Recommendations for reporting tumor budding in colorectal cancer based on the International Tumor Budding Consensus Conference (ITBCC) 2016

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GRADE guidelines 6. Rating the quality of evidence—imprecision

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GRADE guidelines: 7. Rating the quality of evidence—inconsistency

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GRADE guidelines: 2. Framing the question and deciding on important outcomes

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GRADE guidelines: 8. Rating the quality of evidence—indirectness

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GRADE guidelines: 9. Rating up the quality of evidence

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Japanese Society for Cancer of the Colon and Rectum (JSCCR) Guidelines 2014 for treatment of colorectal cancer

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Tumour budding in colorectal carcinoma

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Colorectal cancer molecular biology moves into clinical practice

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Tumor budding in colorectal carcinoma: time to take notice

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Tumor Budding is a Strong and Reproducible Prognostic Marker in T3N0 Colorectal Cancer

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Tumor budding in colorectal cancer—ready for diagnostic practice?

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Systematic review and meta-analysis of the impact of tumour budding in colorectal cancer

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New Criteria for Histologic Grading of Colorectal Cancer

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Tumour budding: a promising parameter in colorectal cancer

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Expression profiling of budding cells in colorectal cancer reveals an EMT-like phenotype and molecular subtype switching

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APC mutation and tumour budding in colorectal cancer

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Tumour budding as prognostic factor in stage I/II colorectal carcinoma

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A three-tier classification system based on the depth of submucosal invasion and budding/sprouting can improve the treatment strategy for T1 colorectal cancer: a retrospective multicenter study

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Proposal for a 10-high-power-fields scoring method for the assessment of tumor budding in colorectal cancer

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Prognostic significance of tumor budding in rectal cancer biopsies before neoadjuvant therapy

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Tumor Budding as an Index to Identify High-Risk Patients with Stage II Colon Cancer

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Role of APAF‐1, E‐cadherin and peritumoural lymphocytic infiltration in tumour budding in colorectal cancer

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Tumor budding score based on 10 high-power fields is a promising basis for a standardized prognostic scoring system in stage II colorectal cancer

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Tumor Budding in Colorectal Carcinoma

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Intratumoral budding as a potential parameter of tumor progression in mismatch repair–proficient and mismatch repair–deficient colorectal cancer patients

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Pathologic predictive factors for lymph node metastasis in submucosal invasive (T1) colorectal cancer: a systematic review and meta-analysis

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Budding Is Useful to Select High-Risk Patients in Stage II Well-Differentiated or Moderately Differentiated Colon Adenocarcinoma

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Tumor Budding is an Independent Predictor of Outcome in AJCC/UICC Stage II Colorectal Cancer

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Management of T1 colorectal cancers after endoscopic treatment based on the risk stratification of lymph node metastasis

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Tumour budding in colorectal cancer: what do we know and what can we do?

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EURECCA colorectal: Multidisciplinary Mission statement on better care for patients with colon and rectal cancer in Europe

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Intra-tumoral budding in preoperative biopsy specimens predicts lymph node and distant metastasis in patients with colorectal cancer

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Prognostic value of immunohistochemical analysis of tumor budding in colorectal carcinoma.

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Partial Pathologic Response and Nodal Status as Most Significant Prognostic Factors for Advanced Rectal Cancer Treated With Preoperative Chemoradiotherapy

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Poorly differentiated clusters (PDCs) as a novel histological predictor of nodal metastases in pT1 colorectal cancer

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Cytokeratin immunohistochemistry improves interobserver variability between unskilled pathologists in the evaluation of tumor budding in T1 colorectal cancer

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The apoptotic and proliferation rate of tumour budding cells in colorectal cancer outlines a heterogeneous population of cells with various impacts on clinical outcome

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Proposed Objective Criteria for “Grade 3” in Early Invasive Colorectal Cancer

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Predictors of Lymph Node Metastasis in T1 Colorectal Carcinoma

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p16INK4a promoter methylation and 9p21 allelic loss in colorectal carcinomas: relation with immunohistochemical p16INK4a expression and with tumor budding

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Localised colon cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

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