Cited by 80Obsessive-Compulsive Spectrum DisordersAnxiety, Depression, Psychometrics, Treatment, Cognitive ProcessesPsychoanalysis and Psychopathology Research

An update on the efficacy of psychological treatments for obsessive-compulsive disorder in adults

Open access
Ponniah, Kathryn, Magiati, Iliana, Hollon, Steven D.·2013·Journal of Obsessive-Compulsive and Related Disorders

Abstract

We conducted a review to provide an update on the efficacy of psychological treatments for OCD in general and with regard to specific symptom presentations. The PubMed and PsycINFO databases were searched for randomized controlled trials (RCTs) published up to mid February 2012. Forty-five such studies were identified. Exposure and response prevention (ERP) and cognitive-behavioral therapy (CBT) were found to be efficacious and specific for OCD. More purely cognitive interventions that did not include ERP or behavioral experiments were found to be possibly efficacious, as were Acceptance and Commitment Therapy, Motivational Interviewing as an adjunct to the established treatments, Eye Movement Desensitization and Reprocessing, and Satiation Therapy. There was little support for Stress Management or Psychodynamic Therapy. Although the majority of the studies recruited mixed or unspecified samples of patients and did not test for moderation, CBT was efficacious for obsessional patients who lacked overt rituals. One more purely cognitive intervention named Danger Ideation Reduction Therapy was found to be possibly efficacious for patients with contamination obsessions and washing compulsions. Although ERP and CBT are the best established psychological treatments for OCD, further research is needed to help elucidate which treatments are most effective for different OCD presentations. © 2013 Elsevier Ltd.

AI snapshot

Written from the paper’s full text.

TL;DR

This review updated the evidence on psychological treatments for adult OCD by examining 45 randomized controlled trials published through mid-February 2012. It found that exposure and response prevention and cognitive-behavioral therapy have the strongest support, while several newer or purely cognitive approaches remain only tentatively supported and subtype-specific evidence is sparse.

Key findings

Across 45 RCTs, ERP was tested in 31 trials and CBT in 18; ERP outperformed waitlist controls in all five comparisons and also beat anxiety management, progressive muscle relaxation, stress management, and autogenic training in cited trials, though only about half of ERP-treated patients showed clinically significant improvement and full remission was rarer. CBT also outperformed waitlist controls in every relevant trial and was judged to have strong support, including for patients with obsessions but no overt rituals; comparisons with ERP generally showed no differences, though one trial favored ERP and one favored CBT under self-guided exposure. ACT was tentatively supported after one trial, with 46% of ACT patients versus 13% of progressive muscle relaxation patients achieving clinically significant change. Satiation therapy, EMDR, motivational interviewing as an adjunct, and purely cognitive approaches including DIRT were classified as only tentatively supported, with DIRT showing promise for contamination/washing symptoms; stress management and psychodynamic therapy had little support.

Methods

Searched PubMed and PsycINFO through February 14, 2012; PubMed yielded 612 papers and PsycINFO 667, with 71 included papers grouped into 45 RCTs, plus one added paper for a total of 72 papers. Inclusion required adults with a formal OCD diagnosis, random assignment, a clear treatment description, outcome data, and peer-reviewed publication. Treatments were classified as behavioral (ERP, satiation, ACT), CBT, purely cognitive, stress management, or other (MI, EMDR, psychodynamic), and support was rated using Chambless and Hollon criteria with quality assessed via Cuijpers et al. criteria.

Limitations

The authors note that study quality varied widely: the mean quality rating was 4.6 out of 8 (SD 2.2), although post-2005 trials averaged 5.7 versus 3.9 for earlier trials. Few trials tested specific OCD subtypes or moderation, and few RCTs examined psychodynamic therapy or other interventions, limiting conclusions. Evident from the text: several conclusions rest on single trials (ACT, satiation, EMDR, psychodynamic), stress management lacked no-treatment controls for absolute efficacy, and the satiation trial had unusually high baseline and low post-treatment YBOCS scores with an unclear procedure.

Model-written summary. Check it against the paper before relying on it.

Integrity signals

Registry

Crossref · 10.1016/j.jocrd.2013.02.005

Cites

157 of 157 references verified0 citation errors · 0 not checkable

Statistics

Nothing to recompute.

Claims the paper makes

17 of 124 cited sources checked · 12 supported · 1 flagged · accuracy not yet measured

  • Premisecitation

    Comorbidity can contribute to poorer ERP outcome in medicated patients.

    “Given that comorbidity can contribute to poorer ERP outcome in medicated patients (Maher et al., 2010; Pinto et al., 2011)”
    Quote in the paperNot a substantial claim2 of 2 sources checked
    • cites Maher et al., 2010 source
      Experimental — accuracy not yet measured
    • cites Pinto et al., 2011 source
  • Findingcitation

    ERP enhanced response to serotonergic medication when added for patients who had already partially responded to these agents.

    “ERP enhanced response to serotonergic medication when it was added for patients who had already partially responded to these agents (Tenneij et al., 2005).”
    Quote in the paperSubstantial claim1 of 1 sources checked
    • cites Tenneij et al., 2005 source
  • Findingcitation

    ACT may be designated as possibly efficacious in treatment of OCD.

    “ACT may therefore be designated as possibly efficacious in the treatment of OCD.”
    Quote in the paperSubstantial claim1 of 1 sources checked
    • cites Twohig et al., 2010 source
  • Findingcitation

    ACT led to significantly greater reductions in OCD symptoms than PMR.

    “ACT led to significantly greater reductions in OCD symptoms than PMR”
    Quote in the paperSubstantial claim1 of 1 sources checked
    • cites Twohig et al., 2010 source
  • Findingcitation

    At end of treatment, 46% of ACT patients achieved clinically significant change compared to 13% in PMR.

    “at the end of treatment 46% of the ACT patients had achieved clinically significant change compared to 13% in PMR”
    Quote in the paperSubstantial claim1 of 1 sources checked
    • cites Twohig et al., 2010 source
  • May combine two claims. 54
  • Classified as probably not a substantial claim. 19
  • May combine two claims.

    Premisecitation

    OCD is best conceptualized as a dimensional disorder with at least five consistently identified symptom dimensions.

    “Given the wide variation in the presentation of OCD, there is increasing evidence that it may be best conceptualized as a dimensional disorder and the following symptom dimensions have been most consistently identified: (a) contamination obsessions with cleaning/washing rituals, (b) doubts about harm with checking/reassurance seeking rituals, (c) obsessions relating to a need for symmetry, exactn”
    Quote in the paperNot a substantial claim1 of 3 sources checked
    • cites Abramowitz et al., 2010 source
    • cites Bloch et al., 2008 source

      The Discussion supports a dimensional approach, but identifies a fairly robust four-factor structure—not at least five consistently identified dimensions. It recommends specifying those four dimensions: symmetry, forbidden thoughts, cleaning, and hoarding. (LLM, conf=0.88)

      Checked by a reasoning model — may be wrong.

      Experimental — accuracy not yet measured
    • cites Mataix-Cols et al., 2005 source
  • May combine two claims.

    Interpretationcitation

    The only trial finding an advantage for CBT over ERP used a version of self-guided exposure, which might have diluted its efficacy.

    “It is also noteworthy that the only trial to find an advantage for CBT over ERP used a version of self-guided exposure (van Oppen et al., 1995), which might have diluted its efficacy.”
    Quote in the paperNot a substantial claim1 of 1 sources checked
    • cites van Oppen et al., 1995 source
  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Premisecitation

    Several studies have shown associations between OCD and cognitive variables including inflated responsibility, threat perceptions, lowered memory confidence, difficulty tolerating uncertainty, perfectionism, thought-action fusion, and over-importance/need to control thoughts.

    “Several studies have shown associations between OCD and cognitive variables including inflated responsibility and threat perceptions, lowered confidence in memory, difficulty tolerating uncertainty, perfectionism, thought-action fusion, and the over-importance of and need to control thoughts (e.g. Abramowitz et al., 2006; Moore & Abramowitz, 2007; Rassin et al., 2000; Salkovskis et al., 2000; Shaf”
    Quote in the paperNot a substantial claim1 of 3 sources checked
    • cites Abramowitz et al., 2006 source
    • cites Moore & Abramowitz, 2007 source
    • cites Rassin et al., 2000 source

      The Discussion reports correlations between thought-action fusion, thought suppression, and obsessive–compulsive symptom scores. This supports citing the study for those cognitive associations, but its participants were undergraduate students, so it does not establish associations in people diagnosed with OCD; it also does not test every variable in the citing sentence. (LLM, conf=0.85)

      Experimental — accuracy not yet measured
  • May combine two claims.

    Study design and conductcitation

    Many ERP trials used the Yale-Brown Obsessive-Compulsive Scale as an outcome measure, which is viewed as the gold standard for OCD symptom severity.

    “A strength of many ERP trials was the use of the Yale-Brown Obsessive-Compulsive Scale (YBOCS; Goodman, Price et al, 1989 a; b) as an outcome measure. This clinician-administered tool is viewed as the gold standard for ascertaining OCD symptom severity (Abramowitz, 2006; Summerfeldt, 2001).”
    Quote in the paperNot a substantial claim1 of 3 sources checked
    • cites Goodman, Price et al, 1989 a; b

      Couldn’t be matched to a paper in Crossref, so it can’t be checked.

    • cites Abramowitz, 2006 source
    • cites Summerfeldt, 2001

      Couldn’t be matched to a paper in Crossref, so it can’t be checked.

  • May combine two claims.

    Findingcitation

    Standard ERP and a less expensive stepped care approach were similarly efficacious, and 28% of patients who started stepped care responded to the low intensity intervention.

    “A comparison of standard ERP to a less expensive stepped care approach found that these approaches were similarly efficacious, and 28% of patients who started stepped care responded to the low intensity intervention (Tolin et al., 2011).”
    Quote in the paperSubstantial claim1 of 1 sources checked
    • cites Tolin et al., 2011 source

      The Results > Efficacy section reports no apparent efficacy difference between stepped care and standard ERP, and Abstract > Results reports significantly lower costs for stepped care. Method > Procedure describes the low-intensity first step and its responder criterion, but the passages available from our copy do not establish that 28% of patients who started stepped care responded to that step. (LLM, conf=0.84)

      Experimental — accuracy not yet measured
  • May combine two claims.

    Findingcitation

    There were no significant differences in outcome between CBT and fluoxetine, but comorbidity reduced magnitude of response.

    “There were no significant differences in outcome between treatments, but comorbidity reduced the magnitude of response.”
    Quote in the paperSubstantial claim1 of 2 sources checked
    • cites Belotto-Silva et al., 2012 source
    • cites Hoexter et al., 2012 source

      The Treatment Outcome section reports no statistical difference in OCD symptom reduction between fluoxetine and CBT. The Methodological Considerations and Conclusions section says comorbidities may have added variability to the findings, but does not say they reduced the magnitude of treatment response. Page numbers were not provided in our copy. (LLM, conf=0.88)

      Experimental — accuracy not yet measured
  • May combine two claims.

    Premisecitation

    Hoarding may respond less well to treatment than other types of OCD, leading to development of type of CBT that appears specifically efficacious for hoarding problems.

    “For example, hoarding may respond less well to treatment than other types of OCD (Abramowitz et al., 2003; Rufer et al., 2006), leading to the development of a type of CBT that appears to be specifically efficacious for hoarding problems (Steketee et al., 2010).”
    Quote in the paperNot a substantial claim1 of 3 sources checked
    • cites Abramowitz et al., 2003 source
    • cites Rufer et al., 2006 source
    • cites Steketee et al., 2010 source
  • May combine two claims.

    Findingcitation

    Although comorbidity may lead to poorer ERP or CBT outcome, patients with more complex presentations may still benefit from established OCD treatments either in isolation or integrated with other interventions.

    “Finally, although comorbidity may lead to a poorer ERP or CBT outcome (Belotto-Silva et al., 2012; Maher et al., 2010; Pinto et al., 2011), patients with more complex presentations may still benefit from established OCD treatments either in isolation or integrated with other interventions (Belotto-Silva et al., 2012; Fals-Stewart & Schafer, 1992; Rector et al., 2009).”
    Quote in the paperSubstantial claim2 of 3 sources checked
    • cites Belotto-Silva et al., 2012 source
    • cites Maher et al., 2010 source
    • cites Pinto et al., 2011 source
  • May combine two claims.

    Findingcitation

    Adding ERP to standard substance use treatment in a therapeutic community was superior to adding Progressive Muscle Relaxation or no other intervention on OCD symptom reduction, length of time in treatment, and substance use relapse rate after discharge in comorbid patients.

    “One study found that adding ERP to standard substance use treatment provided in a therapeutic community was superior to adding Progressive Muscle Relaxation or no other intervention on OCD symptom reduction, the length of time in treatment and the rate of substance use relapse following discharge in comorbid patients (Fals-Stewart & Schafer, 1992).”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites Fals-Stewart & Schafer, 1992 source
  • May combine two claims.

    Findingcitation

    ERP was superior to CBT in one study and did not differ in five others, although several of these studies had relatively small samples.

    “It was superior to CBT in one study (McLean et al., 2001) and did not differ in five others (Cottraux et al., 2001; Emmelkamp & Beens, 1991; O’Connor et al., 2005; Vogel et al., 2004; Whittal et al., 2005), although in a number of these studies, the sample sizes were relatively small.”
    Quote in the paperSubstantial claim0 of 3 sources checked
    • cites McLean et al., 2001 source
    • cites Cottraux et al., 2001 source
    • cites Emmelkamp & Beens, 1991 source
  • May combine two claims.

    Findingcitation

    Only about half of all treated patients show clinically significant change with ERP, and fewer still show full remission.

    “Only about half of all treated patients show clinically significant change with ERP (Abramowitz, 1998), and fewer still show full remission (Belloch et al., 2008; McLean et al., 2001; Simpson et al., 2006; Simpson et al., 2010; van Oppen et al., 2010; Vogel et al., 2004; Whittal et al., 2005).”
    Quote in the paperSubstantial claim0 of 3 sources checked
    • cites Abramowitz, 1998 source
    • cites Belloch et al., 2008 source
    • cites McLean et al., 2001 source
  • May combine two claims.

    Findingcitation

    ERP was superior to clomipramine and to a pill-placebo.

    “ERP was superior to clomipramine and to a pill-placebo (Foa et al., 2005)”
    Quote in the paperSubstantial claim0 of 1 sources checked
    • cites Foa et al., 2005 source
  • May combine two claims.

    Findingcitation

    ERP was superior to Anxiety Management, Progressive Muscle Relaxation, Stress Management combined with medication, and Autogenic Training combined with pill-placebo.

    “It also was superior to Anxiety Management (Lindsay et al., 1997) and Progressive Muscle Relaxation (see Fals-Stewart et al., 1993; Greist et al., 2002; Marks et al., 2000), as well as Stress Management when each was combined with medication (Simpson et al., 2008b) and to Autogenic Training when each was combined with pill-placebo (Nakatani et al., 2005).”
    Quote in the paperSubstantial claim0 of 3 sources checked
    • cites Lindsay et al., 1997 source
    • cites Fals-Stewart et al., 1993 source
    • cites Simpson et al., 2008b

      Couldn’t be matched to a paper in Crossref, so it can’t be checked.

  • May combine two claims.

    Findingcitation

    ERP combined with medication was more efficacious than medication alone or medication plus anti-exposure instructions, but not more efficacious than ERP alone.

    “ERP combined with medication was also more efficacious than either medication alone (Foa et al., 2005) or medication plus anti-exposure instructions (Marks et al., 1988), but not more efficacious than ERP alone (de Haan et al., 1997; Foa et al., 2005; van Balkom et al., 1998).”
    Quote in the paperSubstantial claim0 of 3 sources checked
    • cites Foa et al., 2005 source
    • cites Marks et al., 1988 source
    • cites de Haan et al., 1997 source
  • May combine two claims.

    Findingnone given

    The majority of studies recruited mixed or unspecified patient samples and did not test for moderation.

    “Although the majority of the studies recruited mixed or unspecified samples of patients and did not test for moderation”
    Quote in the paperSubstantial claim
  • May combine two claims.

    Findingown data

    ERP was evaluated in 31 trials, CBT in 18, purely cognitive interventions in 4, ACT and Satiation Therapy once each, Stress Management in 9, Motivational Interviewing twice, and Psychodynamic Therapy and EMDR once each.

    “ERP was evaluated in the largest number of trials (N=31), with CBT second (N=18). More purely cognitive interventions were evaluated in a handful of trials (N=4) and the newer behavioral interventions—ACT and Satiation Therapy—once each (N’s=1). Stress Management was tested in several trials, but almost always as the control treatment in comparison to other preferred alternatives (N=9). MI was”
    Quote in the paperNot a substantial claim
  • May combine two claims.

    Findingown data

    Exposure and response prevention and cognitive-behavioral therapy are efficacious and specific for obsessive-compulsive disorder.

    “Exposure and response prevention (ERP) and cognitive-behavioral therapy (CBT) were found to be efficacious and specific for OCD.”
    • Also stated in: § Behavioral Interventions · hedged
      “This indicates that ERP is efficacious and specific in the treatment of OCD.”
    Quote in the paperSubstantial claim
  • May combine two claims.

    Findingown data

    Only a few studies investigated treatment effects on specific OCD subtypes: contamination obsessions and washing compulsions in 2 studies and obsessions without overt compulsions in 3 studies.

    “Only a few studies investigated the effects of treatment on specific OCD subtypes, including contamination obsessions and washing compulsions (N=2) and obsessions without overt compulsions (N=3).”
    Quote in the paperNot a substantial claim
  • May combine two claims.

    Findingreasoning

    On the whole, there is little clear evidence that either CBT or ERP modality is superior to the other, although ERP may be easier to learn and better suited to group format.

    “On the whole, there is little clear evidence that either modality is superior to the other, although ERP may be easier to learn and better suited to a group format.”
    Quote in the paperSubstantial claim
  • May combine two claims.

    Findingcitation

    In the only study of satiation therapy, it was comparable to conventional ERP, both were superior to a wait list condition, and these advantages were maintained at six-month follow-up.

    “In the only study to examine satiation therapy, Khodarahimi (2009) found that it was comparable to conventional ERP; and both treatments were superior to a wait list condition. These advantages were also maintained at six-month follow-up.”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites Khodarahimi (2009) source
  • Classified as probably not a substantial claim. May combine two claims.

    Findingreasoning

    That one study is enough to earn more generic cognitive interventions designation of possibly efficacious, but this was not a particularly impressive set of studies.

    “Although that one study is enough to earn the more generic cognitive interventions the designation of possibly efficacious, this was not a particularly impressive set of studies.”
    Quote in the paperSubstantial claim
  • May combine two claims.

    Findingcitation

    Computer-guided ERP (BT Steps) was less efficacious than therapist-guided ERP but more efficacious than relaxation training in reducing OCD symptoms.

    “Computer-guided ERP (BT Steps) was less efficacious than a more expensive therapist-guided ERP, but more efficacious in reducing OCD symptoms than was relaxation training (Greist et al., 2002).”
    Quote in the paperSubstantial claim0 of 1 sources checked
    • cites Greist et al., 2002 source
  • May combine two claims.

    Findingcitation

    CBT is efficacious and specific in treatment of OCD.

    “we conclude that CBT is efficacious and specific in the treatment of OCD.”
    Quote in the paperSubstantial claim0 of 1 sources checked
    • cites Whittal et al., 2010 source
  • May combine two claims.

    Findingreasoning

    Satiation Therapy meets criteria for possibly efficacious treatment based on a single study, but the designation is tenuous due to methodological shortcomings.

    “On the basis of this single study, Satiation Therapy meets the criteria for a possibly efficacious treatment, but this designation is tenuous given the methodological shortcomings noted above.”
    Quote in the paperSubstantial claim
  • May combine two claims.

    Findingreasoning

    Few early studies found differences and are of interest only because ERP was not so powerful that it separated from these approaches.

    “As might be expected, few found differences and are of interest only because ERP was not so powerful that it separated from these approaches.”
    Quote in the paperNot a substantial claim
  • May combine two claims.

    Findingcitation

    One study found CBT superior to sertraline in reducing OCD symptoms, but medication dosage was low and most differences were non-significant trends.

    “One study found CBT superior to sertraline in reducing OCD symptoms, but the medication dosage was low (100 mg/day) and most of the differences between treatment effects were non-significant trends (Sousa et al., 2006).”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites Sousa et al., 2006 source
  • May combine two claims.

    Findingreasoning

    CBT has fared well relative to medication treatment, although evidence is not as compelling as for ERP.

    “CBT also has fared well relative to medication treatment, although the evidence is not as compelling as it is for ERP.”
    Quote in the paperSubstantial claim
  • May combine two claims.

    Findingcitation

    Involving the family in ERP treatment led to greater OCD symptom reduction and greater amelioration of impairment in work and family domains in one study.

    “Involving the family in ERP treatment led to greater OCD symptom reduction and greater amelioration of impairment in work and family domains in one study (Mehta, 1990), although van Oppen et al. (2010) found no differences in outcome between self-conducted versus therapist-assisted ERP, regardless of whether experienced or student therapists were used.”
    Quote in the paperNot a substantial claim0 of 2 sources checked
    • cites Mehta, 1990 source
    • cites van Oppen et al. (2010) source
  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Findingnone given

    None of the patients in the satiation therapy study reported comorbid psychiatric diagnoses.

    “Similarly, none of the patients in this study reported comorbid psychiatric diagnoses.”
    Quote in the paperNot a substantial claim
  • May combine two claims.

    Findingown data

    DIRT showed promise and appeared possibly efficacious in treatment of patients with fears of contamination, but effects require replication by other groups.

    “DIRT showed promise and appeared to be possibly efficacious in the treatment of patients with fears of contamination, but the effects of DIRT require replication by groups other than that which developed the treatment.”
    Quote in the paperSubstantial claim
  • May combine two claims.

    Findingown data

    Mean YBOCS scores at pre-treatment in the satiation therapy study were considerably higher than reported in most trials, and post-treatment scores were well below typical OCD treatment studies.

    “Mean YBOCS scores at pre-treatment were considerably higher (M = 37.10 for satiation therapy and 37.20 for ERP out of a possible 40) than is reported in most trials (mid to late 20’s); and the post-treatment YBOCS scores (M = 6.40 for satiation therapy and 5.58 for ERP) were well below what typically is observed in most OCD treatment studies (low double digits).”
    Quote in the paperSubstantial claim
  • May combine two claims.

    Findingown data

    Two studies evaluated efficacy of adding MI to cognitive and behavioral treatments, with mixed results.

    “Two studies have evaluated the efficacy of adding MI to cognitive and behavioral treatments, with mixed results.”
    Quote in the paperNot a substantial claim
  • May combine two claims.

    Findingnone given

    Most studies comparing ERP and CBT found comparable efficacy, and those few differences found can be attributed plausibly to variability in how treatments were implemented.

    “Most studies comparing the two found comparable efficacy, and those few differences that were found can be attributed plausibly to variability in how the treatments were implemented.”
    Quote in the paperSubstantial claim
  • May combine two claims.

    Findingcitation

    This one study is sufficient to state that Stress Management is possibly efficacious in treatment of obsessional patients, but outcomes across studies generally have been unimpressive.

    “This one study is sufficient to state that Stress Management is possibly efficacious in the treatment of obsessional patients, but outcomes across studies generally have been unimpressive.”
    Quote in the paperSubstantial claim0 of 1 sources checked
    • cites Whittal et al., 2010 source
  • May combine two claims.

    Findingcitation

    ERP has consistently been found efficacious and specific, whereas CBT has gained this status only in last decade.

    “ERP has consistently been found to be efficacious and specific, whereas CBT has gained this status only in the last decade (DeRubeis & Crits-Christoph, 1998; Roth & Fonagy, 2005).”
    Quote in the paperNot a substantial claim0 of 2 sources checked
    • cites DeRubeis & Crits-Christoph, 1998 source
    • cites Roth & Fonagy, 2005

      Couldn’t be matched to a paper in Crossref, so it can’t be checked.

  • May combine two claims.

    Findingreasoning

    Adding MI to behavioral and cognitive treatments to enhance readiness to change in OCD patients can be said to be possibly efficacious, but not yet established.

    “Accordingly, adding MI to behavioral and cognitive treatments to enhance readiness to change in OCD patients can be said to be possibly efficacious, but not yet established.”
    Quote in the paperSubstantial claim
  • May combine two claims.

    Findingown data

    We rated each study on eight criteria developed by Cuijpers and colleagues (2010) and found mean quality rating for all RCTs included in this review was only 4.6 (SD 2.2) out of maximum 8.0.

    “We rated each study on eight criteria developed by Cuijpers and colleagues (2010) and found that the mean quality rating for all RCTs included in this review was only 4.6 (SD 2.2) out of a maximum of 8.0.”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites Cuijpers et al., 2010 source
  • May combine two claims.

    Findingreasoning

    Based on findings of single studies in each instance (with one supporting ACT being most methodologically sound), ACT, EMDR, and satiation therapy can be said to be possibly efficacious.

    “Based on the findings of single studies in each instance (with the one supporting ACT being the most methodologically sound), these treatments can be said to be possibly efficacious.”
    Quote in the paperSubstantial claim
  • May combine two claims.

    Findingcitation

    EMDR outperformed citalopram in symptom reduction, but doses were less than adequate.

    “Although EMDR outperformed citalopram in symptom reduction, doses were less than adequate.”
    Quote in the paperSubstantial claim0 of 1 sources checked
    • cites Nazari et al., 2011 source
  • Probably not a substantial claim: may not pass S2 (checkable).

    Findingreasoning

    Replication by other research groups is required before firm conclusions can be drawn regarding efficacy of each.

    “Replication by other research groups, however, is required before firm conclusions can be drawn regarding the efficacy of each.”
    Quote in the paperNot a substantial claim
  • Classified as probably not a substantial claim.

    Findingnone given

    Our review extends earlier reviews by applying criteria developed by Chambless and Hollon (1998) to more recently tested therapies and treatment of specific OCD presentations.

    “Our review extends these earlier reviews by applying the criteria developed by Chambless and Hollon (1998) to more recently tested therapies and the treatment of specific OCD presentations.”
    Quote in the paperSubstantial claim0 of 1 sources checked
    • cites Chambless and Hollon, 1998

      Couldn’t be matched to a paper in Crossref, so it can’t be checked.

  • May combine two claims.

    Findingreasoning

    While both ERP and CBT are efficacious and specific in treatment of OCD, it remains unclear whether adding cognitive restructuring enhances efficacy of more purely behavioral interventions.

    “While both ERP and CBT are efficacious and specific in the treatment of OCD, it remains unclear whether adding cognitive restructuring enhances the efficacy of more purely behavioral interventions.”
    Quote in the paperSubstantial claim
  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Findingnone given

    One difference between ERP and satiation therapy is that latter can include instructions to repeatedly engage in compulsive behaviors.

    “One difference between ERP and satiation therapy, however, is that the latter can include instructions to repeatedly engage in compulsive behaviors.”
    Quote in the paperNot a substantial claim
  • Probably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.

    Premisecitation

    There is too much overlap among treatment elements to define ERP as purely behavioral and cognitive therapy as purely cognitive; their differences are best conceptualized as a matter of emphasis and focus.

    “Abramowitz et al. (2005) have argued that there is too much overlap among treatment elements to define ERP as “purely” behavioral and cognitive therapy as “purely” cognitive, and have suggested that it may be best to conceptualize their differences as a matter of emphasis and focus, with cognitive interventions focusing more on cognitive elements and behavioral (ERP) devoting more attention to”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites Abramowitz et al., 2005 source
  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Premisecitation

    ERP protocols often include cognitive procedures.

    “Although originally derived from learning theory, ERP protocols often include cognitive procedures.”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites Foa et al., 2005 source
  • May combine two claims.

    Premisecitation

    OCD remains one of the most refractory non-psychotic disorders, and few patients end treatment completely symptom free.

    “Still, ERP is no panacea. OCD remains one of the most refractory of the non-psychotic disorders and few patients end treatment completely symptom free (Abramowitz, 1998).”
    Quote in the paperSubstantial claim0 of 1 sources checked
    • cites Abramowitz, 1998 source
  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Study design and conductown data

    Therapist training, experience, and supervision varied across ERP studies.

    “The training, experience, and supervision of study therapists varied as well.”
    Quote in the paperNot a substantial claim
  • May combine two claims.

    Study design and conductreasoning

    There was considerable variability in how ERP was implemented across studies, which affects interpretation of the results.

    “That being said, there was considerable variability in the way ERP was implemented across the studies, which affects interpretation of the results.”
    Quote in the paperNot a substantial claim
  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Study design and conductcitation

    Some studies did not provide information on therapist training and supervision.

    “Moreover, some studies did not provide information on therapist training and supervision (e.g. Marks et al., 1988).”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites Marks et al., 1988 source
  • Probably not a substantial claim: may not pass S2 (checkable), S3 (load-bearing).

    Study design and conductnone given

    Greater weight can be given to studies that employed independent assessors for YBOCS administration.

    “Moreover, even greater weight can be given to those studies that employed independent assessors for YBOCS administration (e.g. Foa et al., 2005).”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites Foa et al., 2005 source
  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Study design and conductcitation

    The quality of included studies was considered using criteria derived by Cuijpers et al. from work by others.

    “The quality of the included studies was considered using in part the criteria derived by Cuijpers et al. (2010) from work by others (Chambless & Hollon, 1998; Higgins & Green, 2006).”
    Quote in the paperNot a substantial claim0 of 3 sources checked
    • cites Cuijpers et al. (2010) source
    • cites Chambless & Hollon, 1998

      Couldn’t be matched to a paper in Crossref, so it can’t be checked.

    • cites Higgins & Green, 2006

      Couldn’t be matched to a paper in Crossref, so it can’t be checked.

  • May combine two claims.

    Premisecitation

    Further analysis found evidence of moderation: patients with more severe symptoms responded better to CBT, whereas patients with milder symptoms showed greater change following Stress Management.

    “further analysis of the data from that trial found evidence of moderation in that patients who suffered from more severe symptoms responded better to CBT, whereas patients with milder symptoms showed greater change following Stress Management (Woody et al., 2011).”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites Woody et al., 2011 source
  • May combine two claims.

    Interpretationreasoning

    This suggests CBT may have an enduring effect similar to that found for ERP, but conclusion is less compelling due to absence of comparison to medication withdrawal.

    “While this suggests that CBT may have an enduring effect similar to that found for ERP, this conclusion is made less compelling by the absence of any comparison to medication withdrawal (see Simpson et al., 2004, with respect to ERP).”
    Quote in the paperSubstantial claim0 of 1 sources checked
    • cites Simpson et al., 2004 source
  • May combine two claims.

    Premisecitation

    Stress Management in Whittal et al. (2010) study produced very good results and was almost as effective as CBT.

    “Stress Management in the Whittal et al. (2010) study produced very good results and was almost as effective as CBT.”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites Whittal et al., 2010 source
  • May combine two claims.

    Study design and conductreasoning

    The conclusion that CBT is efficacious and specific is based on fewer studies than was case for ERP.

    “This conclusion, however, is based on fewer studies than was the case for ERP.”
    Quote in the paperNot a substantial claim
  • Classified as probably not a substantial claim. May combine two claims.

    Study design and conductreasoning

    It is unclear whether patients in the satiation therapy study were asked to increase frequency of compulsive behaviors and whether they succeeded.

    “Thus, it is not clear whether the patients were asked to increase the frequency of their compulsive behaviors and, if so, whether they succeeded.”
    Quote in the paperSubstantial claim
  • Probably not a substantial claim: may not pass S1 (asserted), S3 (load-bearing).

    Premisecitation

    Training clinicians in ERP is easier than training them in CBT for OCD.

    “It has been argued that training clinicians in ERP is easier than training them in CBT for OCD (McLean et al., 2001), and the same has been said with respect to behavioral activation relative to cognitive therapy (a cognitive-behavioral intervention) for depression (Coffman et al., 2007).”
    Quote in the paperNot a substantial claim0 of 2 sources checked
    • cites McLean et al., 2001 source
    • cites Coffman et al., 2007 source
  • May combine two claims.

    Study design and conductcitation

    Early studies used generic cognitive approaches that did not specifically target obsessional thinking, with small samples and less experienced graduate students often delivering treatments.

    “Early studies used generic cognitive approaches that did not specifically target obsessional thinking. Sample sizes were small and less experienced graduate students often delivered the treatments (e.g., Emmelkamp et al., 1988).”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites Emmelkamp et al., 1988 source
  • Probably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.

    Interpretationreasoning

    If YBOCS scores mean the same thing in this trial as in other studies, then this was the most severe OCD sample and the most efficacious interventions.

    “If scores on the YBOCS mean the same thing in this trial that they do in other studies, then this was not only the most severe OCD sample studied in the literature, but also the most efficacious interventions.”
    Quote in the paperNot a substantial claim
  • May combine two claims.

    Interpretationreasoning

    Differences between therapist-guided and computer-guided ERP were no longer significant when only patients who had completed at least one self-exposure homework session were considered, suggesting that the major benefit of a therapist is to increase the likelihood that the patient engages in exposure.

    “Differences between therapist-guided and computer-guided ERP were no longer significant when only the patients who had completed one or more sessions of self-exposure for homework were considered, suggesting that the major benefit of having a therapist is to increase the likelihood that the patient will engage in the exposure process.”
    Quote in the paperSubstantial claim
  • May combine two claims.

    Premisecitation

    Over half of these patients achieved full remission at end of treatment compared to about a third in control condition; difference both large and significant.

    “Over half of these patients had achieved full remission at the end of treatment compared to about a third in the control condition; a difference which was both large and significant.”
    Quote in the paperSubstantial claim0 of 1 sources checked
    • cites Meyer et al., 2010a

      Couldn’t be matched to a paper in Crossref, so it can’t be checked.

  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Interpretationcitation

    From theoretical perspective, it is possible that reason both ERP and CBT are efficacious and specific in treatment of OCD is because both address same maintaining factors, such as maladaptive beliefs, neutralizing strategies, and avoidance.

    “From a theoretical perspective, it is possible that the reason both ERP and CBT are efficacious and specific in the treatment of OCD is because both address the same maintaining factors, such as maladaptive beliefs (e.g., inflated responsibility), neutralizing strategies (e.g., reassurance seeking and rituals), and avoidance (Salkovskis, 1999; Rachman, 1971; 1997; 1998).”
    Quote in the paperNot a substantial claim0 of 3 sources checked
    • cites Salkovskis, 1999 source
    • cites Rachman, 1971 source
    • cites Rachman, 1997 source
  • May combine two claims.

    Premisecitation

    A Canadian study found Stress Management superior to wait list control for patients without overt compulsions, but less efficacious than CBT.

    “A Canadian study found Stress Management superior to a wait list control for patients without overt compulsions (the only study in which they were compared), but less efficacious than CBT (Whittal et al., 2010).”
    Quote in the paperSubstantial claim0 of 1 sources checked
    • cites Whittal et al., 2010 source
  • Probably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.

    Interpretationcitation

    Both EMDR and satiation therapy involve some exposure, which might be a critical ingredient.

    “Both EMDR (Nazari et al., 2011) and satiation therapy (Khodarahimi, 2009) involve some exposure, which might be a critical ingredient.”
    Quote in the paperNot a substantial claim0 of 2 sources checked
    • cites Nazari et al., 2011 source
    • cites Khodarahimi, 2009 source
  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Premisecitation

    Access to appropriate training and supervision is important for adoption and competent practice of empirically supported treatments.

    “Access to appropriate training and supervision is important for the adoption and competent practice of empirically supported treatments (Shafran et al., 2009).”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites Shafran et al., 2009 source
  • Probably not a substantial claim: may not pass S1 (asserted).

    Premisecitation

    It has been argued that behavioral procedures are most powerful means of producing cognitive change.

    “It has been argued that behavioral procedures are the most powerful means of producing cognitive change (Bandura, 1977).”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites Bandura, 1977 source
  • May combine two claims.

    Premisecitation

    Stress Management was less efficacious than ERP when combined with pill placebo, when added to ongoing medication treatment in partial responders, and when added to substance abuse treatment in comorbid patients.

    “Stress Management was less efficacious than ERP when combined with pill placebo in a study in Japan (Nakatani et al., 2005), and less efficacious than ERP when added to ongoing medication treatment in patients who had shown partial response (Simpson et al., 2008b), and when added to substance abuse treatment in a therapeutic community for patients with comorbid substance use disorders (Fals-Stewar”
    Quote in the paperSubstantial claim0 of 3 sources checked
    • cites Nakatani et al., 2005 source
    • cites Simpson et al., 2008b

      Couldn’t be matched to a paper in Crossref, so it can’t be checked.

    • cites Fals-Stewart & Schafer, 1992 source
  • May combine two claims.

    Premisecitation

    Symptom reduction was significantly greater among patients who received MI, with further reductions over subsequent 3-month follow-up.

    “Symptom reduction was significantly greater among patients who received MI, with further reductions in OCD symptoms over a subsequent 3-month follow-up.”
    Quote in the paperSubstantial claim0 of 1 sources checked
    • cites Meyer et al., 2010a

      Couldn’t be matched to a paper in Crossref, so it can’t be checked.

68 of 68
  • The paper relies on this without support.

    A dimensional understanding of OCD's symptomatic heterogeneity has important implications for treatment.

    “Nonetheless, a dimensional understanding of the symptomatic heterogeneity in OCD clearly has important implications for treatment.”
1 of 1

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • Systematic reviews and meta-analyses support that CBT programs are effective in reducing OCD symptoms, with effect sizes ranging from 0.8 to 1.24 from pre- to post-treatment.

    “Systematic reviews and meta-analyses support that CBT programs are effective in reducing OCD symptoms, with effect sizes ranging from 0.8 to 1.24 from pre to post treatment [10–15].”

    From Study protocol for a randomised controlled trial of internet-based cognitive-behavioural therapy for obsessive-compulsive disorder (2014) · cites this paper as [12]

    The Results (Cognitive Interventions; page unavailable) report that CBT was superior to wait-list controls in every relevant trial and conclude that it reduces OCD symptoms. The paper does not report the claimed pre-to-post effect-size range of 0.8 to 1.24; searches for those numbers and for pre-to-post effect sizes did not find it. (LLM, conf=0.86)

    Experimental — accuracy not yet measured
  • Both exposure-based and cognitive interventions may be comparably efficacious for BDD, arguably because these interventions may address the same maintaining factors (e.g., avoidance).

    “Like in OCD (Öst et al., 2015; Ponniah et al., 2013), both exposure-based and cognitive interventions may be comparably efficacious for BDD, arguably because these interventions may address the same maintaining factors (e.g., avoidance).”

Cites

Flagged first, then by citations

3 of the 160 references couldn’t be matched to a known paper.

Research works printed but not linked: 1

  1. Weissman, M. M. & Sanderson, W. C. (2001). Promises and problems in modern psychotherapy: the need for increased training in evidence-based treatments. In: Hager M., (Ed.), Modern psychiatry: challenges in educating health professionals to meet new needs (pp. 132–165). New York, NY: Josiah Macy, Jr. Foundation (for the Josiah Macy, Jr. Foundation conference, October 25–28, 2001).

Cited by

Sorted by citations

Authors
Ponniah, K., Magiati, I., & Hollon, S. D.
Affiliations
  • National University of Singapore (SG)
  • Vanderbilt University (US)
Corresponding author
Ponniah, Kathryn
Venue
Journal of Obsessive-Compulsive and Related Disorders
Publisher
Elsevier BV
Published
2013-04
Volume
2
Issue
2
Pages
207-218
ISSN
2211-3649 (ISSN-L)
OpenAlex
W1562552142
Cited by
79
References
160
Citations by year
2026: 2 · 2025: 5 · 2024: 5 · 2023: 4 · 2022: 4 · 2021: 5 · 2020: 7 · 2019: 6 · 2018: 8 · 2017: 11 · 2016: 6 · 2015: 5 · 2014: 9 · 2013: 2
FWCI
8.16
Type
journal article
Language
en
Open access
Locations
  • Journal of Obsessive-Compulsive and Related Disorders (publishedVersion)
  • PubMed (publishedVersion)
  • Europe PMC (PubMed Central) (acceptedVersion)
  • PubMed Central (acceptedVersion)
  • National University of Singapore (submittedVersion)
Funders
  • Josiah Macy Jr. Foundation
  • National University of Singapore
  • National Institute of Mental Health (K02MH001697)
Topics
  • Social Sciences › Psychology › Clinical Psychology › Obsessive-Compulsive Spectrum Disorders
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
  • Social Sciences › Psychology › Clinical Psychology › Psychoanalysis and Psychopathology Research
Keywords
obsessive-compulsive disorder, psychological intervention, exposure and response prevention, cognitive behavioral therapy, acceptance and commitment therapy, motivational interviewing, EMDR, stress management, psychodynamic psychotherapy, contamination obsessions, washing compulsions, treatment efficacy

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Claims read under definition version 3 (extract-v3) on 2026-09-28.

Classified by jev-1.13-20260917 (gold-guideline-v0.2) on 2026-09-28.

Cited sources are checked by gpt-6-sol.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review