Towards a molecular understanding of adaptive thermogenesis

Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1

Wu, Z., Puigserver, P., Andersson, U., Zhang, C., Adelmant, G., Mootha, V., Troy, A., Cinti, S., Lowell, B., Scarpulla, R. C., et al. (1999) · Cell · doi:10.1016/s0092-8674(00)80611-x · Cited by 4,139

A Cold-Inducible Coactivator of Nuclear Receptors Linked to Adaptive Thermogenesis

Puigserver, P., Wu, Z., Park, C. W., Graves, R., Wright, M., & Spiegelman, B. M. (1998) · Cell · doi:10.1016/s0092-8674(00)81410-5 · Cited by 3,864

Role of leptin in the neuroendocrine response to fasting

Ahima, R. S., Prabakaran, D., Mantzoros, C., Qu, D., Lowell, B., Maratos-Flier, E., & Flier, J. S. (1996) · Nature · doi:10.1038/382250a0 · Cited by 3,117

Cellular energy utilization and molecular origin of standard metabolic rate in mammals

Rolfe, D. F., & Brown, G. C. (1997) · Physiological Reviews · doi:10.1152/physrev.1997.77.3.731 · Cited by 2,021

Changes in Energy Expenditure Resulting from Altered Body Weight

Leibel, R. L., Rosenbaum, M., & Hirsch, J. (1995) · New England Journal of Medicine · doi:10.1056/nejm199503093321001 · Cited by 2,012

Uncoupling protein-2: a novel gene linked to obesity and hyperinsulinemia

Fleury, C., Neverova, M., Collins, S., Raimbault, S., Champigny, O., Lévi-Meyrueis, C., Bouillaud, F., Seldin, M. F., Surwit, R. S., Ricquier, D., et al. (1997) · Nature Genetics · doi:10.1038/ng0397-269 · Cited by 1,630

Thermogenic mechanisms in brown fat.

Nicholls, D. G., & Locke, R. M. (1984) · Physiological Reviews · doi:10.1152/physrev.1984.64.1.1 · Cited by 1,602

Role of calcium ions in regulation of mammalian intramitochondrial metabolism

McCormack, J. G., Halestrap, A. P., & Denton, R. M. (1990) · Physiological Reviews · doi:10.1152/physrev.1990.70.2.391 · Cited by 1,398

Mice lacking mitochondrial uncoupling protein are cold-sensitive but not obese

Enerbäck, S., Jacobsson, A., Simpson, E. M., Guerra, C., Yamashita, H., Harper, M.-E., & Kozak, L. P. (1997) · Nature · doi:10.1038/387090a0 · Cited by 1,379

The Response to Long-Term Overfeeding in Identical Twins

Bouchard, C., Tremblay, A., Després, J.-P., Nadeau, A., Lupien, P. J., Thériault, G., Dussault, J., Moorjani, S., Pinault, S., & Fournier, G. (1990) · New England Journal of Medicine · doi:10.1056/nejm199005243222101 · Cited by 1,278

Induction of thermogenic adipocytes: molecular targets and thermogenic small molecules

Song, N.-J., Chang, S., Li, D. Y., Villanueva, C. J., & Park, K. W. (2017) · Experimental & Molecular Medicine · doi:10.1038/emm.2017.70 · Cited by 81

Role of Sarco/Endoplasmic Reticulum Ca2+-ATPase in Thermogenesis

MEIS, L. D., Arruda, A. P., & de Carvalho, D. P. (2005) · Bioscience Reports · doi:10.1007/s10540-005-2884-7 · Cited by 79

Does body mass play a role in the regulation of food intake?

Speakman, J. R., Stubbs, R. J., & Mercer, J. G. (2002) · Proceedings of The Nutrition Society · doi:10.1079/pns2002194 · Cited by 79

A Mutant Thyroid Hormone Receptor α Antagonizes Peroxisome Proliferator-Activated Receptor α Signaling in Vivo and Impairs Fatty Acid Oxidation

Liu, Y., Heymann, R. S., Moatamed, F., Schultz, J. J., Sobel, D., & Brent, G. A. (2006) · Endocrinology · doi:10.1210/en.2006-0836 · Cited by 79

Single-cell photoacoustic thermometry

Gao, L. S., Wang, L., Li, C., Liu, Y., Ke, H., Zhang, C., & Wang, L. V. (2013) · Journal of Biomedical Optics · doi:10.1117/1.jbo.18.2.026003 · Cited by 79

Increased Energy Expenditure, Ucp1 Expression, and Resistance to Diet-induced Obesity in Mice Lacking Nuclear Factor-Erythroid-2-related Transcription Factor-2 (Nrf2)

Schneider, K., Valdez, J. L., Nguyen, J. M., Vawter, M. P., Galke, B. L., Kurtz, T. W., & Chan, J. Y. (2016) · Journal of Biological Chemistry · doi:10.1074/jbc.m115.673756 · Cited by 83

Nucleic Acid Based Fluorescent Nanothermometers

Ebrahimi, S., Akhlaghi, Y., Kompany‐Zareh, M., & Rinnan, Å. (2014) · ACS Nano · doi:10.1021/nn5036944 · Cited by 79

Bladder drug mirabegron exacerbates atherosclerosis through activation of brown fat-mediated lipolysis

Sui, W., Li, H., Yang, Y., Xu, J., Xue, F., Cheng, J., Dong, M., Zhang, M., Pan, H., Chen, Y., et al. (2019) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1901655116 · Cited by 81

Mitochondrial uncoupling protein 2 in the central nervous system: neuromodulator and neuroprotector

Horváth, T. L., Diano, S., & Barnstable, C. J. (2003) · Biochemical Pharmacology · doi:10.1016/s0006-2952(03)00143-6 · Cited by 81

Ultrasensitive ratiometric fluorescent pH and temperature probes constructed from dye-labeled thermoresponsive double hydrophilic block copolymers

Hu, J., Zhang, X.-Z., Wang, D., Hu, X., Liu, T., Zhang, G., & Liu, S. (2011) · Journal of Materials Chemistry · doi:10.1039/c1jm13575a · Cited by 78

Mitochondrial dysfunction in AIDS and its treatment

Gerschenson, M., & Brinkman, K. (2004) · Mitochondrion · doi:10.1016/j.mito.2004.07.025 · Cited by 78

Mitochondrial proton leak: a role for uncoupling proteins 2 and 3?

Porter, R. K. (2001) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/s0005-2728(00)00246-2 · Cited by 79

Exercise-Induced Adaptations to Adipose Tissue Thermogenesis

Vidal, P., & Stanford, K. I. (2020) · Frontiers in Endocrinology · doi:10.3389/fendo.2020.00270 · Cited by 84

Regulation of brown fat by AMP-activated protein kinase

van Dam, A. D., Kooijman, S., Schilperoort, M., Rensen, P. C. N., & Boon, M. R. (2015) · Trends in Molecular Medicine · doi:10.1016/j.molmed.2015.07.003 · Cited by 79

Regulation of thermogenesis by the central melanocortin system

Fan, W., Voss-Andreae, A., Cao, W.-H., & Morrison, S. F. (2005) · Peptides · doi:10.1016/j.peptides.2004.11.033 · Cited by 77

THE NEUROENDOCRINOLOGY OF CHILDHOOD OBESITY

Lustig, R. H. (2001) · Pediatric Clinics of North America · doi:10.1016/s0031-3955(05)70348-5 · Cited by 78

SF-1 in the ventral medial hypothalamic nucleus: A key regulator of homeostasis

Kim, K. W., Sohn, J.-W., Kohno, D., Xu, Y., Williams, K., & Elmquist, J. K. (2011) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2010.11.019 · Cited by 76

Mitophagy is required for brown adipose tissue mitochondrial homeostasis during cold challenge

Lu, Y., Fujioka, H., Joshi, D., Li, Q., Sangwung, P., Hsieh, P., Zhu, J., Torio, J., Sweet, D., Wang, L., et al. (2018) · Scientific Reports · doi:10.1038/s41598-018-26394-5 · Cited by 76

Cooperative role of the glucagon‐like peptide‐1 receptor and β3‐adrenergic‐mediated signalling on fat mass reduction through the downregulation of PKA / AKT / AMPK signalling in the adipose tissue and muscle of rats

Decara, J. M., Rivera, P., Arrabal, S., Vargas, A., Serrano, A., Pavón, F. J., Diéguez, C., Nogueiras, R., de Fonseca, F. R., & Suárez, J. (2017) · Acta Physiologica · doi:10.1111/apha.13008 · Cited by 77

Role of Leptin in Peroxisome Proliferator-Activated Receptor Gamma Coactivator-1 Expression1

Kakuma, T., Wang, Z.-W., Pan, W., Unger, R. H., & Zhou, Y.-T. (2000) · Endocrinology · doi:10.1210/endo.141.12.7804 · Cited by 76

Identification of a biochemical link between energy intake and energy expenditure

Obici, S., Wang, J., Chowdury, R., Feng, Z., Siddhanta, U., Morgan, K., & Rossetti, L. (2002) · Journal of Clinical Investigation · doi:10.1172/jci15258 · Cited by 76

Dual-Emissive Phosphorescent Polymer Probe for Accurate Temperature Sensing in Living Cells and Zebrafish Using Ratiometric and Phosphorescence Lifetime Imaging Microscopy

Zhang, H., Jiang, J., Gao, P., Yang, T., Zhang, K. Y., Chen, Z., Liu, S., Huang, W., & Zhao, Q. (2018) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.8b01565 · Cited by 75

Peripheral and hypothalamic leptin resistance with age-related obesity

Scarpace, P. J., & Tümer, N. (2001) · Physiology & Behavior · doi:10.1016/s0031-9384(01)00616-3 · Cited by 75

Skeletal muscle metabolism in physiology and in cancer disease

Giordano, A. M., Calvani, M., Petillo, O., Carteni', M., Melone, M. A. B., & Peluso, G. (2003) · Journal of Cellular Biochemistry · doi:10.1002/jcb.10601 · Cited by 76

Macrophage IRX3 promotes diet-induced obesity and metabolic inflammation

Yao, J., Wu, D., Zhang, C., Yan, T., Zhao, Y., Shen, H., Xue, K., Huang, X., Wang, Z., & Qiu, Y. (2021) · Nature Immunology · doi:10.1038/s41590-021-01023-y · Cited by 75

Control of Cardiac-specific Transcription by p300 through Myocyte Enhancer Factor-2D

Slepak, T. I., Webster, K. A., Zang, J., Prentice, H. M., O'Dowd, A., Hicks, M. N., & Bishopric, N. H. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m004625200 · Cited by 74

Mfsd2a encodes a novel major facilitator superfamily domain-containing protein highly induced in brown adipose tissue during fasting and adaptive thermogenesis

Angers, M., Uldry, M., Kong, D., Gimble, J. M., & Jetten, A. M. (2008) · Biochemical Journal · doi:10.1042/bj20080165 · Cited by 75

Supraclavicular skin temperature and BAT activity in lean healthy adults

van der Lans, A. A. J. J., Vosselman, M. J., Hanssen, M. J. W., Brans, B. T., & Lichtenbelt, W. D. V. M. (2015) · The Journal of Physiological Sciences · doi:10.1007/s12576-015-0398-z · Cited by 78

Phytochemicals as potential candidates to combat obesity via adipose non-shivering thermogenesis

Li, H., Qi, J., & Li, L. (2019) · Pharmacological Research · doi:10.1016/j.phrs.2019.104393 · Cited by 76

Focus on FKBP51: A molecular link between stress and metabolic disorders

Häusl, A. S., Balsevich, G., Gassen, N. C., & Schmidt, M. V. (2019) · Molecular Metabolism · doi:10.1016/j.molmet.2019.09.003 · Cited by 73

Natural Selection and Adaptive Evolution of Leptin in the Ochotona Family Driven by the Cold Environmental Stress

Yang, J., Wang, Z. L., Zhao, X. Q., Wang, D. P., Qi, D. L., Xu, B. H., Ren, Y., & Tian, H. F. (2008) · PLoS ONE · doi:10.1371/journal.pone.0001472 · Cited by 75

THE NEUROENDOCRINOLOGY OF OBESITY

Lustig, R. H. (2001) · Endocrinology and Metabolism Clinics of North America · doi:10.1016/s0889-8529(05)70211-5 · Cited by 73

Fluorescent water-soluble responsive polymers site-specifically labeled with FRET dyes possessing pH- and thermo-modulated multicolor fluorescence emissions as dual ratiometric probes

Wan, X., & Liu, S. (2011) · Journal of Materials Chemistry · doi:10.1039/c1jm10332f · Cited by 73

Hypothalamic AMPK as a Regulator of Energy Homeostasis

Huynh, M. K. Q., Kinyua, A. W., Yang, D. J., & Kim, K. W. (2016) · Neural Plasticity · doi:10.1155/2016/2754078 · Cited by 78

Ablations of Ghrelin and Ghrelin Receptor Exhibit Differential Metabolic Phenotypes and Thermogenic Capacity during Aging

Ma, X., Lin, L., Qin, G., Lu, X., Fiorotto, M. L., Dixit, V. D., & Sun, Y. (2011) · PLoS ONE · doi:10.1371/journal.pone.0016391 · Cited by 75

Role of RIP140 in metabolic tissues: Connections to disease

White, R., Morganstein, D. L., Christian, M., Seth, A., Herzog, B., & Parker, M. G. (2007) · FEBS Letters · doi:10.1016/j.febslet.2007.11.017 · Cited by 71

Integrative Approaches for Studying Mitochondrial and Nuclear Genome Co-evolution in Oxidative Phosphorylation

Sunnucks, P., Morales, H. E., Lamb, A. M., Pavlova, A., & Greening, C. (2017) · Frontiers in Genetics · doi:10.3389/fgene.2017.00025 · Cited by 74

Nature's fat-burning machine: brown adipose tissue in a hibernating mammal

Ballinger, M. A., & Andrews, M. T. (2018) · Journal of Experimental Biology · doi:10.1242/jeb.162586 · Cited by 72

Thyroid Hormone Mediated Modulation of Energy Expenditure

Vaitkus, J. A., Farrar, J. S., & Celi, F. S. (2015) · International Journal of Molecular Sciences · doi:10.3390/ijms160716158 · Cited by 71

Vitamin A Intake Is Inversely Related with Adiposity in Healthy Young Adults

Zulet, M. Á., Puchau, B., Hermsdorff, H. H. M., Navarro, C., & Martínez, J. A. (2008) · Journal of Nutritional Science and Vitaminology · doi:10.3177/jnsv.54.347 · Cited by 71

Mice lacking δ‐opioid receptors resist the development of diet‐induced obesity

Czyzyk, T. A., Romero, A., Pintar, J. E., McKinzie, J. H., Tschöp, M. H., Statnick, M. A., & Nogueiras, R. (2012) · The FASEB Journal · doi:10.1096/fj.12-208041 · Cited by 73

Fundamental links between genes and elements: evolutionary implications of ecological stoichiometry

Jeyasingh, P. D., & Weider, L. J. (2007) · Molecular Ecology · doi:10.1111/j.1365-294x.2007.03558.x · Cited by 71

Characterization of weight loss and weight regain mechanisms after Roux-en-Y gastric bypass in rats

Guijarro, A. I., Suzuki, S., Chen, C., Kirchner, H., Middleton, F. A., Nadtochiy, S. M., Brookes, P. S., Niijima, A., Inui, A., & Meguid, M. M. (2007) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00171.2007 · Cited by 71

TRPV4 deficiency increases skeletal muscle metabolic capacity and resistance against diet-induced obesity

Kusudo, T., Wang, Z., Mizuno, A., Suzuki, M., & Yamashita, H. (2011) · Journal of Applied Physiology · doi:10.1152/japplphysiol.01070.2011 · Cited by 70

A bioluminescent probe for longitudinal monitoring of mitochondrial membrane potential

Bazhin, A. A., Sinisi, R., Marchi, U. D., Hermant, A., Sambiagio, N., Maric, T., Budin, G., & Goun, E. A. (2020) · Nature Chemical Biology · doi:10.1038/s41589-020-0602-1 · Cited by 71

Mineralocorticoid receptor in adipocytes and macrophages: A promising target to fight metabolic syndrome

Marzolla, V., Armani, A., Feraco, A., Martino, M. U. D., Fabbri, A., Rosano, G. M. C., & Caprio, M. (2014) · Steroids · doi:10.1016/j.steroids.2014.05.001 · Cited by 75

Brain Circuits Regulating Energy Homeostasis

Horváth, T. L., Diano, S., & Tschöp, M. H. (2004) · The Neuroscientist · doi:10.1177/1073858403262151 · Cited by 71

Adaptive thermogenesis in hummingbirds

Bicudo, J. E. P. W., Bianco, A. C., & Vianna, C. R. (2002) · Journal of Experimental Biology · doi:10.1242/jeb.205.15.2267 · Cited by 68

Capsaicin and Related Food Ingredients Reducing Body Fat Through the Activation of TRP and Brown Fat Thermogenesis

Saito, M. (2015) · Advances in food and nutrition research · doi:10.1016/bs.afnr.2015.07.002 · Cited by 71

Hybrid micro-/nanogels for optical sensing and intracellular imaging

Wu, W., & Zhou, S. (2010) · Nano Reviews · doi:10.3402/nano.v1i0.5730 · Cited by 69

Analysis of energy expenditure at different ambient temperatures in mice lacking DGAT1

Chen, H. C., Ladha, Z., Smith, S. J., & Farese, R. V. (2003) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00248.2002 · Cited by 69

Identification of a biochemical link between energy intake and energy expenditure

Obici, S., Wang, J., Chowdury, R., Feng, Z., Siddhanta, U., Morgan, K., & Rossetti, L. (2002) · Journal of Clinical Investigation · doi:10.1172/jci0215258 · Cited by 69

Emodin Improves Glucose and Lipid Metabolism Disorders in Obese Mice via Activating Brown Adipose Tissue and Inducing Browning of White Adipose Tissue

Cheng, L., Zhang, S., Shang, F., Ning, Y., Huang, Z., He, R., Sun, J., & Dong, S. (2021) · Frontiers in Endocrinology · doi:10.3389/fendo.2021.618037 · Cited by 68

TNF‐α inhibits UCP‐1 expression in brown adipocytes via ERKs

Valladares, A., Roncero, C., Benito, M., & Porrás, A. (2001) · FEBS Letters · doi:10.1016/s0014-5793(01)02264-5 · Cited by 68

Tranilast, an antifibrogenic agent, ameliorates a dietary rat model of nonalcoholic steatohepatitis†

Uno, M., Kurita, S., Misu, H., Ando, H., Ota, T., Nagata, N., Kita, Y., Nabemoto, S., Akahori, H., Zen, Y., et al. (2008) · Hepatology · doi:10.1002/hep.22338 · Cited by 68

Obesity and its potential mechanistic basis

Prentice, A. M. (2001) · British Medical Bulletin · doi:10.1093/bmb/60.1.51 · Cited by 67

Lipolysis and thermogenesis in adipose tissues as new potential mechanisms for metabolic benefits of dietary fiber

Han, S.-F., Jiao, J., Zhang, W., Xu, J., Zhang, W., Chun-ling, F., & Qin, L. (2016) · Nutrition · doi:10.1016/j.nut.2016.05.006 · Cited by 69

Immune Modulation of Brown(ing) Adipose Tissue in Obesity

van den Berg, S. M., van Dam, A. D., Rensen, P. C. N., de Winther, M. P. J., & Lutgens, E. (2016) · Endocrine Reviews · doi:10.1210/er.2016-1066 · Cited by 69

Leptin-Induced Leptin Resistance Reveals Separate Roles for the Anorexic and Thermogenic Responses in Weight Maintenance

Scarpace, P. J., Matheny, M. E., Zhang, Y., Shek, E. W., Prima, V., Zolotukhin, S., & Tümer, N. (2002) · Endocrinology · doi:10.1210/endo.143.8.8966 · Cited by 67

Dieckol, a major phlorotannin in Ecklonia cava, suppresses lipid accumulation in the adipocytes of high‐fat diet‐fed zebrafish and mice: Inhibition of early adipogenesis via cell‐cycle arrest and AMPKα activation

Choi, H., Jeon, H., Lee, O., & Lee, B. (2015) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.201500021 · Cited by 67

Biochemical adaptations of mammalian hibernation: exploring squirrels as a perspective model for naturally induced reversible insulin resistance

Wu, C., Biggar, K. K., & Storey, K. B. (2013) · Brazilian Journal of Medical and Biological Research · doi:10.1590/1414-431x20122388 · Cited by 69

Ratiometric Fluorescent Polymeric Thermometer for Thermogenesis Investigation in Living Cells

Qiao, J., Hwang, Y., Chen, C.-F., Qi, L., Dong, P., Mu, X., & Kim, D. (2015) · Analytical Chemistry · doi:10.1021/acs.analchem.5b02791 · Cited by 67

Evidence for Nr4a1 as a cold-induced effector of brown fat thermogenesis

Kanzleiter, T., Schneider, T., Walter, I. J., Bolze, F., Eickhorst, C., Heldmaier, G., Klaus, S., & Klingenspor, M. (2005) · Physiological Genomics · doi:10.1152/physiolgenomics.00204.2005 · Cited by 66

Cyanidin-3-glucoside attenuates high-fat and high-fructose diet-induced obesity by promoting the thermogenic capacity of brown adipose tissue

You, Y., Han, X., Guo, J., Guo, Y., Yin, M., Liu, G., Huang, W., & Zhan, J. (2018) · Journal of Functional Foods · doi:10.1016/j.jff.2017.12.025 · Cited by 65

Leucine deprivation stimulates fat loss via increasing CRH expression in the hypothalamus and activating the sympathetic nervous system

Cheng, Y., Zhang, Q., Meng, Q., Xia, T., Huang, Z., Wang, C., Liu, B., Chen, S., Xiao, F., Du, Y., et al. (2011) · Molecular Endocrinology · doi:10.1210/me.2011-0028 · Cited by 65

Intracellular glycolysis in brown adipose tissue is essential for optogenetically induced nonshivering thermogenesis in mice

Jeong, J. H., Chang, J. S., & Jo, Y. (2018) · Scientific Reports · doi:10.1038/s41598-018-25265-3 · Cited by 67

A twisted tale: measuring viscosity and temperature of microenvironments using molecular rotors

Vyšniauskas, A., & Kuimova, M. K. (2018) · International Reviews in Physical Chemistry · doi:10.1080/0144235x.2018.1510461 · Cited by 65

Negative regulation of UCP2 by TGFβ signaling characterizes low and intermediate-grade primary breast cancer

Sayeed, A., Meng, Z., Luciani, G., Chen, L., Bennington, J. L., & Dairkee, S. H. (2010) · Cell Death and Disease · doi:10.1038/cddis.2010.30 · Cited by 68

Anti-obesity Effect of Pinellia ternata Extract in Zucker Rats

Kim, Y.-J., Shin, Y., Ha, Y.-W., Lee, S., Oh, J., & Kim, Y. S. (2006) · Biological and Pharmaceutical Bulletin · doi:10.1248/bpb.29.1278 · Cited by 65

Endocannabinoid regulation in white and brown adipose tissue following thermogenic activation

Krott, L. M., Piscitelli, F., Heine, M., Borrino, S., Scheja, L., Silvestri, C., Heeren, J., & Marzo, V. D. (2016) · Journal of Lipid Research · doi:10.1194/jlr.m065227 · Cited by 71

Activation and recruitment of brown adipose tissue by cold exposure and food ingredients in humans

Saito, M., Yoneshiro, T., & Matsushita, M. (2016) · Best Practice & Research Clinical Endocrinology & Metabolism · doi:10.1016/j.beem.2016.08.003 · Cited by 67

Effects of nicotine on homeostatic and hedonic components of food intake

Stojakovic, A., Espinosa, E. V. P., Farhad, O. T., & Lutfy, K. (2017) · Journal of Endocrinology · doi:10.1530/joe-17-0166 · Cited by 65

Leptin Expression in Hypothalamic PVN Reverses Dietary Obesity and Hyperinsulinemia but Stimulates Ghrelin*

Bagnasco, M., Dube, M. G., Katz, A. A., Kalra, P. S., & Kalra, S. P. (2003) · Obesity Research · doi:10.1038/oby.2003.196 · Cited by 65

Glucose homeostasis in the newborn

Hume, R., Burchell, A. N., Williams, F. L. R., & Koh, D. K. M. (2004) · Early Human Development · doi:10.1016/j.earlhumdev.2004.10.005 · Cited by 65

The sympathetic nervous system is controlled by transient receptor potential vanilloid 1 in the regulation of body temperature

Alawi, K. M., Aubdool, A. A., Liang, L., Wilde, E., Vepa, A., Psefteli, M., Brain, S. D., & Keeble, J. E. (2015) · The FASEB Journal · doi:10.1096/fj.15-272526 · Cited by 64

A Critical Review on the Role of Food and Nutrition in the Energy Balance

Bo, S., Fadda, M., Fedele, D., Pellegrini, M., Ghigo, E., & Pellegrini, N. (2020) · Nutrients · doi:10.3390/nu12041161 · Cited by 72

The Role of Lipids, Lipid Metabolism and Ectopic Lipid Accumulation in Axon Growth, Regeneration and Repair after CNS Injury and Disease

Roy, D., & Tedeschi, A. (2021) · Cells · doi:10.3390/cells10051078 · Cited by 70

Leptin-mediated changes in hepatic mitochondrial metabolism, structure, and protein levels

Singh, A., Wirtz, M., Parker, N., Hogan, M., Strahler, J. R., Michailidis, G. C., Schmidt, S. F., Vidal‐Puig, A., Diano, S., Andrews, P., et al. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0903723106 · Cited by 68

Ursolic acid and mechanisms of actions on adipose and muscle tissue: a systematic review

Katashima, C. K., Silva, V. R. R., Gomes, T. L. N., Pichard, C., & Pimentel, G. D. (2017) · Obesity Reviews · doi:10.1111/obr.12523 · Cited by 65

Climate‐driven mitochondrial selection: A test in Australian songbirds

Lamb, A. M., Gan, H. M., Greening, C., Joseph, L., Lee, Y. P., Morán‐Ordóñez, A., Sunnucks, P., & Pavlova, A. (2018) · Molecular Ecology · doi:10.1111/mec.14488 · Cited by 64

Plasticity in metabolic allometry: the role of dietary stoichiometry

Jeyasingh, P. D. (2007) · Ecology Letters · doi:10.1111/j.1461-0248.2007.01023.x · Cited by 63

Long-Term Suppression of Weight Gain, Adiposity, and Serum Insulin by Central Leptin Gene Therapy in Prepubertal Rats: Effects on Serum Ghrelin and Appetite-Regulating Genes

Beretta, E., Dube, M. G., Kalra, P. S., & Kalra, S. P. (2002) · Pediatric Research · doi:10.1203/00006450-200208000-00010 · Cited by 63

Role of the Sarcoplasmic Reticulum Ca2+-ATPase on Heat Production and Thermogenesis

MEIS, L. D. (2001) · Bioscience Reports · doi:10.1023/a:1013640006611 · Cited by 63

Topiramate Treatment Improves Hypothalamic Insulin and Leptin Signaling and Action and Reduces Obesity in Mice

Caricilli, A. M., Penteado, É., de Abreu, L. L., Quaresma, P. G. F., Santos, A. C., Guadagnini, D., Razolli, D. S., Mittestainer, F. C., Carvalheira, J. B. C., Velloso, L. A., et al. (2012) · Endocrinology · doi:10.1210/en.2012-1272 · Cited by 63

Reversal of diet-induced obesity and insulin resistance by inducible genetic ablation of GRK2

Vila‐Bedmar, R., Cruces‐Sande, M., Lucas, E., Willemen, H. L. D. M., Heijnen, C. J., Kavelaars, A., Mayor, F., & Murga, C. (2015) · Science Signaling · doi:10.1126/scisignal.aaa4374 · Cited by 62

Living cell intracellular temperature imaging with biocompatible dye-conjugated carbon dots

Wei, L., Ma, Y., Shi, X., Wang, Y., Su, X., Yu, C., Xiang, S., Xiao, L., & Chen, B. (2017) · Journal of Materials Chemistry B · doi:10.1039/c7tb00309a · Cited by 63

Tyrosine-dependent and -independent actions of leptin receptor in control of energy balance and glucose homeostasis

Jiang, L., You, J., Yu, X., Gonzalez, L., Yu, Y., Wang, Q. A., Yang, G., Li, W., Cai, L., & Liu, Y. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0804589105 · Cited by 61

A link between hepatic glucose production and peripheral energy metabolism via hepatokines

Abdul-Wahed, A., Gautier‐Stein, A., Casteras, S., Soty, M., Roussel, D., Romestaing, C., Guillou, H., Tourette, J.-A., Plèche, N., Zitoun, C., et al. (2014) · Molecular Metabolism · doi:10.1016/j.molmet.2014.05.005 · Cited by 75

Type 2 Iodothyronine Deiodinase Levels Are Higher in Slow-Twitch than Fast-Twitch Mouse Skeletal Muscle and Are Increased in Hypothyroidism

Marsili, A., Ramadan, W., Harney, J. W., Mulcahey, M. A., Castroneves, L. A., Goemann, I. M., Wajner, S. M., Huang, S. A., Zavacki, A. M., Maia, A. L., et al. (2010) · Endocrinology · doi:10.1210/en.2010-0631 · Cited by 65

Dietary fat interacts with QTLs controlling induction ofPgc-1α andUcp1during conversion of white to brown fat

Coulter, A. A., Bearden, C. M., Liu, X., Koza, R. A., & Kozak, L. P. (2003) · Physiological Genomics · doi:10.1152/physiolgenomics.00057.2003 · Cited by 62

Roles of Norepinephrine, Free Fatty Acids, Thyroid Status, and Skeletal Muscle Uncoupling Protein 3 Expression in Sympathomimetic-Induced Thermogenesis

Sprague, J. E., Yang, X., Sommers, J., Gilman, T. L., & Mills, E. (2006) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.106.107755 · Cited by 63

The retinoblastoma gene is involved in multiple aspects of stem cell biology

Galderisi, U., Cipollaro, M., & Giordano, A. (2006) · Oncogene · doi:10.1038/sj.onc.1209736 · Cited by 62

Novel Highly Selective and Reversible Chemosensors Based on Dual-Ratiometric Fluorescent Electrospun Nanofibers with pH- and Fe3+-Modulated Multicolor Fluorescence Emission

Chen, B., Kuo, C., Huang, Y., Lu, S.-T., Liang, F., & Jiang, D. (2015) · ACS Applied Materials & Interfaces · doi:10.1021/am508029x · Cited by 61

A combination of exercise and capsinoid supplementation additively suppresses diet-induced obesity by increasing energy expenditure in mice

Ohyama, K., Nogusa, Y., Suzuki, K., Shinoda, K., Kajimura, S., & Bannai, M. (2014) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00354.2014 · Cited by 65

Impaired thermoregulation and beneficial effects of thermoneutrality in the 3×Tg-AD model of Alzheimer's disease

Vandal, M., White, P. J., Tournissac, M., Tremblay, C., St‐Amour, I., Drouin‐Ouellet, J., Bousquet, M., Traversy, M.-T., Planel, E., Marette, A., et al. (2016) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2016.03.024 · Cited by 64

Thyroid hormones and browning of adipose tissue

Weiner, J., Hankir, M. K., Heiker, J. T., Fenske, W. K., & Krause, K. (2017) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2017.01.011 · Cited by 64

Nanostructured La2O3: Yb3+/Er3+: Temperature sensing, optical heating and bio-imaging application

Sun, Z. H., Liu, G., Fu, Z., Sheng, T., Wei, Y., & Wu, Z. (2017) · Materials Research Bulletin · doi:10.1016/j.materresbull.2017.04.005 · Cited by 61

Caulis Spatholobi Ameliorates Obesity through Activating Brown Adipose Tissue and Modulating the Composition of Gut Microbiota

Zhang, C., Liu, J., He, X., Sheng, Y., Cui, Y., Li, H., Xu, J., Xu, W., & Huang, K. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20205150 · Cited by 62

CIDE-A, a novel link between brown adipose tissue and obesity

Lin, S., & Li, P. (2004) · Trends in Molecular Medicine · doi:10.1016/j.molmed.2004.07.005 · Cited by 61

Expression patterns of the organic cation/carnitine transporter family in adult murine brain

Lamhonwah, A., Hawkins, C. E., Tam, C., Wong, J., Mai, L., & Tein, I. (2007) · Brain and Development · doi:10.1016/j.braindev.2007.05.005 · Cited by 61

Mitochondrial thermogenesis and obesity

Gambert, S., & Ricquier, D. (2007) · Current Opinion in Clinical Nutrition & Metabolic Care · doi:10.1097/mco.0b013e3282f0b69d · Cited by 33

Thermogenesis and the Metabolic Syndrome

Bonet, M. L., Picó, C., & Palou, A. (2005) · Elsevier eBooks · doi:10.1016/b978-84-8174-892-5.50017-6 · Cited by 2

β-Adrenergic Receptors, Diet-induced Thermogenesis, and Obesity

Lowell, B. B., & Bachman, E. S. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.r300011200 · Cited by 174

The role of thermogenesis in the regulation of energy balance

Richard, D. (1989) · Canadian Journal of Physiology and Pharmacology · doi:10.1139/y89-059

Recent advances in adaptive thermogenesis: potential implications for the treatment of obesity

Wijers, S. L. J., Saris, W. H. M., & Lichtenbelt, W. D. V. M. (2009) · Obesity Reviews · doi:10.1111/j.1467-789x.2008.00538.x · Cited by 119