuel, D. B., & Foti, D. (2016) · Psychophysiology · doi:10.1111/psyp.12671 · Cited by 38
Do executive and reactive disinhibition mediate the effects of familial substance use disorders on adolescent externalizing outcomes?
Handley, E. D., Chassin, L., Haller, M. M., Bountress, K. E., Dandreaux, D. M., & Beltran, I. (2011) · Journal of Abnormal Psychology · doi:10.1037/a0024162 · Cited by 42
Alcoholics Anonymous and Reduced Impulsivity: A Novel Mechanism of Change
Blonigen, D. M., Timko, C., & Moos, R. H. (2013) · Substance Abuse · doi:10.1080/08897077.2012.691448 · Cited by 38
“In cross-sectional research, impulsivity is typically higher among individuals in AUD treatment than among those in the general population [7] and, in prospective studies, impulse control deficits tend to predate the onset of drinking problems [ 8 – 11 ].”
Background
The association between impulsivity and alcohol/drug use among prison inmates
Bernstein, M. H., McSheffrey, S., van den Berg, J. J., Vela, J. E., Stein, L. A. R., Roberts, M. B., Martin, R. A., & Clarke, J. G. (2014) · Addictive Behaviors · doi:10.1016/j.addbeh.2014.11.016 · Cited by 66
Personality Science in the Digital Age: The Promises and Challenges of Psychological Targeting for Personalized Behavior-Change Interventions at Scale
Matz, S., Beck, E. D., Atherton, O. E., White, M. J. D., Rauthmann, J. F., Mroczek, D. K., Kim, M.-H., & Bogg, T. (2023) · Perspectives on Psychological Science · doi:10.1177/17456916231191774 · Cited by 45
“…& Vedel Kessing, 2006), emergency medicine outcomes (e.g., Atherton, Willroth, et al., 2021; Chapman et al., 2011), general well-being (e.g., Abdullahi et al., 2020; Winzer et al., 2021), health behaviors (e.g., Bogg & Roberts, 2004), substance use and abuse (e.g., Sher et al., 2000), and more.”
Hopelessness, individualism, collectivism, and substance use among young rural-to-urban migrants in China
Du, H., Li, X., Lin, D., & Tam, C. C. (2014) · Health Psychology and Behavioral Medicine · doi:10.1080/21642850.2014.888656 · Cited by 41
“Moreover, personality traits related to disinhibition or behavioural undercontrol were associated with substance use disorders (Sher et al., 2000).”
Background
Different Phenotypic and Genotypic Presentations in Alcohol Dependence: Age at Onset Matters
Chen, Y.-C., Prescott, C. A., Walsh, D., Patterson, D. G., Riley, B. P., Kendler, K. S., & Kuo, P. (2011) · Journal of Studies on Alcohol and Drugs · doi:10.15288/jsad.2011.72.752 · Cited by 35
“, 1997); individuals with early onset of AD may exhibit more exploratory excitability, impulsiveness, and extravagance indicated by novelty seeking, and more anxiety, irritability, and changeable mood indicated by neuroticism (Sher et al., 2000).”
Background
Recent drinking consequences, motivation to change, and changes in alcohol consumption over a three month period
Blume, A. W., Schmaling, K. B., & Marlatt, G. A. (2005) · Addictive Behaviors · doi:10.1016/j.addbeh.2005.05.014 · Cited by 35
Personality Pathology and Substance Misuse in Later Life: Perspectives from Interviewer-, Self-, and Informant-Reports
Paul, S. E., Winograd, R., & Oltmanns, T. F. (2021) · Journal of Psychopathology and Behavioral Assessment · doi:10.1007/s10862-020-09862-z · Cited by 35
The association between drinking motives and alcohol‐related consequences – room for biases and measurement issues?
Gmel, G. E., Labhart, F., Fallu, J., & Kuntsche, E. N. (2012) · Addiction · doi:10.1111/j.1360-0443.2012.03892.x · Cited by 34
NrCAM ‐regulating neural systems and addiction‐related behaviors
Ishiguro, H., Hall, F. S., Horiuchi, Y., Sakurai, T., Hishimoto, A., Grumet, M., Uhl, G. R., Onaivi, E. S., & Arinami, T. (2012) · Addiction Biology · doi:10.1111/j.1369-1600.2012.00469.x · Cited by 34
A Preliminary Experimental Examination of the Effect of Emotion Dysregulation and Impulsivity on Risky Behaviors Among Women With Sexual Assault–Related Posttraumatic Stress Disorder
Weiss, N. H., Tull, M. T., & Gratz, K. L. (2014) · Behavior Modification · doi:10.1177/0145445514547957 · Cited by 35
Bulimic Behaviors and Alcohol Use: Shared Genetic Influences
Slane, J. D., Burt, S. A., & Klump, K. L. (2012) · Behavior Genetics · doi:10.1007/s10519-012-9525-2 · Cited by 33
“Importantly, impulsivity is associated with alcohol use disorders both cross-sectionally and prospectively (Sher et al. 2000) and predicts early initiation of alcohol (McGue et al.”
Background
Components of Disinhibition (Vs. Constraint) Differentially Predict Aggression and Alcohol Use
Latzman, R. D., Vaidya, J. G., Clark, L. A., & Watson, D. (2011) · European Journal of Personality · doi:10.1002/per.821 · Cited by 34
“…with regard to alcohol use are also consistent with hypotheses and extant literature (Hopwood et al., 2007; Martin & Sher, 1994; Ruiz et al., 2003; Sher et al., 2000) in that the primary DvC component associated with problematic alcohol use appears to be low Self-Control, with no contribution…”
Result
Personality Characterizations of Outpatients With Schizophrenia, Schizophrenia With Substance Abuse, and Primary Substance Abuse
Reno, R. M. (2004) · The Journal of Nervous and Mental Disease · doi:10.1097/01.nmd.0000142030.44203.63 · Cited by 33
“With regard to causality, both family and prospective studies have suggested links between neuroticism and extraversion and the onset of schizophrenia (DiLalla and Gottesman, 1995; Van Os and Jones, 2001) and between novelty-seeking/disinhibition/externalization and the development of substance misuse disorders (Sher…”
Background
A developmental perspective on personality and psychopathology across the life span
Wilson, S., & Olino, T. M. (2021) · Journal of Personality · doi:10.1111/jopy.12623 · Cited by 40
Disorders of Impulse Control
Sher, K. J., & Slutske, W. S. (2003) · Wiley eBooks · doi:10.1002/0471264385.wei0808 · Cited by 33
Self-citation
Validation de la traduction française de la SURPS pour une population d'adolescents québécois
Castonguay-Jolin, L., Perrier-Ménard, E., Ryan, N. C., Parent, S., Vitaro, F., Tremblay, R. E., Garel, P., Séguin, J. R., & Conrod, P. (2013) · The Canadian Journal of Psychiatry · doi:10.1177/070674371305800909 · Cited by 35
“ca 538 W La Revue canadienne de psychiatrie, vol 58, no 9, septembre 2013 CanJPsychiatry 2013;58(9):538–545”
Background
Psychometric Evaluation of the Substance Use Risk Profile Scale (SURPS) in an Inpatient Sample of Substance Users Using Cue-Reactivity Methodology
Schlauch, R. C., Crane, C. A., Houston, R. J., Molnar, D. S., Schlienz, N. J., & Lang, A. R. (2014) · Journal of Psychopathology and Behavioral Assessment · doi:10.1007/s10862-014-9462-x · Cited by 32
Polysubstance Use Among Minority Adolescent Males Incarcerated for Serious Offenses
Racz, S. J., Saha, S., Trent, M., Adger, H., Bradshaw, C. P., Goldweber, A., & Cauffman, E. E. (2015) · Child & Youth Care Forum · doi:10.1007/s10566-015-9334-x · Cited by 34
“Such behavioral difficulties, including impulsivity and behavioral disinhibition, have been consistently linked to substance use and substance use problems (Sher et al. 2000), as well as aggressive Child Youth Care Forum (2016) 45:205–220 207”
Combining Trait Models of Impulsivity to Improve Explanation of Substance Use Behaviour
Stautz, K., Dinc, L., & Cooper, A. J. (2017) · European Journal of Personality · doi:10.1002/per.2091 · Cited by 30
Personality Traits and Drinking Motives Predict Alcohol Misuse Among Canadian Aboriginal Youth
Mushquash, C. J., Stewart, S. H., Mushquash, A. R., Comeau, M. N., & McGrath, P. J. (2013) · International Journal of Mental Health and Addiction · doi:10.1007/s11469-013-9451-4 · Cited by 29
“Results converge with past research among majority culture youth (Sher et al. 2000), and indicate that individuals with a higher need to experience novel and intense Table 5 Hierarchical regression analysis predicting heavy episodic drinking and alcohol-related problems”
Result
Density of Familial Alcoholism and Its Effects on Alcohol Use and Problems in College Students
Capone, C., & Wood, M. D. (2008) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.2008.00716.x · Cited by 29
“…mediated by 3 previously identified etiological risk factors – age of onset of drinking , behavioral undercontrol, and current cigarette use – commensurate with previous research linking FHA with these constructs (Dawson, 2000; Hill and Yuan, 1999; Jackson et al., 2000; Sher et al., 1991, 2000).”
BackgroundSelf-citation
Drug Misuse and Diversion in Adults Prescribed Anxiolytics and Sedatives
McLarnon, M. E., Monaghan, T. L., Stewart, S. H., & Barrett, S. P. (2011) · Pharmacotherapy The Journal of Human Pharmacology and Drug Therapy · doi:10.1592/phco.31.3.262 · Cited by 29
“06 Alcohol dependence 14 (40) 6 (19) 3.”
The Primacy of Cognition in the Manifestations of Substance Use Disorders
Cadet, J. L., & Bisagno, V. (2013) · Frontiers in Neurology · doi:10.3389/fneur.2013.00189 · Cited by 29
Craving mediates the effect of impulsivity on lapse-risk during alcohol use disorder treatment
Coates, J. M., Gullo, M. J., Feeney, G. F. X., Young, R. M., Dingle, G. A., Clark, P. J., & Connor, J. P. (2020) · Addictive Behaviors · doi:10.1016/j.addbeh.2019.106286 · Cited by 29

Authors: Sher, K. J., Bartholow, B. D., & Wood, M. D.
Affiliations: University of Missouri (US)
ORCID: Sher, Kenneth J.
Bartholow, Bruce D.
Venue: Journal of Consulting and Clinical Psychology
Publisher: American Psychological Association (APA)
Published: 2000
Volume: 68
Issue: 5
Pages: 818-829
ISSN: 0022-006X (ISSN-L)
1939-2117
DOI: 10.1037/0022-006x.68.5.818
OpenAlex: W1991864809
Cited by: 483
References: 107
Citations by year: 2026: 4 · 2025: 5 · 2024: 7 · 2023: 15 · 2022: 12 · 2021: 9 · 2020: 35 · 2019: 12 · 2018: 21 · 2017: 11 · 2016: 27 · 2015: 18 · 2014: 26 · 2013: 34 · 2012: 33
FWCI: 5.10
Type: journal article
Language: en
Open access: closed
Locations: Journal of Consulting and Clinical Psychology (publishedVersion)
PubMed (publishedVersion)
Funders: National Institute on Alcohol Abuse and Alcoholism (R37 AA7231, P50AA011998, P50 AA 11998, R37AA007231)
Topics: Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
Social Sciences › Psychology › Clinical Psychology › Personality Traits and Psychology
Social Sciences › Psychology › Clinical Psychology › Personality Disorders and Psychopathology
Keywords: personality traits, substance use disorders, substance abuse, Eysenck Personality Questionnaire, Tridimensional Personality Questionnaire, impulsivity, sensation seeking, behavioral disinhibition, prospective prediction, autoregressive effects
MeSH terms: Adolescent, Adult, Cross-Sectional Studies, Female, Follow-Up Studies, Humans, Impulsive Behavior, Inhibition, Psychological, Male, Personality Disorders, Personality Inventory, Predictive Value of Tests, Prospective Studies, Risk-Taking, Sensitivity and Specificity, Logistic Models, Substance-Related Disorders

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Personality and substance use disorders: A prospective study.

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