Protection of mammalian telomeres

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Telomere Shortening and Tumor Formation by Mouse Cells Lacking Telomerase RNA

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TRF2 Protects Human Telomeres from End-to-End Fusions

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THE STABILITY OF BROKEN ENDS OF CHROMOSOMES IN ZEA MAYS

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Structure of the Ku heterodimer bound to DNA and its implications for double-strand break repair

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DNA damage triggers a prolonged p53-dependent G1 arrest and long-term induction of Cip1 in normal human fibroblasts.

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p53- and ATM-Dependent Apoptosis Induced by Telomeres Lacking TRF2

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Inhibition of telomerase limits the growth of human cancer cells

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Pot1, the Putative Telomere End-Binding Protein in Fission Yeast and Humans

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p53 Deficiency Rescues the Adverse Effects of Telomere Loss and Cooperates with Telomere Dysfunction to Accelerate Carcinogenesis

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Human telomeres contain two distinct Myb–related proteins, TRF1 and TRF2

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Long G Tails at Both Ends of Human Chromosomes Suggest a C Strand Degradation Mechanism for Telomere Shortening

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The 3′ to 5′ Exonuclease Activity of Mre11 Facilitates Repair of DNA Double-Strand Breaks

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A mutant with a defect in telomere elongation leads to senescence in yeast

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Telomerase activity in normal and malignant hematopoietic cells.

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Cellular Senescence

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Normal human chromosomes have long G-rich telomeric overhangs at one endPreprint

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Telomere shortening and apoptosis in telomerase-inhibited human tumor cells

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Components of the Ku‐dependent non‐homologous end‐joining pathway are involved in telomeric length maintenance and telomeric silencing

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Single-Stranded DNA Arising at Telomeres in cdc13 Mutants May Constitute a Specific Signal for the RAD9 Checkpoint

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Cell-cycle-regulated association of RAD50/MRE11/NBS1 with TRF2 and human telomeres

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Cdc13p: A Single-Strand Telomeric DNA-Binding Protein with a Dual Role in Yeast Telomere Maintenance

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DNA end-joining: from yeast to man

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Identification of Human Rap1

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Telomeric localization of TRF2, a novel human telobox protein

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Regulation of telomere length and function by a Myb-domain protein in fission yeast

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Agents that cause DNA double strand breaks lead to p16INK4a enrichment and the premature senescence of normal fibroblasts

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Yeast Ku as a Regulator of Chromosomal DNA End Structure

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Yeast Checkpoint Genes in DNA Damage Processing: Implications for Repair and Arrest

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Disruption of mRad50 causes embryonic stem cell lethality, abnormal embryonic development, and sensitivity to ionizing radiation

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Cdc13 Delivers Separate Complexes to the Telomere for End Protection and Replication

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DNA double-strand break repair proteins are required to cap the ends of mammalian chromosomes

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A DNA Damage Response Pathway Controlled by Tel1 and the Mre11 Complex

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Telomerase extends the lifespan of virus-transformed human cells without net telomere lengthening

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Telomere maintenance is dependent on activities required for end repair of double-strand breaks

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The terminal DNA structure of mammalian chromosomes

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Ku acts in a unique way at the mammalian telomere to prevent end joiningPreprint

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Ku is associated with the telomere in mammals

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Mammalian Ku86 protein prevents telomeric fusions independently of the length of TTAGGG repeats and the G‐strand overhang

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The Saccharomyces CDC 13 protein is a single-strand TG 1–3 telomeric DNA-binding protein in vitro that affects telomere behavior in vivo

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Genes involved in senescence and immortalization

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MRT-2 checkpoint protein is required for germline immortality and telomere replication in C. elegans

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Effects of DNA nonhomologous end-joining factors on telomere length and chromosomal stability in mammalian cells

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RAP1: a protean regulator in yeast

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The Saccharomyces telomere-binding protein Cdc13p interacts with both the catalytic subunit of DNA polymerase α and the telomerase-associated Est1 proteinPreprint

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Telomere Shortening Is Proportional to the Size of the G-rich Telomeric 3′-Overhang

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Stn1, a new Saccharomyces cerevisiae protein, is implicated in telomere size regulation in association with Cdc13.Preprint

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Strand-Specific Postreplicative Processing of Mammalian Telomeres

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Stn1, a new Saccharomyces cerevisiae protein, is implicated in telomere size regulation in association with Cdc13.

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Ten1 functions in telomere end protection and length regulation in association with Stn1 and Cdc13

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The p53-dependent G1 cell cycle checkpoint pathway and ataxia-telangiectasia.

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Structure of the TRFH Dimerization Domain of the Human Telomeric Proteins TRF1 and TRF2

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The function of a stem-loop in telomerase RNA is linked to the DNA repair protein Ku

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Living with Genome Instability: Plant Responses to Telomere Dysfunction

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t‐loops at trypanosome telomeres

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Role of T antigen interactions with p53 in tumorigenesis

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The Absence of the DNA-Dependent Protein Kinase Catalytic Subunit in Mice Results in Anaphase Bridges and in Increased Telomeric Fusions with Normal Telomere Length and G-Strand Overhang

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Interaction of human Ku70 with TRF2

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The Fission Yeast Taz1 Protein Protects Chromosomes from Ku-Dependent End-to-End Fusions

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The Mre11p/Rad50p/Xrs2p Complex and the Tel1p Function in a Single Pathway for Telomere Maintenance in Yeast

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Exonuclease activity is required for sequence addition and Cdc13p loading at a de novo telomere

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Telomeres of polytene chromosomes in a ciliated protozoan terminate in duplex DNA loops

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A low threshold level of expression of mutant-template telomerase RNA inhibits human tumor cell proliferation

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Telomere dynamics, end-to-end fusions and telomerase activation during the human fibroblast immortalization process

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Ku Binds Telomeric DNA in Vitro

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Human Papillomavirus E6 and E7: Proteins which deregulate the cell cycle

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DNA double-strand-break sensitivity, DNA replication, and cell cycle arrest phenotypes of Ku-deficient Saccharomyces cerevisiae

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Expression of mutant telomerase in immortal telomerase-negative human cells results in cell cycle deregulation, nuclear and chromosomal abnormalities and rapid loss of viability

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DNA-dependent protein kinase is not required for accumulation of p53 or cell cycle arrest after DNA damage.

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Telomere Capping--One Strand Fits All

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Cdc13 subcomplexes regulate multiple telomere functions.

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A New Connection at Human Telomeres: Association of the Mre11 Complex with TRF2Preprint

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Trypanosoma brucei: Conserved sequence organization 3′ to telomeric variant surface glycoprotein genes

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Telomeres and human disease: ageing, cancer and beyond

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DNA Damage Foci at Dysfunctional Telomeres

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Human Telomerase and Its Regulation

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Senescence Induced by Altered Telomere State, Not Telomere Loss

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Regulation of Telomerase by Telomeric Proteins

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Telomere length, stem cells and aging

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POT1 as a terminal transducer of TRF1 telomere length control

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Connecting Chromosomes, Crisis, and Cancer

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Homologous Recombination Generates T-Loop-Sized Deletions at Human Telomeres

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Hallmarks of senescence in carcinogenesis and cancer therapy

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Different telomere damage signaling pathways in human and mouse cells

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Telomere Position Effect in Human Cells

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