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The kinase TAK1 can activate the NIK-IκB as well as the MAP kinase cascade in the IL-1 signalling pathway

Ninomiya-Tsuji, Jun, Kishimoto, Kazuya, Hiyama, Atsushi, Inoue, Jun-ichiro, Cao, Zhaodan, Matsumoto, Kunihiro·1999·Nature

DOI 10.1038/18465

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“…various stimuli, including cytokines as well as ligands of Toll-like-, B cell- and T cell receptors, and a key signaling component of NF-κB and MAPK signaling pathways that exerts cell type-specific functions (Ninomiya-Tsuji et al., 1999; Wang et al., 2001; Wan et al., 2006; Schuman et al., 2009).”
Background
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Activating; ‐catenin/Pax6 axis negatively regulates osteoclastogenesis by selectively inhibiting phosphorylation of p38/MAPK
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Authors: Ninomiya-Tsuji, J., Kishimoto, K., Hiyama, A., Inoue, J.-I., Cao, Z., & Matsumoto, K.
Venue: Nature
Publisher: Springer Science and Business Media LLC
Published: 1999-03
Volume: 398
Issue: 6724
Pages: 252-256
ISSN: 0028-0836 (ISSN-L)
1476-4687
DOI: 10.1038/18465
OpenAlex: W1575383081
Cited by: 1,182
References: 1
FWCI: 28.42
Type: journal article
Language: en
Open access: closed

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The kinase TAK1 can activate the NIK-IκB as well as the MAP kinase cascade in the IL-1 signalling pathway

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