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Comparative outcomes for individual cognitive-behavior therapy, supportive-expressive group psychotherapy, and sertraline for the treatment of depression in multiple sclerosis.
Abstract
This study compared the efficacy of 3 16-week treatments for depression in 63 patients with multiple sclerosis (MS) and major depressive disorder (MDD): individual cognitive-behavioral therapy (CBT), supportive-expressive group therapy (SEG). and the antidepressant sertraline. Significant reductions were seen from pre- to posttreatment in all measures of depression. Intent-to-treat and completers analyses using the Beck Depression Inventory (BDI; A. T. Beck, C. H. Ward. M. Medelson. J. Mock, & J. Erbaugh, 1961) and MDD diagnosis found that CBT and sertraline were more effective than SEG at reducing depression. These results were largely supported by the BDI-18, which eliminates BDI items confounded with MS. However, the Hamilton Rating Scale for Depression (M. Hamilton, 1960) did not show consistent differences between treatments. Reasons for this inconsistency are discussed. These findings suggest that CBT or sertraline is more likely to be effective in treating MDD in MS compared with supportive group treatments.
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“Controlled trials of behavioral interventions among patients with MS have focused upon treatment of depression, fatigue, or anxiety in patients selected for high symptom severity.16–18”
From MS quality of life, depression, and fatigue improve after mindfulness training: A randomized trial (2010) · cites this paper as [16]
Citations
Cites
Diagnostic and Statistical Manual of Mental Disorders
Williams, J. B. W., & First, M. B. (2013) · Oxford University Press eBooks · doi:10.1093/acrefore/9780199975839.013.104 · Cited by 109,845
An inventory for measuring depression
BECK, A. T. (1961) · Archives of General Psychiatry · doi:10.1001/archpsyc.1961.01710120031004 · Cited by 38,032
Hamilton, M. (1960) · Journal of Neurology, Neurosurgery & Psychiatry · doi:10.1136/jnnp.23.1.56 · Cited by 32,817
Rating neurologic impairment in multiple sclerosis: An expanded disability status scale (EDSS)
Kurtzke, J. F. (1983) · Neurology · doi:10.1212/wnl.33.11.1444 · Cited by 15,011
Littell, R. C. (1996) · Medical Entomology and Zoology · Cited by 10,345
Cognitive Therapy for Depression
(2012) · PsycEXTRA Dataset · doi:10.1037/e675542012-001 · Cited by 9,678
New diagnostic criteria for multiple sclerosis: Guidelines for research protocols
Poser, C. M., Paty, D. W., Scheinberg, L., McDonald, W. I., Davis, F. A., Ebers, G. C., Johnson, K. P., Sibley, W. A., Silberberg, D. H., & Tourtellotte, W. W. (1983) · Annals of Neurology · doi:10.1002/ana.410130302 · Cited by 7,384
A compendium of neuropsychological tests: administration, norms, and commentary
(1991) · Choice Reviews Online · doi:10.5860/choice.29-2400 · Cited by 6,118
A Compendium of Neuropsychological Tests: Administration, Norms, and Commentary
Levin, H. S. (1993) · Archives of Neurology · doi:10.1001/archneur.1993.00540050007005 · Cited by 4,796
Cognitive Therapy of Depression
HOLLON, S. D., & BECK, A. T. (1979) · Cognitive-Behavioral Interventions · doi:10.1016/b978-0-12-404480-7.50012-5 · Cited by 4,685
Defining the clinical course of multiple sclerosis
LUBLIN, F. D., & Reingold, S. C. (1996) · Neurology · doi:10.1212/wnl.46.4.907 · Cited by 3,762
Structured clinical interview for DSM-IV axis I disorders : SCID-I : clinical version : scoresheet
First, M. B., Spitzer, R. L., Gibbon, M., & Williams, J. B. W. (1997) · American Psychiatric Press eBooks · Cited by 3,101
Cognitive dysfunction in multiple sclerosis.
Rao, S. M., Leo, G. J., Bernardin, L., & Unverzagt, F. W. (1991) · Neurology · doi:10.1212/wnl.41.5.685 · Cited by 2,136
The theory and practice of group psychotherapy.
Gullickson, T., & Ramser, P. (1996) · Contemporary Psychology · doi:10.1037/002652 · Cited by 1,894
Keller, M. B. (1987) · Archives of General Psychiatry · doi:10.1001/archpsyc.1987.01800180050009 · Cited by 1,643
The Journal of Neuropsychiatry and Clinical Neurosciences
Bowden, V. M., & Bowden, C. (1992) · JAMA · doi:10.1001/jama.1992.03490110111047 · Cited by 1,106
Wampold, B. E., Mondin, G. W., Moody, M., Stich, F., Benson, K., & Ahn, H.-N. (1997) · Psychological Bulletin · doi:10.1037/0033-2909.122.3.203 · Cited by 1,091
Group Support for Patients With Metastatic Cancer: A Randomized Prospective Outcome Study
Spiegel, D. (1981) · Archives of General Psychiatry · doi:10.1001/archpsyc.1980.01780300039004 · Cited by 862
Jacobson, N. S., Roberts, L. J., Berns, S. B., & McGlinchey, J. B. (1999) · Journal of Consulting and Clinical Psychology · doi:10.1037/0022-006x.67.3.300 · Cited by 853
Jacobson, N. S., Roberts, L. J., Berns, S. B., & McGlinchey, J. B. (1999) · Journal of Consulting and Clinical Psychology · doi:10.1037//0022-006x.67.3.300 · Cited by 853
The theory and practice of group psychotherapy, 4th ed.
Yalom, I. D., & Leszcz, M. (1995) · Cited by 706
Boston Naming Test: shortened versions for use in Alzheimer's disease.
Mack, W., Freed, D., Williams, B. W., & Henderson, V. W. (1992) · Journal of Gerontology · doi:10.1093/geronj/47.3.p154 · Cited by 560
Normative comparisons for the evaluation of clinical significance.
Kendall, P. C., Marrs, A. L., Nath, S. R., & Sheldrick, R. C. (1999) · Journal of Consulting and Clinical Psychology · doi:10.1037//0022-006x.67.3.285 · Cited by 468
Hunkeler, E. M. (2000) · Archives of Family Medicine · doi:10.1001/archfami.9.8.700 · Cited by 464
Cause of death in patients attending multiple sclerosis clinics
Sadovnick, A. D., Eisen, K., Ebers, G. C., & Paty, D. W. (1991) · Neurology · doi:10.1212/wnl.41.8.1193 · Cited by 401
Mood Disorder and Multiple Sclerosis
Joffe, R. T., Lippert, G. P., Gray, T. A., Sawa, G. M., & Horvath, Z. (1987) · Archives of Neurology · doi:10.1001/archneur.1987.00520160018007 · Cited by 387
Koenig, H. G., George, L. K., Peterson, B. L., & Pieper, C. F. (1997) · American Journal of Psychiatry · doi:10.1176/ajp.154.10.1376 · Cited by 335
The Cognitive Therapy Scale: Psychometric properties.
Vallis, M., Shaw, B. F., & Dobson, K. S. (1986) · Journal of Consulting and Clinical Psychology · doi:10.1037//0022-006x.54.3.381 · Cited by 331
Treatment of Depression Improves Adherence to Interferon Beta-1b Therapy for Multiple Sclerosis
Mohr, D. C., Goodkin, D., Likosky, W., Gatto, N. M., Baumann, K. A., & Rudick, R. A. (1997) · Archives of Neurology · doi:10.1001/archneur.1997.00550170015009 · Cited by 306
Self-citationRevised estimate of the prevalence of multiple sclerosis in the united states
Anderson, D. W., Ellenberg, J. H., Leventhal, C. M., Reingold, S. C., Rodriguez, M., & Silberberg, D. H. (1992) · Annals of Neurology · doi:10.1002/ana.410310317 · Cited by 305
Depression in multiple sclerosis.
Minden, S., Orav, J., & Reich, P. (1987) · General Hospital Psychiatry · doi:10.1016/0163-8343(87)90052-1 · Cited by 267
Adjustment to multiple sclerosis: Application of a stress and coping model.
Pakenham, K. I. (1999) · Health Psychology · doi:10.1037//0278-6133.18.4.383 · Cited by 265
An Investigation into some Psychiatric Aspects of Multiple Sclerosis
Surridge, D. (1969) · The British Journal of Psychiatry · doi:10.1192/bjp.115.524.749 · Cited by 265
Mohr, D. C., Likosky, W., Bertagnolli, A., Goodkin, D. E., Wende, J. V. D., Dwyer, P., & Dick, L. P. (2000) · Journal of Consulting and Clinical Psychology · doi:10.1037//0022-006x.68.2.356 · Cited by 240
Self-citationGallagher-Thompson, D., & Steffen, A. M. (1994) · Journal of Consulting and Clinical Psychology · doi:10.1037/0022-006x.62.3.543 · Cited by 221
Depression as a major symptom of multiple sclerosis.
Whitlock, F. A., & Siskind, M. (1980) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.43.10.861 · Cited by 221
Mood Disorders and Dysfunction of the Hypothalamic-Pituitary-Adrenal Axis in Multiple Sclerosis
Fassbender, K. C., Schmidt, R., Mößner, R., Kischka, U., Kühnen, J., Schwartz, A., & Hennerici, M. G. (1998) · Archives of Neurology · doi:10.1001/archneur.55.1.66 · Cited by 204
Antidepressant pharmacotherapy of depression associated with multiple sclerosis
Schiffer, R. B., & WINEMAN, N. M. (1990) · American Journal of Psychiatry · doi:10.1176/ajp.147.11.1493 · Cited by 200
STRUCTURAL BRAIN CORRELATES OF EMOTIONAL DISORDER IN MULTIPLE SCLEROSIS
Rabins, P. V., Brooks, B. R., O'Donnell, P. V., Pearlson, G. D., Moberg, P. J., Jubelt, B., Coyle, P. K., Dalos, N. P., & Folstein, M. F. (1986) · Brain · doi:10.1093/brain/109.4.585 · Cited by 195
Disease activity and emotional state in multiple sclerosis
Dalos, N. P., Rabins, P. V., Brooks, B. R., & O'Donnell, P. V. (1983) · Annals of Neurology · doi:10.1002/ana.410130517 · Cited by 183
Correlation of neuropsychological and MRI findings in chronic/progressive multiple sclerosis
Franklin, G. M., Heaton, R. K., Nelson, L. M., Filley, C., & Seibert, C. (1988) · Neurology · doi:10.1212/wnl.38.12.1826 · Cited by 177
Multiple sclerosis: Empirical literature for the clinical health psychologist
Mohr, D. C., & Cox, D. (2001) · Journal of Clinical Psychology · doi:10.1002/jclp.1042 · Cited by 176
Self-citationWhat does the BDI measure in chronic pain?
Williams, A. C. D. C., & Richardson, P. H. (1993) · Pain · doi:10.1016/0304-3959(93)90155-i · Cited by 164
Lesions in the left arcuate fasciculus region and depressive symptoms in multiple sclerosis
Pujol, J., Bello, J., Deus, J., Martí-Vilalta, J. L., & Capdevila, A. (1997) · Neurology · doi:10.1212/wnl.49.4.1105 · Cited by 159
Treatment of depression in multiple sclerosis: Review and meta-analysis.
Mohr, D. C., & Goodkin, D. E. (1999) · Clinical Psychology: Science and Practice · doi:10.1093/clipsy.6.1.1 · Cited by 155
Self-citationIncreased Depression in Multiple Sclerosis Patients
Schubert, D. S. P., & Foliart, R. H. (1993) · Psychosomatics · doi:10.1016/s0033-3182(93)71902-7 · Cited by 151
New diagnostic criteria for multiple sclerosis
Petereit, H. F., & Heiss, W. (2002) · Annals of Neurology · doi:10.1002/ana.10152 · Cited by 140
Depressive episodes in patients with multiple sclerosis
Schiffer, R. B., Caine, E. D., Bamford, K. A., & Levy, S. (1983) · American Journal of Psychiatry · doi:10.1176/ajp.140.11.1498 · Cited by 137
Mohr, D. C., Goodkin, D. E., Likosk, W., Gatto, N., Neilley, L. K., Griffin, C., & Stiebling, B. (1996) · Multiple Sclerosis Journal · doi:10.1177/135245859600200502 · Cited by 131
Self-citationDepression, coping and level of neurological impairment in multiple sclerosis
Mohr, D. C., Goodkin, D. E., Gatto, N. M., & Wende, J. V. D. (1997) · Multiple Sclerosis Journal · doi:10.1177/135245859700300408 · Cited by 130
Self-citationIdentification of Beck Depression Inventory Items Related to Multiple Sclerosis
Mohr, D. C., Goodkin, D. E., Likosky, W., Beutler, L. E., Gatto, N. M., & Langan, M. K. (1997) · Journal of Behavioral Medicine · doi:10.1023/a:1025573315492 · Cited by 129
Self-citationDisability and depression in rheumatoid arthritis. A multi‐trait, multi‐method investigation
Peck, J. R., Smith, T. W., Ward, J. R., & Milano, R. (1989) · Arthritis & Rheumatism · doi:10.1002/anr.1780320908 · Cited by 128
Depression, cognitive impairment and social stress in multiple sclerosis
Gilchrist, A., & Creed, F. H. (1994) · Journal of Psychosomatic Research · doi:10.1016/0022-3999(94)90115-5 · Cited by 127
Aikens, J., Fischer, J., Namey, M., & Rudick, R. (2004) · Journal of behavioral medicine · doi:10.1023/a:1025547431847 · Cited by 125
An evaluation of cognitive-behaviour therapy for depression in patients with multiple sclerosis
Larcombe, N. A., & Wilson, P. H. (1984) · British Journal of Psychiatry · doi:10.1192/bjp.145.4.366 · Cited by 118
Prediction of psychological adjustment to multiple sclerosis
Barnwell, A. M., & Kavanagh, D. J. (1997) · Social Science & Medicine · doi:10.1016/s0277-9536(96)00356-5 · Cited by 116
Efficacy of stress-inoculation training in coping with multiple sclerosis.
Foley, F. W., Bedell, J. R., LaRocca, N. G., Scheinberg, L. C., & Reznikoff, M. (1987) · Journal of Consulting and Clinical Psychology · doi:10.1037/0022-006x.55.6.919 · Cited by 105
Symptom management in multiple sclerosis
Schapiro, R. T. (1994) · Annals of Neurology · doi:10.1002/ana.410360730 · Cited by 102
Beatty, W. W., & Monson, N. (1996) · Journal of the International Neuropsychological Society · doi:10.1017/s1355617700000989 · Cited by 96
Correlates of quality of life among persons with multiple sclerosis.
Gulick, E. (1997) · Nursing Research · doi:10.1097/00006199-199711000-00002 · Cited by 94
WINEMAN, N. M., Durand, E. J., & Steiner, R. P. (1994) · Research in Nursing & Health · doi:10.1002/nur.4770170306 · Cited by 84
The Role of Coping in Adjustment to Multiple Sclerosis-Related Adaptive Demands
Pakenham, K. I., Stewart, C. A., & Rogers, A. (1997) · Psychology, Health & Medicine · doi:10.1080/13548509708400578 · Cited by 81
Side effect profile and adherence to in the treatment of Multiple Sclerosis with interferon beta-la
Mohr, D. C., Likosky, W., Boudewyn, A. C., Marietta, P., Dwyer, P., Wende, J. V. D., & Goodkin, D. E. (1998) · Multiple Sclerosis Journal · doi:10.1177/135245859800400605 · Cited by 75
Self-citationOutcome Definitions and Predictors in Depression
Tedlow, J. R., D, M. F. M., Uebelacker, L. A., Nierenberg, A. A., Alpert, J. E., & Rosenbaum, J. F. (1998) · Psychotherapy and Psychosomatics · doi:10.1159/000012290 · Cited by 75
Correlates of depressed mood in ambulatory head and neck cancer patients
Kugaya, A., Akechi, T., Okamura, H., Mikami, I., & Uchitomi, Y. (1999) · Psycho-Oncology · doi:10.1002/(sici)1099-1611(199911/12)8:6 · Cited by 70
Course of Depression During the Initiation of Interferon Beta-1a Treatment for Multiple Sclerosis
Mohr, D. C., Likosky, W., Dwyer, P., Wende, J. V. D., Boudewyn, A. C., & Goodkin, D. (1999) · Archives of Neurology · doi:10.1001/archneur.56.10.1263 · Cited by 68
Self-citationDobkin, P. L., Costa, D. D., Joseph, L., Fortin, P. R., Edworthy, S. M., Barr, S. G., Ensworth, S., Esdaile, J. M., Beaulieu, A. D., Zummer, M., et al. (2002) · Annals of Behavioral Medicine · doi:10.1207/s15324796abm2402_05 · Cited by 63
Clinical Handbook of Health Psychology: A Practical Guide to Effective Interventions
Camic, P. M., & Knight, S. J. (2013) · Medical Entomology and Zoology · Cited by 62
(1985) · PubMed · Cited by 60
Principles of Medical Psychiatry
Malone, D. A. (1988) · Psychosomatics · doi:10.1016/s0033-3182(88)72355-5 · Cited by 59
Multiple sclerosis: Symptomatic treatment
Thompson, A. J. (1996) · Journal of Neurology · doi:10.1007/bf00900942 · Cited by 51
Whisman, M. A., Strosahl, K. D., Fruzzetti, A. E., Schmaling, K. B., Jacobson, N. S., & Miller, D. (1989) · Psychological Assessment · doi:10.1037/1040-3590.1.3.238 · Cited by 47
Stress Management for Multiple Sclerosis Patients
Crawford, J. D., & McIvor, G. P. (1987) · Psychological Reports · doi:10.2466/pr0.1987.61.2.423 · Cited by 44
The Natural History of Multiple Sclerosis
Goodkin, D. E. (1992) · Clinical medicine and the nervous system · doi:10.1007/978-1-4471-3184-7_2 · Cited by 40
Self-citationCharacterization of major depression symptoms in multiple sclerosis patients
Scott, T. F. M., Allen, D., Price, T. R., McConnell, H., & Lang, D. (1996) · Journal of Neuropsychiatry · doi:10.1176/jnp.8.3.318 · Cited by 40
Side effect profile and adherence to in the treatment of Multiple Sclerosis with interferon beta-1a
Mohr, D. C., Likosky, W., Boudewyn, A. C., Marietta, P., Dwyer, P., Wende, J. V. D., & Goodkin, D. E. (1998) · Multiple Sclerosis Journal · doi:10.1191/135245898678845160 · Cited by 38
Self-citationPsychotherapy for people with multiple sclerosis
Minden, S. L. (1992) · Journal of Neuropsychiatry · doi:10.1176/jnp.4.2.198 · Cited by 35
Treatment of Multiple Sclerosis: Trial Design, Results, and Future Perspectives
Rudick, R. A. (1992) · Cited by 35
The Theory and Practice of Group Psychotherapy:
Yalom, I. D., & Crouch, E. C. (1990) · British Journal of Psychiatry · doi:10.1192/s0007125000062723 · Cited by 32
Principles of Medical Psychiatry
Greenberg, D. B., & Fogel, B. S. (2015) · Oxford University Press eBooks · doi:10.1093/med/9780199731855.003.0001 · Cited by 32
The effects of imagery on attitudes and moods in multiple sclerosis patients.
Bl, M. (1996) · PubMed · Cited by 30
Current pharmacologic treatment of multiple sclerosis symptoms.
Andersson, P.-B., & Goodkin, D. E. (1996) · Europe PMC (PubMed Central) · Cited by 26
Self-citationGroup therapy for chronic medical illness: A multidiagnosis group
Stuber, M. L., Sullivan, G., Kennon, T. L., & Nobler, H. (1988) · General Hospital Psychiatry · doi:10.1016/0163-8343(88)90008-4 · Cited by 8
Research works printed but not linked: 11
- Classen, 1993, Brief supportive-expressive group therapy for women with primary breast cancer: A treatment manual.
- Cohen-Cole, 1987, Diagnostic assessment of depression in the medically ill., 23
- 10.1037/0022-006X.67.3.285 · DOI
- Mohr, 1998, Multiple sclerosis., 313
- 10.1093/clipsy/6.1.1 · DOI
- 10.1037/0022-006X.68.2.356 · DOI · Paper page
- 10.1037/0278-6133.18.4.383 · DOI
- Smith, 1982, Symbol Digit Modalities Test (SDMT) manual (revised).
- Spiegel, 2000, Group psychotherapy for cancer patients.
- 10.1037/0022-006X.54.3.381 · DOI · Paper page
- Wechsler, 1987, Wechsler Memory Scale--Revised manual.
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Siegert, R. J. (2005) · Journal of Neurology, Neurosurgery & Psychiatry · doi:10.1136/jnnp.2004.054635 · Cited by 718
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Metadata
- Authors
- Mohr, D. C., Boudewyn, A. C., Goodkin, D. E., Bostrom, A., & Epstein, L.
- Affiliations
- University of California, San Francisco (US)
- Kaiser Permanente (US)
- University of California Office of the President (US)
- ORCID
- Mohr, David C.
- Venue
- Journal of Consulting and Clinical Psychology
- Published
- 2001
- Volume
- 69
- Issue
- 6
- Pages
- 942-949
- ISSN
- 0022-006X (ISSN-L)
- 1939-2117
- OpenAlex
- W2028940268
- Cited by
- 334
- References
- 84
- Citations by year
- 2026: 7 · 2025: 4 · 2024: 4 · 2023: 9 · 2022: 2 · 2021: 9 · 2020: 11 · 2019: 11 · 2018: 8 · 2017: 24 · 2016: 19 · 2015: 20 · 2014: 13 · 2013: 24 · 2012: 23
- FWCI
- 13.49
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Consulting and Clinical Psychology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institute of Mental Health (R01-MH59708, R01MH059708)
- Topics
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Social Sciences › Psychology › Clinical Psychology › Psychotherapy Techniques and Applications
- Health Sciences › Medicine › Pharmacology (medical) › Treatment of Major Depression
- Keywords
- depression, multiple sclerosis, major depressive disorder, cognitive behavioral therapy, supportive-expressive group therapy, sertraline, antidepressant treatment, treatment efficacy comparison, Beck Depression Inventory, Hamilton Depression Rating Scale
- MeSH terms
- Major Depressive Disorder, Depressive Disorder, Major, Female, Humans, Male, Multiple Sclerosis, Psychotherapy, Group, Surveys and Questionnaires, Cognitive Behavioral Therapy, Selective Serotonin Reuptake Inhibitors, Sertraline
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