Naturally secreted oligomers of amyloid β protein potently inhibit hippocampal long-term potentiation in vivo
Walsh, Dominic M., Klyubin, Igor, Fadeeva, Julia V., Cullen, William K., Anwyl, Roger, Wolfe, Michael S., Rowan, Michael J., Selkoe, Dennis J.·2002·Nature
DOI 10.1038/416535a
Cited by (1,067)
Items 101–200 of 1,067
- The Aging BrainYankner, Bruce A., Lu, Tao, Loerch, Patrick · 2008 · Annual Review of Pathology: Mechanisms of Disease
- Bioinorganic Chemistry of Alzheimer’s DiseaseKasper P. Kepp · 2012 · Chemical Reviews
- Soluble Aβ Oligomers Inhibit Long-Term Potentiation through a Mechanism Involving Excessive Activation of Extrasynaptic NR2B-Containing NMDA ReceptorsShaomin Li, Ming Jin, Thomas Koeglsperger, Nina E. Shepardson, Ganesh M. Shankar, Dennis J. Selkoe · 2011 · Journal of Neuroscience
- Cell-to-cell transmission of pathogenic proteins in neurodegenerative diseasesGuo, Jing L, Lee, Virginia M Y · 2014 · Nature Medicine
- Alzheimer’s disease and the basal forebrain cholinergic system: relations to β-amyloid peptides, cognition, and treatment strategiesDaniel S. Auld, Tom J. Kornecook, Stéphane Bastianetto, Rémi Quirion · 2002 · Progress in Neurobiology
- Widespread protein aggregation as an inherent part of aging in C. elegansDavid, Della C., Ollikainen, Noah, Trinidad, Jonathan C., Cary, Michael P., Burlingame, Alma L., Kenyon, Cynthia · 2010 · PLoS Biology
- Alzheimer amyloid-β oligomer bound to postsynaptic prion protein activates Fyn to impair neuronsJi Won Um, Haakon B. Nygaard, Jacqueline K. Heiss, Mikhail A. Kostylev, Massimiliano Stagi, Alexander O. Vortmeyer, Thomas Wısnıewskı, Erik C. Gunther, Stephen M. Strittmatter · 2012 · Nature Neuroscience
- Inhibitors of Class 1 Histone Deacetylases Reverse Contextual Memory Deficits in a Mouse Model of Alzheimer's DiseaseKilgore, Mark, Miller, Courtney A, Fass, Daniel M, Hennig, Krista M, Haggarty, Stephen J, Sweatt, J David, Rumbaugh, Gavin · 2010 · Neuropsychopharmacology
- Protection of synapses against Alzheimer's-linked toxins: Insulin signaling prevents the pathogenic binding of Aβ oligomersDe Felice, Fernanda G., Vieira, Marcelo N. N., Bomfim, Theresa R., Decker, Helena, Velasco, Pauline T., Lambert, Mary P., Viola, Kirsten L., Zhao, Wei-Qin, Ferreira, Sergio T., Klein, William L. · 2009 · Proceedings of the National Academy of Sciences
- Amyloid-β/Fyn–Induced Synaptic, Network, and Cognitive Impairments Depend on Tau Levels in Multiple Mouse Models of Alzheimer's DiseaseRoberson, Erik D., Halabisky, Brian, Yoo, Jong W., Yao, Jinghua, Chin, Jeannie, Yan, Fengrong, Wu, Tiffany, Hamto, Patricia, Devidze, Nino, Yu, Gui-Qiu et al. · 2011 · The Journal of Neuroscience
- Detection of oligomeric forms of α‐synuclein protein in human plasma as a potential biomarker for Parkinson's diseaseEl‐Agnaf, Omar M. A., Salem, Sultan A., Paleologou, Katerina E., Curran, Martin D., Gibson, Mark J., Court, Jennifer A., Schlossmacher, Michael G., Allsop, David · 2006 · The FASEB Journal
- A disintegrin-metalloproteinase prevents amyloid plaque formation and hippocampal defects in an Alzheimer disease mouse modelPostina, Rolf, Schroeder, Anja, Dewachter, Ilse, Bohl, Juergen, Schmitt, Ulrich, Kojro, Elzbieta, Prinzen, Claudia, Endres, Kristina, Hiemke, Christoph, Blessing, Manfred et al. · 2004 · Journal of Clinical Investigation
- Nose-to-brain drug delivery: An update on clinical challenges and progress towards approval of anti-Alzheimer drugsAgrawal, Mukta, Saraf, Swarnlata, Saraf, Shailendra, Antimisiaris, Sophia G., Chougule, Mahavir Bhupal, Shoyele, Sunday A., Alexander, Amit · 2018 · Journal of Controlled Release
- Amyloid β oligomers in Alzheimer’s disease pathogenesis, treatment, and diagnosisViola, Kirsten L., Klein, William L. · 2015 · Acta Neuropathologica
- Alzheimer's Disease: From Pathology to Therapeutic ApproachesJakob‐Roetne, Roland, Jacobsen, Helmut · 2009 · Angewandte Chemie International Edition
- Resistance to autosomal dominant Alzheimer’s disease in an APOE3 Christchurch homozygote: a case reportArboleda-Velasquez, Joseph F., Lopera, Francisco, O’Hare, Michael, Delgado-Tirado, Santiago, Marino, Claudia, Chmielewska, Natalia, Saez-Torres, Kahira L., Amarnani, Dhanesh, Schultz, Aaron P., Sperling, Reisa A. et al. · 2019 · Nature Medicine
- A multimodal RAGE-specific inhibitor reduces amyloid β–mediated brain disorder in a mouse model of Alzheimer diseaseDeane, Rashid, Singh, Itender, Sagare, Abhay P., Bell, Robert D., Ross, Nathan T., LaRue, Barbra, Love, Rachal, Perry, Sheldon, Paquette, Nicole, Deane, Richard J. et al. · 2012 · Journal of Clinical Investigation
- Effects of secreted oligomers of amyloid β‐protein on hippocampal synaptic plasticity: a potent role for trimersTownsend, Matthew, Shankar, Ganesh M., Mehta, Tapan, Walsh, Dominic M., Selkoe, Dennis J. · 2006 · The Journal of Physiology
- The redox chemistry of the Alzheimer's disease amyloid β peptideSmith, Danielle G., Cappai, Roberto, Barnham, Kevin J. · 2007 · Biochimica et Biophysica Acta (BBA) - Biomembranes
- What is the role of protein aggregation in neurodegeneration?Christopher A. Ross, Michelle A. Poirier · 2005 · Nature Reviews Molecular Cell Biology
- Astrocyte Senescence as a Component of Alzheimer’s DiseaseBhat, Rekha, Crowe, Elizabeth P., Bitto, Alessandro, Moh, Michelle, Katsetos, Christos D., Garcia, Fernando U., Johnson, Frederick Bradley, Trojanowski, John Q., Sell, Christian, Torres, Claudio · 2012 · PLoS ONE
- Amyloid oligomers: formation and toxicity of Aβ oligomersMasafumi Sakono, Tamotsu Zako · 2010 · FEBS Journal
- Suppression of glymphatic fluid transport in a mouse model of Alzheimer's diseasePeng, Weiguo, Achariyar, Thiyagarajan M., Li, Baoman, Liao, Yonghong, Mestre, Humberto, Hitomi, Emi, Regan, Sean, Kasper, Tristan, Peng, Sisi, Ding, Fengfei et al. · 2016 · Neurobiology of Disease
- Amyloidogenic Protein–Membrane Interactions: Mechanistic Insight from Model SystemsSara M. Butterfield, Hilal Ahmed Lashuel · 2010 · Angewandte Chemie International Edition
- Functional Alterations in Memory Networks in Early Alzheimer’s DiseaseReisa Anne Sperling, Bradford Clark Dickerson, Maija M. Pihlajamaki, Patrizia Vannini, Peter S. LaViolette, Ottavio V. Vitolo, Trey Hedden, John Alex Becker, Dorene M. Rentz, Dennis J. Selkoe et al. · 2010 · NeuroMolecular Medicine
- The road to restoring neural circuits for the treatment of Alzheimer's diseaseCanter, Rebecca G., Penney, Jay, Tsai, Li-Huei · 2016 · Nature
- Amyloid Fibrils as Building Blocks for Natural and Artificial Functional MaterialsTuomas P. J. Knowles, Raffaele Mezzenga · 2016 · Advanced Materials
- The Cell Biology of Synaptic PlasticityHo, Victoria M., Lee, Ji-Ann, Martin, Kelsey C. · 2011 · Science
- Amyloid beta oligomers induce impairment of neuronal insulin receptorsZhao, Wei‐Qin, De Felice, Fernanda G., Fernandez, Sara, Chen, Hui, Lambert, Mary P., Quon, Michael J., Krafft, Grant A., Klein, William L. · 2008 · The FASEB Journal
- Traumatic brain injury and amyloid-β pathology: a link to Alzheimer's disease?Johnson, Victoria E., Stewart, William, Smith, Douglas H. · 2010 · Nature Reviews Neuroscience
- Paradigm shifts in Alzheimer's disease and other neurodegenerative disorders: The emerging role of oligomeric assembliesMarina D. Kirkitadze, Gal Bitan, David B. Teplow · 2002 · Journal of Neuroscience Research
- Oligomeric Aβ-induced synaptic dysfunction in Alzheimer’s diseaseShichun Tu, Shu‐ichi Okamoto, Stuart A. Lipton, Huaxi Xu · 2014 · Molecular Neurodegeneration
- Inflammatory processes in Alzheimer's diseaseHeneka, Michael T., O'Banion, M. Kerry · 2007 · Journal of Neuroimmunology
- Common mechanisms of amyloid oligomer pathogenesis in degenerative diseaseGlabe, Charles G. · 2006 · Neurobiology of Aging
- The Formation of Highly Soluble Oligomers of α-Synuclein Is Regulated by Fatty Acids and Enhanced in Parkinson's DiseaseRonit Sharon, Ifat Bar-Joseph, Matthew P. Frosch, Dominic M. Walsh, James A. Hamilton, Dennis J. Selkoe · 2003 · Neuron
- Dendritic Spine Abnormalities in Amyloid Precursor Protein Transgenic Mice Demonstrated by Gene Transfer and Intravital Multiphoton MicroscopySpires, Tara L., Meyer-Luehmann, Melanie, Stern, Edward A., McLean, Pamela J., Skoch, Jesse, Nguyen, Paul T., Bacskai, Brian J., Hyman, Bradley T. · 2005 · The Journal of Neuroscience
- Globular amyloid β‐peptide
<sub>1−42</sub>
oligomer − a homogenous and stable neuropathological protein in Alzheimer's diseaseBarghorn, Stefan, Nimmrich, Volker, Striebinger, Andreas, Krantz, Carsten, Keller, Patrick, Janson, Bodo, Bahr, Michael, Schmidt, Martin, Bitner, Robert S., Harlan, John et al. · 2005 · Journal of Neurochemistry
- Protein Aggregation in the Brain: The Molecular Basis for Alzheimer’s and Parkinson’s DiseasesG. Brent Irvine, Omar M. A. El‐Agnaf, Ganesh M. Shankar, Dominic M. Walsh · 2008 · Molecular Medicine
- Evidence of fibril-like β-sheet structures in a neurotoxic amyloid intermediate of Alzheimer's β-amyloidSandra Chimon, Medhat A. Shaibat, Christopher R Jones, Diana C Calero, Buzulagu Aizezi, Yoshitaka Ishii · 2007 · Nature Structural & Molecular Biology
- Synaptic degeneration in Alzheimer's diseaseArendt, Thomas · 2009 · Acta Neuropathologica
- Insulin, insulin-degrading enzyme and amyloid-β peptide in Alzheimer's disease: review and hypothesisWei Qiao Qiu, Marshal F. Folstein · 2005 · Neurobiology of Aging
- Amyloid-Beta: A Crucial Factor in Alzheimer's DiseaseSaeed Sadigh‐Eteghad, Babak Sabermarouf, Alireza Majdi, Mahnaz Talebi, Mehdi Farhoudi, Javad Mahmoudi · 2014 · Medical Principles and Practice
- Amyloid β-peptide inhibition of the PKA/CREB pathway and long-term potentiation: Reversibility by drugs that enhance cAMP signalingVitolo, Ottavio V., Sant'Angelo, Antonino, Costanzo, Vincenzo, Battaglia, Fortunato, Arancio, Ottavio, Shelanski, Michael · 2002 · Proceedings of the National Academy of Sciences
- A Transgenic Alzheimer Rat with Plaques, Tau Pathology, Behavioral Impairment, Oligomeric Aβ, and Frank Neuronal LossRobert M. Cohen, Kavon P. Rezai-Zadeh, Tara M. Weitz, Altan Rentsendorj, David Gate, Inna E Spivak, Yasmin Bholat, Vitaly Vasilevko, Charles G. Glabe, Joshua J. Breunig et al. · 2013 · Journal of Neuroscience
- Reelin, lipoprotein receptors and synaptic plasticityHerz, Joachim, Chen, Ying · 2006 · Nature Reviews Neuroscience
- Neurotoxicity of Alzheimer’s disease Aβ peptides is induced by small changes in the Aβ42 to Aβ40 ratioKuperstein, Inna, Broersen, Kerensa, Benilova, Iryna, Rozenski, Jef, Jonckheere, Wim, Debulpaep, Maja, Vandersteen, Annelies, Segers‐Nolten, Ine, Van Der Werf, Kees, Subramaniam, Vinod et al. · 2010 · The EMBO Journal
- The Role of NMDA Receptors in Alzheimer’s DiseaseLiu, Jinping, Chang, Lirong, Song, Yizhi, Li, Hui, Wu, Yan · 2019 · Frontiers in Neuroscience
- The significance of the cholinergic system in the brain during aging and in Alzheimer’s diseaseReinhard Schliebs, Thomas Arendt · 2006 · Journal of Neural Transmission
- Alzheimer’s disease pathology propagation by exosomes containing toxic amyloid-beta oligomersSardar Sinha, Maitrayee, Ansell-Schultz, Anna, Civitelli, Livia, Hildesjö, Camilla, Larsson, Max, Lannfelt, Lars, Ingelsson, Martin, Hallbeck, Martin · 2018 · Acta Neuropathologica
- Detection of elevated levels of α-synuclein oligomers in CSF from patients with Parkinson diseaseTakahiko Tokuda, M.M. Qureshi, Mustafa Taleb Ardah, S. Varghese, Safa A. S. Shehab, Takashi Kasai, Noriko Ishigami, Akira Tamaoka, M. Nakagawa, Omar M. A. El‐Agnaf · 2010 · Neurology
- Prevention of Transthyretin Amyloid Disease by Changing Protein Misfolding EnergeticsPer Hammarström, R. Luke Wiseman, Evan T. Powers, Jeffery W. Kelly · 2003 · Science
- Solution NMR Studies of the Aβ(1−40) and Aβ(1−42) Peptides Establish that the Met35 Oxidation State Affects the Mechanism of Amyloid FormationLiming Hou, Haiyan Shao, Yongbo Zhang, Hua Long Li, N K Menon, Elizabeth B. Neuhaus, John M. Brewer, In‐Ja L. Byeon, Dale G. Ray, Michael Peter Vitek et al. · 2004 · Journal of the American Chemical Society
- Oxidative DNA damage in mild cognitive impairment and late-stage Alzheimer's diseaseLovell, M. A., Markesbery, W. R. · 2007 · Nucleic Acids Research
- Alzheimer's disease: synaptic dysfunction and AβGanesh M. Shankar, Dominic M. Walsh · 2009 · Molecular Neurodegeneration
- Localized Surface Plasmon Resonance BiosensorsJing Zhao, Xiaoyu Zhang, Chanda Ranjit Yonzon, Amanda J. Haes, Richard P. Van Duyne · 2006 · Nanomedicine
- Synaptic degeneration in Alzheimer diseaseTzioras, Makis, McGeachan, Robert I., Durrant, Claire S., Spires-Jones, Tara L. · 2023 · Nature Reviews Neurology
- Alzheimer's disease, β‐amyloid, glutamate, NMDA receptors and memantine – searching for the connectionsDanysz, Wojciech, Parsons, Chris G · 2012 · British Journal of Pharmacology
- Spherical aggregates of β-amyloid (amylospheroid) show high neurotoxicity and activate tau protein kinase I/glycogen synthase kinase-3βMinako M. Hoshi, Michio Sato, Shinichiro Matsumoto, Akihiko Noguchi, Kaori Yasutake, Natsuko Yoshida, Kazuki Sato · 2003 · Proceedings of the National Academy of Sciences
- Antiparallel β-sheet: a signature structure of the oligomeric amyloid β-peptideEmilie Cerf, Rabia Sarroukh, Shiori Tamamizu‐Kato, Leonid Breydo, Sylvie Derclaye, Yves F. Dufrêne, Vasanthy Narayanaswami, Erik Goormaghtigh, Jean‐Marie Ruysschaert, Vincent Raussens · 2009 · Biochemical Journal
- Different Conformations of Amyloid β Induce Neurotoxicity by Distinct Mechanisms in Human Cortical NeuronsAtul M. Deshpande, Erene W. Mina, Charles G. Glabe, Jorge A. Busciglio · 2006 · Journal of Neuroscience
- Amyloid β protein immunotherapy neutralizes Aβ oligomers that disrupt synaptic plasticity in vivoKlyubin, Igor, Walsh, Dominic M, Lemere, Cynthia A, Cullen, William K, Shankar, Ganesh M, Betts, Vicki, Spooner, Edward T, Jiang, Liying, Anwyl, Roger, Selkoe, Dennis J et al. · 2005 · Nature Medicine
- Accumulation of Pathological Tau Species and Memory Loss in a Conditional Model of TauopathyZdenek Berger, Hanno M. Roder, Amanda Hanna, Aaron M. Carlson, Vijayaraghavan Rangachari, Mei Yue, Zbigniew K. Wszołek, Karen H. Ashe, Joshua A. Knight, Dennis W. Dickson et al. · 2007 · Journal of Neuroscience
- Modulation of the endoplasmic reticulum–mitochondria interface in Alzheimer’s disease and related modelsHedskog, Louise, Pinho, Catarina Moreira, Filadi, Riccardo, Rönnbäck, Annica, Hertwig, Laura, Wiehager, Birgitta, Larssen, Pia, Gellhaar, Sandra, Sandebring, Anna, Westerlund, Marie et al. · 2013 · Proceedings of the National Academy of Sciences
- Small assemblies of unmodified amyloid $beta;-protein are the proximate neurotoxin in Alzheimer?s diseaseWilliam L. Klein, W. Blaine Stine, David B. Teplow · 2004 · Neurobiology of Aging
- Dissecting the pathological effects of human Aβ40 and Aβ42 in Drosophila : A potential model for Alzheimer's diseaseKoichi Iijima, Hsin‐Ping Liu, Ann‐Shyn Chiang, Stephen Hearn, Mary Konsolaki, Yi Zhong · 2004 · Proceedings of the National Academy of Sciences
- From Macroscopic Measurements to Microscopic Mechanisms of Protein AggregationSamuel I. A. Cohen, Michele Vendruscolo, Christopher Martin Dobson, Tuomas P. J. Knowles · 2012 · Journal of Molecular Biology
- A Hundred Years of Alzheimer's Disease ResearchHardy, John · 2006 · Neuron
- Secondary nucleation in amyloid formationMattias Törnquist, Thomas C. T. Michaels, Kalyani Sanagavarapu, Xiaoting Yang, Georg Meisl, Samuel I. A. Cohen, Tuomas P. J. Knowles, Sara Snogerup Linse · 2018 · Chemical Communications
- Deleterious Effects of Amyloid β Oligomers Acting as an Extracellular Scaffold for mGluR5Renner, Marianne, Lacor, Pascale N., Velasco, Pauline T., Xu, Jian, Contractor, Anis, Klein, William L., Triller, Antoine · 2010 · Neuron
- Antiamyloidogenic and neuroprotective functions of cathepsin B: implications for Alzheimer's disease.Sarah Mueller-Steiner, Yun-Gui Zhou, H. Arai, E. Roberson, Bing-Gui Sun, Jennifer Chen, Xin Wang, Gui-Qiu Yu, Luke Esposito, L. Mucke et al. · 2006 · Neuron
- BACE1 Deficiency Rescues Memory Deficits and Cholinergic Dysfunction in a Mouse Model of Alzheimer's DiseaseOhno, Masuo, Sametsky, Evgeny A, Younkin, Linda H, Oakley, Holly, Younkin, Steven G, Citron, Martin, Vassar, Robert, Disterhoft, John F · 2004 · Neuron
- BACE1, a Major Determinant of Selective Vulnerability of the Brain to Amyloid-β Amyloidogenesis, is Essential for Cognitive, Emotional, and Synaptic FunctionsLaird, Fiona M., Cai, Huaibin, Savonenko, Alena V., Farah, Mohamed H., He, Kaiwen, Melnikova, Tatyana, Wen, Hongjin, Chiang, Hsueh-Cheng, Xu, Guilian, Koliatsos, Vassilis E. et al. · 2005 · The Journal of Neuroscience
- Synapses and Alzheimer's DiseaseSheng, M., Sabatini, B. L., Sudhof, T. C. · 2012 · Cold Spring Harbor Perspectives in Biology
- The physiological roles of tau and Aβ: implications for Alzheimer’s disease pathology and therapeuticsKent, Sarah A., Spires-Jones, Tara L., Durrant, Claire S. · 2020 · Acta Neuropathologica
- Brain Insulin Resistance and Deficiency as Therapeutic Targets in Alzheimers DiseaseSuzanne M. de la Monte · 2012 · Current Alzheimer Research
- Role of toll-like receptor signalling in A uptake and clearanceTahara, K., Kim, H.-D., Jin, J.-J., Maxwell, J. A., Li, L., Fukuchi, K.-i. · 2006 · Brain
- Amyloid toxicity in Alzheimer’s diseaseReiss, Allison B., Arain, Hirra A., Stecker, Mark M., Siegart, Nicolle M., Kasselman, Lora J. · 2018 · Reviews in the Neurosciences
- Small-molecule conversion of toxic oligomers to nontoxic β-sheet–rich amyloid fibrilsJan Bieschke, Martin Herbst, Thomas Wiglenda, Ralf P. Friedrich, Annett Boeddrich, Franziska Schiele, Daniela Kleckers, Juan Miguel López del Amo, Björn Andreas Grüning, Qinwen Wang et al. · 2011 · Nature Chemical Biology
- Amyloid Polymorphism: Structural Basis and Neurobiological RelevanceRobert Tycko · 2015 · Neuron
- Recent advances in the multitarget‐directed ligands approach for the treatment of Alzheimer's diseaseRafael M. Leon, Antonio G. Garcı́a, Jose Luis Marco · 2011 · Medicinal Research Reviews
- Alzheimer disease models and human neuropathology: similarities and differencesCharles J. Duyckaerts, Marie‐Claude Potier, Benoı̂t Delatour · 2007 · Acta Neuropathologica
- The Aβ oligomer hypothesis for synapse failure and memory loss in Alzheimer’s diseaseFerreira, Sergio T., Klein, William L. · 2011 · Neurobiology of Learning and Memory
- The α‐to‐β Conformational Transition of Alzheimer's Aβ‐(1–42) Peptide in Aqueous Media is Reversible: A Step by Step Conformational Analysis Suggests the Location of β Conformation SeedingSimona Tomaselli, Veronica Esposito, Paolo Vangone, Nico A. J. van Nuland, Alexandre M. J. J. Bonvin, Remo Guerrini, Teodorico Tancredi, Piero Andrea Temussi, Delia Picone · 2006 · ChemBioChem
- Block of Long-Term Potentiation by Naturally Secreted and Synthetic Amyloid β-Peptide in Hippocampal Slices Is Mediated via Activation of the Kinases c-Jun N-Terminal Kinase, Cyclin-Dependent Kinase 5, and p38 Mitogen-Activated Protein Kinase as well as Metabotropic Glutamate Receptor Type 5Wang, Qinwen, Walsh, Dominic M., Rowan, Michael J., Selkoe, Dennis J., Anwyl, Roger · 2004 · The Journal of Neuroscience
- Persistent improvement in synaptic and cognitive functions in an Alzheimer mouse model after rolipram treatmentGong, Bing, Vitolo, Ottavio V., Trinchese, Fabrizio, Liu, Shumin, Shelanski, Michael, Arancio, Ottavio · 2004 · Journal of Clinical Investigation
- Neuroinflammatory processes in Alzheimer’s diseaseHeneka, Michael T., O’Banion, M. Kerry, Terwel, Dick, Kummer, Markus Peter · 2010 · Journal of Neural Transmission
- Alzheimer's disease-type neuronal tau hyperphosphorylation induced by Aβ oligomersDe Felice, Fernanda G., Wu, Diana, Lambert, Mary P., Fernandez, Sara J., Velasco, Pauline T., Lacor, Pascale N., Bigio, Eileen H., Jerecic, Jasna, Acton, Paul J., Shughrue, Paul J. et al. · 2008 · Neurobiology of Aging
- Reversing EphB2 depletion rescues cognitive functions in Alzheimer modelCissé, Moustapha, Halabisky, Brian, Harris, Julie, Devidze, Nino, Dubal, Dena B., Sun, Binggui, Orr, Anna, Lotz, Gregor, Kim, Daniel H., Hamto, Patricia et al. · 2011 · Nature
- Alzheimer's disease, normal-pressure hydrocephalus, and senescent changes in CSF circulatory physiology: a hypothesis.G. Silverberg, M. Mayo, Thomas Saul, E. Rubenstein, D. Mcguire · 2003 · Lancet Neurology
- Strategies for disease modification in Alzheimer's diseaseMartin Citron · 2004 · Nature reviews. Neuroscience
- Targeting BACE1 with siRNAs ameliorates Alzheimer disease neuropathology in a transgenic modelOded Singer, Robert A. Marr, Edward M. Rockenstein, Leslie A. Crews, Nicole G. Coufal, Fred H. Gage, Inder M. Verma, Eliezer Masliah · 2005 · Nature Neuroscience
- Amyloid seeds formed by cellular uptake, concentration, and aggregation of the amyloid-beta peptideHu, Xiaoyan, Crick, Scott L., Bu, Guojun, Frieden, Carl, Pappu, Rohit V., Lee, Jin-Moo · 2009 · Proceedings of the National Academy of Sciences
- Redox‐Active Metals, Oxidative Stress, and Alzheimer's Disease PathologyHUANG, XUDONG, MOIR, ROBERT D., TANZI, RUDOLPH E., BUSH, ASHLEY I., ROGERS, JACK T. · 2004 · Annals of the New York Academy of Sciences
- Ubiquitin Hydrolase Uch-L1 Rescues β-Amyloid-Induced Decreases in Synaptic Function and Contextual MemoryBing Gong, Zixuan Cao, Ping Zheng, Ottavio V. Vitolo, Shumin Liu, Agnieszka Staniszewski, Donna L. Moolman, Hong Zhang, Michael L. Shelanski, Ottavio Arancio · 2006 · Cell
- Protein aggregation in crowded environmentsR. John Ellis, Allen P. Minton · 2006 · Biological Chemistry
- β-Amyloid Monomers Are NeuroprotectiveGiuffrida, Maria Laura, Caraci, Filippo, Pignataro, Bruno, Cataldo, Sebastiano, De Bona, Paolo, Bruno, Valeria, Molinaro, Gemma, Pappalardo, Giuseppe, Messina, Angela, Palmigiano, Angelo et al. · 2009 · The Journal of Neuroscience
- A new amyloid β variant favoring oligomerization in Alzheimer's‐type dementiaTakami Tomiyama, Tetsu Nagata, Hiroyuki Shimada, Rie Teraoka, Akiko Fukushima, Hyoue Kanemitsu, Hiroshi Takuma, Ryozo Kuwano, Masaki Imagawa, Suzuka Ataka et al. · 2008 · Annals of Neurology
- Memory Impairment in Transgenic Alzheimer Mice Requires Cellular Prion ProteinGimbel, David A., Nygaard, Haakon B., Coffey, Erin E., Gunther, Erik C., Laurén, Juha, Gimbel, Zachary A., Strittmatter, Stephen M. · 2010 · The Journal of Neuroscience
- Brain Energy and Oxygen Metabolism: Emerging Role in Normal Function and DiseaseMichelle Evelyn Watts, Roger Pocock, Charles Claudianos · 2018 · Frontiers in Molecular Neuroscience
- A Recessive Mutation in the APP Gene with Dominant-Negative Effect on AmyloidogenesisGiuseppe Di Fede, Marcella Catania, Michela Morbin, Giacomina Rossi, Silvia Suardi, Giulia Mazzoleni, Marco Merlin, Anna Rıta Gıovagnolı, Sara Prioni, Alessandra Erbetta et al. · 2009 · Science