Naturally secreted oligomers of amyloid β protein potently inhibit hippocampal long-term potentiation in vivo
Walsh, Dominic M., Klyubin, Igor, Fadeeva, Julia V., Cullen, William K., Anwyl, Roger, Wolfe, Michael S., Rowan, Michael J., Selkoe, Dennis J.·2002·Nature
DOI 10.1038/416535a
Cited by (1,067)
Items 501–600 of 1,067
- Microglial activation facilitates Aβ plaque removal following intracranial anti-Aβ antibody administrationWilcock, Donna M, Munireddy, Sanjay K, Rosenthal, Arnon, Ugen, Kenneth E, Gordon, Marcia N, Morgan, Dave · 2004 · Neurobiology of Disease
- Drusen deposits associated with aging and age-related macular degeneration contain nonfibrillar amyloid oligomersLuibl, V. · 2006 · Journal of Clinical Investigation
- Neurotoxic protein oligomers — what you see is not always what you getBitan, Gal, Fradinger, Erica A, Spring, Sean M, Teplow, David B · 2005 · Amyloid
- Emerging roles of pathogens in Alzheimer diseaseJudith Miklossy · 2011 · Expert Reviews in Molecular Medicine
- Amyloid-β and Tau at the Crossroads of Alzheimer’s DiseaseGilbert Gallardo, David M. Holtzman · 2019 · Advances in experimental medicine and biology
- Kinetic fingerprints differentiate the mechanisms of action of anti-Aβ antibodiesSara Snogerup Linse, Tom Scheidt, Katja Bernfur, Michele Vendruscolo, Christopher Martin Dobson, Samuel I. A. Cohen, Eimantas Šileikis, Martin Lundqvist, Fang Qian, Tiernan T. O’Malley et al. · 2020 · Nature Structural & Molecular Biology
- Intranasal deferoxamine reverses iron-induced memory deficits and inhibits amyloidogenic APP processing in a transgenic mouse model of Alzheimer's diseaseChuang Guo, Tao Wang, Wei Hui Zheng, Zhongyan Shan, Weiping Teng, Zhan‐You Wang · 2012 · Neurobiology of Aging
- Metabotropic NMDA receptor function is required for β-amyloid–induced synaptic depressionHelmut W. H. G. Kessels, Sadegh Nabavi, Roberto Malinow · 2013 · Proceedings of the National Academy of Sciences
- Distinct Effects of Zn2+, Cu2+, Fe3+, and Al3+ on Amyloid-β Stability, Oligomerization, and AggregationWei-Ting Chen, Yi‐Hung Liao, Hui-Ming Yu, Irene Han-Juo Cheng, Yun‐Ru Chen · 2011 · Journal of Biological Chemistry
- β-Amyloid impairs axonal BDNF retrograde traffickingWayne W. Poon, Mathew M. Blurton-Jones, Christina H. Tu, Leila M. Feinberg, Meredith A. Chabrier, Joe W. Harris, Noo Li Jeon, Carl W. Cotman · 2009 · Neurobiology of Aging
- Substoichiometric Levels of Cu2+ Ions Accelerate the Kinetics of Fiber Formation and Promote Cell Toxicity of Amyloid-β from Alzheimer DiseaseSarell, Claire J., Wilkinson, Shane R., Viles, John H. · 2010 · Journal of Biological Chemistry
- Detection of Misfolded Aβ Oligomers for Sensitive Biochemical Diagnosis of Alzheimer’s DiseaseNatalia Salvadores, Mohammad Shahnawaz, Elio Angelo Scarpini, Fabrizio Tagliavini, Claudio A. Soto · 2014 · Cell Reports
- Soluble Amyloid β-Oligomers Affect Dielectric Membrane Properties by Bilayer Insertion and Domain Formation: Implications for Cell ToxicityGintaras Valinčius, Frank Heinrich, Rima Budvytytė, David J. Vanderah, Duncan J. McGillivray, Yuri Sokolov, James E. Hall, Mathias Lösche · 2008 · Biophysical Journal
- Research update: Alpha7 nicotinic acetylcholine receptor mechanisms in Alzheimer's diseaseH. Rheinallt Parri, Caterina M. Hernandez, Kelly T. Dineley · 2011 · Biochemical Pharmacology
- Adverse Stress, Hippocampal Networks, and Alzheimer’s DiseaseSarah M. Rothman, Mark P. Mattson · 2009 · NeuroMolecular Medicine
- The β-amyloid protein of Alzheimer's disease increases neuronal CRMP-2 phosphorylation by a Rho-GTP mechanismPetratos, Steven, Li, Qiao-Xin, George, Amee J., Hou, Xu, Kerr, Megan L., Unabia, Sharon E., Hatzinisiriou, Irene, Maksel, Danuta, Aguilar, Marie-Isabel, Small, David H. · 2008 · Brain
- Protein aggregation in disease: a role for folding intermediates forming specific multimeric interactionsArthur L. Horwich · 2002 · Journal of Clinical Investigation
- Metabolite-initiated protein misfolding may trigger Alzheimer's diseaseQinghai Zhang, Evan T. Powers, Jorge J. Nieva, Mary E. Huff, Maria A. Dendle, Jan Bieschke, Charles G. Glabe, Albert Eschenmoser, Paul Wentworth, Richard Alan Lerner et al. · 2004 · Proceedings of the National Academy of Sciences
- Nucleation-Dependent Polymerization Is an Essential Component of Amyloid-Mediated Neuronal Cell DeathWogulis, Mark, Wright, Sarah, Cunningham, Damian, Chilcote, Tamie, Powell, Kyle, Rydel, Russell E. · 2005 · The Journal of Neuroscience
- A label-free electrical impedimetric biosensor for the specific detection of Alzheimer's amyloid-beta oligomersJo V. Rushworth, Asif Ahmed, Heledd Jarosz-Griffiths, Niall M. Pollock, Nigel M. Hooper, Paul A. Millner · 2013 · Biosensors and Bioelectronics
- Mitochondrial Dysfunction: The First Domino in Brain Aging and Alzheimer's Disease?Kristina Leuner, Susanne Hauptmann, Reham Mahmoud Abdel-Kader, Isabel Scherping, Uta Keil, Joanna Benigna Strosznajder, Anne Eckert, Walter E. Müller · 2007 · Antioxidants and Redox Signaling
- Targeting the neurotoxic species in Alzheimer's disease: inhibitors of Aβ oligomerizationFernanda G. De Felice, Marcelo N. N. Vieira, Leonardo Martins Saraiva, José Daniel Figueroa‐Villar, José Garcia-Abreu, Roy Liu, Lei Chang, W L Klein, Sergio Teixeira Ferreira · 2004 · The FASEB Journal
- Synthesis of a library of oligothiophenes and their utilization as fluorescent ligands for spectral assignment of protein aggregatesT. Klingstedt, A. Åslund, Rozalyn Simon, Leif B. G. Johansson, J. Mason, Sofie Nyström, P. Hammarström, K. P. Nilsson · 2011 · Organic and biomolecular chemistry
- Neurotrophins, synaptic plasticity and dementiaOttavio Arancio, Moses V. Chao · 2007 · Current Opinion in Neurobiology
- CSF Biomarkers for Alzheimer's Disease DiagnosisAnoop Arunagiri, Pradeep Kumar Singh, Reeba Susan Jacob, Samir Kumar Maji · 2010 · International Journal of Alzheimer s Disease
- β-Amyloid-Mediated Inhibition of NMDA Receptor-Dependent Long-Term Potentiation Induction Involves Activation of Microglia and Stimulation of Inducible Nitric Oxide Synthase and SuperoxideQinwen Wang, Michael J. Rowan, Roger Anwyl · 2004 · Journal of Neuroscience
- Alzheimer’s Disease, Oligomers, and InflammationGianluigi Forloni, Claudia Balducci · 2018 · Journal of Alzheimer s Disease
- Molecular Dynamics Simulation of Amyloid β Dimer FormationBrigita Urbanc, Luis Cruz, Feng Ding, Deanne W. Sammond, Sagar D. Khare, Sergey V. Buldyrev, Eugene Stanley, Nikolay V. Dokholyan · 2004 · Biophysical Journal
- Intranasal H102 Peptide-Loaded Liposomes for Brain Delivery to Treat Alzheimer’s DiseaseXiaoyao Zheng, Xiayan Shao, Chi Zhang, Yuanzhen Tan, Qingfeng Liu, Wan Xu, Qizhi Zhang, Shumei Xu, Xinguo Jiang · 2015 · Pharmaceutical Research
- β-Amyloid Is Different in Normal Aging and in Alzheimer DiseaseAlessandra Piccini, Claudio Russo, Alessandra Gliozzi, Annalisa Relini, Antonella Vitali, Roberta Borghi, Luca Giliberto, Andrea Armirotti, Cristina D’Arrigo, Angela Bachi et al. · 2005 · Journal of Biological Chemistry
- The duality of amyloid-β: its role in normal and Alzheimer’s disease statesAli Azargoonjahromi · 2024 · Molecular Brain
- Generic hydrophobic residues are sufficient to promote aggregation of the Alzheimer's Aβ42 peptideWoojin Kim, Michael H. Hecht · 2006 · Proceedings of the National Academy of Sciences
- Structure and functions of the human amyloid precursor protein: The whole is more than the sum of its partsMatthias Gralle, Sergio Teixeira Ferreira · 2007 · Progress in Neurobiology
- Ferulic Acid Is a Nutraceutical β-Secretase Modulator That Improves Behavioral Impairment and Alzheimer-like Pathology in Transgenic MiceTakashi Mori, Naoki Koyama, Marie‐Victoire Guillot‐Sestier, Jun Tan, Terrence Town · 2013 · PLoS ONE
- Deferoxamine inhibits iron induced hippocampal tau phosphorylation in the Alzheimer transgenic mouse brainChuang Guo, Pu Wang, Manli Zhong, Tao Wang, Xueshi Huang, Jiayi Li, Zhan‐You Wang · 2012 · Neurochemistry International
- A three-step model for the synaptic recruitment of AMPA receptorsOpazo, Patricio, Choquet, Daniel · 2011 · Molecular and Cellular Neuroscience
- Alzheimer's Disease: Redox Dysregulation As a Common Denominator for Diverse Pathogenic MechanismsRommy von Bernhardi M., Jaime L. Eugenín · 2011 · Antioxidants and Redox Signaling
- Targeting the proper amyloid-beta neuronal toxins: a path forward for Alzheimer’s disease immunotherapeuticsGoure, William F, Krafft, Grant A, Jerecic, Jasna, Hefti, Franz · 2014 · Alzheimer's Research & Therapy
- Neurotoxic, Redox-competent Alzheimer's β-Amyloid Is Released from Lipid Membrane by Methionine OxidationKevin Jeffrey Barnham, Giuseppe D. Ciccotosto, Anna K. Tickler, Feda E. A. Ali, Danielle G. Smith, Nicholas A. Williamson, Yuen-Han Lam, Darryl Carrington, Deborah J. Tew, Gulcan Kocak et al. · 2003 · Journal of Biological Chemistry
- Chemical and Biological Approaches for Adapting Proteostasis to Ameliorate Protein Misfolding and Aggregation Diseases-Progress and PrognosisSusan Lindquist, Jeffery W. Kelly · 2011 · Cold Spring Harbor Perspectives in Biology
- Methylene Blue Inhibits Amyloid Aβ Oligomerization by Promoting FibrillizationNecula, Mihaela, Breydo, Leonid, Milton, Saskia, Kayed, Rakez, van der Veer, Wytze E., Tone, Paul, Glabe, Charles G. · 2007 · Biochemistry
- Nature of the Amyloid-β Monomer and the Monomer-Oligomer EquilibriumSuman Nag, Bidyut Sarkar, Arkarup Bandyopadhyay, Bankanidhi Sahoo, Varun K. A. Sreenivasan, Mamata H. Kombrabail, Muralidharan Chandrakesan, Sudipta Maiti · 2011 · Journal of Biological Chemistry
- Amyloidogenesis of Natively Unfolded ProteinsVladimir Nikolaevich Uversky · 2008 · Current Alzheimer Research
- The presenilin-1 familial Alzheimer disease mutant P117L impairs neurogenesis in the hippocampus of adult micePaul H. Wen, Patrick R. Hof, Xiaoping Chen, Karen Gluck, Gregory Austin, Steven G. Younkin, Linda H. Younkin, Rita DeGasperi, Miguel A. Gama Sosa, Nikolaos K. R K Robakis et al. · 2004 · Experimental Neurology
- Therapeutic strategies for Alzheimer's diseaseMichael S. Wolfe · 2002 · Nature Reviews Drug Discovery
- Amyloid-β and τ serve antioxidant functions in the aging and Alzheimer brainMark A. Smith, Gemma Casadesús, James A. Joseph, George L. Perry · 2002 · Free Radical Biology and Medicine
- Inhibition of Calcineurin-mediated Endocytosis and α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptors Prevents Amyloid β Oligomer-induced Synaptic DisruptionZhao, Wei-Qin, Santini, Francesca, Breese, Robert, Ross, Dave, Zhang, Xiaohua Douglas, Stone, David J., Ferrer, Marc, Townsend, Matthew, Wolfe, Abigail L., Seager, Matthew A. et al. · 2010 · Journal of Biological Chemistry
- Calcium/calmodulin-dependent kinase II and Alzheimer’s diseaseGhosh, Anshua, Giese, Karl Peter · 2015 · Molecular Brain
- Angiotensin-Converting Enzyme Converts Amyloid β-Protein 1–42 (Aβ1–42) to Aβ1–40, and Its Inhibition Enhances Brain Aβ DepositionKun Zou, H. Yamaguchi, H. Akatsu, Takaaki Sakamoto, Mihee Ko, K. Mizoguchi, J. Gong, Wenxin Yu, Takayuki Yamamoto, K. Kosaka et al. · 2007 · Journal of Neuroscience
- In vivo oxidative stress in brain of Alzheimer disease transgenic mice: Requirement for methionine 35 in amyloid β-peptide of APPDavid Allan Butterfield, Verónica Galván, Miranda L. Bader Lange, Huidong Tang, Renã A. S. Robinson, Patricia R. Spilman, Joanna Fombonne, Olivia F. Gorostiza, Junli Zhang, Rukhsana Sultana A et al. · 2009 · Free Radical Biology and Medicine
- S100 Proteins in Alzheimer’s DiseaseCristóvão, Joana S., Gomes, Cláudio M. · 2019 · Frontiers in Neuroscience
- HIV-1 Tat inhibits neprilysin and elevates amyloid βHans C Rempel, Lynn Pulliam · 2005 · AIDS
- Amyloid Peptide ChannelsBruce L. Kagan, Rustam Azimov, R. Azimova · 2004 · The Journal of Membrane Biology
- Synapse-Associated Protein-97 Mediates α-Secretase ADAM10 Trafficking and Promotes Its ActivityElena E. Marcello, Fabrizio Gardoni, Daniela Mauceri, Stefano Romorini, Andreas Jeromin, Roberta Epis, Barbara Borroni, Flaminio Cattabeni, Carlo Sala, Alessandro Padovani et al. · 2007 · Journal of Neuroscience
- Models of β-Amyloid Ion Channels in the Membrane Suggest That Channel Formation in the Bilayer Is a Dynamic ProcessHyunbum Jang, Jie Zheng, Ruth Nussinov · 2007 · Biophysical Journal
- Crucial role of nonspecific interactions in amyloid nucleationAnđela Šarić, Yassmine Chebaro, Tuomas P. J. Knowles, Daan Frenkel · 2014 · Proceedings of the National Academy of Sciences
- Exosomes neutralize synaptic-plasticity-disrupting activity of Aβ assemblies in vivoKyongman An, Igor V. Klyubin, Youngkyu Kim, Jung Hoon Jung, Alexandra J. Mably, Seán O’Dowd, Timothy Lynch, Daniel Kanmert, Cynthia Ann Lemere, Gina M. Finan et al. · 2013 · Molecular Brain
- A Comparison of Three Fluorophores for the Detection of Amyloid Fibers and Prefibrillar Oligomeric Assemblies. ThT (Thioflavin T); ANS (1-Anilinonaphthalene-8-sulfonic Acid); and bisANS (4,4'-Dianilino-1,1'-binaphthyl-5,5'-disulfonic Acid).Nadine D. Younan, J. H. Viles · 2015 · Biochemistry
- A strategy for designing inhibitors of α ‐synuclein aggregation and toxicity as a novel treatment for Parkinson's disease and related disordersOmar M. A. El‐Agnaf, Katerina E. Paleologou, Brett Greer, Abdulmawala M. Abogrein, Jenny E. King, Sultan A. Salem, Nigel J. Fullwood, Fiona E. Benson, Rebecca Hewitt, Kirstie J. Ford et al. · 2004 · The FASEB Journal
- Selective Translational Control of the Alzheimer Amyloid Precursor Protein Transcript by Iron Regulatory Protein-1Hyun-Hee Cho, Catherine M. Cahill, Charles R. Vanderburg, Clemens R. Scherzer, Bin Wang, Xudong Huang, Jack T. Rogers · 2010 · Journal of Biological Chemistry
- The Oxidative Stress Metabolite 4-Hydroxynonenal Promotes Alzheimer Protofibril FormationSarah J. Siegel, Jan Bieschke, Evan T. Powers, Jeffery W. Kelly · 2007 · Biochemistry
- Huntingtin Bodies Sequester Vesicle-Associated Proteins by a Polyproline-Dependent InteractionZheng‐Hong Qin, Yumei Wang, Ellen Sapp, Benjamin Cuiffo, Erich E. Wanker, Michael R. Hayden, Kimberly B. Kegel, Neil Aronin M. D, Marian DiFiglia · 2004 · Journal of Neuroscience
- Role of the ubiquitin proteasome system in Alzheimer's diseaseSudarshan C. Upadhya, Ashok N. Hegde · 2007 · BMC Biochemistry
- Melatonin treatment restores mitochondrial function in Alzheimer’s mice: a mitochondrial protective role of melatonin membrane receptor signalingNatasa Dragicevic, Neil Copes, Gina O’Neal-Moffitt, Jingji Jin, Robert W. Buzzeo, Maggie Mamcarz, Jun Tan, Chuanhai Cao, James Olcese, Gary W. Arendash et al. · 2011 · Journal of Pineal Research
- Protein aggregation in disease: a role for folding intermediates forming specific multimeric interactionsArthur L. Horwich · 2002 · Journal of Clinical Investigation
- Neuronal Cell Death in Alzheimers Disease and a Neuroprotective Factor, HumaninNiikura, Takako, Tajima, Hirohisa, Kita, Yoshiko · 2006 · Current Neuropharmacology
- Neural compensation in older people with brain amyloid-β depositionJeremy A. Elman, Hwamee Oh, Cindee M. Madison, Suzanne L. Baker, Jacob W. Vogel, Shawn M. Marks, Sam Crowley, James P. O’Neil, William J. Jagust · 2014 · Nature Neuroscience
- Genetic reduction of striatal-enriched tyrosine phosphatase (STEP) reverses cognitive and cellular deficits in an Alzheimer’s disease mouse modelYongfang Zhang, Pradeep K. Kurup, Jian Xu, Nikisha Carty, Stephanie M. Fernandez, Haakon B. Nygaard, Christopher Pittenger, Paul Greengard, Stephen M. Strittmatter, Angus Clark Nairn et al. · 2010 · Proceedings of the National Academy of Sciences
- Direct characterization of amyloidogenic oligomers by single-molecule fluorescenceÁngel Orte, Neil R. Birkett, Richard W. Clarke, Glyn L. Devlin, Christopher Martin Dobson, David Klenerman · 2008 · Proceedings of the National Academy of Sciences
- Memantine Improves Spatial Learning in a Transgenic Mouse Model of Alzheimer’s DiseaseRimante Minkeviciene, Pradeep Banerjee, Heikki Tanila · 2004 · Journal of Pharmacology and Experimental Therapeutics
- Neuronal hyperactivity due to loss of inhibitory tone in APOE4 mice lacking Alzheimer’s disease-like pathologyNuriel, Tal, Angulo, Sergio L., Khan, Usman, Ashok, Archana, Chen, Qiuying, Figueroa, Helen Y., Emrani, Sheina, Liu, Li, Herman, Mathieu, Barrett, Geoffrey et al. · 2017 · Nature Communications
- Biochemical and biophysical features of both oligomer/fibril and cell membrane in amyloid cytotoxicityMassimo Stefani · 2010 · FEBS Journal
- A central role for dityrosine crosslinking of Amyloid-β in Alzheimer’s diseaseYoussra K. Al‐Hilaly, Thomas L. Williams, Maris Stewart-Parker, Lenzie K. Ford, Eldhose Skaria, Michael Cole, William Grant Bucher, Kyle L. Morris, Alaa Abdul Sada, Julian R. Thorpe et al. · 2013 · Acta Neuropathologica Communications
- Oligomeric Amyloid Decreases Basal Levels of Brain-Derived Neurotrophic factor (BDNF) mRNA via Specific Downregulation of BDNF Transcripts IV and V in Differentiated Human Neuroblastoma CellsDiego J. Garzon, Margaret L. Fahnestock · 2007 · Journal of Neuroscience
- Oligomeric amyloid-β peptide disrupts phosphatidylinositol-4,5-bisphosphate metabolismBerman, Diego E, Dall'Armi, Claudia, Voronov, Sergey V, McIntire, Laura Beth J, Zhang, Hong, Moore, Ann Z, Staniszewski, Agniezka, Arancio, Ottavio, Kim, Tae-Wan, Di Paolo, Gilbert · 2008 · Nature Neuroscience
- Mitochondrial dysfunction: the missing link between aging and sporadic Alzheimer’s diseaseAmandine Grimm, Kristina Friedland, Anne Eckert · 2015 · Biogerontology
- Amyloid Beta: Multiple Mechanisms of Toxicity and Only Some Protective Effects?Paul Carrillo‐Mora, Rogelio Luna, Laura Colín-Barenque · 2014 · Oxidative Medicine and Cellular Longevity
- Pathological Interface Between Oligomeric Alpha-Synuclein and Tau in SynucleinopathiesUrmi Sengupta, Marcos Jair Guerrero‐Munoz, Diana Laura Castillo‐Carranza, Cristian A. Lasagna‐Reeves, Julia E. Gerson, Adriana A. Paulucci-Holthauzen, Shashirekha Krishnamurthy, Malika Farhed, George R. Jackson, Rakez Kayed · 2015 · Biological Psychiatry
- Neprilysin-sensitive Synapse-associated Amyloid-β Peptide Oligomers Impair Neuronal Plasticity and Cognitive FunctionShu-Ming Huang, Akihiro Mouri, Hideko Kokubo, Ryuichi Nakajima, Takahiro Suemoto, Makoto Higuchi, Matthias Staufenbiel, Yukihiro Noda, Haruyasu Yamaguchi, Toshitaka Nabeshima et al. · 2006 · Journal of Biological Chemistry
- ‘Unfolding’ pathways in neurodegenerative diseaseMark S. Forman, Virginia M.‐Y. Lee, John Q. Trojanowski · 2003 · Trends in Neurosciences
- Fluid Biomarkers for Synaptic Dysfunction and LossCamporesi, Elena, Nilsson, Johanna, Brinkmalm, Ann, Becker, Bruno, Ashton, Nicholas J, Blennow, Kaj, Zetterberg, Henrik · 2020 · Biomarker Insights
- Peptidyl-prolyl cis–trans isomerase Pin1 in ageing, cancer and Alzheimer diseaseTae Ho Lee, Lucia Pastorino, Kun Ping Lu · 2011 · Expert Reviews in Molecular Medicine
- Toxic oligomers and islet beta cell death: guilty by association or convicted by circumstantial evidence?Sakeneh Zraika, Rebecca L. Hull, C. Bruce Verchere, Anne Clark, Kathryn J. Potter, Paul E. Fraser, Daniel P. Raleigh, Steven E. Kahn · 2010 · Diabetologia
- Phospholipase D2 Ablation Ameliorates Alzheimer's Disease-Linked Synaptic Dysfunction and Cognitive DeficitsTiago Gil Oliveira, Robin Chan, Huasong Tian, Mikaël Laredo, Guanghou Shui, Agnieszka Staniszewski, Hong Zhang, Lili Wang, Tae‐Wan Kim, Karen Duff et al. · 2010 · Journal of Neuroscience
- Interaction of the Molecular Chaperone DNAJB6 with Growing Amyloid-beta 42 (Aβ42) Aggregates Leads to Sub-stoichiometric Inhibition of Amyloid FormationCecilia Månsson, Paolo Arosio, Rasha Mohamed Hussein, Harm H. Kampinga, Reem M. Hashem, Wilbert C. Boelens, Christopher Martin Dobson, Tuomas P. J. Knowles, Sara Snogerup Linse, Cecilia Sundby Emanuelsson · 2014 · Journal of Biological Chemistry
- The neuropathogenic contributions of lysosomal dysfunctionBen A. Bahr, Jennifer Bendiske · 2002 · Journal of Neurochemistry
- RAGE and Alzheimer's Disease: A Progression Factor for Amyloid-β-Induced Cellular Perturbation?Shi Du Yan, Angelika Bierhaus, Peter P. Nawroth, David M. Stern · 2009 · Journal of Alzheimer s Disease
- Tannic Acid Is a Natural β-Secretase Inhibitor That Prevents Cognitive Impairment and Mitigates Alzheimer-like Pathology in Transgenic MiceTakashi Mori, Kavon P. Rezai-Zadeh, Naoki Koyama, Gary W. Arendash, Haruyasu Yamaguchi, Nobuto Kakuda, Yuko Horikoshi‐Sakuraba, Jun Tan, Terrence Town · 2012 · Journal of Biological Chemistry
- Size-dependent neurotoxicity of β-amyloid oligomersPaulius Čižas, Rima Budvytytė, Ramunė Morkūnienė, Radu Moldovan, Matteo Broccio, Mathias Lösche, Gediminas Niaura, Gintaras Valinčius, Vilmantė Borutaitė · 2010 · Archives of Biochemistry and Biophysics
- β-Amyloid Impairs AMPA Receptor Trafficking and Function by Reducing Ca2+/Calmodulin-dependent Protein Kinase II Synaptic DistributionZhenglin Gu, Wenhua Liu, Zhen Yan · 2009 · Journal of Biological Chemistry
- Lymphatics in Neurological Disorders: A Neuro-Lympho-Vascular Component of Multiple Sclerosis and Alzheimer’s Disease?Antoine Louveau, Sandro Dá Mesquita, Jonathan Kipnis · 2016 · Neuron
- Somatodendritic accumulation of Tau in Alzheimer's disease is promoted by Fyn‐mediated local protein translationChuanzhou Li, Jürgen Götz · 2017 · The EMBO Journal
- Hypotrichosis simplex of the scalp is associated with nonsense mutations in CDSN encoding corneodesmosinEtgar Levy‐Nissenbaum, Regina Christine Betz, Moshe Frydman, Michel Simon, Hadas Lahat, Tengiz Bakhan, Boleslaw Goldman, Anette Bygum, Monika Pierick, Axel M. Hillmer et al. · 2003 · Nature Genetics
- Protein aggregation and the ubiquitin proteasome pathway: gaining the UPPer hand on neurodegenerationSarah J Shoesmith Berke, Henry Lauris Paulson · 2003 · Current Opinion in Genetics & Development
- β-Amyloid Immunotherapy Prevents Synaptic Degeneration in a Mouse Model of Alzheimer's DiseaseButtini, Manuel, Masliah, Eliezer, Barbour, Robin, Grajeda, Henry, Motter, Ruth, Johnson-Wood, Kelly, Khan, Karen, Seubert, Peter, Freedman, Stephen, Schenk, Dale et al. · 2005 · The Journal of Neuroscience
- Kinetic control of dimer structure formation in amyloid fibrillogenesisWonmuk Hwang, Shuguang Zhang, Roger Dale Kamm, Martin Karplus · 2004 · Proceedings of the National Academy of Sciences
- Structural features and cytotoxicity of amyloid oligomers: Implications in Alzheimer's disease and other diseases with amyloid depositsMassimo Stefani · 2012 · Progress in Neurobiology
- Synaptic Depression and Aberrant Excitatory Network Activity in Alzheimer’s Disease: Two Faces of the Same Coin?Jorge J. Palop, Lennart Mucke · 2009 · NeuroMolecular Medicine
- Environmental Novelty Activates β2-Adrenergic Signaling to Prevent the Impairment of Hippocampal LTP by Aβ OligomersShaomin Li, Ming Jin, Dainan Zhang, Ting Yang, Thomas Koeglsperger, Hongjun Fu, Dennis J. Selkoe · 2013 · Neuron
- Differential Regulation of Amyloid-β Endocytic Trafficking and Lysosomal Degradation by Apolipoprotein E IsoformsJie Li, Takahisa Kanekiyo, Mitsuru Shinohara, Yun‐wu Zhang, Mary Jo LaDu, Huaxi Xu, Guojun Bu · 2012 · Journal of Biological Chemistry