Naturally secreted oligomers of amyloid β protein potently inhibit hippocampal long-term potentiation in vivo

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2. A molecular chaperone breaks the catalytic cycle that generates toxic Aβ oligomers
   Samuel I. A. Cohen, Paolo Arosio, Jenny Presto, Firoz Roshan Kurudenkandy, Henrik Biverstål, Lisa Dolfe, Christopher J.R. Dunning, Xiaoting Yang, Birgitta Frohm, Michele Vendruscolo et al. · 2015 · Nature Structural & Molecular Biology
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4. Stabilization of a β-hairpin in monomeric Alzheimer's amyloid-β peptide inhibits amyloid formation
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5. Calcium Signaling and Amyloid Toxicity in Alzheimer Disease
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7. Metal ions and amyloid fiber formation in neurodegenerative diseases. Copper, zinc and iron in Alzheimer's, Parkinson's and prion diseases
   John H. Viles · 2012 · Coordination Chemistry Reviews
8. Are amyloid diseases caused by protein aggregates that mimic bacterial pore-forming toxins?
   Hilal Ahmed Lashuel, Peter T. Lansbury · 2006 · Quarterly Reviews of Biophysics
9. The two faces of protein misfolding: gain‐ and loss‐of‐function in neurodegenerative diseases
   Konstanze F. Winklhofer, Jörg Tatzelt, Christian Haass · 2008 · The EMBO Journal
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    Almeida, Claudia G., Tampellini, Davide, Takahashi, Reisuke H., Greengard, Paul, Lin, Michael T., Snyder, Eric M., Gouras, Gunnar K. · 2005 · Neurobiology of Disease
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    Cirrito, John R., May, Patrick C., O'Dell, Mark A., Taylor, Jennie W., Parsadanian, Maia, Cramer, Jeffrey W., Audia, James E., Nissen, Jeffrey S., Bales, Kelly R., Paul, Steven M. et al. · 2003 · The Journal of Neuroscience
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    Jay, Taylor R., von Saucken, Victoria E., Landreth, Gary E. · 2017 · Molecular Neurodegeneration
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    Megan M. Varnum, Tsuneya Ikezu · 2012 · Archivum Immunologiae et Therapiae Experimentalis
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    Walker, Keenan A., Power, Melinda C., Gottesman, Rebecca F. · 2017 · Current Hypertension Reports
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    Robert A. Marr, Edward M. Rockenstein, Atish Mukherjee, Mark S. Kindy, Louis B. Hersh, Fred H. Gage, Inder M. Verma, Eliezer Masliah · 2003 · Journal of Neuroscience
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    Tseng, Bertrand P., Green, Kim N., Chan, Julie L., Blurton-Jones, Mathew, LaFerla, Frank M. · 2008 · Neurobiology of Aging
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    Chen, Bonan, Yu, Peiyao, Chan, Wai Nok, Xie, Fuda, Zhang, Yigan, Liang, Li, Leung, Kam Tong, Lo, Kwok Wai, Yu, Jun, Tse, Gary M. K. et al. · 2024 · Signal Transduction and Targeted Therapy
19. Calcium hypothesis of Alzheimer’s disease
    Michael John Berridge · 2009 · Pflügers Archiv - European Journal of Physiology
20. The Exosome Secretory Pathway Transports Amyloid Precursor Protein Carboxyl-terminal Fragments from the Cell into the Brain Extracellular Space
    Rocío Pérez‐González, Sébastien A. Gauthier, Asok R. Kumar, Efrat Levy · 2012 · Journal of Biological Chemistry
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    Selkoe, Dennis J. · 2004 · Annals of Internal Medicine
22. Synaptopathies: synaptic dysfunction in neurological disorders – A review from students to students
    Lepeta, Katarzyna, Lourenco, Mychael V., Schweitzer, Barbara C., Martino Adami, Pamela V., Banerjee, Priyanjalee, Catuara‐Solarz, Silvina, de La Fuente Revenga, Mario, Guillem, Alain Marc, Haidar, Mouna, Ijomone, Omamuyovwi M. et al. · 2016 · Journal of Neurochemistry
23. Heat Shock Proteins 70 and 90 Inhibit Early Stages of Amyloid β-(1–42) Aggregation in Vitro
    Christopher G. Evans, Susanne Wisén, Jason E. Gestwicki · 2006 · Journal of Biological Chemistry
24. Differences between amyloid-β aggregation in solution and on the membrane: insights into elucidation of the mechanistic details of Alzheimer's disease
    Samuel A. Kotler, P.J. Walsh, Jeffrey Brender, Ayyalusamy Ramamoorthy · 2014 · Chemical Society Reviews
25. Insulin and Insulin Resistance in Alzheimer’s Disease
    Aleksandra Sędzikowska, Leszek Szablewski · 2021 · International Journal of Molecular Sciences
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    Oddo, Salvatore, Caccamo, Antonella, Tran, Levina, Lambert, Mary P., Glabe, Charles G., Klein, William L., LaFerla, Frank M. · 2006 · Journal of Biological Chemistry
27. Amyloid-β and tau complexity — towards improved biomarkers and targeted therapies
    Juan Carlos Polanco, Chuanzhou Li, Liviu‐Gabriel Bodea, Ramón Martínez‐Mármol, Frédéric A. Meunier, Jürgen Götz · 2017 · Nature Reviews Neurology
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    Rachel E. Lackie, Andrzej Maciejewski, Valeriy G. Ostapchenko, José Marques-Lopes, Wing‐Yiu Choy, Martin L. Duennwald, Vânia F. Prado, Marco A. M. Prado · 2017 · Frontiers in Neuroscience
29. Soluble amyloid-β oligomers as synaptotoxins leading to cognitive impairment in Alzheimer’s disease
    Ferreira, Sergio T., Lourenco, Mychael V., Oliveira, Mauricio M., De Felice, Fernanda G. · 2015 · Frontiers in Cellular Neuroscience
30. Progressive age‐related development of Alzheimer‐like pathology in APP/PS1 mice
    Fabrizio Trinchese, Shumin Liu, Fortunato Battaglia, Sean Walter, Paul M. Mathews, Ottavio Arancio · 2004 · Annals of Neurology
31. Peptides Containing β-Amino Acid Patterns: Challenges and Successes in Medicinal Chemistry
    Chiara Cabrele, Tamás A. Martinek, Oliver Reiser, Łukasz Berlicki · 2014 · Journal of Medicinal Chemistry
32. Intraneuronal β-amyloid accumulation and synapse pathology in Alzheimer’s disease
    Gouras, Gunnar K., Tampellini, Davide, Takahashi, Reisuke H., Capetillo-Zarate, Estibaliz · 2010 · Acta Neuropathologica
33. Oxidative stress precedes fibrillar deposition of Alzheimer's disease amyloid β-peptide (1–42) in a transgenic Caenorhabditis elegans model
    Drake, J · 2003 · Neurobiology of Aging
34. Prefibrillar Amyloid Protein Aggregates Share Common Features of Cytotoxicity
    Monica Bucciantini, Giulia Calloni, Fabrizio Chiti, Lucia Formigli, Daniele Nosi, Christopher Martin Dobson, Massimo Stefani · 2004 · Journal of Biological Chemistry
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    Wei, Wei, Nguyen, Louis N, Kessels, Helmut W, Hagiwara, Hiroaki, Sisodia, Sangram, Malinow, Roberto · 2010 · Nature Neuroscience
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    Michelle A. Poirier, Huilin Li, Jed C. Macosko, Shuowei Cai, L. Mario Amzel, Christopher A. Ross · 2002 · Journal of Biological Chemistry
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    Yufeng Yang, Isao Nishimura, Yuzuru Imai, Ryōsuke Takahashi, Bingwei Lu · 2003 · Neuron
39. Probing the biology of Alzheimer’s disease in mice
    Ashe, Karen H., Zahs, Kathleen R. · 2010 · Neuron
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    Hampel, Harald, Caraci, Filippo, Cuello, A. Claudio, Caruso, Giuseppe, Nisticò, Robert, Corbo, Massimo, Baldacci, Filippo, Toschi, Nicola, Garaci, Francesco, Chiesa, Patrizia A. et al. · 2020 · Frontiers in Immunology
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    Akter, Kawser, Lanza, Emily A., Martin, Stephen A., Myronyuk, Natalie, Rua, Melanie, Raffa, Robert B. · 2011 · British Journal of Clinical Pharmacology
42. Soluble Aβ oligomer production and toxicity
    Larson, Megan E., Lesné, Sylvain E. · 2012 · Journal of Neurochemistry
43. Metals and amyloid‐β in Alzheimer's disease
    Christa J. Maynard, Ashley Ian Bush, Colin Louis Masters, Roberto Cappai, Qiao‐Xin Li · 2005 · International Journal of Experimental Pathology
44. Calcium signaling in neurodegeneration
    Philippe Marambaud, Ute Dreses‐Werringloer, Valérie Vingtdeux · 2009 · Molecular Neurodegeneration
45. Neurodegenerative disease and adult neurogenesis
    Winner, Beate, Kohl, Zacharias, Gage, Fred H. · 2011 · European Journal of Neuroscience
46. Intraneuronal Aβ, non-amyloid aggregates and neurodegeneration in a Drosophila model of Alzheimer’s disease
    Damian C. Crowther, Kerri J. Kinghorn, Elena Miranda, Richard Page, J.A. Curry, Fiona Duthie, David Gubb, David A. Lomas · 2005 · Neuroscience
47. Inducible Expression of Tau Repeat Domain in Cell Models of Tauopathy
    Inna Khlistunova, Jacek Biernat, Yipeng Wang, Marcus Pickhardt, Martin von Bergen�, Zuzana Gažová, Eckhard Mandelkow�, Eva‐Maria Mandelkow · 2005 · Journal of Biological Chemistry
48. Loss‐of‐function presenilin mutations in Alzheimer disease
    Bart De Strooper · 2007 · EMBO Reports
49. Functions and dysfunctions of nitric oxide in brain
    Pol Picón-Pagès, Joan Garcia-Buendia, Francisco J. Muñoz · 2018 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
50. A modified β‐amyloid hypothesis: intraneuronal accumulation of the β‐amyloid peptide – the first step of a fatal cascade
    Oliver Wirths, Gerd Multhaup, Thomas A. Bayer · 2004 · Journal of Neurochemistry
51. The Zyggregator method for predicting protein aggregation propensities
    Gian Gaetano Tartaglia, Michele Vendruscolo · 2008 · Chemical Society Reviews
52. Amyloid-β Aggregation
    Verena H. Finder, Rudi Glockshuber · 2007 · Neurodegenerative Diseases
53. Anisotropic Black Phosphorus Synaptic Device for Neuromorphic Applications
    He Tian, Qiushi Guo, Yujun Xie, Huan Zhao, Li Cheng, Judy J. Cha, Fengnian Xia, Han Wang · 2016 · Advanced Materials
54. Tau-targeting antisense oligonucleotide MAPTRx in mild Alzheimer’s disease: a phase 1b, randomized, placebo-controlled trial
    Mummery, Catherine J., Börjesson-Hanson, Anne, Blackburn, Daniel J., Vijverberg, Everard G. B., De Deyn, Peter Paul, Ducharme, Simon, Jonsson, Michael, Schneider, Anja, Rinne, Juha O., Ludolph, Albert C. et al. · 2023 · Nature Medicine
55. The crucial role of metal ions in neurodegeneration: the basis for a promising therapeutic strategy
    Gaeta, Alessandra, Hider, Robert C · 2005 · British Journal of Pharmacology
56. Transmissible spongiform encephalopathies
    Steven John Collins, Victoria Lawson, Colin Louis Masters · 2004 · The Lancet
57. Biochemical and medical aspects of the indoleamine 2,3-dioxygenase-initiated l-tryptophan metabolism
    Osamu Takikawa · 2005 · Biochemical and Biophysical Research Communications
58. Amyloidogenic light chains induce cardiomyocyte contractile dysfunction and apoptosis via a non-canonical p38α MAPK pathway
    Jianru Shi, Jian Guan, Bingbing Jiang, Daniel A. Brenner, Federica del Monte, Jennifer Ellis Ward, Lawreen Heller Connors, Douglas B. Sawyer, Marc J. Semigran, Thomas E. MacGillivray et al. · 2010 · Proceedings of the National Academy of Sciences
59. Clearing amyloid through the blood-brain barrier
    Zlokovic, Berislav V. · 2004 · Journal of Neurochemistry
60. Drug development for CNS disorders: strategies for balancing risk and reducing attrition
    Menelas N. Pangalos, Lee E. Schechter, Orest Hurko · 2007 · Nature Reviews Drug Discovery
61. Soluble protein oligomers as emerging toxins in Alzheimer’s and other amyloid diseases
    Ferreira, Sergio T., Vieira, Marcelo N. N., De Felice, Fernanda G. · 2007 · IUBMB Life
62. Valsartan lowers brain β-amyloid protein levels and improves spatial learning in a mouse model of Alzheimer disease
    Jun Wang, Lap Ho, Linghong Chen, Zhong Zhao, Wei Zhao, Xianjuan Qian, Nelson Humala, Ilana Seror, Sadie R. Bartholomew, Clive Rosendorff et al. · 2007 · Journal of Clinical Investigation
63. In silico study of amyloid β-protein folding and oligomerization
    Brigita Urbanc, Luis Cruz, Sijung Yun, Sergey V. Buldyrev, Gal Bitan, David B. Teplow, Eugene Stanley · 2004 · Proceedings of the National Academy of Sciences
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    Noel D. Lazo, Marianne A. Grant, Margaret M. Condron, Alan C. Rigby, David B. Teplow · 2005 · Protein Science
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    Agrawal, Mukta, Ajazuddin, Tripathi, Dulal K., Saraf, Swarnlata, Saraf, Shailendra, Antimisiaris, Sophia G., Mourtas, Spyridon, Hammarlund-Udenaes, Margareta, Alexander, Amit · 2017 · Journal of Controlled Release
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    Alan Ruttenberg, Tim Clark, William Bug, Matthias Samwald, Olivier Bodenreider, Helen Chen, Donald W. Doherty, Kerstin Forsberg, Yong Chao Gao, Vipul Kashyap et al. · 2007 · BMC Bioinformatics
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    Xiaojuan Sun, Weidong Chen, Yan‐Dong Wang · 2015 · Frontiers in Pharmacology
71. Emerging Principles of Conformation-Based Prion Inheritance
    Peter Chien, Jonathan S. Weissman, Angela H. DePace · 2003 · Annual Review of Biochemistry
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73. Inflammation and Alzheimer’s disease
    Lee, Young-Jung, Han, Sang Bae, Nam, Sang-Yoon, Oh, Ki-Wan, Hong, Jin Tae · 2010 · Archives of Pharmacal Research
74. Fyn inhibition rescues established memory and synapse loss in Alzheimer mice
    Kaufman, Adam C., Salazar, Santiago V., Haas, Laura T., Yang, Jinhee, Kostylev, Mikhail A., Jeng, Amanda T., Robinson, Sophie A., Gunther, Erik C., van Dyck, Christopher H., Nygaard, Haakon B. et al. · 2015 · Annals of Neurology
75. The role of amyloid β peptide 42 in Alzheimer's disease
    Mark A. Findeis · 2007 · Pharmacology & Therapeutics
76. Negatively Charged Gold Nanoparticles Inhibit Alzheimer's Amyloid‐β Fibrillization, Induce Fibril Dissociation, and Mitigate Neurotoxicity
    Yi‐Hung Liao, Yu‐Jen Chang, Yuji Yoshiike, Y. C. Chang, Yun‐Ru Chen · 2012 · Small
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    Jong Kil Lee, Nam‐Jung Kim · 2017 · Molecules
79. Endogenous amyloid‐β is necessary for hippocampal synaptic plasticity and memory
    Puzzo, Daniela, Privitera, Lucia, Fa', Mauro, Staniszewski, Agnieszka, Hashimoto, Gakuji, Aziz, Fahad, Sakurai, Mikako, Ribe, Elena M., Troy, Carol M., Mercken, Marc et al. · 2011 · Annals of Neurology
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    Adam Armada‐Moreira, Joana I. Gomes, Carolina Campos Pina, Oksana K. Savchak, Joana Gonçalves‐Ribeiro, Nádia Rei, Sara Pinto, Tatiana P. Morais, Robertta Silva Martins, Filipa F. Ribeiro et al. · 2020 · Frontiers in Cellular Neuroscience
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    Shipton, Olivia A., Leitz, Julie R., Dworzak, Jenny, Acton, Christine E. J., Tunbridge, Elizabeth M., Denk, Franziska, Dawson, Hana N., Vitek, Michael P., Wade-Martins, Richard, Paulsen, Ole et al. · 2011 · The Journal of Neuroscience
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    Adolfsson, O., Pihlgren, M., Toni, N., Varisco, Y., Buccarello, A. L., Antoniello, K., Lohmann, S., Piorkowska, K., Gafner, V., Atwal, J. K. et al. · 2012 · Journal of Neuroscience
83. Microtubule-associated protein tau is essential for long-term depression in the hippocampus
    Kimura, Tetsuya, Whitcomb, Daniel J., Jo, Jihoon, Regan, Philip, Piers, Thomas, Heo, Seonghoo, Brown, Christopher, Hashikawa, Tsutomu, Murayama, Miyuki, Seok, Heon et al. · 2014 · Philosophical Transactions of the Royal Society B: Biological Sciences
84. Emerging ideas on the molecular basis of protein and peptide aggregation
    Dave Thirumalai · 2003 · Current Opinion in Structural Biology
85. Type 3 diabetes is sporadic Alzheimer׳s disease: Mini-review
    Suzanne M. de la Monte · 2014 · European Neuropsychopharmacology
86. The role of CREB signaling in Alzheimer’s disease and other cognitive disorders
    Saura, Carlos A., Valero, Jorge · 2011 · revneuro
87. Lipids revert inert Aβ amyloid fibrils to neurotoxic protofibrils that affect learning in mice
    Ivo Cristiano Martins, Inna Kuperstein, Hannah Roslyne Wilkinson, Elke Maes, Mieke Vanbrabant, Wim Jonckheere, Patrick Van Gelder, Dieter Hartmann, Rudi D’Hooge, Bart De Strooper et al. · 2007 · The EMBO Journal
88. Neuroprotective, Anti-Amyloidogenic and Neurotrophic Effects of Apigenin in an Alzheimer’s Disease Mouse Model
    Le Zhao, Junli Wang, Rui Liu, Xiaoxu Li, Jianfei Li, Lu Zhang · 2013 · Molecules
89. Sensitive ELISA detection of amyloid‐β protofibrils in biological samples
    Englund, Hillevi, Sehlin, Dag, Johansson, Ann‐Sofi, Nilsson, Lars N. G., Gellerfors, Pär, Paulie, Staffan, Lannfelt, Lars, Pettersson, Frida Ekholm · 2007 · Journal of Neurochemistry
90. Alzheimer's disease: synapses gone cold
    Robert M. Koffie, Bradley T. Hyman, Tara L. Spires‐Jones · 2011 · Molecular Neurodegeneration
91. Circulating amyloidogenic free light chains and serum N-terminal natriuretic peptide type B decrease simultaneously in association with improvement of survival in AL
    Giovanni O. Palladini, Francesca Lavatelli, Paola Russo, Stefano Perlini, Vittorio Perfetti, Tiziana Bosoni, Laura Piera Obici, Arthur R. Bradwell, Gianvico Melzi d’Eril, Roberto Fogari et al. · 2006 · Blood
92. Aβ1-42 inhibition of LTP is mediated by a signaling pathway involving caspase-3, Akt1 and GSK-3β
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93. Protein Misfolding, Amyloid Formation, and Neurodegeneration
    Paul J. Muchowski · 2002 · Neuron
94. Amyloid‐beta oligomerization in Alzheimer dementia versus high‐pathology controls
    Thomas J. Esparza, Hanzhi Zhao, John R. Cirrito, Nigel J. Cairns, Randall John Bateman, David M. Holtzman, David L. Brody · 2012 · Annals of Neurology
95. Synaptic changes in Alzheimer’s disease and its models
    Julio Pozueta, Roger Lefort, Michael L. Shelanski · 2012 · Neuroscience
96. Targeting soluble Aβ peptide with Tramiprosate for the treatment of brain amyloidosis
    Francine Gervais, Julie Paquette, Céline Morissette, Pascale Krzywkowski, Mathilde W. N. Yu, Mounia Azzi, Diane Lacombe, Xianqi Kong, Ahmed M. Aman, Julie Laurin et al. · 2006 · Neurobiology of Aging
97. Tonic inhibition in dentate gyrus impairs long-term potentiation and memory in an Alzheimer’s disease model
    Wu, Zheng, Guo, Ziyuan, Gearing, Marla, Chen, Gong · 2014 · Nature Communications
98. Astrogliosis: An integral player in the pathogenesis of Alzheimer's disease
    Osborn, Lana M., Kamphuis, Willem, Wadman, Wytse J., Hol, Elly M. · 2016 · Progress in Neurobiology
99. Beta amyloid oligomers and fibrils stimulate differential activation of primary microglia
    Sondag, Cindy M, Dhawan, Gunjan, Combs, Colin K · 2009 · Journal of Neuroinflammation
100. Dysregulation of Histone Acetylation in the APP/PS1 Mouse Model of Alzheimer's Disease
     Yitshak I. Francis, Mauro Fà, Haider Ashraf, Hong Zhang, Agnieszka Staniszewski, David S. Latchman, Ottavio Arancio · 2009 · Journal of Alzheimer s Disease