A randomized clinical trial of acceptance and commitment therapy versus progressive relaxation training for obsessive-compulsive disorder
Open accessAbstract
Objective: Effective treatments for obsessive-compulsive disorder (OCD) exist, but additional treatment options are needed. The effectiveness of 8 sessions of acceptance and commitment therapy (ACT) for adult OCD was compared with progressive relaxation training (PRT). Method: Seventy-nine adults (61 female) diagnosed with OCD (mean age = 37 years; 89 Caucasian) participated in a randomized clinical trial of 8 sessions of ACT or PRT with no in-session exposure. The following assessments were completed at pretreatment, posttreatment, and 3-month follow-up by an assessor who was unaware of treatment conditions: Yale-Brown Obsessive Compulsive Scale (Y-BOCS), Beck Depression Inventory-II, Quality of Life Scale, Acceptance and Action Questionnaire, Thought Action Fusion Scale, and Thought Control Questionnaire. Treatment Evaluation Inventory was completed at posttreatment. Results: ACT produced greater changes at posttreatment and follow-up over PRT on OCD severity (Y-BOCS: ACT pretreatment = 24.22, posttreatment = 12.76, follow-up = 11.79; PRT pretreatment = 25.4, posttreatment = 18.67, follow-up = 16.23) and produced greater change on depression among those reporting at least mild depression before treatment. Clinically significant change in OCD severity occurred more in the ACT condition than PRT (clinical response rates: ACT posttreatment = 46-56, follow-up = 46-66; PRT posttreatment = 13-18, follow-up = 16-18). Quality of life improved in both conditions but was marginally in favor of ACT at posttreatment. Treatment refusal (2.4 ACT, 7.8 PRT) and dropout (9.8 ACT, 13.2 PRT) were low in both conditions. Conclusions: ACT is worth exploring as a treatment for OCD. © 2010 American Psychological Association.
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4 of 51 cited sources checked · 2 supported · 0 flagged · accuracy not yet measured
- Study design and conductcitation
Thirty-eight participants per condition were needed for 80% power to detect the average between-group effect size of d = .66 in the existing ACT literature.
“An n of 38 per condition was required for power of .8 to detect the average between group effect size (d = .66) in the existing ACT literature across all diagnoses (Hayes et al., 2006).”
Quote in the paperSubstantial claim1 of 1 sources checked- cites Hayes et al., 2006 source
The 'Quantitative characterization of the relative strength of ACT outcomes' section (p. 15) reports an average between-condition effect size of d = .66 across the ACT outcome studies it included. Our copy does not state that 38 participants per condition were required for 80% power; that sample-size calculation is not supported by the cited paper. (LLM, conf=0.89)
Experimental — accuracy not yet measured
- Findingown data
More ACT than PRT participants achieved clinically significant OCD severity change across multiple criteria.
“Clinically significant change in OCD severity occurred more in the ACT condition than PRT using multiple criteria (clinical response rates: ACT post=46-56%, follow-up 46-66%; PRT post=13%-18%, follow-up 16-18%).”
Quote in the paperSubstantial claim - Findingown data
Among participants with at least mild depression at baseline, ACT led to larger depression reductions than PRT.
“and produced greater change on depression among those reporting at least mild depression before treatment.”
Quote in the paperNot a substantial claim - Findingown data
Refusal rates were low in both ACT and PRT.
“Finally, treatment refusal (2.4% ACT, 7.8% PRT) and drop-out (9.8% ACT, 13.2% PRT) were low in both conditions.”
Quote in the paperNot a substantial claim - Findingown data
Drop-out rates were low in both ACT and PRT.
“drop-out (9.8% ACT, 13.2% PRT) were low in both conditions.”
Quote in the paperNot a substantial claim
- Findingown data
Seventy percent of the sample (ACT n=27; PRT n=28) met the BDI-II cutoff of 13 for at least mild depression at pre-treatment.
“Seventy percent of the sample (N: ACT = 27; PRT = 28) met that criterion.”
Quote in the paperNot a substantial claim - Findingown data
Both conditions showed significant within-condition improvements in depression from pre to post and pre to follow-up.
“Within condition pre to post and pre to follow-up changes were significant in both conditions: effect sizes were respectively .5 and .93 in the PRT condition and 1.40 and 1.52 in the ACT condition.”
Quote in the paperNot a substantial claim - Findingown data
At posttreatment, ACT was rated significantly more acceptable than PRT (average item score 4.38 vs 3.68).
“At posttreatment, PRT was viewed as an acceptable treatment with an average item score of 3.68 on a 5-point scale. ACT was significantly more acceptable, however (t (65) = 3.57, p = .001, effect size = .89) with an average item score of 4.38.”
Quote in the paperNot a substantial claim - Findingown data
Participants in both ACT and PRT showed significantly improving Y-BOCS slopes over time.
“Participants in both conditions showed significantly improving slopes (ACT: Estimate = -1.22, SE = .13, t (80.90) = -9.40, p < .001, 95% CI: -1.47, -.96; PRT: Estimate = -.79 SE = .13, t (80.40) = -5.88, p < .001, 95% CI: -1.06, -.52)”
Quote in the paperSubstantial claim - Findingown data
After controlling for pre-to-post Y-BOCS change scores, ACT continued to have significantly higher acceptability than PRT.
“ACT continued to have significantly higher levels of acceptability (F (1,64) = 5.25, p = .025, effect size = .57).”
Quote in the paperNot a substantial claim - Premisecitation§ A randomized clinical trial of Acceptance and Commitment Therapy vs. Progressive Relaxation Training for obsessive compulsive disorder
There is no consensus on the psychological processes that explain exposure's benefit.
“but there is no consensus about the psychological processes that account for this benefit (Steketee & Barlow, 2002).”
Quote in the paperSubstantial claim0 of 1 sources checked- cites Steketee & Barlow, 2002
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- Premisecitation§ A randomized clinical trial of Acceptance and Commitment Therapy vs. Progressive Relaxation Training for obsessive compulsive disorder
ERP studies in a recent review averaged 27.4 hours of direct therapist contact plus dozens of hours of client homework.
“The ERP studies covered in a recent review (Abramowitz et al., 2009) averaged 27.4 hours of direct therapist contact in addition to dozens of hours of client homework.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites Abramowitz et al., 2009
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- Interpretationreasoning§ A randomized clinical trial of Acceptance and Commitment Therapy vs. Progressive Relaxation Training for obsessive compulsive disorder
Exposure may work partly by increasing flexible responding in the presence of anxiety, obsessive thoughts, or physical sensations.
“which is consistent with the idea that exposure may work in part by fostering greater flexibility in responding in the presence of previously repertoire narrowing stimuli such as anxiety, obsessive thoughts, or physical sensations.”
Quote in the paperSubstantial claim - Premisecitation§ A randomized clinical trial of Acceptance and Commitment Therapy vs. Progressive Relaxation Training for obsessive compulsive disorder
Component studies of ACT processes in isolation support their usefulness across various contexts.
“Component studies of these processes in isolation (outside of the entire treatment package) support their utility in a variety of contexts (e.g., Levitt et al., 2004; Masuda, Hayes, Sackett, & Twohig, 2004).”
Quote in the paperNot a substantial claim0 of 2 sources checked - Premisecitation§ A randomized clinical trial of Acceptance and Commitment Therapy vs. Progressive Relaxation Training for obsessive compulsive disorder
Clinicians find ERP aversive.
“perhaps in part because clinicians find it aversive (Richard & Gloster, 2007)”
Quote in the paperSubstantial claim0 of 1 sources checked- cites Richard & Gloster, 2007 source
- Premisecitation§ A randomized clinical trial of Acceptance and Commitment Therapy vs. Progressive Relaxation Training for obsessive compulsive disorder
The public rates ERP negatively when its methods are described.
“and the public rates it negatively when the methods are described (Richard & Gloster, 2007).”
Quote in the paperSubstantial claim0 of 1 sources checked- cites Richard & Gloster, 2007 source
- Study design and conductown data
No statistically significant differences between treatment conditions appeared on any demographic factor.
“There were no statistically significant differences between treatment conditions on any of these demographic factors.”
Quote in the paperNot a substantial claim - Premisecitation§ A randomized clinical trial of Acceptance and Commitment Therapy vs. Progressive Relaxation Training for obsessive compulsive disorder
Overt refusal adds an estimated 5% to 22% of participants in ERP.
“overt refusal rates, while often not reported in the literature, represent an additional 5 to 22% of participants (e.g., Foa et al., 2005; McLean et al., 2001).”
Quote in the paperSubstantial claim0 of 2 sources checked - Premisecitation§ A randomized clinical trial of Acceptance and Commitment Therapy vs. Progressive Relaxation Training for obsessive compulsive disorder
Low psychological flexibility is associated with OCD symptom levels in adults and children.
“A lack of psychological flexibility is associated with OCD symptom levels in adults and children (Abramowitz, Lackey, & Wheaton, 2009; Briggs & Price, 2009).”
Quote in the paperSubstantial claim0 of 2 sources checked - Premisecitation§ A randomized clinical trial of Acceptance and Commitment Therapy vs. Progressive Relaxation Training for obsessive compulsive disorder
Evidence supports ACT effectiveness for OCD-spectrum disorders such as skin picking and trichotillomania.
“There is evidence for the effectiveness of ACT in the treatment of OCD-spectrum disorders such as skin picking and trichotillomania (Twohig & Woods, 2004; Twohig, Hayes, & Masuda, 2006a; Woods, Wetterneck, & Flessner, 2006).”
Quote in the paperSubstantial claim0 of 3 sources checked - Premisecitation§ A randomized clinical trial of Acceptance and Commitment Therapy vs. Progressive Relaxation Training for obsessive compulsive disorder
Contemporary animal research indicates extinction works by creating new behaviors and learning rather than unlearning.
“Contemporary animal research suggests that extinction works by fostering new behaviors and new learning rather than unlearning (e.g., Bouton, 2002)”
Quote in the paperSubstantial claim0 of 1 sources checked- cites Bouton, 2002 source
- Premisecitation§ A randomized clinical trial of Acceptance and Commitment Therapy vs. Progressive Relaxation Training for obsessive compulsive disorder
ERP is grossly underutilized.
“ERP is also grossly underutilized (Olatunji, Deacon, & Abramowitz, 2009)”
Quote in the paperSubstantial claim0 of 1 sources checked- cites Olatunji, Deacon, & Abramowitz, 2009 source
- Premisecitation§ A randomized clinical trial of Acceptance and Commitment Therapy vs. Progressive Relaxation Training for obsessive compulsive disorder
In that multiple-baseline study, ACT processes were functionally related to outcomes.
“ACT processes were functionally related to outcomes.”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites Twohig, Hayes, & Masuda, 2006b
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- Premisecitation§ A randomized clinical trial of Acceptance and Commitment Therapy vs. Progressive Relaxation Training for obsessive compulsive disorder
ERP has an approximately 25% drop-out rate.
“ERP suffers from a drop-out rate of approximately 25% (Abramowitz et al., 2009)”
Quote in the paperSubstantial claim0 of 1 sources checked- cites Abramowitz et al., 2009
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- Study design and conductown data
Assessors remained blind to treatment assignment throughout.
“Assessors were supervised by SCH or MPT and were blind to treatment assignment throughout.”
Quote in the paperSubstantial claim - Study design and conductown data
Treatment credibility had the same central tendency and distribution in the two conditions.
“which was non-significant (K-S = .99, N = 71, p = .27), indicating that credibility had the same central tendency and distribution in the two conditions.”
Quote in the paperNot a substantial claim - Study design and conductown data
The number of treatment sessions received did not differ between conditions.
“differences between conditions in the number of treatment sessions received was also examined non-parametrically using a Kolmogorov-Smirnov test, which was non-significant (K-S = .976, N = 79, p = .61).”
Quote in the paperNot a substantial claim - Study design and conductown data
Inter-rater agreement on Y-BOCS scores from pre, post, and follow-up tapes was .90 (95% CI .87, .92), indicating very high agreement.
“Overall agreement was .90 (95% CI: .87, .92) using a twoway mixed intraclass correlation coefficient, suggesting very high agreement on Y-BOCS scores between the original assessor scores and the additional rater scores taken from the tapes.”
Quote in the paperNot a substantial claim - Interpretationcitation
The present study's Y-BOCS reduction (47.3% at post, 51.3% at follow-up) is virtually the same as the average 45.4% reduction in ERP/CT studies.
“On average (weighted by the size of the studies), the studies in the Abramowitz et al. (2009) review produced a 45.4% reduction in the Y-BOCS at post (follow up was not reported), which is virtually the same as the 47.3% reduction (post) and 51.3% (follow-up) reduction seen in the present study.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites Abramowitz et al., 2009
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- Study design and conductcitation
Longitudinal analyses used an intent-to-treat sample containing all randomized participants.
“Longitudinal data were analyzed using Hierarchical Linear Modeling (HLM) and Mixed Model Repeated Measures (MMRM) approaches and an intent-to-treat sample containing all randomized participants (Hedeker & Gibbons, 2006).”
Quote in the paperSubstantial claim0 of 1 sources checked- cites Hedeker & Gibbons, 2006
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- Study design and conductown data
No non-adherent items were observed in any coded ACT sessions.
“No non-adherent items were noted in any of the coded sessions.”
Quote in the paperNot a substantial claim - Premisecitation
Exposure exercises, while clinically useful, are met with resistance by a marked number of professionals and clients.
“This is notable, because exposure exercises, while very useful clinically, are met with resistance by a marked number of professionals and clients (Richard & Gloster, 2007).”
Quote in the paperSubstantial claim0 of 1 sources checked- cites Richard & Gloster, 2007 source
- Premisecitation
Method A for clinically significant change yielded a cutoff score of 14 on the Y-BOCS at post or follow-up.
“Method A for determining the cutoff score for clinically significant change subsequent to a reliable change yielded a cutoff of 14 at post or follow-up, which is the same cutoff as a recent meta-analysis evaluating ERP and ERP/CT for OCD (Fisher & Wells, 2005).”
Quote in the paperSubstantial claim0 of 1 sources checked- cites Fisher & Wells, 2005 source
- Premisecitation
The average therapist contact time for ERP and ERP/CT outcome studies, weighted by study size, was 27.4 hours (range 9-48 hours).
“The average therapist contact time for ERP and ERP/CT outcome studies (weighted by the size of the study) was 27.4 hours (range: 9 – 48 hours) for the studies in the review conducted by Abramowitz et al. (2009).”
Quote in the paperSubstantial claim0 of 1 sources checked- cites Abramowitz et al., 2009
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- Study design and conductown data
ACT therapists' overall adherence to the manual and overall competence were highly rated (M = 4.56, SD = .54 and M = 4.67, SD = .48, respectively).
“Overall adherence to the manual and overall competence were highly rated (M = 4.56, SD = .54 and M = 4.67, SD = .48 respectively).”
Quote in the paperNot a substantial claim - Study design and conductown data
There were no pre-treatment differences between conditions on any outcome measure (p < .05).
“There were no pre-treatment differences (p < .05) on any measure.”
Quote in the paperSubstantial claim - Study design and conductown data
Independent coding of 20% of initial diagnostic interviews yielded 100% agreement on OCD diagnosis and nondiagnosis.
“Twenty percent of the initial diagnostic interviews were independently coded by a second rater; there was 100% agreement on diagnosis and nondiagnosis of OCD.”
Quote in the paperNot a substantial claim - Interpretationcitation
Baseline Y-BOCS scores were very similar between the present study (24.2) and the ERP/CT groups in the Abramowitz et al. (2009) review (23.9).
“The baseline Y-BOCS scores were very similar as well, with a weighted pre-score average of 23.9 in the ERP or ERP/CT groups in the studies in the Abramowitz et al. (2009) review as compared to 24.2 in the present study.”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites Abramowitz et al., 2009
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- Study design and conductown data
PRT sessions had very low frequencies of non-adherent items in acceptance, creative hopelessness/workability, and ERP.
“The frequency of non-adherent items was very low but occurred in the areas of acceptance (M = 1.07, SD = .26), creative hopelessness/workability (M = 1.02, SD = .15) and ERP (M = 1.11, SD = .39).”
Quote in the paperNot a substantial claim - Interpretationcitation
The ACT condition's dropout rate (12.2%) appears below rates expected from recent reviews of ERP and ERP/CT.
“Thus 5 of 41 ACT participants (12.2%) were categorized as actively or passively declining or dropping out of treatment, which appears to be below the rates expected from recent reviews of ERP and ERP/CT (e.g., Abramowitz et al., 2009).”
Quote in the paperSubstantial claim0 of 1 sources checked- cites Abramowitz et al., 2009
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- Interpretationown data
The ACT model appears broadly applicable to an OCD population.
“All of this suggests that an ACT model appears to be broadly applicable to an OCD population.”
Quote in the paperSubstantial claim - Study design and conductown data
Follow-up was limited to three months.
“Follow-up was only three months due to the preliminary nature of this study, but six-month to two-year follow-up is preferable.”
Quote in the paperNot a substantial claim - Interpretationown data
ACT can lead to meaningful clinical outcomes without necessarily using traditional exposure procedures.
“It appears that ACT can lead to meaningful clinical outcomes without necessarily using traditional exposure procedures.”
Quote in the paperSubstantial claim
- May combine two claims. 56
- Classified as probably not a substantial claim. 31
May combine two claims.
Premisecitation§ A randomized clinical trial of Acceptance and Commitment Therapy vs. Progressive Relaxation Training for obsessive compulsive disorderStudies show ACT affects psychological flexibility and yields positive outcomes when flexibility increases.
“A number of studies show that ACT impacts psychological flexibility and produces positive outcomes when psychological flexibility increases (e.g., Hayes et al., 2006).”
Quote in the paperSubstantial claim1 of 1 sources checked- cites Hayes et al., 2006 source
Probably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
PremisecitationThe AAQ has good convergent and discriminant validity and four-month test-retest reliability of r = .64.
“The Acceptance and Action Questionnaire has good convergent and discriminant validity and test-retest reliability after a four month period was r =.64 (Hayes et al., 2004; Hayes et al., 2006).”
Quote in the paperNot a substantial claim1 of 2 sources checked- cites Hayes et al., 2004 source
- cites Hayes et al., 2006 source
In Research on ACT (p. 10), the paper says that two validated AAQ versions have adequate convergent validity. Our copy does not report discriminant validity or a four-month test–retest reliability of r = .64; searches for those terms and the coefficient did not locate either result. (LLM, conf=0.87)
Experimental — accuracy not yet measured
Probably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
PremisecitationThe TAFS total score has three-month test-retest reliability of r = .52 and shows construct validity with other measures.
“Three month test-retest reliability for the total score were r =.52, and it shows construct validity with other measures (Rassin, Merckelbach, Muris, & Schmidt, 2001).”
Quote in the paperNot a substantial claim1 of 1 sources checked- cites Rassin, Merckelbach, Muris, & Schmidt, 2001 source
May combine two claims.
Findingown dataACT led to larger reductions in OCD severity than PRT at posttreatment and at three-month follow-up.
“ACT produced greater changes at posttreatment and follow-up over PRT on OCD severity (Y-BOCS: ACT pre=24.22, post=12.76, follow-up=11.79; PRT pre=25.4, post=18.67, follow-up=16.23)”
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataQuality of life improved in both groups, with a marginal advantage for ACT at posttreatment.
“Quality of life improved in both conditions but was marginally in favor of ACT at post.”
Quote in the paperNot a substantial claimMay combine two claims.
Findingown dataFor depression, there was no significant effect of condition, but significant effects of time and condition-by-time interaction.
“revealed a non-significant effect for treatment condition, F (1, 55.32) = .35, p = .56, but significant effects for time, F (2, 69.63) = 44.14, p < .001, and the interaction between condition and time, F (2, 69.63) = 5.61, p = .006.”
Quote in the paperNot a substantial claimMay combine two claims.
Findingown dataFor the Thought Action Fusion Scale moral subscale, there was no significant effect of condition, a significant effect of time, and a significant condition-by-time interaction.
“revealed a non-significant effect for treatment condition, F (1, 76.34) = 1.25, p = .27, and a significant effect for time, F (1, 71.72) = 16.32, p < .001, and the interaction of condition and time, F (1, 71.72) = 11.39, p = .001, end point outcome effect size = .73.”
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataNumber of treatment sessions was not related to follow-up decreases in Y-BOCS in either condition, but was correlated with post decreases in Y-BOCS in the ACT condition.
“The number of treatment sessions was not related to follow-up decreases in the Y-BOCS in either the PRT condition (Spearman's rho (31) = -.12, p = .54), or the ACT condition (Spearman's rho (33) = -.15, p = .41). Post result were similar for the PRT condition, but the number of treatment sessions was correlated with post decreases in the Y-BOCS in the ACT condition (Spearman's rho (33) = -.30, p =”
Quote in the paperNot a substantial claimMay combine two claims.
Findingown dataACT participants showed an improving slope on the TAF likelihood subscale, while PRT participants showed a trend toward improvement.
“ACT participants showed an improving slope (ACT: Estimate = -.41, SE = .09, t (135.54) = -4.46, p < .001) while PRT participants showed a trend for one (PRT: Estimate = -.17, SE = .10, t (136.00) = -1.75, p = .082).”
Quote in the paperNot a substantial claimMay combine two claims.
Findingown dataSeventy-five percent of ACT participants rated the treatment with an average score of 4 or better, and 25% gave the highest acceptability score.
“Seventy-five percent of the ACT participants rated the treatment with an average score of 4 or better and 25% rated it with the highest acceptability score.”
Quote in the paperNot a substantial claimMay combine two claims.
Findingown dataFor the Thought Control Questionnaire, there was an approaching significant effect of condition, a significant effect of time, and a significant condition-by-time interaction.
“revealed an approaching significant effect for treatment condition, F (1, 77.28) = 3.18, p = .079, and a significant effect for time, F (2, 70.43) = 17.88, p < .001, and the interaction of condition and time, F (2, 70.43) = 5.11, p = .008.”
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataQuality of life did not differ between conditions at follow-up, but there was a trend favoring ACT at post.
“There was no difference in improvement between conditions at follow-up (Estimated Mdiff = .18, SE = 3.14, t (63.49) = .06, p = .96, 95% CI: -6.10, 6.46, effect size = .01) but there was a trend toward a difference at post (Estimated Mdiff = 5.46, SE = 2.78, t (70.22) = 1.96, p = .054, 95% CI: -.09, 11.00, effect size = .47).”
Quote in the paperNot a substantial claimMay combine two claims.
Findingown dataACT produced a significantly greater rate of Y-BOCS improvement than PRT, with a large end-point effect size (.84).
“but the ACT condition produced a large and significant difference in rate of improvement (Estimate = .42, SE = .19, t (80.64) = 2.27, p = .026, 95% CI: .05, .80, end point outcome effect size = .84).”
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataFor the Acceptance and Action Questionnaire, there were significant effects of condition, time, and their interaction.
“revealed a significant effect for treatment condition, F (1, 69.78) = 7.30, p = .009, time, F (2, 66.36) = 22.14, p < .001, and their interaction, F (2, 66.35) = 5.60, p = .006.”
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataTreatment credibility was not related to follow-up decreases in Y-BOCS in either condition, and post results showed the same pattern.
“Credibility was not related to follow-up decreases in the Y-BOCS in either the PRT (Spearman's rho (31) = -.04, p = .83) or the ACT condition (Spearman's rho (30) = .07, p = .70). Post results showed the same pattern.”
Quote in the paperNot a substantial claimMay combine two claims.
Findingown dataFor the Y-BOCS, there was a significant effect of time, no significant effect of condition, and a significant condition-by-time interaction.
“There was a significant effect for time F (1, 80.64) = 115.54, p < .001, no effect for condition, F (1, 92.98) = 1.16, p = .28, and a significant interaction between condition and time, F (1, 80.64) = 5.15, p = .026.”
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataACT improved significantly more on the TCQ than PRT from pre to post, with a trend toward greater improvement from pre to follow-up.
“The interaction occurred because ACT participants improved significantly more from pre to post than did PRT participants (Estimated Mdiff = -6.67, SE = 2.12, t (72.51) = -3.14, p = .002, 95% CI: -10.90, -2.43, effect size = .75). There was a trend toward a difference from pre to follow-up (Estimated Mdiff = -4.56, SE = 2.59, t (75.70) = 1.77, p = .082, 95% CI: -9.72, .59, effect size = .42).”
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataUsing imputed values from person-specific growth curves, ACT had significantly more clinically significant responders than PRT at post (23/41 vs 7/38) and follow-up (27/41 vs 6/38).
“Using these values the two conditions again differed at post (ACT: 23 of 41; PRT: 7 of 38; χ2 (1) = 10.30, p < .002, two-tailed, effect size = .77) and follow-up (ACT: 27 of 41; PRT: 6 of 38; χ2 (1) = 18.24, p < .001, two-tailed, effect size = 1.10).”
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataBoth conditions showed significant within-condition improvements on the AAQ from pre to post and pre to follow-up.
“Within condition pre to post and pre to follow-up changes were significant: effect sizes were respectively .47 and .64 in the PRT condition and 1.06 and .86 in the ACT condition.”
Quote in the paperNot a substantial claimMay combine two claims.
Findingown dataFor quality of life, there was no significant effect of condition, a significant effect of time, and a trend toward a condition-by-time interaction.
“revealed a non-significant effect for condition, F (1, 66.53) = 2.41, p = .126, but a significant effect for time, F (2, 64.62) = 11.44, p < .001, and trend toward an interaction between condition and time, F (2, 64.62) = 2.99, p = .057.”
Quote in the paperNot a substantial claimMay combine two claims.
Findingown dataACT participants showed an improving slope on the TAF moral subscale, while PRT participants did not.
“ACT participants showed an improving slope (ACT: Estimate = -.86, SE = .16, t (71.93) = -5.32, p < .001) but PRT participants did not (PRT: Estimate = -.07, SE = .17, t (71.52) = -.46, p = .65).”
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataACT had significantly more participants showing clinically significant improvement than PRT at post (19/41 vs 5/38) and follow-up (19/41 vs 7/38).
“The two conditions differed at post (ACT: 19 of 41; PRT: 5 of 38; χ2 (1) = 10.27, p =.002, two-tailed, effect size = .77) and follow-up (ACT: 19 of 41; PRT: 7 of 38; χ2 (1) = 6.96, p < .009, two-tailed, effect size = .62).”
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataWithin-condition changes on the TCQ were significant in ACT at both pre-post and pre-follow-up, and in PRT at pre-follow-up but not pre-post.
“Within condition pre to post and pre to follow-up changes were .31 (p = .071) and .40 (p = .022) in the PRT condition and .80 (p < .001) and .81 (p < .001) in the ACT condition.”
Quote in the paperNot a substantial claimMay combine two claims.
Findingown dataFor the TAF likelihood subscale, there was no significant effect of condition, a significant effect of time, and a trend toward a condition-by-time interaction.
“revealed a non-significant effect for treatment condition, F (1, 117.43) = 1.41, p = .24, and a significant effect for time, F (1, 135.78) = 18.94, p < .001, and a trend toward an interaction of condition and time, F (1, 135.78) = 3.33, p = .07, end point outcome effect size = .31.”
Quote in the paperNot a substantial claimMay combine two claims.
Findingown dataACT improved significantly more on the AAQ than PRT from pre to post, but the conditions were equivalent from pre to follow-up.
“The interaction occurred because ACT participants improved significantly more from pre to post than did PRT participants (Estimated Mdiff = -7.73, SE = 3.09, t (70.22) = -2.50, p = .015, 95% CI: -13.90, -1.957, effect size = .59), but the two conditions were equivalent from pre to follow-up (Estimated Mdiff = -3.11, SE = 3.40, t (67.89) = -.92, p = .36, 95% CI: -9.89, 3.66, effect size = .22).”
Quote in the paperNot a substantial claimMay combine two claims.
Premisecitation§ A randomized clinical trial of Acceptance and Commitment Therapy vs. Progressive Relaxation Training for obsessive compulsive disorderERP and ERP with cognitive procedures are recognized as well-supported treatments that produce clinically significant benefit for most patients.
“Exposure with ritual prevention (ERP) and ERP with cognitive procedures (ERP/CT) are recognized as well-supported treatment methods that have a clinically significant impact on the majority of patients (Abramowitz, Taylor, & MacKay, 2009; Fisher & Wells, 2005)”
Quote in the paperSubstantial claim0 of 2 sources checked- cites Abramowitz, Taylor, & MacKay, 2009
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- cites Fisher & Wells, 2005 source
May combine two claims.
Premisecitation§ A randomized clinical trial of Acceptance and Commitment Therapy vs. Progressive Relaxation Training for obsessive compulsive disorderIn that multiple-baseline study, OCD severity shifted from clinical to nonclinical range, compulsions neared zero by treatment end, and gains held at follow-up.
“OCD severity scores moved from the clinical to the nonclinical range and results showed near zero levels of compulsions by the end of treatment, with results maintained at follow-up.”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites Twohig, Hayes, & Masuda, 2006b
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
Classified as probably not a substantial claim. May combine two claims.
Study design and conductown dataTreatment assignment used a random sequence of concealed slips opened after consent by someone other than the assessors.
“Treatment assignment was made by a random sequence of concealed slips, opened following the agreement to participate by a person other than the assessors (41 ACT, 38 PRT).”
Quote in the paperSubstantial claimMay combine two claims.
Premisecitation§ A randomized clinical trial of Acceptance and Commitment Therapy vs. Progressive Relaxation Training for obsessive compulsive disorderOCD is often complex, with most patients having comorbid mood, anxiety, or substance use disorders.
“OCD tends to be a complex disorder with the majority of patients also having comorbid unipolar mood disorders, other anxiety disorders, or substance use disorders (Abramowitz et al., 2009)”
Quote in the paperSubstantial claim0 of 1 sources checked- cites Abramowitz et al., 2009
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
May combine two claims.
Premisereasoning§ A randomized clinical trial of Acceptance and Commitment Therapy vs. Progressive Relaxation Training for obsessive compulsive disorderERP and ERP/CT are intensive treatments.
“ERP and ERP/CT are intensive treatments.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Study design and conductown dataNo participant openly refused after random assignment.
“No participants overtly refused participation after random assignment.”
Quote in the paperNot a substantial claimMay combine two claims.
Premisecitation§ A randomized clinical trial of Acceptance and Commitment Therapy vs. Progressive Relaxation Training for obsessive compulsive disorderIn a multiple-baseline study of four adults with OCD, eight weekly one-hour ACT sessions without in-session exposure significantly improved OCD severity, depression, and anxiety.
“In a multiple baseline with four adults diagnosed with OCD (Twohig, Hayes, & Masuda, 2006b), eight weekly one-hour sessions of ACT without in-session exposure had a significant impact on OCD severity, depression, and anxiety.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites Twohig, Hayes, & Masuda, 2006b
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
Classified as probably not a substantial claim.
Premisecitation§ A randomized clinical trial of Acceptance and Commitment Therapy vs. Progressive Relaxation Training for obsessive compulsive disorderExposure to a feared situation with sustained stay is generally therapeutic.
“Merely the act of exposing oneself to a feared situation and staying in that situation for a meaningful period of time is generally therapeutic (Abramowitz, 1996)”
Quote in the paperSubstantial claim0 of 1 sources checked- cites Abramowitz, 1996 source
Classified as probably not a substantial claim.
Study design and conductnone givenAll randomized participants were included in the main analyses.
“All randomized participants were included in the main analyses.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Study design and conductown dataIn this trial, Treatment Evaluation Inventory-Short Form alpha was .94.
“In the present trial α =.94.”
Quote in the paperNot a substantial claimMay combine two claims.
Study design and conductown dataThe ACT condition did not include in-session exposure exercises, and participants were not asked to approach feared stimuli or stay in their presence; treatment integrity ratings indicated that suggesting such activities outside session also never occurred.
“ACT, as conducted in this trial, did not include in-session exposure exercises. ACT participants were not asked during treatment to approach a feared stimulus, including primary obsessions, and stay in its presence for a period of time. Based on treatment integrity ratings, suggesting that engaging in such activities would be helpful outside of session also never occurred.”
Quote in the paperSubstantial claimMay combine two claims.
Study design and conductown dataInter-rater reliability for ACT treatment integrity ratings was .94 (95% CI .90, .96) between master rater and rater 1 and .80 (95% CI .63, .90) between master rater and rater 2.
“Inter-rater reliability across all domains assessed for integrity (described in detail below) was .94 (95% CI: .90, .96) between the master rater and rater 1 and .80 (95% CI: .63, .90) between the master rater and rater 2.”
Quote in the paperNot a substantial claimMay combine two claims.
Study design and conductown dataFisher's exact tests found no significant between-condition differences in co-occurring disorders or OCD subtypes, except ACT had more symmetry/exactness concerns (p = .03).
“Based on a Fisher's exact test none of these differences in co-occurring disorders or sub-types of OCD were significantly different (p < .05) between conditions except that those in the ACT condition had more concern with symmetry/exactness (p = .03).”
Quote in the paperNot a substantial claimMay combine two claims.
Study design and conductown dataThe clinical significance analysis scored all refusals, dropouts, and missing data as unimproved and included them in the denominator, providing a full intent-to-treat analysis.
“All refusals, dropouts, or missing data were scored as unimproved and included in the denominator, providing a full intent to treat analysis.”
Quote in the paperSubstantial claimMay combine two claims.
Study design and conductown dataMinimal participation or passive dropout was low: 4 of 41 ACT participants (9.8%) and 5 PRT participants (13.2%) attended only 1 or 2 sessions.
“The rates for minimal participation or passive dropout were similarly low; 4 of 41 (9.8%) ACT participants and 5 PRT participants (13.2%) attended only 1 or 2 sessions.”
Quote in the paperNot a substantial claimMay combine two claims.
InterpretationcitationThe present study's duration is below the range found in the Abramowitz et al. (2009) review and represents 29-31% of the average duration of comparable protocols.
“The present study is below the range of durations found in that review (or an earlier review by Fisher and Wells, 2005) and represents 29-31% of the average duration of comparable protocols.”
Quote in the paperSubstantial claim0 of 2 sources checked- cites Abramowitz et al., 2009
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- cites Fisher and Wells, 2005 source
Probably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
PremisecitationThe TCQ is widely used for OCD and anxiety-related disorders and has been shown to change with cognitive behavioral interventions.
“This is a widely used measure of this construct for obsessive compulsive and anxiety related disorders and has been shown to change as a result of cognitive behavioral interventions (e.g., Reynolds & Wells, 1999).”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites Reynolds & Wells, 1999 source
May combine two claims.
InterpretationreasoningThe absence of exposure exercises may partly account for the good treatment acceptability results, and the present approach may offer an alternative for OCD when exposure has failed or is declined.
“The absence of these exercises may in part account for the good results seen in treatment acceptability, and thus the present approach may offer an alternative approach to the treatment of OCD when exposure has failed or is declined.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
PremisecitationThe Y-BOCS has good interrater reliability for total scores (rs .80-.97) and two-week test-retest reliability (.81-.97).
“The Y-BOCS has good interrater reliability for the total score (rs between .80 and .97) and two-week test-retest reliability between .81 and .97.”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites Goodman et al., 1989
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
May combine two claims.
Study design and conductown dataTreatment refusal was very low: 1 of 41 ACT participants (2.4%) and 3 of 38 PRT participants (7.8%) did not attend Session 1.
“In the present study no participants overtly refused treatment assignment; 1 participant of the 41 the ACT condition (2.4%) and 3 of the 38 in the PRT condition (7.8%) did not attend Session 1, indicating very low passive treatment refusal.”
Quote in the paperNot a substantial claimMay combine two claims.
Study design and conductown dataEntering treatment credibility, acceptability, and number of sessions as covariates did not change the primary outcomes; results generally became fractionally stronger in favor of ACT.
“Entering treatment credibility, acceptability, and number of treatment sessions as covariates did not change the primary outcomes reported here (results generally became fractionally stronger in favor of ACT).”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
PremisecitationThe BDI-II has shown good internal consistency and high test-retest reliability.
“The BDI-II has shown good internal consistency, and high test-retest reliability.”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites Beck, 1996
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
May combine two claims.
Study design and conductown dataPRT therapists' overall adherence to the manual and overall competence were highly rated (M = 4.60, SD = .73 and M = 4.65, SD = .57, respectively).
“On a five-point scale, PRT therapists’ overall adherence to the manual and overall competence were highly rated (M = 4.60, SD = .73 and M = 4.65, SD = .57 respectively).”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Study design and conductown dataIn this trial, QOLS alpha was .89.
“In the present trial α =.89.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Study design and conductown dataIn this trial, AAQ alpha was .74.
“In the present trial α =.74.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
Study design and conductown dataIn this trial, TAFS alpha was .92, moral subscale alpha .91, and likelihood subscale alpha .95.
“In the present trial α =.92; TAF moral subscale α = .91; TAF likelihood subscale α = .95.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
PremisecitationThe QOLS has shown internal consistency (alpha .89-.92) and good temporal stability (rs .78-.84 over three weeks).
“It has been found to be internally consistent (αs between .89 and .92), with good temporal stability (rs between .78 to .84 over three weeks) (Burckhardt et al., 1989).”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites Burckhardt et al., 1989 source
Probably not a substantial claim: may not pass S3 (load-bearing).
Study design and conductown dataIn this trial, BDI-II alpha was .90.
“In the present trial α =.90.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
PremisecitationThe TCQ has good test-retest reliability (r = .83).
“Test-retest reliability is good (r =.83).”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites Wells & Davies, 1994 source
Probably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
PremisecitationKappa above .70 has been found for most clinical disorders, and SCID validity is generally noted from its similarity to the DSM.
“In general, Kappa > .70 has been found for most clinical disorders and validity is generally noted based on the SCID's similarity to the DSM (Summerfeldt & Antony, 2004).”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites Summerfeldt & Antony, 2004
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
May combine two claims.
Interpretationown dataThe tested ACT for OCD protocol is notable for its short duration (8 one-hour sessions) and for the efficiency of results per unit of effort.
“The ACT for OCD protocol that was tested in this investigation is perhaps most notable for its short duration (8 one-hour sessions), and thus, for the efficiency of the results produced on a per unit of effort basis.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Study design and conductown dataIn this trial, Y-BOCS Cronbach's alpha at pretreatment was .79.
“In the present trial Cronbach's α at pre was .79.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Study design and conductown dataIn this trial, TCQ alpha was .82.
“In the present trial α =.82.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
PremisecitationThe SCID is considered the gold standard for psychiatric diagnosis and has shown largely consistent diagnostic reliability across studies.
“The SCID is considered the gold standard in psychiatric diagnosis and has shown largely consistent diagnostic reliability across studies (Segal, Hersen, & Van Hasselt, 1994).”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites Segal, Hersen, & Van Hasselt, 1994 source
May combine two claims.
Study design and conductown dataInter-rater reliability for PRT treatment integrity ratings was .98 (95% CI .93, .98) between master rater and rater 1 and .95 (95% CI .82, .96) with rater 2.
“Inter-rater reliability across all domains assessed for integrity (described in detail below) between the master rater and rater 1 was .98 (95% CI: .93, .98), and rater 2 was .95 (95% CI: .82, .96).”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Study design and conductcitationThe PRT protocol was briefer than suggested by its authors.
“Also, the PRT protocol was briefer than suggested by the authors (Bernstein et al., 2000).”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites Bernstein et al., 2000
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
Probably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
PremisecitationACT researchers have argued that ACT is an exposure-based approach, and doing exposure procedurally within ACT is generally suggested for anxiety disorders.
“ACT researchers have long argued that ACT is an exposure based approach (see Hayes, 1987) and doing exposure in a procedural sense within an ACT approach is generally suggested for anxiety disorders (Eifert & Forsyth, 2005), even though it was eschewed for strategic reasons in the present study.”
Quote in the paperNot a substantial claim0 of 2 sources checked- cites Hayes, 1987
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- cites Eifert & Forsyth, 2005
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
Classified as probably not a substantial claim.
Premisenone givenIn an ACT model, repertoire-narrowing stimuli include not only external events but also fused thoughts, avoided emotions, and experiences that induce inflexible attentional processes.
“In an ACT model, these repertoire narrowing stimuli are not just external events, but also fused thoughts, avoided emotions, experiences that induce inflexible attentional processes, and so on.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
PremisecitationPreliminary data indicate that ACT methods can make exposure more acceptable and less aversive in individuals with panic disorder.
“There are some preliminary data that ACT methods can make exposure more acceptable and less aversive in individuals diagnosed with panic disorder (Levitt et al., 2004), and the same might be true with OCD.”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites Levitt et al., 2004 source
Probably not a substantial claim: may not pass S2 (checkable).
InterpretationreasoningThe absence of in-session exposure in a procedural sense does not mean that exposure in a broader sense was unimportant to the results.
“The absence of in-session exposure in a procedural sense does not mean that exposure in a broader sense was unimportant to the results seen.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S2 (checkable), S3 (load-bearing).
Study design and conductreasoningThe ACT and PRT conditions could have been matched better if PRT participants had been asked to use relaxation in response to obsessions, as ACT participants used ACT strategies when obsessions were present.
“Also, the ACT and PRT conditions could have been matched better if the participants in the PRT condition were asked to use relaxation in response to obsessions because ACT participants used ACT strategies when obsessions were present.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
Study design and conductnone givenAssessors were blinded, but penetration of the blind was not formally assessed.
“Assessors were blinded, but penetration of the blind was not formally assessed.”
Quote in the paperNot a substantial claimMay combine two claims.
Study design and conductown dataThe sample was not ethnically diverse (88.6% Caucasian), so extension of results in this area should be done with caution.
“It should also be noted that the sample drawn for this investigation was not ethnically diverse (88.6% Caucasian), thus, extension of the present results in this area should be done with caution.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S2 (checkable). May combine two claims.
InterpretationreasoningACT looks promising as a treatment for OCD, but much more work is needed.
“ACT looks promising as a treatment for OCD, but clearly much more work is needed to develop this approach.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
Interpretationown dataThe values-based actions in this study might be little more than a procedural variant of exposure, but if so, it appears to be one with very high acceptability.
“This might be little more than a procedural variant of exposure–if so, it appears to be one with a very high level of acceptability.”
Quote in the paperNot a substantial claimClassified as probably not a substantial claim.
PremisecitationACT theory views exposure as organized, values-based contact with previously repertoire-narrowing stimuli to produce greater psychological flexibility.
“At the level of process, ACT theory views exposure as organized, values-based contact with previously repertoire narrowing stimuli for the purpose of producing greater psychological flexibility (Hayes, Strosahl, & Wilson, in press).”
Quote in the paperSubstantial claim0 of 1 sources checked- cites Hayes, Strosahl, & Wilson, in press
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
May combine two claims.
Study design and conductnone givenThe quality of life measure was entirely self-report, and the main outcome measure, while externally rated, focused entirely on symptom severity.
“The quality of life measure was entirely self-report and the main outcome measure, while externally rated, was entirely focused on symptom severity.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Study design and conductreasoningBecause the same assessor was used for all participants at all time points, participants were not blind to the timing of assessments.
“Additionally, because the same assessor was used for all participants at all time points to maintain consistency in assessments, the participants were not blind to the timing of assessments.”
Quote in the paperNot a substantial claim
The paper relies on this without support.
At the time of the study, no randomized controlled trial of ACT for OCD had been published.
“To date, however, there is no published randomized controlled trial on ACT for OCD.”
The paper relies on this without support.
For many participants, compulsions interfered with living according to one or more valued domains.
“For many participants, engaging in compulsions had been a barrier to living in accordance with one or more valued domains.”
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Case studies, multiple-baseline studies, and a single randomized trial provide early evidence that ACT is effective for anxiety disorders.
“Case studies, multiple-baseline treatment studies and a single randomized clinical trial provide nascent evidence that ACT is an effective treatment for anxiety disorders”
From Randomized clinical trial of cognitive behavioral therapy (CBT) versus acceptance and commitment therapy (ACT) for mixed anxiety disorders (2012) · cites this paper as Twohig et al., 2010
The Introduction (page not provided) describes a prior multiple-baseline study in four adults with OCD, and the Discussion (page not provided) reports that this randomized trial found greater improvement in OCD symptoms with ACT than with progressive relaxation training. The paper does not establish the claimed case-study evidence or effectiveness across anxiety disorders generally; its trial findings concern OCD. (LLM, conf=0.86)
Experimental — accuracy not yet measuredSome data suggest that conventional CBT and ABBT produce comparable decreases in EA.
“On the other hand, there is some evidence that traditional CBT is as effective as ABBT in reducing EA (Arch et al., 2012b; Twohig et al., 2010), which suggests that EA could be considered as a common mechanism.”
From Reductions in experiential avoidance as a mediator of change in symptom outcome and quality of life in acceptance-based behavior therapy and applied relaxation for generalized anxiety disorder (2016) · cites this paper as Twohig et al., 2010
The Method’s Process Results report significant improvement on the Acceptance and Action Questionnaire in both groups and no significant difference between them from pretreatment to follow-up. But this trial compared ACT with progressive relaxation training, not traditional CBT; ACT also improved significantly more than relaxation training immediately after treatment. It therefore does not establish comparable reductions in experiential avoidance with CBT and ABBT. (LLM, conf=0.84)
Experimental — accuracy not yet measuredAcceptance and commitment therapy is effective for treating OCD, as are mindfulness-based interventions.
“ACT, of which psychological flexibility/inflexibility is a process of change, is effective for treating OCD, as are mindfulness-based interventions (Bluett et al., 2014;Chien et al., 2022;Twohig et al., 2010).”
From A pilot study of experiencing racial microaggressions, obsessive-compulsive symptoms, and the role of psychological flexibility (2023) · cites this paper as Twohig et al., 2010
The Discussion reports greater improvement in OCD symptoms with ACT than with progressive relaxation training, and the paper describes psychological flexibility as an ACT process. The Method section says the ACT protocol included mindfulness exercises, but the study did not evaluate mindfulness-based interventions as separate treatments for OCD, so it does not support that part of the sentence. (LLM, conf=0.87)
Experimental — accuracy not yet measuredGreater increases in decentering were found across ACT relative to CBT or relaxation training, but findings are equivocal with others reporting non-significant effects of intervention-type on decentering.
“Greater increases in decentering were found across ACT relative to CBT73,89 or relaxation training80.”
From Decentering as a core component in the psychological treatment and prevention of youth anxiety and depression: a narrative review and insight report (2021) · cites this paper as [80]
The Method’s Process Results report greater pre-to-post improvement with ACT than with progressive relaxation training on psychological flexibility and thought-control measures. The ACT protocol describes exercises resembling decentering, but the paper does not report a decentering measure or a comparative increase in decentering itself. This verdict concerns the relaxation-training comparison; the cited paper did not compare ACT with CBT. (LLM, conf=0.77)
Experimental — accuracy not yet measuredThe current intervention is founded on Acceptance and Commitment Therapy (ACT), which has demonstrated efficacy for treating anxiety.
“The current intervention is founded on a theory-driven, evidence-based behavioral approach, Acceptance and Commitment Therapy (ACT), with demonstrated efficacy for treating anxiety [49–53].”
From A randomized controlled trial of a group acceptance-based intervention for cancer survivors experiencing anxiety at re-entry ('Valued Living'): Study protocol (2019) · cites this paper as [51]
The Introduction describes ACT as a theory-driven approach to anxiety, and the Primary Outcome: Y-BOCS section reports significantly greater improvement with ACT than with progressive relaxation training. But this trial studied adults with obsessive-compulsive disorder; it does not establish efficacy for treating anxiety broadly. Page numbers are unavailable in our copy. (LLM, conf=0.85)
Experimental — accuracy not yet measured
According to RFT, psychopathology is primarily the result of the verbal context through which one experiences thoughts and feelings, rather than the content, form, or frequency of the thoughts and feelings themselves.
“According to RFT, psychopathology is primarily the result of the verbal context through which one experiences thoughts and feelings, rather than the result of the content, form, or frequency of the thoughts and feelings themselves (Twohig, Plumb, Mukherjee, & Hayes, 2010).”
From A Comparison of Two Brief Interventions for Obsessional Thoughts: Exposure and Acceptance. (2013) · cites this paper as Twohig et al., 2010
The introduction describes ACT as changing how people relate to thoughts and feelings rather than focusing on their content. The Method (‘ACT for OCD’) likewise emphasizes changing the function of obsessions rather than reducing them. However, the paper does not identify this as an RFT account or claim that psychopathology generally results primarily from verbal context rather than the content, form, or frequency of thoughts and feelings. Page numbers were not available in our copy. (LLM, conf=0.84)
Experimental — accuracy not yet measuredACT led to significantly greater reductions in OCD symptoms than PMR.
“ACT led to significantly greater reductions in OCD symptoms than PMR”
From An update on the efficacy of psychological treatments for obsessive-compulsive disorder in adults (2013) · cites this paper as Twohig et al., 2010
At end of treatment, 46% of ACT patients achieved clinically significant change compared to 13% in PMR.
“at the end of treatment 46% of the ACT patients had achieved clinically significant change compared to 13% in PMR”
From An update on the efficacy of psychological treatments for obsessive-compulsive disorder in adults (2013) · cites this paper as Twohig et al., 2010
ACT may be designated as possibly efficacious in treatment of OCD.
“ACT may therefore be designated as possibly efficacious in the treatment of OCD.”
From An update on the efficacy of psychological treatments for obsessive-compulsive disorder in adults (2013) · cites this paper as Twohig et al., 2010
An ACT model without behavioral exposure was effective for obsessive-compulsive disorder.
“For example, Twohig, Hayes, and Masuda (2006) and Twohig et al. (2010) found that the elements of an ACT model minus behavioral exposure were effective for obsessive-compulsive disorder.”
From Acceptance and Commitment Therapy and Contextual Behavioral Science: Examining the Progress of a Distinctive Model of Behavioral and Cognitive Therapy (2013) · cites this paper as Twohig et al. (2010)
In Twohig et al. (2010), ACT had greater pre-post EA reductions than PRT, but groups were equivalent at 3-month follow-up.
“ACT participants reported significantly greater reductions in EA from pre-treatment to post-treatment compared with PRT participants, however the two groups were equivalent when examining reductions in EA from pre-treatment to 3-month follow-up.”
From Reductions in experiential avoidance as a mediator of change in symptom outcome and quality of life in acceptance-based behavior therapy and applied relaxation for generalized anxiety disorder (2016) · cites this paper as Twohig et al., 2010
These novel clinical findings align with recent literature suggesting that ACT is an effective treatment for OCD and point to willingness to experience obsessions and anxiety as a potential mechanism of change during exposure therapy.
“These novel clinical findings align with recent literature suggesting that ACT is an effective treatment for OCD (Twohig et al., 2010) and point to willingness to experience obsessions and anxiety as a potential mechanism of change during exposure therapy.”
From How willing are you? Willingness as a predictor of change during treatment of adults with obsessive–compulsive disorder (2017) · cites this paper as Twohig et al., 2010
Twohig et al. (2010) found that ACT produced favorable outcomes on a number of post-treatment measures of OCD, when compared with progressive RT.
“Twohig et al. (2010), for example, found that ACT produced favorable outcomes on a number post-treatment measures of OCD, when compared progressive RT.”
From How Exactly Do I “Let Go”? The Potential of Using ACT to Overcome the Relaxation Paradox (2014) · cites this paper as Twohig et al. (2010)
Pour le TOC, les données sont à ce jour limitées à un essai randomisé contrôlé comparant l'ACT à la relaxation musculaire progressive.
“Pour le TOC, les données sont à ce jour limitées à un essai randomisé contrôlé comparant l’ACT à la relaxation musculaire progressive (Twohig, Hayes, Plumb, Pruitt, Collins et coll. 2010)”
From Les thérapies de troisième vague dans le traitement du trouble obsessionnel-compulsif: Application de la thérapie d’acceptation et d’engagement (2014) · cites this paper as Twohig, Hayes, Plumb, Pruitt, Collins et coll. 2010
Dans cet essai randomisé contrôlé, l'ACT s'est montré supérieur à la relaxation progressive, avec 50% versus 15% de réponse et un effet de taille de 0,84 pour la condition ACT.
“dans lequel l’ACT s’est montré supérieur à la relaxation progressive (50% vs 15% de réponse et un effet de taille de 0,84 pour la condition ACT)”
From Les thérapies de troisième vague dans le traitement du trouble obsessionnel-compulsif: Application de la thérapie d’acceptation et d’engagement (2014) · cites this paper as Twohig, Hayes, Plumb, Pruitt, Collins et coll. 2010
Experiential avoidance has been associated with anxiety.
“Experiential avoidance seeks to control the way or frequency of aversive private experiences [37] and has been associated with anxiety [38,39,40,41,42,43,44,45,46,47,48,49,50,51,52,53,54].”
From The Effect of Anxiety and Nutritional Habits on the Body Distortion of Athletes. (2025) · cites this paper as [41]
The ACT Treatment Integrity Coding Manual is a coding system developed to assess treatment integrity in ACT interventions and has been used in previous RCTs of ACT.
“ACT Treatment Integrity Coding Manual [43]: A coding system that has been developed to assess treatment integrity in ACT interventions, which has been used in previous RCTs of ACT [58].”
Researchers have begun to evaluate alternative or augmentative treatments for OCD, such as ACT, that might address adherence and tolerability issues.
“To address this problem, researchers have begun to evaluate alternative or augmentative treatments for OCD, such as Acceptance and Commitment Therapy (ACT), that might address some of these adherence and tolerability issues (Twohig, Hayes, & Masuda, 2006; Twohig et al., 2010).”
From A Comparison of Two Brief Interventions for Obsessional Thoughts: Exposure and Acceptance. (2013) · cites this paper as Twohig et al., 2010
A subsequent randomized control trial compared ACT to progressive relaxation training and found that ACT, without in-session exposure, was an effective and acceptable intervention.
“A subsequent randomized control trial compared ACT to progressive relaxation training and found that ACT, without in-session exposure, was an effective and acceptable intervention (Twohig et al., 2010).”
From A Comparison of Two Brief Interventions for Obsessional Thoughts: Exposure and Acceptance. (2013) · cites this paper as Twohig et al., 2010
The vast majority of investigations into ERP and ACT involve multi-session interventions.
“The vast majority of investigations into ERP and ACT involve multi-session interventions (e.g. Abramowitz, Deacon, & Whiteside, 2010; Twohig et al., 2010).”
From A Comparison of Two Brief Interventions for Obsessional Thoughts: Exposure and Acceptance. (2013) · cites this paper as Twohig et al., 2010
Clinically significant change in OCD severity was observed at greater proportions in the ACT condition relative to PRT.
“Likewise, clinically signi fi cant change in OCD severity was observed at greater proportions in the ACT condition relative to PRT (Twohig, 2007; Twohig, Hayes, et al., 2010).”
From Acceptance and Commitment Therapy in the treatment of anxiety: A systematic review (2013) · cites this paper as Twohig, Hayes, et al., 2010
Two studies of well above average POMRF rating found ACT to be superior to PRT, producing moderate-to-large effect sizes, in the treatment of OCD at follow-up.
“Two studies of well above average POMRF rating found ACT to be superior to PRT, producing moderate-to-large ES, in the treatment of OCD (Twohig, 2007; Twohig, Hayes, et al., 2010).”
From Acceptance and Commitment Therapy in the treatment of anxiety: A systematic review (2013) · cites this paper as Twohig, Hayes, et al., 2010
Medium-to-large changes in self-reported decentering are reported in adults with anxiety and depression following psychological interventions including CBT, acceptance-based approaches, and mindfulness training.
“Medium-to-large changes in self-reported decentering are reported in adults experiencing anxiety and depression following a range of psychological interventions. This includes cognitive behavioural therapy,18 19 acceptance-based approaches20–22 and mindfulness training.23–25”
From Protocol for a randomised controlled trial investigating an intervention to boost decentering in response to distressing mental experiences during adolescence: the decentering in adolescence study (DECADES) (2022) · cites this paper as [22]
The cited portion concerns medium-to-large changes in self-reported decentering after acceptance-based treatment. The Methods’ Measures of Treatment Process section describes measures of psychological flexibility and thought control, and the Process Results report changes in thought control, but neither reports a decentering measure or change in decentering. Searches for decentering and the Experiences Questionnaire found no passage addressing that outcome; page numbers were not available in our copy. (LLM, conf=0.76)
Experimental — accuracy not yet measuredIncreased self-rated decentering is also reported following emotion regulation training and relaxation training.
“Increased self-rated decentering is also reported following emotion regulation training81 and relaxation training80,82.”
From Decentering as a core component in the psychological treatment and prevention of youth anxiety and depression: a narrative review and insight report (2021) · cites this paper as [80]
The Method’s Measures of Treatment Process section identifies the self-report Acceptance and Action Questionnaire as a measure of psychological flexibility, not decentering. The Process Results report improvement on that measure in the progressive relaxation training group, but our copy does not report a self-rated decentering measure or an increase in decentering following relaxation training (searched: decentering, Experiences Questionnaire). (LLM, conf=0.76)
Experimental — accuracy not yet measuredIn adults seeking treatment for anxiety and depression, self-rated decentering increases following CBT, mindfulness-based interventions, and acceptance-based therapies.
“In adults seeking treatment for anxiety and depression, medium-large increases in self-rated decentering are reported following CBT (d = 0.7–0.82) (~43 years)52,73, mindfulness-based interventions (d = 0.6–1.01) (34.49–53.30 years)26,52,74–76 and acceptance-based therapies (d = 0.32–1.85) (37.00–46.40 years)73,77–80.”
From Decentering as a core component in the psychological treatment and prevention of youth anxiety and depression: a narrative review and insight report (2021) · cites this paper as [80]
The citation is attached to the acceptance-based therapies portion of the sentence. In Measures of Treatment Process and Process Results (page unavailable), this ACT trial reports self-rated psychological flexibility, but not self-rated decentering. A search for decentering and a decentering measure found no result establishing the claimed increase. (LLM, conf=0.76)
Experimental — accuracy not yet measuredPlumb and Vilardaga (2010) created a widely used treatment fidelity manual with fewer items, but it was designed specifically for a trial of ACT for people diagnosed with OCD and includes a reasonably lengthy manual.
“Plumb and Vilardaga (2010) created a widely used treatment fidelity manual with fewer items. However, it was designed specifically for a trial of ACT for people diagnosed with OCD (Twohig et al., 2010), and includes a reasonably lengthy manual.”
From The development of the acceptance and commitment therapy fidelity measure (ACT-FM): a delphi study and field test (2019) · cites this paper as Twohig et al., 2010
In a randomized controlled study of ACT, psychological flexibility was found to be the mediator of long-term outcome for patients with OCD.
“in a randomized controlled study of ACT, psychological flexibility was found to be the mediator of long-term outcome for patients with OCD (Twohig et al. 2010).”
From Comparison between obsessive compulsive disorder and panic disorder on metacognitive beliefs, emotional schemas, and cognitive flexibility (2019) · cites this paper as Twohig et al. 2010
Statistics that don’t add up
Each reported p-value recomputed from its test statistic and degrees of freedom.
Inconsistent p-value: χ2 (1) = 10.27, p = .002
MinorThe paper reports p = .002 here; recomputing from the test statistic and its degrees of freedom gives p = .001. The check cannot tell whether the statistic or the p-value is the misprint.
Reported p = .002 · recomputed p = .001
“χ2 (1) = 10.27, p =.002”
Statistics recomputed
Every reported test result, recomputed from its test statistic and degrees of freedom. A result shows as not adding up only once an independent check has confirmed it.
- Doesn’t add upχ²(1) = 10.27reported p = .002 · recomputed p = .001
“χ2 (1) = 10.27, p = .002”
- ConsistentF(1, 80.64) = 115.54reported p < .001 · recomputed p < .001
“F (1, 80.64) = 115.54, p < .001”
- ConsistentF(1, 92.98) = 1.16reported p = .28 · recomputed p = .284
“F (1, 92.98) = 1.16, p = .28”
- ConsistentF(1, 80.64) = 5.15reported p = .026 · recomputed p = .026
“F (1, 80.64) = 5.15, p = .026”
- Consistentt(80.9) = -9.4reported p < .001 · recomputed p < .001
“t (80.90) = -9.40, p < .001”
- Consistentt(80.4) = -5.88reported p < .001 · recomputed p < .001
“t (80.40) = -5.88, p < .001”
- Consistentt(80.64) = 2.27reported p = .026 · recomputed p = .026
“t (80.64) = 2.27, p = .026”
- Consistentχ²(1) = 6.96reported p < .009 · recomputed p = .008
“χ2 (1) = 6.96, p < .009”
- Consistentχ²(1) = 10.3reported p < .002 · recomputed p = .001
“χ2 (1) = 10.30, p < .002”
- Consistentχ²(1) = 18.24reported p < .001 · recomputed p < .001
“χ2 (1) = 18.24, p < .001”
- ConsistentF(1, 55.32) = 0.35reported p = .56 · recomputed p = .557
“F (1, 55.32) = .35, p = .56”
- ConsistentF(2, 69.63) = 44.14reported p < .001 · recomputed p < .001
“F (2, 69.63) = 44.14, p < .001”
- ConsistentF(2, 69.63) = 5.61reported p = .006 · recomputed p = .005
“F (2, 69.63) = 5.61, p = .006”
- Consistentt(59.65) = -3.23reported p = .002 · recomputed p = .002
“t (59.65) = -3.23, p = .002”
- Consistentt(62.82) = -2.06reported p = .044 · recomputed p = .044
“t (62.82) = -2.06, p = .044”
- ConsistentF(1, 66.53) = 2.41reported p = .126 · recomputed p = .125
“F (1, 66.53) = 2.41, p = .126”
- ConsistentF(2, 64.62) = 11.44reported p < .001 · recomputed p < .001
“F (2, 64.62) = 11.44, p < .001”
- ConsistentF(2, 64.62) = 2.99reported p = .057 · recomputed p = .057
“F (2, 64.62) = 2.99, p = .057”
- Consistentt(63.49) = 0.06reported p = .96 · recomputed p = .952
“t (63.49) = .06, p = .96”
- Consistentt(70.22) = 1.96reported p = .054 · recomputed p = .054
“t (70.22) = 1.96, p = .054”
- ConsistentF(1, 69.78) = 7.3reported p = .009 · recomputed p = .009
“F (1, 69.78) = 7.30, p = .009”
- ConsistentF(2, 66.36) = 22.14reported p < .001 · recomputed p < .001
“F (2, 66.36) = 22.14, p < .001”
- ConsistentF(2, 66.35) = 5.6reported p = .006 · recomputed p = .006
“F (2, 66.35) = 5.60, p = .006”
- Consistentt(70.22) = -2.5reported p = .015 · recomputed p = .015
“t (70.22) = -2.50, p = .015”
- Consistentt(67.89) = -0.92reported p = .36 · recomputed p = .361
“t (67.89) = -.92, p = .36”
- ConsistentF(1, 77.28) = 3.18reported p = .079 · recomputed p = .078
“F (1, 77.28) = 3.18, p = .079”
- ConsistentF(2, 70.43) = 17.88reported p < .001 · recomputed p < .001
“F (2, 70.43) = 17.88, p < .001”
- ConsistentF(2, 70.43) = 5.11reported p = .008 · recomputed p = .008
“F (2, 70.43) = 5.11, p = .008”
- Consistentt(72.51) = -3.14reported p = .002 · recomputed p = .002
“t (72.51) = -3.14, p = .002”
- Consistentt(75.7) = 1.77reported p = .082 · recomputed p = .081
“t (75.70) = 1.77, p = .082”
- ConsistentF(1, 76.34) = 1.25reported p = .27 · recomputed p = .267
“F (1, 76.34) = 1.25, p = .27”
- ConsistentF(1, 71.72) = 16.32reported p < .001 · recomputed p < .001
“F (1, 71.72) = 16.32, p < .001”
- ConsistentF(1, 71.72) = 11.39reported p = .001 · recomputed p = .001
“F (1, 71.72) = 11.39, p = .001”
- Consistentt(71.93) = -5.32reported p < .001 · recomputed p < .001
“t (71.93) = -5.32, p < .001”
- Consistentt(71.52) = -0.46reported p = .65 · recomputed p = .647
“t (71.52) = -.46, p = .65”
- ConsistentF(1, 117.43) = 1.41reported p = .24 · recomputed p = .237
“F (1, 117.43) = 1.41, p = .24”
- ConsistentF(1, 135.78) = 18.94reported p < .001 · recomputed p < .001
“F (1, 135.78) = 18.94, p < .001”
- ConsistentF(1, 135.78) = 3.33reported p = .07 · recomputed p = .070
“F (1, 135.78) = 3.33, p = .07”
- Consistentt(135.54) = -4.46reported p < .001 · recomputed p < .001
“t (135.54) = -4.46, p < .001”
- Consistentt(136) = -1.75reported p = .082 · recomputed p = .082
“t (136.00) = -1.75, p = .082”
- Consistentt(65) = 3.57reported p = .001 · recomputed p < .001
“t (65) = 3.57, p = .001”
- ConsistentF(1, 64) = 5.25reported p = .025 · recomputed p = .025
“F (1,64) = 5.25, p = .025”
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
Each contradiction between two passages listed here was confirmed by an independent check.
Sample size by sex does not match reported participant total
MajorThe abstract says 79 adults participated and 66% were female, but the participant section gives 61% women in the study. These percentages cannot both describe the same sample unless the denominator or one of the percentages is different.
“79 adults (66% Female) diagnosed with OCD (M age=37, 89% Caucasian) participated in a randomized clinical trial”
“There were slightly more women in the study (61%); average age of participants was 37 years (SD=15.5, range 18-67).”
Comorbidity percentage conflicts with diagnosis counts
MinorThe listed counts total 36 participants with at least one additional diagnosis, or about 46% of the 79 participants, rather than the stated 51%.
“all participants met criteria for OCD as their primary diagnosis with 51% receiving one or greater additional diagnoses.”
“The frequencies of total number of co-occurring diagnoses per individual per condition were as follows: one 14ACT/7PRT, two 4ACT/8PRT, and three 1ACT/2PRT.”
Two different percentages are given for female participants
MinorThe abstract reports 66% female participants, while the participant description reports 61% for the same study sample.
“79 adults (66% Female) diagnosed with OCD”
“There were slightly more women in the study (61%); average age of participants was 37 years”
Thought-control test statistic has the wrong sign
MinorThe reported negative estimated difference divided by its positive standard error gives a negative t statistic, not the positive statistic printed for the follow-up comparison.
Reported 1.77 · recomputed -1.760618
“Estimated Mdiff = -4.56, SE = 2.59, t (75.70) = 1.77, p = .082”
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“An number of 38 per condition was required for power of .8 to detect the average between group effect size (d 0.66) in the existing ACT literature across all diagnoses (Hayes et al., 2006).”
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MethodContext, ambiguity, and unlearning: sources of relapse after behavioral extinction
Bouton, M. E. (2002) · Biological Psychiatry · doi:10.1016/s0006-3223(02)01546-9 · Cited by 1,662 · cited 1× · see citing works
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“ERP suffers from a dropout rate of approximately 25% (Abramowitz, Taylor, & McKay, 2009), and overt refusal rates, though often not reported in the literature, represent an additional 5%–22% of participants (e.g., Foa et al., 2005; McLean et al., 2001).”
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“The average therapist contact time for ERP and ERP–CT outcome studies (weighted by the size of the study) was 27.4 hr (range: 9–48) for the studies in the review conducted by Abramowitz, Taylor, and McKay (2009).”
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“Effect sizes for MMRM outcomes were calculated as specified by Wackerly, Mendenhall, and Scheaffer (2008) and for HLM by examining end-point outcomes as suggested by Feingold (2009).”
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“The Thought Control Questionnaire (Wells & Davies, 1994) is a 30-item self-report measure that assesses the use of thought control strategies.”
MethodThe valued living questionnaire: defining and measuring valued action within a behavioral framework
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Thought Action Fusion in Obsessive Compulsive Disorder
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Relaxation training for anxiety: a ten-years systematic review with meta-analysis
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“Component studies of these processes in isolation (outside the entire treatment package) support their utility in a variety of contexts (e.g., Levitt et al., 2004; Masuda, Hayes, Sackett, & Twohig, 2004).”
BackgroundDevelopment of a modified treatment evaluation inventory
Kelley, M. L., Heffer, R. W., Gresham, F. M., & Elliott, S. N. (1989) · Journal of Psychopathology and Behavioral Assessment · doi:10.1007/bf00960495 · Cited by 409 · see citing works
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“The present study is below the range of durations found in that review (or an earlier review by Fisher & Wells, 2005) and represents 29%–31% of the average duration of comparable protocols.”
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“Merely the act of exposing oneself to a feared situation and staying in that situation for a meaningful period is generally therapeutic (Abramowitz, 1996), but there is no consensus about the psychological processes that account for this benefit (Steketee & Barlow, 2002).”
BackgroundCognitive versus behavior therapy in the group treatment of obsessive–compulsive disorder
McLean, P. D., Whittal, M. L., Thordarson, D. S., Taylor, S., Söchting, I., Koch, W. J., Paterson, R., & Anderson, K. W. (2001) · Journal of Consulting and Clinical Psychology · doi:10.1037/0022-006x.69.2.205 · Cited by 332 · cited 1× · see citing works
“ERP suffers from a dropout rate of approximately 25% (Abramowitz, Taylor, & McKay, 2009), and overt refusal rates, though often not reported in the literature, represent an additional 5%–22% of participants (e.g., Foa et al., 2005; McLean et al., 2001).”
BackgroundMasuda, A., Hayes, S. C., Sackett, C. F., & Twohig, M. P. (2004) · Behaviour Research and Therapy · doi:10.1016/j.brat.2003.10.008 · Cited by 317 · see citing works
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“Arch and Craske (2008), for example, postulated that exposure involves “optimizing learning . . . based on increasing tolerance for fear and anxiety” (p. 269).”
BackgroundReliability of the structured clinical interview for DSM-iII-R: an evaluative review
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“The protocol used in the ACT for OCD investigation is the same as that used by Twohig et al. (2006a). Although book-length presentations of ACT for anxiety are available (e.”
MethodTwohig, M. P., Hayes, S. C., & Masuda, A. (2006) · Behavior Therapy · doi:10.1016/j.beth.2005.02.001 · Cited by 290 · cited 2× · see citing works
“A coding system that was successfully employed in a previous study on ACT for OCD (Twohig et al., 2006a) was used in the current study to rate treatment integrity.”
MethodSelf-citationFALS-STEWART, W., MARKS, A. P., & SCHAFER, J. (1993) · The Journal of Nervous and Mental Disease · doi:10.1097/00005053-199303000-00007 · Cited by 279 · cited 1× · see citing works
“Effect sizes for MMRM outcomes were calculated as specified by Wackerly, Mendenhall, and Scheaffer (2008) and for HLM by examining end-point outcomes as suggested by Feingold (2009). Effect sizes were calculated with Cohen’s (1988) cutoffs (small 0.”
MethodThe Cruelest Cure? Ethical Issues in the Implementation of Exposure-Based Treatments
Olatunji, B. O., Deacon, B. J., & Abramowitz, J. S. (2009) · Cognitive and Behavioral Practice · doi:10.1016/j.cbpra.2008.07.003 · Cited by 273 · see citing works
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Handbook of assessment and treatment planning for psychological disorders.
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Self-citationREYNOLDS, M., & WELLS, A. (1999) · Psychological Medicine · doi:10.1017/s003329179900104x · Cited by 179 · cited 1× · see citing works
“This is a widely used measure of this construct for obsessive-compulsive and anxiety-related disorders and has been shown to change as a result of cognitive behavioral interventions (e.g., Reynolds & Wells, 1999).”
BackgroundLeonard, H. L., Ale, C. M., Freeman, J. B., Garcia, A. M., & Ng, J. (2005) · Child and Adolescent Psychiatric Clinics of North America · doi:10.1016/j.chc.2005.06.002 · Cited by 173 · see citing works
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“A lack of psychological flexibility is associated with OCD symptom levels in adults and children (Abramowitz, Lackey, & Wheaton, 2009; Briggs & Price, 2009).”
BackgroundTwohig, M. P., Hayes, S. C., & Masuda, A. (2006) · Behaviour Research and Therapy · doi:10.1016/j.brat.2005.10.002 · Cited by 143 · cited 2× · see citing works
“A coding system that was successfully employed in a previous study on ACT for OCD (Twohig et al., 2006a) was used in the current study to rate treatment integrity.”
MethodSelf-citationTwohig, M. P., & Woods, D. W. (2004) · Behavior Therapy · doi:10.1016/s0005-7894(04)80021-2 · Cited by 141 · cited 1× · see citing works
“There is evidence for the effectiveness of ACT in the treatment of OCD spectrum disorders such as skin picking and trichotillomania (Twohig, Hayes, & Masuda, 2006b; Twohig & Woods, 2004; Woods, Wetterneck, & Flessner, 2006).”
BackgroundSelf-citationPsychotherapists in Clinical Practice: Cognitive and Behavioral Perspectives
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Obsessive–compulsive symptoms: The contribution of obsessional beliefs and experiential avoidance
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The thought-action fusion scale: further evidence for its reliability and validity
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Exposure therapy has a public relations problem
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“ERP is also grossly underutilized (Olatunji, Deacon, & Abramowitz, 2009), perhaps in part because clinicians find it aversive (Richard & Gloster, 2007) and the public rates it negatively when the methods are described (Richard & Gloster, 2007).”
BackgroundMethodStructured and semistructured diagnostic interviews.
Summerfeldt, L. J., Ovanessian, M. M., & Antony, M. M. (2002) · Cited by 46 · see citing works
Trichotillomania: Therapist Guide
Woods, D. W., & Twohig, M. P. (2008) · Oxford University Press eBooks · doi:10.1093/med:psych/9780195336030.001.0001 · Cited by 12 · cited 2× · see citing works
“…ACT for OCD investigation is the same as that used by Twohig et al. (2006a).1 Although book-length presentations of ACT for anxiety are available (e.g., Eifert & Forsyth, 2005; Woods & Twohig, 2008), ACT is still unfamiliar enough that an extended characterization of the protocol seems warranted.”
MethodSelf-citation
Flagged first, then by citations
2 of the 49 references couldn’t be matched to a known paper.
Cited by
Sorted by citations
Hayes, S. C., Levin, M. E., Plumb-Vilardaga, J., Villatte, J. L., & Pistorello, J. (2013) · Behavior Therapy · doi:10.1016/j.beth.2009.08.002 · Cited by 1,120 · see citing works
Self-citationKatzman, M. A., Bleau, P., Blier, P., Chokka, P., Kjernisted, K., Van Ameringen, M., & the Canadian Anxiety Guidelines Initiative Group on behalf of the Anxiety Disorders Association of Canada/Association Canadienne des troubles anxieux and McGill University (2014) · BMC Psychiatry · doi:10.1186/1471-244x-14-s1-s1 · Cited by 1,090 · see citing works
Acceptance and Commitment Therapy as a Unified Model of Behavior Change
Hayes, S. C., Pistorello, J., & Levin, M. E. (2012) · The Counseling Psychologist · doi:10.1177/0011000012460836 · Cited by 718 · see citing works
“, Wicksell, Ahlqvist, Bring, Melin, & Olsson, 2008), coping with psychosis (Bach & Hayes, 2002), obsessive compulsive disorder (Twohig et al., 2010) and mixed anxiety disorders (Arch et al.”
InfluentialSelf-citationOlatunji, B. O., Davis, M. L., Powers, M. B., & Smits, J. A. J. (2013) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2012.08.020 · Cited by 659 · see citing works
Hofmann, S. G., Sawyer, A. T., Fang, A., & Asnaani, A. (2012) · Depression and Anxiety · doi:10.1002/da.21888 · Cited by 630 · see citing works
“[75–79] This process can be effectively targeted by promoting adaptive emotion regulation strategies in the context of modern psychological treatments, including Acceptance-Based Behavioral Treatment for GAD,[80] Emotion Regulation Therapy for GAD,[81] and various ACT protocols for anxiety disorders.[82] These and oth…”
BackgroundThe efficacy of Acceptance and Commitment Therapy: An updated systematic review and meta-analysis
Öst, L.-G. (2014) · Behaviour Research and Therapy · doi:10.1016/j.brat.2014.07.018 · Cited by 476 · see citing works
“Twohig et al. (2010) found ACT to be significantly better than progressive relaxation training, which, however, never has been an established treatment for OCD.”
BackgroundArch, J. J., Eifert, G. H., Davies, C., Vilardaga, J. C. P., Rose, R. D., & Craske, M. G. (2012) · Journal of Consulting and Clinical Psychology · doi:10.1037/a0028310 · Cited by 443 · see citing works
“…clinical trial provide nascent evidence that ACT is an effective treatment for anxiety disorders, including obsessive-compulsive disorder (Twohig et al., 2010), social anxiety disorder (Dalrymple & Herbert, 2007), panic disorder (Eifert et al., 2009), generalized anxiety disorder…”
Acceptance and commitment therapy for anxiety and OCD spectrum disorders: An empirical review
Bluett, E. J., Homan, K. J., Morrison, K. L., Levin, M. E., & Twohig, M. P. (2014) · Journal of Anxiety Disorders · doi:10.1016/j.janxdis.2014.06.008 · Cited by 306 · see citing works
“In the RCT by Zettle (2003) comparing ACT to systematic desensitization for math anxiety, results indicated that pre-treatment levels of psychological inflexibility were related to decreases in anxiety at post-treatment only in the ACT condition.”
Self-citationAcceptance and Commitment Therapy as a Treatment for Anxiety and Depression
Twohig, M. P., & Levin, M. E. (2017) · Psychiatric Clinics of North America · doi:10.1016/j.psc.2017.08.009 · Cited by 268 · see citing works
“Yadegari et al. (2014) N=16, 18-20 YO; ACT vs WL ACT > WL; SPAI: ACT 134 pre, 57 post; WL 148 pre 149 post Craske et al. (2014) N=87; ACT vs CBT vs WL, Assessments at pre, post, 6 mo, and 12 mo ACT = CBT, both > WL; response rates post 52% CBT, 41% ACT, 6 mo FU 57% CBT 53% ACT, 12 mo FU 40% CBT, 41% ACT Obsessive-Comp…”
BackgroundInfluentialSelf-citationThe third wave of cognitive behavioural therapies
Kahl, K. G., Winter, L., & Schweiger, U. (2012) · Current Opinion in Psychiatry · doi:10.1097/yco.0b013e328358e531 · Cited by 265 · see citing works
“ACT was superior to progressive relaxation training in reducing symptoms of obsessive compulsive disorder in 79 patients [11].”
MethodPsychological flexibility: What we know, what we do not know, and what we think we know
Doorley, J. D., Goodman, F. R., Kelso, K. C., & Kashdan, T. B. (2020) · Social and Personality Psychology Compass · doi:10.1111/spc3.12566 · Cited by 264 · see citing works
(2012) · Re-Unir (International University of La Rioja) · Cited by 262 · see citing works
Treatment of Obsessive Compulsive Disorder
Franklin, M. E., & Foa, E. B. (2011) · Annual Review of Clinical Psychology · doi:10.1146/annurev-clinpsy-032210-104533 · Cited by 227 · see citing works
Acceptance and Commitment Therapy in the treatment of anxiety: A systematic review
Swain, J., Hancock, K., Hainsworth, C., & Bowman, J. (2013) · Clinical Psychology Review · doi:10.1016/j.cpr.2013.07.002 · Cited by 207 · see citing works
Assessing Psychological Flexibility: What Does It Add Above and Beyond Existing Constructs?
Gloster, A. T., Klotsche, J., Chaker, S., Hummel, K. V., & Hoyer, J. (2011) · Psychological Assessment · doi:10.1037/a0024135 · Cited by 206 · see citing works
TRANSDIAGNOSTIC TREATMENT FOR ANXIETY AND DEPRESSION: The Cutting Edge: Transdiagnostic Therapy
Craske, M. G. (2012) · Depression and Anxiety · doi:10.1002/da.21992 · Cited by 208 · see citing works
“[22] Whereas moderate levels of anxiety sensitivity and absence of comorbid mood disorder predicted better anxiety outcomes from CBT than ACT, comorbid mood disorders predicted better anxiety outcomes from ACT than CBT.[23] Similarly, we found generally comparable effects between MBSR (combined with psychoeducation an…”
ResultAcceptance and Commitment Therapy as a Treatment for Problematic Internet Pornography Viewing
Twohig, M. P., & Crosby, J. M. (2010) · Behavior Therapy · doi:10.1016/j.beth.2009.06.002 · Cited by 198 · see citing works
Self-citationArch, J. J., Wolitzky-Taylor, K. B., Eifert, G. H., & Craske, M. G. (2012) · Behaviour Research and Therapy · doi:10.1016/j.brat.2012.04.007 · Cited by 194 · see citing works
“Case studies, multiple-baseline studies, and an initial randomized study (Twohig et al., 2010) provide nascent evidence that ACT is an effective treatment for anxiety disorders, including obsessive compulsive disorder (Twohig, Hayes, & Masuda, 2006; Twohig et al.”
InfluentialJacoby, R. J., & Abramowitz, J. S. (2016) · Clinical Psychology Review · doi:10.1016/j.cpr.2016.07.001 · Cited by 188 · see citing works
The Role of Sexual Compulsivity, Impulsivity, and Experiential Avoidance in Internet Pornography Use
Wetterneck, C. T., Burgess, A. J., Short, M. B., Smith, A. H., & Cervantes, M. E. (2012) · The Psychological Record · doi:10.1007/bf03395783 · Cited by 172 · see citing works
“…is consistent with previous research indicating that experiential avoidance may maintain and/or exacerbate compulsive (Hayes et al., 1996; Twohig et al., 2010), impulsive (Begotka et al., 2004; Flessner et al., 2008), and addictive behaviors (Hayes et al., 2004; Stotts et al., 2009;…”
BackgroundResultThompson, E. M., Destree, L., Albertella, L., & Fontenelle, L. F. (2021) · Behavior Therapy · doi:10.1016/j.beth.2020.07.002 · Cited by 168 · see citing works
Getting better with age: the relationship between age, acceptance, and negative affect
Shallcross, A. J., Ford, B. Q., Floerke, V. A., & Mauss, I. B. (2013) · Journal of Personality and Social Psychology · doi:10.1037/a0031180 · Cited by 153 · see citing works
“Second, accepting negative experiences appears to causally contribute to lower negative affect (Campbell-Sills et al., 2006b; Twohig et al., 2010).”
BackgroundInfluentialTwohig, M. P., Abramowitz, J. S., Smith, B. M., Fabricant, L. E., Jacoby, R. J., Morrison, K. L., Bluett, E. J., Reuman, L., Blakey, S. M., & Ledermann, T. (2018) · Behaviour Research and Therapy · doi:10.1016/j.brat.2018.06.005 · Cited by 156 · see citing works
Self-citationReinholt, N., & Krogh, J. (2014) · Cognitive Behaviour Therapy · doi:10.1080/16506073.2014.897367 · Cited by 146 · see citing works
Quality of Life in Obsessive-Compulsive Disorder: Impact of the Disorder and of Treatment
Subramaniam, M., Soh, P., Vaingankar, J., Picco, L., & Chong, S. (2013) · CNS Drugs · doi:10.1007/s40263-013-0056-z · Cited by 155 · see citing works
“[80] found that patients with OCD showed improvements on the Quality of Life Scale [81] following both acceptance and commitment therapy (ACT) and progressive relaxation techniques (PRT).”
Hacker, T., Stone, P., & MacBeth, A. (2016) · Journal of Affective Disorders · doi:10.1016/j.jad.2015.10.053 · Cited by 130 · see citing works
Feingold, A. (2014) · Journal of Consulting and Clinical Psychology · doi:10.1037/a0037721 · Cited by 126 · see citing works
Constantino, M. J., Coyne, A. E., Boswell, J. F., Iles, B. R., & Vîslă, A. (2018) · Psychotherapy · doi:10.1037/pst0000168 · Cited by 125 · see citing works
Forman, E. M., Shaw, J. A., Goetter, E. M., Herbert, J. D., Park, J. A., & Yuen, E. K. (2012) · Behavior Therapy · doi:10.1016/j.beth.2012.04.004 · Cited by 113 · see citing works
Burckhardt, R., Manicavasagar, V., Batterham, P. J., & Hadzi-Pavlovic, D. (2016) · Journal of School Psychology · doi:10.1016/j.jsp.2016.05.008 · Cited by 112 · see citing works
“, 2012; Avdagic, Morrissey, & Boschen, 2014), obsessive-compulsive disorder (Twohig et al., 2010), drug and nicotine dependence (Hernández-López, Luciano, Bricker, Roales-Nieto, & Montesinos, 2009; Luoma, Kohlenberg, Hayes, & Fletcher, 2012), borderline personality disorder (Gratz & Gunderson, 2006; Morton, Snowdon, G…”
Herzberg, K. N., Sheppard, S. C., Forsyth, J. P., Credé, M., Earleywine, M., & Eifert, G. H. (2012) · Psychological Assessment · doi:10.1037/a0027782 · Cited by 113 · see citing works
Distress tolerance and obsessions: an integrative analysis
Cougle, J. R., Timpano, K. R., Fitch, K. E., & Hawkins, K. A. (2011) · Depression and Anxiety · doi:10.1002/da.20846 · Cited by 105 · see citing works
“Researchers have found fear of negative emotion to be strongly related to OCD symptoms,[16] and anxiety sensitivity, a related construct, is elevated among individuals with OCD.”
InfluentialA Perspective on the Similarities and Differences Between Mindfulness and Relaxation
Luberto, C. M., Hall, D. L., Park, E. R., Haramati, A., & Cotton, S. (2020) · Global Advances in Health and Medicine · doi:10.1177/2164956120905597 · Cited by 104 · see citing works
Nordin, L., & Rorsman, I. (2012) · Journal of Rehabilitation Medicine · doi:10.2340/16501977-0898 · Cited by 106 · see citing works
Mindfulness-based cognitive therapy as an augmentation treatment for obsessive-compulsive disorder.
Key, B. L., Rowa, K., Bieling, P., McCabe, R., & Pawluk, E. J. (2017) · Clinical Psychology & Psychotherapy · doi:10.1002/cpp.2076 · Cited by 103 · see citing works
“In addition, a number of studies have examined the effectiveness of acceptance and commitment therapy (ACT) and acceptance‐based behaviour therapy (ABBT), which incorporate mindfulness exercises, in the treatment of OCD and found promising results (e.g., Twohig, Hayes, & Masuda, 2006; Twohig et al., 2010).”
BackgroundResultEmotion regulation difficulties in obsessive-compulsive disorder
Yap, K., Mogan, C., Moriarty, A., Dowling, N., Blair‐West, S., Gelgec, C., & Moulding, R. (2018) · Journal of Clinical Psychology · doi:10.1002/jclp.22553 · Cited by 102 · see citing works
Hertenstein, E., Rose, N. L. J., Voderholzer, U., Heidenreich, T., Nissen, C., Thiel, N., Herbst, N., & Külz, A. K. (2012) · BMC Psychiatry · doi:10.1186/1471-244x-12-185 · Cited by 102 · see citing works
O'Neill, L., Latchford, G., McCracken, L. M., & Graham, C. D. (2019) · Journal of Contextual Behavioral Science · doi:10.1016/j.jcbs.2019.08.008 · Cited by 87 · see citing works
“Several ACT adherence and competency scales exist (e.g. Luoma, Hayes, & Walser, 2007; 2017; McGrath & Forman, 2012; Plumb & Vilardaga, 2010; Pollard, 2010; Twohig et al., 2010).”
BackgroundNew Directions in the Cognitive-Behavioral Treatment of OCD: Theory, Research, and Practice
Abramowitz, J. S., Blakey, S. M., Reuman, L., & Buchholz, J. L. (2018) · Behavior Therapy · doi:10.1016/j.beth.2017.09.002 · Cited by 98 · see citing works
Internet-based cognitive behavior therapy for obsessive compulsive disorder: A pilot study
Andersson, E., Ljótsson, B., Hedman, E., Kaldo, V., Paxling, B., Andersson, G., Lindefors, N., & Rück, C. (2011) · BMC Psychiatry · doi:10.1186/1471-244x-11-125 · Cited by 94 · see citing works
“Second, the OCD symptom ratings were lower in this sample than in other trials where Y-BOCS baseline mean ratings range from 24 to 29 [62-64].”
ResultThe effect of trauma on the severity of obsessive-compulsive spectrum symptoms: a meta-analysis
Miller, M. L., & Brock, R. L. (2017) · Journal of Anxiety Disorders · doi:10.1016/j.janxdis.2017.02.005 · Cited by 93 · see citing works
Stress and coping in women with breast cancer:unravelling the mechanisms to improve resilience
Borgi, M., Collacchi, B., Ortona, E., & Cirulli, F. (2020) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2020.10.011 · Cited by 90 · see citing works
The Application of Acceptance and Commitment Therapy to Obsessive-Compulsive Disorder
Twohig, M. P. (2009) · Cognitive and Behavioral Practice · doi:10.1016/j.cbpra.2008.02.008 · Cited by 89 · see citing works
Self-citationPahnke, J., Lundgren, T., Hursti, T., & Hirvikoski, T. (2014) · Autism · doi:10.1177/1362361313501091 · Cited by 88 · see citing works
“ACT has proven to be effective in a diverse range of clinical conditions such as anxiety disorders, stress and substance abuse (Bohlmeijer et al., 2011; Twohig et al., 2010).”
BackgroundBennett, M. P., Knight, R., Patel, S., So, T., Dunning, D., Barnhofer, T., Smith, P., Kuyken, W., Ford, T., & Dalgleish, T. (2021) · Translational Psychiatry · doi:10.1038/s41398-021-01397-5 · Cited by 81 · see citing works
Kyrios, M., Ahern, C., Fassnacht, D. B., Nedeljkovic, M., Moulding, R., & Meyer, D. (2018) · Journal of Medical Internet Research · doi:10.2196/jmir.9566 · Cited by 86 · see citing works
“As justification, the most recent evaluation using manualized PRT has shown it to be effective and credible in treating OCD [17], although its efficacy has not been a consistent finding in the past [41,42].”
BackgroundMethodResultKroska, E. B., Miller, M. L., Roche, A. I., Kroska, S. K., & O’Hara, M. W. (2018) · Journal of Affective Disorders · doi:10.1016/j.jad.2017.08.039 · Cited by 80 · see citing works
An update on the efficacy of psychological treatments for obsessive-compulsive disorder in adults
Ponniah, K., Magiati, I., & Hollon, S. D. (2013) · Journal of Obsessive-Compulsive and Related Disorders · doi:10.1016/j.jocrd.2013.02.005 · Cited by 79 · see citing works
“N IH -PA Author M anuscript N IH -PA Author M anuscript N IH -PA Author M anuscript Author, year, country Diagnostic method, OCD subtype/s (if given) Treatment/control conditions, main outcomes (USA; CAN) Kenwright et al., 2005 (GBR) DSM-IV; Structured interview; Mixed subtypes Computer-guided ERP with requested phone…”
BackgroundMethodInfluentialAssessing treatment integrity in acceptance and commitment therapy: strategies and suggestions
Plumb, J. C., & Vilardaga, R. (2010) · International Journal of Behavioral Consultation and Therapy · doi:10.1037/h0100912 · Cited by 75 · see citing works
Self-citationA meta-analysis of dropout rates in acceptance and commitment therapy
Ong, C. W., Lee, E. B., & Twohig, M. P. (2018) · Behaviour Research and Therapy · doi:10.1016/j.brat.2018.02.004 · Cited by 69 · see citing works
Self-citationTwohig, M. P., Vilardaga, J. C. P., Levin, M. E., & Hayes, S. C. (2015) · Journal of Contextual Behavioral Science · doi:10.1016/j.jcbs.2015.07.001 · Cited by 72 · see citing works
“See Twohig et al. (2010) for details.”
InfluentialSelf-citationAcceptance and Commitment Therapy for the Treatment of Posttraumatic Stress Among Adolescents
Woidneck, M. R., Morrison, K. L., & Twohig, M. P. (2014) · Behavior Modification · doi:10.1177/0145445513510527 · Cited by 73 · see citing works
“Treatment adherence was assessed using a standardized treatment integrity scoring system that has been used in previous ACT research (Armstrong et al., 2013; Twohig et al., 2010).”
InfluentialSelf-citationArmstrong, A. B., Morrison, K. L., & Twohig, M. P. (2013) · Journal of Cognitive Psychotherapy · doi:10.1891/0889-8391.27.2.175 · Cited by 68 · see citing works
“disorder (Roemer, Orsillo, & Salters-Pedneault, 2008), epilepsy (Lundgren, Dahl, Yardi, & Melin, 2008), and OCD (Twohig et al., 2010).”
InfluentialSelf-citationEustis, E. H., Hayes-Skelton, S. A., Roemer, L., & Orsillo, S. M. (2016) · Behaviour Research and Therapy · doi:10.1016/j.brat.2016.09.012 · Cited by 70 · see citing works
“On the other hand, there is some evidence that traditional CBT is as effective as ABBT in reducing EA (Arch et al., 2012b; Twohig et al., 2010), which suggests that EA could be considered as a common mechanism.”
BackgroundLa thérapie d’acceptation et d’engagement
Ducasse, D., & Fond, G. (2015) · L Encéphale · doi:10.1016/j.encep.2013.04.017 · Cited by 71 · see citing works
Franklin, M. E., Kratz, H. E., Freeman, J. B., Ivarsson, T., Heyman, I., Sookman, D., McKay, D., Storch, E. A., & March, J. S. (2015) · Psychiatry Research · doi:10.1016/j.psychres.2015.02.009 · Cited by 69 · see citing works
I Am > Trauma: Experimentally Reducing Event Centrality and PTSD Symptoms in a Clinical Trial
Boals, A., & Murrell, A. R. (2016) · Journal of Loss and Trauma · doi:10.1080/15325024.2015.1117930 · Cited by 69 · see citing works
“To monitor treatment adherence in the experimental group, slight modifications were made to a previously published, manualized therapist adherence scale (i.e., the ACT for OCD Adherence Scale created by Twohig et al., 2010).”
MethodA review of metacognition in psychological models of obsessive–compulsive disorder
Rees, C. S., & Anderson, R. (2013) · Clinical Psychologist · doi:10.1111/cp.12001 · Cited by 66 · see citing works
“This same ACT protocol was later compared with a progressive relaxation training (PRT) control condition in the first randomised controlled trial of ACT for OCD (Twohig et al., 2010).”
MethodJuncos, D. G., & Markman, E. J. (2016) · Psychology of Music · doi:10.1177/0305735615596236 · Cited by 63 · see citing works
“…actually preceded changes in specific outcome variables within nonclinical samples (Gifford et al., 2004; Hesser, Westin, Hayes, & Andersson, 2009; Zettle & Hayes, 1986) and clinical samples (Dalrymple & Herbert, 2007; Kocovski, Fleming, Hawley, Huta, & Antony, 2013; Twohig et al., 2010).”
BackgroundInfluentialA randomized controlled trial of acceptance and commitment therapy for clinical perfectionism
Ong, C. W., Lee, E. B., Krafft, J., Terry, C. L., Barrett, T. S., Levin, M. E., & Twohig, M. P. (2019) · Journal of Obsessive-Compulsive and Related Disorders · doi:10.1016/j.jocrd.2019.100444 · Cited by 60 · see citing works
Self-citationThe empirically supported status of acceptance and commitment therapy: An update.
Smout, M. F., Hayes, L., Atkins, P. W. B., Klausen, J., & Duguid, J. E. (2012) · Clinical Psychologist · doi:10.1111/j.1742-9552.2012.00051.x · Cited by 61 · see citing works
“Twohig et al. (2010) randomised 79 adults with chronic (M = 20.5 years) OCD to ACT or progressive muscle relaxation (PMR).”
InfluentialExploring cultural competence in acceptance and commitment therapy outcomes.
Woidneck, M. R., Pratt, K. M., Gundy, J. M., Nelson, C. R., & Twohig, M. P. (2012) · Professional Psychology Research and Practice · doi:10.1037/a0026235 · Cited by 60 · see citing works
Self-citationA Contemporary View of Applied Relaxation for Generalized Anxiety Disorder
Hayes-Skelton, S., Roemer, L., Orsillo, S., & Borkovec, T. (2013) · Cognitive Behaviour Therapy · doi:10.1080/16506073.2013.777106 · Cited by 54 · see citing works
“…intended, often only focusing on the relaxation components, omitting the appli cation practice (see Beck, Stanley, Baldwin, Deagle, & Averill, 1994; Twohig et al., 2010) or describing the treatment in a way that makes it difficult to ascertain the amount of focus on the application training (e.g.,…”
BackgroundSarris, J., Camfield, D., & Berk, M. (2012) · Journal of Affective Disorders · doi:10.1016/j.jad.2011.04.051 · Cited by 59 · see citing works
Shabani, M. J., Mohsenabadi, H., Omidi, A., Lee, E. B., Twohig, M. P., Ahmadvand, A., & Zanjani, Z. (2019) · Journal of Obsessive-Compulsive and Related Disorders · doi:10.1016/j.jocrd.2019.04.003 · Cited by 56 · see citing works
“that purposefully excluded in-session exposure exercises (Twohig et al., 2010).”
Self-citationAcceptance and Commitment Therapy as a Treatment for Scrupulosity in Obsessive Compulsive Disorder
Dehlin, J. P., Morrison, K. L., & Twohig, M. P. (2013) · Behavior Modification · doi:10.1177/0145445512475134 · Cited by 56 · see citing works
“The treatment was based on ACT for OCD (Twohig et al., 2006; Twohig et al., 2010), and was tailored for scrupulosity-based OCD specifically.”
InfluentialSelf-citationBrief acceptance and commitment therapy and exposure for panic disorder: A pilot study
Meuret, A. E., Twohig, M. P., Rosenfield, D., Hayes, S. C., & Craske, M. G. (2012) · Cognitive and Behavioral Practice · doi:10.1016/j.cbpra.2012.05.004 · Cited by 56 · see citing works
“While some of these studies purposefully exclude exposure exercises for experimental reasons (Codd et al., 2011; Twohig, Hayes, &Masuda, 2006; Twohig et al., 2010), ACT is complementary to traditional exposure exercises.”
BackgroundSelf-citationMoritz, S., Fink‐Lamotte, J., Miegel, F. S., Nitsche, K., Kraft, V., Tonn, P., & Jelinek, L. (2018) · Cognitive Therapy and Research · doi:10.1007/s10608-018-9902-0 · Cited by 53 · see citing works
Meditation techniques v . relaxation therapies when treating anxiety: a meta-analytic review
Montero‐Marín, J., García‐Campayo, J., Pérez-Yus, M. C., Zabaleta‐del‐Olmo, E., & Cuijpers, P. J. (2019) · Psychological Medicine · doi:10.1017/s0033291719001600 · Cited by 52 · see citing works
Reid, A. M., Garner, L. E., Van Kirk, N., Gironda, C., Krompinger, J. W., Brennan, B. P., Mathes, B. M., Monaghan, S. C., Tifft, E. D., André, M.-C., et al. (2017) · Depression and Anxiety · doi:10.1002/da.22672 · Cited by 52 · see citing works
“These novel clinical findings align with recent literature suggesting that ACT is an effective treatment for OCD (Twohig et al., 2010) and point to willingness to experience obsessions and anxiety as a potential mechanism of change during exposure therapy.”
ResultYap, K., Mogan, C., & Kyrios, M. (2012) · Journal of Anxiety Disorders · doi:10.1016/j.janxdis.2012.03.002 · Cited by 50 · see citing works
“There is some preliminary evidence that ACT is an effective treatment for OCD (Twohig, Hayes, & Masuda, 2006; Twohig et al., 2010) but further trials are required.”
Wetterneck, C. T., Little, T. E., Rinehart, K. L., Cervantes, M. E., Hyde, E., & Williams, M. T. (2012) · Journal of Obsessive-Compulsive and Related Disorders · doi:10.1016/j.jocrd.2011.12.001 · Cited by 48 · see citing works
Parling, T., Cernvall, M., Ramklint, M., Holmgren, S., & Ghaderi, A. (2016) · BMC Psychiatry · doi:10.1186/s12888-016-0975-6 · Cited by 47 · see citing works
“According to the adherence-rating manual, a rating of 3 indicates “that the variable occurred several times and was covered at least once in a moderately in-depth manner” [32] (see p.”
MethodObsessive-Compulsive and Tic-Related Disorders
Franklin, M. E., Harrison, J. P., & Benavides, K. L. (2012) · Child and Adolescent Psychiatric Clinics of North America · doi:10.1016/j.chc.2012.05.008 · Cited by 41 · see citing works
Angelakis, I., & Pseftogianni, F. (2021) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2021.03.062 · Cited by 47 · see citing works
Iwakabe, S., Nakamura, K., & Thoma, N. C. (2023) · Psychotherapy Research · doi:10.1080/10503307.2023.2183155 · Cited by 54 · see citing works
“Twohig et al. (2010) RCT OCD ACT vs PRT contact with the present moment or mindfulness exercises 8 × 60-min weekly sessions 41 38 AAQ-16 59.76 (11.36) 57.16 (11.67) 73.69 (13.22) 63.81 (7.69) Pre-Post ACT d= 1.06 PRT d= 0.47 3-month 73.37 (14.44) 67.13 (10.74) Pre-3-month ACT d= .86 PRT d= .64 Arch…”
InfluentialMindfulness and acceptance-based behavioral therapies for anxiety disorders.
Roemer, L., Williston, S. K., Eustis, E. H., & Orsillo, S. M. (2013) · Current Psychiatry Reports · doi:10.1007/s11920-013-0410-3 · Cited by 46 · see citing works
“AnRCT found that ACTyielded significantly better outcomes on clinician rated OCD severity than progressive muscle relaxation (PMR) among participants who received a primary diagnosis of OCD, 40 % of whom were taking psychotropic medications and 50 % of whom received at least one additional diagnosis [51].”
BackgroundCourage, self-compassion, and values in Obsessive-Compulsive Disorder
Wetterneck, C. T., Lee, E. B., Smith, A. H., & Hart, J. M. (2013) · Journal of Contextual Behavioral Science · doi:10.1016/j.jcbs.2013.09.002 · Cited by 47 · see citing works
“Acceptance and Commitment Therapy (ACT; Hayes, Strosahl, & Wilson, 1999) is a relatively new form of therapy that has shown promise as an effective treatment for OCD (Twohig et al., 2010).”
BackgroundThompson, B. L., Luoma, J. B., & LeJeune, J. T. (2013) · Journal of Contemporary Psychotherapy · doi:10.1007/s10879-013-9233-0 · Cited by 44 · see citing works
Hayes, S. C., & King, G. A. (2024) · Journal of Contextual Behavioral Science · doi:10.1016/j.jcbs.2024.100809 · Cited by 76 · see citing works
Self-citationMoriana, J. A., Gálvez‐Lara, M., & Corpas, J. (2017) · Clinical Psychology Review · doi:10.1016/j.cpr.2017.03.008 · Cited by 44 · see citing works
Problematic Pornography Use and Mental Health: A Systematic Review
Vieira, C. H., & Griffiths, M. D. (2024) · Sexual Health & Compulsivity · doi:10.1080/26929953.2024.2348624 · Cited by 55 · see citing works
“…coping strategies or experiential avoidance, which concurs with previous studies indicating that experiential avoidance may maintain and/or aggravate compulsive (Twohig et al., 2010), impulsive (Flessner, Busch, Heideman, & Woods, 2008), and addictive behaviors (Stotts, Masuda, & Wilson, 2009).”
Rohani, F., Rasouli‐Azad, M., Twohig, M. P., Ghoreishi, F. S., Lee, E. B., & Akbari, H. (2017) · Journal of Obsessive-Compulsive and Related Disorders · doi:10.1016/j.jocrd.2017.10.002 · Cited by 42 · see citing works
“In the largest western trial of ACT for OCD to date, eight sessions of ACT, without insession exposure exercises, was compared to progressive muscle relaxation (Twohig et al., 2010).”
MethodSelf-citationThe Application of Mindfulness for Interpersonal Dependency: Effects of a Brief Intervention
McClintock, A. S., & Anderson, T. (2013) · Mindfulness · doi:10.1007/s12671-013-0253-3 · Cited by 44 · see citing works
Codd, R. T., Twohig, M. P., Crosby, J. M., & Enno, A. (2011) · Journal of Cognitive Psychotherapy · doi:10.1891/0889-8391.25.3.203 · Cited by 44 · see citing works
“The first author treated all participants and engaged in weekly consultation with the second author, an expert in the use of ACT for anxiety disorders (e.g., Twohig et al., 2010).”
BackgroundResultSelf-citationHinton, M. J., & Gaynor, S. T. (2010) · International Journal of Behavioral Consultation and Therapy · doi:10.1037/h0100906 · Cited by 43 · see citing works
Mindfulness-based Cognitive Therapy for Obsessive-Compulsive Disorder: A Pilot Study.
DIDONNA, F., LANFREDI, M., XODO, E., FERRARI, C., ROSSI, R., & PEDRINI, L. (2019) · Journal of Psychiatric Practice® · doi:10.1097/pra.0000000000000377 · Cited by 43 · see citing works
Soo, C., Tate, R. L., & Lane-Brown, A. (2011) · Brain Impairment · doi:10.1375/brim.12.1.54 · Cited by 42 · see citing works
“The Twohig et al. (2010) study scored 8/10 on the PEDro scale indicating rigorous methodological quality.”
MethodYazıcı, K. U., & Yazıcı, İ. P. (2019) · Nordic Journal of Psychiatry · doi:10.1080/08039488.2019.1652341 · Cited by 41 · see citing works
“Some studies reported that treatment methods that strengthen ER skills may also contribute to the treatment of OCD [38,68].”
BackgroundAcceptance-based exposure therapy for body dysmorphic disorder: A pilot study
Linde, J., Rück, C., Bjureberg, J., Ivanov, V. Z., Djurfeldt, D. R., & Ramnerö, J. (2015) · Behavior Therapy · doi:10.1016/j.beth.2015.05.002 · Cited by 41 · see citing works
“…might be useful in treatment for BDD. Controlled studies have demonstrated the effectiveness of ACT for related disorders such as obsessivecompulsive disorder (OCD), skin picking, and trichotillomania (Twohig et al., 2010; Twohig, Hayes, & Masuda, 2006; Woods, Wetterneck, & Flessner, 2006).”
BackgroundYovel, I., Mor, N., & Shakarov, H. (2014) · Behavior Therapy · doi:10.1016/j.beth.2014.02.007 · Cited by 41 · see citing works
“A thorny issue for studies on ACT treatments (e.g., Twohig et al., 2010) and procedures (e.g., Masuda et al., 2004) is that outcome measurement that is based on aversive internal experiences (e.g., negative mood) is less relevant to this therapy approach, in which functionality and improved valued…”
BackgroundCougle, J. R., & Lee, H. (2013) · Journal of Obsessive-Compulsive and Related Disorders · doi:10.1016/j.jocrd.2013.11.002 · Cited by 40 · see citing works
“Other treatment approaches, including Acceptance and Commitment Therapy, also focus on reducing mental control efforts in OCD and have shown efficacy in treating the disorder (Twohig et al., 2010).”
BackgroundOng, C. W., Barney, J. L., Barrett, T. S., Lee, E. B., Levin, M. E., & Twohig, M. P. (2019) · Journal of Contextual Behavioral Science · doi:10.1016/j.jcbs.2019.06.005 · Cited by 40 · see citing works
Self-citationClarke, S., Kingston, J. L., Wilson, K. G., Bolderston, H., & Remington, B. (2012) · Cognitive and Behavioral Practice · doi:10.1016/j.cbpra.2012.03.001 · Cited by 39 · see citing works
Tracing the roots of mindfulness: Transcendence in Buddhism and Christianity
Trammel, R. C. (2017) · Journal of Religion & Spirituality in Social Work Social Thought · doi:10.1080/15426432.2017.1295822 · Cited by 38 · see citing works
“All these elements of mindfulness can be achieved by being still in a quiet space and by practicing deep breathing, guided imagery, and sensory identification, which are tools also embedded in third-wave behavioral practice interventions: Dialectical Behavioral Therapy, Acceptance and Commitment Therapy, and Mindfulne…”
Tonarelli, S. B., & Pasillas, R. (2016) · Journal of psychiatry · doi:10.4172/2378-5756.1000366 · Cited by 38 · see citing works
“The Society of Clinical Psychology has modest research support based on Chambless criteria [28] of ACT for treatment of depression [17,22], obsessive compulsive disorder [29,30], and mixed anxiety disorders [31].”
MethodAcceptance and commitment group therapy for health anxiety - Results from a pilot study
Eilenberg, T., Kronstrand, L., Fink, P., & Frostholm, L. (2013) · Journal of Anxiety Disorders · doi:10.1016/j.janxdis.2013.06.001 · Cited by 38 · see citing works
Samuel, S. R., Gururaj, R., Kumar, V., Vira, P., Saxena, P. P., & Keogh, J. (2020) · Journal of Cancer Survivorship · doi:10.1007/s11764-020-00972-x · Cited by 40 · see citing works
Thompson, B. L., Twohig, M. P., & Luoma, J. B. (2020) · Behavior Therapy · doi:10.1016/j.beth.2020.04.011 · Cited by 37 · see citing works
Self-citationVakili, Y., Gharaee, B., & Habibi, M. (2015) · Iranian Journal of Psychiatry and Behavioral Sciences · doi:10.17795/ijpbs845 · Cited by 37 · see citing works
- Authors
- Twohig, M. P., Hayes, S. C., Plumb, J. C., Pruitt, L. D., Collins, A. B., Hazlett-Stevens, H., & Woidneck, M. R.
- Affiliations
- Utah State University (US)
- University of Nevada, Reno (US)
- Venue
- Journal of Consulting and Clinical Psychology
- Published
- 2010-10
- Volume
- 78
- Issue
- 5
- Pages
- 705-716
- ISSN
- 0022-006X (ISSN-L)
- 1939-2117
- PMC
- PMC2948415
- OpenAlex
- W2132781604
- Cited by
- 434
- References
- 49
- Citations by year
- 2026: 16 · 2025: 39 · 2024: 26 · 2023: 31 · 2022: 24 · 2021: 27 · 2020: 17 · 2019: 31 · 2018: 25 · 2017: 33 · 2016: 16 · 2015: 25 · 2014: 32 · 2013: 31 · 2012: 38
- FWCI
- 31.17
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Journal of Consulting and Clinical Psychology (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Digital Commons - USU (Utah State University) (submittedVersion)
- Funders
- National Institute of Mental Health (R21 MH074968)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Obsessive-Compulsive Spectrum Disorders
- Social Sciences › Psychology › Clinical Psychology › Mindfulness and Compassion Interventions
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Keywords
- obsessive-compulsive disorder, acceptance and commitment therapy, progressive muscle relaxation, cognitive behavioral therapy, depression, quality of life, thought-action fusion, thought control, treatment refusal, dropout
- MeSH terms
- Adaptation, Psychological, Adolescent, Adult, Aged, Anxiety, Awareness, Depressive Disorder, Fear, Female, Follow-Up Studies, Humans, Implosive Therapy, Male, Middle Aged, Obsessive-Compulsive Disorder, Personality Inventory, Psychometrics, Quality of Life, Relaxation Therapy, Reproducibility of Results, Comorbidity, Young Adult
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