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Autosomal recessive lissencephaly with cerebellar hypoplasia is associated with human RELN mutations
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Cites
A protein related to extracellular matrix proteins deleted in the mouse mutant reeler
D'Arcangelo, G., G. Miao, G., Chen, S.-C., Scares, H. D., Morgan, J. I., & Curran, T. (1995) · Nature · doi:10.1038/374719a0 · Cited by 1,748
Hiesberger, T., Trommsdorff, M., Howell, B. W., Goffinet, A., Mumby, M. C., Cooper, J. A., & Herz, J. (1999) · Neuron · doi:10.1016/s0896-6273(00)80861-2 · Cited by 916
Reelin Is a Ligand for Lipoprotein Receptors
D'Arcangelo, G., Homayouni, R., Keshvara, L., Rice, D. S., Sheldon, M., & Curran, T. (1999) · Neuron · doi:10.1016/s0896-6273(00)80860-0 · Cited by 808 · cited 1×
“that acts on migrating cortical neurons by binding to the very low density lipoprotein receptor (VLDLR), the apolipoprotein E receptor 2 (ApoER2; ref”
BackgroundProteins of the CNR Family Are Multiple Receptors for Reelin
Senzaki, K., Ogawa, M., & Yagi, T. (1999) · Cell · doi:10.1016/s0092-8674(00)81552-4 · Cited by 272
Brain Development in Normal and reeler Mice: the Phenotype
Lambert de Rouvroit, C., & Goffinet, A. M. (1998) · Advances in Anatomy Embryology and Cell Biology · doi:10.1007/978-3-642-72257-8_1 · Cited by 166
Cited by
The genetic basis of early T-cell precursor acute lymphoblastic leukaemia
Zhang, J., Ding, L., Holmfeldt, L., Wu, G., Heatley, S. L., Payne-Turner, D., Easton, J., Chen, X., Wang, J., Rusch, M., et al. (2012) · Nature · doi:10.1038/nature10725 · Cited by 1,596
“Four cases had non-synonymous mutations in RELN , which encodes reelin, a large secreted extracellular matrix protein involved in the regulation of neuronal migration, and which is mutated in the neurodevelopmental disorder autosomal recessive lissencephaly with cerebellar hypoplasi”
BackgroundMuhle, R., Trentacoste, S. V., & Rapin, I. (2004) · Pediatrics · doi:10.1542/peds.113.5.e472 · Cited by 1,207
Guerrini, R. (2006) · The Lancet · doi:10.1016/s0140-6736(06)68182-8 · Cited by 848
Sex-specific genetic architecture of human disease
Ober, C., Loisel, D. A., & Gilad, Y. (2008) · Nature Reviews Genetics · doi:10.1038/nrg2415 · Cited by 787
Genetics of austim: complex aetiology for a heterogeneous disorder
Folstein, S. E., & Rosen-Sheidley, B. (2001) · Nature Reviews Genetics · doi:10.1038/35103559 · Cited by 771
Consensus Paper: Pathological Role of the Cerebellum in Autism
Fatemi, S. H., Aldinger, K. A., Ashwood, P., Bauman, M. L., Blaha, C. D., Blatt, G. J., Chauhan, A., Chauhan, V., Dager, S. R., Dickson, P. E., et al. (2012) · The Cerebellum · doi:10.1007/s12311-012-0355-9 · Cited by 723
Role of the Reelin Signaling Pathway in Central Nervous System Development
Rice, D. S., & Curran, T. (2001) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.24.1.1005 · Cited by 667
Trekking across the Brain: The Journey of Neuronal Migration
Ayala, R., Shu, T., & Tsai, L.-H. (2007) · Cell · doi:10.1016/j.cell.2006.12.021 · Cited by 620
Searching for ways out of the autism maze: genetic, epigenetic and environmental clues
Persico, A. M., & Bourgeron, T. (2006) · Trends in Neurosciences · doi:10.1016/j.tins.2006.05.010 · Cited by 575
Malformations of cortical development: clinical features and genetic causes
Guerrini, R., & Dobyns, W. B. (2014) · The Lancet Neurology · doi:10.1016/s1474-4422(14)70040-7 · Cited by 513
Reelin, lipoprotein receptors and synaptic plasticity
Herz, J., & Chen, Y. (2006) · Nature Reviews Neuroscience · doi:10.1038/nrn2009 · Cited by 524
Extracellular Matrix: Functions in the Nervous System
Barros, C. S., Franco, S. J., & Muller, U. (2011) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a005108 · Cited by 506
Reelin promotes hippocampal dendrite development through the VLDLR/ApoER2-Dab1 pathway
Niu, S., Renfro, A., Quattrocchi, C. C., Sheldon, M., & D'Arcangelo, G. (2004) · Neuron · doi:10.1016/s0896-6273(03)00819-5 · Cited by 375
Reelin gene alleles and haplotypes as a factor predisposing to autistic disorder
Persico, A. M., D'Agruma, L., Maiorano, N., Totaro, A., Militerni, R., Bravaccio, C., Wassink, T. H., Schneider, C., Melmed, R., Trillo, S., et al. (2001) · Molecular Psychiatry · doi:10.1038/sj.mp.4000850 · Cited by 337
Reelin-mediated Signaling Locally Regulates Protein Kinase B/Akt and Glycogen Synthase Kinase 3β
Beffert, U., Morfini, G., Bock, H. H., Reyna, H., Brady, S. T., & Herz, J. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m209205200 · Cited by 306
The involvement of Reelin in neurodevelopmental disorders
Folsom, T. D., & Fatemi, S. H. (2013) · Neuropharmacology · doi:10.1016/j.neuropharm.2012.08.015 · Cited by 275
Reelin signaling is impaired in autism
Fatemi, S. H., Snow, A. V., Stary, J. M., Araghi-Niknam, M., Reutiman, T. J., Lee, S., Brooks, A. I., & Pearce, D. A. (2005) · Biological Psychiatry · doi:10.1016/j.biopsych.2004.12.018 · Cited by 280
The Reelin signaling pathway promotes dendritic spine development in hippocampal neurons
Niu, S., Yabut, O., & D'Arcangelo, G. (2008) · The Journal of Neuroscience · doi:10.1523/jneurosci.1917-08.2008 · Cited by 266
Deconstructing cortical folding: genetic, cellular and mechanical determinants
Llinares-Benadero, C., & Borrell, V. (2019) · Nature Reviews Neuroscience · doi:10.1038/s41583-018-0112-2 · Cited by 243
Reelin glycoprotein: structure, biology and roles in health and disease
Fatemi, S. H. (2005) · Molecular Psychiatry · doi:10.1038/sj.mp.4001613 · Cited by 241
Dysregulation of Reelin and Bcl-2 Proteins in Autistic Cerebellum
Fatemi, S. H., Stary, J. M., Halt, A. R., & Realmuto, G. R. (2001) · Journal of Autism and Developmental Disorders · doi:10.1023/a:1013234708757 · Cited by 212
Cognitive disruption and altered hippocampus synaptic function in Reelin haploinsufficient mice
QIU, S., KORWEK, K., PRATTDAVIS, A., PETERS, M., BERGMAN, M., & WEEBER, E. (2006) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2005.11.001 · Cited by 202
Genetics of intellectual disability
Ropers, H. H. (2008) · Current Opinion in Genetics & Development · doi:10.1016/j.gde.2008.07.008 · Cited by 199
Reelin and neuropsychiatric disorders
Ishii, K., Kubo, K.-I., & Nakajima, K. (2016) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2016.00229 · Cited by 185
More than cholesterol transporters: lipoprotein receptors in CNS function and neurodegeneration
Lane-Donovan, C., Philips, G. T., & Herz, J. (2014) · Neuron · doi:10.1016/j.neuron.2014.08.005 · Cited by 158
Role for Reelin in stabilizing cortical architecture
Frotscher, M. (2010) · Trends in Neurosciences · doi:10.1016/j.tins.2010.06.001 · Cited by 157
Reelin Is a Serine Protease of the Extracellular Matrix
Quattrocchi, C. C., Wannenes, F., Persico, A. M., Ciafré, S. A., D'Arcangelo, G., Farace, M. G., & Keller, F. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m106996200 · Cited by 154
New insights into Reelin-mediated signaling pathways
Lee, G. H., & D’Arcangelo, G. (2016) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2016.00122 · Cited by 144
Emerging topics in Reelin function
Förster, E., Bock, H. H., Herz, J., Chai, X., Frotscher, M., & Zhao, S. (2010) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2010.07222.x · Cited by 130
Sekine, K., Kubo, K.-I., & Nakajima, K. (2014) · Neuroscience Research · doi:10.1016/j.neures.2014.06.004 · Cited by 124
Reduced Blood Levels of Reelin as a Vulnerability Factor in Pathophysiology of Autistic Disorder
Fatemi, S. H., Stary, J. M., & Egan, E. A. (2002) · Cellular and Molecular Neurobiology · doi:10.1023/a:1019857620251 · Cited by 122
Olson, E. C., Kim, S., & Walsh, C. A. (2006) · The Journal of Neuroscience · doi:10.1523/jneurosci.3000-05.2006 · Cited by 123
Self-citationBeffert, U., Durudas, A., Weeber, E. J., Stolt, P. C., Giehl, K. M., Sweatt, J. D., Hammer, R. E., & Herz, J. (2006) · The Journal of Neuroscience · doi:10.1523/jneurosci.4566-05.2006 · Cited by 121
Reelin in the years: controlling neuronal migration and maturation in the mammalian brain
D'Arcangelo, G. (2014) · Advances in Neuroscience · doi:10.1155/2014/597395 · Cited by 120
Reelin deficiency causes granule cell dispersion in epilepsy
Haas, C. A., & Frotscher, M. (2010) · Experimental Brain Research · doi:10.1007/s00221-009-1948-5 · Cited by 96
The ApoE receptors Vldlr and Apoer2 in central nervous system function and disease
Lane-Donovan, C., & Herz, J. (2017) · Journal of Lipid Research · doi:10.1194/jlr.r075507 · Cited by 94
Similarities and differences in structure, expression, and functions of VLDLR and ApoER2
Reddy, S. S., Connor, T. E., Weeber, E. J., & Rebeck, W. (2011) · Molecular Neurodegeneration · doi:10.1186/1750-1326-6-30 · Cited by 93
Reelin-deficient mice show impaired neurogenesis and increased stroke size
Won, S. J., Kim, S. H., Xie, L., Wang, Y., Mao, X. O., Jin, K., & Greenberg, D. A. (2006) · Experimental Neurology · doi:10.1016/j.expneurol.2005.12.008 · Cited by 84
Methodological factors influencing measurement and processing of plasma reelin in humans
Lugli, G., Krueger, J. M., Davis, J. M., Persico, A. M., Keller, F., & Smalheiser, N. R. (2003) · BMC Biochemistry · doi:10.1186/1471-2091-4-9 · Cited by 60
Polymorphic GGC repeat differentially regulates human reelin gene expression levels
Persico, A. M., Levitt, P., & Pimenta, A. F. (2006) · Journal of Neural Transmission · doi:10.1007/s00702-006-0441-6 · Cited by 52
Meta-analyses of RELN variants in neuropsychiatric disorders
Chen, N., Bao, Y., Xue, Y., Sun, Y., Hu, D., Meng, S., Lu, L., & Shi, J. (2017) · Behavioural Brain Research · doi:10.1016/j.bbr.2017.05.028 · Cited by 44
TIMP-1 inhibits the proteolytic processing of Reelin in experimental epilepsy
Tinnes, S., Ringwald, J., & Haas, C. A. (2013) · The FASEB Journal · doi:10.1096/fj.12-224899 · Cited by 39
Brosda, J., Dietz, F., & Koch, M. (2011) · Neurobiology of Disease · doi:10.1016/j.nbd.2011.07.008 · Cited by 37
Do, H. T., Bruelle, C., Tselykh, T., Jalonen, P., Korhonen, L., & Lindholm, D. (2013) · Journal of Biological Chemistry · doi:10.1074/jbc.m113.500967 · Cited by 20
Metadata
- Authors
- Hong, S. E., Shugart, Y. Y., Huang, D. T., Shahwan, S. A., Grant, P. E., Hourihane, J. O., Martin, N. D. T., & Walsh, C. A.
- Venue
- Nature Genetics
- Published
- 2000-09-01
- Volume
- 26
- Issue
- 1
- Pages
- 93-96
- ISSN
- 1061-4036 (ISSN-L)
- 1546-1718
- OpenAlex
- W2156126807
- Cited by
- 884
- References
- 5
- FWCI
- 35.85
- Type
- journal article
- Language
- en
- Open access
- closed
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