The effect of dopamine depletion from the caudate nucleus of the common marmoset (Callithrix jacchus) on tests of prefrontal cognitive function
Abstract
This study examined the effects of depletion of dopamine from the caudate nucleus of the common marmoset (Callithrix jacchus), on tasks sensitive to prefrontal damage (attentional set-shifting and spatial delayed response). There was a marked impairment in performance on the spatial delayed response task, but performance on the attentional set-shifting task was relatively preserved except for an impairment in re-engagement of a previously relevant perceptual dimension. This pattern of impairment is distinct from that seen after excitotoxic lesions of the prefrontal cortex and in patients with Parkinson's disease. Though it is not possible to identify specific cognitive functions that are independent of dopaminergic modulation of the caudate nucleus, due to the partial nature of the lesion, the results do provide insight into those cognitive processes that appear most dependent on caudate dopamine.
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Dopamine depletion in prefrontal cortex and striatum impairs cognitive control.
“and dopamine depletion in those brain areas impairs cognitive control (Clarke et al., 2011; Collins et al., 2000; Crofts et al., 2001; O'Neill and Brown, 2007).”
From Imaging addiction: D2 receptors and dopamine signaling in the striatum as biomarkers for impulsivity (2014) · cites this paper as Collins et al., 2000
Cites
Statistical Methods for Psychology.
Gudgeon, A. C., & Howell, D. C. (1994) · Journal of the Royal Statistical Society Series D (The Statistician) · doi:10.2307/2348956 · Cited by 8,277 · see citing works
Functional architecture of basal ganglia circuits: neural substrates of parallel processing
Alexander, G. E., & Crutcher, M. D. (1990) · Trends in Neurosciences · doi:10.1016/0166-2236(90)90107-l · Cited by 4,131 · see citing works
A Modified Card Sorting Test Sensitive to Frontal Lobe Defects
Nelson, H. E. (1976) · Cortex · doi:10.1016/s0010-9452(76)80035-4 · Cited by 2,454 · see citing works
Dissociation in prefrontal cortex of affective and attentional shifts
Dias, R., Robbins, T. W., & Roberts, A. C. (1996) · Nature · doi:10.1038/380069a0 · Cited by 1,527 · see citing works
Self-citationCognitive Deficit Caused by Regional Depletion of Dopamine in Prefrontal Cortex of Rhesus Monkey
Brozoski, T. J., Brown, R. M., Rosvold, H. E., & Goldman, P. S. (1979) · Science · doi:10.1126/science.112679 · Cited by 1,500 · see citing works
Context, cortex, and dopamine: A connectionist approach to behavior and biology in schizophrenia.
Cohen, J. D., & Servan‐Schreiber, D. (1992) · Psychological Review · doi:10.1037/0033-295x.99.1.45 · Cited by 1,494 · see citing works
Dopamine (3-hydroxytyramine) and brain function.
Hornykiewicz, O. (1966) · Pharmacological Reviews · doi:10.1016/s0031-6997(25)07154-6 · Cited by 1,389 · see citing works
Models of Information Processing in the Basal Ganglia
(1994) · doi:10.7551/mitpress/4708.001.0001 · Cited by 1,190 · see citing works
Mesocorticolimbic dopaminergic network: functional and regulatory roles
Moal, M. L., & Simon, H. (1991) · Physiological Reviews · doi:10.1152/physrev.1991.71.1.155 · Cited by 1,096 · see citing works
FRONTO-STRIATAL COGNITIVE DEFICITS AT DIFFERENT STAGES OF PARKINSON'S DISEASE
Owen, A. M., James-Galton, M., Leigh, P. N., Summers, B. A., MARSDEN, C. D., Quinn, N. P., Lange, K. W., & Robbins, T. W. (1992) · Brain · doi:10.1093/brain/115.6.1727 · Cited by 859 · see citing works
Self-citation(1964) · McGraw-Hill eBooks · Cited by 838 · see citing works
COGNITIVE DEFICITS IN THE EARLY STAGES OF PARKINSON'S DISEASE
Lees, A. J., & Smith, E. M. (1983) · Brain · doi:10.1093/brain/106.2.257 · Cited by 801 · see citing works
Scatton, B., Javoy-Agid, F., Rouquier, L., Dubois, B., & Agid, Y. (1983) · Brain Research · doi:10.1016/0006-8993(83)90993-9 · Cited by 727 · see citing works
Owen, A. M., Roberts, A. C., Polkey, C. E., Sahakian, B. J., & Robbins, T. W. (1991) · Neuropsychologia · doi:10.1016/0028-3932(91)90063-e · Cited by 657 · see citing works
Self-citationOwen, A. M., Roberts, A. C., Hodges, J. R., & Robbins, T. W. (1993) · Brain · doi:10.1093/brain/116.5.1159 · Cited by 639 · see citing works
Self-citationCooper, J. A., SAGAR, H. J., Jordan, N., Harvey, N. S., & Sullivan, E. V. (1991) · Brain · doi:10.1093/brain/114.5.2095 · Cited by 626 · see citing works
Lange, K. W., Robbins, T. W., MARSDEN, C. D., James-Galton, M., Owen, A. M., & Paul, G. M. (1992) · Psychopharmacology · doi:10.1007/bf02245167 · Cited by 608 · see citing works
Self-citationBehavioral effects of selective ablation of the caudate nucleus.
Divac, I., Rosvold, H. E., & Szwarcbart, M. K. (1967) · Journal of Comparative and Physiological Psychology · doi:10.1037/h0024348 · Cited by 568 · see citing works
Dias, R., Robbins, T. W., & Roberts, A. C. (1997) · The Journal of Neuroscience · doi:10.1523/jneurosci.17-23-09285.1997 · Cited by 555 · see citing works
Self-citationINTERNAL VERSUS EXTERNAL CUES AND THE CONTROL OF ATTENTION IN PARKINSON'S DISEASE
BROWN, R. G., & MARSDEN, C. D. (1988) · Brain · doi:10.1093/brain/111.2.323 · Cited by 552 · see citing works
Arnsten, A. F. T., & Goldman-Rakic, P. S. (1985) · Science · doi:10.1126/science.2999977 · Cited by 549 · see citing works
Downes, J. J., Roberts, A. C., Sahakian, B. J., Evenden, J. L., Morris, R. G., & Robbins, T. W. (1989) · Neuropsychologia · doi:10.1016/0028-3932(89)90128-0 · Cited by 527 · see citing works
Self-citationDias, R. S., Robbins, T. W., & Roberts, A. (1996) · Behavioral Neuroscience · doi:10.1037//0735-7044.110.5.872 · Cited by 476 · see citing works
Self-citationDias, R., Robbins, T. W., & Roberts, A. C. (1996) · Behavioral Neuroscience · doi:10.1037/0735-7044.110.5.872 · Cited by 476 · see citing works
Self-citationThe Frontal Cortex-Basal Ganglia System in Primates
Wise, S. P., Murray, E. A., & Gerfen, C. R. (1996) · Critical Reviews in Neurobiology · doi:10.1615/critrevneurobiol.v10.i3-4.30 · Cited by 437 · see citing works
Roberts, A., De Salvia, M., Wilkinson, L., Collins, P., Muir, J., Everitt, B., & Robbins, T. (1994) · The Journal of Neuroscience · doi:10.1523/jneurosci.14-05-02531.1994 · Cited by 415 · see citing works
Self-citationThe effect of Parkinson's disease on the ability to maintain a mental set.
Flowers, K. A., & Robertson, C. (1985) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.48.6.517 · Cited by 399 · see citing works
The Effect of Type and Area of Brain Lesion on Wisconsin Card Sorting Test Performance
Drewe, E. A. (1974) · Cortex · doi:10.1016/s0010-9452(74)80006-7 · Cited by 393 · see citing works
Arnsten, A., Cai, J., & Goldman-Rakic, P. (1988) · The Journal of Neuroscience · doi:10.1523/jneurosci.08-11-04287.1988 · Cited by 391 · see citing works
Cognitive and motor shifting aptitude disorder in Parkinson's disease.
Cools, A. R., van den Bercken, J. H., Horstink, M. W. I. M., van Spaendonck, K. P. M., & Berger, H. J. C. (1984) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.47.5.443 · Cited by 371 · see citing works
Roberts, A., Robbins, T. W., & Everitt, B. J. (1988) · PubMed · Cited by 306 · see citing works
Self-citationLevy, R., Friedman, H. R., Davachi, L., & Goldman-Rakic, P. S. (1997) · The Journal of Neuroscience · doi:10.1523/jneurosci.17-10-03870.1997 · Cited by 279 · see citing works
Neurobiology of Decision-Making
Damasio, A. R., Damasio, H., & Christen, Y. (1996) · Research and perspectives in neurosciences · doi:10.1007/978-3-642-79928-0 · Cited by 253 · see citing works
Chronic exposure to low doses of MPTP. I. Cognitive deficits in motor asymptomatic monkeys
Schneider, J. S., & Kovelowski, C. J. (1990) · Brain Research · doi:10.1016/0006-8993(90)90069-n · Cited by 246 · see citing works
Bättig, K., Rosvold, H. E., & Mishkin, M. (1960) · Journal of Comparative and Physiological Psychology · doi:10.1037/h0047392 · Cited by 236 · see citing works
Collins, P., Roberts, A., Dias, R. S., Everitt, B. J., & Robbins, T. W. (1998) · Journal of Cognitive Neuroscience · doi:10.1162/089892998562771 · Cited by 229 · see citing works
Self-citationBowen, F. P., KAMIENNY, R. S., Burns, M. M., & Yahr, M. D. (1975) · Neurology · doi:10.1212/wnl.25.8.701 · Cited by 219 · see citing works
Rosvold, H. E., & Delgado, J. M. R. (1956) · Journal of Comparative and Physiological Psychology · doi:10.1037/h0087991 · Cited by 177 · see citing works
Arnsten, A. F. T., & Contant, T. A. (1992) · Psychopharmacology · doi:10.1007/bf02245302 · Cited by 168 · see citing works
Reward-related Signals Carried by Dopamine Neurons
Schultz, W., Romo, R., Ljungberg, T., Mirenowicz, J., Hollerman, J. R., & Dickinson, A. (1994) · The MIT Press eBooks · doi:10.7551/mitpress/4708.003.0019 · Cited by 154 · see citing works
Mental dysfunction in Parkinson's disease
Wolters, E. C., & Francot, C. M. J. E. (1998) · Parkinsonism & Related Disorders · doi:10.1016/s1353-8020(98)00022-4 · Cited by 150 · see citing works
The Brain of the Common Marmoset (Callithrix Jacchus): A Stereotaxic Atlas
Stephan, H., Baron, G., & Schwerdtfeger, W. K. (1980) · Medical Entomology and Zoology · Cited by 142 · see citing works
Taylor, J. R., Elsworth, J. D., Roth, R. H., Sladek, J. R., & Redmond, D. E. (1990) · Brain · doi:10.1093/brain/113.3.617 · Cited by 140 · see citing works
Roberts, A., Robbins, T. W., Everitt, B. J., & Muir, J. L. (1992) · Neuroscience · doi:10.1016/0306-4522(92)90241-s · Cited by 139 · see citing works
Self-citationThe performance on learning tasks of patients in the early stages of Parkinson's disease
Canavan, A. G. M., Passingham, R. E., Marsden, C. D., Quinn, N., Wyke, M., & Polkey, C. E. (1989) · Neuropsychologia · doi:10.1016/0028-3932(89)90167-x · Cited by 133 · see citing works
The Brain of the Common Marmoset (Callithrix jacchus)
Stephan, H., Schwerdtfeger, W. K., & Baron, G. (1980) · Springer eBooks · doi:10.1007/978-3-642-67491-4 · Cited by 129 · see citing works
Rosvold, H. E., Mishkin, M. M., & Szwarcbart, M. K. (1958) · Journal of Comparative and Physiological Psychology · doi:10.1037/h0038337 · Cited by 127 · see citing works
A methodological analysis of shift paradigms in human discrimination learning.
Slamecka, N. J. (1968) · Psychological Bulletin · doi:10.1037/h0025762 · Cited by 125 · see citing works
Partiot, A., Vérin, M., Pillon, B., Teixeira-Ferreira, C., Agid, Y., & Dubois, B. (1996) · Neuropsychologia · doi:10.1016/0028-3932(95)00143-3 · Cited by 117 · see citing works
Context-dependent Activity in Primate Striatum Reflecting Past and Future Behavioral Events
Schultz, W., Apicella, P., Romo, R., & Scarnati, E. (1994) · The MIT Press eBooks · doi:10.7551/mitpress/4708.003.0005 · Cited by 113 · see citing works
Robinson, T. E., Mocsary, Z., Camp, D., & Whishaw, I. (1994) · Journal of Neuroscience · doi:10.1523/jneurosci.14-05-02687.1994 · Cited by 109 · see citing works
The Role of the Striatum in the Mental Chronometry of Action: A Theoretical Review
Robbins, T. W., & Brown, V. J. (1990) · Reviews in the Neurosciences · doi:10.1515/revneuro.1990.2.4.181 · Cited by 108 · see citing works
Self-citationSchneider, J. S., & Roeltgen, D. P. (1993) · Brain Research · doi:10.1016/0006-8993(93)90049-s · Cited by 102 · see citing works
Schneider, J. S. (1990) · Brain Research · doi:10.1016/0006-8993(90)90108-n · Cited by 99 · see citing works
How the Basal Ganglia Make Decisions
Berns, G. S., & B, T. J. S. A. (1996) · Research and perspectives in neurosciences · doi:10.1007/978-3-642-79928-0_6 · Cited by 95 · see citing works
Functions of the nervous system
Monnier, M. (1968) · Medical Entomology and Zoology · Cited by 94 · see citing works
Dopamine-mediated mechanisms of the prefrontal cortex
Goldman, P. S. (1992) · Seminars in Neuroscience · doi:10.1016/1044-5765(92)90013-r · Cited by 88 · see citing works
Comparison of the effects of frontal and caudate lesions on discrimination learning in monkeys.
Bättig, K., Rosvold, H. E., & Mishkin, M. (1962) · Journal of Comparative and Physiological Psychology · doi:10.1037/h0047328 · Cited by 80 · see citing works
Taylor, J. R., Roth, R. H., Sladek, J. R., & Redmond, D. E. (1990) · Behavioral Neuroscience · doi:10.1037//0735-7044.104.4.564 · Cited by 68 · see citing works
Taylor, J. R., Roth, R. H., Sladek, J. R., et al. (1990) · Behavioral Neuroscience · doi:10.1037/0735-7044.104.4.564 · Cited by 54 · see citing works
Delayed-response learning in the marmoset and the macaque.
Miles, R. C. (1957) · Journal of Comparative and Physiological Psychology · doi:10.1037/h0040257 · Cited by 45 · see citing works
Performance of squirrel monkeys on variants of delayed response.
French, G. M. (1959) · Journal of Comparative and Physiological Psychology · doi:10.1037/h0038973 · Cited by 34 · see citing works
The effects of bilateral striatal lesions on the acquisition of an operant test of short term memory
Döbrössy, M. D., Svendsen, C. N., & Dunnett, S. B. (1995) · Neuroreport · doi:10.1097/00001756-199510010-00023 · Cited by 19 · see citing works
Bilateral striatal lesions impair retention of an operant test of short-term memory
Döbrössy, M. D., Svendsen, C. N., & Dunnett, S. B. (1996) · Brain Research Bulletin · doi:10.1016/0361-9230(96)00160-8 · Cited by 18 · see citing works
A new perspective on firewalls
Schultz, E. (1995) · Network Security · doi:10.1016/1353-4858(96)89760-1 · Cited by 10 · see citing works
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Cools, R., & D'Esposito, M. (2011) · Biological Psychiatry · doi:10.1016/j.biopsych.2011.03.028 · Cited by 1,673 · see citing works
The cognitive functions of the caudate nucleus
Grahn, J. A., Parkinson, J. A., & Owen, A. M. (2008) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2008.09.004 · Cited by 942 · see citing works
Cools, R. (2001) · Cerebral Cortex · doi:10.1093/cercor/11.12.1136 · Cited by 906 · see citing works
Cools, R. (2006) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2005.03.024 · Cited by 903 · see citing works
Kehagia, A. A., Barker, R. A., & Robbins, T. W. (2010) · The Lancet Neurology · doi:10.1016/s1474-4422(10)70212-x · Cited by 883 · see citing works
Self-citationFunctional anatomy of thalamus and basal ganglia
Herrero, M.-T., Barcia, C., & Navarro, J. (2002) · Child s Nervous System · doi:10.1007/s00381-002-0604-1 · Cited by 660 · see citing works
Cognitive Impairment in Parkinson’s Disease: The Dual Syndrome Hypothesis
Kehagia, A. A., Barker, R. A., & Robbins, T. W. (2012) · Neurodegenerative Diseases · doi:10.1159/000341998 · Cited by 574 · see citing works
Self-citationTargeting the dopamine D1 receptor in schizophrenia: insights for cognitive dysfunction
Goldman-Rakic, P., Castner, S., Svensson, T., Siever, L., & Williams, G. (2004) · Psychopharmacology · doi:10.1007/s00213-004-1793-y · Cited by 544 · see citing works
Chudasama, Y., & Robbins, T. W. (2006) · Biological Psychology · doi:10.1016/j.biopsycho.2006.01.005 · Cited by 484 · see citing works
Self-citationFrank, M. J., & O'Reilly, R. C. (2006) · Behavioral Neuroscience · doi:10.1037/0735-7044.120.3.497 · Cited by 472 · see citing works
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Williams, G. V., & Castner, S. A. (2006) · Neuroscience · doi:10.1016/j.neuroscience.2005.09.028 · Cited by 326 · see citing works
Lewis, S. J. G., Słabosz, A., Robbins, T. W., Barker, R. A., & Owen, A. M. (2004) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2004.10.001 · Cited by 306 · see citing works
Self-citationLukowski, A. F., Koss, M., Burden, M. J., Jonides, J. J., Nelson, C. A., Kaciroti, N., Jiménez, E., & Lozoff, B. (2010) · Nutritional Neuroscience · doi:10.1179/147683010x12611460763689 · Cited by 303 · see citing works
Goschke, T., & Bolte, A. (2014) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2014.07.015 · Cited by 298 · see citing works
Crofts, H. S. (2001) · Cerebral Cortex · doi:10.1093/cercor/11.11.1015 · Cited by 284 · see citing works
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Morris, L. S., Kundu, P., Dowell, N., Mechelmans, D. J., Favre, P., Irvine, M. A., Robbins, T. W., Daw, N., Bullmore, E. T., Harrison, N. A., et al. (2016) · Cortex · doi:10.1016/j.cortex.2015.11.004 · Cited by 198 · see citing works
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Lee, B., Groman, S., London, E. D., & Jentsch, J. D. (2007) · Neuropsychopharmacology · doi:10.1038/sj.npp.1301337 · Cited by 148 · see citing works
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Nevalainen, N., Riklund, K., Andersson, M., Axelsson, J., Ögren, M., Lövdén, M., Lindenberger, U., Bäckman, L., & Nyberg, L. H. (2014) · Brain Research · doi:10.1016/j.brainres.2014.09.010 · Cited by 96 · see citing works
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Ragozzino, M. E. (2003) · Neurobiology of Learning and Memory · doi:10.1016/s1074-7427(03)00077-7 · Cited by 93 · see citing works
Dopaminergic Enhancement of Cognitive Function
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Leonibus, E. D., Pascucci, T., Lopez, S., Oliverio, A., Amalric, M., & Mele, A. (2007) · Psychopharmacology · doi:10.1007/s00213-007-0862-4 · Cited by 85 · see citing works
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Cools, R., Rogers, R. D., Barker, R. A., & Robbins, T. W. (2009) · Journal of Cognitive Neuroscience · doi:10.1162/jocn.2009.21227 · Cited by 84 · see citing works
Self-citationReeves, S., Grasby, P. M., Howard, R. J., Bantick, R. A., Asselin, M., & Mehta, M. A. (2005) · NeuroImage · doi:10.1016/j.neuroimage.2005.05.034 · Cited by 81 · see citing works
Grow, D. A., McCarrey, J. R., & Navara, C. S. (2016) · Stem Cell Research · doi:10.1016/j.scr.2016.08.013 · Cited by 80 · see citing works
Barlow, R. L., Alsiö, J., Jupp, B., Rabinovich, R., Shrestha, S., Roberts, A. C., Robbins, T. W., & Dalley, J. W. (2015) · Neuropsychopharmacology · doi:10.1038/npp.2014.335 · Cited by 77 · see citing works
Self-citationSubcortical intelligence: Caudate volume predicts IQ in healthy adults
Grazioplene, R. G., Ryman, S. G., Gray, J. R., Rustichini, A., Jung, R. E., & DeYoung, C. G. (2014) · Human Brain Mapping · doi:10.1002/hbm.22710 · Cited by 66 · see citing works
Castner, S. A., Vosler, P. S., & Goldman‐Rakic, P. S. (2005) · Biological Psychiatry · doi:10.1016/j.biopsych.2004.12.019 · Cited by 66 · see citing works
Mehta, M. A. (2003) · NeuroImage · doi:10.1016/j.neuroimage.2003.08.007 · Cited by 60 · see citing works
Mehta, M. A., Gumaste, D., Montgomery, A. J., McTavish, S. F. B., & Grasby, P. M. (2005) · Psychopharmacology · doi:10.1007/s00213-004-2128-8 · Cited by 58 · see citing works
Slaght, S., Paz, J. T., Mahon, S., Maurice, N., Charpier, S., & Deniau, J. (2002) · Epileptic Disorders · doi:10.1684/j.1950-6945.2002.tb00542.x · Cited by 57 · see citing works
Rule-based category learning in patients with Parkinson's disease
Price, A. L., Filoteo, J. V., & Maddox, W. T. (2009) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2009.01.031 · Cited by 54 · see citing works
Attention and visual dysfunction in Parkinson's disease
Botha, H., & Carr, J. A. (2012) · Parkinsonism & Related Disorders · doi:10.1016/j.parkreldis.2012.03.004 · Cited by 50 · see citing works
Li, Z., Chen, X., Wang, T., Gao, Y., Li, F. Y., Chen, L., Xue, J., He, Y., Li, Y., Guo, W. M., et al. (2017) · Biological Psychiatry · doi:10.1016/j.biopsych.2017.07.017 · Cited by 49 · see citing works
Langley, C., Gregory, S., Osborne‐Crowley, K., O’Callaghan, C., Zeun, P., Lowe, J., Johnson, E. B., Papoutsi, M., Scahill, R. I., Rees, G. E., et al. (2020) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp-2020-324104 · Cited by 49 · see citing works
Self-citationKarakuyu, D., Herold, C., Güntürkün, O., & Diekamp, B. (2007) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2007.05840.x · Cited by 47 · see citing works
Geddert, R., & Egner, T. (2022) · Journal of Experimental Psychology General · doi:10.1037/xge0001241 · Cited by 46 · see citing works
Dopamine asymmetry interacts with medication to affect cognition in Parkinson's disease
Tomer, R., Aharon‐Peretz, J., & Tsitrinbaum, Z. (2006) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2006.06.014 · Cited by 43 · see citing works
da Costa, A. L. C., Peppe, A., Mazzù, I. D., Longarzo, M., Caltagirone, C., & Carlesimo, G. A. (2014) · Behavioural Neurology · doi:10.1155/2014/260896 · Cited by 41 · see citing works
Cognitive control and the dopamine D2-like receptor: a dimensional understanding of addiction
Groman, S. M., & Jentsch, J. D. (2011) · Depression and Anxiety · doi:10.1002/da.20897 · Cited by 41 · see citing works
Marié, R., & Defer, G. (2003) · Current Opinion in Neurology · doi:10.1097/00019052-200312002-00006 · Cited by 39 · see citing works
Reward Acts on the pFC to Enhance Distractor Resistance of Working Memory Representations
Fallon, S. J., & Cools, R. (2014) · Journal of Cognitive Neuroscience · doi:10.1162/jocn_a_00676 · Cited by 38 · see citing works
Dopamine neurons gate the intersection of cocaine use, decision making, and impulsivity
Hynes, T. J., Hrelja, K. M., Hathaway, B. A., Hounjet, C. D., Chernoff, C. S., Ebsary, S. A., Betts, G. D., Russell, B., Ma, L., Kaur, S., et al. (2021) · Addiction Biology · doi:10.1111/adb.13022 · Cited by 38 · see citing works
Dopaminergic modulation of distracter-resistance and prefrontal delay period signal
Bloemendaal, M., van Schouwenburg, M. R., Miyakawa, A., Aarts, E., D’Esposito, M., & Cools, R. (2014) · Psychopharmacology · doi:10.1007/s00213-014-3741-9 · Cited by 37 · see citing works
Ko, J. H., Monchi, O., Ptito, A., Petrides, M., & Strafella, A. P. (2008) · International Journal of Biomedical Imaging · doi:10.1155/2008/143238 · Cited by 37 · see citing works
Cognitive and motor effects of dopaminergic medication withdrawal in Parkinson’s disease
Fern‐Pollak, L., Whone, A. L., Brooks, D. J., & Mehta, M. A. (2004) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2004.05.004 · Cited by 37 · see citing works
Sex differences in cognitive aging: a 4-year longitudinal study in marmosets
Rothwell, E. S., Workman, K. P., Wang, D., & Agnès Lacreuse, A. (2021) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2021.09.015 · Cited by 36 · see citing works
Oestradiol Modulation of Cognition in Adult Female Marmosets (Callithrix jacchus)
Agnès Lacreuse, A., Chang, J., Metevier, C. M., LaClair, M., Meyer, J. S., & Ferris, C. (2014) · Journal of Neuroendocrinology · doi:10.1111/jne.12147 · Cited by 33 · see citing works
Monetta, L., Grindrod, C. M., & Pell, M. D. (2007) · Journal of Neurolinguistics · doi:10.1016/j.jneuroling.2007.11.002 · Cited by 32 · see citing works
Ceaser, A. E., & Barch, D. M. (2016) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2015.00687 · Cited by 30 · see citing works
Pérez, V., Marı́n, C., Rubio, A., Aguilar, E., Barbanoj, M. J., & Kulisevsky, J. (2009) · Journal of Neural Transmission · doi:10.1007/s00702-009-0291-0 · Cited by 28 · see citing works
Moustafa, A. A., Bell, P. T., Eissa, A. M., & Hewedi, D. H. (2013) · Brain and Cognition · doi:10.1016/j.bandc.2013.04.001 · Cited by 27 · see citing works
The Schizophrenia Spectrum Personality Disorders
Chemerinski, E., & Siever, L. J. (2010) · Wiley eBooks · doi:10.1002/9781444327298.ch5 · Cited by 27 · see citing works
van den Bosch, R., Hezemans, F. H., Määttä, J. I., Hofmans, L., Papadopetraki, D., Verkes, R., Marquand, A. F., Booij, J., & Cools, R. (2023) · eLife · doi:10.7554/elife.83161 · Cited by 26 · see citing works
Calaminus, C., & Hauber, W. (2008) · Neuroscience · doi:10.1016/j.neuroscience.2008.04.046 · Cited by 26 · see citing works
Cognitive slowing in Parkinson's disease resolves after practice
Press, D. Z. (2002) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.73.5.524 · Cited by 26 · see citing works
Covariance‐based subdivision of the human striatum using T1‐weighted MRI
Cohen, M. X., Lombardo, M. V., & Blumenfeld, R. S. (2008) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2008.06117.x · Cited by 25 · see citing works
Gruszka, A., Hampshire, A., Barker, R. A., & Owen, A. M. (2017) · Cortex · doi:10.1016/j.cortex.2017.05.020 · Cited by 25 · see citing works
Chu, J., Liu, T., Wang, K., Han, C., Liu, Y.-P., Michitomo, S., Zhang, J., Fang, T., & Meng, F. (2018) · Aging and Disease · doi:10.14336/ad.2018.0814 · Cited by 24 · see citing works
Neuropsychopharmacology of Cognitive Flexibility
Cools, R. (2015) · Elsevier eBooks · doi:10.1016/b978-0-12-397025-1.00253-0 · Cited by 23 · see citing works
Fang, X., Sugiyama, K., Akamine, S., & Namba, H. (2006) · Neuroscience Research · doi:10.1016/j.neures.2006.04.010 · Cited by 23 · see citing works
Moustafa, A. A., & Maida, A. S. (2007) · Cognitive Systems Research · doi:10.1016/j.cogsys.2007.02.001 · Cited by 23 · see citing works
Bonnavion, P., Fernández, E. P., Varin, C., & d’Exaerde, A. D. K. (2019) · Neurochemistry International · doi:10.1016/j.neuint.2019.01.009 · Cited by 15 · see citing works
Robbins, T. W. (2009) · Oxford University Press eBooks · doi:10.1093/acprof:oso/9780195373035.003.0014 · Cited by 15 · see citing works
Self-citationAxelsson, S. F. A., Horst, N. K., Horiguchi, N., Roberts, A., & Robbins, T. W. (2021) · Journal of Neuroscience · doi:10.1523/jneurosci.0227-21.2021 · Cited by 13 · see citing works
Self-citationContrast Sensitivity in Children With and Without Attention Deficit Hyperactivity Disorder Symptoms
Bartgis, J., Lefler, E. K., Hartung, C. M., & Thomas, D. (2009) · Developmental Neuropsychology · doi:10.1080/87565640902964474 · Cited by 13 · see citing works
Aberrant Dopamine Transmission and Cognitive Dysfunction in Animal Models of Parkinson's Disease
Lelos, M. J., & Dunnett, S. B. (2011) · Journal of Parkinson s Disease · doi:10.3233/jpd-2011-11036 · Cited by 12 · see citing works
Pezze, M. A., Marshall, H. J., & Cassaday, H. J. (2015) · Psychopharmacology · doi:10.1007/s00213-015-3903-4 · Cited by 10 · see citing works
Dopamine — Its Role in Behaviour and Cognition in Experimental Animals and Humans
Robbins, T. W., & Everitt, B. J. (2002) · Handbook of experimental pharmacology · doi:10.1007/978-3-662-06765-9_7 · Cited by 10 · see citing works
Self-citationContextual control demands determine whether stability and flexibility trade off against each other
Geddert, R., & Egner, T. (2024) · Attention Perception & Psychophysics · doi:10.3758/s13414-024-02955-x · Cited by 7 · see citing works
Luque-Moreno, C., López, J. C., & Argandoña, E. D. (2012) · Revista de Neurología · doi:10.33588/rn.5505.2012261 · Cited by 6 · see citing works
Gestational and postnatal age associations for striatal tissue iron deposition in early infancy
Cabral, L. M., Calabro, F. J., Rasmussen, J. M., Foran, W., Moore, L. A., Graham, A. M., O’Connor, T. G., Wadhwa, P. D., Entringer, S., Fair, D. A., et al. (2023) · Developmental Cognitive Neuroscience · doi:10.1016/j.dcn.2023.101286 · Cited by 6 · see citing works
Witte, L. D., Engelborghs, S., Verhoeven, J., Deyn, P. P. D., & Mariën, P. (2008) · Behavioural Neurology · doi:10.1155/2008/693671 · Cited by 6 · see citing works
Zlatkina, V., Frey, S., & Petrides, M. (2024) · Cerebral Cortex · doi:10.1093/cercor/bhae444 · Cited by 5 · see citing works
- Authors
- Collins, P., Wilkinson, L. S., Everitt, B. J., Robbins, T. W., & Roberts, A. C.
- Affiliations
- University of Cambridge (GB)
- Venue
- Behavioral Neuroscience
- Published
- 2000
- Volume
- 114
- Issue
- 1
- Pages
- 3-17
- ISSN
- 0735-7044 (ISSN-L)
- 1939-0084
- OpenAlex
- W2061471303
- Cited by
- 129
- References
- 64
- Citations by year
- 2025: 2 · 2024: 4 · 2023: 7 · 2022: 2 · 2021: 3 · 2020: 2 · 2019: 3 · 2018: 2 · 2017: 3 · 2016: 3 · 2015: 5 · 2014: 7 · 2013: 5 · 2012: 4
- FWCI
- 1.81
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Behavioral Neuroscience (publishedVersion)
- PubMed (publishedVersion)
- ORCA Online Research @Cardiff (Cardiff University) (submittedVersion)
- Topics
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
- Health Sciences › Medicine › Neurology › Parkinson's Disease Mechanisms and Treatments
- Keywords
- dopamine depletion, caudate nucleus, Callithrix jacchus, set-shifting, dopaminergic modulation, prefrontal cortex, Parkinson's disease, nonhuman primate cognition
- MeSH terms
- Animals, Attention, Brain Mapping, Callithrix, Caudate Nucleus, Discrimination Learning, Dopamine, Field Dependence-Independence, Orientation, Parkinson Disease, Secondary, Pattern Recognition, Visual, Reaction Time, Mental Recall, Retention, Psychology, Reversal Learning, Oxidopamine, Prefrontal Cortex
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