Cited by 594Smoking Behavior and CessationSubstance Abuse Treatment and OutcomesGambling Behavior and Treatments

Co‐Morbidity of Smoking in Patients with Psychiatric and Substance Use Disorders

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Kalman, David, Morissette, Sandra Baker, George, Tony P.·2005·The American Journal on Addictions

Abstract

This article reviews cigarette smoking in patients with psychiatric disorders (PD) and substance use disorders (SUD). Rates of smoking are approximately 23% in the U.S. population but approximately twoto four‐fold higher in patients with PD and SUD. Many remaining smokers have had repeated smoking cessation failures, possibly due to the presence of co‐morbid PD and SUDs. There is modest, evidence‐based support for effective treatment interventions for nicotine addiction in PD and SUD. Further research is needed to increase our understanding of nicotine addiction in PD and SUD and develop more effective treatment interventions.

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Crossref · 10.1080/10550490590924728

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169 of 169 references verified0 citation errors · 0 not checkable

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  • A large proportion of smokers report smoking to control symptoms of anxiety and depression, and the rate of smoking in individuals with affective disorders is more than double the general population rate.

    “Similarly, a large proportion of smokers report that they smoke to control symptoms of anxiety and depression (Picciotto et al. 2002), and the rate of smoking in individuals with affective disorders is more than double the rate in the general population (Kalman et al. 2005).”

    From Mechanisms of Nicotine Addiction (2021) · cites this paper as Kalman et al. 2005

    Only the smoking-rate clause is attributed to Kalman et al.; the claim about smoking to control symptoms cites Picciotto et al. The Abstract reports a general-population rate of about 23% and smoking rates of 55–70% in bipolar disorder, supporting a more-than-double comparison for bipolar disorder. But it reports 40–60% for major depression, so more than double is not supported across the full reported range of affective disorders. (LLM, conf=0.85)

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Research works printed but not linked: 5

  1. [4]George TP, Vessicchio JC. Nicotine addiction and schizophrenia. Psychiatric Times. 2001;18(2):39–42. [Google Scholar]
  2. [72]Anda RF, Williamson DF, Escobedo LG, et al. Depression and the dynamics of smoking. JAMA. 1990;264:1541–1545. [PubMed] [Google Scholar]
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  4. [153]George TP, Seyal AA, Dolan SL, Dudas MM, Termine A, Vessicchio JC. Nicotine addiction and schizophrenia: a clinical approach. Primary Psychiatry. 2002;9:48–53. [Google Scholar]
  5. [156]Kalman D, Kahler C, Tirch D, Penk W, Kaschib C, Monti PM. Twelve-week outcomes from an investigation of high dose nicotine patch therapy for heavy smokers with a past history of alcohol dependence. Psychol Addictive Behav. 2004;18:78–82. doi: 10.1037/0893-164X.18.1.78. [DOI] [PubMed] [Google Scholar] · DOI

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Authors
Kalman, D., Morissette, S. B., & George, T. P.
Affiliations
  • Boston University (US)
  • Yale University (US)
Corresponding author
George, Tony P.
Venue
The American Journal on Addictions
Publisher
Wiley
Published
2005-03-04
Volume
14
Issue
2
Pages
106-123
ISSN
  • 1055-0496 (ISSN-L)
  • 1521-0391
OpenAlex
W2109605442
Cited by
594
References
168
Citations by year
2026: 6 · 2025: 16 · 2024: 11 · 2023: 20 · 2022: 26 · 2021: 19 · 2020: 44 · 2019: 20 · 2018: 37 · 2017: 32 · 2016: 38 · 2015: 32 · 2014: 36 · 2013: 43 · 2012: 35
FWCI
2.96
Type
journal article
Language
en
Open access
Locations
  • American Journal on Addictions (publishedVersion)
  • PubMed (publishedVersion)
  • PubMed Central (acceptedVersion)
Funders
National Institute on Drug Abuse (R01-DA-1-4039, R01 DA15757, R29-DA-11713, R01-DA-1-3672, R01DA013672, R01DA015757, R29DA011713, K23DA016376, K02-DA-16611, R01DA014039, K23-DA-16376, K02DA016611)
Topics
  • Health Sciences › Medicine › Physiology › Smoking Behavior and Cessation
  • Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
  • Social Sciences › Psychology › Clinical Psychology › Gambling Behavior and Treatments
Keywords
cigarette smoking, mental illness, substance use disorders, comorbidities, nicotine dependence, smoking cessation, tobacco dependence treatment
MeSH terms
Mental Disorders, Forecasting, Humans, Smoking, Time Factors, United States, Comorbidity, Diagnosis, Dual (Psychiatry), Neurotransmitter Agents, Substance-Related Disorders

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