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Neurocognition in first-episode schizophrenia: A meta-analytic review.

Mesholam-Gately, Raquelle I., Giuliano, Anthony J., Goff, Kirsten P., Faraone, Stephen V., Seidman, Larry J.·2009·Neuropsychology

DOI 10.1037/a0014708

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Abstract

Compromised neurocognition is a core feature of schizophrenia. Following Heinrichs and Zakzanis's (1998) seminal meta-analysis of middle-aged and predominantly chronic schizophrenia samples, the aim of this study is to provide a meta-analysis of neurocognitive findings from 47 studies of first-episode (FE) schizophrenia published through October 2007. The meta-analysis uses 43 separate samples of 2,204 FE patients with a mean age of 25.5 and 2,775 largely age- and gender-matched control participants. FE samples demonstrated medium-to-large impairments across 10 neurocognitive domains (mean effect sizes from -0.64 to -1.20). Findings indicate that impairments are reliably and broadly present by the FE, approach or match the degree of deficit shown in well-established illness, and are maximal in immediate verbal memory and processing speed. Larger IQ impairments in the FE compared to the premorbid period, but comparable to later phases of illness suggests deterioration between premorbid and FE phases followed by deficit stability at the group level. Considerable heterogeneity of effect sizes across studies, however, underscores variability in manifestations of the illness and a need for improved reporting of sample characteristics to support moderator variable analyses.

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Diagnostic and Statistical Manual of Mental Disorders
Williams, J. B. W., & First, M. B. (2013) · Oxford University Press eBooks · doi:10.1093/acrefore/9780199975839.013.104 · Cited by 109,845
Statistical power analysis for the behavioral sciences
Cohen, J. (1990) · Computers Environment and Urban Systems · doi:10.1016/0198-9715(90)90050-4 · Cited by 65,417
Bias in meta-analysis detected by a simple, graphical test
Egger, M., Smith, G. D., Schneider, M., & Minder, C. (1997) · BMJ · doi:10.1136/bmj.315.7109.629 · Cited by 56,722
Meta-analysis in clinical trials
DerSimonian, R., & Laird, N. (1986) · Controlled Clinical Trials · doi:10.1016/0197-2456(86)90046-2 · Cited by 39,552
Statistical Power Analysis for the Behavioral Sciences (2nd ed.).
Lachenbruch, P. A., & Cohen, J. (1989) · Journal of the American Statistical Association · doi:10.2307/2290095 · Cited by 37,421
Studies of interference in serial verbal reactions
Stroop, J. R. (1935) · Journal of Experimental Psychology · doi:10.1037/h0054651 · Cited by 18,622
The Unity and Diversity of Executive Functions and Their Contributions to Complex “Frontal Lobe” Tasks: A Latent Variable Analysis
Miyake, A., Friedman, N. P., Emerson, M. J., Witzki, A. H., Howerter, A., & Wager, T. D. (2000) · Cognitive Psychology · doi:10.1006/cogp.1999.0734 · Cited by 15,798
Book Reviews: Statistical Methods for Meta-Analysis Larry V. Hedges and Ingram Olkin New York: Academic Press, 1985. xxii + 369 pp
Wasserman, S. S., Hedges, L. V., & Olkin, I. (1988) · Journal of Educational Statistics · doi:10.2307/1164953 · Cited by 10,377
VALIDITY OF THE TRAIL MAKING TEST AS AN INDICATOR OF ORGANIC BRAIN DAMAGE
Reitan, R. M. (1958) · Perceptual and Motor Skills · doi:10.2466/pms.1958.8.3.271 · Cited by 8,167
Methods of Meta-Analysis: Correcting Error and Bias in Research Findings
Schmidt, F. L., & Hunter, J. E. (2015) · doi:10.4135/9781483398105 · Cited by 5,542

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McClay, J. L., Adkins, D. E., Åberg, K., Bukszár, J., Khachane, A. N., Keefe, R. S. E., Perkins, D. O., McEvoy, J. P., Stroup, T. S., Vann, R. E., et al. (2011) · Neuropsychopharmacology · doi:10.1038/npp.2010.193 · Cited by 124
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Kulak, A., Steullet, P., Cabungcal, J.-H., Werge, T., Ingason, A., Cuenod, M., & Do, K. Q. (2013) · Antioxidants & Redox Signaling · doi:10.1089/ars.2012.4858 · Cited by 124
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Bora, E., Akdede, B. B., & Alptekın, K. (2017) · Psychological Medicine · doi:10.1017/s0033291717000952 · Cited by 125
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Carruthers, S. P., Rheenen, T. E. V., Gurvich, C., Sumner, P. J., & Rossell, S. L. (2019) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2019.09.006 · Cited by 130
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He, Z., Deng, W., Li, M., Chen, Z., Jiang, L., Wang, Q., Huang, C., Collier, D. A., Gong, Q., Ma, X., et al. (2012) · Psychological Medicine · doi:10.1017/s0033291712001638 · Cited by 126
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Sponheim, S. R., Jung, R. E., Seidman, L. J., Mesholam-Gately, R. I., Manoach, D. S., O’Leary, D. S., Ho, B. C., Andreasen, N. C., Lauriello, J., & Schulz, S. C. (2010) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2009.09.010 · Cited by 123
Self-citation
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McCleery, A., Ventura, J., Kern, R. S., Subotnik, K. L., Gretchen‐Doorly, D., Green, M. F., Hellemann, G., & Nuechterlein, K. H. (2014) · Schizophrenia Research · doi:10.1016/j.schres.2014.04.039 · Cited by 125
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Mollon, J., & Reichenberg, A. (2017) · Psychological Medicine · doi:10.1017/s0033291717001970 · Cited by 130
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Kas, M. J., Penninx, B., Sommer, B., Serretti, A., Arango, C., & Marston, H. (2019) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2017.12.008 · Cited by 112
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Lee, R. S. C., Hermens, D. F., Hodge, M. A., Naismith, S. L., Porter, M. A., Kaur, M., White, D., Scott, E. M., & Hickie, I. B. (2013) · PLoS ONE · doi:10.1371/journal.pone.0058176 · Cited by 122
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Bora, E. (2016) · Psychiatry and Clinical Neurosciences · doi:10.1111/pcn.12410 · Cited by 127
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Albus, M., Hubmann, W., Mohr, F., Tiedemann, T. V., Pechler, S., Drießlein, D., & Küchenhoff, H. (2019) · European Archives of Psychiatry and Clinical Neuroscience · doi:10.1007/s00406-019-01030-z · Cited by 121
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Rund, B. R., Barder, H. E., Evensen, J. H., Haahr, U., Hegelstad, W. T. V., Joa, I., Johannessen, J. O., Langeveld, J., Larsen, T. K., Melle, I. S., et al. (2015) · Schizophrenia Bulletin · doi:10.1093/schbul/sbv083 · Cited by 121
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Lam, M., Hill, W. D., Trampush, J. W., Yu, J., Knowles, E., Davies, G., Stahl, E. A., Huckins, L. M., Liewald, D. C. M., Djurovic, S., et al. (2019) · The American Journal of Human Genetics · doi:10.1016/j.ajhg.2019.06.012 · Cited by 115
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Thootkur, M., Kraguljac, N. V., & Lahti, A. C. (2020) · Schizophrenia Research · doi:10.1016/j.schres.2020.02.001 · Cited by 114
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Woodberry, K. A., Seidman, L. J., Giuliano, A. J., Verdi, M., Cook, W. L., & McFarlane, W. R. (2010) · Schizophrenia Research · doi:10.1016/j.schres.2010.06.021 · Cited by 116
Self-citation
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Barkl, S. J., Lah, S. S., Harris, A. W. F., & Williams, L. M. (2014) · Schizophrenia Research · doi:10.1016/j.schres.2014.07.049 · Cited by 130
Executive functioning rating scales: Ecologically valid or construct invalid?
Soto, E. F., Kofler, M. J., Singh, L. J., Wells, E. L., Irwin, L. N., Groves, N. B., & Miller, C. E. (2020) · Neuropsychology · doi:10.1037/neu0000681 · Cited by 115
“Deficits in executive functions are theorized to be etiologically important for a broad range of psychopathologies, including schizophrenia (Mesholam-Gately et al., 2009), depression (Joormann & Gotlib, 2008; Snyder, 2013), bipolar disorders (Bora et al.”
Background
Early and broadly defined psychosis risk mental states
Keshavan, M. S., DeLisi, L. E., & Seidman, L. J. (2010) · Schizophrenia Research · doi:10.1016/j.schres.2010.10.006 · Cited by 111
Self-citation
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DeVito, L. M., Balu, D. T., Kanter, B. R., Lykken, C., Basu, A. C., COYLE, J. T., & Eichenbaum, H. (2010) · Genes Brain & Behavior · doi:10.1111/j.1601-183x.2010.00656.x · Cited by 114
Neuropsychological performance and family history in children at age 7 who develop adult schizophrenia or bipolar psychosis in the New England Family Studies
Seidman, L. J., Cherkerzian, S., Goldstein, J. M., Agnew-Blais, J., Tsuang, M. T., & Buka, S. L. (2013) · Psychological Medicine · doi:10.1017/s0033291712000773 · Cited by 114
Self-citation
A review of abnormalities in the perception of visual illusions in schizophrenia
Griffiths-King, D. J., Hodgekins, J., Chouinard, P. A., Chouinard, V., & Sperandio, I. (2016) · Psychonomic Bulletin & Review · doi:10.3758/s13423-016-1168-5 · Cited by 112

Authors: Mesholam-Gately, R. I., Giuliano, A. J., Goff, K. P., Faraone, S. V., & Seidman, L. J.
Affiliations: Beth Israel Deaconess Medical Center (US)
SUNY Upstate Medical University (US)
ORCID: Faraone, Stephen V.
Seidman, Larry J.
Venue: Neuropsychology
Publisher: American Psychological Association (APA)
Published: 2009
Volume: 23
Issue: 3
Pages: 315-336
ISSN: 0894-4105 (ISSN-L)
1931-1559
DOI: 10.1037/a0014708
OpenAlex: W1987834520
Semantic Scholar: 1f5bc4062ee07501c7114895394d11f0b51016c3
Cited by: 1,130
References: 133
Citations by year: 2026: 29 · 2025: 43 · 2024: 52 · 2023: 54 · 2022: 56 · 2021: 73 · 2020: 74 · 2019: 103 · 2018: 88 · 2017: 79 · 2016: 66 · 2015: 88 · 2014: 74 · 2013: 84 · 2012: 66
FWCI: 34.11
Type: journal article
Language: en
Open access: closed
Locations: Neuropsychology (publishedVersion)
PubMed (publishedVersion)
Funders: National Alliance for Research on Schizophrenia and Depression
National Institute of Mental Health (P50MH080272, MH 43518; MH 63951; MH 65562)
Department of Mental Health Research
Topics: Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
Social Sciences › Arts and Humanities › Philosophy › Mental Health and Psychiatry
Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
Keywords: first-episode schizophrenia, neurocognitive function, cognitive impairment, verbal memory, processing speed, IQ decline, premorbid intelligence, effect size heterogeneity
MeSH terms: Adult, Cognition Disorders, Humans, Intelligence, Memory, Neuropsychological Tests, Schizophrenia, Schizophrenic Psychology, Time Factors, Verbal Learning

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Neurocognition in first-episode schizophrenia: A meta-analytic review.

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