Cited by 130Neurotransmitter Receptor Influence on BehaviorNeural and Behavioral Psychology StudiesParkinson's Disease Mechanisms and Treatments

The effect of dopamine depletion from the caudate nucleus of the common marmoset (Callithrix jacchus) on tests of prefrontal cognitive function

Collins, P., Wilkinson, L. S., Everitt, B. J., Robbins, T. W., Roberts, A. C.·2000·Behavioral Neuroscience

Abstract

This study examined the effects of depletion of dopamine from the caudate nucleus of the common marmoset (Callithrix jacchus), on tasks sensitive to prefrontal damage (attentional set-shifting and spatial delayed response). There was a marked impairment in performance on the spatial delayed response task, but performance on the attentional set-shifting task was relatively preserved except for an impairment in re-engagement of a previously relevant perceptual dimension. This pattern of impairment is distinct from that seen after excitotoxic lesions of the prefrontal cortex and in patients with Parkinson's disease. Though it is not possible to identify specific cognitive functions that are independent of dopaminergic modulation of the caudate nucleus, due to the partial nature of the lesion, the results do provide insight into those cognitive processes that appear most dependent on caudate dopamine.

Integrity signals

Registry

Crossref · 10.1037/0735-7044.114.1.3

Cites

65 of 65 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Cites

Flagged first, then by citations

Cited by

Sorted by citations

Authors
Collins, P., Wilkinson, L. S., Everitt, B. J., Robbins, T. W., & Roberts, A. C.
Affiliations
University of Cambridge (GB)
Venue
Behavioral Neuroscience
Published
2000
Volume
114
Issue
1
Pages
3-17
ISSN
  • 0735-7044 (ISSN-L)
  • 1939-0084
OpenAlex
W2061471303
Cited by
129
References
64
Citations by year
2025: 2 · 2024: 4 · 2023: 7 · 2022: 2 · 2021: 3 · 2020: 2 · 2019: 3 · 2018: 2 · 2017: 3 · 2016: 3 · 2015: 5 · 2014: 7 · 2013: 5 · 2012: 4
FWCI
1.81
Type
journal article
Language
en
Open access
closed
Locations
  • Behavioral Neuroscience (publishedVersion)
  • PubMed (publishedVersion)
  • ORCA Online Research @Cardiff (Cardiff University) (submittedVersion)
Topics
  • Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
  • Health Sciences › Medicine › Neurology › Parkinson's Disease Mechanisms and Treatments
Keywords
dopamine depletion, caudate nucleus, Callithrix jacchus, set-shifting, dopaminergic modulation, prefrontal cortex, Parkinson's disease, nonhuman primate cognition
MeSH terms
Animals, Attention, Brain Mapping, Callithrix, Caudate Nucleus, Discrimination Learning, Dopamine, Field Dependence-Independence, Orientation, Parkinson Disease, Secondary, Pattern Recognition, Visual, Reaction Time, Mental Recall, Retention, Psychology, Reversal Learning, Oxidopamine, Prefrontal Cortex

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review