Naturally secreted oligomers of amyloid β protein potently inhibit hippocampal long-term potentiation in vivo

Walsh, Dominic M., Klyubin, Igor, Fadeeva, Julia V., Cullen, William K., Anwyl, Roger, Wolfe, Michael S., Rowan, Michael J., Selkoe, Dennis J.·2002·Nature

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  13. Protein aggregation, metals and oxidative stress in neurodegenerative diseases
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  14. Activation of the c-Jun N-terminal Kinase Signaling Cascade Mediates the Effect of Amyloid-β on Long Term Potentiation and Cell Death in Hippocampus
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  15. The keystone of Alzheimer pathogenesis might be sought in Aβ physiology
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  16. Folding events in the 21-30 region of amyloid β-protein (Aβ) studied in silico
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  17. The amyloid-cell membrane system. The interplay between the biophysical features of oligomers/fibrils and cell membrane defines amyloid toxicity
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  18. Protofibril Formation of Amyloid β-Protein at Low pH via a Non-cooperative Elongation Mechanism
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