Naturally secreted oligomers of amyloid β protein potently inhibit hippocampal long-term potentiation in vivo

Walsh, Dominic M., Klyubin, Igor, Fadeeva, Julia V., Cullen, William K., Anwyl, Roger, Wolfe, Michael S., Rowan, Michael J., Selkoe, Dennis J.·2002·Nature

Cited by (1,067)

Items 301–400 of 1,067

  1. Dysregulation of Histone Acetylation in the APP/PS1 Mouse Model of Alzheimer's Disease
    Yitshak I. Francis, Mauro Fà, Haider Ashraf, Hong Zhang, Agnieszka Staniszewski, David S. Latchman, Ottavio Arancio · 2009 · Journal of Alzheimer s Disease
  2. Temporal memory deficits in Alzheimer’s mouse models: Rescue by genetic deletion of BACE1
    Ohno, Masuo, Chang, Lei, Tseng, Wilbur, Oakley, Holly, Citron, Martin, Klein, William L., Vassar, Robert, Disterhoft, John F. · 2006 · European Journal of Neuroscience
  3. The Ratio of Monomeric to Aggregated Forms of Aβ40 and Aβ42 Is an Important Determinant of Amyloid-β Aggregation, Fibrillogenesis, and Toxicity
    Jan, Asad, Gokce, Ozgun, Luthi-Carter, Ruth, Lashuel, Hilal A. · 2008 · Journal of Biological Chemistry
  4. Amyloid-β Dynamics Correlate with Neurological Status in the Injured Human Brain
    Brody, David L., Magnoni, Sandra, Schwetye, Kate E., Spinner, Michael L., Esparza, Thomas J., Stocchetti, Nino, Zipfel, Gregory J., Holtzman, David M. · 2008 · Science
  5. Alzheimer’s disease: pathological mechanisms and the beneficial role of melatonin
    Sergio Rosales‐Corral, Darı́o Acuña-Castroviejo, Ana M. Coto‐Montes, José Antonio Boga, Lucien C. Manchester, Lorena Fuentes‐Broto, Ahmet Korkmaz, Shuran Ma, Dun‐ Xian Tan, Russel Joseph Reiter · 2011 · Journal of Pineal Research
  6. Roles of molecular chaperones in protein misfolding diseases
    José M. Barral, Sarah A. Broadley, Gregor Schaffar, F. Ulrich Hartl · 2004 · Seminars in Cell and Developmental Biology
  7. Activation of Wnt signaling by lithium and rosiglitazone reduced spatial memory impairment and neurodegeneration in brains of an APPswe/PSEN1ΔE9 mouse model of Alzheimer's disease
    Enrique M. Toledo, Nibaldo C. Inestrosa · 2009 · Molecular Psychiatry
  8. Deciphering the Genetic Basis of Alzheimer's Disease
    Dennis J. Selkoe, Marcia Berman Podlisny · 2002 · Annual Review of Genomics and Human Genetics
  9. α‐Synuclein oligomers and clinical implications for Parkinson disease
    Lorraine V. Kalia, Suneil Kumar Kalia, Pamela J. McLean, Andrés M. Lozano, Anthony Edward Lang · 2012 · Annals of Neurology
  10. Minocycline Attenuates Neuronal Cell Death and Improves Cognitive Impairment in Alzheimer's Disease Models
    Yoori Choi, Hye‐Sun Kim, Ki Young Shin, Eun‐Mee Kim, Minji Kim, Hyun-Soo Kim, Cheol Hyoung Park, Yun Ha Jeong, Jongman Yoo, Jean‐Pyo Lee et al. · 2007 · Neuropsychopharmacology
  11. The amyloid cascade hypothesis: an updated critical review
    Kasper P. Kepp, Nikolaos K. R K Robakis, Poul Flemming Høilund‐Carlsen, Stefano Luca Sensi, Bryce Vissel · 2023 · Brain
  12. Interaction between Human Prion Protein and Amyloid-β (Aβ) Oligomers
    Shugui Chen, Satya Prakash Yadav, Witold K. Surewicz · 2010 · Journal of Biological Chemistry
  13. Are mitochondria critical in the pathogenesis of Alzheimer's disease?
    P. Hemachandra Reddy, M. Flint Beal · 2005 · Brain Research Reviews
  14. Prion-like disorders: blurring the divide between transmissibility and infectivity
    Mimi Cushman-Nick, Brian S. Johnson, Oliver D. King, Aaron D. Gitler, James Shorter · 2010 · Journal of Cell Science
  15. Aging in Down Syndrome and the Development of Alzheimer's Disease Neuropathology
    Head, Elizabeth, T. Lott, Ira, M. Wilcock, Donna, A. Lemere, Cynthia · 2015 · Current Alzheimer Research
  16. Oxidative damage in neurodegeneration: roles in the pathogenesis and progression of Alzheimer disease
    Marzia Perluigi A, Fabio Di Domenico, David Allan Butterfield · 2023 · Physiological Reviews
  17. Age-Dependent Neurodegeneration and Alzheimer-Amyloid Plaque Formation in Transgenic Drosophila
    Isabell Greeve, Doris Kretzschmar, Jakob‐Andreas Tschäpe, Anika Beyn, Claire Brellinger, Michaela Schweizer, Roger M. Nitsch, Rita Reifegerste · 2004 · Journal of Neuroscience
  18. Elucidation of Primary Structure Elements Controlling Early Amyloid β-Protein Oligomerization
    Gal Bitan, Sabrina S. Vollers, David B. Teplow · 2003 · Journal of Biological Chemistry
  19. Certain Inhibitors of Synthetic Amyloid β-Peptide (Aβ) Fibrillogenesis Block Oligomerization of Natural Aβ and Thereby Rescue Long-Term Potentiation
    Dominic M. Walsh, Matthew Townsend, Marcia Berman Podlisny, Ganesh M. Shankar, Julia V. Fadeeva, Omar M. A. El‐Agnaf, Dean M. Hartley, Dennis J. Selkoe · 2005 · Journal of Neuroscience
  20. Generation of antibodies specific for β-amyloid by vaccination of patients with Alzheimer disease
    Christoph Höck, Uwe Konietzko, Andreas Papassotiropoulos, Axel Wollmer, Johannes Rolf Streffer, Ruth C. von Rotz, Gabriela E. Davey, Eva Moritz, Roger M. Nitsch · 2002 · Nature Medicine
  21. Reduction of Soluble Aβ and Tau, but Not Soluble Aβ Alone, Ameliorates Cognitive Decline in Transgenic Mice with Plaques and Tangles
    Salvatore Oddo, Vitaly Vasilevko, Antonella Caccamo, Masashi Kitazawa, David H. Cribbs, Frank M. LaFerla · 2006 · Journal of Biological Chemistry
  22. Age matters
    James E. McCutcheon, Michela Marinelli · 2009 · European Journal of Neuroscience
  23. Substrate-targeting γ-secretase modulators
    Thomas L. Kukar, Thomas B. Ladd, Maralyssa A. Bann, Patrick C. Fraering, Rajeshwar Narlawar, Ghulam M. Maharvi, Brent Healy, Robert Chapman, Alfred T. Welzel, Robert W. Price et al. · 2008 · Nature
  24. Safety and biomarker effects of solanezumab in patients with Alzheimer's disease
    Martin Rhys Farlow, Steven Edward Arnold, Christopher H. van Dyck, Paul S. S. Aisen, B. Joy Snider, Anton P. Porsteinsson, Stuart W. Friedrich, Robert A. Dean, Celedon Gonzales, Gopalan Sethuraman et al. · 2012 · Alzheimer s & Dementia
  25. Increasing Cu bioavailability inhibits Aβ oligomers and tau phosphorylation
    Peter John Crouch, Lin Wai Hung, Paul Anthony Adlard, Mikhalina Cortés, Varsha Lal, Gulay Filiz, Keyla A. Perez, Milawaty Nurjono, Aphrodite Caragounis, Tai Du et al. · 2009 · Proceedings of the National Academy of Sciences
  26. Transmembrane glycine zippers: Physiological and pathological roles in membrane proteins
    Sanguk Kim, Tae‐Joon Jeon, Amit Oberai, Duan Yang, Jacob J. Schmidt, James U. Bowie · 2005 · Proceedings of the National Academy of Sciences
  27. The Pericyte: A Forgotten Cell Type with Important Implications for A lzheimer's Disease?
    Ethan A. Winkler, Abhay P. Sagare, Berislav V. Zloković · 2014 · Brain Pathology
  28. Amyloid β-protein oligomers and Alzheimer’s disease
    Hayden, Eric Y, Teplow, David B · 2013 · Alzheimer's Research & Therapy
  29. Alzheimer's disease in Down syndrome: Neurobiology and risk
    Warren B. Zigman, Ira T. Lott · 2007 · Mental Retardation and Developmental Disabilities Research Reviews
  30. Soluble β-Amyloid1-40Induces NMDA-Dependent Degradation of Postsynaptic Density-95 at Glutamatergic Synapses
    Francesco Roselli, Marilyn Tirard, Jie Lu, Peter Hutzler, P. Lamberti, Paolo Livrea, Maria A. Morabito, Osborne F. X. Almeida · 2005 · Journal of Neuroscience
  31. RETRACTED: The Complex PrPc-Fyn Couples Human Oligomeric Aβ with Pathological Tau Changes in Alzheimer's Disease
    Megan E. Larson, Mathew A. Sherman, Fatou Amar, Mario Nuvolone, Julie A. Schneider, David Alan Bennett, Adriano Aguzzi, Sylvain Lesné · 2012 · Journal of Neuroscience · Retracted
  32. Clearance of cerebral Aβ in Alzheimer’s disease: reassessing the role of microglia and monocytes
    Leah R. Zuroff, David A. Daley, Keith L. Black, Maya Koronyo‐Hamaoui · 2017 · Cellular and Molecular Life Sciences
  33. Chapter 3 Interactions Between Heparan Sulfate and Proteins—Design and Functional Implications
    Ulf Lindahl, Jin‐Ping Li · 2009 · International review of cytology
  34. TLR4 mutation reduces microglial activation, increases Aβ deposits and exacerbates cognitive deficits in a mouse model of Alzheimer’s disease
    Song, Min, Jin, JingJi, Lim, Jeong-Eun, Kou, Jinghong, Pattanayak, Abhinandan, Rehman, Jamaal A, Kim, Hong-Duck, Tahara, Kazuki, Lalonde, Robert, Fukuchi, Ken-ichiro · 2011 · Journal of Neuroinflammation
  35. Studies of the aggregation of mutant proteins in vitro provide insights into the genetics of amyloid diseases
    Fabrizio Chiti, Martino Calamai, Niccolò Taddei, Massimo Stefani, Giampietro Ramponi, Christopher Martin Dobson · 2002 · Proceedings of the National Academy of Sciences
  36. Interaction of Endogenous Tau Protein with Synaptic Proteins Is Regulated by N-Methyl-d-aspartate Receptor-dependent Tau Phosphorylation*
    Mondragón-Rodríguez, Siddhartha, Trillaud-Doppia, Emilie, Dudilot, Anthony, Bourgeois, Catherine, Lauzon, Michel, Leclerc, Nicole, Boehm, Jannic · 2012 · Journal of Biological Chemistry
  37. Retinoic Acid Attenuates β-Amyloid Deposition and Rescues Memory Deficits in an Alzheimer's Disease Transgenic Mouse Model
    Ding, Yun, Qiao, Aimin, Wang, Ziqing, Goodwin, J. Shawn, Lee, Eun-Sook, Block, Michelle L., Allsbrook, Matthew, McDonald, Michael P., Fan, Guo-Huang · 2008 · The Journal of Neuroscience
  38. Contributions of Brain Insulin Resistance and Deficiency in Amyloid-Related Neurodegeneration in Alzheimerʼs Disease
    de la Monte, Suzanne M. · 2012 · Drugs
  39. The biological pathways of Alzheimer disease: a review
    Marco Calabrò, Carmela Rinaldi, Giuseppe Santoro, Concetta Crisafulli · 2020 · AIMS neuroscience
  40. Inhibition of Amyloid Peptide Fibrillation by Inorganic Nanoparticles: Functional Similarities with Proteins
    Seong Il Yoo, Ming Yang, Jeffrey Brender, Subramanian Vivekanandan, Kai Sun, Nam Eok Joo, Soo‐Hwan Jeong, Ayyalusamy Ramamoorthy, Nicholas A. Kotov · 2011 · Angewandte Chemie International Edition
  41. A mechanistic hypothesis for the impairment of synaptic plasticity by soluble Aβ oligomers from Alzheimer’s brain
    Shaomin Li, Dennis J. Selkoe · 2020 · Journal of Neurochemistry
  42. The Glutamatergic System and Alzheimer???s Disease
    David Allan Butterfield, Chava B. Pocernich · 2003 · CNS Drugs
  43. Targeting Cellular Prion Protein Reverses Early Cognitive Deficits and Neurophysiological Dysfunction in Prion-Infected Mice
    Giovanna R. Mallucci, Melanie D. White, Michael Farmer, Andrew Dickinson, Husna Khatun, Andrew D. Powell, Sebastian Brandner, John G. R. Jefferys, John Collinge · 2007 · Neuron
  44. The role of metallobiology and amyloid-β peptides in Alzheimer's disease
    Roberts, Blaine R., Ryan, Timothy M., Bush, Ashley I., Masters, Colin L., Duce, James A. · 2012 · Journal of Neurochemistry
  45. High‐molecular‐weight β‐amyloid oligomers are elevated in cerebrospinal fluid of Alzheimer patients
    Fukumoto, Hiroaki, Tokuda, Takahiko, Kasai, Takashi, Ishigami, Noriko, Hidaka, Hiroya, Kondo, Masaki, Allsop, David, Nakagawa, Masanori · 2010 · The FASEB Journal
  46. The ubiquitin‐proteasome system in Alzheimer's disease
    Salvatore Oddo · 2008 · Journal of Cellular and Molecular Medicine
  47. Part II: α-synuclein and its molecular pathophysiological role in neurodegenerative disease
    Kumlesh Kumar Dev · 2003 · Neuropharmacology
  48. Tyrosine gated electron transfer is key to the toxic mechanism of Alzheimer's disease β‐amyloid
    Kevin Jeffrey Barnham, Fredrik Hæffner, Giuseppe D. Ciccotosto, Cyril C. Curtain, Deborah J. Tew, Christine Mavros, Konrad T. Beyreuther, Darryl Carrington, Colin Louis Masters, Robert A. Cherny et al. · 2004 · The FASEB Journal
  49. Amyloid β‐peptide interactions with neuronal and glial cell plasma membrane: binding sites and implications for Alzheimer's disease
    Yann Verdier, Márta Zarándi, Botond Penke · 2004 · Journal of Peptide Science
  50. Huntington's Disease
    Steven M. Finkbeiner · 2011 · Cold Spring Harbor Perspectives in Biology
  51. Preparation and characterization of toxic Aβ aggregates for structural and functional studies in Alzheimer's disease research
    Asad Jan, Dean M. Hartley, Hilal Ahmed Lashuel · 2010 · Nature Protocols
  52. Minute quantities of misfolded mutant superoxide dismutase‐1 cause amyotrophic lateral sclerosis
    P. Andreas Jonsson, Karin Ernhill, Peter Munch Andersen, Daniel Bergemalm, Thomas Brännström, Ole Gredal, Peter Nilsson, Stefan L. Marklund · 2003 · Brain
  53. Intracellular Aβ and cognitive deficits precede β-amyloid deposition in transgenic arcAβ mice
    Knobloch, Marlen, Konietzko, Uwe, Krebs, Danielle C., Nitsch, Roger M. · 2007 · Neurobiology of Aging
  54. The Arctic Alzheimer mutation facilitates early intraneuronal Aβ aggregation and senile plaque formation in transgenic mice
    Lord, Anna, Kalimo, Hannu, Eckman, Chris, Zhang, Xiao-Qun, Lannfelt, Lars, Nilsson, Lars N.G. · 2006 · Neurobiology of Aging
  55. Presynaptic Localization of Neprilysin Contributes to Efficient Clearance of Amyloid-β Peptide in Mouse Brain
    Nobuhisa Iwata, Hiroaki Mizukami, Keiro Shirotani, Yoshie Takaki, Shin‐ichi Muramatsu, Bao Lu, Norma P. Gerard, Craig J Gerard, Keiya Ozawa, Takaomi C. Saido · 2004 · Journal of Neuroscience
  56. The prion protein as a receptor for amyloid-β
    Kessels, Helmut W., Nguyen, Louis N., Nabavi, Sadegh, Malinow, Roberto · 2010 · Nature
  57. Inhibition of γ‐secretase causes increased secretion of amyloid precursor protein C‐terminal fragments in association with exosomes
    Robyn A. Sharples, Laura J. Vella, Rebecca M. Nisbet, Ryan Naylor, Keyla A. Perez, Kevin Jeffrey Barnham, Colin Louis Masters, Andrew Francis Hill · 2008 · The FASEB Journal
  58. Amyloid-β Binds to the Extracellular Cysteine-rich Domain of Frizzled and Inhibits Wnt/β-Catenin Signaling
    Margaret H. Magdesian, Milena Carvalho, Fábio A. Mendes, Leonardo Martins Saraiva, María A. Juliano, Luiz Juliano, José Garcia-Abreu, Sergio Teixeira Ferreira · 2008 · Journal of Biological Chemistry
  59. Acute Impairment of Mitochondrial Trafficking by β-Amyloid Peptides in Hippocampal Neurons
    Yanfang Rui, Priyanka Tiwari, Zuoping Xie, James Q. Zheng · 2006 · Journal of Neuroscience
  60. Intracellular accumulation of amyloid-beta – a predictor for synaptic dysfunction and neuron loss in Alzheimer’s disease
    Bayer · 2010 · Frontiers in Aging Neuroscience
  61. Astrocyte energy and neurotransmitter metabolism in Alzheimer’s disease: Integration of the glutamate/GABA-glutamine cycle
    Jens Velde Andersen, Arne Schousboe, Alexei Verkhratsky · 2022 · Progress in Neurobiology
  62. Neurovascular Dysfunction and Faulty Amyloid  -Peptide Clearance in Alzheimer Disease
    Sagare, A. P., Bell, R. D., Zlokovic, B. V. · 2012 · Cold Spring Harbor Perspectives in Medicine
  63. Active and passive immunotherapy for neurodegenerative disorders
    Brody, David L., Holtzman, David M. · 2008 · Annual Review of Neuroscience
  64. Biomarkers of oxidative and nitrosative damage in Alzheimer's disease and mild cognitive impairment
    Francesca Mangialasche, Maria Cristina Polidori, Roberto Monastero, Sara Ercolani, Cecilia Camarda, Roberta Cecchetti, Patrizia Mecocci · 2009 · Ageing Research Reviews
  65. Amyloid-β as a Modulator of Synaptic Plasticity
    Mordhwaj Singh Parihar, Gregory J. Brewer · 2010 · Journal of Alzheimer s Disease
  66. A 3D human brain–like tissue model of herpes-induced Alzheimer’s disease
    Cairns, Dana M., Rouleau, Nicolas, Parker, Rachael N., Walsh, Katherine G., Gehrke, Lee, Kaplan, David L. · 2020 · Science Advances
  67. Amyloid Fibrils of Mammalian Prion Protein Are Highly Toxic to Cultured Cells and Primary Neurons
    Vera Novitskaya, Olga V. Bocharova, Igor B. Bronstein, Ilia V. Baskakov · 2006 · Journal of Biological Chemistry
  68. Conformational transition of amyloid β-peptide
    Yechun Xu, Jianhua Shen, Xiaomin Luo, Weiliang Zhu, Kaixian Chen, Jianpeng Ma, Hualiang Jiang · 2005 · Proceedings of the National Academy of Sciences
  69. Prefibrillar Amyloid Aggregates Could Be Generic Toxins in Higher Organisms
    Serena Baglioni, Fiorella Casamenti, Monica Bucciantini, Leila M. Luheshi, Niccolò Taddei, Fabrizio Chiti, Christopher Martin Dobson, Massimo Stefani · 2006 · Journal of Neuroscience
  70. Selectively Reduced Expression of Synaptic Plasticity-Related Genes in Amyloid Precursor Protein + Presenilin-1 Transgenic Mice
    Dickey, Chad A., Loring, Jeanne F., Montgomery, Julia, Gordon, Marcia N., Eastman, P. Scott, Morgan, Dave · 2003 · The Journal of Neuroscience
  71. Females exhibit more extensive amyloid, but not tau, pathology in an Alzheimer transgenic model
    Hirata-Fukae, Chiho, Li, Hui-Fang, Hoe, Hyang-Sook, Gray, Audrey J., Minami, S. Sakura, Hamada, Katsuyoshi, Niikura, Takako, Hua, Fang, Tsukagoshi-Nagai, Hiroe, Horikoshi-Sakuraba, Yuko et al. · 2008 · Brain Research
  72. The cellular prion protein mediates neurotoxic signalling of β‐sheet‐rich conformers independent of prion replication
    Ulrike K. Resenberger, Anja Harmeier, Andreas C. Woerner, Jessica L. Goodman, Veronika Müller, Rajaraman Krishnan, R. Martin Vabulas, Hans A. Kretzschmar, Susan Lee Lindquist, F. Ulrich Hartl et al. · 2011 · The EMBO Journal
  73. Bivalent Brain Shuttle Increases Antibody Uptake by Monovalent Binding to the Transferrin Receptor
    Hultqvist, Greta, Syvänen, Stina, Fang, Xiaotian T, Lannfelt, Lars, Sehlin, Dag · 2017 · Theranostics
  74. Mechanisms of Aβ mediated neurodegeneration in Alzheimer's disease
    Peter John Crouch, Susan-Marie E. Harding, Anthony Robert White, James Camakaris, Ashley Ian Bush, Colin Louis Masters · 2007 · The International Journal of Biochemistry & Cell Biology
  75. SOD1 (Copper/Zinc Superoxide Dismutase) Deficiency Drives Amyloid β Protein Oligomerization and Memory Loss in Mouse Model of Alzheimer Disease
    Murakami, Kazuma, Murata, Nakaba, Noda, Yoshihiro, Tahara, Shoichi, Kaneko, Takao, Kinoshita, Noriaki, Hatsuta, Hiroyuki, Murayama, Shigeo, Barnham, Kevin J., Irie, Kazuhiro et al. · 2011 · Journal of Biological Chemistry
  76. Involvement of p38 MAPK in Synaptic Function and Dysfunction
    Chiara Falcicchia, Francesca Tozzi, Ottavio Arancio, Daniel Martin Watterson, Nicola Origlia · 2020 · International Journal of Molecular Sciences
  77. Hydrogen Peroxide Is Generated during the Very Early Stages of Aggregation of the Amyloid Peptides Implicated in Alzheimer Disease and Familial British Dementia
    Brian J. Tabner, Omar M. A. El‐Agnaf, Stuart Turnbull, Matthew J. German, Katerina E. Paleologou, Yoshihito Hayashi, Leanne J. Cooper, Nigel J. Fullwood, David Allsop · 2005 · Journal of Biological Chemistry
  78. Brain Slices as Models for Neurodegenerative Disease and Screening Platforms to Identify Novel Therapeutics
    Seongeun Cho, Andrew Wood, Mark R. Bowlby · 2007 · Current Neuropharmacology
  79. Trace metal contamination initiates the apparent auto-aggregation, amyloidosis, and oligomerization of Alzheimer?s A? peptides
    Xudong Huang, Craig Atwood, Robert D. Moir, Mariana A. Hartshorn, Rudolph E. Tanzi, Ashley Ian Bush · 2004 · JBIC Journal of Biological Inorganic Chemistry
  80. β-Amyloid-induced Dynamin 1 Degradation Is Mediated by N-Methyl-D-Aspartate Receptors in Hippocampal Neurons
    Brent L. Kelly, Adriana Ferreira · 2006 · Journal of Biological Chemistry
  81. Amyloid-β and Mitochondria in Aging and Alzheimer's Disease: Implications for Synaptic Damage and Cognitive Decline
    P. Hemachandra Reddy, Maria Mańczak, Peizhong Mao, Marcus J. Calkins, Arubala P. Reddy, Ulziibat P. Shirendeb · 2010 · Journal of Alzheimer s Disease
  82. Exercise alters the immune profile in Tg2576 Alzheimer mice toward a response coincident with improved cognitive performance and decreased amyloid
    Kathryn E. Nichol, Wayne W. Poon, Anna I. Parachikova, David H. Cribbs, Charles G. Glabe, Carl W. Cotman · 2008 · Journal of Neuroinflammation
  83. Environmental Enrichment Exacerbates Amyloid Plaque Formation in a Transgenic Mouse Model of Alzheimer Disease
    Joanna L. Jankowsky, Guilian M. Xu, David Fromholt, Victoria Gonzales, David Borchelt · 2003 · Journal of Neuropathology & Experimental Neurology
  84. Amyloidosis in Alzheimer’s Disease: Pathogeny, Etiology, and Related Therapeutic Directions
    Ma, Chen, Hong, Fenfang, Yang, Shulong · 2022 · Molecules
  85. Molecular mechanisms for Alzheimer's disease: implications for neuroimaging and therapeutics
    Colin Louis Masters, Roberto Cappai, Kevin Jeffrey Barnham, Victor L. Villemagne · 2006 · Journal of Neurochemistry
  86. Disulphide-reduced superoxide dismutase-1 in CNS of transgenic amyotrophic lateral sclerosis models
    P. Andreas Jonsson, Karin S. Graffmo, Peter Munch Andersen, Thomas Brännström, Mikael J. Lindberg, Mikael Oliveberg, Stefan L. Marklund · 2005 · Brain
  87. Accumulation of amyloid-β by astrocytes result in enlarged endosomes and microvesicle-induced apoptosis of neurons
    Söllvander, Sofia, Nikitidou, Elisabeth, Brolin, Robin, Söderberg, Linda, Sehlin, Dag, Lannfelt, Lars, Erlandsson, Anna · 2016 · Molecular Neurodegeneration
  88. Protein Folding and Aggregation into Amyloid: The Interference by Natural Phenolic Compounds
    Massimo Stefani, Stefania Rigacci · 2013 · International Journal of Molecular Sciences
  89. Mixtures of Wild-type and a Pathogenic (E22G) Form of Aβ40 in Vitro Accumulate Protofibrils, Including Amyloid Pores
    Hilal Ahmed Lashuel, Dean M. Hartley, Benjamin M. Petre, Joseph S. Wall, Martha N. Simon, Thomas Walz, Peter T. Lansbury · 2003 · Journal of Molecular Biology
  90. An infrared spectroscopy approach to follow β-sheet formation in peptide amyloid assemblies
    Jongcheol Seo, Waldemar Hoffmann, Stephan Warnke, Xing Huang, Sandy Gewinner, Wieland Schöllkopf, Michael T. Bowers, Gert von Helden, Kevin Pagel · 2016 · Nature Chemistry
  91. iPSC-Based Compound Screening and In Vitro Trials Identify a Synergistic Anti-amyloid β Combination for Alzheimer’s Disease
    Kondo, Takayuki, Imamura, Keiko, Funayama, Misato, Tsukita, Kayoko, Miyake, Michiyo, Ohta, Akira, Woltjen, Knut, Nakagawa, Masato, Asada, Takashi, Arai, Tetsuaki et al. · 2017 · Cell Reports
  92. Progranulin protects against amyloid β deposition and toxicity in Alzheimer's disease mouse models
    Minami, S Sakura, Min, Sang-Won, Krabbe, Grietje, Wang, Chao, Zhou, Yungui, Asgarov, Rustam, Li, Yaqiao, Martens, Lauren H, Elia, Lisa P, Ward, Michael E et al. · 2014 · Nature Medicine
  93. The role of mTOR signaling in Alzheimer disease
    Salvatore Oddo · 2012 · Frontiers in Bioscience-Scholar
  94. A decade of modeling Alzheimer's disease in transgenic mice
    MCGOWAN, E, ERIKSEN, J, HUTTON, M · 2006 · Trends in Genetics
  95. PARP-1 involvement in neurodegeneration: A focus on Alzheimer’s and Parkinson’s diseases
    Sara Martire, Luciana Mosca, Maria D’Erme · 2015 · Mechanisms of Ageing and Development
  96. Neurotoxic effect of oligomeric and fibrillar species of amyloid-beta peptide 1-42: Involvement of endoplasmic reticulum calcium release in oligomer-induced cell death
    Resende, R., Ferreiro, E., Pereira, C., Resende de Oliveira, C. · 2008 · Neuroscience
  97. Membrane Protein Structure, Function, and Dynamics: a Perspective from Experiments and Theory
    Cournia, Zoe, Allen, Toby W., Andricioaei, Ioan, Antonny, Bruno, Baum, Daniel, Brannigan, Grace, Buchete, Nicolae-Viorel, Deckman, Jason T., Delemotte, Lucie, del Val, Coral et al. · 2015 · The Journal of Membrane Biology
  98. Amyloid β Oligomers (Aβ 1–42 Globulomer) Suppress Spontaneous Synaptic Activity by Inhibition of P/Q-Type Calcium Currents
    Volker Nimmrich, Christiane Grimm, Andreas Draguhn, Stefan Barghorn, Alexander Lehmann, Hans Schoemaker, Heinz Hillen, Gerhard Groß, Ulrich Ebert, Claus Bruehl · 2008 · Journal of Neuroscience
  99. JNK3 Perpetuates Metabolic Stress Induced by Aβ Peptides
    Sung Ok Yoon, Dong Ju Park, Jae Cheon Ryu, Hatice Gülçin Özer, Chhavy Tep, Yong Jae Shin, Tae Hee Lim, Lucia Pastorino, Ajaya Jang Kunwar, James C. Walton et al. · 2012 · Neuron
  100. Emerging Concepts in Alzheimer's Disease
    Harry V. Vinters · 2014 · Annual Review of Pathology Mechanisms of Disease