Central blockade of muscarinic cholinergic receptors disrupts affective and attentional set‐shifting

Chen, Katy C.; Baxter, Mark G.; Rodefer, Joshua S.

doi:10.1111/j.1460-9568.2004.03548.x

Cited by 97Neurotransmitter Receptor Influence on BehaviorNeural and Behavioral Psychology StudiesNeuroscience and Neuropharmacology Research

The DOI matches its Crossref record; 55 of the 55 references it cites were found in a registry or an index.

Central blockade of muscarinic cholinergic receptors disrupts affective and attentional set‐shifting

Chen, Katy C., Baxter, Mark G., Rodefer, Joshua S.·2004·European Journal of Neuroscience

DOI 10.1111/j.1460-9568.2004.03548.x

Open this paper in CoChat — free account

Abstract

Impairments in multiple aspects of attentional and executive function follow damage to cholinergic neurons in the central nervous system. Affective and attentional set‐shifting represent two aspects of executive function controlled by different sectors of the prefrontal cortex. The involvement of cholinergic neural mechanisms in these aspects of executive function has not been specified. To determine whether central muscarinic cholinergic receptors were involved in affective and/or attentional set‐shifting, we tested rats on a series of discrimination learning problems, which included affective (reversal learning) and attentional set (extradimensional shift)‐shifting components, under the systemic influence of scopolamine, a muscarinic antagonist. Scopolamine impaired both reversal learning and extradimensional shifting, but was without effect on learning new discrimination problems that did not require an affective or attentional shift. Systemic administration of methylscopolamine, which does not cross the blood–brain barrier, did not impair affective or attentional set‐shifting, indicating that the scopolamine effects were centrally mediated. These data implicate muscarinic receptors in the central nervous system in the control of executive function. Taken together with other recent data, they may also suggest an important role for cholinergic receptors outside of the neocortex in regulating these aspects of attention and executive function.

Integrity signals

Registry

Crossref · 10.1111/j.1460-9568.2004.03548.x

Cites

55 of 55 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Scopolamine-induced impairments in attentional set shifting performance are consistent with a role of mAChR for mediation of cognitive functions that involve top-down control.
“Evidence indicating scopolamine-induced impairments in attentional set shifting performance (Chen et al, 2004) is consistent with a role of mAChR for the mediation of cognitive functions that involve top down control.”
From Modes and models of forebrain cholinergic neuromodulation of cognition (2011) · cites this paper as Chen et al, 2004

Statistical Methods for Psychology.
Gudgeon, A. C., & Howell, D. C. (1994) · Journal of the Royal Statistical Society Series D (The Statistician) · doi:10.2307/2348956 · Cited by 8,277
Alzheimer's Disease: A Disorder of Cortical Cholinergic Innervation
Coyle, J. T., Price, D. L., & DeLong, M. R. (1983) · Science · doi:10.1126/science.6338589 · Cited by 3,052
Dissociation in prefrontal cortex of affective and attentional shifts
Dias, R., Robbins, T. W., & Roberts, A. C. (1996) · Nature · doi:10.1038/380069a0 · Cited by 1,527
Medial Frontal Cortex Mediates Perceptual Attentional Set Shifting in the Rat
Birrell, J. M., & Brown, V. J. (2000) · The Journal of Neuroscience · doi:10.1523/jneurosci.20-11-04320.2000 · Cited by 1,421
Limbic lesions and the problem of stimulus--reinforcement associations.
Jones, B., & Mishkin, M. (1972) · Experimental Neurology · doi:10.1016/0014-4886(72)90030-1 · Cited by 864
The global record of memory in hippocampal neuronal activity
Wood, E. R., Dudchenko, P. A., & Eichenbaum, H. (1999) · Nature · doi:10.1038/17605 · Cited by 707
Extra-dimensional versus intra-dimensional set shifting performance following frontal lobe excisions, temporal lobe excisions or amygdalo-hippocampectomy in man
Owen, A. M., Roberts, A. C., Polkey, C. E., Sahakian, B. J., & Robbins, T. W. (1991) · Neuropsychologia · doi:10.1016/0028-3932(91)90063-e · Cited by 657
Orbital prefrontal cortex mediates reversal learning and not attentional set shifting in the rat
McAlonan, K., & Brown, V. J. (2003) · Behavioural Brain Research · doi:10.1016/j.bbr.2003.09.019 · Cited by 618
Dissociable Forms of Inhibitory Control within Prefrontal Cortex with an Analog of the Wisconsin Card Sort Test: Restriction to Novel Situations and Independence from “On-Line” Processing
Dias, R., Robbins, T. W., & Roberts, A. C. (1997) · The Journal of Neuroscience · doi:10.1523/jneurosci.17-23-09285.1997 · Cited by 555
Functional Specialization within Medial Frontal Cortex of the Anterior Cingulate for Evaluating Effort-Related Decisions
Walton, M. E., Bannerman, D. M., Alterescu, K., & Rushworth, M. F. S. (2003) · Journal of Neuroscience · doi:10.1523/jneurosci.23-16-06475.2003 · Cited by 512
Behavioral vigilance following infusions of 192 IgG-saporin into the basal forebrain: selectivity of the behavioral impairment and relation to cortical AChE-positive fiber density
McGaughy, J., Kaiser, T., & Sarter, M. (1996) · Behavioral Neuroscience · doi:10.1037/0735-7044.110.2.247 · Cited by 435 · cited 2×
“…the systemic scopolamine data, it might be concluded that set-shifting is not regulated by central acetylcholine, based on the absence of cholinergic lesion effects on attentional set-shifting relative to impairments in other aspects of attention following such lesions (e.g. McGaughy et al., 1996).”
Background
Cognitive functions of the basal forebrain
Baxter, M. G., & Chiba, A. A. (1999) · Current Opinion in Neurobiology · doi:10.1016/s0959-4388(99)80024-5 · Cited by 351
Self-citation
Rodent models of prefrontal cortical function
Brown, V. J., & Bowman, E. M. (2002) · Trends in Neurosciences · doi:10.1016/s0166-2236(02)02164-1 · Cited by 321
The Neuropsychology of Memory: Parallel Findings in Humans and Nonhuman Primatesa
ZOLA‐MORGAN, S., & SQUIRE, L. R. (1990) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1990.tb48905.x · Cited by 318
Lesions of orbitofrontal cortex and basolateral amygdala complex disrupt acquisition of odor-guided discriminations and reversals.Preprint
Schoenbaum, G., Setlow, B., Nugent, S. L., Saddoris, M. P., & Gallagher, M. (2003) · Learning & memory (Cold Spring Harbor, N.Y.) · doi:10.1101/lm.55203 · Cited by 317
Selective behavioral and neurochemical effects of cholinergic lesions produced by intrabasalis infusions of 192 IgG-saporin on attentional performance in a five-choice serial reaction time task
McGaughy, J., Dalley, J. W., Morrison, C. H., Everitt, B. J., & Robbins, T. W. (2002) · The Journal of Neuroscience · doi:10.1523/jneurosci.22-05-01905.2002 · Cited by 311
Differential effects of 6-OHDA lesions of the frontal cortex and caudate nucleus on the ability to acquire an attentional set
Crofts, H. S. (2001) · Cerebral Cortex · doi:10.1093/cercor/11.11.1015 · Cited by 284
Sustained Visual Attention Performance-Associated Prefrontal Neuronal Activity: Evidence for Cholinergic Modulation
Gill, T. M., Sarter, M., & Givens, B. (2000) · The Journal of Neuroscience · doi:10.1523/jneurosci.20-12-04745.2000 · Cited by 228
Further analysis of the cognitive effects of tetrahydroaminoacridine (THA) in Alzheimer's disease: assessment of attentional and mnemonic function using CANTAB
Sahakian, B. J., Owen, A. M., Morant, N. J., Eagger, S. A., Boddington, S., Crayton, L., Crockford, H. A., Crooks, M., Hill, K., & Levy, R. (1993) · Psychopharmacology · doi:10.1007/bf02244644 · Cited by 226
Luddites must not block progress in genetics
Wood, D. (1999) · Nature · doi:10.1038/16564 · Cited by 208
The frontal lobes and schizophrenia [published erratum appears in J Neuropsychiatry Clin Neurosci 1995 Winter;7(1):121]
Weinberger, D. R., Aloia, M. S., Goldberg, T. E., & Berman, K. F. (1994) · Journal of Neuropsychiatry · doi:10.1176/jnp.6.4.419 · Cited by 197
Aged Rats Are Impaired on an Attentional Set-Shifting Task Sensitive to Medial Frontal Cortex Damage in Young RatsPreprint
Barense, M. D., Fox, M. T., & Baxter, M. G. (2002) · Learning & Memory · doi:10.1101/lm.48602 · Cited by 191
Self-citation
Involvement of the dorsomedial striatum in behavioral flexibility: role of muscarinic cholinergic receptors
Ragozzino, M. E., Jih, J., & Tzavos, A. (2002) · Brain Research · doi:10.1016/s0006-8993(02)03287-0 · Cited by 171
FRONTAL LOBES AND SCHIZOPHRENIA
Greenblatt, M., & Solomon, H. C. (1954) · The American Journal of the Medical Sciences · doi:10.1097/00000441-195406000-00027 · Cited by 151
Sparing of attentional relative to mnemonic function in a subgroup of patients with dementia of the Alzheimer type.
Sahakian, B., Downes, J., Eagger, S., Everden, J. L., Levy, R., Philpot, M., Roberts, A. C., & Robbins, T. (1990) · Neuropsychologia · doi:10.1016/0028-3932(90)90055-s · Cited by 150
Attentional set-shifting in mice: modification of a rat paradigm, and evidence for strain-dependent variation
Colacicco, G., Welzl, H., Lipp, H., & Würbel, H. (2002) · Behavioural Brain Research · doi:10.1016/s0166-4328(01)00391-6 · Cited by 149
Sustained attention performance in rats with intracortical infusions of 192 IgG-saporin-induced cortical cholinergic deafferentation: Effects of Physostigmine and FG 7142.
McGaughy, J., & Sarter, M. (1998) · Behavioral Neuroscience · doi:10.1037/0735-7044.112.6.1519 · Cited by 147
Nicotine in an animal model of attention
Stolerman, I. P., Mirza, N. R., Hahn, B., & Shoaib, M. C. (2000) · European Journal of Pharmacology · doi:10.1016/s0014-2999(99)00886-9 · Cited by 144
A specific form of cognitive rigidity following excitotoxic lesions of the basal forebrain in marmosets
Roberts, A., Robbins, T. W., Everitt, B. J., & Muir, J. L. (1992) · Neuroscience · doi:10.1016/0306-4522(92)90241-s · Cited by 139
Planning impairments in frontal lobe dementia and frontal lobe lesion patients
Carlin, D., Bonerba, J., Phipps, M., Alexander, G., Shapiro, M., & Grafman, J. (2000) · Neuropsychologia · doi:10.1016/s0028-3932(99)00102-5 · Cited by 136
Detection of visual signals by rats: effects of chlordiazepoxide and cholinergic and adrenergic drugs on sustained attention
Bushnell, P. J., Oshiro, W. M., & Padnos, B. K. (1997) · Psychopharmacology · doi:10.1007/s002130050446 · Cited by 131
The effect of dopamine depletion from the caudate nucleus of the common marmoset (Callithrix jacchus) on tests of prefrontal cognitive function
Collins, P., Wilkinson, L. S., Everitt, B. J., Robbins, T. W., & Roberts, A. C. (2000) · Behavioral Neuroscience · doi:10.1037/0735-7044.114.1.3 · Cited by 129
Effect of scopolamine on visual attention in rats
Jones, D. N. C., & Higgins, G. A. (1995) · Psychopharmacology · doi:10.1007/bf02246186 · Cited by 115
The role of nicotinic and muscarinic acetylcholine receptors in attention
Mirza, N. R., & Stolerman, I. P. (2000) · Psychopharmacology · doi:10.1007/s002130050048 · Cited by 112
Perceptual Attentional Set-Shifting Is Impaired in Rats with Neurotoxic Lesions of Posterior Parietal Cortex
Fox, M. T., Barense, M. D., & Baxter, M. G. (2003) · Journal of Neuroscience · doi:10.1523/jneurosci.23-02-00676.2003 · Cited by 105
Self-citation
Two types of cholinergic projections to the rat amygdala
Heckers, S., & Mesulam, M.-M. (1994) · Neuroscience · doi:10.1016/0306-4522(94)90252-6 · Cited by 105
Muscarinic cholinergic neuromodulation reduces proactive interference between stored odor memories during associative learning in rats.
Rosa, E. D., & Hasselmo, M. E. (2000) · Behavioral Neuroscience · doi:10.1037/0735-7044.114.1.32 · Cited by 96
Acetylcholine actions in the dorsomedial striatum support the flexible shifting of response patterns
Ragozzino, M. E. (2003) · Neurobiology of Learning and Memory · doi:10.1016/s1074-7427(03)00077-7 · Cited by 93
An involvement of acetylcholine in object discrimination learning and memory in the marmoset
Ridley, R. M., Bowes, P., Baker, H. F., & Crow, T. J. (1984) · Neuropsychologia · doi:10.1016/0028-3932(84)90073-3 · Cited by 88
Distribution of muscarinic receptor subtypes in rat brain from postnatal to old age
Tice, M. A. B., Hashemi, T., Taylor, L. A., & McQuade, R. D. (1996) · Developmental Brain Research · doi:10.1016/0165-3806(95)01515-9 · Cited by 87
Deficit in Selective and Divided Attention Associated with Cholinergic Basal Forebrain Immunotoxic Lesion Produced by 192-Saporin; Motoric/Sensory Deficit Associated with Purkinje Cell Immunotoxic Lesion Produced by OX7-Saporin
Waite, J. J., Wardlow, M. L., & Power, A. E. (1999) · Neurobiology of Learning and Memory · doi:10.1006/nlme.1998.3884 · Cited by 80
Effects of cholinergic drugs on extracellular levels of acetylcholine and choline in rat cortex, hippocampus and striatum studied by brain dialysis
Toide, K., & Arima, T. (1989) · European Journal of Pharmacology · doi:10.1016/0014-2999(89)90510-4 · Cited by 74
Glutamate receptor binding in the frontal cortex and dorsal striatum of aged rats with impaired attentional set‐shifting
Nicolle, M. M., & Baxter, M. G. (2003) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2003.03077.x · Cited by 73
Self-citation
Age-dependent modulation of in vivo cortical acetylcholine release by benzodiazepine receptor ligands
Moore, H. M., Sarter, M. F., & Bruno, J. P. (1992) · Brain Research · doi:10.1016/0006-8993(92)91527-l · Cited by 72
Involvement of the prefrontal cortex but not the dorsal hippocampus in the attention-enhancing effects of nicotine in rats
Hahn, B., Shoaib, M. C., & Stolerman, I. P. (2003) · Psychopharmacology · doi:10.1007/s00213-003-1438-6 · Cited by 70
Reversal of a Vigilance Decrement in the Aged Rat by Subtype-Selective Nicotinic Ligands
Grottick, A. J., Haman, M., Wyler, R., & Higgins, G. A. (2002) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300102 · Cited by 68
Interactions between 192-IgG saporin and intraseptal cholinergic and GABAergic drugs: Role of cholinergic medial septal neurons in spatial working memory.
Pang, K. C. H., & Nocera, R. (1999) · Behavioral Neuroscience · doi:10.1037//0735-7044.113.2.265 · Cited by 63
Interactions between 192-IgG saporin and intraseptal cholinergic and GABAergic drugs: Role of cholinergic medial septal neurons in spatial working memory.
Pang, K. C. H., & Nocera, R. (1999) · Behavioral Neuroscience · doi:10.1037/0735-7044.113.2.265 · Cited by 57
Comparative Cognitive Neuropsychological Studies of Frontal Lobe Function: Implications for Therapeutic Strategies in Frontal Variant Frontotemporal Dementia
Rahman, S., Robbins, T. W., & Sahakian, B. J. (1999) · Dementia and Geriatric Cognitive Disorders · doi:10.1159/000051207 · Cited by 54
Blockade of muscarinic, rather than nicotinic, receptors impairs attention, but does not interact with serotonin depletion
Ruotsalainen, S., Miettinen, R., MacDonald, E., Koivisto, E., & Sirviö, J. (2000) · Psychopharmacology · doi:10.1007/s002130050032 · Cited by 51
Cholinergic modulation of covert attention in the rat
Stewart, C., Burke, S., & Marrocco, R. T. (2001) · Psychopharmacology · doi:10.1007/s002130100692 · Cited by 50
Quantitative in vivo receptor binding. I. Theory and application to the muscarinic cholinergic receptor
Frey, K. A., Ehrenkaufer, R. L., Beaucage, S. L., & Agranoff, B. (1985) · Journal of Neuroscience · doi:10.1523/jneurosci.05-02-00421.1985 · Cited by 45
Pharmacological Treatment of Alzheimer's Disease: Molecular and Neurobiological Foundations
Tariot, P. N. (1997) · Archives of Neurology · doi:10.1001/archneur.1997.00550240009003 · Cited by 28
Scopolamine disrupts visual reversal without affecting the first discrimination
Soffié, M., & Lamberty, Y. (1987) · Physiology & Behavior · doi:10.1016/0031-9384(87)90218-6 · Cited by 21
Effects of Chlordiazepoxide and Scopolamine, But Not Aging, on the Detection and Identification of Conditional Visual Stimuli
McGaughy, J. A., & Sarter, M. F. (1995) · The Journals of Gerontology Series A · doi:10.1093/gerona/50a.2.b90 · Cited by 20

Flagged first, then by citations

Research works printed but not linked: 5

Baxter M.G., 2002, Neuropsychology of Memory, 425
Blackwell A.D., 2000, Program No. 837.13. 2000 Abstract Viewer/Itinerary Planner
Izquierdo A., 2003, Program No. 90.2. 2003 Abstract Viewer/Itinerary Planner
McGaughy J.A., 2002, Program No. 674.4. 2002 Abstract Viewer/Itinerary Planner
Tait D.S., 2002, Program No. 286.2. 2002 Abstract Viewer/Itinerary Planner

Sorted by citations

Modes and models of forebrain cholinergic neuromodulation of cognition
Hasselmo, M. E., & Sarter, M. (2011) · Neuropsychopharmacology · doi:10.1038/npp.2010.104 · Cited by 733
The validity of scopolamine as a pharmacological model for cognitive impairment: A review of animal behavioral studies
Klinkenberg, I., & Blokland, A. (2010) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2010.04.001 · Cited by 714
Multi-target strategies for the improved treatment of depressive states: Conceptual foundations and neuronal substrates, drug discovery and therapeutic application
Millan, M. J. (2006) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2005.11.006 · Cited by 567
The neural and genetic basis of executive function: Attention, cognitive flexibility, and response inhibition
Logue, S. F., & Gould, T. J. (2014) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2013.08.007 · Cited by 477
Chronic Unpredictable Stress Induces a Cognitive Deficit and Anxiety-Like Behavior in Rats that is Prevented by Chronic Antidepressant Drug Treatment
Bondi, C. O., Rodriguez, G., Gould, G. G., Frazer, A., & Morilak, D. A. (2008) · Neuropsychopharmacology · doi:10.1038/sj.npp.1301410 · Cited by 398
Prefrontal Serotonin Depletion Affects Reversal Learning But Not Attentional Set Shifting
Clarke, H. F., Walker, S. C., Crofts, H. S., Dalley, J. W., Robbins, T. W., & Roberts, A. C. (2005) · The Journal of Neuroscience · doi:10.1523/jneurosci.3690-04.2005 · Cited by 358
Noradrenergic modulation of cognitive function in rat medial prefrontal cortex as measured by attentional set shifting capability
Bluhm, M. D. L., & Morilak, D. A. (2005) · Neuroscience · doi:10.1016/j.neuroscience.2005.09.031 · Cited by 325
Using the MATRICS to guide development of a preclinical cognitive test battery for research in schizophrenia
Young, J. W., Powell, S. B., Risbrough, V. B., Marston, H. M., & Geyer, M. A. (2009) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2009.02.004 · Cited by 312
Differential regulation of fronto-executive function by the monoamines and acetylcholine
Robbins, T., & Roberts, A. (2007) · Cerebral Cortex · doi:10.1093/cercor/bhm066 · Cited by 279
Noradrenergic, but not cholinergic, deafferentation of prefrontal cortex impairs attentional set-shifting
McGaughy, J., Ross, R. S., & Eichenbaum, H. (2008) · Neuroscience · doi:10.1016/j.neuroscience.2008.01.064 · Cited by 226
PDE10A inhibition reverses subchronic PCP‐induced deficits in attentional set‐shifting in rats
Rodefer, J. S., Murphy, E. R., & Baxter, M. G. (2005) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2005.03937.x · Cited by 199
Self-citation
The Role of Acetylcholine in Cocaine Addiction
Williams, M. J., & Adinoff, B. H. (2007) · Neuropsychopharmacology · doi:10.1038/sj.npp.1301585 · Cited by 173
Behavioural Assays to Model Cognitive and Affective Dimensions of Depression and Anxiety in Rats
Lapiz‐Bluhm, M. D. S., Bondi, C. O., Doyen, J., Rodriguez, G. A., Bédard‐Arana, T., & Morilak, D. A. (2008) · Journal of Neuroendocrinology · doi:10.1111/j.1365-2826.2008.01772.x · Cited by 174
The Free-movement pattern Y-maze: A cross-species measure of working memory and executive function
Cleal, M., Fontana, B. D., Ranson, D. C., McBride, S. D., Swinny, J. D., Redhead, E. S., & Parker, M. O. (2020) · Behavior Research Methods · doi:10.3758/s13428-020-01452-x · Cited by 159
Cholinergic circuits in cognitive flexibility
Prado, V. F., Janíčková, H., Al‐Onaizi, M., & Prado, M. A. M. (2016) · Neuroscience · doi:10.1016/j.neuroscience.2016.09.013 · Cited by 156
Role of Striatal Cholinergic Interneurons in Set-Shifting in the Rat
Aoki, S., Liu, A. W., Zucca, A., Zucca, S., & Wickens, J. R. (2015) · Journal of Neuroscience · doi:10.1523/jneurosci.0490-15.2015 · Cited by 137
Reversal of subchronic PCP-induced deficits in attentional set shifting in rats by sertindole and a 5-HT6 receptor antagonist: comparison among antipsychotics
Rodefer, J. S., Nguyen, T. N., Karlsson, J.-J., & Arnt, J. (2008) · Neuropsychopharmacology · doi:10.1038/sj.npp.1301654 · Cited by 126
Self-citation
Muscarinic Receptor Pharmacology and Circuitry for the Modulation of Cognition
Bubser, M., Byun, N. E., Wood, M. R., & Jones, C. K. (2011) · Handbook of experimental pharmacology · doi:10.1007/978-3-642-23274-9_7 · Cited by 130
Using the pharmacology of latent inhibition to model domains of pathology in schizophrenia and their treatment
Weiner, I., & Arad, M. (2009) · Behavioural Brain Research · doi:10.1016/j.bbr.2009.05.004 · Cited by 119
Animal Models of Schizophrenia
Young, J. W., Zhou, X., & Geyer, M. A. (2010) · Current topics in behavioral neurosciences · doi:10.1007/7854_2010_62 · Cited by 97
Chronic treatment with desipramine improves cognitive performance of rats in an attentional set-shifting test
Lapiz, M. D. S., Bondi, C. O., & Morilak, D. A. (2007) · Neuropsychopharmacology · doi:10.1038/sj.npp.1301235 · Cited by 95
Preventive Action of Kai Xin San Aqueous Extract on Depressive-Like Symptoms and Cognition Deficit Induced by Chronic Mild Stress
Dang, H., Sun, L., Liu, X., Peng, B., Wang, Q., Jia, W. W.-G., Chen, Y., Pan, A., & Xiao, P. (2009) · Experimental Biology and Medicine · doi:10.3181/0812-rm-354 · Cited by 93
Experimental Sleep Fragmentation Impairs Attentional Set-Shifting in Rats
McCoy, J. G., Tartar, J. L., Bebis, A. C., Ward, C. P., McKenna, J. T., Baxter, M. G., McGaughy, J. A., McCarley, R. W., & Strecker, R. E. (2007) · SLEEP · doi:10.1093/sleep/30.1.52 · Cited by 83
Self-citation
Measuring the construct of executive control in schizophrenia: Defining and validating translational animal paradigms for discovery research
Gilmour, G., Arguello, P. A., Bari, A., Brown, V. J., Carter, C., Floresco, S., Jentsch, J. D., Tait, D. S., Young, J. W., & Robbins, T. W. (2012) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2012.04.006 · Cited by 81
Selective phosphodiesterase inhibitors improve performance on the ED/ID cognitive task in rats
Rodefer, J. S., Saland, S. K., & Eckrich, S. J. (2011) · Neuropharmacology · doi:10.1016/j.neuropharm.2011.08.008 · Cited by 74
Self-citation
Learning and memory: Steroids and epigenetics
Colciago, A., Casati, L., Negri‐Cesi, P., & Celotti, F. (2015) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2015.02.008 · Cited by 74
Lesions of the basal forebrain impair reversal learning but not shifting of attentional set in rats
Tait, D. S., & Brown, V. J. (2007) · Behavioural Brain Research · doi:10.1016/j.bbr.2007.08.035 · Cited by 70
Systemic Inflammation Impairs Attention and Cognitive Flexibility but Not Associative Learning in Aged Rats: Possible Implications for Delirium
Culley, D. J., Snayd, M., Baxter, M. G., Xie, Z., Lee, I. H., Rudolph, J. L., Inouye, S. K., Marcantonio, E. R., & Crosby, G. J. (2014) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2014.00107 · Cited by 70
Self-citation
The dopamine D3 receptor antagonist, S33138, counters cognitive impairment in a range of rodent and primate procedures
Millan, M. J., Buccafusco, J. J., Loiseau, F., Watson, D. J., Decamp, E., Fone, K. C. F., Thomasson, N., Hill, M. P., Mocaër, E., & Schneider, J. S. (2010) · The International Journal of Neuropsychopharmacology · doi:10.1017/s1461145710000775 · Cited by 71
Adolescent binge ethanol exposure alters specific forebrain cholinergic cell populations and leads to selective functional deficits in the prefrontal cortex
Fernandez, G. M., & Savage, L. M. (2017) · Neuroscience · doi:10.1016/j.neuroscience.2017.08.013 · Cited by 67
Muscarinic Receptors, from Synaptic Plasticity to its Role in Network Activity
de Sevilla, D. F., Núñez, Á., & Buño, W. (2020) · Neuroscience · doi:10.1016/j.neuroscience.2020.04.005 · Cited by 67
Evaluation of a neurodevelopmental model of schizophrenia—Early postnatal PCP treatment in attentional set-shifting
Broberg, B. V., Dias, R., Glenthoj, B. Y., & Olsen, C. K. (2008) · Behavioural Brain Research · doi:10.1016/j.bbr.2008.02.020 · Cited by 65
Nicotine improves performance in an attentional set shifting task in rats
Allison, C., & Shoaib, M. C. (2012) · Neuropharmacology · doi:10.1016/j.neuropharm.2012.06.055 · Cited by 61
The M1/M4 preferring agonist xanomeline reverses amphetamine-, MK801- and scopolamine-induced abnormalities of latent inhibition: putative efficacy against positive, negative and cognitive symptoms in schizophrenia
Barak, S., & Weiner, I. (2011) · The International Journal of Neuropsychopharmacology · doi:10.1017/s1461145710001549 · Cited by 60
α7 nicotinic acetylcholine receptor activation ameliorates scopolamine-induced behavioural changes in a modified continuous Y-maze task in mice
Redrobe, J. P., Nielsen, E. Ø., Christensen, J. K., Peters, D., Timmermann, D. B., & Olsen, G. M. (2008) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2008.09.035 · Cited by 57
NMDA and dopamine interactions in the nucleus accumbens modulate cortical acetylcholine release
Zmarowski, A., Sarter, M., & Bruno, J. P. (2005) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2005.04333.x · Cited by 52
The impact of cafeteria diet feeding on physiology and anxiety-related behaviour in male and female Sprague–Dawley rats of different ages
Warneke, W., Klaus, S., Fink, H., Langley‐Evans, S. C., & Voigt, J. (2013) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2013.11.016 · Cited by 56
Potentiation of anti-Alzheimer activity of curcumin by probiotic Lactobacillus rhamnosus UBLR-58 against scopolamine-induced memory impairment in mice
Patel, C. A., Pande, S. V., & Acharya, S. (2020) · Naunyn-Schmiedeberg s Archives of Pharmacology · doi:10.1007/s00210-020-01904-3 · Cited by 52
Putative cognitive enhancers in preclinical models related to schizophrenia: The search for an elusive target
Barak, S., & Weiner, I. (2011) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2011.03.011 · Cited by 51
Effects of quetiapine and sertindole on subchronic ketamine-induced deficits in attentional set-shifting in rats
Nikiforuk, A., & Popik, P. (2011) · Psychopharmacology · doi:10.1007/s00213-011-2487-x · Cited by 48
Modeling cholinergic aspects of schizophrenia: Focus on the antimuscarinic syndrome
Barak, S. (2009) · Behavioural Brain Research · doi:10.1016/j.bbr.2009.04.006 · Cited by 50
Effects of Selective Activation of M1 and M4 Muscarinic Receptors on Object Recognition Memory Performance in Rats
Galloway, C. R., Lebois, E. P., Shagarabi, S. L., Hernandez, N. A., & Manns, J. R. (2014) · Pharmacology · doi:10.1159/000357682 · Cited by 46
Selective extra-dimensional set shifting deficit in a knock-in mouse model of Huntington's disease
Brooks, S. P., Betteridge, H., Trueman, R. C., Jones, L., & Dunnett, S. B. (2006) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2006.02.011 · Cited by 42
Towards an animal model of an antipsychotic drug-resistant cognitive impairment in schizophrenia: scopolamine induces abnormally persistent latent inhibition, which can be reversed by cognitive enhancers but not by antipsychotic drugs
Barak, S., & Weiner, I. (2008) · The International Journal of Neuropsychopharmacology · doi:10.1017/s1461145708009176 · Cited by 39
Altered Neural Cholinergic Receptor Systems in Cocaine-Addicted Subjects
Adinoff, B. H., Devous, M. D., Williams, M. J., Best, S. E., Harris, T. S., Minhajuddin, A., Zielinski, T., & Cullum, C. M. (2010) · Neuropsychopharmacology · doi:10.1038/npp.2010.18 · Cited by 38
Naltrexone reverses age-induced cognitive deficits in rats
Rodefer, J. S., & Nguyen, T. N. (2006) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2006.10.005 · Cited by 35
Self-citation
Alpha lipoic acid ameliorates scopolamine induced memory deficit and neurodegeneration in the cerebello-hippocampal cortex
Memudu, A. E., & Adewumi, A. E. (2021) · Metabolic Brain Disease · doi:10.1007/s11011-021-00720-9 · Cited by 33
Aged dogs demonstrate both increased sensitivity to scopolamine impairment and decreased muscarinic receptor density
Araujo, J. A., Nóbrega, J. N., Raymond, R., & Milgram, N. W. (2011) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2011.01.005 · Cited by 28
Cognitive effects of dopamine depletion in the context of diminished acetylcholine signaling capacity in mice
Zurkovsky, L., Бычков, Э. Р., Tsakem, E. L., Siedlecki, C., Blakely, R., & Gurevich, E. V. (2012) · Disease Models & Mechanisms · doi:10.1242/dmm.010363 · Cited by 29
Executive Function
Talpos, J. C., & Shoaib, M. C. (2015) · Handbook of experimental pharmacology · doi:10.1007/978-3-319-16522-6_6 · Cited by 27
Central muscarinic blockade interferes with retrieval and reacquisition of active allothetic place avoidance despite spatial pretraining
Valeš, K., & Stuchlı́k, A. (2005) · Behavioural Brain Research · doi:10.1016/j.bbr.2005.02.012 · Cited by 27
Effects of milnacipran on cognitive flexibility following chronic stress in rats
Naegeli, K. J., O’Connor, J. A., Banerjee, P., & Morilak, D. A. (2013) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2013.02.006 · Cited by 26
Role of acetylcholine in negative patterning in turtles (Chrysemys picta).
Powers, A. S., Hogue, P., Lynch, C., Gattuso, B., Lissek, S. M., & Nayal, C. (2009) · Behavioral Neuroscience · doi:10.1037/a0016320 · Cited by 23
Cognition Enhancing Activity of Sulforaphane Against Scopolamine Induced Cognitive Impairment in Zebra Fish (Danio rerio)
Rajesh, V., & Ilanthalir, S. (2016) · Neurochemical Research · doi:10.1007/s11064-016-1965-2 · Cited by 23
The cholinergic system in Down's syndrome
Fodale, V., Mafrica, F., Caminiti, V., & Grasso, G. (2006) · Journal of Intellectual Disabilities · doi:10.1177/1744629506067615 · Cited by 22
Long-Term Effect of Porcine Brain Enzyme Hydrolysate Intake on Scopolamine-Induced Memory Impairment in Rats
Zhang, T., Kim, M. J., Kim, M. J., Wu, X., Yang, H. J., Yuan, H., Huang, S., Yoon, S. M., Kim, K.-N., & Park, S. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23063361 · Cited by 21
Antagonism of muscarinic acetylcholine receptors in medial prefrontal cortex disrupts the context preexposure facilitation effect
Robinson-Drummer, P. A., Heroux, N. A., & Stanton, M. E. (2017) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2017.04.003 · Cited by 20
Effects of acute administration of the GABA(B) receptor agonist baclofen on behavioral flexibility in rats
Beas, B. S., Setlow, B., & Bizon, J. L. (2016) · Psychopharmacology · doi:10.1007/s00213-016-4321-y · Cited by 18
The influence of COMT rs4680 on functional connectivity in healthy adults: A systematic review
Morris, K. A., Grace, S., Woods, W., Dean, B., & Rossell, S. L. (2020) · European Journal of Neuroscience · doi:10.1111/ejn.14748 · Cited by 18
A preclinical cognitive test battery to parallel the National Institute of Health Toolbox in humans: bridging the translational gap
Snigdha, S., Milgram, N. W., Willis, S. L., Albert, M. S., Weıntraub, S., Fortin, N. J., & Cotman, C. W. (2013) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2013.01.018 · Cited by 21
Comparison of scopolamine-induced cognitive impairment responses in three different ICR stocks
Yoon, W. B., Choi, H. J., Kim, J. E., Park, J. W., Kang, M. J., Bae, S. J., Lee, Y. J., Choi, Y. S., Kim, K., Jung, Y.-S., et al. (2018) · Laboratory Animal Research · doi:10.5625/lar.2018.34.4.317 · Cited by 17
Muscarinic Receptor Antagonists in Rats
Terry, A. V. (2006) · Frontiers in neuroscience · doi:10.1201/9781420004335.sec1 · Cited by 17
Evaluation of muscarinic and nicotinic receptor antagonists on attention and working memory
McQuail, J. A., & Burk, J. A. (2006) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2006.11.015 · Cited by 16
Atomoxetine accelerates attentional set shifting without affecting learning rate in the rat
Totah, N. K. B., Logothetis, N. K., & Eschenko, O. (2015) · Psychopharmacology · doi:10.1007/s00213-015-4028-5 · Cited by 16
Tacrine improves reversal learning in older rats
Tait, D. S., Chase, E. A., & Brown, V. J. (2013) · Neuropharmacology · doi:10.1016/j.neuropharm.2013.05.036 · Cited by 15
Discrimination and avoidance learning in adult mice following developmental exposure to diisopropylfluorophosphate
Levi, Y., Kofman, O., SCHWEBEL, M., & Shaldubina, A. (2007) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2007.09.017 · Cited by 13
Effects of chronic tramadol administration on cognitive flexibility in mice
Attoh-Mensah, E., Léger, M., Loggia, G., Fréret, T., Chavoix, C., & Schumann‐Bard, P. (2021) · Psychopharmacology · doi:10.1007/s00213-021-05903-x · Cited by 12
Environmental enrichment ameliorates phencyclidine-induced cognitive deficits
Saland, S. K., & Rodefer, J. S. (2011) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2011.02.014 · Cited by 12
Self-citation
Varenicline, the clinically effective smoking cessation agent, restores probabilistic response reversal performance during withdrawal from nicotine
Jackson, A. E., Silk, S., Buhidma, Y., & Shoaib, M. C. (2016) · Addiction Biology · doi:10.1111/adb.12423 · Cited by 12
Dissociating scopolamine-induced disrupted and persistent latent inhibition: stage-dependent effects of glycine and physostigmine
Barak, S., & Weiner, I. (2010) · Psychopharmacology · doi:10.1007/s00213-010-1785-z · Cited by 11
Precautionary Ellagic Acid Treatment Ameliorates Chronically Administered Scopolamine Induced Alzheimer's Type Memory and Cognitive Dysfunctions in Rats
Mehan, S., Kaur, R., Khanna, D., Kalra, S., & Parveen, S. (2015) · Pharmacologia · doi:10.5567/pharmacologia.2015.192.212 · Cited by 11
D-cycloserine rescues scopolamine-induced deficits in cognitive flexibility in rats measured by the attentional set-shifting task
Siddik, M. A. B., & Fendt, M. (2022) · Behavioural Brain Research · doi:10.1016/j.bbr.2022.113961 · Cited by 12
M4 Muscarinic Receptors and Locomotor Activity Regulation
Mysliveček, J., Farár, V., & Valuskova, P. (2017) · Physiological Research · doi:10.33549/physiolres.933796 · Cited by 10
Interaction of cholinergic disruption and age on cognitive flexibility in rats
Cammarata, C. M., & Rosa, E. D. (2022) · Experimental Brain Research · doi:10.1007/s00221-022-06472-x · Cited by 9
White matter integrity as a mediator between socioeconomic status and executive function
Shaked, D., Katzel, L. I., Davatzikos, C. A., Gullapalli, R. P., Seliger, S. L., Erus, G., Evans, M. K., Zonderman, A. B., & Waldstein, S. R. (2022) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2022.1021857 · Cited by 9
Pyrethroid and Chlorpyrifos Pesticide Exposure, General Intellectual Abilities, and Executive Functions of School Children from Montevideo, Uruguay
Rodríguez, D., Barg, G., Queirolo, E. I., Olson, J. R., Mañáy, N., & Kordas, K. (2023) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph20075288 · Cited by 9
The atypical antipsychotic olanzapine disturbs depotentiation by modulating mAChRs and impairs reversal learning
Song, W. S., Cha, J. H., Yoon, S. H., Cho, Y. S., Park, K.-Y., & Kim, M. (2016) · Neuropharmacology · doi:10.1016/j.neuropharm.2016.11.012 · Cited by 10
5-HT6 Receptors as Targets for the Treatment of Cognitive Deficits in Schizophrenia
Schreiber, R., Sleight, A. J., & Woolley, M. L. (2006) · The Receptors · doi:10.1007/978-1-59745-080-5_17 · Cited by 7
Methods and Models of the Nonmotor Symptoms of Parkinson Disease
McDonald, M. P. (2014) · Elsevier eBooks · doi:10.1016/b978-0-12-405195-9.00023-8 · Cited by 6
Basal Forebrain and Memory
Chiba, A. A., & Quinn, L. K. (2008) · Elsevier eBooks · doi:10.1016/b978-012370509-9.00110-8 · Cited by 6
Systematic review: Effects of cholinergic signaling on cognition in human pharmacological studies
Dan, Y. R., Christakou, A., & Roelofs, K. (2025) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2025.106408 · Cited by 5
Executive functioning: perspectives on neurotrophic activity and pharmacology
Sun, M. (2018) · Behavioural Pharmacology · doi:10.1097/fbp.0000000000000427 · Cited by 5
Pharmacologically Manipulating Learning and Memory
Fortress, A. M., & Frick, K. M. (2014) · Neuromethods · doi:10.1007/978-1-4939-2159-1_7 · Cited by 3
New Variations for Strategy Set-shifting in the Rat
Aoki, S., Liu, A. W., Zucca, A., Zucca, S., & Wickens, J. R. (2017) · Journal of Visualized Experiments · doi:10.3791/55005 · Cited by 3
The pharmacology of latent inhibition and its relevance to schizophrenia
Weiner, I., & Arad, M. (2010) · Cambridge University Press eBooks · doi:10.1017/cbo9780511730184.014 · Cited by 3
The Role of Acetylcholine in Attention in Turtles (Chrysemys picta)
Naimoli, V., Donnelly-Greenberg, J., Gabel, N., Libby, D. J., Panigrosso, E. R., Rhindress, K., & Powers, A. S. (2018) · Brain Behavior and Evolution · doi:10.1159/000492052 · Cited by 2
Cholinergic System Structure and Function Changes in Individuals with Down Syndrome During the Development of Alzheimer’s Disease
Russell, J. K., Conley, A. C., Wilson, J. E., & NEWHOUSE, P. A. (2024) · Current topics in behavioral neurosciences · doi:10.1007/7854_2024_523 · Cited by 3
The Roles of Nicotinic and Muscarinic Cholinergic Receptors in Risky and Impulsive Decision Making
Mendez, I. A. (2010) · OakTrust (Texas A&M University Libraries) · Cited by 2
The Novel Functions of M4 Muscarinic Receptors
Mysliveček, J., & Janisova, K. (2025) · Physiological Research · doi:10.33549/physiolres.935750 · Cited by 1
White matter fibers mediate the relationship between workload, resource use, and burnout: a new attempt to apply the conservation of resources theory to neuroscience
Kokubun, K., Nemoto, K., & Yamakawa, Y. (2026) · Brain Structure and Function · doi:10.1007/s00429-026-03099-4 · Cited by 1
Postnatal exposure to diisopropylfluorophosphate enhances discrimination learning in adult mice
Kofman, O., & Sher, T. (2006) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2006.02.006 · Cited by 1
New Variations for Strategy Set-shifting in the Rat
Aoki, S., Liu, A. W., Zucca, A., Zucca, S., & Wickens, J. R. (2017) · Journal of Visualized Experiments · doi:10.3791/55005-v · Cited by 1
Effect of Lactobacillus rhamnosus and Diclofenac with Curcumin for Neuronal Restoration and Repair Against Scopolamine Induced Dementia in Zebrafish (Danio rerio)
Pande, S. V., & Patel, C. A. (2023) · Current Enzyme Inhibition · doi:10.2174/1573408019666230508155702 · Cited by 1
Muscarinic M1 receptor modulation of cognition using a translational approach : relevance for dementia and schizophrenia
Klinkenberg, I. (2012) · doi:10.26481/dis.20121213ik
Striatal acetylcholine enables behavioral flexibility
(2016) · Neurotransmitter · doi:10.14800/nt.1086
Astrocytes Regulate Cortical Ach Release Via Kynurenic Acid: Implications For Cognitive Impairments In Schizophrenia
Zmarowski, A. (2008) · OhioLink ETD Center (Ohio Library and Information Network)
Adolescent nicotine administration impacts working memory and reversal learning but not cognitive flexibility
Rodefer, J. S., & Maitland, S. C. (2022) · Developmental Psychobiology · doi:10.1002/dev.22343
Self-citation

Muscarinic antagonist effects on executive control of attention
Thienel, R., Kellermann, T., Schall, U., Voß, B., Reske, M., Halfter, S., Sheldrick, A. J., Radenbach, K., Habel, U., Shah, N. J., et al. (2009) · The International Journal of Neuropsychopharmacology · doi:10.1017/s146114570999068x · Cited by 49
Blockade of muscarinic, rather than nicotinic, receptors impairs attention, but does not interact with serotonin depletion
Ruotsalainen, S., Miettinen, R., MacDonald, E., Koivisto, E., & Sirviö, J. (2000) · Psychopharmacology · doi:10.1007/s002130050032 · Cited by 51
Effect of muscarinic blockade on the speed of attention shifting and learningPreprint
Thiele, A., Milner, A. M., Hall, C., Mayhew, L., Carter, A., & Sanjeev, S. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.05.08.593141
Central Cholinergic Involvement in Learning and Memory
Spencer, D. G., & Lal, H. (1985) · Springer eBooks · doi:10.1007/978-1-4684-1218-5_5 · Cited by 7
Scopolamine slows the orienting of attention in primates to cued visual targets
Davidson, M. C., Cutrell, E. B., & Marrocco, R. T. (1999) · Psychopharmacology · doi:10.1007/s002130050855 · Cited by 61

Authors: Chen, K. C., Baxter, M. G., & Rodefer, J. S.
Affiliations: Harvard University (US)
University of Iowa (US)
Corresponding author: Rodefer, Joshua S.
ORCID: Baxter, Mark G.
Rodefer, Joshua S.
Venue: European Journal of Neuroscience
Publisher: Wiley
Published: 2004-08
Volume: 20
Issue: 4
Pages: 1081-1088
ISSN: 0953-816X (ISSN-L)
1460-9568
DOI: 10.1111/j.1460-9568.2004.03548.x
OpenAlex: W2043922259
Cited by: 97
References: 54
Citations by year: 2026: 1 · 2025: 2 · 2024: 1 · 2023: 2 · 2022: 5 · 2021: 2 · 2020: 4 · 2018: 3 · 2017: 5 · 2016: 6 · 2015: 5 · 2014: 4 · 2013: 5 · 2012: 4
FWCI: 2.46
Type: journal article
Language: en
Open access: closed
Licence: onlinelibrary.wiley.com/termsAndConditions#vor (vor, 3 d)
Locations: European Journal of Neuroscience (publishedVersion)
PubMed (publishedVersion)
Topics: Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
Keywords: muscarinic receptors, scopolamine, methylscopolamine, set-shifting, executive function, reversal learning, extradimensional shift, discrimination learning, cholinergic neurons, prefrontal cortex, blood-brain barrier
MeSH terms: Animals, Attention, Learning, Male, Receptors, Muscarinic, Scopolamine, Muscarinic Antagonists, Rats, Long-Evans, Rats

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Central blockade of muscarinic cholinergic receptors disrupts affective and attentional set‐shifting

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks